OOIR: Observatory of International Research

Papers

(The median citation count of Asian Journal of Pharmaceutical Sciences is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Phytoestrogen-derived multifunctional ligands for targeted therapy of breast cancer	398
Recent progress of ferroptosis in cancers and drug discovery	291
Charge adaptive phytochemical-based nanoparticles for eradication of methicillin-resistant staphylococcus aureus biofilms	190
Biomimetic nanoparticles co-deliver hirudin and lumbrukinase to ameliorate thrombus and inflammation for atherosclerosis therapy	163
Insights on drug and gene delivery systems in liver fibrosis	100
Recent advances of sorafenib nanoformulations for cancer therapy: Smart nanosystem and combination therapy	90
Investigating the crucial roles of aliphatic tails in disulfide bond-linked docetaxel prodrug nanoassemblies	82
The utility of endogenous glycochenodeoxycholate-3-sulfate and 4β-hydroxycholesterol to evaluate the hepatic disposition of atorvastatin in rats	77
Carrier-free prodrug nanoparticles based on dasatinib and cisplatin for efficient antitumor in vivo	73
Aspects of high-performance and bio-acceptable magnetic nanoparticles for biomedical application	68
A practical strategy to subcutaneous administered in-situ gelling co-delivery system of arsenic and retinoic acid for the treatment of acute promyelocytic leukemia	67
Amphiphilic small molecular mates match hydrophobic drugs to form nanoassemblies based on drug-mate strategy	64
Calcium ion nanomodulators for mitochondria-targeted multimodal cancer therapy	63
Macrophage membrane-mediated targeted drug delivery for treatment of spinal cord injury regardless of the macrophage polarization states	63
Spatiotemporal transformable nano-assembly for on-demand drug delivery to enhance anti-tumor immunotherapy	55
Targeted hyperalkalization with NaOH-loaded starch implants enhances doxorubicin efficacy in tumor treatment	45
Ionic liquids as the effective technology for enhancing transdermal drug delivery: Design principles, roles, mechanisms, and future challenges	44
CaCO3-encircled hollow CuS nanovehicles to suppress cervical cancer through enhanced calcium overload-triggered mitochondria damage	42
Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury	41
Versatile applications of deep eutectic solvents in drug discovery and drug delivery systems: Perspectives and opportunities	41
Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy	40
Water-responsive gel extends drug retention and facilitates skin penetration for curcumin topical delivery against psoriasis	37
Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment	36
In situ injectable hydrogel encapsulating Mn/NO-based immune nano-activator for prevention of postoperative tumor recurrence	35
Nano-enabled agglomerates and compact: Design aspects of challenges	34

Multifunctional self-delivery micelles targeting the invasion-metastasis cascade for enhanced chemotherapy against melanoma and the lung metastasis	34
Doxorubicin hydrochloride and L-arginine co-loaded nanovesicle for drug resistance reversal stimulated by near-infrared light	33
Fine-tuning the activation behaviors of ternary modular cabazitaxel prodrugs for efficient and on-target oral anti-cancer therapy	33
KCNJ15 deficiency promotes drug resistance via affecting the function of lysosomes	32
All-stage targeted nanodiscs for glioma treatment by inducing cuproptosis and apoptosis of cancer cells and cancer stem cells	32
The emerging potential of siRNA nanotherapeutics in treatment of arthritis	31
Recent advances in copper homeostasis-involved tumor theranostics	31
Exosomes: Emerging implementation of nanotechnology for detecting and managing novel corona virus- SARS-CoV-2	29
Regulatory role of long non coding RNAs (lncRNAs) in neurological disorders: From novel biomarkers to promising therapeutic strategies	29
Ferroptosis-based nano delivery systems targeted therapy for colorectal cancer: Insights and future perspectives	28
Effect of the structure of ginsenosides on the in vivo fate of their liposomes	28
Synthetic anti-angiogenic genomic therapeutics for treatment of neovascular age-related macular degeneration	27
Advances in nanotechnology for the diagnosis and management of metabolic dysfunction-associated steatotic liver disease	27
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug	26
Application of chitosan-based nanoparticles in skin wound healing	26
Exosomes in cancer immunoediting and immunotherapy	26
Lipid nanoparticle-mediated CRISPR/Cas9 gene editing and metabolic engineering for anticancer immunotherapy	26
Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs	25
Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis	25
Design, preparation and pharmacodynamics of ICG-Fe(Ⅲ) based HCPT nanocrystals against cancer	25
Implantation of hydrogel-liposome nanoplatform inhibits glioblastoma relapse by inducing ferroptosis	25
Liposome cocktail activator modulates hepatocytes and remodels the microenvironment to mitigate acute liver failure	24
Hyaluronic acid conjugates with controlled oleic acid substitution as new nanomaterials for improving ocular co-delivery of cyclosporine A and oleic acid	23
Nanotechnologies meeting natural sources: Engineered lipoproteins for precise brain disease theranostics	22
Biofunctional supramolecular injectable hydrogel with spongy-like metal-organic coordination for effective repair of critical-sized calvarial defects	22
Nucleobase-crosslinked poly(2-oxazoline) nanoparticles as paclitaxel carriers with enhanced stability and ultra-high drug loading capacity for breast cancer therapy	21
pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma	21
Targeting the resolution pathway of inflammation using Ac2–26 peptide-loaded PEGylated lipid nanoparticles for the remission of rheumatoid arthritis	21
Mimicking natural cholesterol assimilation to elevate the oral delivery of liraglutide for type II diabetes therapy	21
Development of nanoscale drug delivery systems of dihydroartemisinin for cancer therapy: A review	20
Relaxin-encapsulated polymeric metformin nanoparticles remodel tumor immune microenvironment by reducing CAFs for efficient triple-negative breast cancer immunotherapy	20
Enhancing Temozolomide In Vivo Stability and Efficacy Through Hybrid Nanoconjugate Approach for Improved Glioblastoma Multiforme Treatment	20
Advancing ophthalmic delivery of flurbiprofen via synergistic chiral resolution and ion-pairing strategies	19
Sequentially releasing self-healing hydrogel fabricated with TGFβ3-microspheres and bFGF to facilitate rat alveolar bone defect repair	18
A PET probe targeting polyamine transport system for precise tumor diagnosis and therapy	18
Tumor microenvironment reprogramming by nanomedicine to enhance the effect of tumor immunotherapy	18
Stem cell-based ischemic stroke therapy: Novel modifications and clinical challenges	17
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection	17
Protein corona mediated liposomal drug delivery for bacterial infection management	17
Metal ions-bridged J-aggregation mediated nanoassembly composition for breast cancer phototherapy	17
Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis	16
Local dose-dense chemotherapy for triple-negative breast cancer via minimally invasive implantation of 3D printed devices	16
Cell membrane-coated mRNA nanoparticles for enhanced delivery to dendritic cells and immunotherapy	15
Corrugated surface microparticles with chitosan and levofloxacin for improved aerodynamic performance	15
Revamping anti-cGAS-STING therapy via an injectable thermo-responsive supramolecular hydrogel for pathological retinal angiogenesis	15
Improving treatment for Parkinson's disease: Harnessing photothermal and phagocytosis-driven delivery of levodopa nanocarriers across the blood-brain barrier	15
Correction to “Folic acid-conjugated liposomal vincristine for multidrug resistant cancer therapy”	15
Biomimetic biomineralization nanoplatform-mediated differentiation therapy and phototherapy for cancer stem cell inhibition and antitumor immunity activation	14
Insights into microscopic fabrication, macroscopic forms and biomedical applications of alginate composite gel containing metal-organic frameworks	14
Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy	14

CRISPR/Cas9 systems: Delivery technologies and biomedical applications	13
A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy	13
Hydrogen sulfide responsive nanoplatforms: Novel gas responsive drug delivery carriers for biomedical applications	13
Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment	13
Albumin nanoassembly bi-directionally manipulated ferroptosis in tumor and CD8+ T cells for triple-negative breast cancer therapy	13
Naringenin nanocrystals for improving anti-rheumatoid arthritis activity	13
Nanomedicine potentiates mild photothermal therapy for tumor ablation	12
Impact of the amount of PEG on prodrug nanoassemblies for efficient cancer therapy	12
Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies	12
Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders	12
Additive manufacturing of sustainable biomaterials for biomedical applications	11
Innovative strategies for photodynamic therapy against hypoxic tumor	11
Tumor microenvironment-responsive artesunate loaded Z-scheme heterostructures for synergistic photo-chemodynamic therapy of hypoxic tumor	11
Dual-responsive nanovaccine for cytosolic delivery of antigens to boost cellular immune responses and cancer immunotherapy	10
Enhanced lymphatic transportation of SLN by mimicking oligopeptide transportation route	10
CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia	10
CeO2 Nanozyme-Embedded Thermal-Deformative Polymer for Site-Specific Chemotherapy via HIF-1α-P-gp/Lipolysis Axis Reversal	10
Amphotericin B release rate is the link between drug status in the liposomal bilayer and toxicity	10
Roles of effective stabilizers in improving oral bioavailability of naringenin nanocrystals: Maintenance of supersaturation generated upon dissolution by inhibition of drug dimerization	10
Targeted degradation of LRG1 to attenuate renal fibrosis	10
Functionalized chitosan as nano-delivery platform for CRISPR-Cas9 in cancer treatment	10
Innovative color jet 3D printing of levetiracetam personalized paediatric preparations	9
A double-edged sword: ROS related therapies in the treatment of psoriasis	9
Targeting the organelle for radiosensitization in cancer radiotherapy	9
Exosomes-mediated tumor treatment: One body plays multiple roles	9
Structure based release kinetics analysis of doxazosin mesylate sustained-release tablets using micro-computed tomography	8
Role of the cation-chloride-cotransporters in the circadian system	8
pH-sensitive micelles self-assembled from star-shaped TPGS copolymers with ortho ester linkages for enhanced MDR reversal and chemotherapy	8
Porous PLGA microspheres for the inhalation delivery of icariin and miR-23b in the treatment of metastatic lung cancer	8
Biopharmaceutical and pharmacokinetic attributes to drive nanoformulations of small molecule tyrosine kinase inhibitors	8
Linear-like polypeptide-based micelle with pH-sensitive detachable PEG to deliver dimeric camptothecin for cancer therapy	8
Synergistic chemotherapy/PTT/oxygen enrichment by multifunctional liposomal polydopamine nanoparticles for rheumatoid arthritis treatment	8
A novel fixed-combination timolol-netarsudil-latanoprost ophthalmic solution for the treatment of glaucoma and ocular hypertension	8
Advances of mRNA vaccines for COVID-19: A new prophylactic revolution begins	8
Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128-3p agomir and Oroxin B: A novel drug delivery approach based on PI3K-AKT and VEGF pathway crosstalk	7
Implantable devices for resected glioblastoma therapy	7
Monitoring the in vivo siRNA release from lipid nanoparticles based on the fluorescence resonance energy transfer principle	7
MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation	7
Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems	7
Delivery strategies for CRISPR/Cas genome editing tool for retinal dystrophies: challenges and opportunities	7
Recent advances in living cell nucleic acid probes based on nanomaterials for early cancer diagnosis	7
Antibiotic-based small molecular micelles combined with photodynamic therapy for bacterial infections	7
Extracellular vesicles for delivering therapeutic agents in ischemia/reperfusion injury	7
Exosome-membrane and polymer-based hybrid-complex for systemic delivery of plasmid DNA into brains for the treatment of glioblastoma	7
From mesenchymal stem cells to their extracellular vesicles: Progress and prospects for asthma therapy	7
Zinc-doped Prussian blue nanoparticles for mutp53-carrying tumor ion interference and photothermal therapy	7
Glucocorticoids-based prodrug design: Current strategies and research progress	7
Single-dose oral administration of drug-loaded magnetic 3D-printed microbullets for eradication of Helicobacter pylori	6
Targeted anti-cancer therapy: Co-delivery of VEGF siRNA and Phenethyl isothiocyanate (PEITC) via cRGD-modified lipid nanoparticles for enhanced anti-angiogenic efficacy	6
Recent advances on thermosensitive hydrogels-mediated precision therapy	6
Overcoming the cellular barriers and beyond: Recent progress on cell penetrating peptide modified nanomedicine in combating physiological and pathological barriers	6
New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus	6
The enantioselective enhancing effect and mechanistic insights of chiral enhancers in transdermal drug delivery	6
Navigating the brain: Harnessing endogenous cellular hitchhiking for targeting neoplastic and neuroinflammatory diseases	6
IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity	6
Integrated computer-aided formulation design: A case study of andrographolide/ cyclodextrin ternary formulation	6
Antibacterial biomaterials for skin wound dressing	5
Oncolytic virus-based hepatocellular carcinoma treatment: Current status, intravenous delivery strategies, and emerging combination therapeutic solutions	5
mRNA vaccines: Past, present, future	5
Multifunctional Prussian Blue Nanoparticles loading with Xuetongsu for efficient Rheumatoid Arthritis therapy through targeting inflammatory Macrophages and Osteoclasts	5
Fenton metal nanomedicines for imaging-guided combinatorial chemodynamic therapy against cancer	5
Blockade of neutrophil recruitment to tumor sites based on sialic acid-modified nanoplatforms enhances the efficacy of checkpoint blockade immunotherapy	5
Advances in photosensitizer-related design for photodynamic therapy	5
Platelet-derived microparticles and their cargos: The past, present and future	5
Osteoimmunity-regulating biomaterials promote bone regeneration	5