Theranostics

Article	Citations
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy	601
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	436
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	369
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	344
The LMIT: Light-mediated minimally-invasive theranostics in oncology	215
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside	212
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	208
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	196
Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism	179
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	162
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	160
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	154
Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity — Introducing High NET Affinity PET Probe 18F-AF78	152
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	151
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	150
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	147
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	144
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model	140
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	139
A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer	139
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage	134
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold	131
High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease	126
Targeted delivery of anti-miRNA21 sensitizes PD-L1high tumor to immunotherapy by promoting immunogenic cell death	125
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	123

GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	122
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	119
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	117
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	116
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability	114
Recent progress of nano-drugs in neutron capture therapy	114
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	112
FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts	105
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	102
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	102
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	98
The emerging role of Piezo1 in the musculoskeletal system and disease	98
5-Aminolevulinate improves metabolic recovery and cell survival of the liver following cold preservation	98
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	97
Noninvasive closed-loop acoustic brain-computer interface for seizure control	96
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	95
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	94
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms	94
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	94
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype	93
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	93
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	91
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	90
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	88
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy	88
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	88
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial: Erratum	86
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	84
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α: Erratum	83
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	83
A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum	83
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	82
Platelet membrane decorated exosomes enhance targeting efficacy and therapeutic index to alleviate arterial restenosis	82
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	81
Kir6.1/K-ATP channel in astrocytes is an essential negative modulator of astrocytic pyroptosis in mouse model of depression	81
TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response	80
Identification of early invisible acute ischemic stroke in non-contrast computed tomography using two-stage deep-learning model	79
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	78
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	78
First-in-human study of an optimized, potential kit-type, SSTR antagonist 68Ga-DATA5m-LM4 in patients with metastatic neuroendocrine tumors	77
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration	76
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication	76
Unlocking the dual role of LSD1 in tumor immunity: innate and adaptive pathways	76
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	74
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	73
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	73
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease	72
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	72
NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice	72
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	71

CBX4 suppresses CD8+ T cell antitumor immunity by reprogramming glycolytic metabolism	71
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	70
TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy	70
Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury	70
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	69
Supercharging CAR-T cells through transcriptional and epigenetic armoring	69
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	69
Re-engineering the inner surface of ferritin nanocage enables dual drug payloads for synergistic tumor therapy	68
Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing	67
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	66
Optic chiasmatic potential by endoscopically implanted skull base microinvasive biosensor: a brain-machine interface approach for anterior visual pathway assessment	66
Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development	66
Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation	65
Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases	65
Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization	65
Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-β species	65
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis	64
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	64
Wound microenvironment-responsive glucose consumption and hydrogen peroxide generation synergistic with azithromycin for diabetic wounds healing	64
SERS Tags for Biomedical Detection and Bioimaging	63
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	63
How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?	63
The role of lipid metabolic reprogramming in tumor microenvironment	62
Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis	62
High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo Magnetic Particle Imaging	61
Cathelicidin-related antimicrobial peptide protects against enteric pathogen-accelerated type 1 diabetes in mice	61
Noninvasive DWI tracking of hiPSCs differentiation into RTECs in AKI recovery via the KSP promoter-mediated AQP1 strategy	61
Promotion of Cx26 mutants located in TM4 region for membrane translocation successfully rescued hearing loss	61
Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma	60
Integrated analysis of circulating immune cellular and soluble mediators reveals specific COVID19 signatures at hospital admission with utility for prediction of clinical outcomes	60
Cardiomyocyte-derived small extracellular vesicle: a new mechanism driving diabetic cardiac fibrosis and cardiomyopathy	60
Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury	59
DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury	59
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription	58
Single-nucleus RNA sequencing and spatial transcriptomics reveal an immunosuppressive tumor microenvironment related to metastatic dissemination during pancreatic cancer liver metastasis	58
Activated molecular probes for enzyme recognition and detection	58
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway	57
The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease	57
Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists	56
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis	56
Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo	56
Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma	55
Dysadherin awakens mechanical forces and promotes colorectal cancer progression	55
Intratumoral synthesis of transformable metal-phenolic nanoaggregates with enhanced tumor penetration and retention for photothermal immunotherapy	55
Essential role of IL-17 in acute exacerbation of pulmonary fibrosis induced by non-typeable Haemophilus influenzae	54
Mechanisms and novel therapeutic roles of bitter taste receptors in diseases	54
Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice	53
The metallic compound promotes primordial follicle activation and ameliorates fertility deficits in aged mice	53
Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy	52
Oncofetal TRIM71 drives liver cancer carcinogenesis through remodeling CEBPA-mediated serine/glycine metabolism	52
Honokiol enhances the sensitivity of cetuximab in KRASG13D mutant colorectal cancer through destroying SNX3-retromer complex	51
PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain	51
5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury	51
[161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [177Lu]Lu-PSMA-617	50
Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2	50
Ferroptosis at the nexus of metabolism and metabolic diseases	50
Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration	50
Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease	49
Artificial intelligence-enhanced retinal imaging as a biomarker for systemic diseases	49
Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development	49
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy	49
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging	48
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC	48
Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics	48
Processed microalgae: green gold for tissue regeneration and repair	48
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound	48
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents	48
The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair	48
Multiple regulatory mechanisms, functions and therapeutic potential of chaperone-mediated autophagy	48
Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles	47
Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway	47
βKlotho is identified as a target for theranostics in non-small cell lung cancer: Erratum	47
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke	47
Loss of DDX24 inhibits lung cancer progression by stimulating IKBKG splicing-mediated autophagy	47
Co-delivery of 5-fluorouracil and miRNA-34a mimics by host-guest self-assembly nanocarriers for efficacious targeted therapy in colorectal cancer patient-derived tumor xenografts: Erratum	47
Engineered mesenchymal stem cell-derived extracellular vesicles: A state-of-the-art multifunctional weapon against Alzheimer's disease	47
Intranasal delivery of imaging agents to the brain	46
Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects	46
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors	46
Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle	46

DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo	46
Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies	46
PET imaging of CXCR4 expression using [18F]AlF-NOTA-QHY-04 for hematologic malignancy and solid tumors	45
SUMOylation of SARS-CoV-2 spike protein is a key target for broad-spectrum antiviral therapy	45
A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor	45
X-ray stimulates NQO1-dependent cascade reactions to induce strong immunogenicity for MRI-guided cancer radio-chemodynamic-immunotherapy	45
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation	45
What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake	45
Bioactive metal-protein matrix for promoting MRSA infection wound therapy through bioenergy-induced angiogenesis	44
18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma	44
DNA aptamers inhibit SARS-CoV-2 spike-protein binding to hACE2 by an RBD- independent or dependent approach	44
A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment	44
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex	44
Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway: Erratum	44
Extracellular matrix proteins refine microenvironments for pancreatic organogenesis from induced pluripotent stem cell differentiation	44
Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-κB-mediated epithelial inflammation	43
CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells	43
An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions	43
Targeting HSF1 for cancer treatment: mechanisms and inhibitor development	43
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment	43
Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease	43
Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease	43
Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications	43
Mesenchymal stem cell-derived extracellular vesicles targeting irradiated intestine exert therapeutic effects	42
Advances in subpopulation separation and detection of extracellular vesicles: for liquid biopsy and downstream research	42
Exosomes: innovative biomarkers leading the charge in non-invasive cancer diagnostics	42
An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation	41
Knocking out USP7 attenuates cardiac fibrosis and endothelial-to-mesenchymal transition by destabilizing SMAD3 in mice with heart failure with preserved ejection fraction	41
A novel ferroptosis inhibitor, Thonningianin A, improves Alzheimer's disease by activating GPX4	41
Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice	41
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bo	41
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosis	41
Comprehensive overview of Nrf2-related epigenetic regulations involved in ischemia-reperfusion injury	40
Trop2-targeted therapies in solid tumors: advances and future directions	40
Platinum-based drugs for cancer therapy and anti-tumor strategies	40
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice	40
m6A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism	40
Revolutionizing drug delivery: low-intensity pulsed ultrasound (LIPUS)-driven deep penetration into hypoxic tumor microenvironments of cholangiocarcinoma	39
TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma	39
Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution	39
Faecal microbiome and metabolic signatures in rectal neuroendocrine tumors	39
Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement	39
The evolving understanding of systemic mechanisms in organ-specific IgA nephropathy: a focus on gut-kidney crosstalk	39
From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals	39
Unlocking potential of oxytocin: improving intracranial lymphatic drainage for Alzheimer's disease treatment	38
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis	38
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation	38
Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms	38
CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1	37
Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum	37
LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt	37
Modulation of brain immune microenvironment and cellular dynamics in systemic inflammation	37
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity	37
Nucleic acid-based nanotherapeutics for treating sepsis and associated organ injuries	37
In vivo molecular imaging of breast cancer metabolic heterogeneity using [1-13C]pyruvate-d3 hyperpolarized by reversible exchange with parahydrogen	37
Label-free optical metabolic imaging of adipose tissues for prediabetes diagnosis	37
Thermal-responsive ultrasound activatable in situ production of therapeutics for real-time imaging and targeted tumor therapy	37
Autophagy-enhanced nanosonosensitizer mediated sonodynamic therapy for post-myocardial infarction neuromodulation and arrhythmia prevention	36
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer	36
A novel afterglow nanoreporter for monitoring cancer therapy	36
Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution	36
Disease-associated microglial activation prevents photoreceptor degeneration by suppressing the accumulation of cell debris and neutrophils in degenerating rat retinas	36
Integrative biology of extracellular vesicles in diabetes mellitus and diabetic complications	36
PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis	36
Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination	36
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages	36
Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine	35
Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy	35
The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation	35
Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications	35
SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex	35
Conditional ablation of DIS3L2 ribonuclease in pre-meiotic germ cells causes defective spermatogenesis and infertility in male mice	35
3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration	35
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer	35
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics	35
Emulating interactions between microorganisms and tumor microenvironment to develop cancer theranostics	35
Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds	35
MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury	35
Ultrasound-controlled MXene-based Schottky heterojunction improves anti-infection and osteogenesis properties	35
Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants	35
YBX1-driven TUBB6 upregulation facilitates ocular angiogenesis via WNT3A-FZD8 pathway	34
Inflammatory extracellular vesicles prompt heart dysfunction via TLR4-dependent NF-κB activation: Erratum	34
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration	34
Theranostics in the vasculature: bioeffects of ultrasound and microbubbles to induce vascular shutdown	34
Divergent splicing factor SRSF1 signaling promotes inflammation post-CME: the SRSF1/ENPP3 axis acts via inhibition of BRD4 O-GlcNAcylation to enhance NF-κB activation and accelerate heart failure	34
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing	34
Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy	34
Multiomic analysis for optimization of combined focal and immunotherapy protocols in murine pancreatic cancer	34
Oxidative stress-mediated PANoptosis and ferroptosis: Exploration of multimodal cell death triggered by an AIE-active nano-photosensitizer via photodynamic therapy	34
Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss	34
Retraction of “Universal theranostic CRISPR/Cas13a RNA-editing system for glioma”	34
The basolateral amygdala-anterior cingulate cortex circuit contributes to postherpetic neuralgia-anxiety comorbidity	33
Discovery of indole analogue Tc3 as a potent pyroptosis inducer and identification of its combination strategy against hepatic carcinoma	33
A novel assessment of whole-mount Gleason grading in prostate cancer to identify candidates for radical prostatectomy: a machine learning-based multiomics study	33
A multimodal imaging workflow for monitoring CAR T cell therapy against solid tumor from whole-body to single-cell level	33