OOIR: Observatory of International Research

Papers

(The median citation count of Asian Journal of Pharmaceutical Sciences is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Charge adaptive phytochemical-based nanoparticles for eradication of methicillin-resistant staphylococcus aureus biofilms	307
Spatiotemporal transformable nano-assembly for on-demand drug delivery to enhance anti-tumor immunotherapy	219
Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment	121
Versatile applications of deep eutectic solvents in drug discovery and drug delivery systems: Perspectives and opportunities	102
Application of chitosan-based nanoparticles in skin wound healing	90
Recent advances in cell membrane-based biomimetic delivery systems for Parkinson’s disease: Perspectives and challenges	84
Regulatory role of long non coding RNAs (lncRNAs) in neurological disorders: From novel biomarkers to promising therapeutic strategies	81
CaCO3-encircled hollow CuS nanovehicles to suppress cervical cancer through enhanced calcium overload-triggered mitochondria damage	75
Cell membrane-coated mRNA nanoparticles for enhanced delivery to dendritic cells and immunotherapy	70
Hyaluronic acid conjugates with controlled oleic acid substitution as new nanomaterials for improving ocular co-delivery of cyclosporine A and oleic acid	66
pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma	64
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection	57
Penetrative Biomimetic Nanovehicle Boosts Immunotherapy in Triple-Negative Breast Cancer via SOS1 Blockade	57
Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment	53
Improving treatment for Parkinson's disease: Harnessing photothermal and phagocytosis-driven delivery of levodopa nanocarriers across the blood-brain barrier	50
Structure based release kinetics analysis of doxazosin mesylate sustained-release tablets using micro-computed tomography	48
Publisher's Note	43
Comparison of virus-capsid mimicking biologic-shell based versus polymeric-shell nanoparticles for enhanced oral insulin delivery	43
Blockade of neutrophil recruitment to tumor sites based on sialic acid-modified nanoplatforms enhances the efficacy of checkpoint blockade immunotherapy	40
Preliminary delivery efficiency prediction of nanotherapeutics into crucial cell populations in bone marrow niche	36
Advanced Strategies of Covalent Organic Framework Nanomedicines in Targeting and Overcoming Biological Barriers	36
Alantolactone-loaded chitosan/hyaluronic acid nanoparticles suppress psoriasis by deactivating STAT3 pathway and restricting immune cell recruitment	35
mRNA vaccines: Past, present, future	35
Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin	35
Fenton metal nanomedicines for imaging-guided combinatorial chemodynamic therapy against cancer	35

Immunotherapeutic hydrogel for co-delivery of STAT3 siRNA liposomes and lidocaine hydrochloride for postoperative comprehensive management of NSCLC in a single application	33
Enhancing chemoimmunotherapy for colorectal cancer with paclitaxel and alantolactone via CD44-Targeted nanoparticles: A STAT3 signaling pathway modulation approach	33
Nanoparticle-mediated synergistic anticancer effect of ferroptosis and photodynamic therapy: Novel insights and perspectives	32
Electrically conductive “SMART” hydrogels for on-demand drug delivery	32
Commentary of the mRNA vaccines COVID-19	31
Polymeric microneedle‐mediated sustained release systems: Design strategies and promising applications for drug delivery	30
Neutrophil-targeted liposomal platform: A shift in novel approach for early detection and treatment of cancer metastasis	29
Amphiphilic lipid-peptide engineered placenta-derived mesenchymal stem cells for liver fibrosis treatment	28
Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases	28
One-pot preparation of nanodispersion with readily available components for localized tumor photothermal and photodynamic therapy	28
High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis	26
Vat-based photopolymerization 3D printing: From materials to topical and transdermal applications	26
Design and fabrication of r-hirudin loaded dissolving microneedle patch for minimally invasive and long-term treatment of thromboembolic disease	26
Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system	25
Anti-EpCAM functionalized graphene oxide vector for tumor targeted siRNA delivery and cancer therapy	25
Intravitreal long-term sustained ranibizumab delivery using injectable microgel-embedded hydrogel	24
Liposomal remdesivir inhalation solution for targeted lung delivery as a novel therapeutic approach for COVID-19	24
Insights on drug and gene delivery systems in liver fibrosis	23
Targeted hyperalkalization with NaOH-loaded starch implants enhances doxorubicin efficacy in tumor treatment	23
A self-assembled nano-spray formulation for synergistic therapy of anti-inflammation and skin repair	22
A practical strategy to subcutaneous administered in-situ gelling co-delivery system of arsenic and retinoic acid for the treatment of acute promyelocytic leukemia	22
Recent progress of ferroptosis in cancers and drug discovery	22
Ionic liquids as the effective technology for enhancing transdermal drug delivery: Design principles, roles, mechanisms, and future challenges	21
Correction to “Folic acid-conjugated liposomal vincristine for multidrug resistant cancer therapy”	21
Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis	21
Relaxin-encapsulated polymeric metformin nanoparticles remodel tumor immune microenvironment by reducing CAFs for efficient triple-negative breast cancer immunotherapy	20
Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis	20
Additive manufacturing of sustainable biomaterials for biomedical applications	19
Overcoming corneal barriers: Posaconazole loaded cationic surfactant vesicles for enhanced ocular permeability and anti-fungal efficacy	19
Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders	19
A novel fixed-combination timolol-netarsudil-latanoprost ophthalmic solution for the treatment of glaucoma and ocular hypertension	19
Mimicking natural cholesterol assimilation to elevate the oral delivery of liraglutide for type II diabetes therapy	19
Synergistic chemotherapy/PTT/oxygen enrichment by multifunctional liposomal polydopamine nanoparticles for rheumatoid arthritis treatment	17
Functionalized chitosan as nano-delivery platform for CRISPR-Cas9 in cancer treatment	17
Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems	17
Advances in the development of amorphous solid dispersions: The role of polymeric carriers	16
Antibacterial biomaterials for skin wound dressing	16
Surface-engineered liposomes for dual-drug delivery targeting strategy against methicillin-resistant Staphylococcus aureus (MRSA)	16
Monitoring the in vivo siRNA release from lipid nanoparticles based on the fluorescence resonance energy transfer principle	16
Treatment of colorectal cancer by anticancer and antibacterial effects of hemiprotonic phenanthroline-phenanthroline+ with nanomicelle delivery	16
Endosomal disruption by co-encapsulating gentamicin in lipid nanoparticles for efficient siRNA delivery and cancer therapy	16
Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider	15
Lignin-assisted construction of sub-10 nm supramolecular self-assembly for photothermal immunotherapy and potentiating anti-PD-1 therapy against primary and distant breast tumors	15
Design strategies, advances and future perspectives of colon-targeted delivery systems for the treatment of inflammatory bowel disease	15
Rapid and effective treatment of traumatic spinal cord injury using stem cell derived exosomes	14
“NIR-triggered ROS storage” photodynamic intraocular implant for high-efficient and safe posterior capsular opacification prevention	14
Advanced drug delivery platforms target cancer stem cells	14
A biomimetic spore nanoplatform for boosting chemodynamic therapy and bacteria-mediated antitumor immunity for synergistic cancer treatment	14
Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease	14
Design of pH-responsive antimicrobial peptide melittin analog-camptothecin conjugates for tumor therapy	14

Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury	14
Non-cytotoxic nanoparticles re-educating macrophages achieving both innate and adaptive immune responses for tumor therapy	13
EVs-mediated delivery of CB2 receptor agonist for Alzheimer's disease therapy	13
Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition: Harnessing the power of nanotheranostics	13
Enhanced delivery efficiency and sustained release of biopharmaceuticals by complexation-based gel encapsulated coated microneedles: rhIFNα-1b example	13
All-stage targeted nanodiscs for glioma treatment by inducing cuproptosis and apoptosis of cancer cells and cancer stem cells	12
Amphiphilic small molecular mates match hydrophobic drugs to form nanoassemblies based on drug-mate strategy	12
Advances in nanotechnology for the diagnosis and management of metabolic dysfunction-associated steatotic liver disease	12
Multifunctional self-delivery micelles targeting the invasion-metastasis cascade for enhanced chemotherapy against melanoma and the lung metastasis	11
Design, preparation and pharmacodynamics of ICG-Fe(Ⅲ) based HCPT nanocrystals against cancer	11
Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy	11
Implantation of hydrogel-liposome nanoplatform inhibits glioblastoma relapse by inducing ferroptosis	11
Revamping anti-cGAS-STING therapy via an injectable thermo-responsive supramolecular hydrogel for pathological retinal angiogenesis	11
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug	11
Insights into microscopic fabrication, macroscopic forms and biomedical applications of alginate composite gel containing metal-organic frameworks	11
Single-dose oral administration of drug-loaded magnetic 3D-printed microbullets for eradication of Helicobacter pylori	10
Nanotechnologies meeting natural sources: Engineered lipoproteins for precise brain disease theranostics	10
CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia	10
IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity	10
Protein corona mediated liposomal drug delivery for bacterial infection management	10
Targeted degradation of LRG1 to attenuate renal fibrosis	10
Metal-Organic Frameworks as Therapeutic Chameleons: Revolutionizing the Cancer Therapy Employing Novel Nanoarchitectonics	10
New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus	9
Delivery strategies for CRISPR/Cas genome editing tool for retinal dystrophies: challenges and opportunities	9
Exosome-membrane and polymer-based hybrid-complex for systemic delivery of plasmid DNA into brains for the treatment of glioblastoma	9
Amphotericin B release rate is the link between drug status in the liposomal bilayer and toxicity	9
Role of the cation-chloride-cotransporters in the circadian system	9
Roles of effective stabilizers in improving oral bioavailability of naringenin nanocrystals: Maintenance of supersaturation generated upon dissolution by inhibition of drug dimerization	9
MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation	9
Light-stimulated smart thermo-responsive constructs for enhanced wound healing: A streamlined command approach	8
Next generation of neurological therapeutics: Native and bioengineered extracellular vesicles derived from stem cells	8
Osteoimmunity-regulating biomaterials promote bone regeneration	8
Polydopamine-coated i-motif DNA/Gold nanoplatforms for synergistic photothermal-chemotherapy	8
Celastrol-loaded metal-phenolic nanozymes integrated microneedles with ROS scavenging and anti-inflammatory activities for psoriasis treatment	8
Extracellular Vesicles in Cancer Immunotherapy: Therapeutic, Challenges and Clinical Progress	7
Emerging pro-drug and nano-drug strategies for gemcitabine-based cancer therapy	7
Small extracellular vesicles encapsulating lefty1 mRNA inhibit hepatic fibrosis	7
Elaborately engineering of a dual-drug co-assembled nanomedicine for boosting immunogenic cell death and enhancing triple negative breast cancer treatment	7
Engineered exosomes-based theranostic strategy for tumor metastasis and recurrence	7
Codelivery of apigenin, FdUMP and CD276 antibody synergistic inhibit colorectal cancer by ferroptosis-apoptosis-pyroptosis and CD276 blockade	7
Functionalized lipid nanoparticles modulate the blood-brain barrier and eliminate α-synuclein to repair dopamine neurons	7
Leveraging immunoliposomes as nanocarriers against SARS-CoV-2 and its emerging variants	7
Spatiotemporally co-delivery of triple therapeutic drugs via HA-coating nanosystems for enhanced immunotherapy	7
Reversing ferroptosis resistance by MOFs through regulation intracellular redox homeostasis	7
Gp350-anchored extracellular vesicles: promising vehicles for delivering therapeutic drugs of B cell malignancies	7
Recent advances in spatio-temporally controllable systems for management of glioma	7
Doxorubicin hydrochloride and L-arginine co-loaded nanovesicle for drug resistance reversal stimulated by near-infrared light	7
Lipid nanoparticle-mediated CRISPR/Cas9 gene editing and metabolic engineering for anticancer immunotherapy	6
In situ injectable hydrogel encapsulating Mn/NO-based immune nano-activator for prevention of postoperative tumor recurrence	6
Fine-tuning the activation behaviors of ternary modular cabazitaxel prodrugs for efficient and on-target oral anti-cancer therapy	6
Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury	6
Phytoestrogen-derived multifunctional ligands for targeted therapy of breast cancer	6
Biomimetic nanoparticles co-deliver hirudin and lumbrukinase to ameliorate thrombus and inflammation for atherosclerosis therapy	6
Exosomes: Emerging implementation of nanotechnology for detecting and managing novel corona virus- SARS-CoV-2	6
Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy	6
Liposome cocktail activator modulates hepatocytes and remodels the microenvironment to mitigate acute liver failure	5
Small molecular chelator for comprehensive regulation of tumor lactate levels in synergy with photodynamic therapy for cancer treatment	5
Biomimetic biomineralization nanoplatform-mediated differentiation therapy and phototherapy for cancer stem cell inhibition and antitumor immunity activation	5
Carrier-free prodrug nanoparticles based on dasatinib and cisplatin for efficient antitumor in vivo	5
Targeted protein degradation with small molecules for cancer immunotherapy	5
Albumin nanoassembly bi-directionally manipulated ferroptosis in tumor and CD8+ T cells for triple-negative breast cancer therapy	5
Local dose-dense chemotherapy for triple-negative breast cancer via minimally invasive implantation of 3D printed devices	5
Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs	5
Nucleobase-crosslinked poly(2-oxazoline) nanoparticles as paclitaxel carriers with enhanced stability and ultra-high drug loading capacity for breast cancer therapy	5
Biofunctional supramolecular injectable hydrogel with spongy-like metal-organic coordination for effective repair of critical-sized calvarial defects	5
Enhancing temozolomide in vivo stability and efficacy through hybrid nanoconjugate approach for improved glioblastoma multiforme treatment	5