Theranostics

Article	Citations
A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy	575
Bispecific antibodies targeting EGFR/Notch enhance the response to talazoparib by decreasing tumour-initiating cell frequency	391
Human pluripotent stem cell-derived ectomesenchymal stromal cells promote more robust functional recovery than umbilical cord-derived mesenchymal stromal cells after hypoxic-ischaemic brain damage	344
Comprehensive omics analyses profile genesets related with tumor heterogeneity of multifocal glioblastomas and reveal LIF/CCL2 as biomarkers for mesenchymal subtype	319
Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum	206
Theranostics application of tumor-initiating cell probe TiY in non-small cell lung cancer	200
Highly potent and selective PPARδ agonist reverses memory deficits in mouse models of Alzheimer's disease	199
A low molecular weight multifunctional theranostic molecule for the treatment of prostate cancer	185
Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside	167
Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment	156
A multifunctional injectable microsphere with enhanced near-infrared photo-antibacterial, ROS scavenging, and anti-inflammatory properties for periodontitis treatment	155
A FRET-based off-on AIE nanoprobe enables instant and stain-free detection of hypoxic niches in tumor sections	153
Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression	150
Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis	141
Towards effective CAIX-targeted radionuclide and checkpoint inhibition combination therapy for advanced clear cell renal cell carcinoma	139
The LMIT: Light-mediated minimally-invasive theranostics in oncology	139
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy	134
Transcriptome analysis reveals EBF1 ablation-induced injuries in cardiac system	130
Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis	129
RNF138 regulates skeletal muscle differentiation via the Wnt/β-catenin signaling pathway	127
Nrf2 and HIF1α converge to arsenic-induced metabolic reprogramming and the formation of the cancer stem-like cells: Erratum	127
Molecular Imaging-Derived Biomarker of Cardiac Nerve Integrity — Introducing High NET Affinity PET Probe 18F-AF78	124
3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography	117
A bifunctional fusion membrane-based biocompatible nanovaccine to potentiate cancer immunotherapy	116
Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism	116

Betaine inhibits the stem cell-like properties of hepatocellular carcinoma by activating autophagy via SAM/m6A/YTHDF1-mediated enhancement on ATG3 stability	113
Peptide receptor radionuclide therapy (PRRT) in metastatic neuroendocrine tumors of unknown primary (CUP-NETs)	113
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model	111
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold	110
High-fidelity imaging of amyloid-beta deposits with an ultrasensitive fluorescent probe facilitates the early diagnosis and treatment of Alzheimer's Disease	109
Bisecting GlcNAc modification reverses the chemoresistance via attenuating the function of P-gp	106
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1	105
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma	99
Targeting cancer with precision: strategical insights into TCR-engineered T cell therapies	99
Noninvasive closed-loop acoustic brain-computer interface for seizure control	97
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy	94
Cell-membrane-coated nanoparticles for the fight against pathogenic bacteria, toxins, and inflammatory cytokines associated with sepsis	93
Discovery of novel antibacterial agent for the infected wound treatment: all-hydrocarbon stapling optimization of LL-37	93
A p-n heterojunction sonosensitizer for improved sono-immunotherapy via induction of multimodal cell death mechanisms	92
AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics	91
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms	91
5-Aminolevulinate improves metabolic recovery and cell survival of the liver following cold preservation	89
Perfluorocarbon-polyepinephrine core-shell nanoparticles as a near-infrared light activatable theranostic platform for bimodal imaging-guided photothermal/chemodynamic synergistic cancer therapy	88
FGFR blockade boosts T cell infiltration into triple-negative breast cancer by regulating cancer-associated fibroblasts	88
Targeted delivery of anti-miRNA21 sensitizes PD-L1high tumor to immunotherapy by promoting immunogenic cell death	87
Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis	86
Recent progress of nano-drugs in neutron capture therapy	86
FUNDC1 alleviates doxorubicin-induced cardiotoxicity by restoring mitochondrial-endoplasmic reticulum contacts and blocked autophagic flux	85
The emerging role of Piezo1 in the musculoskeletal system and disease	83
Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy	83
Acute cellular and vascular responses to photodynamic therapy using EGFR-targeted nanobody-photosensitizer conjugates studied with intravital optical imaging and magnetic resonance imaging: Erratum	83
Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial: Erratum	82
Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice: Erratum	81
Dual-Targeted Gold Nanoprism for Recognition of Early Apoptosis, Dual-Model Imaging and Precise Cancer Photothermal Therapy: Erratum	80
Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α: Erratum	80
First-in-human study of an optimized, potential kit-type, SSTR antagonist 68Ga-DATA5m-LM4 in patients with metastatic neuroendocrine tumors	80
A Transferrin-Conjugated Hollow Nanoplatform for Redox-Controlled and Targeted Chemotherapy of Tumor with Reduced Inflammatory Reactions: Erratum	79
Coupling CRISPR-Cas and a personal glucose meter with an enzymatic reporter for portable detection of human papillomavirus in biological samples	77
Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy	77
Optic chiasmatic potential by endoscopically implanted skull base microinvasive biosensor: a brain-machine interface approach for anterior visual pathway assessment	77
KMV-mediated cardiomyocyte-to-endothelial cell signaling drives capillary rarefaction to promote heart failure following pressure overload	75
Supercharging CAR-T cells through transcriptional and epigenetic armoring	75
Platelet membrane decorated exosomes enhance targeting efficacy and therapeutic index to alleviate arterial restenosis	74
Inhibiting the activation of MAPK (ERK1/2) in stressed Müller cells prevents photoreceptor degeneration	74
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy	73
Kir6.1/K-ATP channel in astrocytes is an essential negative modulator of astrocytic pyroptosis in mouse model of depression	72
Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma	72
Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis: Erratum	70
TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response	70
Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting	70
Identification of early invisible acute ischemic stroke in non-contrast computed tomography using two-stage deep-learning model	70
Multiple crosslinked, self-healing, and shape-adaptable hydrogel laden with pain-relieving chitosan@borneol nanoparticles for infected burn wound healing	69
NAD+-boosting molecules suppress mast cell degranulation and anaphylactic responses in mice	69
Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection	69
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease	68

Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer	68
Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-β species	68
CBX4 suppresses CD8+ T cell antitumor immunity by reprogramming glycolytic metabolism	66
The interplay between non-coding RNAs and alternative splicing: from regulatory mechanism to therapeutic implications in cancer	66
Weak acid-initiated slow release of Dexamethasone from hydrogel to treat orbital inflammation	65
Biomechanical microenvironment in peripheral nerve regeneration: from pathophysiological understanding to tissue engineering development	64
Resveratrol ameliorates polycystic ovary syndrome via transzonal projections within oocyte-granulosa cell communication	64
Targeting formyl peptide receptor 2 to suppress neuroinflammation in neuromyelitis optica spectrum disorder	64
Phosphorus dendron nanomicelles as a platform for combination anti-inflammatory and antioxidative therapy of acute lung injury	64
Re-engineering the inner surface of ferritin nanocage enables dual drug payloads for synergistic tumor therapy	64
Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases	63
TRIM4 enhances small-molecule-induced neddylated-degradation of CORO1A for triple negative breast cancer therapy	63
How to improve photodynamic therapy-induced antitumor immunity for cancer treatment?	62
Pre-metastatic niche: from revealing the molecular and cellular mechanisms to the clinical applications in breast cancer metastasis	61
Collagen type I PET/MRI enables evaluation of treatment response in pancreatic cancer in pre-clinical and first-in-human translational studies	61
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis	59
Wound microenvironment-responsive glucose consumption and hydrogen peroxide generation synergistic with azithromycin for diabetic wounds healing	59
Unlocking the dual role of LSD1 in tumor immunity: innate and adaptive pathways	58
SERS Tags for Biomedical Detection and Bioimaging	58
Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization	58
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution	58
The role of lipid metabolic reprogramming in tumor microenvironment	58
Revolutionizing cancer treatment: the emerging potential and potential challenges of in vivo self-processed CAR cell therapy	57
Integrated analysis of circulating immune cellular and soluble mediators reveals specific COVID19 signatures at hospital admission with utility for prediction of clinical outcomes	57
Avoiding the self-nucleation interference: a pH-regulated gold in situ growth strategy to enable ultrasensitive immunochromatographic diagnostics	57
Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma	57
Focused ultrasound ablation of melanoma with boiling histotripsy yields abscopal tumor control and antigen-dependent dendritic cell activation	57
Cathelicidin-related antimicrobial peptide protects against enteric pathogen-accelerated type 1 diabetes in mice	57
High-efficiency magnetophoretic labelling of adoptively-transferred T cells for longitudinal in vivo Magnetic Particle Imaging	56
The orchestration of cell-cycle reentry and ribosome biogenesis network is critical for cardiac repair	56
Targeted opening of the blood-brain barrier using VCAM-1 functionalised microbubbles and “whole brain” ultrasound	56
[161Tb]Tb-PSMA-617 radioligand therapy in patients with mCRPC: preliminary dosimetry results and intra-individual head-to-head comparison to [177Lu]Lu-PSMA-617	56
Single-nucleus RNA sequencing and spatial transcriptomics reveal an immunosuppressive tumor microenvironment related to metastatic dissemination during pancreatic cancer liver metastasis	56
Noninvasive DWI tracking of hiPSCs differentiation into RTECs in AKI recovery via the KSP promoter-mediated AQP1 strategy	56
Multiple regulatory mechanisms, functions and therapeutic potential of chaperone-mediated autophagy	55
Promotion of Cx26 mutants located in TM4 region for membrane translocation successfully rescued hearing loss	55
Cardiomyocyte-derived small extracellular vesicle: a new mechanism driving diabetic cardiac fibrosis and cardiomyopathy	54
Activated molecular probes for enzyme recognition and detection	54
Artificial intelligence-enhanced retinal imaging as a biomarker for systemic diseases	54
Dysadherin awakens mechanical forces and promotes colorectal cancer progression	53
Mechanisms and novel therapeutic roles of bitter taste receptors in diseases	53
Morphine- and foot shock-responsive neuronal ensembles in the VTA possess different connectivity and biased GPCR signaling pathway	52
Essential role of IL-17 in acute exacerbation of pulmonary fibrosis induced by non-typeable Haemophilus influenzae	52
The metallic compound promotes primordial follicle activation and ameliorates fertility deficits in aged mice	52
Repopulated retinal microglia promote Müller glia reprogramming and preserve visual function in retinal degenerative mice	52
Circular RNA SCMH1 suppresses KMO expression to inhibit mitophagy and promote functional recovery following stroke	51
DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury	51
Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury	50
Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists	49
Honokiol enhances the sensitivity of cetuximab in KRASG13D mutant colorectal cancer through destroying SNX3-retromer complex	49
Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2	49
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription	49
iNOS aggravates pressure overload-induced cardiac dysfunction via activation of the cytosolic-mtDNA-mediated cGAS-STING pathway	49
Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy	48
Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration	48
Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development	48
The biphasic role of Hspb1 on ferroptotic cell death in Parkinson's disease	48
Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease	48
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis	47
Oncofetal TRIM71 drives liver cancer carcinogenesis through remodeling CEBPA-mediated serine/glycine metabolism	47
PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain	47
FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC	46
Processed microalgae: green gold for tissue regeneration and repair	46
Ferroptosis at the nexus of metabolism and metabolic diseases	46
5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury	45
Intratumoral synthesis of transformable metal-phenolic nanoaggregates with enhanced tumor penetration and retention for photothermal immunotherapy	45
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy	45
Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma	45
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging	45
Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents	45
Engineered mesenchymal stem cell-derived extracellular vesicles: A state-of-the-art multifunctional weapon against Alzheimer's disease	45
Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIδ pathway in vitro and in vivo	44
Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle	44
Co-delivery of 5-fluorouracil and miRNA-34a mimics by host-guest self-assembly nanocarriers for efficacious targeted therapy in colorectal cancer patient-derived tumor xenografts: Erratum	44
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo	44
Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles	44
Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway: Erratum	44
Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-κB-mediated epithelial inflammation	44
βKlotho is identified as a target for theranostics in non-small cell lung cancer: Erratum	44
A versatile nanoplatform with excellent biofilm permeability and spatiotemporal ROS regulation for peri-implantitis treatment	43

Development of a CD39 nanobody and its enhancement to chimeric antigen receptor T cells efficacy against ovarian cancer in preclinical studies	43
Knocking out USP7 attenuates cardiac fibrosis and endothelial-to-mesenchymal transition by destabilizing SMAD3 in mice with heart failure with preserved ejection fraction	43
Magnetic sculpture-like tumor cell vaccines enable targeted in situ immune activation and potent antitumor effects	43
CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells	43
Loss of DDX24 inhibits lung cancer progression by stimulating IKBKG splicing-mediated autophagy	43
A H2S-activated NIR-II imaging probe for precise diagnosis and pathological evaluation of colorectal tumor	43
Exosomes: innovative biomarkers leading the charge in non-invasive cancer diagnostics	43
Advances in subpopulation separation and detection of extracellular vesicles: for liquid biopsy and downstream research	43
PET imaging of CXCR4 expression using [18F]AlF-NOTA-QHY-04 for hematologic malignancy and solid tumors	43
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors	43
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex	42
Modulation of H4K16Ac levels reduces pro-fibrotic gene expression and mitigates lung fibrosis in aged mice	42
18F-5-fluoro-aminosuberic acid PET/CT imaging of oxidative-stress features during the formation of DEN-induced rat hepatocellular carcinoma	42
A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation	42
Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment	41
DNA aptamers inhibit SARS-CoV-2 spike-protein binding to hACE2 by an RBD- independent or dependent approach	41
Extracellular matrix proteins refine microenvironments for pancreatic organogenesis from induced pluripotent stem cell differentiation	41
X-ray stimulates NQO1-dependent cascade reactions to induce strong immunogenicity for MRI-guided cancer radio-chemodynamic-immunotherapy	40
Intranasal delivery of imaging agents to the brain	40
SUMOylation of SARS-CoV-2 spike protein is a key target for broad-spectrum antiviral therapy	40
Disturbed flow impairs MerTK-mediated efferocytosis in aortic endothelial cells during atherosclerosis	40
Mesenchymal stem cell-derived extracellular vesicles targeting irradiated intestine exert therapeutic effects	40
Bioactive metal-protein matrix for promoting MRSA infection wound therapy through bioenergy-induced angiogenesis	40
Targeting HSF1 for cancer treatment: mechanisms and inhibitor development	40
Trop2-targeted therapies in solid tumors: advances and future directions	39
What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake	39
Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications	39
Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease	39
An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions	38
Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease	38
m6A-induced lncDBET promotes the malignant progression of bladder cancer through FABP5-mediated lipid metabolism	38
Platinum-based drugs for cancer therapy and anti-tumor strategies	38
A novel ferroptosis inhibitor, Thonningianin A, improves Alzheimer's disease by activating GPX4	38
Nicotinamide phosphoribosyltransferase prompts bleomycin-induced pulmonary fibrosis by driving macrophage M2 polarization in mice	37
PIM1 instigates endothelial-to-mesenchymal transition to aggravate atherosclerosis	37
Revolutionizing drug delivery: low-intensity pulsed ultrasound (LIPUS)-driven deep penetration into hypoxic tumor microenvironments of cholangiocarcinoma	37
An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation	37
Autophagy-enhanced nanosonosensitizer mediated sonodynamic therapy for post-myocardial infarction neuromodulation and arrhythmia prevention	37
Tumor-selective dye-based histological electrophoresis enables intraoperative tumor diagnosis via tumor-specific enhancement	37
Comprehensive overview of Nrf2-related epigenetic regulations involved in ischemia-reperfusion injury	37
Multifunctional injectable hydrogel system as a mild photothermal-assisted therapeutic platform for programmed regulation of inflammation and osteo-microenvironment for enhanced healing of diabetic bo	37
The evolving understanding of systemic mechanisms in organ-specific IgA nephropathy: a focus on gut-kidney crosstalk	37
Thermal-responsive ultrasound activatable in situ production of therapeutics for real-time imaging and targeted tumor therapy	36
From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals	36
Modulation of brain immune microenvironment and cellular dynamics in systemic inflammation	36
Unlocking potential of oxytocin: improving intracranial lymphatic drainage for Alzheimer's disease treatment	36
LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt	36
Low hepatic artery blood flow mediates NET extravasation through the regulation of PIEZO1/SRC signaling to induce biliary complications after liver transplantation	36
Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants	35
Evans blue-modified radiolabeled fibroblast activation protein inhibitor as long-acting cancer therapeutics	35
CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1	35
Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression: Erratum	35
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity	35
Lactate-mediated Fascin protrusions promote cell adhesion and migration in cervical cancer	35
Disease-associated microglial activation prevents photoreceptor degeneration by suppressing the accumulation of cell debris and neutrophils in degenerating rat retinas	34
Faecal microbiome and metabolic signatures in rectal neuroendocrine tumors	34
TFEB promotes Ginkgetin-induced ferroptosis via TRIM25 mediated GPX4 lysosomal degradation in EGFR wide-type lung adenocarcinoma	34
In vivo molecular imaging of breast cancer metabolic heterogeneity using [1-13C]pyruvate-d3 hyperpolarized by reversible exchange with parahydrogen	34
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration	34
SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex	34
Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy	34
A novel afterglow nanoreporter for monitoring cancer therapy	34
Inhibitor screening using microarray identifies the high capacity of neutralizing antibodies to Spike variants in SARS-CoV-2 infection and vaccination	34
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer	34
MiR-155 deficiency protects renal tubular epithelial cells from telomeric and genomic DNA damage in cisplatin-induced acute kidney injury	34
Mesenchymal stromal cells and alpha-1 antitrypsin have a strong synergy in modulating inflammation and its resolution	34
Label-free optical metabolic imaging of adipose tissues for prediabetes diagnosis	34
Signatures of EMT, immunosuppression, and inflammation in primary and recurrent human cutaneous squamous cell carcinoma at single-cell resolution	34
Emulating interactions between microorganisms and tumor microenvironment to develop cancer theranostics	34
DCLK1 promotes colorectal cancer stemness and aggressiveness via the XRCC5/COX2 axis	33
Nucleic acid-based nanotherapeutics for treating sepsis and associated organ injuries	33
Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds	33
Bifidobacterium breve-derived indole-3-lactic acid ameliorates colitis-associated tumorigenesis by directing the differentiation of immature colonic macrophages	33
3D bioprinting of prefabricated artificial skin with multicomponent hydrogel for skin and hair follicle regeneration	33
Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine	33
Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss	33
Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications	33
Theranostics in the vasculature: bioeffects of ultrasound and microbubbles to induce vascular shutdown	33
The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation	32
Multiomic analysis for optimization of combined focal and immunotherapy protocols in murine pancreatic cancer	32
Real-time monitoring of single dendritic cell maturation using deep learning-assisted surface-enhanced Raman spectroscopy	32
Ultrasound-controlled MXene-based Schottky heterojunction improves anti-infection and osteogenesis properties	32
MRI guided copper deprivator activated immune responses and suppressed angiogenesis for enhanced antitumor immunotherapy	32
USP14 modulates stem-like properties, tumorigenicity, and radiotherapy resistance in glioblastoma stem cells through stabilization of MST4-phosphorylated ALKBH5	32
Conditional ablation of DIS3L2 ribonuclease in pre-meiotic germ cells causes defective spermatogenesis and infertility in male mice	32
Integrative biology of extracellular vesicles in diabetes mellitus and diabetic complications	32
Inflammatory extracellular vesicles prompt heart dysfunction via TLR4-dependent NF-κB activation: Erratum	32
Retraction of “Universal theranostic CRISPR/Cas13a RNA-editing system for glioma”	32
Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms	32
Mechanosensitive protein polycystin-1 promotes periosteal stem/progenitor cells osteochondral differentiation in fracture healing	32
Discovery of indole analogue Tc3 as a potent pyroptosis inducer and identification of its combination strategy against hepatic carcinoma	31
A novel assessment of whole-mount Gleason grading in prostate cancer to identify candidates for radical prostatectomy: a machine learning-based multiomics study	31
In vivo spatiotemporal mapping of proliferation activity in gliomas via water-exchange dynamic contrast-enhanced MRI	31
Accurate programmed multifunctional nano-missiles for self-promoted deep delivery and synergistic cascade tumor therapy: Tactfully collaborating chemosynthesis with tumor microenvironment remodeling	31
Biomimetic piezoelectric hydrogel system for energy metabolism reprogramming in spinal cord injury repair	31