CNS & Neurological Disorders-Drug Targets

Papers
(The TQCC of CNS & Neurological Disorders-Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Meet the Editorial Board Member113
Meet the Regional Editor75
Neurobiology of Amphetamine use in Stroke Recovery Combined with Rehabilitative Training and Brain Stimulation64
Na+/HCO3− Co-transporters Inhibitor S0859 Attenuates Global Cerebral Ischemia-reperfusion Injury of the CA1 Neurons in the Gerbil’s Hippocampus61
Targeting JNK3: An In-silico Approach to Uncover Potential Therapeutics for Alzheimer's Disease60
Recent Trends in Physical Therapy Interventions and Neuromodulation Techniques to Improve Neurorehabilitation38
The Natural Neuroprotective Compounds Used in the 6-Hydroxydopamine- Induced Parkinson’s Disease in Zebrafish: The Current Applications and Perspectives37
CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment36
Memory Reflections of the Microbiota-Gut and Oligodendrocyte Axis36
Hypomyelination with Atrophy of Basal Ganglia and Cerebellum (HABC) Due to UFM1 Mutation in Roma Patients - Severe Early Encephalopathy with Stridor and Severe Hearing and Visual Impairment. A Single 34
The Potential Effect of Blueberry on Cognitive Health and Mood State based on Human Intervention Studies: Systematic Review and Mini Meta-Analysis32
Emerging Nanotechnology for the Treatment of Alzheimer’s Disease31
The Emerging Role of Marine Natural Products for the Treatment of Parkinson’s Disease30
Breaking Barriers: Advanced Pharmacological Mediators for Neuropsychiatric Disorders30
Unravelling the Role of Tyrosine and Tyrosine Hydroxylase in Parkinson’s Disease: Exploring Nanoparticle-based Gene Therapies29
Recent Advancement of Pyrazole Scaffold Based Neuroprotective Agents: A Review28
Unraveling the Triad: A Bioinformatics Analysis of the Interplay between Prenatal Depression, Inflammation, and the Gut Microbiota28
Cholinesterase Inhibitory and In Silico Toxicity Assessment of Thirty-Four Isoquinoline Alkaloids - Berberine as the Lead Compound25
GFAP and UCHL1 in Non-traumatic SAH: The Story thus Far. A Systematic Review of the Literature25
Pathological Insights into Neurodegenerative and Neurodevelopmental Disorders: Perspectives for the Development of Novel Treatment Approaches25
Monoamine Oxidase: A Potential Link in Papez Circuit to Generalized Anxiety Disorders24
Insights into the Diagnosis, Treatment, and Management of Prion Diseases24
Microbiota-Gut-Brain Axis: A Novel Paradigm in the Neurobiology of Anxiety23
Precision Neurodegeneration: Integrating Molecular Mechanisms, Biomarkers, and Targeted Therapeutics22
AI-Driven Biomarker Discovery in Motor-Related Neurodegenerative Diseases20
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus and Dementia20
Gut-Brain Axis and Neurological Disorders-How Microbiomes Affect our Mental Health20
Danshensu Enhances Cerebral Angiogenesis in Mice by Regulating the PI3K/Akt/Mtor/VEGF Signaling Axis20
Are Lysosomes Potential Therapeutic Targets for Parkinson’s Disease?19
Clozapine in a Young Female with Drug-Resistant Schizophrenia: A Case Report of Development of Serositis19
A Critical Analysis of Quercetin as the Attractive Target for the Treatment of Parkinson's Disease18
WITHDRAWN: Nigella Fixed Oil Mitigates Memory Impairment in a Rat-Aged Model of Cognitive Decline; A Pivotal Role of BDNF and CREB Signaling Pathways in the Hippocampus18
Neuropharmacological Activity of the New Piperazine Derivative 2-(4-((1- Phenyl-1H-Pyrazol-4-yl)Methyl)Piperazin-1-yl)Ethyl Acetate is Modulated by Serotonergic and GABAergic Pathways18
Vasospasm in Pediatric Subarachnoid Hemorrhage18
A Systematic Review of Updated Mechanistic Insights Towards Alzheimer’s Disease18
Breaking Through Barriers: The Transformative Potential of Nanomedicine in Overcoming Drug Delivery Challenges for Psychiatric Disorders18
An Overview of the Natural Neuroprotective Agents for the Management of Cognitive Impairment Induced by Scopolamine in Zebrafish (Danio rerio)18
Analysis of Concentrations of Monomethyl Fumarate in Patients with Multiple Sclerosis: Result from Routine Health Care17
Induced Depressive Disorder Following the First Dose of COVID-19 Vaccine17
Black phosphorus in neurological disorders: Current therapeutic applications, mechanisms, and future prospects17
High-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) Accelerates onset Time of Beneficial Treating Effects and Improves Clinical Symptoms of Depression17
IL-33 is Required for Behavioral Deficits in a Murine Model of Systemic Lupus Erythematosus Through Regulation of Microglia Glycolysis17
Solid Lipid Nanoparticle Mediated Intranasal Drug Delivery for Brain Targeting: A Comprehensive Review17
Decoding the Gut-Brain Axis in Alzheimer's Disease: Emerging Perspectives16
Effects of GABAergic Agents on Multiple Sclerosis. A Narrative Review of In-vivo Models16
Navigated Transcranial Magnetic Stimulation (nTMS) based Preoperative Planning for Brain Tumor Treatment16
Impact of Structured Physical Exercise on Adolescent Depression: A Comprehensive Meta-Analysis of RCTs15
Genetic Predisposition and Severity of Eating Disorders- A Review15
Comparison of the Sedative Effect of Ketamine, Magnesium Sulfate, and Propofol in Patients Undergoing Upper Gastrointestinal Endoscopy: Double-Blinded Randomized Clinical Trial14
Neuroprotective and Anti-Inflammatory Effects of Pioglitazone on Parkinson's Disease: A Comprehensive Narrative Review of Clinical and Experimental Findings14
Evolutionary Unmasking Resuscitative Therapeutics Potential of Centhaquin Citrate in Hypovolemic Shock14
Obesity and Depression: Common Link and Possible Targets14
Epilepsy: Modern Treatment Approaches, Clinical Aspects, and Patent Status14
Natural Products as Bioactive Agents in the Prevention of Dementia14
Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review14
The Landscape of Randomized Clinical Trial Meta-analyses on Statins for Aneurysmal Subarachnoid Hemorrhage: A Scoping Review13
Effect of Dual-task Exercise on Cognition and Dual-task Cost in the Elderly with Mild Cognitive Impairment: A Randomized Pilot Study13
Acknowledgements to Reviewers13
An Updated Review of Epigenetic-Related Mechanisms and their Contribution to Multiple Sclerosis Disease13
Hematological Consequences of Valproic Acid in Pediatric Patients: A Systematic Review with a Mechanistic Approach13
Bis-iodine-labeled Curcumin as a Potential CT Imaging Agent for β-amyloid Plaques in the Brain13
Transcription Factor Pet-1/FEV as a Potential Therapeutic Target in Anxiety and Depressive Disorders13
Targeting Blood-Brain Barrier Damage with Nanotechnology in the Fight Against Neurodegenerative Diseases13
The Effects and Regulatory Mechanism of Flavonoids from Stems and Leaves of Scutellaria baicalensis Georgi in Promoting Neurogenesis and Improving Memory Impairment Mediated by the BDNF-ERK-CREB Signa12
Sweroside Modulates Oxidative Stress and Neuroplasticity-Related Gene Expression in Scopolamine-Treated Zebrafish12
Mechanism of Glioblastoma Treatment Targeting Growth Factors: IGF-I Case Using Gene, Immune, Phytochemicals, and Nanotechnologies12
Phosphodiesterase 2 and Its Isoform A as Therapeutic Targets in the Central Nervous System Disorders12
Effects of Hesperetin Early Intervention on Brain Neurons and Microglia in APPswe/PS1dE9 Mice12
The Potential Role of Dopamine Pathways in the Pathophysiology of Depression: Current Advances and Future Aspects12
Approaches for Ear-targeted Delivery Systems in Neurosensory Disorders to avoid Chronic Hearing Loss Mediated Neurological Diseases12
Emerging Treatments for Subarachnoid Hemorrhage12
COVID-19, the Brain, and the Future: Is Infection by the Novel Coronavirus a Harbinger of Neurodegeneration?12
Role of G-Proteins and GPCR-Mediated Signalling in Neuropathophysiology12
Circadian Rhythm and Risk of Hemorrhagic Transformation after Acute Ischemic Stroke Treated with Intravenous Thrombolysis - A Systematic Review12
Nanoparticle-Based Approaches for Glioblastoma Treatment: Advances and Future Prospects11
Valproate Exposure as an In vitro Model for Studying Morpho-Molecular Features of ASD: A Systematic Review11
Lithium Chloride Rescues Dopaminergic Neurons in a Parkinson’s Disease Rat Model Challenged with Rotenone11
Acknowledgements to Reviewers11
Inhibiting Monoamine Oxidase in CNS and CVS would be a Promising Approach to Mitigating Cardiovascular Complications in Neurodegenerative Disorders11
Pharmacotherapy in SAH: Clinical Trial Lessons11
WITHDRAWN: Neurological Studies Of Herbal Medicinal Plants For The Treatment Of Memory Impairment: A Review11
Effectiveness of Highly Purified Cannabidiol in Refractory and Super-Refractory Status Epilepticus: A Case Series11
Prospects for Neurotrophic Factor-Based Early Intervention in Schizophrenia: Lessons Learned from the Effects of Antipsychotic Drugs on Cognition, Neurogenesis, and Neurotrophic Factors11
One-Trial Appetitive Learning Tasks for Drug Targeting10
Rethinking Catatonia: New Insights from the Autism Spectrum10
Focused Ultrasound-activated Extracellular Vesicles–nanoparticle Hybrids for Targeted Brain Drug Delivery: Engineering Strategies and Translational Outlook10
Cannabidiol in Epilepsy: Restoring Locomotion and Seizure Control10
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO10
Rationalizing the Use of Polyphenol Nano-formulations in the Therapy of Neurodegenerative Diseases10
Lorcaserin: Worthy of Further Insights? Results from Recent Research10
Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide10
Insights into the Molecular Mechanisms of Neurodegenerative Diseases: Exploring Molecular Pathways and the Therapeutic Potential of Rivastigmine10
Benzodiazepines and Sleep Architecture: A Systematic Review10
Neuroprotection or Sex Bias: A Protective Response to Traumatic Brain Injury in the Females9
Therapeutic Potential of Nutritional Modulators in Traumatic Brain Injury: A Systematic Review9
Circadian Rhythms and Sleep Disorders Associated to Major Depressive Disorder: Pathophysiology and Therapeutic Opportunities9
The Protective Role of L-carnitine on Psychosocial Stress-induced Changes in Gene Expression and Protein Levels of Matrix Metalloproteinases, Serum Corticosterone in a Rat Model9
Nicotine Abuse and Neurodegeneration: Novel Pharmacogenetic Targets to Aid Quitting and Reduce the Risk of Dementia9
Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers9
Role of Unani Polyherbal Formulations in the Treatment of Diseases with Special Reference to Neurodegenerative Disorders9
Traumatic Brain Injury in COVID-19 Patients with the Manifestation of Paroxysmal Sympathetic Hyperactivity and Cytokine Storm9
Nanotechnological Advances in the Treatment of Epilepsy9
Rationale and Development of Tavapadon, a D1/D5-Selective Partial Dopamine Agonist for the Treatment of Parkinson’s Disease9
Therapeutic Potential of Myricetin in the Treatment of Neurological, Neuropsychiatric, and Neurodegenerative Disorders9
Atorvastatin's Reduction of Alzheimer's Disease and Possible Alteration of Cognitive Function in Midlife as well as its Treatment9
Coenzyme Q10 in the Treatment of Attention Deficit Hyperactivity Disorder in Children: A Randomized Controlled Trial9
Peripheral Vascular Disease is Associated with Impaired Activities of Daily Living in the Elderly with Dementia: A Prospective Study9
The Peripheral Profile of the Chitinase 3-like-1 in Benign Multiple Sclerosis – A Single Centre’s Experience9
Endophenotypes and Pathway Phenotypes in Neuro-psychiatry: Crossdisciplinary Implications for Diagnosis9
Design and Molecular Docking Studies of N-Mannich Base Derivatives of Primaquine Bearing Isatin on the Targets involved in the Pathophysiology of Cerebral Malaria9
Circular RNAs in Alzheimer’s Disease: A New Perspective of Diagnostic and Therapeutic Targets9
Neurological Complications Caused by Human Immunodeficiency Virus (HIV) and Associated Opportunistic Co-infections: A Review on their Diagnosis and Therapeutic Insights9
Neurotoxicity of Endogenous Neurotoxin Salsolinol in Parkinson's Disease9
An Insight into the Role of Artificial Intelligence in the Early Diagnosis of Alzheimer’s Disease9
Preface8
Nicotine Dependence-Induced Withdrawal Syndrome: Mechanistic Insights and Therapeutic Implications8
Valproic Acid and Celecoxib Enhance the Effect of Temozolomide on Glioblastoma Cells8
Zederone Improves the Fecal Microbial Profile in Dementia Induced Rat Model: A First Report8
The Role of the cGAS-STING Pathway in Central Nervous System Diseases8
Protective Effects of Memantine Against Acute Stress-Induced Fear Memory and Synaptic Dysfunction via NMDA Receptor Antagonism8
Anaesthesia-induced Changes in Genomic Expression Leading to Neurodegeneration8
Targeting Vascular Dementia: Pharmacological Mechanisms and Therapeutic Strategies8
The Role of Ca2+ Permeable AMPA Receptors in Neurodegeneration, Neurotoxicity, and Neuroinflammation8
Neurodegenerative Disorders and the Current State, Pathophysiology, and Management of Parkinson’s Disease7
An Overview of Acute Flaccid Myelitis7
Bibliometric Analysis of Neutrophil Extracellular Traps in Stroke: Research Trends and Hotspots7
Imbalance of Th1 and Th2 Cytokines and Stem Cell Therapy in Pathological Pain7
Cyclodextrins-Phospholipids Complex Loaded Nanofibers for Improved Oral Bioavailability and Brain Targeting for Management of Stress and Anxiety7
An Insight into Medicinal Chemistry and SAR Studies of Cholinesterase and BACE-1 Inhibitors for Alzheimer's Disease7
Abnormality of Voltage-Gated Sodium Channels in Disease Development of the Nervous System. A Review Article7
Flow Diversion for the Management of Posterior Circulation’s Intracranial Aneurysms7
The Endocannabinoid System as a Biomarker for Diagnostic and Therapeutic Applications in Depression and Anxiety7
Acute Peripheral Facial Nerve Palsy in Children and Adolescents: Clinical Aspects and Treatment Modalities7
Brain-Derived Neurotrophic Factor – The Protective Agent Against Neurological Disorders7
Synergistic Roles of Neuropeptide S and Environmental Enrichment in Preclinical Huntington’s Disease Depression Models7
Meet the Editorial Board Member7
Foresee Novel Targets for Alzheimer’s Disease by Investigating Repurposed Drugs7
Integrating Synthesis, Pharmacological Activity, and Molecular Modeling to Explore 1,2,4-Triazine Fused Thiazolidin-4-one Derivatives as GABAA Receptor Modulators7
Lactose and Casein Cause Changes on Biomarkers of Oxidative Damage and Dysbiosis in an Experimental Model of Multiple Sclerosis7
Parkinson’s Disease: A Progressive Neurodegenerative Disorder and Structure-Activity Relationship of MAO Inhibitor Scaffolds as an Important Therapeutic Regimen7
Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function7
In Schizophrenia, Chronic Fatigue Syndrome- and Fibromyalgia-Like Symptoms are Driven by Breakdown of the Paracellular Pathway with Increased Zonulin and Immune Activation-Associated Neurotoxicity7
Association between Frequency of Seizures and Number of Antiseizure Medications (ASM) in Patients with Epilepsy7
How Do Abnormalities in the Cerebrospinal Fluid Impact Neuropsychology with Progressing Age?7
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