OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical Epigenetics is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Psychostimulant-induced aberrant DNA methylation in an in vitro model of human peripheral blood mononuclear cells	153
Integrative genomics analysis of nasal intestinal-type adenocarcinomas demonstrates the major role of CACNA1C and paves the way for a simple diagnostic tool in male woodworkers	152
DNA methylation patterns associated with konzo in Sub-Saharan Africa	118
Novel genetic variants of KHDC3L and other members of the subcortical maternal complex associated with Beckwith–Wiedemann syndrome or Pseudohypoparathyroidism 1B and multi-locus imprinting disturbance	86
Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients	78
Disrupted methylation patterns at birth persist in early childhood: a prospective cohort analysis	62
Novel epigenetic network biomarkers for early detection of esophageal cancer	61
Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers	60
Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance	54
Multi-omic alterations of the SWI/SNF complex define a clinical subgroup in lung adenocarcinoma	53
Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival	51
An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study	51
Epigenetic adaptations of the masticatory mucosa to periodontal inflammation	46
Aberrant epigenetic and transcriptional events associated with breast cancer risk	44
Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer	42
Defining post-acute COVID-19 syndrome (PACS) by an epigenetic biosignature in peripheral blood mononuclear cells	42
Whole blood methylome-derived features to discriminate endocrine hypertension	40
Cross talk between acetylation and methylation regulators reveals histone modifier expression patterns posing prognostic and therapeutic implications on patients with colon cancer	39
DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application	38
Validating biomarkers and models for epigenetic inference of alcohol consumption from blood	36
First step towards a consensus strategy for multi-locus diagnostic testing of imprinting disorders	35
Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy	33
Fetal exposure to phthalates and bisphenols and DNA methylation at birth: the Generation R Study	33
Predicting disease-free survival in colorectal cancer by circulating tumor DNA methylation markers	33
Maternal epigenetic clocks measured during pregnancy do not predict gestational age at delivery or offspring birth outcomes: a replication study in metropolitan Cebu, Philippines	33

Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)	32
Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back pain	32
Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro dat	31
Plasma lipid profiles in early adulthood are associated with epigenetic aging in the Coronary Artery Risk Development in Young Adults (CARDIA) Study	31
Epigenome-wide association studies: current knowledge, strategies and recommendations	30
Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach	30
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer	30