CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)
ArticleCitations
Meet the Editorial Board Member71
Meet the Regional Editor67
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis51
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus43
Decoding the Inter-Relationship between Sleep Disorders and Alzheimer’s Disease Pathogenesis43
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease39
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 32
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives32
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation29
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis27
Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a 27
Restless Leg Syndrome in Patients with Liver Cirrhosis! Its Frequency, Severity, and Correlation25
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment22
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation22
Drosophila melanogaster a Versatile Model of Parkinson’s Disease21
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease21
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review21
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound21
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders21
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies21
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature21
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota20
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia19
Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments19
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis19
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?18
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health18
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression18
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways18
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease18
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis17
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus17
Effectiveness and Safety Profile of Ginkgo biloba Standardized Extract (EGb761®) in Patients with Amnestic Mild Cognitive Impairment17
Autophagic Dysfunction in Dementia: Scope for Development of Potential Remedies16
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)16
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease16
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment15
Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol15
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine15
Vasospasm in Pediatric Subarachnoid Hemorrhage15
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care15
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease14
Genetic Predisposition and Severity of Eating Disorders- A Review14
Natural Products as Bioactive Agents in the Prevention of Dementia14
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach14
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review14
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock13
Dietary Nutrients and Prevention of Alzheimer’s Disease13
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases13
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings13
In-Silico Validation and Fabrication of Matrix Diffusion-Based Polymeric Transdermal Patches for Repurposing Gabapentin Hydrochloride in Neuropathic Pain13
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain13
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology13
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial13
Obesity and Depression: Common Link and Possible Targets13
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models13
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders13
Acknowledgements to Reviewers13
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?12
Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article12
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects12
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish12
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa12
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review12
Emerging Treatments for Subarachnoid Hemorrhage12
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders11
Meet the Editorial Board Member11
Arachidonic Acid Derivatives and Neuroinflammation11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review11
Acknowledgements to Reviewers11
Targeting Brain Cancer Cells by Nanorobot, a Promising Nanovehicle: New Challenges and Future Perspectives10
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases10
Lorcaserin: Worthy of Further Insights? Results from Recent Research10
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review10
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series10
One-Trial Appetitive Learning Tasks for Drug Targeting10
Rethinking Catatonia: New Insights from the Autism Spectrum10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
Benzodiazepines and Sleep Architecture: A Systematic Review10
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females9
Herbal Drug Interaction: Mechanistic Details through Pharmacokinetic Portfolio9
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis9
Pharmacotherapy in SAH: Clinical Trial Lessons9
Modulation of Huntington’s Disease in Drosophila9
Nanotechnological Advances in the Treatment of Epilepsy9
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience9
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO9
Neuroblastoma and Stem Cell Therapy: An Updated Review8
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities8
Alzheimer Disease and Sleep Disorders: Insights into the Possible Disease Connections and the Potential Therapeutic Targets (Part II)8
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights8
Deciphering the Influence of Cigarette Smoke Carcinogens on CNS Associated Biomolecules: A Computational Synergistic Approach8
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders8
Arachidonic Acid Metabolites in Neurologic Disorders8
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria8
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia8
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease8
Meet the Editorial Board Member8
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment8
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model8
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease7
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation7
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease7
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report7
Sleep Disorders Research From 1945 to 2020: A Bibliometric Analysis7
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders7
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration7
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers7
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets7
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities7
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study7
Preface7
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells7
Melatonin Alleviates Pyroptosis of Retinal Neurons Following Acute Intraocular Hypertension7
In Vivo Antidepressant Efficacy of 3-Substituted Thietane-1,1-dioxide Derivative - A Preliminary Study for Novel Anti-Depression Therapy in Neurological Disorders7
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis6
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity6
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety6
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders6
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs6
Role of Imaging Genetics in Alzheimer’s Disease: A Systematic Review and Current Update6
Role of Lipocalin-2 in N1/N2 Neutrophil Polarization After Stroke6
The Protective Effects of Pioglitazone Against Cognitive Impairment Caused by L-methionine Administration in a Rat Model6
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms6
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease6
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain6
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function6
Direct Modulation of the Gut Microbiota as a Therapeutic Approach for Alzheimer’s Disease6
How Do Abnormalities in the Cerebrospinal Fluid Impact Neuropsychology with Progressing Age?6
Meet the Editorial Board Member6
An Overview of Acute Flaccid Myelitis6
Cellular and Molecular Mechanisms of Dementia: Decoding the Causal link of Diabetes Mellitus in Alzheimer’s Disease6
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen6
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy6
A Causal-Pathway Phenotype of Chronic Fatigue Syndrome due to Hemodialysis in Patients with End-Stage Renal Disease6
Neural Basis of Dental Pulp Stem Cells and its Potential Application in Parkinson’s Disease6
A Review on Hematopoietic Stem Cell Treatment for Epilepsy6
The Possible Protective Effect of Taurine on Bisphenol Induced Structural Changes on the Cerebral Cortex of Rats: Histological and Immunohistochemical Study6
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