OOIR: Observatory of International Research

Papers

(The median citation count of Therapeutic Advances in Musculoskeletal Disease is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Is there wastage in the research resources for ankylosing spondylitis? An analysis of clinical trial discontinuation and nonpublication outcome	158
Anti-sclerostin antibodies: a new frontier in fragility fractures treatment	85
Actigraphy-derived physical activity levels and circadian rhythm parameters in patients with psoriatic arthritis: relationship with disease activity, mood, age and BMI	45
The socioeconomic status of patients with ankylosing spondylitis and its association with the burden of the disease and permanent disability: a cross-sectional cluster analysis	42
Safety and efficacy of SHR4640 combined with febuxostat for primary hyperuricemia: a multicenter, randomized, double-blind, phase II study	41
An update on the use of conventional and biological disease-modifying anti-rheumatic drugs in hand osteoarthritis	37
Clinical and immunological study of Tofacitinib and Baricitinib in refractory Blau syndrome: case report and literature review	36
Comparable long-term retention rates and effects on bone mineral density of denosumab treatment in patients with osteoporosis with or without autoimmune inflammatory rheumatic diseases: real-life data	33
Big data analyses and individual health profiling in the arena of rheumatic and musculoskeletal diseases (RMDs)	32
Similarities and differences: disentangling the intersection between axial psoriatic arthritis and axial spondyloarthritis	32
Counting the costs: a nationwide study on healthcare use following an adalimumab biosimilar switch in >1300 inflammatory arthritis patients	31
Tocilizumab in visual involvement of giant cell arteritis: a multicenter study of 471 patients	30
Cardio-rheumatology: integrated care and the opportunities for personalized medicine	30
Comparison of remission criteria in patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs: results from a nationwide registry	29
Based on minimal clinically important difference values, a moderate dose of tanezumab may be a better option for treating hip or knee osteoarthritis: a meta-analysis of randomized controlled trials	29
The challenge of pharmacotherapy for musculoskeletal pain: an overview of unmet needs	26
Reduced bone mineral density in patients with idiopathic inflammatory myopathies: a case-control study	26
From advanced imaging to molecular insights: the state of the art in omics for axial spondyloarthritis	26
Calcineurin inhibitors in systemic sclerosis – a systematic literature review	26
Health disparities in rheumatoid arthritis	25
Wearable transcutaneous electrical nerve stimulation (actiTENS®) is effective and safe for the treatment of knee osteoarthritis pain: a randomized controlled trial versus weak opioids	24
Plasma calprotectin as a biomarker of ultrasound synovitis in rheumatoid arthritis patients receiving IL-6 antagonists or JAK inhibitors	24
Tofacitinib as an alternative therapy for refractory intestinal Behçet’s syndrome	22
Bone fragility: conceptual framework, therapeutic implications, and COVID-19-related issues	22
Real-world evidence to assess the effectiveness of platelet-rich plasma in the treatment of knee degenerative pathology: a prospective observational study	20

A glimpse into the future of systemic lupus erythematosus	19
Estimation of fracture risk by the FRAX tool in patients with systemic lupus erythematosus: a 10-year longitudinal validation study	19
The association between gout flares and monosodium urate burden assessed using musculoskeletal ultrasound in patients with gout	19
T-score discordance between hip and lumbar spine: risk factors and clinical implications	18
Stromal vascular fraction therapy for knee osteoarthritis: a systematic review	18
Future challenges in rheumatology – is telemedicine the solution?	18
Sjögren syndrome: looking forward to the future	18
Early knee OA definition–what do we know at this stage? An imaging perspective	18
Intramuscular methylprednisolone administration in hand osteoarthritis patients: a feasibility study to inform a randomized controlled trial	17
Effects of acupuncture versus placebo on clinical status and potential specific effects in Fibromyalgia: an umbrella review of 11 meta-analyses	17
Role of imaging for eligibility and safety of a-NGF clinical trials	17
Development and evaluation of a multivariable prediction model for clinical improvement in an established cohort of Colombian rheumatoid arthritis patients	17
Evaluation of local tissue peri-implant reaction in total knee arthroplasty failure cases	17
Advanced imaging techniques in crystal arthritis	17
Systemic lupus erythematosus is associated with increased risk of Parkinson’s disease	16
Treatment with adalimumab in patients with chronic inflammatory rheumatic diseases: a study of treatment trajectories on a patient level in routine care	16
Delayed treatment with a tumor necrosis factor alpha blocker associated with worse outcomes in patients with spondyloarthritis: data from the Czech National Registry ATTRA	16
Gout increases length of stay in patients hospitalized for heart failure exacerbation	16
Bone marrow edema in children: chronic nonbacterial osteomyelitis and its mimickers	15
Magnetic resonance imaging assessments for knee segmentation and their use in combination with machine/deep learning as predictors of early osteoarthritis diagnosis and prognosis	15
MRI lesions in SpA: a comparison with noninflammatory back pain using propensity score adjustment method	15
Gout therapy updated	14
Repurposed and investigational disease-modifying drugs in osteoarthritis (DMOADs)	14
Safety, tolerability, and efficacy of the PD-1 agonist antibody JNJ-67484703 in adults with active rheumatoid arthritis: results of a multicenter, double-blind, placebo-controlled, randomized, multipl	14
An oleuropein-based dietary supplement may improve joint functional capacity in older people with high knee joint pain: findings from a multicentre-RCT and post hoc analysis	14
A novel infrapatellar approach of ultrasound-guided intra-articular injection of the knee from both lateral and medial side: a case series	14
Mechanisms hypothesized for pain-relieving effects of exercise in fibromyalgia: a scoping review	14
The analysis of the pulmonary domain involvement in Sjögren’s disease	13
Circulating microRNAs differentiate fast-progressing from slow-progressing and non-progressing knee osteoarthritis in the Osteoarthritis Initiative cohort	13
Precision medicine in axial spondyloarthritis: current opportunities and future perspectives	13
Risk factors associated with the occurrence of total knee arthroplasty in patients with knee osteoarthritis: a nested case–control study	13
Precision medicine using molecular-target drugs in psoriatic arthritis	12
Muscle health in ankylosing spondylitis: effects of disease duration, inflammation, education level, and spinal mobility on skeletal muscle atrophy	12
A broad look into the future of rheumatoid arthritis	12
Effects of adipose-derived mesenchymal stem cell conditioned medium on human tenocytes exposed to high glucose	12
A glance into the future of myositis therapy	12
Immunogenicity and safety of inactivated and mRNA COVID-19 vaccines in patients with systemic lupus erythematosus	12
Latest insights in disease-modifying osteoarthritis drugs development	12
Metabolic syndrome and psoriatic arthritis: the role of weight loss as a disease-modifying therapy	12
SARS-CoV-2 vaccination willingness and predictors in patients with chronic inflammatory rheumatic diseases (CIRD) and without CIRD	11
Factors associated with radiographic progression in rheumatoid arthritis starting biological diseases modifying anti-rheumatic drugs (bDMARDs)	11
Achievement of higher thresholds of clinical responses and lower levels of disease activity is associated with improvements in workplace and household productivity in patients with axial spondyloarthr	11
Medication holidays in osteoporosis: evidence-based recommendations from the Italian guidelines on ‘Diagnosis, risk stratification, and continuity of care of fragility fractures’ based on a systematic	11
Increased risks of aortic regurgitation and atrial fibrillation in radiographic axial spondyloarthritis patients: a 10-year nationwide cohort study	11
Association between bone trace elements and osteoporosis in older adults: a cross-sectional study	10
Measuring sedentary behavior using waist- and thigh-worn accelerometers and inclinometers – are the results comparable?	10
Uveitis in patients with axial spondyloarthritis or psoriatic arthritis: a post hoc analysis from placebo-controlled phase III studies with secukinumab	10
The application of machine learning in early diagnosis of osteoarthritis: a narrative review	10
Osteoporosis in 10 years time: a glimpse into the future of osteoporosis	9
High inflammatory burden predicts cardiovascular events in patients with axial spondyloarthritis: a long-term follow-up study	9

Tofacitinib in early active axial spondyloarthritis: protocol of a randomized double-blind, placebo-controlled, multicenter phase IV study, FASTLANE	9
Ultrasound-detected inflammation is more common in clinically manifest hand osteoarthritis than in painless bony enlarged finger joints: subanalysis of the population-based Bruneck study	9
Higher body mass index is associated with a lower iloprost infusion rate tolerance and higher iloprost-related adverse events in patients with systemic sclerosis	9
Impact of obesity on clinical outcomes and treatment continuation in rheumatoid arthritis patients receiving non-TNF-targeted therapies	9
Successful treatment of sirolimus in a Chinese patient with refractory LN and APS: a case report	9
To flare or not to flare: patients’ and rheumatologists’ perceptions on the on-flare retreatment strategy of rituximab in rheumatoid arthritis	8
Bone fragility during the COVID-19 pandemic: the role of macro- and micronutrients	8
The burden of low back pain in children and adolescents with overweight and obesity: from pathophysiology to prevention and treatment strategies	8
Zoledronic acid does not slow spinal radiographic progression of osteoarthritis in postmenopausal women with osteoporosis and radiographic osteoarthritis	8
Association between impaired lung function and risk of spondyloarthritis: a cross-sectional study in the UK Biobank	8
Is there still a place for methotrexate in severe psoriatic arthritis?	8
Meibomian gland dropout of upper eyelids as a novel biomarker for early diagnosis of primary Sjögren’s syndrome: a pilot study	8
Orthopaedic physicians’ awareness, diagnostic challenges and referral barriers in axial spondyloarthritis: insights from a nationwide survey in Germany	7
The impact of psoriatic arthritis on quality of life: a systematic review	7
The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to severe psoriatic arthri	7
Incidence rate of and risk factors for glomerulonephritis in patients with axial spondyloarthritis: a nationwide population-based study	7
New insights in lower limb reconstruction strategies	7
Validation of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in ANA-positive Chinese patients	7
Comparison of the efficacy and risk of discontinuation between non-TNF-targeted treatment and a second TNF inhibitor in patients with rheumatoid arthritis after first TNF inhibitor failure	7
Comparison of clinical efficiency between intra-articular injection of platelet-rich plasma and hyaluronic acid for osteoarthritis: a meta-analysis of randomized controlled trials	7
Retraction notice	7
Risk of ischaemic stroke among new users of glucosamine and chondroitin sulphate: a nested case–control study	7
Advancing artificial intelligence in rheumatology from evidence to practice	7
SCORE2 is superior to SCORE in predicting the presence of carotid plaques and intima-media thickness in rheumatoid arthritis patients: a cross-sectional study using carotid ultrasound	7
Predictive model to identify multiple failure to biological therapy in patients with rheumatoid arthritis	7
Intra-articular placebo effect in the treatment of knee osteoarthritis: a survey of the current clinical evidence	6
Effectiveness of high-frequency repetitive transcranial magnetic stimulation combined with quadriceps strength training in the treatment of knee osteoarthritis: a randomized controlled trial	6
A prognostic immune nutritional index can predict all-cause mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitis	6
Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis	6
Impact of bimekizumab and certolizumab pegol on efficacy, safety and osteoblastic activity in radiographic axial spondyloarthritis: results from a phase IIa, multicentre, randomised, double-blind, exp	6
Neuro-PIMS-TS: a single case report and review of the literature	6
Relationship between onset of psoriasis and spondyloarthritis symptoms with clinical phenotype and diagnosis: data from REGISPONSER registry	6
Osteosarcopenia and Long-COVID: a dangerous combination	6
Impact of csDMARDs adherence on clinical remission in patients with new-onset inflammatory arthritis: a prospective cohort study from the ELECTRA database	6
A glance into the future of gout	6
Uveitis in peripheral spondyloarthritis patients: an ancillary analysis of the ASAS-PerSpA study	6
A broad look into the future of systemic sclerosis	6
Managing inadequate response to initial anti-TNF therapy in rheumatoid arthritis: optimising treatment outcomes	6
Cardiovascular risk associated with allopurinol or benzbromarone treatment in patients with gout	6
Identifying global trends from case reports of fibrodysplasia ossificans progressiva: a scoping review	5
Clinical characteristics of myositis patients with isolated anti-U1 ribonucleoprotein antibody resemble immune-mediated necrotizing myopathy	5
Capsular stem cell function and tissue composition are associated with symptoms and radiographic severity in people with knee osteoarthritis	5
Monotherapy or combination therapy in PsA: current aspects	5
Mortality related to COVID-19 in patients with rheumatic and musculoskeletal diseases, first wave of the outbreak: a single-center study	5
Hip replacement in femoral neck fractures: the role of cementation and its technical difficulties	5
Double positivity for anti-dsDNA and anti-Sm antibodies represents higher disease activity in systemic lupus erythematosus	5
Effects of TNF-α inhibition versus secukinumab on active ultrasound-confirmed enthesitis in psoriatic arthritis	5
RAGing ahead in rheumatology: new language model architectures to tame artificial intelligence	5
A pilot study on deep learning-based grading of corners of vertebral bodies for assessment of radiographic progression in patients with ankylosing spondylitis	5
Innovations in Genicular Outcomes Registry (IGOR): protocol for a real-world registry study of treatments for knee osteoarthritis	5
Changes in ultrasound imaging of joints, entheses, bursae and tendons 24 and 48 h after adjusted weight training	5
Utilising a non-surgical intervention in the knee osteoarthritis care pathway: a 6-year retrospective audit on NHS patients	4
Acute effects of exercise on pain symptoms, clinical inflammatory markers and inflammatory cytokines in people with rheumatoid arthritis: a systematic literature review	4
Real-life short-term effectiveness of anti-osteoporotic treatments: a longitudinal cohort study	4
Vertebral fractures and bone health in patients with chronic non-bacterial osteomyelitis at disease onset: insights from the monocentric CAMELOT cohort	4
The role of adipose-derived mesenchymal stem cells in knee osteoarthritis: a meta-analysis of randomized controlled trials	4
Rheumatoid arthritis disease activity and adverse events in patients receiving tofacitinib or tumor necrosis factor inhibitors: a post hoc analysis of ORAL Surveillance	4
Regenerative medicine for early osteoarthritis	4
Concentric or eccentric physical activity for patients with symptomatic osteoarthritis of the knee: a randomized prospective study	4
Latest advancements in imaging techniques in OA	4
Association between baseline cardiovascular risk and incidence rates of major adverse cardiovascular events and malignancies in patients with psoriatic arthritis and psoriasis receiving tofacitinib	4
Clinical and immunological long-term outcomes after autologous hematopoietic stem cell transplantation in systemic sclerosis: a retrospective single-center experience	4
Major adverse cardiovascular events or venous thromboembolism in patients with rheumatoid arthritis initiating biological or targeted synthetic disease-modifying antirheumatic drugs: a nationwide, pop	4
Cardiovascular comorbidities in psoriatic arthritis: state of the art	4
Deep learning meets chest X-rays: a promising approach for predicting future compression fracture risk	4