OOIR: Observatory of International Research

Papers

(The median citation count of Asian Journal of Pharmaceutical Sciences is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Artificial polysaccharide-binding protein mediates co-assembly of nanodrug and probiotics against drug-resistant infectious enteritis	153
Ginseng-derived exosome-like nanovesicles protect against liver fibrosis by regulating TIMP2 pathways and gut dysbiosis	100
Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment	87
CaCO3-encircled hollow CuS nanovehicles to suppress cervical cancer through enhanced calcium overload-triggered mitochondria damage	74
Spatiotemporal transformable nano-assembly for on-demand drug delivery to enhance anti-tumor immunotherapy	53
Recent advances in cell membrane-based biomimetic delivery systems for Parkinson’s disease: Perspectives and challenges	48
Versatile applications of deep eutectic solvents in drug discovery and drug delivery systems: Perspectives and opportunities	36
Charge adaptive phytochemical-based nanoparticles for eradication of methicillin-resistant staphylococcus aureus biofilms	36
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection	33
Penetrative biomimetic nanovehicle boosts immunotherapy in triple-negative breast cancer via SOS1 blockade	33
Hyaluronic acid conjugates with controlled oleic acid substitution as new nanomaterials for improving ocular co-delivery of cyclosporine A and oleic acid	33
Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment	31
Cell membrane-coated mRNA nanoparticles for enhanced delivery to dendritic cells and immunotherapy	29
Improving treatment for Parkinson's disease: Harnessing photothermal and phagocytosis-driven delivery of levodopa nanocarriers across the blood-brain barrier	28
Structure based release kinetics analysis of doxazosin mesylate sustained-release tablets using micro-computed tomography	27
Targeted delivery of glucocerebrosidase to lysosomes: The LYSOTAC (LYSOsome-TArgeting Chimera) technology	27
pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma	27
Publisher's Note	24
Development and preclinical evaluation of a novel FGFR3-targeted antibody-drug conjugate in bladder cancer	24
Comparison of virus-capsid mimicking biologic-shell based versus polymeric-shell nanoparticles for enhanced oral insulin delivery	24
Blockade of neutrophil recruitment to tumor sites based on sialic acid-modified nanoplatforms enhances the efficacy of checkpoint blockade immunotherapy	23
Advanced strategies of covalent organic framework nanomedicines in targeting and overcoming biological barriers	23
Electrically conductive “SMART” hydrogels for on-demand drug delivery	22
Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases	22
Immunotherapeutic hydrogel for co-delivery of STAT3 siRNA liposomes and lidocaine hydrochloride for postoperative comprehensive management of NSCLC in a single application	22

Preliminary delivery efficiency prediction of nanotherapeutics into crucial cell populations in bone marrow niche	22
Neutrophil-targeted liposomal platform: A shift in novel approach for early detection and treatment of cancer metastasis	22
Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin	22
Enhancing chemoimmunotherapy for colorectal cancer with paclitaxel and alantolactone via CD44-Targeted nanoparticles: A STAT3 signaling pathway modulation approach	21
Nanoparticle-mediated synergistic anticancer effect of ferroptosis and photodynamic therapy: Novel insights and perspectives	21
Nanomaterials: An innovative integrative paradigm for hepatocellular carcinoma adjuvant treatment	19
High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis	19
Amphiphilic lipid-peptide engineered placenta-derived mesenchymal stem cells for liver fibrosis treatment	19
Unraveling the complex role of intestinal microbiota in drug permeability: Insights from N-acetylcysteine	18
Bispecific antibody vesicles: A multifunctional bioactive drug delivery platform for the treatment of Pseudomonas aeruginosa infection	18
Intravitreal long-term sustained ranibizumab delivery using injectable microgel-embedded hydrogel	18
Vat-based photopolymerization 3D printing: From materials to topical and transdermal applications	18
A self-assembled nano-spray formulation for synergistic therapy of anti-inflammation and skin repair	17
Inhalable stem cell-derived artificial nanovesicles for targeted siRNA delivery to effectively alleviate asthma symptoms	17
Targeted hyperalkalization with NaOH-loaded starch implants enhances doxorubicin efficacy in tumor treatment	17
Insights on drug and gene delivery systems in liver fibrosis	17
Ionic liquids as the effective technology for enhancing transdermal drug delivery: Design principles, roles, mechanisms, and future challenges	16
A programmable nanoreactor for photothermal immunotherapy via NIR-II triggered enzyme-catalyzed immunogenic tumor microenvironment remodeling	16
A Drug-Repurposing Nanotheranostic for Synergistic Management of Resistant Bacterial Pneumonia	16
Microneedle technology in the treatment of ocular diseases: Advances and applications	16
Recent progress of ferroptosis in cancers and drug discovery	16
An exosome-inspired docetaxel prodrug nanoplatform for potent STING activation and synergistic chemoimmunotherapy	16
Mimicking natural cholesterol assimilation to elevate the oral delivery of liraglutide for type II diabetes therapy	15
Overcoming corneal barriers: Posaconazole loaded cationic surfactant vesicles for enhanced ocular permeability and anti-fungal efficacy	15
Relaxin-encapsulated polymeric metformin nanoparticles remodel tumor immune microenvironment by reducing CAFs for efficient triple-negative breast cancer immunotherapy	14
Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis	14
Bioengineered milk-derived extracellular vesicles implementing high drug loading and membrane integrity for efficient oral drug delivery	14
Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems	13
Additive manufacturing of sustainable biomaterials for biomedical applications	13
Synergistic chemotherapy/PTT/oxygen enrichment by multifunctional liposomal polydopamine nanoparticles for rheumatoid arthritis treatment	13
Monitoring the in vivo siRNA release from lipid nanoparticles based on the fluorescence resonance energy transfer principle	13
Design strategies, advances and future perspectives of colon-targeted delivery systems for the treatment of inflammatory bowel disease	12
Functionalized chitosan as nano-delivery platform for CRISPR-Cas9 in cancer treatment	12
Treatment of colorectal cancer by anticancer and antibacterial effects of hemiprotonic phenanthroline-phenanthroline+ with nanomicelle delivery	12
Red ginseng-derived nanovesicles to modulate osteoblast and osteoclastogenesis for osteoporosis therapy	12
Hypoxia-responsive hybrid nanoparticles loaded with fingolimod and colistin against multidrug-resistant Klebsiella pneumoniae with mature biofilm	12
A novel fixed-combination timolol-netarsudil-latanoprost ophthalmic solution for the treatment of glaucoma and ocular hypertension	12
Advances in the development of amorphous solid dispersions: The role of polymeric carriers	11
Endosomal disruption by co-encapsulating gentamicin in lipid nanoparticles for efficient siRNA delivery and cancer therapy	11
“NIR-triggered ROS storage” photodynamic intraocular implant for high-efficient and safe posterior capsular opacification prevention	11
A biomimetic spore nanoplatform for boosting chemodynamic therapy and bacteria-mediated antitumor immunity for synergistic cancer treatment	11
Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition: Harnessing the power of nanotheranostics	10
Advanced drug delivery platforms target cancer stem cells	10
Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease	10
Freezing shock monocytes deliver antisense oligonucleotides via liposomes for the treatment of idiopathic pulmonary fibrosis	10
Design of pH-responsive antimicrobial peptide melittin analog-camptothecin conjugates for tumor therapy	10
Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury	10
Microneedle Vaccine Printer Enables Decentralized and Thermostable mRNA Vaccine Delivery	10
Dual-functional self-assembled nanosystems with enhanced protease resistance: Promoting bacterial aggregation and immune activation for multidrug-resistant bacterial infection	10
Lignin-assisted construction of sub-10 nm supramolecular self-assembly for photothermal immunotherapy and potentiating anti-PD-1 therapy against primary and distant breast tumors	10

Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider	10
All-stage targeted nanodiscs for glioma treatment by inducing cuproptosis and apoptosis of cancer cells and cancer stem cells	9
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug	9
Oral probiotic delivery-based therapeutic strategies for inflammatory bowel disease	9
EVs-mediated delivery of CB2 receptor agonist for Alzheimer's disease therapy	9
Advances in nanotechnology for the diagnosis and management of metabolic dysfunction-associated steatotic liver disease	9
Protein corona mediated liposomal drug delivery for bacterial infection management	8
Controlled release of berberine modulates the wound microbiome to accelerate wound healing	8
Revamping anti-cGAS-STING therapy via an injectable thermo-responsive supramolecular hydrogel for pathological retinal angiogenesis	8
Advances in nanotechnology for the diagnosis and management of autoimmune diseases	8
CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia	8
Exosome-membrane and polymer-based hybrid-complex for systemic delivery of plasmid DNA into brains for the treatment of glioblastoma	8
Synergistic antimicrobial nanocomposite: Protamine-loaded PVP-capped silver nanoparticles for combating multidrug-resistant infections	8
Implantation of hydrogel-liposome nanoplatform inhibits glioblastoma relapse by inducing ferroptosis	8
Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy	8
Insights into microscopic fabrication, macroscopic forms and biomedical applications of alginate composite gel containing metal-organic frameworks	8
Single-dose oral administration of drug-loaded magnetic 3D-printed microbullets for eradication of Helicobacter pylori	8
IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity	8
Targeting macrophages in OA nanomedicine: Therapeutic opportunity or delivery delusion? A pragmatic reappraisal	8
Nanotechnologies meeting natural sources: Engineered lipoproteins for precise brain disease theranostics	8
Hydrogel Co-delivery of 5-Fluorouracil and siRNA Attenuates TGF-β1-Mediated MMT to Prevent Postoperative Peritoneal Metastasis and Adhesion in Colorectal Cancer	8
Metal-organic frameworks as therapeutic chameleons: revolutionizing the cancer therapy employing novel nanoarchitectonics	8
Extracellular vesicles in cancer immunotherapy: Therapeutic, challenges and clinical progress	7
Next generation of neurological therapeutics: Native and bioengineered extracellular vesicles derived from stem cells	7
MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation	7
Advances in nano-delivery systems for overcoming the challenges of applying siRNA drugs in tumor therapy	7
Exploring the frontier of oral nanomedicine in colorectal cancer therapy: Folate-targeted 5FU-Nisin-Selenium conjugates and probiotic-rich diets as a novel approach	7
Osteoimmunity-regulating biomaterials promote bone regeneration	7
Roles of effective stabilizers in improving oral bioavailability of naringenin nanocrystals: Maintenance of supersaturation generated upon dissolution by inhibition of drug dimerization	7
Engineered exosomes-based theranostic strategy for tumor metastasis and recurrence	7
Polydopamine-coated i-motif DNA/Gold nanoplatforms for synergistic photothermal-chemotherapy	7
Light-stimulated smart thermo-responsive constructs for enhanced wound healing: A streamlined command approach	7
Celastrol-loaded metal-phenolic nanozymes integrated microneedles with ROS scavenging and anti-inflammatory activities for psoriasis treatment	7
Targeted degradation of LRG1 to attenuate renal fibrosis	7
In vivo self-assembled siRNAs targeting VEGFR2 and mTOR for renal cell carcinoma treatment	6
Leveraging immunoliposomes as nanocarriers against SARS-CoV-2 and its emerging variants	6
Phytoestrogen-derived multifunctional ligands for targeted therapy of breast cancer	6
Reversing ferroptosis resistance by MOFs through regulation intracellular redox homeostasis	6
Codelivery of apigenin, FdUMP and CD276 antibody synergistic inhibit colorectal cancer by ferroptosis-apoptosis-pyroptosis and CD276 blockade	6
Recent advances in spatio-temporally controllable systems for management of glioma	6
Small extracellular vesicles encapsulating lefty1 mRNA inhibit hepatic fibrosis	6
Functionalized lipid nanoparticles modulate the blood-brain barrier and eliminate α-synuclein to repair dopamine neurons	6
Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy	5
Liposome cocktail activator modulates hepatocytes and remodels the microenvironment to mitigate acute liver failure	5
Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury	5
Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs	5
Biofunctional supramolecular injectable hydrogel with spongy-like metal-organic coordination for effective repair of critical-sized calvarial defects	5
Traditional Chinese medicine ingredients integrated microneedles: A promising strategy for transdermal treatment	5
Targeted protein degradation with small molecules for cancer immunotherapy	5
Small molecular chelator for comprehensive regulation of tumor lactate levels in synergy with photodynamic therapy for cancer treatment	5
In situ injectable hydrogel encapsulating Mn/NO-based immune nano-activator for prevention of postoperative tumor recurrence	5
Biomimetic nanoparticles co-deliver hirudin and lumbrukinase to ameliorate thrombus and inflammation for atherosclerosis therapy	5
Local dose-dense chemotherapy for triple-negative breast cancer via minimally invasive implantation of 3D printed devices	5
Advancing ophthalmic delivery of flurbiprofen via synergistic chiral resolution and ion-pairing strategies	5
Mesoporous polydopamine nanoplatform enhances IL-2 immunotherapy for hepatocellular carcinoma via mild photothermal therapy and lactate regulation	5
Doxorubicin hydrochloride and L-arginine co-loaded nanovesicle for drug resistance reversal stimulated by near-infrared light	5
Fine-tuning the activation behaviors of ternary modular cabazitaxel prodrugs for efficient and on-target oral anti-cancer therapy	5
An opposite pH-responsiveness “gating” strategy: Intelligent sporopollenin exine armor for targeted therapy of colitis	5
Lipid nanoparticle-mediated CRISPR/Cas9 gene editing and metabolic engineering for anticancer immunotherapy	5
Biomimetic biomineralization nanoplatform-mediated differentiation therapy and phototherapy for cancer stem cell inhibition and antitumor immunity activation	5
Photothermal-detonated functional macrophage membrane-camouflaged nano-crackers induce tumor cell wandering-anoikis	5
Stem cell-based ischemic stroke therapy: Novel modifications and clinical challenges	5