OOIR: Observatory of International Research

Papers

(The median citation count of Cellular and Molecular Bioengineering is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Acteoside-Loaded Self-Healing Hydrogel Enhances Skin Wound Healing through Modulation of Hair Follicle Stem Cells	436
Probing the Effects of Chirality on Self-Assembling Peptides: Hydrogel Formation, Degradation, Antigen Release, and Adjuvancy	165
Formins and Arp2/3 Reciprocally Regulate Contact Guidance on Aligned Collagen Fibrils	32
Graph-Based Spatial Proximity of Super-Resolved Protein–Protein Interactions Predicts Cancer Drug Responses in Single Cells	25
Causative Role of Anoxic Environment in Bacterial Regulation of Human Intestinal Function	25
An Electromechanical Model-Based Study on the Dosage Effects of Ranolazine in Treating Failing HCM Cardiomyocyte	24
FGF-2–Overexpressing Adipose-Derived Stem Cells as a Paracrine Platform for Angiogenesis-Driven Tissue Regeneration	20
Sevoflurane Suppresses the Proliferation, Migration and Invasion of Colorectal Cancer Through Regulating Circ_0000423/miR-525-5p/SGPP1 Network	19
CRISPR-dCas9 Activation of TSG-6 in MSCs Modulates the Cargo of MSC-Derived Extracellular Vesicles and Attenuates Inflammatory Responses in Human Intervertebral Disc Cells In Vitro	18
Relatively Rare Populations of Invasive Cells Drive Progression of Heterogeneous Tumors	16
Endothelial Cells Stably Infected with Recombinant Kaposi’s Sarcoma-Associated Herpesvirus Display Distinct Viscoelastic and Morphological Properties	15
Simulation of Somatic Evolution Through the Introduction of Random Mutation to the Rules of Conway’s Game of Life	14
Amelotin Promotes Mineralization and Adhesion in Collagen-Based Systems	14
Paracrine Signaling by Distinct Adipose Tissue Depots Regulate Fibroblast Mechanobiology and Functional Heterogeneity	14
Based on Medicine, The Now and Future of Large Language Models	12
Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity	12
Engineered Extracellular Vesicle-Based Therapies for Valvular Heart Disease	12
A 3D Human Lymphatic Vessel-on-Chip Reveals the Roles of Interstitial Flow and VEGF-A/C for Lymphatic Sprouting and Discontinuous Junction Formation	11
A Label-Free Colorimetric AuNP-Aptasensor for the Rapid Detection of Vibrio cholerae O139	11
Caveolin Delivered by Ultrasound-Mediated Microbubble Destruction Prevents Endothelial Cell Proliferation	11
Bio-adhesive Macroporous Hydrogels for In Situ Recruitment and Modulation of Dendritic Cells	10
A Conversation on Artificial Intelligence, Chatbots, and Plagiarism in Higher Education	10
THP-1 Macrophages Limit Neutrophil Transendothelial Migration in a Model Infection	9
Investigation of the Therapeutic Effects of Palbociclib Conjugated Magnetic Nanoparticles on Different Types of Breast Cancer Cell Lines	9
Magnetoactive, Kirigami-Inspired Hammocks to Probe Lung Epithelial Cell Function	9

The 2023 Young Innovators of Cellular and Molecular Bioengineering	8
The 2025 Young Innovators of Cellular and Molecular Bioengineering	8
siRNA Lipid–Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therapy	8
A Vascularized Human Organ Chip Reveals SARS-CoV-2 Susceptibility in Developmentally Guided Tissue Maturation	8
Elucidating Mechanotransduction Processes During Magnetomechanical Neuromodulation Mediated by Magnetic Nanodiscs	8
Fetal Bovine Serum Modulates Primary Human Cell Phenotypes, Endothelial Barrier Function, Vasculogenesis, and Angiogenesis in a Sex-Specific Manner	7
Agent-Based Models Help Interpret Patterns of Clinical Drug Resistance by Contextualizing Competition Between Distinct Drug Failure Modes	7
Matrix Stiffness-Mediated DNA Methylation in Endothelial Cells	7
Influence of Hematocrit Level and Integrin αIIbβIII Function on vWF-Mediated Platelet Adhesion and Shear-Induced Platelet Aggregation in a Sudden Expansion	7
G Protein-Coupled Estrogen Receptor Regulates Mesenchymal Stem Cell Mechanotransduction and Differentiation	7
Hypoxic Preconditioned ADSC Exosomes Enhance Vaginal Wound Healing via Accelerated Keratinocyte Proliferation and Migration Through AKT/HIF‑1α Axis Activation	7
Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport	7
Circ_0004585 Facilitates Tumorigenesis of Colorectal Cancer Via Modulating the miR-338-3p/ZFX Axis and Activating the MEK/ERK Pathway	7
Enhancing Neurological Competence of Nanoencapsulated Cordyceps/Turmeric Extracts in Human Neuroblastoma SH-SY5Y Cells	6
Examining the Effects of Quercetin on Phenotypic Characteristics of Human Mesenchymal Stem Cells	6
Theoretical and Experimental Studies of the Dynamic Damage of Endothelial Cellular Networks Under Ultrasound Cavitation	6
Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status	6
Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease	6
Tumor-Targeting Extracellular Vesicles Loaded with siS100A4 for Suppressing Postoperative Breast Cancer Metastasis	6
Surface-Engineered Mitochondria with Targeting Potential for Endothelial Repair	5
Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk Using QCM-D	5
Analysis of Regional Variations of the Interstitial Cells of Cajal in the Murine Distal Stomach Informed by Confocal Imaging and Machine Learning Methods	5
Pathological Features of Colorectal Adenocarcinoma Patients Related to MLH1	5
Trisomy 21 Alters Cell Proliferation and Migration of iPSC-Derived Cardiomyocytes on Type VI Collagen	5
Enhancing Pluripotency and Adipogenic Differentiation in Human Adipose Tissue-Derived Stem Cells Through miR-302/367 Cluster Overexpression	5
The 2023 CMBE Young Innovators: ChatGPT Gets the Final Word	5
Cellular and Molecular Bioengineering: At the Nexus with the Next Editor-in-Chief	5
Development of Serum-Free Media for Cryopreservation of Hydrogel Encapsulated Cell-Based Therapeutics	5
Stiffer-Matrix-Induced PGC-1α Upregulation Enhanced Mitochondrial Biogenesis and Oxidative Stress Resistance in Non-small Cell Lung Cancer	5
Hyaluronic Acid-Coated Melt Electrowritten Scaffolds Promote Myoblast Attachment, Alignment, and Differentiation	5
Myosin II Adjusts Motility Properties and Regulates Force Production Based on Motor Environment	5
Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis	5
High-Density Branched PEGylation for Nanoparticle Drug Delivery	5
Three-Dimensional Fractal Analysis of the Interstitial Cells of Cajal Networks of Gastrointestinal Tissue Specimens	4
A New Bacterial Chassis for Enhanced Surface Display of Recombinant Proteins	4
A Multicellular Mechanochemical Model to Investigate Tumor Microenvironment Remodeling and Pre-Metastatic Niche Formation	4
Intracellular Macromolecular Crowding within Individual Stress Fibers Analyzed by Fluorescence Correlation Spectroscopy	4
Characterization of diffusivity and mechanical properties of polyethylene glycol hydrogel conformal coatings over time for application in beta cell replacement therapy for type 1 diabetes	4
Single-Cell Proliferation Microfluidic Device for High Throughput Investigation of Replicative Potential and Drug Resistance of Cancer Cells	4
Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure	4
Encapsulation of Manganese Porphyrin in Chondroitin Sulfate-A Microparticles for Long Term Reactive Oxygen Species Scavenging	4
Incorporation of ChatGPT and Other Large Language Models into a Graduate Level Computational Bioengineering Course	4
Strain Promotes Triple Negative Breast Cancer Proliferation and Migration Via VEGFR-2	3
Empowering High-Throughput High-Content Analysis of Microphysiological Models: Open-Source Software for Automated Image Analysis of Microvessel Formation and Cell Invasion	3
Altered Caveolin-1 Dynamics Result in Divergent Mineralization Responses in Bone and Vascular Calcification	3
Effects of FTY720 on Neural Cell Behavior in Two and Three-Dimensional Culture and in Compression Spinal Cord Injury	3
Exploring the Causes of Intervertebral Disc Annulus Fibrosus Impairment	3
Correction: Innovation and Entrepreneurship in Promotion and Tenure in Biomedical Engineering	3
Assessing the Effects of Dasatinib on Mesenchymal Stem/Stromal Cells	3
YIGSR, A Laminin-Derived Peptide, Dictates a Concentration-Dependent Impact on Macrophage Phenotype Response	3

Disrupted Sarcomere Reorganization of Cardiomyopathy-Prone Human iPSC-Derived Cardiomyocytes on a Dynamic Mechanical Substrate	3
Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors	2
Contact Guidance Drives Upward Cellular Migration at the Mesoscopic Scale	2
Light Activates Cdc42-Mediated Needle-Shaped Filopodia Formation via the Integration of Small GTPases	2
Uncovering Cellular Interactome Drivers of Immune Checkpoint Inhibitor Response in Advanced Melanoma Patients	2
Multiomic Integration Reveals Taxonomic Shifts Correlate to Serum Cytokines in an Antibiotics Model of Gut Microbiome Disruption	2
Optogenetic Modulation of Arrhythmia Triggers: Proof-of-Concept from Computational Modeling	2
Empowering High Throughput Screening of 3D Models: Automated Dispensing of Cervical and Endometrial Cancer Cells	2
The 2022 Young Innovators of Cellular and Molecular Bioengineering	2
Artificial Intelligence, Chatbots, Plagiarism and Basic Honesty: Comment	2
Angiotensin II Increases Oxidative Stress and Inflammation in Female, But Not Male, Endothelial Cells	2
Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance	2
Amelioration of Subglottic Stenosis by Antimicrobial Peptide Eluting Endotracheal Tubes	2
Plant Tissue Parenchyma and Vascular Bundles Selectively Regulate Stem Cell Mechanosensing and Differentiation	2
TNF-α Preconditioning Promotes a Proangiogenic Phenotype in hiPSC-Derived Vascular Smooth Muscle Cells	2
An Integrative Biology Approach to Quantify the Biodistribution of Azidohomoalanine In Vivo	2
Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy	2
Organoids as Sophisticated Tools for Renal Cancer Research: Extensive Applications and Promising Prospects	2
P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress	2
Minimally-Invasive and Efficient Method to Accurately Fit the Bergman Minimal Model to Diabetes Type 2	2