OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cell Communication and Signaling is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
	109
Elevated reactive aggression in forebrain‐specific Ccn2 knockout mice	69
Targeting CCN2 protects against progressive non-alcoholic steatohepatitis in a preclinical model induced by high-fat feeding and type 2 diabetes	67
JAK3/STAT5 signaling‐triggered upregulation of PIK3CD contributes to gastric carcinoma development	55
ROR2 promotes epithelial-mesenchymal transition by hyperactivating ERK in melanoma	38
Stepping into the role of Editor‐in‐Chief of the Journal of Cell Communication and Signaling	34
Cell–cell communications: new insights into targeting efficacy of phytochemical adjuvants on tight junctions and pathophysiology of various malignancies	29
Role of the calcium‐sensing receptor in regulating vascular function	28
Trans‐Coumaryl acetate mediates GRK5/NF‐κB/Nrf2 signaling axis to ameliorate septic acute kidney injury	26
METTL3–METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneu	22
A comprehensive network map of IL-17A signaling pathway	22
	22
The antitumor effects of WNT5A against hematological malignancies	21
Novel peptide—based inhibitor for targeted inhibition of T cell function	21
CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1‐targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape	19
Adipocyte enhancer binding protein 1 knockdown alleviates osteoarthritis through inhibiting NF‐κB signaling pathway‐mediated inflammation and extracellular matrix degradation	19
Three generations of mTOR kinase inhibitors in the activation of the apoptosis process in melanoma cells	18
METTL13 facilitates cell growth and metastasis in gastric cancer via an eEF1A/HN1L positive feedback circuit	18
Scutellarin alleviates microglia‐mediated neuroinflammation and apoptosis after ischemic stroke through the PI3K/AKT/GSK3β signaling pathway	18
Prediction of cellular targets in diabetic kidney diseases with single-cell transcriptomic analysis of db/db mouse kidneys	18
ELAVL1 promotes ferroptosis via the TRIM21/HOXD8 axis to inhibit osteogenic differentiation in congenital pseudoarticular tibia‐derived mesenchymal stem cells	17
Modulation of podocyte extracellular matrix remodeling in membranous nephropathy by the NFATc3/LRRC55/BK channel pathway	17
Advances in studies of circulating microRNAs: origination, transportation, and distal target regulation	17
Dual RNase activity of IRE1 as a target for anticancer therapies	16
The regulation and functions of the matricellular CCN proteins induced by shear stress	16

Role of EGFR and FASN in breast cancer progression	16
CCN1 is predominantly elevated in human skin dermis by solar-simulated ultraviolet irradiation and accumulated in dermal extracellular matrix	15
Fat mass and obesity‐associated protein downregulation enhances N6‐methyladenosine methylation and drives ovarian cancer progression	15
The 12th international workshop on the CCN family of genes in pictures	14
Insights into the mediation of Ca2+ signaling in the promoting effects of LETX-VI on the synthesis and release of dopamine	14
Lipin-1 stability and its adipogenesis functions are regulated in contrasting ways by AKT1 and LKB1	14
Reduced expression of Collagen 17A1 in naturally aged, photoaged, and UV-irradiated human skin in vivo: Potential links to epidermal aging	13
Survival-based bioinformatics analysis to identify hub long non-coding RNAs along with lncRNA-miRNA-mRNA network for potential diagnosis/prognosis of thyroid cancer	13
Lupeol and Paclitaxel cooperate in hindering hypoxia induced vasculogenic mimicry via suppression of HIF-1α-EphA2-Laminin-5γ2 network in human oral cancer	13
Notch NICD domains form biomolecular condensates	13
TM4SF1 is a molecular facilitator that distributes cargo proteins intracellularly in endothelial cells in support of blood vessel formation	13
Cellular crosstalk of glomerular endothelial cells and podocytes in diabetic kidney disease	12
Farewell Springer… Hello Wiley	12
Role of circ_0012856 in modulating molecular pathways of diabetic peripheral neuropathy	12
Gastrokine 1 transferred by gastric cancer exosomes inhibits growth and invasion of gastric cancer cells in vitro and in vivo	12
A review on Tsukushi: mammalian development, disorders, and therapy	11
The network map of urotensin-II mediated signaling pathway in physiological and pathological conditions	11
miRNAs as short non-coding RNAs in regulating doxorubicin resistance	10
Sustained AWT1 expression by Dupuytren’s disease myofibroblasts promotes a proinflammatory milieu	10
The power of combined spatial transcriptomics and genome wide association studies (GWAS) approaches to heritable prostate cancer	10
Modeling the microenvironment special issue	10
The structure, function, and distribution of gap junctions in the retina: Life cycle in health and disease	10
Quinacrine and Curcumin in combination decreased the breast cancer angiogenesis by modulating ABCG2 via VEGF A	10
Structural insights into regulation of CCN protein activities and functions	10
The cryptic role of CXCL17/CXCR8 axis in the pathogenesis of cancers: a review of the latest evidence	10
Daphnetin alleviates inflammation and promotes autophagy via the AMPK/mTOR pathway in gouty arthritis	10
Identification of ZMYND19 as a novel biomarker of colorectal cancer: RNA-sequencing and machine learning analysis	10
Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome	10
POSTN knockdown suppresses IL‐1β‐induced inflammation and apoptosis of nucleus pulposus cells via inhibiting the NF‐κB pathway and alleviates intervertebral disc degeneration	9
GSKIP modulates cell aggregation through EMT/MET signaling rather than differentiation in SH-SY5Y human neuroblastoma cells	9
Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis	9
Evaluation of altered cell–cell communication between glia and neurons in the hippocampus of 3xTg‐AD mice at two time points	8
Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals	8
ACK1 upregulated the proliferation of head and neck squamous cell carcinoma cells by promoting p27 phosphorylation and degradation	8
Optimized multiplex immunofluorescence for the characterization of tumor immune microenvironment in neoplastic paraffin-preserved tissues	8
SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1	8
Survivin inhibition ameliorates liver fibrosis by inducing hepatic stellate cell senescence and depleting hepatic macrophage population	8
Interaction between nuclear‐translocated cellular communication network factor 2 and purine‐rich box 1 regulates the expression of fibrosis‐related genes	8