Theranostics

Article	Citations
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	647
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	256
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	256
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	232
Glucosylceramide regulates depression through activating peroxisome proliferator-activated receptor gamma in dorsal striatum	217
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	210
Self-boosting targeted anticancer therapy via cancer cell self-reprogramming with GGT-targeting oxidative stress nanoamplifiers	209
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	205
The LMIT: Light-mediated minimally-invasive theranostics in oncology	200
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	189
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	172
Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model	172
“Electron transport chain interference” strategy of amplified bacterial ferroptosis and defect-engineered nanozyme for diabetic wound healing	164
Flowerbed-inspired biomimetic 3D-printed scaffolds functionalized with urine-derived stem cell exosomes promote alveolar bone regeneration by regulating energy metabolism	162
Integrating the hallmarks of cancer into autophagy: a perspective from underlying mechanisms to therapeutic strategies	158
Exosomal immune decoy integrates cfDNA scavenging and mTOR inhibition for synergistic lupus nephritis therapy	158
Primary Cilium Forces Neuroendocrine Shift in Prostate Cancer through YAP1 Repression and Reduced Mitochondrial Activity	153
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	140
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	140
Targeted delivery of anti-miRNA21 sensitizes PD-L1high tumor to immunotherapy by promoting immunogenic cell death	133
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	133
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	133
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	130
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	127
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	123

Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	121
A robust asymmetric bioadhesive patch for sutureless intestinal repair to prevent anastomotic leakage and postoperative adhesion	112
Noninvasive closed-loop acoustic brain-computer interface for seizure control	109
Recent progress of nano-drugs in neutron capture therapy	108
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	107
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	105
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	104
Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability	103
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	101
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	99
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	98
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	97
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	97
ASIC1a Induces Excessive Mitophagy and PANoptosis of Chondrocyte by the Inhibition of SIRT3 Mitochondrial Translocation	96
Myeloid cell-specific β2-adrenergic receptor deletion improves early cardiac injury resolution via de-repression of Anxa1	95
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	94
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	94
Biosynthetic gas vesicles as a novel ultrasound contrast agent for diagnosing and treating myocardial infarction	93
Future opportunities and nuances with the use of PSMA PET in prostate cancer (MD PET 1)	92
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	92
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	91
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	90
The emerging role of Piezo1 in the musculoskeletal system and disease	90
First-in-human study of an optimized, potential kit-type, SSTR antagonist 68Ga-DATA5m-LM4 in patients with metastatic neuroendocrine tumors	89
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	89
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	87
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	86
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	85
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	83
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	81
Antibody-induced internalization and degradation of PLA2R amplifies CD4+ T cell activation	81
Supercharging CAR-T cells through transcriptional and epigenetic armoring	80
The first abdominal aortic aneurysm organoid model replicates complex microenvironment for in vitro disease study	79
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	79
Connective tissue growth factor contributes to resistance to anti-angiogenic therapies in renal cancer	79
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	78
TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy	78
Quantitative assessment of extravasation of IL-15-secreting MSLN-CAR-NK-92 cells using tumor transparency imaging	78
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	78
Cell-free secretome of CD56 bright CD16 bright directly reprogrammed NK cells enhances wound heali	77
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	76
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	76
Intermittent fasting reprograms the brain proteome to prevent synaptic degeneration and cognitive impairment in vascular dementia	76
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease	75
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	75
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	75
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	74
Pathologically responsive ZnSrMo-LDH/Cu nanozymes with cascade antioxidant and angiogenic functions for myocardial ischemia-reperfusion treatment	74
Development of a nanoparticle-based immunotherapy targeting CD137 for nasopharyngeal carcinoma treatment	74
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis	73

Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	72
Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing	72
Unlocking the dual role of LSD1 in tumor immunity: innate and adaptive pathways	72
Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis	72
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	71
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	71
Platelet membrane decorated exosomes enhance targeting efficacy and therapeutic index to alleviate arterial restenosis	70
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	69
Honeysuckle-derived nanovesicles alleviate inflammatory bowel disease-associated neuropsychiatric disorders via the gut–brain axis	69
Targeting efferocytosis for tissue regeneration: From microenvironment reprogramming to clinical translation	68
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	68
The role of lipid metabolic reprogramming in tumor microenvironment	68
CBX4 suppresses CD8+ T cell antitumor immunity by reprogramming glycolytic metabolism	67
Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation	66
FGF19 in Solid Tumors: Molecular Mechanisms, Metabolic Reprogramming, and Emerging Therapeutic Opportunities	65
Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma	65
Cardiomyocyte-derived small extracellular vesicle: a new mechanism driving diabetic cardiac fibrosis and cardiomyopathy	64
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke	64
Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury	64
A tumor-targeted heptamethine cyanine dye induces suppression of progesterone receptor activity to treat hormone receptor-positive breast cancer	63
Targeted nanoparticles for placenta-specific drug delivery in pregnant rhesus macaques	63
The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease	63
Oncofetal TRIM71 drives liver cancer carcinogenesis through remodeling CEBPA-mediated serine/glycine metabolism	63
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound	63
Extracellular vehicles-mediated Twsit1 transferred from tumor cells to brain induces depressive-like behaviors via neuronal morphogenesis	63
Reduction-responsive RNAi nanoplatform for enhanced cancer sonoimmunotherapy via dual inhibition of mitophagy and Nrf2 pathways	63
Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy	63
Noninvasive DWI tracking of hiPSCs differentiation into RTECs in AKI recovery via the KSP promoter-mediated AQP1 strategy	62
PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain	61
High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo Magnetic Particle Imaging	61
The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair	60
Unraveling the pleiotropic effects of CCR2-dependent signal transduction in fibrosis development	60
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC	60
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis	60
Bimetallic Cu/Fe-MOF-based heterojunction sonozymes for triple amplification of sono-immunotherapy through activating tumor-specific cuproptosis and cGAS-STING pathway	59
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription	59
Advancements in CRISPR-based therapies for ocular pathologies: from disease mechanisms to intervention strategies	59
Promotion of Cx26 mutants located in TM4 region for membrane translocation successfully rescued hearing loss	59
The metallic compound promotes primordial follicle activation and ameliorates fertility deficits in aged mice	58
Mechanisms and novel therapeutic roles of bitter taste receptors in diseases	58
5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury	58
[161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [177Lu]Lu-PSMA-617	58
Epigenetic and O-glycosylation regulation of p66Shc mitigates mitochondrial oxidative stress in aortic dissection	58
Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway	57
Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists	57
Engineered mesenchymal stem cell-derived extracellular vesicles: A state-of-the-art multifunctional weapon against Alzheimer's disease	57
Honokiol enhances the sensitivity of cetuximab in KRASG13D mutant colorectal cancer through destroying SNX3-retromer complex	57
Ferroptosis at the nexus of metabolism and metabolic diseases	57
Single-nucleus RNA sequencing and spatial transcriptomics reveal an immunosuppressive tumor microenvironment related to metastatic dissemination during pancreatic cancer liver metastasis	56
Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice	56
Artificial intelligence-enhanced retinal imaging as a biomarker for systemic diseases	56
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway	56
Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development	56
The efficacy of oligonucleotide-based gene therapeutics in gene silencing	55
Multiple regulatory mechanisms, functions and therapeutic potential of chaperone-mediated autophagy	55
Lactylation-driven NSUN2 -mediated RNA m5C modification promotes perineural invasion in pancreatic cancer	55
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy	54
Processed microalgae: green gold for tissue regeneration and repair	54
Single-shot multiparametric MRI for separating T2 effects from dynamic glucose-enhanced contrast	54
βKlotho is identified as a target for theranostics in non-small cell lung cancer: Erratum	54
Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma	54
Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration	54
Subtype-Specific Roles of Anterior Cingulate Cortex Neurons in Pain-Induced Social Deficits in Mice	53
Deep brain stimulation-induced normalization of hippocampal synchrony in a transgenic rat model of Alzheimer's disease	53
18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma	53
Targeting CAMK1D-engineered nanoactivator suppresses cancer stem cell maintenance and immune evasion in enzalutamide-resistant prostate cancer	53
Bioactive metal-protein matrix for promoting MRSA infection wound therapy through bioenergy-induced angiogenesis	53
SUMOylation of SARS-CoV-2 spike protein is a key target for broad-spectrum antiviral therapy	52
X-ray stimulates NQO1-dependent cascade reactions to induce strong immunogenicity for MRI-guided cancer radio-chemodynamic-immunotherapy	52
Functionalized metallic nanomaterials, nanozymes and nanomotors for emerging tumor diagnosis and treatment: from design to theranostics strategies	52
A tumor-targeted heptamethine cyanine dye suppresses triple-negative breast cancer by induction of lethal autophagy	52
Fibroblast-derived NEU1 as a therapeutic target for improving cortical bone integrity and fracture healing	52
PET imaging of CXCR4 expression using [18F]AlF-NOTA-QHY-04 for hematologic malignancy and solid tumors	52
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors	51
Intranasal delivery of imaging agents to the brain	51
Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-κB-mediated epithelial inflammation	51
Self-synergizing mutual prodrug liposomes for targeted cancer therapy via redox-amplified Pin1 inhibition	51
Biofilm-disrupting heterojunction microneedles: dual ROS amplification and glucose deprivation for accelerated diabetic wound healing	50
Advances in subpopulation separation and detection of extracellular vesicles: for liquid biopsy and downstream research	50
A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor	50

Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice	49
Mesenchymal stem cell-derived extracellular vesicles targeting irradiated intestine exert therapeutic effects	49
Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects	49
Loss of DDX24 inhibits lung cancer progression by stimulating IKBKG splicing-mediated autophagy	49
Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications	48
Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease	48
Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies	48
Naturally derived hydrogel with antioxidant, angiogenesis and photothermal effect to accelerate infected diabetic wound healing and reduce scar formation	47
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation	47
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo	47
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment	47
Trop2-targeted therapies in solid tumors: advances and future directions	46
Extracellular matrix proteins refine microenvironments for pancreatic organogenesis from induced pluripotent stem cell differentiation	46
A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment	46
An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation	46
Knocking out USP7 attenuates cardiac fibrosis and endothelial-to-mesenchymal transition by destabilizing SMAD3 in mice with heart failure with preserved ejection fraction	46
Bacterial extracellular vesicles as multifaceted regulators of human diseases and emerging therapeutic platforms	46
The B-cell-autoantibody axis in lung cancer immunity	46
From 2D cultures to 3D systems: evolving cancer models at the interface of functional precision medicine and theranostics	46
Targeting HSF1 for cancer treatment: mechanisms and inhibitor development	46
Exosomes: innovative biomarkers leading the charge in non-invasive cancer diagnostics	46
Advances and challenges in decellularized adipose tissue based composite hydrogels for adipose tissue regeneration: a review over the last fifteen years	45
A novel ferroptosis inhibitor, Thonningianin A, improves Alzheimer's disease by activating GPX4	45
BMAL1 regulates tubular epithelial-derived exosomal miR-27a-3p to inhibit macrophage–myofibroblast transition and alleviate ischemia/reperfusion-induced renal fibrosis	45
Recent advances and challenges in hydrogel-based delivery of immunomodulatory strategies for diabetic wound healing	45
Conditional ablation of DIS3L2 ribonuclease in pre-meiotic germ cells causes defective spermatogenesis and infertility in male mice	45
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity	45
Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease	45
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bo	45
On-demand sIPN microneedles promote infected burn wound healing via microenvironment remodeling and activation of the Wnt–KLF5 regenerative axis	45
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosis	45
Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement	44
Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum	44
MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKKβ and inducing IKKβ-mediated FoxO1 nuclear export and Foxp3 downregulation: Erratum	44
T lymphocyte membrane bionic nanomedicine synergizes with radiotherapy for enhancing Mg 2+ -mediated tumor metallo-immunotherapy and preventing recur	44
LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt	44
Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy	44
From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals	43
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer	43
Thermal-responsive ultrasound activatable in situ production of therapeutics for real-time imaging and targeted tumor therapy	43
Label-free optical metabolic imaging of adipose tissues for prediabetes diagnosis	43
Nucleic acid-based nanotherapeutics for treating sepsis and associated organ injuries	43
Targeted Accumulation of Reactive Acrolein via Nanoparticle-embedded Reverse Temperature Hydrogel for Bladder Cancer Treatment	43
Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution	43
Autophagy-driven lipid regulation by an herbal decoction alleviates cardiac lipotoxicity in severe acute pancreatitis	42
In vivo molecular imaging of breast cancer metabolic heterogeneity using [1- 13 C]pyruvate-d 3	42
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation	42
Revolutionizing drug delivery: low-intensity pulsed ultrasound (LIPUS)-driven deep penetration into hypoxic tumor microenvironments of cholangiocarcinoma	42
Modulation of brain immune microenvironment and cellular dynamics in systemic inflammation	42
TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma	42
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer	42
Dissolvable microneedles loaded with denosumab alleviate knee osteoarthritis in rodent and canine models by inhibiting macrophage senescence	41
PSMA-targeting hybrid molecule PSMA-914 for preoperative imaging and intraoperative fluorescence-guidance: A first-in-human experience	41
3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration	41
The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation	41
Piezoelectric Heterojunction-driven Biomedical Revolution: From Construction Principles to Diagnostic and Therapeutic Applications	41
Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants	41
The evolving understanding of systemic mechanisms in organ-specific IgA nephropathy: a focus on gut-kidney crosstalk	41
Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms	41
PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis	40
Theranostics in the vasculature: bioeffects of ultrasound and microbubbles to induce vascular shutdown	40
Self-Assembling Hydrogels of Naproxen-Conjugated Peptides for Osteoarthritis Treatment	40
ROS-responsive cellular vesicles with ferroptosis-targeting siACMSD delivery for acute kidney injury therapy	40
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration	40
Autophagy-enhanced nanosonosensitizer mediated sonodynamic therapy for post-myocardial infarction neuromodulation and arrhythmia prevention	40
Unlocking potential of oxytocin: improving intracranial lymphatic drainage for Alzheimer's disease treatment	39
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing	39
Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine	39
Sono-piezoelectric cues regulate neuroinflammatory reflex-arc-mediated α7nAChR-P2RX7 axis to dampen osteoarthritis-correlated pain with osteoarthritis attenuation	39
Ultrasound-controlled MXene-based Schottky heterojunction improves anti-infection and osteogenesis properties	39
Retraction of “Universal theranostic CRISPR/Cas13a RNA-editing system for glioma”	38
DNA nanorobot for mitochondria-targeted microRNAs detection and tailored regulation	38
Activation of Toll-like receptor 2 promotes mesenchymal stem/stromal cell-mediated immunoregulation and angiostasis through AKR1C1	38
Inflammatory extracellular vesicles prompt heart dysfunction via TLR4-dependent NF-κB activation: Erratum	38
Macroscale pseudo-spheroids fabricated using methacrylated collagen-coated cells	38
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages	38
Lipid nanoparticle-formulated DNA acts as a potent immune modulator for cancer immunotherapy through interferon signaling pathways	38
In vivo spatiotemporal mapping of proliferation activity in gliomas via water-exchange dynamic contrast-enhanced MRI	38
Ultrasound spatiotemporally enables prolonged therapeutic mRNA translation in engineered bacteria for enhanced cancer immunotherapy	37
A dendritic/tumor fusion cell vaccine enhances efficacy of nanobody-based CAR-T cells against solid tumor	37
A cochlea-sparing strategy for non-invasive control of intracranial schwannomas via peripheral irradiation and anti-PD-1 therapy enhanced by STING activation	37
NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover	37
GPA33-pretargeted radioimmunotherapy with mono- and bivalent DOTA-based Lu-177-labeled radiohaptens in a mouse orthotopic liver xenograft model of metastatic human colorectal cancer	37
Mannose and phenylboronate ester functionalized mesoporous silica nanoparticles contained in chitosan microneedles for enhancing cellular immunity and antitumor efficacy	37
Pharmacological inhibition of MDM4 alleviates pulmonary fibrosis	37
Polymer theranostics with multiple stimuli-based activation of photodynamic therapy and tumor imaging	36
A novel assessment of whole-mount Gleason grading in prostate cancer to identify candidates for radical prostatectomy: a machine learning-based multiomics study	36
Discovery of indole analogue Tc3 as a potent pyroptosis inducer and identification of its combination strategy against hepatic carcinoma	36
Condensatopathies as a mechanistic framework for disease and integrated theranostic intervention	36
Mechanosensitive snoRNA-like circular RNA sno-circCNOT1 drives endothelial dysfunction and atherosclerosis	36
YBX1-driven TUBB6 upregulation facilitates ocular angiogenesis via WNT3A-FZD8 pathway	36
Accelerated cartilage regeneration via chondrocyte metabolic reprogramming using nano-steroid-conjugated mesenchymal stem cells in osteoarthritis	35
Divergent splicing factor SRSF1 signaling promotes inflammation post-CME: the SRSF1/ENPP3 axis acts via inhibition of BRD4 O-GlcNAcylation to enhance NF-κB activation and accelerate heart failure	35
Cuproptosis-triggering nanomedicine boosts antitumor immunotherapy	35
Erythroid-transdifferentiated myeloid cells promote portal vein tumor thrombus in hepatocellular carcinoma	35