ChemMedChem

Article	Citations
	141
	130
Synthesis of trans‐Fused 3,6‐Anhydro Hexofuranose Frameworks via Catalytic Hydrogenolysis Triggered Debenzylative Intramolecular Acetalation	91
Improving Strategies in the Development of Protein‐Downregulation‐Based Antiandrogens	69
Front Cover: Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors (ChemMedChem 9/2024)	58
	57
	55
Front Cover: Targeted Redox Balancing through Pulmonary Nanomedicine Delivery Reverses Oxidative Stress Induced Lung Inflammation (ChemMedChem 11/2024)	55
Coordinated Axial Ligand and d‐π Conjugated Network Makes the Difference: Engineered 2D Mn‐Based Antioxidase Mimic for Enhancing Stem Cell Protection	54
	52
	48
“Cofactors” for Natural Products	47
	47
CORRIGENDUM: Carboranes as Potent Phenyl Mimetics: A Comparative Study on the Reversal of ABCG2‐Mediated Drug Resistance by Carboranylquinazolines and Their Organic Isosteres	46
Sulfonamide Bioisosteres of Niclosamide Enhance Antibacterial Activity of Colistin and Bacitracin	45
In Silico Prediction of ERRα Agonists Based on Combined Features and Stacking Ensemble Method	44
Intracellular Delivery of Antisense Oligonucleotides by Tri‐Branched Cyclic Disulfide Units	44
Cover Feature: The IMS Library: from IN‐Stock to Virtual (ChemMedChem 20/2024)	43
	39
Front Cover: Developing Low Molecular Weight PET and SPECT Imaging Agents (ChemMedChem 15/2024)	39
	38
Anti‐Sporothrix Activity of Novel Copper‐Itraconazole Complexes	38
Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library	37
A Structure‐Activity Relationship Study of Amino Acid Derivatives of Pterostilbene Analogues Toward Human Breast Cancer	37
Front Cover: Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach (ChemMedChem 10/2022)	37

Russell Mechanism‐Mediated Cancer Therapy: A Minireview	37
Chemical Derivatization Leads to the Discovery Of Novel Analogs of Azotochelin, a Natural Siderophore, as Promising Anticancer Agents	35
	34
Front Cover: Prodrug Approach to Exploit (S)‐Alanine Amide as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors (ChemMedChem 17/2024)	32
	32
Sphaeropsidin A C15–C16 Cross‐Metathesis Analogues with Potent Anticancer Activity	32
	32
Design and Synthesis of Novel 2‐Acetamido, 6‐Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors – In vitro Evaluation of their Antiproliferative Activity	30
Front Cover: r‐BRICS – A Revised BRICS Module That Breaks Ring Structures and Carbon Chains (ChemMedChem 4/2024)	30
C9‐Functionalized Doxycycline Analogs as Drug Candidates to Prevent Pathological α‐Synuclein Aggregation and Neuroinflammation in Parkinson's Disease Degeneration	30
	29
Synthesis and in vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides	29
Front Cover: Stabilizing Pseudouridimycin: Synthesis, RNA Polymerase Inhibitory Activity, and Antibacterial Activity of Dipeptide‐Modified Analogues (ChemMedChem 1/2024)	29
	28
Front Cover: Design Principles for Balancing Lipophilicity and Permeability in beyond Rule of 5 Space (ChemMedChem 5/2024) (ChemMedChem 5/2024)	28
Development of Kinase‐Centric Drugs: A Computational Perspective	28
Novel Phenyl‐Based Bis‐quaternary Ammonium Compounds as Broad‐Spectrum Biocides	27
Front Cover: (R)‐PFI‐2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7 (ChemMedChem 23/2023)	27
	27
Moving out of CF3‐Land: Synthesis, Receptor Affinity, and in silico Studies of NK1 Receptor Ligands Containing a Pentafluorosulfanyl (SF5) Group	27
Mycobacterial Membrane Protein Large 3 (MmpL3) Inhibitors: A Promising Approach to Combat Tuberculosis	26
Adsorption to the Surface of Hemozoin Crystals: Structure‐Based Design and Synthesis of Amino‐Phenoxazine β‐Hematin Inhibitors	26
The Impact of Activity‐Based Protein Profiling in Malaria Drug Discovery	26
Evaluation of Rhodanine Indolinones as AANAT Inhibitors	25
Naturally Occurring and Widespread Resistance to Bioactive Natural Products	25
Design, Synthesis, and Bioactivity Evaluations of 3‐Methylenechroman‐2‐one Derivatives as Thioredoxin Reductase (TrxR) Inhibitors	24
Expanding the Variety of Pyridinium‐Based Bis‐QACs with Antimicrobial Properties: Investigation into Linker Structure‐Activity Correlation	23
Design, Synthesis and Biological Evaluation of Novel Anticancer Amidinourea Analogues via Unexpected 1,3,5‐Triazin‐2‐one Ring Opening	23
Highlights from the Lowlands: Early Career Researchers Shine at Medicinal Chemistry Frontiers 2024	22
Targeting N‐Methyl‐lysine Histone Demethylase KDM4 in Cancer: Natural Products Inhibitors as a Driving Force for Epigenetic Drug Discovery	22
Thiazole‐Based IL‐17 Inhibitors Discovered by Scaffold Morphing	22
Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands	22
Front Cover: Carborane Conjugates with Ibuprofen, Fenoprofen and Flurbiprofen: Synthesis, Characterization, COX Inhibition Potential and In Vitro Activity (ChemMedChem 1/2025)	21
Gaucher Disease: A Glance from a Medicinal Chemistry Perspective	21
	21
Dual Centrifugation‐Based Screening for pH‐Responsive Liposomes	21
Seeing in the Future – a Perspective on Combining Light with Chemical Biology Approaches to Treat Retinal Pathologies	21
Front Cover: Structural Development of Androgen Receptor Antagonists Using Phenylferrocene Framework as a Hydrophobic Pharmacophore (ChemMedChem 6/2024)	21
Diastereoselective Cascade Double Michael Addition to Access Bridged Coumarins, Oxindoles and Spirooxindoles: A Sustainable Strategy for Synthesis of Anticancer Molecules	21
Straightforward Synthesis of DFO* ‐ An Octadentate Chelator for Zirconium‐89	20
RNA oligomers at atomic resolution containing 1‐methylpseudouridine, an essential building block of mRNA vaccines	20
Novel Octahedral Nickel (II) Complex with Flexible Piperazinyl Moiety Exhibits Potent Cytotoxic Effect Along with Anti‐Migratory and Anti‐Metastatic Effect on Human Cancer Cells	20
An Investigation on Linker Modifications of Cyanoguanidine‐Based P2X7 Receptor Antagonists	20
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4	19
Cyclodextrin Dimers Functionalized with Biotin as Nanocapsules for Active Doxorubicin Delivery Against MCF‐7 Breast Cell Line	19
Phosphate‐Containing Glycolipids: A Review on Synthesis and Bioactivity	19
Native State Stabilization of Amyloidogenic Proteins by Kinetic Stabilizers: Inhibition of Protein Aggregation and Clinical Relevance	18
Late‐Stage Diversification of Pyrazoles as Antileishmanial Agents	18
Aniquinazoline B, a Fungal Natural Product, Activates the μ‐Opioid Receptor	18
Discovery of Antitumor Active Peptides Derived from Peroxiredoxin 5	18

Evaluation of a Radioiodinated G‐Quadruplex Binder in Cervical Cancer Models	18
Ideas Behind the Tryptophan‐Mediated Petasis Reaction (TMPR) Concept for Peptide Stapling	17
A Promising Approach to Target Colorectal Cancer Using Hybrid Triarylmethanes	17
Fluorinated High‐Valent Sn(IV) Porphyrins Show Remarkable Photodynamic Activity in Cancer Cells	17
Molecular Nanoarchitectonics of Natural Photosensitizers and Their Derivatives Nanostructures for Improved Photodynamic Therapy	17
The Hydrazine Moiety in the Synthesis of Modified Nucleosides and Nucleotides	17
Generation of Molecular Counterfactuals for Explainable Machine Learning Based on Core‐Substituent Recombination	17
Design, Synthesis, and in Vitro Evaluation of 4‐(4‐Hydroxyphenyl)piperazine‐Based Compounds Targeting Tyrosinase	17
Glass Box and Black Box Machine Learning Approaches to Exploit Compositional Descriptors of Molecules in Drug Discovery and Aid the Medicinal Chemist	17
Organofluorine Hydrazone Derivatives as Multifunctional Anti‐Alzheimer's Agents with CK2 Inhibitory and Antioxidant Features	17
Chemical Design Strategy of Ionizable Lipids for In Vivo mRNA Delivery	17
Breaking Barriers in Photothermal Tumor Therapy: A Cascade of Strain‐Engineered Nanozyme in Action	16
Exploring Derivatives of Quinolizidine Alkaloid Sophoridine in the Design and Biological Mechanistic Evaluation of Histone Deacetylase Inhibitors against Triple‐Negative Breast Cancer	16
Emergence of Quantum Dots as Innovative Tools for Early Diagnosis and Advanced Treatment of Breast Cancer	16
Insights into the Overcoming EGFRDel19/T790M/C797S Mutation: A Perspective on the 2‐Aryl‐4‐aminothienopyrimidine Backbone	16
Corrigendum: Discovery and Characterization of Multiple Classes of Human CatSper Blockers	16
Flavonoid‐Quinoxaline Hybrid Compounds as Cathepsin Inhibitors Against Fascioliasis	16
Diagnosis and Therapeutic Strategies Based on Nucleic Acid Aptamers Selected against Pseudomonas aeruginosa: The Challenge of Cystic Fibrosis	16
Developing Allosteric Inhibitors of SARS‐CoV‐2 RNA‐Dependent RNA Polymerase	15
Discovery of Antimetastatic Chiral Ionone Alkaloid Derivatives Targeting HIF‐1α/VEGF/VEGFR2 Pathway	15
Corrigendum: Covalent Complex of DNA and Bacterial Topoisomerase: Implications in Antibacterial Drug Development	15
The Spanish Society of Medicinal Chemistry: Promoting Pharmaceutical R&D in Spain since 1977	15
Synthesis and Anticancer Evaluation of Disubstituted Benzimidazoles via One‐Pot Telescopic Grinding Approach	15
Nanoradiopharmaceuticals: An Attractive Concept in Oncotherapy	15
DOTAP Modified Formulations of Aminoacid Based Cationic Liposomes for Improved Gene Delivery and Cell Viability	15
Interaction of a Triantennary Quinoline Glycoconjugate with the Asialoglycoprotein Receptor	14
Exploration of Ligand‐receptor Binding and Mechanisms for Alginate Reduction and Phenotype Reversion by Mucoid Pseudomonas aeruginosa	14
Computer‐Aided Search for 5‐Arylideneimidazolone Anticancer Agents Able To Overcome ABCB1‐Based Multidrug Resistance	14
Structure‐Activity Relationship and Mode‐Of‐Action Studies Highlight 1‐(4‐Biphenylylmethyl)‐1H‐imidazole‐Derived Small Molecules as Potent CYP121 Inhibitors	14
Repurposing Anticancer Drugs To Tackle Malaria	14
Fragment‐Based Drug Discovery for RNA Targets	14
Self‐Assembled Porphyrinoids: One‐Component Nanostructured Photomedicines	14
A Small Molecule with Bridged Carbonyl and Tri‐fluoro‐aceto‐phenone Groups Impedes Microtubule Dynamics and Subsequently Triggers Cancer Cell Apoptosis	13
MPI8 is Potent against SARS‐CoV‐2 by Inhibiting Dually and Selectively the SARS‐CoV‐2 Main Protease and the Host Cathepsin L**	13
Synthesis of Isocryptolepine‐Triazole Adducts and Evaluation of Their Cytotoxic Activity	13
Anticancer Activity and Mechanism of Action Evaluation of an Acylhydrazone Cu(II) Complex toward Breast Cancer Cells, Spheroids, and Mammospheres	13
Promising Antifungal and Antibacterial Agents Based on 5‐Aryl‐2,2′‐bipyridines and Their Heteroligand Salicylate Metal Complexes: Synthesis, Bioevaluation, Molecular Docking	13
Halogen‐Dance‐Based Synthesis of Phosphonomethoxyethyl (PME) Substituted 2‐Aminothiazoles as Potent Inhibitors of Bacterial Adenylate Cyclases	13
Structural Development of Salicylanilide‐Based SPAK Inhibitors as Candidate Antihypertensive Agents	13
Chalcone‐Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering	13
Calcification‐Based Cancer Diagnosis and Therapy	13
Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity	13
Decoration of Squalenoyl‐Gemcitabine Nanoparticles with Squalenyl‐Hydroxybisphosphonate for the Treatment of Bone Tumors	13
Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus	13
RhII‐Catalyzed De‐symmetrization of Ethane‐1,2‐dithiol and Propane‐1,3‐dithiol Yields Metallo‐β‐lactamase Inhibitors	13
In vitro and Microbiological Assay of Functionalized Hybrid Nanomaterials To Validate Their Efficacy in Nanotheranostics: A Combined Spectroscopic and Computational Study	13
Adenine Modification at C7 as a Viable Strategy to Potentiate the Antimalarial Activity of Quinolones	13
Successful Drug Discovery, Volume 5. Edited by János Fischer, Christian Klein, and Wayne E. Childers	13
Discovery of Isatin‐Based Carbohydrazones as Potential Dual Inhibitors of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase	13
Covalent Fragment Screening Identifies Rgl2 RalGEF Cysteine for Targeted Covalent Inhibition of Ral GTPase Activation	12
Sonodynamic Therapy with Metal Complexes: A New Promise in Cancer Therapy	12
Discovery of Quinoline‐Derived Trifluoromethyl Alcohols as Antiepileptic and Analgesic Agents That Block Sodium Channels	12
Effect of meso Positioned Substituents on the Stability and Photodynamic Activity of Lipid‐Membrane‐Incorporated Porphyrin Derivatives	12
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class	12
Medicinal Chemistry for Practitioners. Edited by Jie Jack Li	12
Conception and Evaluation of Fluorescent Phosphine‐Gold Complexes: From Synthesis to in vivo Investigations	12
Structure‐Based Virtual Screening and in vitro and in vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti‐Alzheimer's Agents	12
Front Cover: Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses (ChemMedChem 23/2	12
Cancer‐Mitochondria Dual‐Targeting Glycol/Ferrocenium‐Based Polydopamine Nanoparticles for Synergistic Photothermal and Photodynamic Therapy	12
Mass Spectrometric Assays Reveal Discrepancies in Inhibition Profiles for the SARS‐CoV‐2 Papain‐Like Protease	12
WaterMap‐Guided Structure‐Based Virtual Screening for Acetylcholinesterase Inhibitors	11
Mesoporous Polydopamine‐Based Nanovehicles as a Versatile Drug Loading Platform to Enable Tumor‐Sufficient Synergistic Therapy	11
Front Cover: Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs (ChemMedChem 17/2022)	11
From DC18 to MR07: A Metabolically Stable 4,4′‐Oxybisbenzoyl Amide as a Low‐Nanomolar Growth Inhibitor of P. falciparum	11
Importance of Co‐operative Hydrogen Bonding in the Apramycin‐Ribosomal Decoding A‐Site Interaction	11
Sialic Acid 4‐N‐Piperazine and Piperidine Derivatives Bind with High Affinity to the P. mirabilis Sialic Acid Sodium Solute Symporter	11
Mapping the Melatonin Receptor. 8. Selective MT2 Agonists Derived from 5,6‐Dihydroindolo[2,1‐a]isoquinolines and Related Systems	11
N‐Heterocyclic Carbene (NHC) Silver Complexes as Versatile Chemotherapeutic Agents Targeting Human Topoisomerases and Actin	11
Synthesis of a Bifunctional Cross‐Bridged Chelating Agent, Peptide Conjugation, and Comparison of 68Ga Labeling and Complex Stability Characteristics with Established Chelators	11
Front Cover: The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform‐Selective Inhibitors (ChemMedChem 18/2022)	11
Strategies toward Metal‐Free Carbon Monoxide Prodrugs: An Update	11
Performance of Ir(III)‐Based Anticancer Agents in the Treatment of Cisplatin‐Resistant Cancer Cells	11
Biomolecular Interactions of Cytotoxic Ruthenium Compounds with Thiosemicarbazone or Benzothiazole Schiff Base Chelates	11
Front Cover: Andrographolide Derivatives Target the KEAP1/NRF2 Axis and Possess Potent Anti‐SARS‐CoV‐2 Activity (ChemMedChem 5/2022)	11
Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings	11
Prodrugs of the Archetypal Dynamin Inhibitor Bis‐T‐22	11
Front Cover: Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1 (ChemMedChem 15/2023)	10
Incorporation of Trifluoromethyltriazoline in the Side Chain of 4‐Aminoquinolines: Synthesis and Evaluation as Antiplasmodial Agents	10
Front Cover: Design, Synthesis, and Antiviral Activity of the Thiazole Positional Isomers of a Potent HIV‐1 Entry Inhibitor NBD‐14270 (ChemMedChem 22/2022)	10
Advances in the Analysis of Pharmaceuticals by Using Graphene‐Based Sensors	10

A Critical Study on Acylating and Covalent Reversible Fragment Inhibitors of SARS‐CoV‐2 Main Protease Targeting the S1 Site with Pyridine	10
Front Cover: Carborane Analogues of Fenoprofen Exhibit Improved Antitumor Activity (ChemMedChem 5/2023)	10
Front Cover: Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors (ChemMedChem 6/2023)	10
1‐Indanone and 1,3‐indandione Derivatives as Ligands for Misfolded α‐Synuclein Aggregates	10
Promising Therapeutic Approach for SARS‐CoV‐2 Infections by Using a Rutin‐Based Combination Therapy	10
Lysyl Oxidases as Targets for Cancer Therapy and Diagnostic Imaging	10
Kinase Degraders, Activators, and Inhibitors: Highlights and Synthesis Routes to the Chemical Probes on opnMe.com, Part 1	10
Front Cover: Are Two Riboses Better Than One? The Case of the Recognition and Activation of Adenosine Receptors (ChemMedChem 14/2023)	10
Excited State and Reactive Oxygen Species against Cancer and Pathogens: A Review on Sonodynamic and Sono‐Photodynamic Therapy	10
Hepatic‐Targeted Nano‐enzyme with Resveratrol Loading for Precise Relief of Nonalcoholic Steatohepatitis	10
An Active Member of the EFMC: The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society**	9
hERG Optimization of Benzofuro−Pyridine and Pyrazino−Indole Derivatives as MCHR1 Antagonists	9
New Indole‐Based Phenylthiazolyl‐2,4‐dihydropyrazolones as Tubulin polymerization inhibitors: Multicomponent Synthesis, Cytotoxicity Evaluation, and in silico Studies	9
α‐Triazolylboronic Acids: A Novel Scaffold to Target FLT3 in AML	9
Promoting GAINs (Give Attention to Limitations in Assays) over PAINs Alerts: no PAINS, more GAINs	9
Design, Synthesis and Biological Evaluation of Histone Deacetylase Inhibitors Based on Pyrrolo[2,3‐d]pyrimidine and Pyrrolo[2,3‐b]pyridine Scaffolds	9
A Single‐Atom Nanozyme Cascade for Selective Tumor‐Microenvironment‐Responsive Nanocatalytic Therapy	9
Scouting Different Phosphodiesterase 4 Inhibitor Chemotypes in Silico To Guide the Design of Anti‐inflammatory/Antioxidant Agents	9
CYP3A4 Catalyzes the Rearrangement of the Dual Orexin Receptor Antagonist Daridorexant to 4‐Hydroxypiperidinol Metabolites	9
Synthesis and Biological Activity of 2‐Benzo[b]thienyl and 2‐Bithienyl Amidino‐Substituted Benzothiazole and Benzimidazole Derivatives	9
CORRIGENDUM: α‐Triazolylboronic Acids: A Novel Scaffold to Target FLT3 in AML	9
Biocatalytic Amino Acid Functionalisation	9
Carbon‐13 Hyperpolarization of α‐Ketocarboxylates with Parahydrogen in Reversible Exchange	9
Development of LpxH Inhibitors Chelating the Active Site Dimanganese Metal Cluster of LpxH	9
Discovery of Novel 2‐Oxindoles as Compounds with Antiglaucoma Activity	9
Anthraquinone‐Based Ligands as MNase Inhibitors: Insights from Inhibition Studies and Generation of a Payload Nanocarrier for Potential Anti‐MRSA Therapy	9
Terpyridine Glycoconjugates and Their Metal Complexes: Antiproliferative Activity and Proteasome Inhibition	9
Carborane‐Based Tebufelone Analogs and Their Biological Evaluation In Vitro	9
Front Cover: Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein (ChemMedChem 10/2023)	9
Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1	9
Significant Tumor Inhibition of Trimethyl‐152‐[L‐aspartyl]pheophorbide a in Tumor Photodynamic Therapy‡	9
Design and Synthesis of Fsp3‐Enriched Spirocyclic‐Based Biological Screening Compound Arrays via DOS Strategies and Their NNMT Inhibition Profiling	9
Synthesis, Characterization and in vitro Anticancer Evaluation of 5‐Sulfinyl(sulfonyl)‐4‐arylsulfonyl‐Substituted 1,3‐Oxazoles	9
Metal‐Catalyzed Cross‐Coupling for the Synthesis of β‐Lactam Drugs and Related Chemical Probes	9
Front Cover: Terpyridine Glycoconjugates and Their Metal Complexes: Antiproliferative Activity and Proteasome Inhibition (ChemMedChem 7/2023)	9
Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction–Optimization Strategy Applied to Paullones	9
Isopeptidic Desferrioxamine Analogues: The Role of Hydroxamate Spacing for Chelation of Zr4+	8
Prospects and Challenges of Developing Plant‐Derived Snake Antivenin Natural Products: A Focus on West Africa	8
Inhibitory Effect of Salicin on Staphylococcus aureus Coagulase	8
Discovery of Novel Pyrido[2,3‐b]Pyrazine Human Cytomegalovirus Polymerase Inhibitors with Broad Spectrum Antiherpetic Activity and Reduced hERG Inhibition	8
Inhibitors of Aspartate Transcarbamoylase Inhibit Mycobacterium tuberculosis Growth	8
Investigating the C2 Modulation of the Imidazo[1,2‐a]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition	8
Recent Development of Copper (II) Complexes of Polypyridyl Ligands in Chemotherapy and Photodynamic Therapy	8
Development of Benzimidazole‐Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies	8
DprE1 Inhibitors: Enduring Aspirations for Future Antituberculosis Drug Discovery	8
Design of Dual EP2/EP4 Antagonists through Scaffold Merging of Selective Inhibitors	8
Advances in Diclofenac Derivatives: Exploring Carborane‐Substituted N‐Methyl and Nitrile Analogs for Anti‐Cancer Therapy	8
Insight into Stabilization of G‐Quadruplex in c‐MYC Region with Phenanthroimidazoisoindol‐Acrylates and their Binding Behaviour towards Human Serum Albumin	8
Metal‐Based Aggregation‐Induced Emission Theranostic Systems	8
Developing Dynamic Structure‐Based Pharmacophore and ML‐Trained QSAR Models for the Discovery of Novel Resistance‐Free RET Tyrosine Kinase Inhibitors Through Extensive MD Trajectories and NRI Analysis	8
Step‐Economical Mechanosynthesis of Hybrid Azoles: Deciphering Their π‐Orbital and Pharmacological Characteristics	8
Optimization of Ketobenzothiazole‐Based Type II Transmembrane Serine Protease Inhibitors to Block H1N1 Influenza Virus Replication	8
C7‐Halomethylene/methyl‐C3‐thiophenyl‐spirocyclic‐β‐lactams: Synthesis, X‐ray Analysis, Antimicrobial Evaluation, Cytotoxicity Profile and Molecular Docking Interactions	8
Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design	8
Application of Phosphoramidate ProTide Technology for the Synthesis of 5’‐mRNA Cap Analogs Modified on the Exocyclic Amine Group	8
Chimeric Amphiphilic Disinfectants: Quaternary Ammonium/Quaternary Phosphonium Hybrid Structures	8
	8
Current Approaches and Strategies Applied in First‐in‐class Drug Discovery	8
Improving Affinity while Reducing Kidney Uptake of CXCR4‐Targeting Radioligands Derived from the Endogenous Antagonist EPI‐X4	8
Copper and Copper Complexes in Tumor Therapy	8
Prediction of Chameleonic Efficiency	8
Synthesis and Carbonic Anhydrase I, II, IX, and XII Inhibition Studies with a Series of Cyclic Sulfonyl Guanidines	8
The Role of Protein Disulfide Isomerase Inhibitors in Cancer Therapy	8
Design and Synthesis of 1,3‐Diynes as Potent Antifungal Agents against Aspergillus fumigatus	8
Anticancer Activities of Tetrasubstituted Imidazole‐Pyrimidine‐Sulfonamide Hybrids as Inhibitors of EGFR Mutants	8
Nicorandil repurposing in orofacial pain: preclinical findings in adult zebrafish	8
Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies	8
Autophagy‐Mediated Targeted Protein Degradation	8
Peptides Corresponding to the Receptor‐Binding Domain (RBD) of Several SARS‐CoV‐2 Variants Of Concern Prevent Recognition of the Human ACE2 Receptor and Consecutive Cell Infections	7
Discovery of an L‐like Configuration for 3’‐Fluoro‐5’‐norcarbonucleoside Phosphonates as Potent Anti‐HIV Agents	7
	7
Exploring Raloxifene‐Based Metallodrugs: A Versatile Vector Combined with Platinum(II), Palladium(II) and Nickel(II) Dichlorides and Carborates against Triple‐Negative Breast Cancer	7
Neuroblastoma and its Target Therapies: A Medicinal Chemistry Review	7
Silicon Phthalocyanines Functionalized with Axial Substituents Targeting PSMA: Synthesis and Preliminary Assessment of Their Potential for PhotoDynamic Therapy of Prostate Cancer	7
A Potent N‐(piperidin‐4‐yl)‐1H‐pyrrole‐2‐carboxamide Inhibitor of Adenylyl Cyclase of G. lamblia: Biological Evaluation and Molecular Modelling Studies	7
Exploring the Chemical Space of Mycobacterial Oxidative Phosphorylation Inhibitors Using Molecular Modeling	7
Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS)	7
	7
The Aggregates of Near‐Infrared Cyanine Dyes in Phototherapy	7
Discovery of a Dual‐Target Inhibitor of CDK7 and HDAC1 That Induces Apoptosis and Inhibits Migration in Colorectal Cancer**	7
Methods for the Generation of Single‐Payload Antibody‐Drug Conjugates	7
Structure and Activity of Reconstructed Pseudo‐Ancestral Cyclotides	7
A Dual Action Platinum(IV) Complex with Self‐assembly Property Inhibits Prostate Cancer through Mitochondrial Stress Pathway	7
Front Cover: Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolo[1,5‐a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis (C	7
Self‐Assembling Peptide‐Based High‐Relaxivity Targeted MRI Contrast Agents	7
Front Cover: Identification of ß‐Glucocerebrosidase Activators for Glucosylceramide hydrolysis (ChemMedChem 7/2024)	7
Isoniazid‐Dihydropyrimidinone Molecular Hybrids: Design, Synthesis, Antitubercular Activity and Cytotoxicity Investigations with Computational Validation	7
Synthesis and Antiproliferative Evaluation of d‐Glucuronamide‐Based Nucleosides and (Triazolyl)methyl Amide‐Linked Pseudodisaccharide Nucleosides**	7
	7
The Wheel of Fortune: Helical Wheel Alanine Scanning of a Spider Venom Antimicrobial Peptide Reveals Residues Involved in Antimicrobial and Cytotoxic Activity	7
Corrigendum: Design of Trehalose‐Based Amide/Sulfonamide C‐type Lectin Receptor Signaling Compounds	7
Analogues of Natural Macarangin B Display Potent Antiviral Activity and Better Metabolic Stability	7
Design, Synthesis of (±)‐Millpuline A, and Biological Evaluation for the Lung Cell Protective Effects through SRC	7
Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolo[1,5‐a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis**	7
Targeting Tumor‐Associated Carbonic Anhydrases in Photothermal Therapy	7