OOIR: Observatory of International Research

Papers

(The H4-Index of ChemMedChem is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Fluorinated High‐Valent Sn(IV) Porphyrins Show Remarkable Photodynamic Activity in Cancer Cells	209
	116
Nicorandil Repurposing in Orofacial Pain: Preclinical Findings in Adult Zebrafish	79
Importance of Co‐operative Hydrogen Bonding in the Apramycin‐Ribosomal Decoding A‐Site Interaction	75
	71
Front Cover: Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space (ChemMedChem 5/2024) (ChemMedChem 5/2024)	65
Scouting Different Phosphodiesterase 4 Inhibitor Chemotypes in Silico To Guide the Design of Anti‐inflammatory/Antioxidant Agents	60
Design and Synthesis of 1,3‐Diynes as Potent Antifungal Agents against Aspergillus fumigatus	58
	53
Phosphate‐Containing Glycolipids: A Review on Synthesis and Bioactivity	50
Anti‐Sporothrix Activity of Novel Copper‐Itraconazole Complexes	50
Designing Cyclic Nitrogen‐Bridged Sulfonamides with Anti‐Cancer Activity	48
Front Cover: (ChemMedChem 12/2025)	47
“Cofactors” for Natural Products	47
Front Cover: Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach (ChemMedChem 10/2022)	45
CYP3A4 Catalyzes the Rearrangement of the Dual Orexin Receptor Antagonist Daridorexant to 4‐Hydroxypiperidinol Metabolites	45
Quantum Osteoimmunology: A Paradigm Shift in Understanding and Influencing Bone–Immune Crosstalk	44
C9‐Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α‐Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration	41
Insights into the Overcoming EGFR^{Del19/T790M/C797S} Mutation: A Perspective on the 2‐Aryl‐4‐aminothienopyrimidine Backbone	38
Late‐Stage Diversification of Pyrazoles as Antileishmanial Agents	34
Adsorption to the Surface of Hemozoin Crystals: Structure‐Based Design and Synthesis of Amino‐Phenoxazine β‐Hematin Inhibitors	33
Hepatic‐Targeted Nano‐enzyme with Resveratrol Loading for Precise Relief of Nonalcoholic Steatohepatitis	30
Substituted Benzylidene‐3‐Oxo‐3,4‐Dihydro‐2 H ‐Benzo[ b ][1,4]thiazine‐6‐Carboxylic Acid Analogs as Dynami	30
An Active Member of the EFMC: The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society**	30
Chemical Design Strategy of Ionizable Lipids for In Vivo mRNA Delivery	29

API‐ILs Ionic Adducts: Solubility and Surface Activity Properties—En Route to New Paradigm in Drug Development	29
Cyclin‐Dependent Kinase 11: Cellular Functions and Potential Therapeutic Applications	28
Optimization of Ketobenzothiazole‐Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication	27
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4	27