OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Pharmaceutical Innovation is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Microneedle Array: Applications, Recent Advances, and Clinical Pertinence in Transdermal Drug Delivery	60
Transdermal Delivery Systems for Biomolecules	40
Particle Size Reduction Techniques of Pharmaceutical Compounds for the Enhancement of Their Dissolution Rate and Bioavailability	37
Surface Tension and Self-association Properties of Aqueous Polysorbate 20 HP and 80 HP Solutions: Insights into Protein Stabilisation Mechanisms	24
Analysis of the COVID-19 Vaccine Development Process: an Exploratory Study of Accelerating Factors and Innovative Environments	24
Implementation of QRM and DoE-Based Quality by Design Approach to VEER Chromatography Method for Simultaneous Estimation of Multiple Combined Dosage Forms of Paracetamol	24
A Review on Solid Microneedles for Biomedical Applications	23
Quality Risk Management Based: Analytical Quality by Design Approach to Eco-Friendly and Versatile Chromatography Method for Simultaneous Estimation of Multiple Fixed-Dose-Combination Products of Anti	22
Nanocrystals: Characterization Overview, Applications in Drug Delivery, and Their Toxicity Concerns	14
Dissolving Microneedle Formulation of Ceftriaxone: Effect of Polymer Concentrations on Characterisation and Ex Vivo Permeation Study	14
Twin-Screw Extruder in Pharmaceutical Industry: History, Working Principle, Applications, and Marketed Products: an In-depth Review	14
23 Full Factorial Design for Formulation and Evaluation of Floating Oral In Situ Gelling System of Piroxicam	13
Preparation and Pulsatile Release Evaluation of Teriparatide-Loaded Multilayer Implant Composed of Polyanhydride-Hydrogel Layers Using Spin Coating for the Treatment of Osteoporosis	13
Laser Enhanced Combinatorial Chemo-photothermal Therapy of Green Synthesis Gold Nanoparticles Loaded with 6Mercaptopurine on Breast Cancer Model	13
Rifampin and Cis-2-Decenoic Acid Co-entrapment in Solid Lipid Nanoparticles as an Efficient Nano-system with Potent Anti-biofilm Activities	13
Lutein-Loaded Solid Lipid Nanoparticles for Ocular Delivery: Statistical Optimization and Ex Vivo Evaluation	13
Investigation of Kinetic Drug Release Characteristics and In Vitro Evaluation of Sustained-Release Matrix Tablets of a Selective COX-2 Inhibitor for Rheumatic Diseases	12
A Comparative Study of Levocetirizine Loaded Vesicular and Matrix Type System for Topical Application: Appraisal of Therapeutic Potential against Atopic Dermatitis	12
Improving Antibacterial Efficiency of Curcumin in Magnetic Polymeric Nanocomposites	11
Development and Characterization of Starch/Gelatin Microneedle Arrays Loaded with Lecithin–Gelatin Nanoparticles of Losartan for Transdermal Delivery	11
Nano Calcium Oxide Incorporated Hydrocolloid Dressings for Wound Care	11
Nanoemulgel for Efficient Topical Delivery of Finasteride Against Androgenic Alopecia	11
Hot Melt Extrusion: an Emerging Green Technique for the Synthesis of High-Quality Pharmaceutical Cocrystals	10
Engineering Lipase Enzyme Nano-powder Using Nano Spray Dryer BÜCHI B-90: Experimental and Factorial Design Approach for a Stable Biocatalyst Production	10
Enhancement of Curcumin Solubility Using a Novel Solubilizing Polymer Soluplus®	10

An Elucidative Review to Analytically Sieve the Viability of Nanomedicine Market	10
Response Surface Methodology Optimization of Microwave-Assisted Polysaccharide Extraction from Algerian Jujube (Zizyphus lotus L.) Pulp and Peel	10
Implications of Solid Lipid Nanoparticles of Ganoderic Acid for the Treatment and Management of Hepatocellular Carcinoma	10
Systematic Development and Optimization of Teriparatide-Loaded Nanoliposomes Employing Quality by Design Approach for Osteoporosis	10
Development of a New Drug Delivery System from HELA-Derived Exosomes and the Effect of Docetaxel-Loaded Exosomes on Mitochondrial Apoptosis	10
Development and Evaluation of Letrozole-Loaded Hyaluronic Acid/Chitosan-Coated Poly(d,l-lactide-co-glycolide) Nanoparticles	10
Electrospun Poly (Vinyl Alcohol) Nanofibrous Mat Loaded with Green Propolis Extract, Chitosan and Nystatin as an Innovative Wound Dressing Material	9
Optimization and in Vitro Evaluation of Injectable Sustained-Release of Levothyroxine Using PLGA-PEG-PLGA	8
New Approach to Formulate Methotrexate-Loaded Niosomes: In Vitro Characterization and Cellular Effectiveness	8
Vesicular Formation of Trans-Ferulic Acid: an Efficient Approach to Improve the Radical Scavenging and Antimicrobial Properties	8
Modulating Gliclazide Release and Bioavailability Utilizing Multiparticulate Drug Delivery Systems	7
DoE-Based Solid Self-microemulsifying Drug Delivery System (S-SMEDDS) Approach for Improving the Dissolution Properties of Raltegravir Potassium	7
Core-Shell Nanofibers Based on Polycaprolactone/Polyvinyl Alcohol and Polycaprolactone/Collagen for Biomedical Applications	7
Efficiency of Chitosan-Coated PLGA Nanocarriers for Cellular Delivery of siRNA and CRISPR/Cas9 Complex	7
Pulmonary Delivery of Linezolid Nanoparticles for Treatment of Tuberculosis: Design, Development, and Optimization	7
In Vitro Studies of Ce-Doped Hydroxyapatite Synthesized by Sol–Gel Method for Biomedical Applications	7
A Comparative Investment Analysis of Batch Versus Continuous Pharmaceutical Manufacturing Technologies	7
Application of a System Model for Continuous Manufacturing of an Active Pharmaceutical Ingredient in an Industrial Environment	6
Polymeric Precipitation Inhibitor–Based Solid Supersaturable SMEDD Formulation of Canagliflozin: Improved Bioavailability and Anti-diabetic Activity	6
Alpha-Lipoic Acid and Cyanocobalamin Co-Loaded Nanoemulsions: Development, Characterization, and Evaluation of Stability	6
Improving Feedability of Highly Adhesive Active Pharmaceutical Ingredients by Silication	6
Recent Advances in Dissolution Testing and Their Use to Improve In Vitro–In Vivo Correlations in Oral Drug Formulations	6
The PLGA Microspheres Synthesized by a Thermosensitive Hydrogel Emulsifier for Sustained Release of Risperidone	6
Biological Evaluation of Synthesized Schiff Base-Metal Complexes Derived from Sulfisomidine	6
The Development of a Novel Pharmaceutical Formulation of D-Tagatose for Spray-Drying	6
Progress on Pharmaceutical Sciences/Pharmacy Postgraduate Education: a Bibliometric Perspective	6
Redox-Responsive and Electrically Neutral PLGA Nanoparticles for siRNA Delivery in Human Cervical Carcinoma Cells	6
Formulation and Evaluation of Cyperus esculentus (Tiger Nut) Starch-Alginate Microbeads in the Oral Delivery of Ibuprofen	6
Mitoxantrone-Loaded PLGA Nanoparticles for Increased Sensitivity of Glioblastoma Cancer Cell to TRAIL-Induced Apoptosis	5
Formulation, Optimization, and Evaluation of Ultradeformable Nanovesicles for Effective Topical Delivery of Hydroquinone	5
An Industrial Approach to Using Artificial Intelligence and Natural Language Processing for Accelerated Document Preparation in Drug Development	5
A Comprehensive Review of Current Perspectives on Novel Drug Delivery Systems and Approaches for Lung Cancer Management	5
Eugenyl Methacrylate Microsponges Loaded with Eugenol Incorporated In Situ Gel for Treatment of Periodontitis	5
Development and Evaluation of In Situ Gel of Silver Sulfadiazine for Improved Therapeutic Efficacy Against Infectious Burn Wound	5
Development, Optimization and In Vitro Characterization of Eudragit-Ganciclovir Nanosuspension or Treating Herpes Simplex Keratitis	5
Application of Simple Lattice Design and Desirability Function for Formulating and Optimizing SMEDDS of Clofazimine	5
Development and Evaluation of Thermoreversible Ethosomal Gel of Donepezil Hydrochloride for Intranasal Delivery	5
Development and Characterization of 5-Fluorouracil Solid Lipid Nanoparticles for Treatment of Colorectal Cancer	5
Use of Eudragit RS PO, HPMC K100M, Ethyl Cellulose, and Their Combination for Controlling Nicorandil Release from the Bilayer Tablets with Atorvastatin as an Immediate-Release Layer	5
Optimization and Pharmacokinetic Study of Boswellic Acid–Loaded Chitosan-Guggul Gum Nanoparticles Using Box-Behnken Experimental Design	4
Development and In Vitro Characterization of Transferrin-Decorated Nanoemulsion Utilizing Hydrophobic Ion Pairing for Targeted Cellular Uptake	4
Biopharmaceutical Industry Capability Building in India: Report from a Symposium	4
Process Design and Comparison for Batch and Continuous Manufacturing of Recombinant Adeno-Associated Virus	4
Compatibility Study Between Fenbendazole and Poly(Ethylene Oxide) with Application in Solid Dispersion Formulations Using Hot-Melt Extrusion	4
Commercial Low Molecular Weight Heparins — Patent Ecosystem and Technology Paradigm for Quality Characterization	4
Handsheet Coated by Polyvinyl Acetate as a Drug Release System	4
FDA Warning Letters: A Retrospective Analysis of Letters Issued to Pharmaceutical Companies from 2010–2020	4
Formulation Development, Optimization by Box-Behnken Design, and In Vitro Characterization of Gefitinib Phospholipid Complex Based Nanoemulsion Drug Delivery System	4
Development and Pharmaceutical Evaluation of Azelaic Acid and Vitamin E Oil-Based Nanoemulgel of Tacrolimus for Topical Application in Plaque Psoriasis	4
Preparation and Evaluation of Extended-Release Nanofibers Loaded with Pramipexole as a Novel Oral Drug Delivery System: Hybridization of Hydrophilic and Hydrophobic Polymers	4

Evaluation and Monitoring of the API Content of a Portable Near Infrared Instrument Combined with Chemometrics Based on Fluidized Bed Mixing Process	4
Process Control of Drug Product Continuous Manufacturing Operations—a Study in Operational Simplification and Continuous Improvement	4
FDA Approaches in Monitoring Drug Quality, Forces Impacting the Drug Quality, and Recent Alternative Strategies to Assess Quality in the US Drug Supply	4
pH-Sensitive Nanoparticles Developed and Optimized Using Factorial Design for Oral Delivery of Gliclazide	4
Design and Optimization of Novel Taste-Masked Medicated Chocolates of Dextromethorphan with In vitro and In vivo Taste Evaluation	4
An Eco-Friendly and Hopeful Promise Platform for Delivering Hydrophilic Wound Healing Agents in Topical Administration for Wound Disorder: Diltiazem-Loaded Niosomes	4
Quality-by-Design Approach for Optimization and Processing of PLGA Polymer Film by Hot Melt Extrusion	4
Improved Anti-inflammatory Activity and Minimum Systemic Absorption from Topical Gels of Ibuprofen Formulated by Micelle or Nanoemulsion	4
Effect of Presence of Aliphatic Glycine in the Anti-cancer Platinum Complex Structure on Human Serum Albumin Binding	4
Gossypol-Embedded Casein Nanoparticles for Potential Targeting of Ovarian Cancer: Formulation, Characterization, and Anticancer Activity	3
Blockchain for Data Originality in Pharma Manufacturing	3
Solidified Reverse Micellar Solution-Based Lipid Microparticles of Miconazole Nitrate: Formulation Design, Biopharmaceutical Characterization, and Dissolution Studies	3
Mucoadhesive Oro-Gel–Containing Chitosan Lipidic Nanoparticles for the Management of Oral Squamous Cell Carcinoma	3
Incorporation of Ursolic Acid in Liquid Crystalline Systems Improves the Antifungal Activity Against Candida Sp	3
Fluorescence-Based Detection of Cholesterol Using Inclusion Complex of Hydroxypropyl-β-Cyclodextrin and l-Tryptophan as the Fluorescence Probe	3
Preparation of Stable Clindamycin Phosphate Niosomes by Combination of Sorbitan Esters and their Ethoxylaed Derivatives	3
Development and In Vitro Evaluation of a Novel Pulsatile Drug Delivery System Containing Dexketoprofen Trometamol	3
Investigating the Effect of Particle Size on Cellular Uptake by Aggregation-Caused Quenching Probe–Encapsulating Solid Lipid Nanoparticles, Inhaled	3
Designing, Preparation, and Evaluation of Orodispersible Chitosan Anionic Salt Tablets	3
Preparation and Evaluation of Silver Nanoparticles Embedded in Muntingia calabura Leaf Extract to Cure White Piedra	3
Fabrication of Carboxymethylcellulose-Gelatin Dissolving Microneedle Patch for Pain-Free, Efficient, and Controlled Transdermal Delivery of Insulin	3
New Approaches to Assess the Transfer of Analytical and Bioanalytical Methods Using Monte Carlo Simulation and Estimation of Uncertainty	3
Impact of Process Parameters and Formulation Properties on Dissolution Performance of an Extended Release Tablet: a Multivariate Analysis	3
Development of Paediatric Formulation of Baclofen for Improved Safety and Palatability	3
Microsponge Gel Approach to Increase the Stability and Efficacy of Avobenzone as a Sun-Protective Agent	3
Feasibility of Using Light-Induced Fluorescence Spectroscopy for Low-Dose Formulations Monitoring and Control	3
Solubility and Dissolution Enhancement of Luliconazole by a Cocrystal Engineering Technique with Different Coformers	3
Fabrication and Characterization of Non-spherical Polymeric Particles	3
Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width	3
Lean Stability Case Studies—Leveraging Science- and Risk-Based Approaches to Enable Meaningful Phase Specific Pharmaceutical Stability Strategies	3
In Vitro Evaluation of Insulin Release from Chitosan-Alginate Macrobeads	3
Variable Selection Based on Gray Wolf Optimization Algorithm for the Prediction of Saponin Contents in Xuesaitong Dropping Pills Using NIR Spectroscopy	3
Development of Liposomal Formulation for Controlled Delivery of Valacyclovir: an In Vitro Study	3
Developing and Featuring Matrix Tablets by Using Gross Linseed Mucilage as a Retardant Polymer	3
Lipid Complex-Itraconazole in Thermosensitive Mucoadhesive Vaginal Gel to Enhance the Effectiveness of Therapy for Vulvovaginal Candidiasis: Formulation, Optimization, Characterization, and Ex vivo Ev	3
Nanostructured Lipid Carriers (NLCs) of Lumefantrine with Enhanced Permeation	3
A Comprehensive Review on Assessment and Key Control Strategies for Impurities in Drug Development with a Special Emphasis on Post-marketing Surveillance	3
The Effect of Adding PVP to the Binary Solid Dispersion (Indomethacin: Kaolin) on the Formation of Physically Stable Amorphous Drug	3
Development of Tamoxifen In Situ Gel Nanoemulsion for Ocular Delivery in Photoreceptor Degeneration Disorder: In Vitro Characterization, 131I-Radiolabeling, and In Vivo Biodistribution Studies	3
Can Liposomes Survive Inkjet Printing? The Effect of Jetting on Key Liposome Attributes for Drug Delivery Applications	3
Preparation of Citric Acid-Locust Bean Gum (CA-LBG) for the Disintegrating Agent of Tablet Dosage Forms	3
The Landscape of Neutralizing Monoclonal Antibodies (nAbs) for Treatment and Prevention of COVID-19	3
A Quality by Design Paradigm for Albumin-Based Nanoparticles: Formulation Optimization and Enhancement of the Antitumor Activity	3
Solid Lipid Nanoparticles as Carrier to Increase Local Bioavailability of Acitretin After Topical Administration in Psoriasis Treatment	3