Clinical Epigenetics

Papers
(The TQCC of Clinical Epigenetics is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Disrupted methylation patterns at birth persist in early childhood: a prospective cohort analysis104
DNA methylation patterns associated with konzo in Sub-Saharan Africa89
Psychostimulant-induced aberrant DNA methylation in an in vitro model of human peripheral blood mononuclear cells85
Novel genetic variants of KHDC3L and other members of the subcortical maternal complex associated with Beckwith–Wiedemann syndrome or Pseudohypoparathyroidism 1B and multi-locus imprinting disturbance76
Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers64
Novel epigenetic network biomarkers for early detection of esophageal cancer62
Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients56
An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study53
Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer43
Defining post-acute COVID-19 syndrome (PACS) by an epigenetic biosignature in peripheral blood mononuclear cells41
Multi-omic alterations of the SWI/SNF complex define a clinical subgroup in lung adenocarcinoma41
Aberrant epigenetic and transcriptional events associated with breast cancer risk40
Cross talk between acetylation and methylation regulators reveals histone modifier expression patterns posing prognostic and therapeutic implications on patients with colon cancer39
Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival39
Whole blood methylome-derived features to discriminate endocrine hypertension37
Maternal epigenetic clocks measured during pregnancy do not predict gestational age at delivery or offspring birth outcomes: a replication study in metropolitan Cebu, Philippines37
Predicting disease-free survival in colorectal cancer by circulating tumor DNA methylation markers35
Plasma lipid profiles in early adulthood are associated with epigenetic aging in the Coronary Artery Risk Development in Young Adults (CARDIA) Study34
Circulating cell-free DNA methylation mirrors alterations in cerebral patterns in epilepsy33
Genome-wide distribution of histone trimethylation reveals a global impact of bisphenol A on telomeric binding proteins and histone acetyltransferase factors: a pilot study with human and in vitro dat32
First step towards a consensus strategy for multi-locus diagnostic testing of imprinting disorders31
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)31
Epigenome-wide DNA methylation profiling of conditioned pain modulation in individuals with non-specific chronic low back pain30
Fetal exposure to phthalates and bisphenols and DNA methylation at birth: the Generation R Study30
Epigenome-wide contributions to individual differences in childhood phenotypes: a GREML approach29
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer29
Epigenome-wide association study of lung function in Latino children and youth with asthma28
Dynamic patterns of blood lipids and DNA methylation in response to statin therapy28
Maternal–fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study28
Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms27
Altered DNA methylation in estrogen-responsive repetitive sequences of spermatozoa of infertile men with shortened anogenital distance27
Epigenetics of early-life adversity in youth: cross-sectional and longitudinal associations25
Epigenetics of type 2 diabetes and diabetes-related outcomes in the Strong Heart Study25
Association of nutritional glycaemic indices with global DNA methylation patterns: results from the Moli-sani cohort25
OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorder25
Integrated 5-hydroxymethylcytosine and fragmentation signatures as enhanced biomarkers in lung cancer24
Decreased mitochondrial D-loop region methylation mediates an increase in mitochondrial DNA copy number in CADASIL23
Identification of differentially methylated regions in rare diseases from a single-patient perspective23
The emerging role of epigenetic regulation in the progression of silicosis23
Bisulfite profiling of the MGMT promoter and comparison with routine testing in glioblastoma diagnostics23
A randomized, phase II trial of oral azacitidine (CC-486) in patients with resected pancreatic adenocarcinoma at high risk for recurrence22
Correction to: ZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer22
Why epigenetics is (not) a biosocial science and why that matters22
Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder21
Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature21
Investigating pathological epigenetic aberrations by epi-proteomics20
JIB-04, a histone demethylase Jumonji C domain inhibitor, regulates phenotypic switching of vascular smooth muscle cells20
Lifetime exposure to smoking, epigenetic aging, and morbidity and mortality in older adults20
Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis19
Integrated multi-omics analyses reveal that BCAM is associated with epigenetic modification and tumor microenvironment subtypes of clear cell renal cell carcinoma19
Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer19
Serum level of total histone 3, H3K4me3, and H3K27ac after non-emergent cardiac surgery suggests the persistence of smoldering inflammation at 3 months in an adult population19
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