Anti-Cancer Agents in Medicinal Chemistry

Article	Citations
Synthesis and in vitro Anti-proliferative Activities on LNCaP, LS180 and MKN45 of Novel 20(R)-Panaxadiol Derivatives	147
Preface	84
Design, Synthesis, In vitro and In vivo Evaluation of New Imidazo[1,2-a]pyridine Derivatives as Cyclooxygenase-2 Inhibitors	79
Processed Products of Aconitum soongaricum Stapf. Inhibit the Growth of Ovarian Cancer Cells In vivo via Regulating the PI3K/AKT Signal Pathway	61
Construction of Biomimetic-Responsive Nanocarriers and their Applications in Tumor Targeting	47
The Effect of Iron Oxide Nanoparticles of Acalypha wilkesiana Ethyl Acetate Extract on Ehrlich Ascites Carcinoma Cells	44
Berberine Hydrochloride Inhibits the Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells by Regulating Amino Acid Metabolism	36
An Updated Insight into the Phytomolecules Reported for the Treatment of Colon Cancer from 2015 to 2024	30
Unveiling the Potential of S4 on Non-small Cell Lung Cancer Cells: Impact on Proliferation, Apoptosis, Senescence, and Metabolome Profile	30
Decoding Sarcoma Drug Resistance: From Molecular Mechanisms to Precision Interventions	30
Timosaponin A-III Induces ROS-mediated Apoptosis and Triggers Protective Autophagy via the AMPK/mTOR Pathway in Prostate Cancer	29
Diterpenoid Tanshinone Attenuates the Metastasis of Non-small-cell Lung Cancer (NSCLC) Cells by Inhibiting the Cavin-1-mediated ERK/Smad2 Signaling Pathway	29
The Importance of Structural Water in HDAC8 for Correct Binding Pose Applied for Drug Design of Anticancer Molecules	28
Design, Synthesis and Biological Evaluation of New 4-(4-(Methylsulfonyl) Phenyl)-6-Phenylpyrimidin-2-Amine Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors	28
Design, Synthesis, Antimicrobial and Antitumor Activities of Benzo[f]chromene Derivatives: DFT and Molecular Docking	26
CYP1B1: A Promising Target in Cancer Drug Discovery	26
Preface	25
Retracted: Anti-proliferative, Morphological and Molecular Docking Studies of New Thiophene Derivatives and their Strategy in Ionic Liquids Immobilized Reactions	25
Effects of Arctigenin in Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma 5-8F Cells	25
Anticancer Potential of Eudesmanolides Derived from Sphagneticola trilobata against Colorectal Cancer, by Targeting β-catenin Signalling	24
Innovative Nanocarriers: Magnetosomes in the Fight against Cancer	24
MDM2-mediated Inhibitory Effect of Arsenic Trioxide on Small Cell Lung Cancer Cell Line by Degrading Mutant p53	23
Recent Advancement in the Inhibition of Triple-negative Breast Cancer by N-heterocycles	23
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells	23
Enhanced Apoptosis in Pancreatic Cancer Cells through Thymoquinone-rich Nigella sativa L. Methanol Extract: Targeting NRF2/HO-1 and TNF-α Pathways	21

The Combination of Chrysin and Cisplatin Induces Apoptosis in HepG2 through Down-regulation of cFLIP and Activity of Caspase	21
Determination of Pralsetinib in Human Plasma and Cerebrospinal Fluid for Therapeutic Drug Monitoring by Ultra-performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)	21
Anti-Tumor and Anti-Metastasis Effects of Berbamine-Loaded Lipid Nanoparticles on Pancreatic Cancer	21
HSP Inhibitor Sensitize Resistant MCF-7 Cells to Doxorubicin through Suppressing HSP90AB4P Pseudogene and HSPB1 Expression	20
dHG-5 Exhibits Dual Efficacy of Anti-Metastatic and Anti-hypercoagulability in Mice by Inhibiting Heparanase and Intrinsic Coagulation Pathway	20
PHD-BAH Domain in ASH1L Could Recognize H3K4 Methylation and Regulate the Malignant Behavior of Cholangiocarcinoma	19
Natural Combatants: How Herbal Monomers Regulate Autophagy in Ovarian Cancer	19
Polyphenols as the Potential Disease-modifying Therapy in Cancer	18
Synthesis of New Pyrazole Hybrids as Potential Anticancer Agents with Xanthine Oxidase Inhibitory Activity	18
1,3-Diaryl Triazenes Incorporating Disulfonamides Show Both Antiproliferative Activity and Effective Inhibition of Tumor-associated Carbonic Anhydrases IX and XII	18
QSAR Research of Novel Tetrandrine Derivatives against Human Hepatocellular Carcinoma	18
Melatonin Enhances Anti-tumoral Effects of Menadione on Colon Cancer Cells	18
Design, Synthesis, and Apoptosis-Promoting Effect Evaluation of Chalcone Derivatives Containing Aminoguanidine Units	18
Molecular Activities and Mechanisms of Action of Substances and Molecules from Medicinal Plants from Sub-Saharan Africa on Prostate and Cervical Cancer Cells	17
A Preliminary Study on Photodynamic Therapy for Central Tracheobronchial Malignant Tumours	17
Unveiling the Therapeutic Potential of Trigonelline: A Promising Approach in Cancer Prevention and Treatment	17
Antidepressant Sertraline Hydrochloride Inhibits the Growth of HER2+ AU565 Breast Cancer Cell Line through Induction of Apoptosis and Cell Cycle Arrest	17
Doramectin Induces Apoptosis in B16 Melanoma Cells	17
WITHDRAWN: Monochasma savatieri Inhibits the Migration of the Breast Cancer Cell Line MDA-MB-231	17
Profiling Extrachromosomal Circular DNA (ecDNA) in Cancer via Next-Generation Sequencing: A New Frontier in Tumor Evolution and Therapy Resistance	17
Molecular Targets of Plant-based Alkaloids and Polyphenolics in Liver and Breast Cancer- An Insight into Anticancer Drug Development	16
Apoptosis-inducing Metabolite from Marine Mangrove Actinobacteria VITGAP173	16
ADME Prediction, Structure-activity Relationship of Boswellic Acid Scaffold for the Aspect of Anticancer & Anti-inflammatory Potency	16
Heterocyclic Compounds: Importance in Anticancer Drug Discovery	16
Design and Development of Triazole Derivatives as Prospective Anticancer Agents: A Review	15
3-Bromopyruvate Inhibits the Growth and Glucose Metabolism of TNBC Xenografts in Nude Mice by Targeting c-Myc	15
Revealing the Role of the Arg and Lys in Shifting Paradigm from BTK Selective Inhibition to the BTK/HCK Dual Inhibition - Delving into the Inhibitory Activity of KIN-8194 against BTK, and HCK in the T	15
Maternal Embryonic Leucine Zipper Kinase (MELK) as a Promising Therapeutic Target in Triple Negative Breast Cancer	15
Quercetin-based Nanoformulation: A Potential Approach for Cancer Treatment	15
Meet the Section Editor	15
ALK and ERBB2 Protein Inhibition is Involved in the Prevention of Lung Cancer Development by Vincamine	15
Primary Pulmonary Lymphoepithelioma-like Carcinoma: A Case Report Utilizing Camrelizumab and Anlotinib for Prolonged Survival	14
Natural Products and Gastric Cancer: Cellular Mechanisms and Effects to Change Cancer Progression	14
Agrimonolide Inhibits the Malignant Progression of Non-small Cell Lung Cancer and Induces Ferroptosis through the mTOR Signaling Pathway	14
An Outlook of the Structure Activity Relationship (SAR) of Naphthalimide Derivatives as Anticancer Agents	14
Targeting Glutamine Metabolism through Glutaminase Inhibition Suppresses Cell Proliferation and Progression in Nasopharyngeal Carcinoma	14
Newly Synthesized Benzimidazoles Inhibit Vascular Endothelial Growth Factor and Matrix Metalloproteinase-2 and -9 Levels in Prostate Cancer Cells	14
Synthesis and Biological Studies of Aurones Derivatives for its Anticancer Potential	14
Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from Nigella sativa L.	14
HLTF Promotes the Proliferation of Osteosarcoma Cells and Cisplatin Resistance	14
Chemical Characterization, In-silico Evaluation, and Molecular Docking Analysis of Antiproliferative Compounds Isolated from the Bark of Anthocephalus cadamba Miq.	14
Tisotumab Vedotin: The First FDA-Approved Antibody-Drug Conjugate for Cervical Cancer	14
Bakuchiol: A Potential Anticancer Compound from Psoralea corylifolia Linn	13
Luteolin Enhances Anticancer Effects of PX-478 during Hypoxic Response in Metastatic Breast Cancer Cells	13
Precision Therapy for Prostate Cancer: Advancements in Polymeric Nanocarrier Systems	13
Oxygen Free Radicals and Cancer: Protective Role of Endogenous Antioxidants and Natural Compounds	13
Advances in VEGFR Inhibitors: A Comprehensive Review of Novel Anticancer Agents	13
Matrix Metalloproteinases in Oral Cancer Pathogenesis and their Use in Therapy	13
Eco-friendly Synthesis and Characterization of Silver Nanoparticles using Juglans regia Extract and their Anti-Trichomonas vaginalis, Anticancer, and Antimicrobial Effects	13
Gastrodin Attenuates Colitis and Prevents Tumorigenesis in Mice by Interrupting TLR4/MD2/NF-κB Signaling Transduction	13

Preclinical Evaluation of the Methyl (Z)-2-(isothioureidomethyl)-2-pentenoate Hydrobromide: Antitumor Efficacy and Safety Profile in a Murine Melanoma Model	13
Cytotoxic Evaluation and Molecular Docking Studies of Aminopyridine Derivatives as Potential Anticancer Agents	12
Karanjin, A Promising Bioactive Compound Possessing Anti-cancer Activity against Experimental Model of Non-small Cell Lung Cancer Cells	12
Royal Jelly's Strong Selective Cytotoxicity Against Lung Malignant Cells and Macromolecular Alterations in Cells Observed by FTIR Spectroscopy	12
Overexpression of Bromodomain and Extraterminal Domain is Associated with Progression, Metastasis and Unfavorable Outcomes: Highlighting Prognostic and Therapeutic Value of the BET Protein Family in G	12
Innovative Therapies for Oncogenic KRAS Mutations: Precision Strategies with PROTACs in Cancer Treatment	11
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription	11
Trailing TRAIL Resistance in Human Breast Adenocarcinoma Cells with Trichostatin A and Zebularine	11
Unveiling the Vital Role of ACTA2-AS1 in Human Cancers: Molecular Mechanisms and Clinical Applications	11
New Frontiers in the Discovery and Development of PROTACs	11
Curcumin and its Analogues in Oral Squamous Cell Carcinoma: State-of-the-art and Therapeutic Potential	11
Retraction Notice to "The Natural Flavonoid Naringenin Inhibits the Cell Growth of Wilms Tumor in Children by Suppressing TLR4/NF-κB Signaling"	11
Lupiwighteone as an Antitumor Agent Reverses Multidrug Resistance in K562/ADR Cells by Regulating Cellular Prion Protein-Oct4 Axis	11
S16020 Pyridocarbazole Derivatives Display High Activity to Lung Cancer Cells	11
Pomegranate Oil Nanoemulsion as a Nanotherapeutic Strategy Against Breast and Colon Cancer: Induction of Apoptosis and Inhibition of Cell Migration	11
Synergism Effect of Dendrobine on Cisplatin in Treatment of H1299 by Modulating the Balance of Treg/Th17	11
Liposomal Drug Delivery and Its Potential Impact on Cancer Research	11
Corrigendum to: “An Overview of Conventional Drugs and Nanotherapeutic Options for the Treatment and Management of Pediatric Acute Lymphoblastic Leukemia”	11
Antibody Drug Conjugates (ADCs): Shaping the Future of Precision Oncology	10
Novel Synthetic Indazoles Abrogate Angiogenesis in Erlich Ascites Tumor Bearing Mice	10
Baicalin Inhibits Lung Cancer Cell Proliferation and Migration via ALOX12-Mediated Ferroptosis	10
A Green Synthesis of Au-Ag Alloy Nanoparticles using Polydopamine Chemistry: Evaluation of their Anticancer Potency Towards Both MCF-7 Cells and their Cancer Stem Cells Subgroup	10
Utilizing Indigenous Flora in East Africa for Breast Cancer Treatment: An Overview	10
Review of Therapies using TiO2 Nanomaterials for Increased Anticancer Capability	10
Aptamers in Osteosarcoma: New Paths for Diagnosis and Treatment	10
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis	10
Hsp27 Protects Triple-Negative Breast Cancer Cells against Carboplatin-Induced Cytotoxicity via the Maintenance of Late-Stage Autophagy	10
Exploring the CXCR4/CXCR7/CXCL12 Axis in Primary Desmoid Tumors	10
In vivo, In vitro, and In silico Studies of Umbelliferone and Irinotecan on MDA-MB-231 Breast Cancer Cell Line and Drosophila melanogaster Larvae	9
Design, Synthesis, Bioactivity, and Docking Studies of Isatin-Hydrazone Derivatives as Potential CDK-2 Inhibitors	9
GPR65 as a Laryngeal Cancer Risk Gene Identified through Single-Cell Transcriptomics, Mendelian Randomization Analysis, and Experimental Validation	9
Fish-Derived Antimicrobial Peptides (AMPs) as Anticancer Agents: A Mini-Review of In Vitro Evidence	9
Meet the Editorial Board Member	9
PEGylated Titanium Dioxide Nanoparticle-bound Doxorubicin and Paclitaxel Drugs Affect Prostate Cancer Cells and Alter the Expression of DUSP Family Genes	9
Recent Advancements in Organotin(IV) Complexes as Potent Cytotoxic Agents	9
Composition Analysis of Salsola grandis and Its Effects on Colon Cancer Cells	9
Enzalutamide Overcomes Dihydrotestosterone-Induced Chemoresistance in Triple- Negative Breast Cancer Cells via Apoptosis	9
PRR22: A Novel Prognostic Indicator and Therapeutic Target for Prostate Cancer	9
5-Fluorouracil-Impregnated PLGA Coated Gold Nanoparticles for Augmented Delivery to Lung Cancer: In Vitro Investigations	9
QSAR Study of Novel 1, 8-Naphthimide Derivatives Targeting Nuclear DNA	9
Gambogic Acid Lysinate-induced Cervical Cancer SiHa Cells Apoptosis in vitro and in vivo	9
Investigating the Activity of Indole-2-on Derivative Src Kinase Inhibitors Against Chronic Myeloid Leukemia Cells	9
Cucurbitacin E Glucoside as an Apoptosis Inducer in Melanoma Cancer Cells by Modulating AMPK/PGK1/PKM2 Pathway	9
Design of Novel Imidazopyrazine Derivative against Breast Cancer via Targeted NPY1R Antagonist	9
Carbon Nanotubes in Breast Cancer Treatment: An Insight into Properties, Functionalization, and Toxicity	8
Molecular Mechanisms of Sanguinarine in Cancer Prevention and Treatment	8
A Recent Advancement in Nanotechnology Approaches for the Treatment of Cervical Cancer	8
Role of Collagen Regulators in Cancer Treatment: A Comprehensive Review	8
Thiosemicarbazone-benzenesulfonamide Derivatives as Human Carbonic Anhydrases Inhibitors: Synthesis, Characterization, and In silico Studies	8
CD24 and Mutant p53: Emerging Therapeutic Targets in Prostate Cancer Progression	8
Anthracycline Drugs: An Update on Chemistry, Structure-Activity Relationship, Mechanism of Action, Cardiotoxicity, Physicochemical and Pharmacokinetic Properties	8
Optimized Rutin-incorporating PEGylated Nanoliposomes as a Model with Remarkable Selectivity Against PANC1 and MCF7 Cell Lines	8
Alterations of Krüppel-like Factor Signaling and Potential Targeted Therapy for Hepatocellular Carcinoma	8
Zerumbone Sensitizes the Anti-Cancer Efficacy of Cisplatin in Hepatocellular Carcinoma Cells	7
Dexamethasone Reduces Cell Adhesion and Migration of T47D Breast Cancer Cell Line	7
Observation on the Therapeutic Efficacy of Camrelizumab Combined with Chemotherapy in Non-small Cell Lung Cancer and the Cutaneous Immune-related Adverse Events: A Retrospective Study	7
Chitosan-Gold Nanogel Loaded with Doxorubicin: An Enhanced Delivery System for NSCLC Lung Cancer	7
Bacteriocins from Lactic Acid Bacteria Could Modulate the Wnt Pathway: A Possible Therapeutic Candidate for the Management of Colorectal Cancer- An In silico Study	7
Recent Advances and Therapeutic Journey of Schiff Base Complexes with Selected Metals (Pt, Pd, Ag, Au) as Potent Anticancer Agents: A Review	7
Decoding the Mechanism of Drugs of Heterocyclic Nature against Hepatocellular Carcinoma	7
Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells	7
ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification of Small-Molecule Inhibitors	7
Chloroform Fraction of Drymaria cordata Linn (CFDC) Suppresses Estradiol Benzoate- Induced Endometrial Hyperplasia	7
Combination of Second-Generation Proteasome Inhibitor Carfilzomib with Bortezomib in Four Different Breast Cancer Cell Lines	7
The Growth Inhibitory Effect of Resveratrol and Gallic Acid on Prostate Cancer Cell Lines through the Alteration of Oxidative Stress Balance: The Interplay between Nrf2, HO-1, and BACH1	7
Some Wild Mushrooms with High Antioxidant Capacity Exhibit Potent Anticancer Activity on Cancer Cells using the Apoptotic and Antimigration Cell Death Mechanisms	7
Synergistic Anti-tumorigenic Effects of Cabazitaxel and Usnic Acid Combination on Metastatic Castration-Resistant Prostate Cancer Cells	7
Interleukin-2 and Oncolytic Virotherapy: A New Perspective in Cancer Therapy	7
Bioactive Constituents and Potential Cytotoxic Activities of Green Microalgae: Desmodesmus spp. from a Jordanian Isolate	7
Anlotinib Inhibits Proliferation and Induces Apoptosis in B-cell Acute Lymphoblastic Leukemia by Targeting the BTK and AKT/mTOR Pathway	7
Antitumoral Potential of Artepillin C, a Compound Derived from Brazilian Propolis, against Breast Cancer Cell Lines	7
Antheraea proylei J. Sericin Induces Apoptosis in a Caspase-dependent Manner in A549 and HeLa Cells	7
Recent Advances in Natural Phytocompounds for the Chemotherapeutic Management of Head and Neck Squamous Cell Carcinoma from 2018–2024	7
A Review of Cryptotanshinone and its Nanoformulation in Cancer Therapy	7
Optimizing Coreopsis tinctoria Flower Extraction and Inhibiting CML Activity: Box-Behnken Design	7
Choosing the Right Protocol to Establish MCF-7 Tumor Xenograft in Nude Mice	7
Theranostic Potential of [177Lu]Lu-DOTA-Tocilizumab in Multiple Myeloma: A Preclinical Evaluation	7
The Role of Peptidyl Arginine Deiminase IV(PADI4) in Cancers	7
Frontiers and Approaches in Anticancer Drug Discovery: An Editorial Overview	7
Natural Compounds as Protease Inhibitors in Therapeutic Focus on Cancer Therapy	7

Corrigendum to: Alantolactone Inhibits Melanoma Cell Culture Viability and Migration and Promotes Apoptosis by Inhibiting Wnt/β-Catenin Signaling	7
Potentials of N-Acyl Hydrazones Against Colorectal Cancer: A Mini Review	6
Molecular Mechanisms of Chloroquine and Hydroxychloroquine Used in Cancer Therapy	6
Novel Heterocyclic Compounds Exhibit Potent Antileukemic Activity through Selective Induction of Apoptosis and HDAC8 Interaction in AML Cells	6
Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3- yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents	6
Decitabine Enhances Acute Myeloid Leukemia Cell Apoptosis through SH3BGRL Upregulation	6
WITHDRAWN: Metformin and 2-deoxy-D-glucose Synergistically Inhibit the Viability of Thyroid Papillary Carcinoma with BRAF Mutation by ROS-dependent PI3K/AKT Signaling Pathway	6
The Glucose-Regulated Protein78 (GRP78) in the Unfolded Protein Response (UPR) Pathway: A Potential Therapeutic Target for Breast Cancer	6
Targeting the LINC00324/miR-16-5p/SEPT2 Signaling Cascade is Effective to Reverse Malignant Phenotypes in Glioblastoma	6
The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance	6
Current Progress and Future Opportunities in Liquid Biopsy for Cancer Detection	6
Narrative Review Article A Comprehensive Review of the Anticancer Activity of Farnesiferol C and Umbelliferone	6
Cell Death Induced by the Combination of Ephedra sinica Extract and Radiation in HNSCC is Positively Related to BAX and p-MLKL Expression	6
Anticancer Compounds from Myxobacteria: Current Scenario and Future Perspectives	6
Advancements in Pyrazine Derivatives as Anticancer Agents: A Comprehensive Review (2010-2024)	6
Methyl (Z)-2-(Isothioureidomethyl)-2-pentenoate Hydrobromide Induces Cell Cycle Arrest and Disrupts Mitosis in a Melanoma Cell Line	6
Caffeic Acid Phenethyl Ester (CAPE) Inhibits Hepatocellular Carcinoma Growth and Angiogenesis via Vascular Endothelial Growth Factor Suppression: A Preclinical Evidence	6
Prognostic Value of Lactate Metabolism-Related Gene Signatures in Cancer Cells	6
Development of Antibody-Drug Conjugates: Future Perspective Towards Solid Tumor Treatment	6
A Review of Ferula Plant Compounds Against Breast Cancer: Which One Is Stronger for Breast Cancer Therapy?	6
New Approaches for the Synthesis of 2,3,5,6-Tetrahydrobenzo[d]thiazole Derivatives and their Anti-Proliferative, c-Met Enzymatic Activity and Tyrosine Kinases Inhibitions	6
A Molecular Approach of Caloric Restriction and Vitamins for Cancer Prevention	6
Isoproterenol-induced Upregulation of HPSE Accelerates Triple-negative Breast Cancer Cell Proliferation and Migration through Enhancing the Transcriptional Activity of HIF-1α	6
Naturally Occurring O-Heterocycles as Anticancer Agents	6
The Promising Role of PKM2 in the Diagnosis and Prognosis of Ovarian Cancer	6
Screening and in vitro Biological Evaluation of Novel Multiple Tyrosine Kinases Inhibitors as Promising Anticancer Agents	6
The Cytotoxic and Anti-tumor Potential of Methanolic Extracts of Indian Marine Isolates in HCT116 Colorectal Cancer Cells	6
Osimertinib Induces the Opposite Effect of Proliferation and Migration in the Drug Resistance of EGFR-T790M Non-small Cell Lung Cancer Cells	6
Genetic and Molecular Determinants of Immunotherapy Response in Recurrent Ovarian Cancer	6
Meet the Editorial Board Member	6
Advancements in Small Molecule PROTACs Containing Indole/Spiro-fused Oxindole Scaffolds: An Emerging Degrader Targeting Cancers	6
Medicinal Chemistry of Natural Anti-Skin Cancer Agents: An Evidence-Based Literature Review	6
State of the Art of IDH Inhibitors: Emerging Questions and Perspectives	6
A Systematic Review and Meta-analysis of the Relationship between Statin Intake and Esophageal Cancer	6
Investigation of the Apoptosis Inducing and β-catenin Silencing by Tetradentate Schiff Base Zinc(II) Complex on the T-47D Breast Cancer Cells	6
In silico-driven identification of Pranlukast as a Stabilizer of PD-L1 Homodimers	6
Meet the Editorial Board Member	5
Drug Repositioning for Ovarian Cancer Treatment: An Update	5
CD98 Light Chain LAT1 Tracers in PET-CT Diagnosis of Cancer Patients	5
Berbamine Inhibits the Biological Activities of Prostate Cancer Cells by Modulating the ROS/NF-κB Axis	5
Targeting TGF-βR1 Signaling Pathway in Pancreatic Cancer: A Potential Approach with Synthetic Flavanols	5
A Path to the Formation Mechanism of Propolis Nanoparticles, their Cytotoxicity on 3T3 Fibroblasts, Metastatic Murine B16F10 Cells, and their In vivo Irritability in Animals	5
A Contemporary Review on the Critical Role of Nonsteroidal Anti-inflammatory Agents in Colorectal Cancer Therapy	5
Apoptosis-Mediated Anticancer Activity of Zinc Oxide Nanoparticles Derived and Characterized from Halophila beccarii	5
Qualitative Analysis and Cytotoxic Activity of Ethanolic Extract of Piper betle Linn. Leaves: Induction of Apoptosis, Cell Cycle Arrest, and Caspase-3/7 Activation in HER2+ AU565 Breast Cancer Cell Li	5
Metformin-Induced Ferroptosis as a Novel Therapeutic Strategy for Cancer	5
A Needle in a Haystack: The Precision of Liquid Biopsy in Finding Bone Tumors	5
Investigation of the Immunomodulatory Effect of Quinoline Derivatives with Antitumor Activity	5
Immunologic Mechanisms of BCc1 Nanomedicine Synthesized by Nanochelating Technology in Breast Tumor-bearing Mice: Immunomodulation and Tumor Suppression	5
Imidazole and Biphenyl Derivatives as Anti-cancer Agents for Glioma Therapeutics: Computational Drug Repurposing Strategy	5
Synthesis of Chromene-linked Bis-indole Derivatives as Selective Tumor-associated Carbonic Anhydrase IX Inhibitors	5
Konjac Glucomannan, in Combination with Cisplatin, Suppresses Lymphoma Malignant Progression by Inducing Ferroptosis	5
p-Coumaric Acid Inhibits Osteosarcoma Growth by Inhibiting PI3K/Akt Signaling Pathway	5
Uses of Cyclohexan-1,3-diones to Synthesis Xanthenes Derivatives with Anti-proliferative Activity Against Cancer Cell Lines and their Inhibitions Toward Tyrosine Kinases	5
Targeting Ferroptosis: Small-molecule Inducers as Novel Anticancer Agents	5
Recent Advances in the Chemistry and Biology of Bakuchiol and its Derivatives: An Updated Review	5
JHD205, A Novel Abemaciclib Derivative, Exerts Antitumor Effects on Breast Cancer by CDK4/6	5
Secondary Malignancies of Chimeric Antigen Receptor T-cell Therapy: A Multidimensional Analysis of Mechanisms, Risk Factors, and Treatment Strategies	5
Preparation of a Novel Multifunctional Cationic Liposome Drug-carrying System and its Functional Study on Lung Cancer	5
Decoding the Anticancer Potential of Natural N-Heterocycles: Molecular Frameworks, Bioactivity, and Mechanistic Advances	5
Glycyrrhetinic Acid in Cancer Therapy: Mechanistic Insights, Therapeutic Potential, and Future Directions	5
Secretory Phospholipase A2 (sPLA2) Isozymes as Potential Targets in Tobacco Condensate- induced Colon Damage	5
Sulphur Containing Heterocyclic Compounds as Anticancer Agents	5
Rhizopogon luteolus and Ganoderma adspersum Extracts Inhibit Invasion through the Crosstalk between Anti-oxidant Activity and Apoptosis Induced by pAKT/Rb	5
Pioneering the Battle Against Breast Cancer: The Promise of New Bcl-2 Family	5
WITHDRAWN: The Anticancer Mechanism of Terpenoid-based Drug Candidates: Focus on Tumor Microenvironment	5
Anti-tumoral Immunity and Chemo-preventive Effectiveness of Herbal Extracts of Curcumin, Ginger, Clove and Amygdaline in Ehrlich Ascites Carcinoma-Challenging Mice	5
Investigating the Anti-tumor and Apoptosis-inducing Effects of Coumarin Derivatives as Potent 15-Lipoxygenase Inhibitors on PC-3 Prostate Cancer Cells	5
Targeting Telomere Shelterin Protein TPP1 with Elbasvir: Induction of Autophagy and Suppression of Esophageal Cancer Tumorigenesis	5
Drug Targeting and Therapeutic Management of Chronic Myeloid Leukemia: Conventional and Nanotherapeutic Drug Options	5
Amide Functionalized Novel Pyrrolo-pyrimidine Derivative as Anticancer Agents: Synthesis, Characterization and Molecular Docking Studies	5
Galbanic Acid Improves Accumulation and Toxicity of Arsenic Trioxide in MT-2 Cells	5
Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells -An In vitroandIn silicoStudy	5
Diosgenin Glucoside Inhibits the Progression of Osteosarcoma MG-63 by Regulating the PI3K/AKT/mTOR Pathway	5
Combating Sorafenib Resistance in Hepatocellular Carcinoma: Unlocking Potential with Combination Therapies and Structure-Activity Relationship Studies	5
Antitumor Effects of Turmeric on OVCAR-3 Ovarian Cancer Cell Lines	5
Camphor and Menthol as Anticancer Agents: Synthesis, Structure-Activity Relationship and Interaction with Cancer Cell Lines	5
Caracasine, An ent-kaurane Diterpene with Proapoptotic and Pro-differentiator Activity in Human Leukaemia Cell Lines	5
An Active Compound from the Pyrazine Family Induces Apoptosis by Targeting the Bax/Bcl2 and Survivin Expression in Chronic Myeloid Leukemia K562 Cells	5
Antiproliferative Effects of Artabotrys odoratissimus Fruit Extract and its Bioactive Fraction through Upregulation of p53/γH2AX Signals and G2/M Phase Arrest in MIA PaCa-2 Cells	5
Insight into the Tubulin-Targeted Anticancer Potential of Noscapine and its Structural Analogs	4
Germacrone, A Novel and Safe Anticancer Agent from Genus Curcuma: A Review of its Mechanism	4
Synthesis of New Chromen-5-one Derivatives from Dimedone and their Antiproliferative Evaluations against Selected Cancer Cell Lines Together with Hepatocellular Carcinoma and Cervical Carcinoma	4
Celastrus orbiculatus Extract Inhibits the Epithelial-Mesenchymal Transition Process by Transforming Growth Factor-β Signaling Pathway in Gastric Cancer	4
Melittin, A Potential Game-changer in the Fight Against Breast Cancer: A Systematic Review	4
Design, Synthesis, and Antiproliferative Activity of Quinazolin-4-One/Chalcone Hybrids via the EGFR Inhibition Pathway	4
Cervical Cancer Therapeutics: An In-depth Significance of Herbal and Chemical Approaches of Nanoparticles	4
Arctigenin Suppresses the Proliferation and Metastasis, and Induces Apoptosis and Cycle Arrest of Osteosarcoma Cells by inhibiting HMOX1 Expression	4
Meet the Co-Editor	4
Therapeutic Effects of Crocin Nanoparticles Alone or in Combination with Doxorubicin against Hepatocellular Carcinoma In vitro	4
The Kinesin Eg5 Inhibitor K858 Enhances Radiosensitivity in Esophageal Squamous Cell Carcinoma and Affects the Expression of Epithelial-mesenchymal Transition Related Markers: In vitro and In vivo Stu	4
Molecular Docking and In Vitro Anticancer Screening of Synthesized Arylthiazole linked 2H-indol-2-one Derivatives as VEGFR-2 Kinase Inhibitors	4
Venetoclax Synergizes Sunitinib in Renal Cell Carcincoma through Inhibition of Bcl-2	4
A Systematic Review and Meta-analysis on the Safety and Efficacy of CAR T Cell Therapy Targeting GPRC5D in Patients with Multiple Myeloma: A New Insight in Cancer Immunotherapy	4
Novel 1,4-Dihydropyrido[2,3-B]Pyrazine-2,3-Dione Derivatives for Treating Cancer and Other Disorders Associated with KRAS Activity	4