OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Nephrology is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
A UMOD variant with intermediate effects	785
Age-old musings: twenty-first century management of advanced kidney disease in older individuals	589
Making advance care planning easier for adults with kidney disease and their clinicians	442
Mentorship in the lives of scholars	435
Engineered CAR macrophages target kidney inflammation	382
Role of the gut microbiota in the pathogenesis of IgA nephropathy	379
Endoplasmic reticulum-mediated organelle crosstalk in kidney disease	376
Inhibitory effects of oestradiol on ferroptosis may underlie sex differences in AKI	336
The changing landscape of kidney health and disease in Africa	283
Vaccination in patients with kidney failure: lessons from COVID-19	278
Uropathogen and host responses in pyelonephritis	259
The GLP-1 receptor agonist revolution comes to nephrology	217
Treatment of chronic kidney disease in older populations	213
Disaster preparedness for patients with kidney disease	202
Kidney health within the broader non-communicable disease agenda	190
Urine as a source of biomarkers and biological knowledge in chronic kidney disease	186
Designing acute kidney injury clinical trials	175
Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions	172
A single-cell atlas of DKD treatment responses	162
Daprodustat for anaemia in CKD	162
Genetic determinants of urine and plasma metabolite levels	159
GWAS scorecard prioritizes kidney genes using coding and regulatory variants	156
Beyond state borders: transforming dialysis care for undocumented immigrants	155
Consideration of sex differences is necessary to achieve health equity	148
Roles of sensory receptors in non-sensory organs: the kidney and beyond	145

Transport and barrier mechanisms that regulate ciliary compartmentalization and ciliopathies	141
Complosome — the intracellular complement system	138
Strategic rebalancing of kidney-related investments is key to implementing the WHO kidney health resolution	138
Phosphate sensing via PTC glycolysis	137
Increasing diversity and inclusion in nephrology clinical trials	134
Mutational signatures of ccRCC vary between geographical regions	132
Bringing Pride to nephrology	125
20 years of Nature Reviews Nephrology	122
Informing clinical decision making during a pandemic — a call for better preparedness	117
Reference-trial-informed design to explore treatment effects in trial-underrepresented subgroups	110
Reducing preventable acute kidney injury in a hospital setting	110
Clonal haematopoiesis and AKI	109
The effects of sex hormone therapy on kidney function	109
Menopause and chronic kidney disease	107
Interferon blockade in lupus: effects on antiviral immunity	101
Aquaporin water channels: roles beyond renal water handling	94
The roles of hyaluronan in kidney development, physiology and disease	91
Innovating dialysis through computational modelling of hollow-fibre haemodialysers	88
From mapping kidney function to mechanism and prediction	87
Identification of erythropoietin-producing cells	86
Tertiary lymphoid organs contribute to kidney allograft rejection	86
Design of a renal-sparing antifungal	82
NUAK1 promotes kidney fibrosis	80
Heat and health inequity: acting on determinants of health to promote heat justice	79
Treatment of SLE with anti-CD19 CAR-T cells	77
Guidelines for the use of economic evaluation to inform policies around access to treatment for kidney failure	77
Benefits of actin cytoskeleton stabilization	73
Salt substitution: opportunities and challenges for nephrology	70
Pathological mechanisms of kidney disease in ageing	70
Long-term health outcomes associated with hydration status	68
From fat to filter: the effect of adipose tissue-derived signals on kidney function	65
Neutrophils and NETs in kidney disease	65
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance)	65
RNA-binding proteins and their role in kidney disease	64
The role of complement in kidney disease	64
Reaping the rewards of mechanistic discovery in glomerular disease	63
Author Correction: Chronic cardiovascular–kidney disorder: a new conceptual framework	62
The evolving landscape of immune-mediated glomerular diseases	61
Network medicine: an approach to complex kidney disease phenotypes	60
Combination therapy for kidney disease in people with diabetes mellitus	58
A pathway of osmotic stress-induced necroptosis	57
Portable, wearable and implantable artificial kidney systems: needs, opportunities and challenges	56
MSC therapy for diabetic kidney disease and nephrotic syndrome	55
An integrated approach towards a public health perspective on chronic kidney disease	55
A golden year of innovative kidney disease therapeutics	54
Drosophila melanogaster: a simple genetic model of kidney structure, function and disease	54
CKD-specific ASCVD risk prediction tools	53
Consequence of microvascular inflammation in transplantation	53
Ketogenic diet benefits in critically ill patients with sepsis	53
Patient-centred approaches for the management of unpleasant symptoms in kidney disease	53

The cilia mechanosensation debate gets (bio)physical	52
Long COVID and the kidney	51
Consequences of famine and malnourishment on kidney health	51
GalNAc-T14-associated defects in B cell homing in IgA nephropathy	51
Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors	49
Transcatheter mitral valve repair in patients with CKD	49
PDGFRβ CAR T cells improve fibrosis in kidney disease models	49
Continuing kidney care in conflicts	48
Educating primary healthcare providers about kidney disease	47
Kidney complications of parasitic diseases	46
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney	45
Role of the cGAS–STING pathway in systemic and organ-specific diseases	45
Stem cell–kidney transplantation in Schimke immuno-osseous dysplasia	44
Dietary protection of proximal tubules in diabetes	43
Mechanism of B cell survival in lupus nephritis	42
Gene therapy in a model of nephrotic syndrome	40
Targeting IL-1Ra to attenuate fungal infection	39
Multifaceted innovations needed to advance transplant nephrology	37
Mannose as a driver of γδ T cell kidney infiltration	36
Steps forward in the treatment of IgA nephropathy	36
Cardiovascular mortality increases with stage of cardiovascular–kidney–metabolic syndrome	35
IL-6 signalling contributes to the pathogenesis of uraemic calciphylaxis	35
The kidney is a novel target of metformin	35
Epithelial cell states associated with kidney and allograft injury	34
Born too soon: lifelong kidney risks and the importance of early intervention	33
Clinical practice recommendations for primary hyperoxaluria: an expert consensus statement from ERKNet and OxalEurope	32
Chronic cardiovascular–kidney disorder: a new conceptual framework	30
A guide to gene–disease relationships in nephrology	30
Generation of self-assembling kidney progenitor assembloids	30
Role of necroptosis in kidney health and disease	30
Metabolic alterations in hereditary and sporadic renal cell carcinoma	30
Author Correction: Therapeutic advances in COVID-19	29
Fasting induces structural and functional changes in the peritoneal membrane	29
Derivation of collecting duct organoids	29
A multidisciplinary approach to cardiorespiratory fitness in CKD	29
Strategies to achieve gender equity in nephrology	28
ALCAM–CD6 in lupus nephritis	28
Leveraging data as a patient–scientist: frustrations and opportunities	28
Author Correction: Regulatory T cells in autoimmune kidney diseases and transplantation	28
Renal nerves in physiology, pathophysiology and interoception	27
The increasing burden of mild and moderate anaemia in CKD	27
Green nephrology: from evidence to action	27
The immunology of sepsis: translating new insights into clinical practice	24
Tissue-resident memory T cells in the urogenital tract	23
From big data to smart decisions: artificial intelligence in kidney risk assessment	23
Insights into the impact of pregnancy on kidney disease	22
The impact of intrauterine growth restriction and prematurity on nephron endowment	21
A guide to uraemic toxicity	21
Acute kidney injury in patients with burns	21
The perils of misinformation: when health literacy goes awry	21
Exercise and chronic kidney disease: potential mechanisms underlying the physiological benefits	20
Fibroblast activation and heterogeneity in fibrotic disease	20
Switching off SOX9 for epithelial recovery after AKI	20
CD38 — a new target in renal immune disease	19
Experimental evidence for a pathogenic role of anti-PLA2R1 antibodies in membranous nephropathy	19