OOIR: Observatory of International Research

Papers

(The median citation count of Asian Journal of Pharmaceutical Sciences is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Recent advances in cell membrane-based biomimetic delivery systems for Parkinson’s disease: Perspectives and challenges	301
Versatile applications of deep eutectic solvents in drug discovery and drug delivery systems: Perspectives and opportunities	140
Application of chitosan-based nanoparticles in skin wound healing	110
Liposomes and liposome-like nanoparticles: From anti-fungal infection to the COVID-19 pandemic treatment	98
Artificial polysaccharide-binding protein mediates co-assembly of nanodrug and probiotics against drug-resistant infectious enteritis	75
Spatiotemporal transformable nano-assembly for on-demand drug delivery to enhance anti-tumor immunotherapy	65
CaCO3-encircled hollow CuS nanovehicles to suppress cervical cancer through enhanced calcium overload-triggered mitochondria damage	58
Charge adaptive phytochemical-based nanoparticles for eradication of methicillin-resistant staphylococcus aureus biofilms	50
Ginseng-derived exosome-like nanovesicles protect against liver fibrosis by regulating TIMP2 pathways and gut dysbiosis	50
Hyaluronic acid conjugates with controlled oleic acid substitution as new nanomaterials for improving ocular co-delivery of cyclosporine A and oleic acid	45
Bone mesenchymal stem cell-derived exosomes involved co-delivery and synergism effect with icariin via mussel-inspired multifunctional hydrogel for cartilage protection	35
pH-activatable oxidative stress amplifying dissolving microneedles for combined chemo-photodynamic therapy of melanoma	34
Improving treatment for Parkinson's disease: Harnessing photothermal and phagocytosis-driven delivery of levodopa nanocarriers across the blood-brain barrier	33
Penetrative biomimetic nanovehicle boosts immunotherapy in triple-negative breast cancer via SOS1 blockade	32
Development and preclinical evaluation of a novel FGFR3-targeted antibody-drug conjugate in bladder cancer	30
Cell membrane-coated mRNA nanoparticles for enhanced delivery to dendritic cells and immunotherapy	30
Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment	30
Structure based release kinetics analysis of doxazosin mesylate sustained-release tablets using micro-computed tomography	26
Publisher's Note	26
Targeted delivery of glucocerebrosidase to lysosomes: The LYSOTAC (LYSOsome-TArgeting Chimera) technology	26
mRNA vaccines: Past, present, future	25
Blockade of neutrophil recruitment to tumor sites based on sialic acid-modified nanoplatforms enhances the efficacy of checkpoint blockade immunotherapy	24
Preliminary delivery efficiency prediction of nanotherapeutics into crucial cell populations in bone marrow niche	24
Advanced strategies of covalent organic framework nanomedicines in targeting and overcoming biological barriers	24
Comparison of virus-capsid mimicking biologic-shell based versus polymeric-shell nanoparticles for enhanced oral insulin delivery	24

Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin	23
Nanomaterials: An Innovative Integrative Paradigm for Hepatocellular Carcinoma Adjuvant Treatment	23
Enhancing chemoimmunotherapy for colorectal cancer with paclitaxel and alantolactone via CD44-Targeted nanoparticles: A STAT3 signaling pathway modulation approach	23
Electrically conductive “SMART” hydrogels for on-demand drug delivery	23
Immunotherapeutic hydrogel for co-delivery of STAT3 siRNA liposomes and lidocaine hydrochloride for postoperative comprehensive management of NSCLC in a single application	22
Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases	21
Neutrophil-targeted liposomal platform: A shift in novel approach for early detection and treatment of cancer metastasis	21
Nanoparticle-mediated synergistic anticancer effect of ferroptosis and photodynamic therapy: Novel insights and perspectives	21
Amphiphilic lipid-peptide engineered placenta-derived mesenchymal stem cells for liver fibrosis treatment	20
Vat-based photopolymerization 3D printing: From materials to topical and transdermal applications	20
High drug loading hydrophobic cross-linked dextran microspheres as novel drug delivery systems for the treatment of osteoarthritis	20
Targeted hyperalkalization with NaOH-loaded starch implants enhances doxorubicin efficacy in tumor treatment	18
Intravitreal long-term sustained ranibizumab delivery using injectable microgel-embedded hydrogel	18
A self-assembled nano-spray formulation for synergistic therapy of anti-inflammation and skin repair	18
Microneedle technology in the treatment of ocular diseases: Advances and applications	17
An exosome-inspired docetaxel prodrug nanoplatform for potent STING activation and synergistic chemoimmunotherapy	17
Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis	17
Insights on drug and gene delivery systems in liver fibrosis	16
Mimicking natural cholesterol assimilation to elevate the oral delivery of liraglutide for type II diabetes therapy	16
Recent progress of ferroptosis in cancers and drug discovery	16
Additive manufacturing of sustainable biomaterials for biomedical applications	16
Ionic liquids as the effective technology for enhancing transdermal drug delivery: Design principles, roles, mechanisms, and future challenges	16
A programmable nanoreactor for photothermal immunotherapy via NIR-II triggered enzyme-catalyzed immunogenic tumor microenvironment remodeling	16
Bioengineered milk-derived extracellular vesicles implementing high drug loading and membrane integrity for efficient oral drug delivery	15
Overcoming corneal barriers: Posaconazole loaded cationic surfactant vesicles for enhanced ocular permeability and anti-fungal efficacy	15
Relaxin-encapsulated polymeric metformin nanoparticles remodel tumor immune microenvironment by reducing CAFs for efficient triple-negative breast cancer immunotherapy	15
Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis	15
Hair follicle-targeting drug delivery strategies for the management of hair follicle-associated disorders	15
Correction to “Folic acid-conjugated liposomal vincristine for multidrug resistant cancer therapy”	15
Functionalized chitosan as nano-delivery platform for CRISPR-Cas9 in cancer treatment	14
A novel fixed-combination timolol-netarsudil-latanoprost ophthalmic solution for the treatment of glaucoma and ocular hypertension	14
Monitoring the in vivo siRNA release from lipid nanoparticles based on the fluorescence resonance energy transfer principle	14
Hydroxyethyl starch conjugates co-assembled nanoparticles promote photodynamic therapy and antitumor immunity by inhibiting antioxidant systems	14
Synergistic chemotherapy/PTT/oxygen enrichment by multifunctional liposomal polydopamine nanoparticles for rheumatoid arthritis treatment	13
Treatment of colorectal cancer by anticancer and antibacterial effects of hemiprotonic phenanthroline-phenanthroline+ with nanomicelle delivery	13
Endosomal disruption by co-encapsulating gentamicin in lipid nanoparticles for efficient siRNA delivery and cancer therapy	13
Antibacterial biomaterials for skin wound dressing	13
Hypoxia-responsive hybrid nanoparticles loaded with fingolimod and colistin against multidrug-resistant Klebsiella pneumoniae with mature biofilm	13
Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury	12
Advances in the development of amorphous solid dispersions: The role of polymeric carriers	12
Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider	12
Rational fusion design inspired by cell-penetrating peptide: SS31/S-14 G Humanin hybrid peptide with amplified multimodal efficacy and bio-permeability for the treatment of Alzheimer's disease	12
Lignin-assisted construction of sub-10 nm supramolecular self-assembly for photothermal immunotherapy and potentiating anti-PD-1 therapy against primary and distant breast tumors	12
Advanced drug delivery platforms target cancer stem cells	12
Design strategies, advances and future perspectives of colon-targeted delivery systems for the treatment of inflammatory bowel disease	12
A biomimetic spore nanoplatform for boosting chemodynamic therapy and bacteria-mediated antitumor immunity for synergistic cancer treatment	12
Design of pH-responsive antimicrobial peptide melittin analog-camptothecin conjugates for tumor therapy	11
“NIR-triggered ROS storage” photodynamic intraocular implant for high-efficient and safe posterior capsular opacification prevention	11
Dual-functional self-assembled nanosystems with enhanced protease resistance: Promoting bacterial aggregation and immune activation for multidrug-resistant bacterial infection	11
Microneedle Vaccine Printer Enables Decentralized and Thermostable mRNA Vaccine Delivery	11

Non-cytotoxic nanoparticles re-educating macrophages achieving both innate and adaptive immune responses for tumor therapy	11
EVs-mediated delivery of CB2 receptor agonist for Alzheimer's disease therapy	10
Autophagy and mitophagy as potential therapeutic targets in diabetic heart condition: Harnessing the power of nanotheranostics	10
All-stage targeted nanodiscs for glioma treatment by inducing cuproptosis and apoptosis of cancer cells and cancer stem cells	10
Implantation of hydrogel-liposome nanoplatform inhibits glioblastoma relapse by inducing ferroptosis	10
Design, preparation and pharmacodynamics of ICG-Fe(Ⅲ) based HCPT nanocrystals against cancer	10
Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug	10
Insights into microscopic fabrication, macroscopic forms and biomedical applications of alginate composite gel containing metal-organic frameworks	9
Protein corona mediated liposomal drug delivery for bacterial infection management	9
Revamping anti-cGAS-STING therapy via an injectable thermo-responsive supramolecular hydrogel for pathological retinal angiogenesis	9
Nanotechnologies meeting natural sources: Engineered lipoproteins for precise brain disease theranostics	9
Controlled release of berberine modulates the wound microbiome to accelerate wound healing	9
Pulmonary delivery of mucus-traversing PF127-modified silk fibroin nanoparticles loading with quercetin for lung cancer therapy	9
Advances in nanotechnology for the diagnosis and management of metabolic dysfunction-associated steatotic liver disease	9
MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation	8
Targeted degradation of LRG1 to attenuate renal fibrosis	8
Roles of effective stabilizers in improving oral bioavailability of naringenin nanocrystals: Maintenance of supersaturation generated upon dissolution by inhibition of drug dimerization	8
New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus	8
Exosome-membrane and polymer-based hybrid-complex for systemic delivery of plasmid DNA into brains for the treatment of glioblastoma	8
Advances in nanotechnology for the diagnosis and management of autoimmune diseases	8
Amphotericin B release rate is the link between drug status in the liposomal bilayer and toxicity	8
Single-dose oral administration of drug-loaded magnetic 3D-printed microbullets for eradication of Helicobacter pylori	8
Extracellular vesicles in cancer immunotherapy: Therapeutic, challenges and clinical progress	8
CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia	8
Metal-organic frameworks as therapeutic chameleons: revolutionizing the cancer therapy employing novel nanoarchitectonics	8
IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity	8
Next generation of neurological therapeutics: Native and bioengineered extracellular vesicles derived from stem cells	8
Exploring the frontier of oral nanomedicine in colorectal cancer therapy: Folate-targeted 5FU-Nisin-Selenium conjugates and probiotic-rich diets as a novel approach	7
Celastrol-loaded metal-phenolic nanozymes integrated microneedles with ROS scavenging and anti-inflammatory activities for psoriasis treatment	7
Small extracellular vesicles encapsulating lefty1 mRNA inhibit hepatic fibrosis	7
Polydopamine-coated i-motif DNA/Gold nanoplatforms for synergistic photothermal-chemotherapy	7
Codelivery of apigenin, FdUMP and CD276 antibody synergistic inhibit colorectal cancer by ferroptosis-apoptosis-pyroptosis and CD276 blockade	7
Gp350-anchored extracellular vesicles: promising vehicles for delivering therapeutic drugs of B cell malignancies	7
Engineered exosomes-based theranostic strategy for tumor metastasis and recurrence	7
Osteoimmunity-regulating biomaterials promote bone regeneration	7
Reversing ferroptosis resistance by MOFs through regulation intracellular redox homeostasis	7
Light-stimulated smart thermo-responsive constructs for enhanced wound healing: A streamlined command approach	7
Functionalized lipid nanoparticles modulate the blood-brain barrier and eliminate α-synuclein to repair dopamine neurons	6
Recent advances in spatio-temporally controllable systems for management of glioma	6
Doxorubicin hydrochloride and L-arginine co-loaded nanovesicle for drug resistance reversal stimulated by near-infrared light	6
Leveraging immunoliposomes as nanocarriers against SARS-CoV-2 and its emerging variants	6
In situ injectable hydrogel encapsulating Mn/NO-based immune nano-activator for prevention of postoperative tumor recurrence	6
Elaborately engineering of a dual-drug co-assembled nanomedicine for boosting immunogenic cell death and enhancing triple negative breast cancer treatment	6
Phytoestrogen-derived multifunctional ligands for targeted therapy of breast cancer	6
Small molecular chelator for comprehensive regulation of tumor lactate levels in synergy with photodynamic therapy for cancer treatment	5
Scavenger receptor A-mediated nanoparticles target M1 macrophages for acute liver injury	5
Biofunctional supramolecular injectable hydrogel with spongy-like metal-organic coordination for effective repair of critical-sized calvarial defects	5
Biomimetic nanoparticles co-deliver hirudin and lumbrukinase to ameliorate thrombus and inflammation for atherosclerosis therapy	5
Fine-tuning the activation behaviors of ternary modular cabazitaxel prodrugs for efficient and on-target oral anti-cancer therapy	5
Milk-derived exosomes as a promising vehicle for oral delivery of hydrophilic biomacromolecule drugs	5
Targeted protein degradation with small molecules for cancer immunotherapy	5
Nucleobase-crosslinked poly(2-oxazoline) nanoparticles as paclitaxel carriers with enhanced stability and ultra-high drug loading capacity for breast cancer therapy	5
Albumin nanoassembly bi-directionally manipulated ferroptosis in tumor and CD8+ T cells for triple-negative breast cancer therapy	5
Liposome cocktail activator modulates hepatocytes and remodels the microenvironment to mitigate acute liver failure	5
Dynamic crosslinked polymeric nano-prodrugs for highly selective synergistic chemotherapy	5
Lipid nanoparticle-mediated CRISPR/Cas9 gene editing and metabolic engineering for anticancer immunotherapy	5
Stem cell-based ischemic stroke therapy: Novel modifications and clinical challenges	5
Advancing ophthalmic delivery of flurbiprofen via synergistic chiral resolution and ion-pairing strategies	5