OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Innovation is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Revolutionizing Pharma: Prioritizing Industry 4.0 Implementation Challenges in the Indian Pharmaceutical Landscape Through Analytical Hierarchy Process Analysis	49
Exploring the Anxiolytic and Antidepressant-Like Effects of Citrus Maxima Oil and its Inclusion Complex: A Focus on GABAergic and Serotonergic Pathways	22
(Bio)Hybrid System of Layered Double Hydroxides and Dapsone: One-Pot Synthesis, Structural Characterization and Cell Viability	21
Application of Amorphous Solid Dispersion Technology for Improving the Physicochemical Properties, Saturation Solubility, and In Vitro Dissolution of Withania somnifera Methanolic Root Powder Extract	17
Editorial: Wrapping Up 2021 and Looking Forward to 2022	16
Development and Evaluation of Fucoidan-Based Liposomes: Targeting Smooth Muscle Cells for Atherosclerosis Treatment	14
QbD Enabled Formulation Development of Nanoemulsion of Nimodipine for Improved Biopharmaceutical Performance	14
Development of Liposomal Formulation for Controlled Delivery of Valacyclovir: an In Vitro Study	13
Comparative Study of a Novel Micro-feeder and Loss-in-weight Feeders	13
Editorial: Biopharmaceutical Innovation	11
Enhancement of Solubility and Dissolution Rate Using Tailored Rapidly Dissolving Oral Films Containing Felodipine Solid Dispersion: In Vitro Characterization and Ex Vivo Studies	11
A Gel-Free Reservoir System for Once-a-Day Ophthalmic Delivery of Timolol Maleate	10
FDA Approaches in Monitoring Drug Quality, Forces Impacting the Drug Quality, and Recent Alternative Strategies to Assess Quality in the US Drug Supply	10
Commercial Low Molecular Weight Heparins — Patent Ecosystem and Technology Paradigm for Quality Characterization	9
Ultrasound-Assisted Anti-Solvent Crystallization of Ibuprofen: Effect of Ultrasonic Treatment and Additive	9
Gene Expression Effects of the Delivery of SN-38 via Poly(D-L-lactide-co-caprolactone) Nanoparticles Comprising Dense and Collapsed Poloxamer Coronae	9
Correction to: A Comprehensive Review of Current Perspectives on Novel Drug Delivery Systems and Approaches for Lung Cancer Management	9
Fabrication of Zein-Chitosan-Zein Sandwich-Like Nanofibers Containing Teicoplanin as a Local Antibacterial Drug Delivery System	9
Statistical Design of Experiments Using R Program for the Optimization of an Extended-Release Neem Oil Matrix Tablet	9
Increasing the Stability of Pellets Containing Lycopene by Using Dual-Coating	9
23 Factorial Design and Optimization of Effervescent Floating Matrix Tablet of Neratinib	8
Self-emulsifying Drug Delivery System for Praziquantel with Enhanced Ex Vivo Permeation	8
A Novel CFD Model of SMX Static Mixer Used in Advanced Continuous Manufacturing of Active Pharmaceutical Ingredients (API)	8
The Reform of the Orphan Drug Assessment System in China	8
QbD Application for a Fixed-Dose Combination with Biowaiver Potential: Evaluations of In Vitro and In Vivo Applications	8

Impact of Process Parameters and Formulation Properties on Dissolution Performance of an Extended Release Tablet: a Multivariate Analysis	8
Design, Development, and In Vitro Characterization of Pirfenidone-Loaded Biodegradable Nanoparticles for Idiopathic Pulmonary Fibrosis	8
In Vitro Profiling of Gliclazide-Loaded Aerosil 380 Solid Dispersion–Based Tablets with Co-Processed Excipients	8
Fabrication and Evaluation of Differential Release Bilayer Tablets of Clarithromycin and Levofloxacin by 3D Printing	8
PEGylated Lipid Nanocontainers Tailored with Sunseed-Oil-Based Solidified Reverse Micellar Solution for Enhanced Pharmacodynamics and Pharmacokinetics of Metformin	8
A Systems Evaluation Model for the Development of Companion Diagnostics and Associated Molecularly Targeted Therapies	8
An Automated Jet Nebulizer with Dynamic Flow Regulation	8
Design and Evaluation of Sustained Release Bilayer Tablets of Oxcarbazepine	7
Development and Characterization of Copper Cross-Linked Freeze-Dried Bioscaffolds for Potential Wound Healing Activity	7
Blockchain for Data Originality in Pharma Manufacturing	7
Polyoxyethylene Lauryl Ether (Brij-35) and Poloxamer 407–Based Non-ionic Surfactant Vesicles for Dissolution Enhancement of Tacrolimus	7
Development, Optimization and In Vitro Characterization of Eudragit-Ganciclovir Nanosuspension or Treating Herpes Simplex Keratitis	7
Surface Functionalization of Piperine-Loaded Liposomes with Sophorolipids Improves Drug Loading and Stability	7
Gastroretentive Floating Microsponges of Mitiglinide: Design, Preparation, and Pharmacokinetic Evaluation	6
Utilizing Quality by Design to Develop and Evaluate Extended-Release Upadacitinib Tablets Incorporating a Biosynthesized Polymer	6
Novel Nanoaggregates from Phoenix dactylifera (date palm) for Inhalational Management of Cystic Fibrosis Using Dry Powder Inhalers	6
Oral Dissolving Film of Rivastigmine: Optimization Using Factorial Design	6
Exploring Potential Coformer Screening Techniques Based on Experimental and Virtual Strategies in the Manufacturing of Pharmaceutical Cocrystal of Efavirenz	6
Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin Calcium by Solid Dispersion Technique Using a Modified Natural Polymer as a Hydrophilic Carrier	6
Similar but Not Same: Impact of Structurally Similar Coformers on Co-crystallization with Telmisartan	6
Formulation, Development, and Comparative Study of Azelastine-Loaded Temperature Sensitive In Situ Gelling Micelles for Allergic Conjunctivitis	6
An Integrated Real-time Monitoring and Statistical Process Control Approach for Coating Process and Product Quality via In-line Optical Coherence Tomography	6
Design of Dual Principles Floating Osmotic Drug Delivery System of Pioglitazone Hydrochloride for Gastro-retention: In Vitro-In Vivo Evaluation	6
Liquid Crystal Nanoparticles-based Fluocinolone Acetonide Topical Gel for Atopic Dermatitis: In vitro and in vivo Study	5
Gastroprotective Efficacy of Prebiotic-based Oral Formulation of Amoxicillin	5
A Review on the Treatment and Diagnosis of Systemic Lupus Erythematosus Using Nanoparticle Systems	5
Development and Evaluation of Novel Amoxicillin and Phytic Acid-Loaded Gastro-Retentive Mucoadhesive Pectin Microparticles for the Management of Helicobacter pylori Infections	5
Optimizing Nateglinide Liquisolid Compacts: Achieving Formulation Excellence Through the Quality by Design Approach	5
Novel Ketoconazole-Loaded Niosomal Gel with Carbamide for Enhanced Topical Delivery and Skin Hydration in Fungal Infections	5
Formulation Optimization and in Vitro–in Vivo Evaluation of Alpha Lipoic Acid-Loaded Lipid–Polymer Hybrid Nanoparticles Via Design of Experiments	5
Coloaded Surface–Modified PLGA Nanoparticles for Sustained Ocular Delivery of Levofloxacin and Flurbiprofen	5
SGLT-2i: Nanoparticular-Based Strategies, Solutions, and Clinical Applications in Opposition to Low Bioavailability	5
Extrusion-Based Three-Dimensional Printing of Metronidazole Immediate Release Tablets: Impact of Processing Parameters and in Vitro Evaluation	5
Optimization of Risperidone and Quercetin Solid Lipid Nanoparticles Loaded Nasal Insitu Gel by Design Expert and Quality by Design Approach	5
Accelerated Approval for Cancer Drugs in the United States and the Clinical Evidence Required for Conversion to Regular Approval	5
Preparation and Physicochemical Characterizations of Niosomal Benzoyl Peroxide and Clindamycin Phosphate Formulation for Acne Vulgaris	5
QBD Approach for the Design, Optimization, Development, and Characterization of Naringenin-Loaded Phytosomes to Enhance Solubility and Oral Bioavailability	4
An Investigation into the Preparation, Characterization, and Therapeutic Applications of Novel Gefitinib/Capric Acid Deep Eutectic Systems	4
Moisture Content Prediction Model for Pharmaceutical Granules Using Machine Learning Techniques	4
Polymeric Film Loaded with Plinia cauliflora Peels Extract has a Differential Curative Effect on Injuries	4
Posaconazole loaded Lipid Polymer Hybrid Nanoparticles: Design and Development for Vaginal Drug Delivery	4
Improving the Intestinal Permeability of Aprepitant via Self-Microemulsifying Delivery System: In Vitro Development and in Situ Permeation Assessment	4
Passive Targeted Drug Delivery of Venlafaxine HCl to the Brain by Modified Chitosan Nanoparticles: Characterization, Cellular Safety Assessment, and In Vivo Evaluation	4
Lutein and β-Carotene Characterization in Free and Nanodispersion Forms in Terms of Antioxidant Activity and Cytotoxicity	4
Deciphering the Impact of Hyaluronic Acid Grafting Density and Molecular Weight on Paclitaxel Liposome in CD-44 Receptor Targeting	4
Formulate Lornoxicam Bio Adhesive Microspheres Using Different Polymers by Ionotropic Gelation Method and Emulsion Cross Linking Method: An Integrated Molecular Dynamics Approach	4
Unveiling the Therapeutic Potential: Okra-Derived Flavonoids in Breast Cancer Treatment	4
Hemoglobin-Polyvinyl Alcohol (Hb-PVA) Macroporous Cryogels As Swelling-Controlled Drug Delivery System Optimization and Release Kinetics of Vancomycin	4
Dissolving Microneedle Formulation of Ceftriaxone: Effect of Polymer Concentrations on Characterisation and Ex Vivo Permeation Study	4
Formulation of Nanogel Loaded with Lantana montevidensis-Incorporated Silver Nanoparticles: A Bio-Inspired Approach to Rheumatoid Arthritis Therapy	4

3D Drug Printing by Semi-Solid Extrusion Through Reusable Cartridges: Usability Evaluation	4
Nanostructured Lipid Carriers (NLCs) of Lumefantrine with Enhanced Permeation	4
Colloidal Copper Nanoparticles Loaded with Vanillic Acid as Liquid Dressings: Development, Characterisation and Evaluation	4
Integrated Continuous Process Design for Crystallisation, Spherical Agglomeration, and Filtration of Lovastatin	3
Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization	3
Studies in Development and Statistical Optimization of Levofloxacin Solid Lipid Nanoparticles for the Treatment of Tuberculosis	3
Laser Enhanced Combinatorial Chemo-photothermal Therapy of Green Synthesis Gold Nanoparticles Loaded with 6Mercaptopurine on Breast Cancer Model	3
Quality-by-Design Approach for Optimization and Processing of PLGA Polymer Film by Hot Melt Extrusion	3
Formulation, Optimization and In Vitro Studies of Flutamide-loaded Nanostructured Lipid Carrier Based Oral Drug Delivery for Enhanced Anticancer Activity	3
Advanced Machine Vision Technique for Analyzing the Blending Process of Sustained-Release Pellets	3
Effect of Curcumin-Hydroxypropyl-$$\beta$$-Cyclodextrin Complex and the Complex Loaded Gelatin Carrageenan Microparticles on the Various Chemical and Biological Properties	3
Silver Nanoparticle Synthesized with Fenugreek Leaves Is Biologically Potent than Chemically Synthesized Nanoparticle	3
Study on Effective Phase Resolution of Xiaoyao Powder and its Anti-Mammary Hyperplasia Effect	3
Improving Ampoule Opening Safety: An Exploratory Comparative Study on an Innovative Ampoule Opener	3
Influence of Nanocarrier Type on the Drug Delivery Aspects of Docetaxel: Empirical Evidences	3
Appraisal of Surelease Clear E-7–19040, an Ethylcellulose Aqueous Dispersion, as a Release Modifier for the Hydrophilic Core	3
Redesigning the Clinical Trial Development Process as a Global Pharmaceutical Firm: Gaining Velocity via Lean-Sprint	3
Compatibility Study Between Fenbendazole and Poly(Ethylene Oxide) with Application in Solid Dispersion Formulations Using Hot-Melt Extrusion	3
Fabrication of Carboxymethylcellulose-Gelatin Dissolving Microneedle Patch for Pain-Free, Efficient, and Controlled Transdermal Delivery of Insulin	3
Design and Development of Dual Release Reconstitutable Oral Suspension of Cefpodoxime Proxetil for Pediatric Patient Using Risk-Based Quality by Design Approach	3
Preparation and Evaluation of N-Acetyl D-Glucosamine Ethosomal Gel for the Treatment of Hyperpigmentation	3
Protective Effects of Supercritical CO2-Extracted Mulberry Leaf Extract against Non-Alcoholic Fatty Liver Disease in Mice	3
Saturation Solubility and Dissolution Property Improvement of Albendazole by Salt Formation Approach	3
Synergistic Effect of Nitric Oxide for Wound Healing Using Etherification of Cotton	3
Enhancing the Entrapment Efficiency of Alginate Floating Beads Using Double Emulsion Technique	3
Preparation and Characterization of Gatifloxacin-Loaded Polyacrylonitrile Nanofiber for the Management of Dry Eye Infection	3
Design, Optimization, and Characterization of Lysozyme-Loaded Poly(ɛ-Caprolactone) Microparticles for Pulmonary Delivery	3
Single-crystal Drying: Development of a Continuous Drying Prototype to Optimize Particle Flow and Residence Time Distribution	3
Quality by Design (QbD) based Formulation Optimization of Isoniazid Loaded Novel Nanostructured Lipid Carriers for Controlled Release Effect	3
Preparation and Evaluation of Dual–release Esomeprazole Magnesium Pulsed Capsules Filled with Two Kinds of Enteric-coated Pellets	3
Evaluation and Monitoring of the API Content of a Portable Near Infrared Instrument Combined with Chemometrics Based on Fluidized Bed Mixing Process	3
Editorial: The World Coming Out of Its Shell	3