OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Nephrology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
A UMOD variant with intermediate effects	552
Multifaceted innovations needed to advance transplant nephrology	355
YAP and TAZ regulate stromal cell development	327
In vivo slit diaphragm dynamics in Drosophila	294
Genetics of posterior urethral valves	270
Wnt–Fzd signals put the brakes on nephrogenesis	269
Ferroptotic stress promotes the AKI to CKD transition	269
Targeting OSBPL7 restores cholesterol efflux	243
Daratumumab for AL amyloidosis	226
DPEP1 mediates neutrophil and monocyte influx	200
Mentorship in the lives of scholars	196
KIM-1 targeted extracellular vesicles for AKI	195
Mechanism of B cell survival in lupus nephritis	184
Gene therapy in a model of nephrotic syndrome	163
Progress in xenotransplantation: overcoming immune barriers	162
Opioids for chronic pain management in patients with dialysis-dependent kidney failure	158
Vaccination in patients with kidney failure: lessons from COVID-19	152
Stem cell–kidney transplantation in Schimke immuno-osseous dysplasia	151
Unmet care needs of minority groups on dialysis	146
EPO regulates antibody production via TFH cells	140
A recombinant fusion protein clears IgA deposits	140
Dietary protection of proximal tubules in diabetes	133
Embryo complementation to generate a humanized mesonephros in pigs	127
Unconventional T cells and kidney disease	126
Chronic cardiovascular–kidney disorder: a new conceptual framework	123

Mannose as a driver of γδ T cell kidney infiltration	123
Targeting IL-1Ra to attenuate fungal infection	121
Born too soon: lifelong kidney risks and the importance of early intervention	115
Approaches to raise awareness of CKD among patients and the general population	113
Lived experience is essential for innovation in biomedical research	112
The evolving complexity of the collecting duct renin–angiotensin system in hypertension	111
ECM remodelling by ADAMTS12 in fibrosis	108
The kidney is a novel target of metformin	108
Steps forward in the treatment of IgA nephropathy	108
Role of the gut microbiota in the pathogenesis of IgA nephropathy	108
Cross-species evolution of capsid libraries for gene delivery to the kidneys	105
Progression and outcomes of rare kidney diseases	105
The immunoregulatory roles of non-haematopoietic cells in the kidney	103
Kidney health within the broader non-communicable disease agenda	102
Author Correction: Conceptual advances and evolving terminology in acute kidney disease	101
Age-old musings: twenty-first century management of advanced kidney disease in older individuals	99
Home monitoring of patients with chronic kidney disease	99
Healthy ageing and the kidney — lessons from centenarians	96
Pulmonary hypertension and chronic kidney disease: prevalence, pathophysiology and outcomes	96
Polygenic scores and their applications in kidney disease	95
Making advance care planning easier for adults with kidney disease and their clinicians	89
Blockchain in nephrology	89
Epithelial cell states associated with kidney and allograft injury	88
Electronic patient-reported outcomes in chronic kidney disease	84
Advancing gender equity to improve kidney care for women: a patient perspective	82
A guide to gene–disease relationships in nephrology	82
Nephrology education and training in Africa	79
Big Data in Nephrology	76
Evolutionary genetics and acclimatization in nephrology	76
Expanding the therapy options for diabetic kidney disease	74
Determining lineage relationships in kidney development and disease	73
Kidneys control inter-organ homeostasis	73
Kidney disease as a medical complication of eating disorders	73
Cryopreservation breaks the organ transplant time barrier	72
Artificial intelligence-enabled decision support in nephrology	72
Uropathogen and host responses in pyelonephritis	70
Use of convalescent plasma in the treatment of COVID-19	65
Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions	63
Targeted identification of risk and treatment of diabetic kidney disease	63
The GLP-1 receptor agonist revolution comes to nephrology	63
Gut microbiome studies in CKD: opportunities, pitfalls and therapeutic potential	61
Disaster preparedness for patients with kidney disease	56
Disasters and kidney care: pitfalls and solutions	56
Treatment of chronic kidney disease in older populations	55
Therapeutic trials in adult FSGS: lessons learned and the road forward	54
The role of immune cells and mediators in preeclampsia	54
Endothelin receptor antagonists in chronic kidney disease	54
Equitable access to kidney transplants for Aboriginal and Torres Strait Islander people in Australia	49
Youth-onset type 2 diabetes mellitus: an urgent challenge	49
Sex differences in renal transporters: assessment and functional consequences	49

Role of biophysics and mechanobiology in podocyte physiology	48
Long COVID and kidney disease	47
Cardiac metabolic remodelling in chronic kidney disease	46
Glomerular hyperfiltration	46
Designing acute kidney injury clinical trials	46
Metabolic alterations in hereditary and sporadic renal cell carcinoma	45
Epidemiology of haemodialysis outcomes	45
Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome	44
The role of lysosomes in metabolic and autoimmune diseases	44
Advances in CRISPR therapeutics	44
Role of necroptosis in kidney health and disease	42
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative	42
Chronic kidney disease and the global public health agenda: an international consensus	41
Immune cell behaviour and dynamics in the kidney — insights from in vivo imaging	41
Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope	40
Applications of SGLT2 inhibitors beyond glycaemic control	39
The fibrogenic niche in kidney fibrosis: components and mechanisms	39
Advances in uromodulin biology and potential clinical applications	39
Kidney and heart failure outcomes associated with SGLT2 inhibitor use	38
Trajectories of kidney function in diabetes: a clinicopathological update	38
A spatial transcriptomic atlas of AKI in female mice	36
A multidisciplinary approach to cardiorespiratory fitness in CKD	36
Canagliflozin disrupts T cell activation	36
VISTA dampens T cell activation in injured kidney	35
Recipient APOL1 effects on transplant outcomes	34
An AQP1 variant is associated with peritoneal dialysis outcomes	34
Fasting induces structural and functional changes in the peritoneal membrane	32
Activin A in CKD-associated muscle wasting	32
Targeting glutamine use in RCC	32
Phagocytic properties of intercalated cells	31
FOXCs are master regulators of podocyte identity	29
Treating mild chronic hypertension in pregnancy	28
Derivation of collecting duct organoids	28
Bacteria caught in neutrophil and UMOD traps in urine	28
Renoprotective effects of sparsentan: clinical trial evidence in IgA nephropathy and FSGS	27
ALCAM–CD6 in lupus nephritis	27
Remodelling by macula densa cells	26
Protecting the kidney with probiotics	26
Basophils stoke the fire	26
Synchronization in the renal microcirculation	25
A single-cell atlas of DKD treatment responses	25
Circulating osteopontin mediates acute kidney injury-induced respiratory failure	24
Risk of kidney failure among patients with genetic kidney diseases	24
Interorgan communication networks in the kidney–lung axis	23
The Mesangial cell — the glomerular stromal cell	23
GWAS scorecard prioritizes kidney genes using coding and regulatory variants	23
Roles of sensory receptors in non-sensory organs: the kidney and beyond	22
Long-term lessons from EMPA-KIDNEY	22
Regulation of kidney fibrosis by ILC3s via a gut–kidney axis	21
Daprodustat for anaemia in CKD	21
Avenciguat reduces albuminuria in patients with chronic kidney disease	21
Considerations of sex as a binary variable in clinical algorithms	20
A guide to studying 3D genome structure and dynamics in the kidney	20
The realities of diagnosing and managing glomerular disease in low-income countries	20
Staying on track to achieve racial justice in kidney care	19
Multidisciplinary collaboration to improve neonatal kidney health	19
New insights into kidney crosstalk with distant organs	19
Intersectionality as a lens for achieving kidney health justice	19
Delivering on the potential of measuring nephron number in the clinic	17
Including sexual orientation and gender identity data to advance nephrology care	17
COVID-19 vaccination in patients receiving dialysis	17