Theranostics

Article	Citations
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	703
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	538
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy	446
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	420
A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer	256
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	254
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	245
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	241
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	213
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	206
Recent progress of nano-drugs in neutron capture therapy	190
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation	189
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype	184
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	183
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	182
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	180
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside	174
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	162
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	161
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	160
Targeted delivery of anti-miRNA21 sensitizes PD-L1high tumor to immunotherapy by promoting immunogenic cell death	156
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	155
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	153
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold	152
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	150

5-Aminolevulinate improves metabolic recovery and cell survival of the liver following cold preservation	149
High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease	146
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model	146
The LMIT: Light-mediated minimally-invasive theranostics in oncology	142
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	142
Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism	133
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	133
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy	131
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	129
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage	126
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	125
Noninvasive closed-loop acoustic brain-computer interface for seizure control	123
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	119
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	116
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	116
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	116
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	115
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	113
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	110
The emerging role of Piezo1 in the musculoskeletal system and disease	108
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	106
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms	106
FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts	106
Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity — Introducing High NET Affinity PET Probe 18F-AF78	105
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	104
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability	103
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	103
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease	101
A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum	101
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial: Erratum	101
Kir6.1/K-ATP channel in astrocytes is an essential negative modulator of astrocytic pyroptosis in mouse model of depression	99
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration	99
The first abdominal aortic aneurysm organoid model replicates complex microenvironment for in vitro disease study	98
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	98
TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response	97
Intermittent fasting reprograms the brain proteome to prevent synaptic degeneration and cognitive impairment in vascular dementia	93
First-in-human study of an optimized, potential kit-type, SSTR antagonist 68Ga-DATA5m-LM4 in patients with metastatic neuroendocrine tumors	92
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	92
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	89
Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury	89
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	89
Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization	89
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	89
Optic chiasmatic potential by endoscopically implanted skull base microinvasive biosensor: a brain-machine interface approach for anterior visual pathway assessment	88
Supercharging CAR-T cells through transcriptional and epigenetic armoring	87
Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases	87
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	87
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	87
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	87
NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice	87

Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α: Erratum	86
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis	85
How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?	84
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	83
Unlocking the dual role of LSD1 in tumor immunity: innate and adaptive pathways	83
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	83
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	82
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	82
CBX4 suppresses CD8+ T cell antitumor immunity by reprogramming glycolytic metabolism	82
TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy	81
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	81
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	81
Identification of early invisible acute ischemic stroke in non-contrast computed tomography using two-stage deep-learning model	80
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	80
Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation	80
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	79
Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis	78
Re-engineering the inner surface of ferritin nanocage enables dual drug payloads for synergistic tumor therapy	78
Wound microenvironment-responsive glucose consumption and hydrogen peroxide generation synergistic with azithromycin for diabetic wounds healing	78
Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing	77
Platelet membrane decorated exosomes enhance targeting efficacy and therapeutic index to alleviate arterial restenosis	77
Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development	77
SERS Tags for Biomedical Detection and Bioimaging	75
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication	73
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	73
Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-β species	73
Reduction-responsive RNAi nanoplatform for enhanced cancer sonoimmunotherapy via dual inhibition of mitophagy and Nrf2 pathways	72
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	72
Essential role of IL-17 in acute exacerbation of pulmonary fibrosis induced by non-typeable Haemophilus influenzae	72
The role of lipid metabolic reprogramming in tumor microenvironment	72
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound	72
Single-shot multiparametric MRI for separating T2 effects from dynamic glucose-enhanced contrast	72
Single-nucleus RNA sequencing and spatial transcriptomics reveal an immunosuppressive tumor microenvironment related to metastatic dissemination during pancreatic cancer liver metastasis	71
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription	70
The metallic compound promotes primordial follicle activation and ameliorates fertility deficits in aged mice	70
Honokiol enhances the sensitivity of cetuximab in KRASG13D mutant colorectal cancer through destroying SNX3-retromer complex	69
Dysadherin awakens mechanical forces and promotes colorectal cancer progression	69
Extracellular vehicles-mediated Twsit1 transferred from tumor cells to brain induces depressive-like behaviors via neuronal morphogenesis	68
Noninvasive DWI tracking of hiPSCs differentiation into RTECs in AKI recovery via the KSP promoter-mediated AQP1 strategy	68
Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice	68
PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain	66
High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo Magnetic Particle Imaging	66
Cathelicidin-related antimicrobial peptide protects against enteric pathogen-accelerated type 1 diabetes in mice	66
Integrated analysis of circulating immune cellular and soluble mediators reveals specific COVID19 signatures at hospital admission with utility for prediction of clinical outcomes	66
Processed microalgae: green gold for tissue regeneration and repair	65
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging	65
The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair	65
Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease	63
Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2	63
Engineered mesenchymal stem cell-derived extracellular vesicles: A state-of-the-art multifunctional weapon against Alzheimer's disease	63
Oncofetal TRIM71 drives liver cancer carcinogenesis through remodeling CEBPA-mediated serine/glycine metabolism	63
Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics	63
Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury	63
Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration	63
Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway	62
Promotion of Cx26 mutants located in TM4 region for membrane translocation successfully rescued hearing loss	62
Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma	61
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke	61
Multiple regulatory mechanisms, functions and therapeutic potential of chaperone-mediated autophagy	61
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis	60
Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo	60
Ferroptosis at the nexus of metabolism and metabolic diseases	60
Intratumoral synthesis of transformable metal-phenolic nanoaggregates with enhanced tumor penetration and retention for photothermal immunotherapy	59
The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease	59
Mechanisms and novel therapeutic roles of bitter taste receptors in diseases	59
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC	59
Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy	58
Artificial intelligence-enhanced retinal imaging as a biomarker for systemic diseases	57
Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma	57
[161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [177Lu]Lu-PSMA-617	57
Cardiomyocyte-derived small extracellular vesicle: a new mechanism driving diabetic cardiac fibrosis and cardiomyopathy	56
Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists	56
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway	55
DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury	55
Activated molecular probes for enzyme recognition and detection	55
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents	55
Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle	54
βKlotho is identified as a target for theranostics in non-small cell lung cancer: Erratum	54
Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development	54
Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles	54

5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury	54
X-ray stimulates NQO1-dependent cascade reactions to induce strong immunogenicity for MRI-guided cancer radio-chemodynamic-immunotherapy	54
Co-delivery of 5-fluorouracil and miRNA-34a mimics by host-guest self-assembly nanocarriers for efficacious targeted therapy in colorectal cancer patient-derived tumor xenografts: Erratum	54
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy	54
SUMOylation of SARS-CoV-2 spike protein is a key target for broad-spectrum antiviral therapy	53
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo	53
Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects	53
Advances and challenges in decellularized adipose tissue based composite hydrogels for adipose tissue regeneration: a review over the last fifteen years	53
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors	53
Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-κB-mediated epithelial inflammation	53
Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications	53
Naturally derived hydrogel with antioxidant, angiogenesis and photothermal effect to accelerate infected diabetic wound healing and reduce scar formation	53
Comprehensive overview of Nrf2-related epigenetic regulations involved in ischemia-reperfusion injury	53
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation	52
Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway: Erratum	52
A novel ferroptosis inhibitor, Thonningianin A, improves Alzheimer's disease by activating GPX4	52
Deep brain stimulation-induced normalization of hippocampal synchrony in a transgenic rat model of Alzheimer's disease	52
m6A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism	52
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment	52
A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor	52
PET imaging of CXCR4 expression using [18F]AlF-NOTA-QHY-04 for hematologic malignancy and solid tumors	52
Extracellular matrix proteins refine microenvironments for pancreatic organogenesis from induced pluripotent stem cell differentiation	51
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex	51
Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease	51
DNA aptamers inhibit SARS-CoV-2 spike-protein binding to hACE2 by an RBD- independent or dependent approach	51
What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake	51
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice	51
A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment	50
Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies	50
18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma	50
Loss of DDX24 inhibits lung cancer progression by stimulating IKBKG splicing-mediated autophagy	50
Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease	50
Biofilm-disrupting heterojunction microneedles: dual ROS amplification and glucose deprivation for accelerated diabetic wound healing	49
Trop2-targeted therapies in solid tumors: advances and future directions	49
Bioactive metal-protein matrix for promoting MRSA infection wound therapy through bioenergy-induced angiogenesis	49
Targeting HSF1 for cancer treatment: mechanisms and inhibitor development	49
CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells	49
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosis	49
An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation	49
Exosomes: innovative biomarkers leading the charge in non-invasive cancer diagnostics	48
Knocking out USP7 attenuates cardiac fibrosis and endothelial-to-mesenchymal transition by destabilizing SMAD3 in mice with heart failure with preserved ejection fraction	48
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bo	48
Advances in subpopulation separation and detection of extracellular vesicles: for liquid biopsy and downstream research	48
Mesenchymal stem cell-derived extracellular vesicles targeting irradiated intestine exert therapeutic effects	48
Intranasal delivery of imaging agents to the brain	48
Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice	48
An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions	48
SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex	47
Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement	47
Label-free optical metabolic imaging of adipose tissues for prediabetes diagnosis	47
Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution	47
PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis	47
Platinum-based drugs for cancer therapy and anti-tumor strategies	47
A novel afterglow nanoreporter for monitoring cancer therapy	47
CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1	46
Modulation of brain immune microenvironment and cellular dynamics in systemic inflammation	46
From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals	45
LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt	45
Conditional ablation of DIS3L2 ribonuclease in pre-meiotic germ cells causes defective spermatogenesis and infertility in male mice	45
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation	45
Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds	45
Autophagy-driven lipid regulation by an herbal decoction alleviates cardiac lipotoxicity in severe acute pancreatitis	45
Nucleic acid-based nanotherapeutics for treating sepsis and associated organ injuries	45
Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum	45
Self-Assembling Hydrogels of Naproxen-Conjugated Peptides for Osteoarthritis Treatment	45
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer	44
Thermal-responsive ultrasound activatable in situ production of therapeutics for real-time imaging and targeted tumor therapy	44
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis	44
Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants	44
Revolutionizing drug delivery: low-intensity pulsed ultrasound (LIPUS)-driven deep penetration into hypoxic tumor microenvironments of cholangiocarcinoma	44
Disease-associated microglial activation prevents photoreceptor degeneration by suppressing the accumulation of cell debris and neutrophils in degenerating rat retinas	44
3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration	44
Emulating interactions between microorganisms and tumor microenvironment to develop cancer theranostics	43
Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination	43
Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss	43
Unlocking potential of oxytocin: improving intracranial lymphatic drainage for Alzheimer's disease treatment	43
Autophagy-enhanced nanosonosensitizer mediated sonodynamic therapy for post-myocardial infarction neuromodulation and arrhythmia prevention	43
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing	43
Theranostics in the vasculature: bioeffects of ultrasound and microbubbles to induce vascular shutdown	43
MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury	43
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics	42
Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy	42
Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine	42
TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma	42
Faecal microbiome and metabolic signatures in rectal neuroendocrine tumors	42
Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy	42
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity	42
In vivo molecular imaging of breast cancer metabolic heterogeneity using [1- 13 C]pyruvate-d 3	42
Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution	41
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration	41
Integrative biology of extracellular vesicles in diabetes mellitus and diabetic complications	41
Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications	41
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer	41
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages	41
The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation	41