Anti-Cancer Agents in Medicinal Chemistry

Papers
(The median citation count of Anti-Cancer Agents in Medicinal Chemistry is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Meet the Editorial Board Member243
Synthesis and in vitro Anti-proliferative Activities on LNCaP, LS180 and MKN45 of Novel 20(R)-Panaxadiol Derivatives129
Preface69
Recent Achievements about Targeted Alpha Therapy-Based Targeting Vectors and Chelating Agents63
Timosaponin A-III Induces ROS-mediated Apoptosis and Triggers Protective Autophagy via the AMPK/mTOR Pathway in Prostate Cancer54
Design, Synthesis and Biological Evaluation of New 4-(4-(Methylsulfonyl) Phenyl)-6-Phenylpyrimidin-2-Amine Derivatives as Selective Cyclooxygenase (COX-2) Inhibitors48
Design, Synthesis, Antimicrobial and Antitumor Activities of Benzo[f]chromene Derivatives: DFT and Molecular Docking43
Innovative Nanocarriers: Magnetosomes in the Fight against Cancer41
PREFACE40
Retracted: Anti-proliferative, Morphological and Molecular Docking Studies of New Thiophene Derivatives and their Strategy in Ionic Liquids Immobilized Reactions39
CYP1B1: A Promising Target in Cancer Drug Discovery35
Unveiling the Potential of S4 on Non-small Cell Lung Cancer Cells: Impact on Proliferation, Apoptosis, Senescence, and Metabolome Profile32
Diterpenoid Tanshinone Attenuates the Metastasis of Non-small-cell Lung Cancer (NSCLC) Cells by Inhibiting the Cavin-1-mediated ERK/Smad2 Signaling Pathway32
The Importance of Structural Water in HDAC8 for Correct Binding Pose Applied for Drug Design of Anticancer Molecules32
Design, Synthesis, In vitro and In vivo Evaluation of New Imidazo[1,2-a]pyridine Derivatives as Cyclooxygenase-2 Inhibitors30
The Effect of Iron Oxide Nanoparticles of Acalypha wilkesiana Ethyl Acetate Extract on Ehrlich Ascites Carcinoma Cells29
Berberine Hydrochloride Inhibits the Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells by Regulating Amino Acid Metabolism28
Celastrol Inhibits the Proliferation and Decreases Drug Resistance of Cisplatin- Resistant Gastric Cancer SGC7901/DDP Cells27
Processed Products of Aconitum soongaricum Stapf. Inhibit the Growth of Ovarian Cancer Cells In vivo via Regulating the PI3K/AKT Signal Pathway26
Construction of Biomimetic-Responsive Nanocarriers and their Applications in Tumor Targeting26
Effects of Arctigenin in Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma 5-8F Cells26
Network Pharmacology-Based and Molecular Docking Analysis of Resveratrol’s Pharmacological Effects on Type I Endometrial Cancer26
Natural Compounds as Promising Adjuvants in Cancer Therapy; Sensitizer of Cancer Cells, and Protector of Healthy Cells25
Current Insight into the Therapeutic Potential of Phytocompounds and their Nanoparticle-Based Systems for Effective Management of Lung Cancer25
Recent Advancement in the Inhibition of Triple-negative Breast Cancer by N-heterocycles25
The Combination of Chrysin and Cisplatin Induces Apoptosis in HepG2 through Down-regulation of cFLIP and Activity of Caspase24
MDM2-mediated Inhibitory Effect of Arsenic Trioxide on Small Cell Lung Cancer Cell Line by Degrading Mutant p5324
High Diagnostic and Prognostic Value of miRNAs Compared with the Carcinoembryonic Antigen As A Traditional Tumor Marker24
Rapid Arc-SBRT: Non-Invasive Immune Adjuvant for Advanced Stage Non-Small Cell Lung Carcinoma24
dHG-5 Exhibits Dual Efficacy of Anti-Metastatic and Anti-hypercoagulability inMice by Inhibiting Heparanase and Intrinsic Coagulation Pathway23
Anti-Tumor and Anti-Metastasis Effects of Berbamine-Loaded Lipid Nanoparticles on Pancreatic Cancer22
Enhanced Apoptosis in Pancreatic Cancer Cells through Thymoquinone-rich Nigella sativa L. Methanol Extract: Targeting NRF2/HO-1 and TNF-α Pathways22
Determination of Pralsetinib in Human Plasma and Cerebrospinal Fluid for Therapeutic Drug Monitoring by Ultra-performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)21
Treatment of Triple Negative Cell Lines with Olaparib to Block DNA Repair21
Apatinib Inhibits Stem Properties and Malignant Biological Behaviors of Breast Cancer Stem Cells by Blocking Wnt/β-catenin Signal Pathway through Downregulating LncRNA ROR21
The Effect of Hydroquinidine on Proliferation and Apoptosis of TMZ-sensitive and -resistant GBM Cells21
HSP Inhibitor Sensitize Resistant MCF-7 Cells to Doxorubicin through SuppressingHSP90AB4P Pseudogene and HSPB1 Expression21
Design, Synthesis, and Apoptosis-Promoting Effect Evaluation of Chalcone Derivatives Containing Aminoguanidine Units20
PHD-BAH Domain in ASH1L Could Recognize H3K4 Methylation and Regulate the Malignant Behavior of Cholangiocarcinoma20
Cepharanthine Regulates Autophagy via Activating the p38 Signaling Pathway in Lung Adenocarcinoma Cells20
Synthesis of New Pyrazole Hybrids as Potential Anticancer Agents with Xanthine Oxidase Inhibitory Activity19
Apoptosis-inducing Metabolite from Marine Mangrove Actinobacteria VITGAP17319
QSAR Research of Novel Tetrandrine Derivatives against Human Hepatocellular Carcinoma19
Different Methods for Cell Viability and Proliferation Assay: Essential Tools in Pharmaceutical Studies18
Revealing the Role of the Arg and Lys in Shifting Paradigm from BTK Selective Inhibition to the BTK/HCK Dual Inhibition - Delving into the Inhibitory Activity of KIN-8194 against BTK, and HCK in the T18
Melatonin Enhances Anti-tumoral Effects of Menadione on Colon Cancer Cells18
Rational Design of Anti-Angiogenic Peptides to Inhibit VEGF/VEGFR2 Interactions for Cancer Therapeutics18
Identification of Natural Compounds to Inhibit Sonic Hedgehog Pathway in Oral Cancer18
Design, Synthesis, Anticancer Evaluation, and Molecular Docking Studies of Novel Benzoxazole Linked 1,3,4-Oxadiazoles18
1,3-Diaryl Triazenes Incorporating Disulfonamides Show Both Antiproliferative Activity and Effective Inhibition of Tumor-associated Carbonic Anhydrases IX and XII17
Polyphenols as the Potential Disease-modifying Therapy in Cancer16
3-Bromopyruvate Inhibits the Growth and Glucose Metabolism of TNBC Xenografts in Nude Mice by Targeting c-Myc16
WITHDRAWN: Monochasma savatieri Inhibits the Migration of the Breast Cancer Cell Line MDA-MB-23116
ALK and ERBB2 Protein Inhibition is Involved in the Prevention of Lung Cancer Development by Vincamine16
Molecular Activities and Mechanisms of Action of Substances and Molecules from Medicinal Plants from Sub-Saharan Africa on Prostate and Cervical Cancer Cells16
ADME Prediction, Structure-activity Relationship of Boswellic Acid Scaffold for the Aspect of Anticancer & Anti-inflammatory Potency16
Antidepressant Sertraline Hydrochloride Inhibits the Growth of HER2+ AU565 Breast Cancer Cell Line through Induction of Apoptosis and Cell Cycle Arrest16
Doramectin Induces Apoptosis in B16 Melanoma Cells16
Heterocyclic Compounds: Importance in Anticancer Drug Discovery15
Patterns of Cell Death Induced by Thiohydantoins in Human MCF-7 Breast Cancer Cells15
Quercetin-based Nanoformulation: A Potential Approach for Cancer Treatment15
Molecular Targets of Plant-based Alkaloids and Polyphenolics in Liver and Breast Cancer- An Insight into Anticancer Drug Development15
Unveiling the Therapeutic Potential of Trigonelline: A Promising Approach in Cancer Prevention and Treatment15
Computational Exploration of Anti-Cancer Potential of GUAIANE Dimers from Xylopia vielana by Targeting B-Raf Kinase Using Chemo-Informatics, Molecular Docking, and MD Simulation Studies15
Design and Development of Triazole Derivatives as Prospective Anticancer Agents: A Review14
Karanjin, A Promising Bioactive Compound Possessing Anti-cancer Activity against Experimental Model of Non-small Cell Lung Cancer Cells14
Significance of Chalcone Synthons as Lead Molecules in Anticancer Drug Discovery14
Synthesis and Biological Studies of Aurones Derivatives for its Anticancer Potential14
Targeting Glutamine Metabolism through Glutaminase Inhibition Suppresses Cell Proliferation and Progression in Nasopharyngeal Carcinoma14
Meet the Section Editor14
Primary Pulmonary Lymphoepithelioma-like Carcinoma: A Case Report Utilizing Camrelizumab and Anlotinib for Prolonged Survival14
Luteolin Enhances Anticancer Effects of PX-478 during Hypoxic Response in Metastatic Breast Cancer Cells14
Natural Products and Gastric Cancer: Cellular Mechanisms and Effects to Change Cancer Progression14
Overexpression of Bromodomain and Extraterminal Domain is Associated with Progression, Metastasis and Unfavorable Outcomes: Highlighting Prognostic and Therapeutic Value of the BET Protein Family in G14
MDR Inhibitors for Anticancer Therapy14
Structural Aspects of mTOR Inhibitors: Search for Potential Compounds14
An Outlook of the Structure Activity Relationship (SAR) of Naphthalimide Derivatives as Anticancer Agents14
Newly Synthesized Benzimidazoles Inhibit Vascular Endothelial Growth Factor and Matrix Metalloproteinase-2 and -9 Levels in Prostate Cancer Cells14
Molecular Mechanisms Responsible for In Vitro Cytotoxic Attributes of Conyza bonariensis Extract against Lymphoblastic Leukaemia Jurkat Cells13
Exploring Phytochemicals from Himalayan Medicinal Plants as Novel Therapeutic Agents13
Effects of Melatonin and Doxorubicin on Primary Tumor And Metastasis in Breast Cancer Model13
Precision Therapy for Prostate Cancer: Advancements in Polymeric Nanocarrier Systems13
Advances in VEGFR Inhibitors: A Comprehensive Review of Novel Anticancer Agents13
Tisotumab Vedotin: The First FDA-Approved Antibody-Drug Conjugate for Cervical Cancer13
Matrix Metalloproteinases in Oral Cancer Pathogenesis and their Use in Therapy13
Bakuchiol: A Potential Anticancer Compound from Psoralea corylifolia Linn13
Gastrodin Attenuates Colitis and Prevents Tumorigenesis in Mice by Interrupting TLR4/MD2/NF-κB Signaling Transduction13
HLTF Promotes the Proliferation of Osteosarcoma Cells and Cisplatin Resistance13
Celastrol Inhibits the Proliferation and Induces Apoptosis of Colorectal Cancer Cells via Downregulating NF-κB/COX-2 Signaling Pathways13
Chemical Characterization, In-silico Evaluation, and Molecular Docking Analysis of Antiproliferative Compounds Isolated from the Bark of Anthocephalus cadamba Miq.13
Probiotics for the Chemoprotective Role against the Toxic Effect of Cancer Chemotherapy13
Maternal Embryonic Leucine Zipper Kinase (MELK) as a Promising Therapeutic Target in Triple Negative Breast Cancer13
Agrimonolide Inhibits the Malignant Progression of Non-small Cell Lung Cancer and Induces Ferroptosis through the mTOR Signaling Pathway13
Meet the Associate Editorial Board Member12
Eco-friendly Synthesis and Characterization of Silver Nanoparticles using Juglans regia Extract and their Anti-Trichomonas vaginalis, Anticancer, and Antimicrobial Effects12
Baicalin Inhibits Lung Cancer Cell Proliferation and Migration via ALOX12-Mediated Ferroptosis12
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription12
Cytotoxic Evaluation and Molecular Docking Studies of Aminopyridine Derivatives as Potential Anticancer Agents12
Efficacy of Neoadjuvant Therapy in Improving Long-Term Survival of Patients with Resectable Rectal Cancer: A Meta-Analysis12
Novel Synthetic Indazoles Abrogate Angiogenesis in Erlich Ascites Tumor Bearing Mice12
S16020 Pyridocarbazole Derivatives Display High Activity to Lung Cancer Cells12
Meet the Editorial Board Member12
Evaluation of Benzamide-Chalcone Derivatives as EGFR/CDK2 Inhibitor: Synthesis, In-Vitro Inhibition, and Molecular Modeling Studies12
Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from Nigella sativa L.12
Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis12
A Green Synthesis of Au-Ag Alloy Nanoparticles using Polydopamine Chemistry: Evaluation of their Anticancer Potency Towards Both MCF-7 Cells and their Cancer Stem Cells Subgroup12
Innovative Therapies for Oncogenic KRAS Mutations: Precision Strategies withPROTACs in Cancer Treatment11
Synergism Effect of Dendrobine on Cisplatin in Treatment of H1299 by Modulating the Balance of Treg/Th1711
Lupiwighteone as an Antitumor Agent Reverses Multidrug Resistance in K562/ADR Cells by Regulating Cellular Prion Protein-Oct4 Axis11
Utilizing Indigenous Flora in East Africa for Breast Cancer Treatment: An Overview11
Corrigendum to: “An Overview of Conventional Drugs and Nanotherapeutic Options for the Treatment and Management of Pediatric Acute Lymphoblastic Leukemia”11
Unveiling the Vital Role of ACTA2-AS1 in Human Cancers: Molecular Mechanisms and Clinical Applications11
Antibody Drug Conjugates (ADCs): Shaping the Future of Precision Oncology11
Curcumin and its Analogues in Oral Squamous Cell Carcinoma: State-of-the-art and Therapeutic Potential11
Royal Jelly's Strong Selective Cytotoxicity Against Lung Malignant Cells and Macromolecular Alterations in Cells Observed by FTIR Spectroscopy11
Retraction Notice to "The Natural Flavonoid Naringenin Inhibits the Cell Growth of Wilms Tumor in Children by Suppressing TLR4/NF-κB Signaling"11
Liposomal Drug Delivery and Its Potential Impact on Cancer Research11
Review of Therapies using TiO2 Nanomaterials for Increased Anticancer Capability11
New Frontiers in the Discovery and Development of PROTACs11
GPR65 as a Laryngeal Cancer Risk Gene Identified through Single-Cell Transcriptomics, Mendelian Randomization Analysis, and Experimental Validation10
Zerumbone Sensitizes the Anti-Cancer Efficacy of Cisplatin in Hepatocellular Carcinoma Cells10
5-Fluorouracil-Impregnated PLGA Coated Gold Nanoparticles for Augmented Delivery to Lung Cancer: In Vitro Investigations10
Trailing TRAIL Resistance in Human Breast Adenocarcinoma Cells with Trichostatin A and Zebularine10
Exploring the CXCR4/CXCR7/CXCL12 Axis in Primary Desmoid Tumors10
Enzalutamide Overcomes Dihydrotestosterone-Induced Chemoresistance in Triple- Negative Breast Cancer Cells via Apoptosis10
Thiosemicarbazone-benzenesulfonamide Derivatives as Human Carbonic Anhydrases Inhibitors: Synthesis, Characterization, and In silico Studies10
Alterations of Krüppel-like Factor Signaling and Potential Targeted Therapy for Hepatocellular Carcinoma10
lncRNAs as Hallmarks for Individualized Treatment of Gastric Cancer10
QSAR Study of Novel 1, 8-Naphthimide Derivatives Targeting Nuclear DNA10
PEGylated Titanium Dioxide Nanoparticle-bound Doxorubicin and Paclitaxel Drugs Affect Prostate Cancer Cells and Alter the Expression of DUSP Family Genes10
Composition Analysis of Salsola grandis and Its Effects on Colon Cancer Cells10
PRR22: A Novel Prognostic Indicator and Therapeutic Target for Prostate Cancer10
In vivo, In vitro, and In silico Studies of Umbelliferone and Irinotecan on MDA-MB-231 Breast Cancer Cell Line and Drosophila melanogaster Larvae10
Design, Synthesis and Biological Evaluation of Novel Triazolothiadiazoles Derived from NSAIDs as Anticancer Agents10
Meet the Editorial Board Member10
Design of Novel Imidazopyrazine Derivative against Breast Cancer via Targeted NPY1R Antagonist10
Optimized Rutin-incorporating PEGylated Nanoliposomes as a Model with Remarkable Selectivity Against PANC1 and MCF7 Cell Lines10
Investigating the Activity of Indole-2-on Derivative Src Kinase Inhibitors Against Chronic Myeloid Leukemia Cells10
A Recent Advancement in Nanotechnology Approaches for the Treatment of Cervical Cancer9
Role of Collagen Regulators in Cancer Treatment: A Comprehensive Review9
Carbon Nanotubes in Breast Cancer Treatment: An Insight into Properties, Functionalization, and Toxicity9
Meet the Editorial Board Member9
Bacteriocins from Lactic Acid Bacteria Could Modulate the Wnt Pathway: A Possible Therapeutic Candidate for the Management of Colorectal Cancer- An In silico Study9
Anlotinib Inhibits Proliferation and Induces Apoptosis in B-cell Acute Lymphoblastic Leukemia by Targeting the BTK and AKT/mTOR Pathway9
Cucurbitacin E Glucoside as an Apoptosis Inducer in Melanoma Cancer Cells by Modulating AMPK/PGK1/PKM2 Pathway9
The Role of Peptidyl Arginine Deiminase IV(PADI4) in Cancers9
Recent Advances and Therapeutic Journey of Schiff Base Complexes with Selected Metals (Pt, Pd, Ag, Au) as Potent Anticancer Agents: A Review9
Meet the Editorial Board Member9
Decoding the Mechanism of Drugs of Heterocyclic Nature against Hepatocellular Carcinoma9
Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry- Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells9
Smoking is Associated with Lung Adenocarcinoma and Lung Squamous Cell Carcinoma Progression through Inducing Distinguishing lncRNA Alterations in Different Genders9
Recent Advancements in Organotin(IV) Complexes as Potent Cytotoxic Agents9
Gambogic Acid Lysinate-induced Cervical Cancer SiHa Cells Apoptosis in vitro and in vivo9
Molecular Mechanisms of Sanguinarine in Cancer Prevention and Treatment9
Frontiers and Approaches in Anticancer Drug Discovery: An Editorial Overview9
Synergistic Anti-tumorigenic Effects of Cabazitaxel and Usnic Acid Combination on Metastatic Castration-Resistant Prostate Cancer Cells9
Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells8
Protective Effect of Nerium oleander Distillate and Tarantula cubensis Alcoholic Extract on Cancer Biomarkers in Colon and Liver Tissues of Rats with Experimental Colon Cancer8
ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification of Small-Molecule Inhibitors8
Some Wild Mushrooms with High Antioxidant Capacity Exhibit Potent Anticancer Activity on Cancer Cells using the Apoptotic and Antimigration Cell Death Mechanisms8
Combination of Second-Generation Proteasome Inhibitor Carfilzomib with Bortezomib in Four Different Breast Cancer Cell Lines8
Cytotoxic Impact of N-Oleoylethanolamine on Bone Cancer Cells8
Quinoline-3-Carboxylic Acids “DNA Minor Groove-Binding Agent”8
Interleukin-2 and Oncolytic Virotherapy: A New Perspective in Cancer Therapy8
A Review of Cryptotanshinone and its Nanoformulation in Cancer Therapy8
Observation on the Therapeutic Efficacy of Camrelizumab Combined with Chemotherapy in Non-small Cell Lung Cancer and the Cutaneous Immune-related Adverse Events: A Retrospective Study8
Antheraea proylei J. Sericin Induces Apoptosis in a Caspase-dependent Manner in A549 and HeLa Cells8
Chloroform Fraction of Drymaria cordata Linn (CFDC) Suppresses Estradiol Benzoate- Induced Endometrial Hyperplasia8
Natural Compounds as Protease Inhibitors in Therapeutic Focus on Cancer Therapy8
The Growth Inhibitory Effect of Resveratrol and Gallic Acid on Prostate Cancer Cell Lines through the Alteration of Oxidative Stress Balance: The Interplay between Nrf2, HO-1, and BACH1 8
SphK1 Promotes Cancer Progression through Activating JAK/STAT Pathway and Up-Regulating S1PR1 Expression in Colon Cancer Cells8
Optimizing Coreopsis tinctoria Flower Extraction and Inhibiting CML Activity: Box-Behnken Design8
Effects of Sambucus ebulus Extract on Cell Proliferation and Viability of Triple- Negative Breast Cancer: An In Vitro and In Vivo Study8
Corrigendum to: Alantolactone Inhibits Melanoma Cell Culture Viability and Migration and Promotes Apoptosis by Inhibiting Wnt/β-Catenin Signaling8
Anti-oxidant and Anticancerous Effect of Fomitopsis officinalis (Vill. ex Fr. Bond. et Sing) Mushroom on Hepatocellular Carcinoma Cells In Vitro through NF-kB Pathway8
Choosing the Right Protocol to Establish MCF-7 Tumor Xenograft in Nude Mice8
Dexamethasone Reduces Cell Adhesion and Migration of T47D Breast Cancer Cell Line8
Antitumoral Potential of Artepillin C, a Compound Derived from Brazilian Propolis, against Breast Cancer Cell Lines8
Nilotinib, A Tyrosine Kinase Inhibitor, Suppresses the Cell Growth and Triggers Autophagy in Papillary Thyroid Cancer8
The Glucose-Regulated Protein78 (GRP78) in the Unfolded Protein Response (UPR) Pathway: A Potential Therapeutic Target for Breast Cancer7
Prospects of Delivering Natural Compounds by Polymer-Drug Conjugates in Cancer Therapeutics7
A Systematic Review and Meta-analysis of the Relationship between Statin Intake and Esophageal Cancer7
Investigation of the Apoptosis Inducing and β-catenin Silencing by Tetradentate Schiff Base Zinc(II) Complex on the T-47D Breast Cancer Cells7
Narrative Review Article A Comprehensive Review of the Anticancer Activity of Farnesiferol C and Umbelliferone7
The Photodynamic Anti-Tumor Effects of New PPa-CDs Conjugate with pH Sensitivity and Improved Biocompatibility7
Development of Antibody-Drug Conjugates: Future Perspective Towards Solid Tumor Treatment7
Meet the Editorial Board Member7
Potentials of N-Acyl Hydrazones Against Colorectal Cancer: A Mini Review7
Naturally Occurring O-Heterocycles as Anticancer Agents7
Anti-Cancer and Anti-Inflammatory Potential of Furanocoumarins from Ammi majus L.7
The Promising Role of PKM2 in the Diagnosis and Prognosis of Ovarian Cancer7
A Molecular Approach of Caloric Restriction and Vitamins for Cancer Prevention7
Prospects of Treating Prostate Cancer through Apalutamide: A Mini-Review7
Sulphur Containing Heterocyclic Compounds as Anticancer Agents7
Screening and in vitro Biological Evaluation of Novel Multiple Tyrosine Kinases Inhibitors as Promising Anticancer Agents7
Molecular Mechanisms of Chloroquine and Hydroxychloroquine Used in Cancer Therapy7
Decitabine Enhances Acute Myeloid Leukemia Cell Apoptosis through SH3BGRL Upregulation7
Cell Death Induced by the Combination of Ephedra sinica Extract and Radiation in HNSCC is Positively Related to BAX and p-MLKL Expression7
Imidazolidine Derivatives in Cancer Research: What is known?7
Anticancer Compounds from Myxobacteria: Current Scenario and Future Perspectives7
Isoproterenol-induced Upregulation of HPSE Accelerates Triple-negative Breast Cancer Cell Proliferation and Migration through Enhancing the Transcriptional Activity of HIF-1α7
In silico-driven identification of Pranlukast as a Stabilizer of PD-L1 Homodimers7
Advancements in Small Molecule PROTACs Containing Indole/Spiro-fused Oxindole Scaffolds: An Emerging Degrader Targeting Cancers7
Preparation of a Novel Multifunctional Cationic Liposome Drug-carrying System and its Functional Study on Lung Cancer7
New Approaches for the Synthesis of 2,3,5,6-Tetrahydrobenzo[d]thiazole Derivatives and their Anti-Proliferative, c-Met Enzymatic Activity and Tyrosine Kinases Inhibitions7
Advancements in Pyrazine Derivatives as Anticancer Agents: A Comprehensive Review (2010-2024)7
ConA-Coated Liposomes as a System to Delivery β-Lapachone to Breast Cancer Cells6
Immunologic Mechanisms of BCc1 Nanomedicine Synthesized by Nanochelating Technology in Breast Tumor-bearing Mice: Immunomodulation and Tumor Suppression6
Precision Oncology, Signaling, and Anticancer Agents in Cancer Therapeutics6
Targeting the LINC00324/miR-16-5p/SEPT2 Signaling Cascade is Effective to Reverse Malignant Phenotypes in Glioblastoma6
Diosgenin Glucoside Inhibits the Progression of Osteosarcoma MG-63 by Regulating the PI3K/AKT/mTOR Pathway6
Konjac Glucomannan, in Combination with Cisplatin, Suppresses Lymphoma Malignant Progression by Inducing Ferroptosis6
Amide Functionalized Novel Pyrrolo-pyrimidine Derivative as Anticancer Agents: Synthesis, Characterization and Molecular Docking Studies6
Novel Suberoylanilide Hydroxamic Acid Analogs Inhibit Angiogenesis and Induce Apoptosis in Breast Cancer Cells6
Targeting TGF-βR1 Signaling Pathway in Pancreatic Cancer: A Potential Approach with Synthetic Flavanols6
The Cytotoxic and Anti-tumor Potential of Methanolic Extracts of Indian Marine Isolates in HCT116 Colorectal Cancer Cells6
CD98 Light Chain LAT1 Tracers in PET-CT Diagnosis of Cancer Patients6
Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells6
Berbamine Inhibits the Biological Activities of Prostate Cancer Cells by Modulating the ROS/NF-κB Axis6
Methyl (Z)-2-(Isothioureidomethyl)-2-pentenoate Hydrobromide Induces Cell Cycle Arrest and Disrupts Mitosis in a Melanoma Cell Line6
A Contemporary Review on the Critical Role of Nonsteroidal Anti-inflammatory Agents in Colorectal Cancer Therapy6
Camphor and Menthol as Anticancer Agents: Synthesis, Structure-Activity Relationship and Interaction with Cancer Cell Lines6
A Path to the Formation Mechanism of Propolis Nanoparticles, their Cytotoxicity on 3T3 Fibroblasts, Metastatic Murine B16F10 Cells, and their In vivo Irritability in Animals6
Apoptosis-Mediated Anticancer Activity of Zinc Oxide Nanoparticles Derived and Characterized from Halophila beccarii6
Meet the Editorial Board Member6
A Pan-cancer Analysis Reveals the Abnormal Expression and Drug Sensitivity of CSF16
Uses of Cyclohexan-1,3-diones to Synthesis Xanthenes Derivatives with Anti-proliferative Activity Against Cancer Cell Lines and their Inhibitions Toward Tyrosine Kinases6
Antimetastatic Potential of Quercetin Analogues with Improved Pharmacokinetic Profile: A Pharmacoinformatic Preliminary Study6
Targeting Ferroptosis: Small-molecule Inducers as Novel Anticancer Agents6
Secondary Malignancies of Chimeric Antigen Receptor T-cell Therapy: A Multidimensional Analysis of Mechanisms, Risk Factors, and Treatment Strategies6
Osimertinib Induces the Opposite Effect of Proliferation and Migration in the Drug Resistance of EGFR-T790M Non-small Cell Lung Cancer Cells6
Caracasine, An ent-kaurane Diterpene with Proapoptotic and Pro-differentiator Activity in Human Leukaemia Cell Lines6
JHD205, A Novel Abemaciclib Derivative, Exerts Antitumor Effects on Breast Cancer by CDK4/66
Antiglycolytic Activities of Strobilanthes crispus Active Fraction and its Bioactive Components on Triple-Negative Breast Cancer Cells In Vitro6
State of the Art of IDH Inhibitors: Emerging Questions and Perspectives6
Galbanic Acid Improves Accumulation and Toxicity of Arsenic Trioxide in MT-2 Cells6
Antitumor Effects of Turmeric on OVCAR-3 Ovarian Cancer Cell Lines6
Cryptolepine Targets TOP2A and Inhibits Tumor Cell Proliferation in Breast Cancer Cells -An In vitroandIn silicoStudy6
The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance6
Antitumor Activity of Zinc Nanoparticles Synthesized with Berberine on Human Epithelial Colorectal Adenocarcinoma (Caco-2) Cells through Acting on Cox-2/NF-kB and p53 Pathways6
Novel Heterocyclic Compounds Exhibit Potent Antileukemic Activity throughSelective Induction of Apoptosis and HDAC8 Interaction in AML Cells6
Drug Targeting and Therapeutic Management of Chronic Myeloid Leukemia: Conventional and Nanotherapeutic Drug Options6
Anti-tumoral Immunity and Chemo-preventive Effectiveness of Herbal Extracts of Curcumin, Ginger, Clove and Amygdaline in Ehrlich Ascites Carcinoma-Challenging Mice6
p-Coumaric Acid Inhibits Osteosarcoma Growth by Inhibiting PI3K/Akt Signaling Pathway6
Design, Synthesis and Evaluation of Novel (E)-N'-((1-(4-chlorobenzyl)-1H-indol-3- yl)methylene)-2-(4-oxoquinazolin-3(4H)-yl)acetohydrazides as Antitumor Agents6
Targeting Telomere Shelterin Protein TPP1 with Elbasvir: Induction of Autophagy and Suppression of Esophageal Cancer Tumorigenesis6
Secretory Phospholipase A2 (sPLA2) Isozymes as Potential Targets in Tobacco Condensate- induced Colon Damage6
Design, Synthesis and Binding Affinity Evaluation of Cytochrome P450 1B1 Targeted Chelators6
Genetic and Molecular Determinants of Immunotherapy Response in Recurrent Ovarian Cancer6
Recent Advances in the Chemistry and Biology of Bakuchiol and its Derivatives: An Updated Review6
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