CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)
ArticleCitations
Meet the Editorial Board Member86
Meet the Regional Editor72
Decoding the Inter-Relationship between Sleep Disorders and Alzheimer’s Disease Pathogenesis55
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation49
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus49
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 47
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis40
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment39
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives34
Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a 32
Restless Leg Syndrome in Patients with Liver Cirrhosis! Its Frequency, Severity, and Correlation30
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease26
Targeting JNK3: An In-silico Approach to Uncover Potential Therapeutics for Alzheimer’s Disease26
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation25
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders24
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis24
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis23
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease22
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies22
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health22
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review22
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound22
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia21
Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments21
Insights into the Diagnosis, Treatment, and Management of Prion Diseases21
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature21
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?20
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways20
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis20
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease19
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus19
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease19
Effectiveness and Safety Profile of Ginkgo biloba Standardized Extract (EGb761®) in Patients with Amnestic Mild Cognitive Impairment19
Vasospasm in Pediatric Subarachnoid Hemorrhage19
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care19
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression18
Autophagic Dysfunction in Dementia: Scope for Development of Potential Remedies18
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review18
Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol18
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine18
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)18
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease17
Natural Products as Bioactive Agents in the Prevention of Dementia17
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review16
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach15
Obesity and Depression: Common Link and Possible Targets15
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial15
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock15
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models15
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings14
Genetic Predisposition and Severity of Eating Disorders- A Review14
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment14
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain14
Decoding the Gut-Brain Axis in Alzheimer’s Disease: Emerging Perspectives14
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases13
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?13
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review13
Acknowledgements to Reviewers13
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects13
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders13
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa13
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology13
Carvacrol as a Potential Neuroprotective Agent for Neurological Diseases: A Systematic Review Article13
Acknowledgements to Reviewers13
Emerging Treatments for Subarachnoid Hemorrhage13
Dietary Nutrients and Prevention of Alzheimer’s Disease13
Arachidonic Acid Derivatives and Neuroinflammation13
Rethinking Catatonia: New Insights from the Autism Spectrum12
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series12
Meet the Editorial Board Member12
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females12
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders12
Nanoparticle-Based Approaches for Glioblastoma Treatment: Advances and Future Prospects12
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases11
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone11
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO11
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review11
One-Trial Appetitive Learning Tasks for Drug Targeting11
Benzodiazepines and Sleep Architecture: A Systematic Review11
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review11
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
Pharmacotherapy in SAH: Clinical Trial Lessons11
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders10
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience10
Lorcaserin: Worthy of Further Insights? Results from Recent Research10
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease10
Nanotechnological Advances in the Treatment of Epilepsy10
Modulation of Huntington’s Disease in Drosophila10
Herbal Drug Interaction: Mechanistic Details through Pharmacokinetic Portfolio10
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities10
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis10
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm10
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment9
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights9
Melatonin Alleviates Pyroptosis of Retinal Neurons Following Acute Intraocular Hypertension9
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia9
Arachidonic Acid Metabolites in Neurologic Disorders9
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria9
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model9
Alzheimer Disease and Sleep Disorders: Insights into the Possible Disease Connections and the Potential Therapeutic Targets (Part II)9
Meet the Editorial Board Member9
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease9
In Vivo Antidepressant Efficacy of 3-Substituted Thietane-1,1-dioxide Derivative - A Preliminary Study for Novel Anti-Depression Therapy in Neurological Disorders8
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers8
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders8
Neurotoxicity of Endogenous Neurotoxin Salsolinol in Parkinson's Disease8
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells8
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study8
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities8
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial8
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration8
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets8
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report8
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation8
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease8
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease7
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms7
Role of Lipocalin-2 in N1/N2 Neutrophil Polarization After Stroke7
Meet the Editorial Board Member7
Pre-clinical Aspects and Contemporary Treatments of Parkinson’s Disease7
Structural Activity Relationship based Medicinal Perspectives of Pyrimidine Derivatives as Anti-Alzheimer’s Agents: A Comprehensive Review7
Role of Imaging Genetics in Alzheimer’s Disease: A Systematic Review and Current Update7
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety7
Preface7
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity7
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen7
Meet the Editorial Board Member7
How Do Abnormalities in the Cerebrospinal Fluid Impact Neuropsychology with Progressing Age?7
Neural Basis of Dental Pulp Stem Cells and its Potential Application in Parkinson’s Disease7
Arachidonic Acid Mediators and their Role in Neurological Disease7
Abnormality of Voltage-Gated Sodium Channels in Disease Development of the Nervous System. A Review Article7
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis7
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain7
Direct Modulation of the Gut Microbiota as a Therapeutic Approach for Alzheimer’s Disease7
An Overview of Acute Flaccid Myelitis7
Preface7
The Protective Effects of Pioglitazone Against Cognitive Impairment Caused by L-methionine Administration in a Rat Model7
The Possible Protective Effect of Taurine on Bisphenol Induced Structural Changes on the Cerebral Cortex of Rats: Histological and Immunohistochemical Study7
A Causal-Pathway Phenotype of Chronic Fatigue Syndrome due to Hemodialysis in Patients with End-Stage Renal Disease7
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function7
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy7
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders7
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