OOIR: Observatory of International Research

Papers

(The H4-Index of Theranostics is 65. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	580
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	226
Noninvasive closed-loop acoustic brain-computer interface for seizure control	223
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	208
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	193
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	186
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	186
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m⁶A/YTHDF1-mediated enhancement on ATG3 stability	179
Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model	178
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	160
Targeted delivery of anti-miRNA21 sensitizes PD-L1^high tumor to immunotherapy by promoting immunogenic cell death	153
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	147
Recent progress of nano-drugs in neutron capture therapy	137
Future opportunities and nuances with the use of PSMA PET in prostate cancer (MD PET 1)	135
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	132
The LMIT: Light-mediated minimally-invasive theranostics in oncology	130
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	130
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	126
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	122
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	120
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation	119
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	116
The emerging role of Piezo1 in the musculoskeletal system and disease	115
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	112
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	106

Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	102
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	101
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	100
Myeloid cell-specific β2-adrenergic receptor deletion improves early cardiac injury resolution via de-repression of Anxa1	97
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	96
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	95
Glucosylceramide regulates depression through activating peroxisome proliferator-activated receptor gamma in dorsal striatum	92
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	92
“Electron transport chain interference” strategy of amplified bacterial ferroptosis and defect-engineered nanozyme for diabetic wound healing	89
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	88
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	87
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	86
Self-boosting targeted anticancer therapy via cancer cell self-reprogramming with GGT-targeting oxidative stress nanoamplifiers	85
Flowerbed-inspired biomimetic 3D-printed scaffolds functionalized with urine-derived stem cell exosomes promote alveolar bone regeneration by regulating energy metabolism	84
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	80
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	80
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	79
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	79
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	77
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	76
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	75
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	74
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	74
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	73
Development of a nanoparticle-based immunotherapy targeting CD137 for nasopharyngeal carcinoma treatment	72
Cell-free secretome of CD56 ^bright CD16 ^bright directly reprogrammed NK cells enhances wound heali	72
First-in-human study of an optimized, potential kit-type, SSTR antagonist ⁶⁸Ga-DATA^5m-LM4 in patients with metastatic neuroendocrine tumors	72
Platelet membrane decorated exosomes enhance targeting efficacy and therapeutic index to alleviate arterial restenosis	72
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	71
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	71
The first abdominal aortic aneurysm organoid model replicates complex microenvironment for in vitro disease study	70
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	70
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	70
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	69
Connective tissue growth factor contributes to resistance to anti-angiogenic therapies in renal cancer	69
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	69
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	68
Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing	67
CBX4 suppresses CD8⁺ T cell antitumor immunity by reprogramming glycolytic metabolism	66
Targeting efferocytosis for tissue regeneration: From microenvironment reprogramming to clinical translation	65
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	65
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	65