OOIR: Observatory of International Research

Papers

(The H4-Index of Experimental and Therapeutic Medicine is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Proteomic analysis of human umbilical cord serum exosomes using mass spectrometry and preliminary study of their biological activities in liver cancer cell lines	177
Expression of TMED3 is independently associated with colorectal cancer prognosis	146
Novel variants identified in a three‑generation family with concomitant exotropia	75
PINCH1 knockout aggravates myocardial infarction in mice via mediating the NF‑κB signaling pathway	59
Pediatric esophageal stenoses: Challenges and new surgical device promoting tension‑free esophageal anastomosis	56
Vaccine development for zoonotic viral diseases caused by positive‑sense single‑stranded RNA viruses belonging to the Coronaviridae and Togaviridae families (Review)	53
Exploring medical terminology inexpediencies: Tripledemic vs. triple epidemic	52
Electrochemical monitoring of bronchial inflammation in pediatric athletes: A prospective study	52
Upregulation of osteoprotegerin inhibits tert‑butyl hydroperoxide‑induced apoptosis of human chondrocytes	50
Probable progressive supranuclear palsy in a patient with chronic schizophrenia: A case report	46
Risk factors for the in‑hospital and 1‑year mortality of elderly patients hospitalized due to COVID‑19‑related pneumonia	45
MicroRNA‑4327 regulates TGF‑β1 stimulation of matrix metalloproteinase‑13 expression via CREB‑binding protein‑mediated Runx2 acetylation in human osteoblasts	45
Rosiglitazone ameliorates acute hepatic injury via activating the Nrf2 signaling pathway and inhibiting activation of the NLRP3 inflammasome	43
Epigenetic regulation mechanism of DNA methylation and miRNAs on the expression of the ALOX5AP gene in patients with ischemic stroke	42
Genetic analysis of recurrent parthenogenesis: A case report and literature review	41
Isorhamnetin attenuates the proliferation, invasion, migration and fibrosis of keloid fibroblasts by targeting S1PR1	41
Anti‑epileptic mechanism of isopimaric acid from Platycladi cacumen based on network pharmacology, molecular docking and biological validation	41
Magnetic resonance imaging of a pediatric case of arthritis associated with acute lymphoblastic leukemia: A case report	41
Advances in cellular senescence in idiopathic pulmonary fibrosis (Review)	39
Protective effects of astaxanthin on particulate matter 2.5‑induced senescence in HaCaT keratinocytes via maintenance of redox homeostasis	37
Association of vitamin D receptor gene TaqI polymorphism with Alzheimer's disease in a Southeastern European Caucasian population	36
Salidroside inhibits renal ischemia/reperfusion injury‑induced ferroptosis by the PI3K/AKT signaling pathway	35
Fate of hematopoietic stem cells determined by Notch1 signaling (Review)	35
Erdheim‑Chester disease of multisystem involvement with delayed diagnosis: A case report and literature review	34
Paeonol suppresses lipid formation and promotes lipid degradation in adipocytes	34

Effects of dexmedetomidine on postoperative pain and early cognitive impairment in older male patients undergoing laparoscopic cholecystectomy	33
Identification and antibiotic susceptibility of microorganisms isolated from diabetic foot ulcers: A pathological aspect	32
Differential expression profiles of miRNA in granulomatous lobular mastitis and identification of possible biomarkers	31
Inhibition of cell survival and invasion by Tanshinone IIA via FTH1: A key therapeutic target and biomarker in head and neck squamous cell carcinoma	31
ADAM metallopeptidase domain 10 knockdown enables podocytes to resist high glucose stimulation by inhibiting pyroptosis via MAPK pathway	31
CIP2A interacts with AKT1 to promote the malignant biological behaviors of oral squamous cell carcinoma by upregulating the GSK‑3β/β‑catenin pathway	30
Overactive bladder: A review and update	30
Combination ofSophora flavescensalkaloids and Panax quinquefolium saponins modulates different stages of experimental autoimmune myocarditis via the NF‑κB and TGF‑β1 pathways	30