OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Nephrology is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
A UMOD variant with intermediate effects	694
Mentorship in the lives of scholars	423
Kidney health within the broader non-communicable disease agenda	378
Engineered CAR macrophages target kidney inflammation	355
Making advance care planning easier for adults with kidney disease and their clinicians	328
Age-old musings: twenty-first century management of advanced kidney disease in older individuals	328
Role of the gut microbiota in the pathogenesis of IgA nephropathy	315
The GLP-1 receptor agonist revolution comes to nephrology	296
Uropathogen and host responses in pyelonephritis	241
Designing acute kidney injury clinical trials	228
Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions	226
Disaster preparedness for patients with kidney disease	209
Endoplasmic reticulum-mediated organelle crosstalk in kidney disease	189
Treatment of chronic kidney disease in older populations	187
Vaccination in patients with kidney failure: lessons from COVID-19	168
A single-cell atlas of DKD treatment responses	163
Daprodustat for anaemia in CKD	161
Roles of sensory receptors in non-sensory organs: the kidney and beyond	160
Beyond state borders: transforming dialysis care for undocumented immigrants	153
Genetic determinants of urine and plasma metabolite levels	150
GWAS scorecard prioritizes kidney genes using coding and regulatory variants	149
Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies	146
Consideration of sex differences is necessary to achieve health equity	141
Complosome — the intracellular complement system	137
Phosphate sensing via PTC glycolysis	135

Mutational signatures of ccRCC vary between geographical regions	134
Bringing Pride to nephrology	129
Publisher Correction: Sustainable Development Goals relevant to kidney health: an update on progress	129
Reducing preventable acute kidney injury in a hospital setting	129
Reference-trial-informed design to explore treatment effects in trial-underrepresented subgroups	126
Increasing diversity and inclusion in nephrology clinical trials	123
Clonal haematopoiesis and AKI	123
The effects of sex hormone therapy on kidney function	118
Informing clinical decision making during a pandemic — a call for better preparedness	116
The roles of hyaluronan in kidney development, physiology and disease	114
Menopause and chronic kidney disease	113
Aquaporin water channels: roles beyond renal water handling	109
Interferon blockade in lupus: effects on antiviral immunity	109
Benefits of actin cytoskeleton stabilization	105
Innovating dialysis through computational modelling of hollow-fibre haemodialysers	102
From mapping kidney function to mechanism and prediction	101
Identification of erythropoietin-producing cells	99
NUAK1 promotes kidney fibrosis	98
Design of a renal-sparing antifungal	95
Tertiary lymphoid organs contribute to kidney allograft rejection	93
Treatment of SLE with anti-CD19 CAR-T cells	92
Heat and health inequity: acting on determinants of health to promote heat justice	88
RNA-binding proteins and their role in kidney disease	82
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance)	81
From fat to filter: the effect of adipose tissue-derived signals on kidney function	80
The role of complement in kidney disease	80
Long-term health outcomes associated with hydration status	79
Salt substitution: opportunities and challenges for nephrology	77
Neutrophils and NETs in kidney disease	74
Pathological mechanisms of kidney disease in ageing	74
The evolving landscape of immune-mediated glomerular diseases	70
Author Correction: Chronic cardiovascular–kidney disorder: a new conceptual framework	70
Reaping the rewards of mechanistic discovery in glomerular disease	70
A golden year of innovative kidney disease therapeutics	67
An integrated approach towards a public health perspective on chronic kidney disease	65
MSC therapy for diabetic kidney disease and nephrotic syndrome	65
Network medicine: an approach to complex kidney disease phenotypes	64
A pathway of osmotic stress-induced necroptosis	62
Patient-centred approaches for the management of unpleasant symptoms in kidney disease	61
Reducing stress-induced CHOP is renoprotective	61
Drosophila melanogaster: a simple genetic model of kidney structure, function and disease	61
Combination therapy for kidney disease in people with diabetes mellitus	59
Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges	57
Consequence of microvascular inflammation in transplantation	56
Self-reactive innate-like B-1 cells infiltrate grafts	56
Ketogenic diet benefits in critically ill patients with sepsis	55
Transcatheter mitral valve repair in patients with CKD	53
The cilia mechanosensation debate gets (bio)physical	53
CKD-specific ASCVD risk prediction tools	53
GalNAc-T14-associated defects in B cell homing in IgA nephropathy	50

Educating primary healthcare providers about kidney disease	50
Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors	49
Consequences of famine and malnourishment on kidney health	49
Continuing kidney care in conflicts	45
Role of the cGAS–STING pathway in systemic and organ-specific diseases	45
Kidney complications of parasitic diseases	45
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney	45
Gene therapy in a model of nephrotic syndrome	44
Dietary protection of proximal tubules in diabetes	43
Mechanism of B cell survival in lupus nephritis	43
Nephrology education and training in Africa	41
Targeting IL-1Ra to attenuate fungal infection	41
Stem cell–kidney transplantation in Schimke immuno-osseous dysplasia	41
Multifaceted innovations needed to advance transplant nephrology	40
Mannose as a driver of γδ T cell kidney infiltration	39
Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome	38
Steps forward in the treatment of IgA nephropathy	38
The kidney is a novel target of metformin	37
Metabolic alterations in hereditary and sporadic renal cell carcinoma	37
IL-6 signalling contributes to the pathogenesis of uraemic calciphylaxis	37
Born too soon: lifelong kidney risks and the importance of early intervention	35
Chronic cardiovascular–kidney disorder: a new conceptual framework	35
A guide to gene–disease relationships in nephrology	34
Epithelial cell states associated with kidney and allograft injury	34
Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope	34
Role of necroptosis in kidney health and disease	34
Fasting induces structural and functional changes in the peritoneal membrane	32
A multidisciplinary approach to cardiorespiratory fitness in CKD	32
ALCAM–CD6 in lupus nephritis	31
Author Correction: Therapeutic advances in COVID-19	30
Insights into the impact of pregnancy on kidney disease	30
Derivation of collecting duct organoids	30
Renal nerves in physiology, pathophysiology and interoception	29
Author Correction: Regulatory T cells in autoimmune kidney diseases and transplantation	29
Fibroblast activation and heterogeneity in fibrotic disease	29
Tissue-resident memory T cells in the urogenital tract	27
Strategies to achieve gender equity in nephrology	27
From big data to smart decisions: artificial intelligence in kidney risk assessment	26
The impact of intrauterine growth restriction and prematurity on nephron endowment	26
The perils of misinformation: when health literacy goes awry	26
Exercise and chronic kidney disease: potential mechanisms underlying the physiological benefits	26
Leveraging data as a patient–scientist: frustrations and opportunities	26
Acute kidney injury in patients with burns	26
Switching off SOX9 for epithelial recovery after AKI	26
CD38 — a new target in renal immune disease	25
Experimental evidence for a pathogenic role of anti-PLA2R1 antibodies in membranous nephropathy	25
Crosstalk between glomeruli and tubules	24
The genetics of kidney stone disease and nephrocalcinosis	22
Hope for resistant hypertension through BrigHTN and PRECISION	22
Functional consequences of spatial, temporal and ligand bias of G protein-coupled receptors	22
Digital determinants of health: opportunities and risks amidst health inequities	22
Collagen formation, function and role in kidney disease	22
Impact of persistent conflict and destabilizing events on dialysis care	21
The impact of population ageing on the burden of chronic kidney disease	20
Nephrology and women’s health post-Roe v. Wade: we must do better	20
Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup	20
Chlorthalidone in advanced CKD	20