Current Molecular Pharmacology

Article	Citations
Protective Effects of Antrodia cinnamomea and Its Constituent Compound Dehydroeburicoic Acid 32 Against Alcoholic Fatty Liver Disease	81
RNA Interference-based Therapies for the Reduction of Cardiovascular Risk	57
Targeting of Lysosomes as a Therapeutic Target in Cancer	47
Deregulated MicroRNAs involved in P53 Signaling Pathway in Breast Cancer with Focus on Triple-negative Breast Cancer	34
Pain Perception and Management: Where do We Stand?	32
Obesity and Inflammation: Colorectal Cancer Engines	28
Humanin Ameliorates Late-onset Hypogonadism in Aged Male Rats	28
Alzheimer’s Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-derived Compounds in Alleviating Tau-mediated Neurodegeneration	27
Dapagliflozin Protects H9c2 Cells Against Injury Induced by Lipopolysaccharide via Suppression of CX3CL1/CX3CR1 Axis and NF-κB Activity	26
Chimeric Antigen Receptor T-cells (CARs) in Cancer Treatment	25
Mutations in Rv0678, Rv2535c, and Rv1979c Confer Resistance to Bedaquiline in Clinical Isolates of Mycobacterium Tuberculosis	25
Adipose Tissue Dysfunction Following Trauma and Hypoxia Increases the Risk of Post-Surgical Adhesion: Potential for Therapeutic Interventions	24
Grp94 Inhibitor HCP1 Suppressed the Replication of SVA in BHK-21 Cells and PK-15 Cells	23
Large language models in drug development: Current progress and future directions	23
Recombinant Human Regenerating Gene 4 Attenuates the Severity of Osteoarthritis by Promoting the Proliferation of Articular Chondrocyte in an Animal Model	22
Promising Anticancer Activity of Multitarget Cyclin Dependent Kinase Inhibitors against Human Colorectal Carcinoma Cells	21
Cytotoxic and Antitumoral Activity of N-(9H-purin-6-yl) Benzamide Derivatives and Related Water-soluble Prodrugs	21
Mechanism, Potential, and Concerns of Immunotherapy for Hepatocellular Carcinoma and Liver Transplantation	21
Effects of Modafinil (Provigil) on Memory and Learning in Experimental and Clinical Studies: From Molecular Mechanisms to Behaviour Molecular Mechanisms and Behavioural Effects	21
Anticancer Properties of Baicalin against Breast Cancer and other Gynecological Cancers: Therapeutic Opportunities based on Underlying Mechanisms	20
A Deeply Quiescent Subset of CML LSC depend on FAO yet Avoid Deleterious ROS by Suppressing Mitochondrial Complex I	19
Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways	17
Cryptotanshinone Induces Necroptosis Through Ca2+ Release and ROS Production in vitro and in vivo	17
Assessment of Antioxidant Effect of Beta-Glucan on the Whole Blood Oxidative DNA Damage with the Comet Assay in Colorectal Cancer	17
Ginger and Heart Health: From Mechanisms to Therapeutics	16

Exploring the Immune-Related Molecular Mechanisms Underlying the Comorbidity of Temporal Lobe Epilepsy and Major Depressive Disorder through Integrated Data Set Analysis	16
Targeting FGFR3 is a Useful Therapeutic Strategy for Rheumatoid Arthritis Treatment	16
PIASA, A Novel Peptide, Prevents SH-SY5Y Neuroblastoma Cells against Rotenone-induced Toxicity	15
The Involvement of the NEAT1-1/miR-873-5p/GalNAcT-I Axis in the Development of Neuroblastoma	15
BAPST. A Combo of Common Use Drugs as Metabolic Therapy for Cancer: A Theoretical Proposal	15
SK1 Inhibitor RB005 Induces Apoptosis in Colorectal Cancer Cells through SK1 Inhibition Dependent and Independent Pathway	15
A Review of the Dual Role of MicroRNA-21 in Cardiovascular Diseases: Risk Factor or a Potential Therapeutic Target	14
Prevalence of Hepatocellular Carcinoma in Men and the Contribution of Androgen and its Receptor in Pathogenesis and Therapy	14
Anti-Cancer Role of Dendrosomal Nano Solanine in Chronic Myelogenous Leukemia Cell Line through Attenuation of PI3K/AKT/mTOR Signaling Pathway and Inhibition of hTERT Expression	13
BBOX1-AS1 Activates Hedgehog Signaling Pathway to Facilitate the Proliferation and Stemness of Esophageal Squamous Cell Carcinoma Cells via miR-506-5p/EIF5A/PTCH1 Axis	13
Protective Effect of Chrysin against Chlorpyrifos-Induced Metabolic Impairment and Pancreatitis in Male Rats	13
The Therapeutic Effect and Mechanism of Qishen Yiqi Dripping Pills on Cardiovascular and Cerebrovascular Diseases and Diabetic Complications	13
The Treatment of Parkinson’s Disease with Sodium Oxybate	13
MiR-129-2-3p Inhibits Esophageal Carcinoma Cell Proliferation, Migration, and Invasion via Targeting DNMT3B	13
Tumor Organoid Model and Its Pharmacological Applications in Tumorigenesis Prevention	12
Novel Chalcone BDD-39 Mitigated Diabetic Nephropathy through the Activation of Nrf2/ARE Signaling	12
Dual Role of Pregnane X Receptor in Nonalcoholic Fatty Liver Disease	12
Sericic Acid Ameliorates DSS-induced Ulcerative Colitis in Mice by Modulating the NF-κB and Nrf2 Pathways	12
Molecular Insight into the Apoptotic Mechanism of Cancer Cells: An Explicative Review	12
Water Pipe Tobacco Smoking and Risk of Coronary Artery Disease: A Systematic Review and Meta-Analysis	12
D-allose: Molecular Pathways and Therapeutic Capacity in Cancer	11
Upregulation of miR-3130-5p Enhances Hepatocellular Carcinoma Growth by Suppressing Ferredoxin 1 : miR-3130-5p Enhances HCC Growth via Inhibiting FDX1	11
An Essential Role of c-Fos in Notch1-mediated Promotion of Proliferation of KSHV-Infected SH-SY5Y Cells	11
Hypotensive Effects of the Triterpene Oleanolic Acid for Cardiovascular Prevention	11
Gentiopicroside Ameliorated Ductular Reaction and Inflammatory Response in DDC-induced Murine Cholangiopathies Model	11
Natural Products and Cardiovascular Diseases	11
Fenbufen Alleviates Severe Acute Pancreatitis by Suppressing Caspase-1/Caspase-11-mediated Pyroptosis in Mice	10
Reduction of Genotoxicity of Carbamazepine to Human Lymphocytes by Pre-treatment with Vitamin B12	10
Thyroidectomy and PTU-Induced Hypothyroidism: Effect of L-Thyroxine on Suppression of Spatial and Non-Spatial Memory Related Signaling Molecules	10
Aloperine Alleviates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation in Macrophages and ApoE-/- Mice	10
Antinociceptive and Anti-Inflammatory Like Effects of Berberis baluchistanica	10
Inhibitory Effects of Cathepsin K Inhibitor (ODN-MK-0822) on the Paracrine Pro-Osteoclast Factors of Breast Cancer Cells	10
Evaluation of the Effect of Isobutyl Paraben and 2-ethyl Hexyl Paraben on P-glycoprotein Functional Expression in Rats: A Pharmacokinetic Study	10
Gut Microbiota Modulation for Therapeutic Management of Various Diseases: A New Perspective Using Stem Cell Therapy	9
Ketamine Metabolites-waiting in the Wings as Therapeutic Candidate for Depression?	9
Ergothioneine Suppresses Amyloid β-Induced Tau Phosphorylation and Cytotoxicity by Inactivating Glycogen Synthase Kinase-3β in Cultured Neurons	9
Molecular Insights into Agonist/Antagonist Effects on Macromolecules Involved in Human Disease Mechanisms	9
PF-04449913 Inhibits Proliferation and Metastasis of Colorectal Cancer Cells by Down-regulating MMP9 Expression through the ERK/p65 Pathway	9
PCSK9 Biomarker and Key Modulator for Cardiovascular Disorders: Heralding a New Therapeutic Era and Their Future Perspectives	9
Extracts from Artemisia annua Alleviates Myocardial Remodeling through TGF-β1/Smad2/3 Pathway and NLRP3 Inflammasome	8
Effects of Mycotoxins on Child Development	8
A Comprehensive Review of Essential Aspects of Molecular Pathophysiological Mechanisms with Emerging Interventions for Sarcopenia in Older People	8
Sanguinarine Attenuates Lung Cancer Progression via Oxidative Stress-induced Cell Apoptosis	8
Upregulation of LncRNA WT1-AS Inhibits Tumor Growth and Promotes Autophagy in Gastric Cancer via Suppression of PI3K/Akt/mTOR Pathway	8
Fenofibrate Inhibits LPS and Zymosan-induced Inflammatory Responses through Sonic Hedgehog in IMG Cells	8
Acknowledgements to Reviewers	8
Research Progress and Future Development Potential of Oridonin in Pharmacological Activities	8
Nrf2 Mediates Effect of Resveratrol in Ischemia-reperfusion Injury	8
Review of the Role of Metabolic Factors in Determining the Post-surgical Adhesion and its Therapeutic Implications, with a Focus on Extracellular Matrix and Oxidative Stress	8
Preface	8

RBM3 Accelerates Wound Healing of Skin in Diabetes through ERK1/2 Signaling	8
A Review on Post-traumatic Stress Disorder (PTSD): Symptoms, Therapies and Recent Case Studies	8
L-theanine inhibits mammalian target of rapamycin-p70S6K pathway-mediated neuroexcitation induced by N-methyl-D-aspartate	7
Neuroprotective Effects of Shogaol in Metals (Al, As and Pb) and High-fat diet-induced Neuroinflammation and Behavior in Mice	7
Current Strategies for the Management of Psoriasis with Potential Pharmacological Pathways using Herbals and Immuno-biologicals	7
Disruption of Wnt/β-catenin Pathway Elevates the Sensitivity of Gastric Cancer Cells to PD-1 Antibody	7
Anticancer Effects of Tacrolimus on Induced Hepatocellular Carcinoma in Mice	7
Influence of SGLT2 Inhibitors in Remodeling, Substrate and Ion Metabolism of Myocardium to Prevent Cardiovascular Risks: Recent Work and Advancement	7
Evaluation of Dual Inhibitory Effect of Anagliptin, Ramipril and Lisinopril on Angiotensin-Converting Enzyme and DPP-4 Activities	7
Short-term Uridine Treatment Alleviates Endoplasmic Reticulum Stress via Regulating Inflammation and Oxidative Stress in Lithium-Pilocarpine Model of Status Epilepticus	7
Retinoprotective Effects Of Crocin And Crocetin via Anti-Angiogenic Mechanism in High Glucose-Induced Human Retinal Pigment Epithelium Cells	7
Renoprotective Effect of Thymoquinone against Streptozotocin-Induced Diabetic Nephropathy: Role of NOX2 and Nrf2 Signals	7
Clozapine-induced Myocarditis: Pathophysiologic Mechanisms and Implications for Therapeutic Approaches	6
Comprehensive Analysis of SARS-COV-2 Drug Targets and Pharmacological Aspects in Treating the COVID-19	6
Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics	6
Epigenetic Regulation and Promising Therapies in Colorectal Cancer	6
Depression-like Behavior Induced by Repeated Administration of Dexamethasone to Lipopolysaccharide-inflamed Mice	6
Natural Products as PI3K/ Akt Inhibitors: Implications in Preventing Hepatocellular Carcinoma	6
A Clinical Perspective of Soluble Epoxide Hydrolase Inhibitors in Metabolic and Related Cardiovascular Diseases	6
Pharmacotherapy for SARS-CoV-2 and Seizures for Drug Repurposing Presumed on Mechanistic Targets	6
Immunomodulatory Activity of Diterpenes over Innate Immunity and Cytokine Production in a Human Alveolar Epithelial Cell Line Infected with Mycobacterium tuberculosis	6
Maprotiline Prompts an Antitumour Effect by Inhibiting PD-L1 Expression in Mice with Melanoma	6
TRIM65 in White Matter Lesions, Innate Immunity, and Tumor	6
EGFR Inhibitor CL-387785 Suppresses the Progression of Lung Adenocarcinoma	6
Combined Phloretin and Human Platelet-rich Plasma Effectively Preserved Integrities of Brain Structure and Neurological Function in Rat after Traumatic Brain Damage	6
The Regulatory Mechanism of Hypoxia-inducible Factor 1 and its Clinical Significance	6
H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma	6
Potential Therapeutic Strategies to Combat HCC	6
Bedaquiline in Drug-Resistant Tuberculosis: A Mini-Review	6
Hepatic Ischemia-reperfusion Injury: Protective Approaches and Treatment	6
IDO2-siRNA Carried by Salmonella Combined with Nifuroxazide Attenuates Melanoma Growth	6
At the Crossroads of TNF α Signaling and Cancer	6
Cilia Plays a Pivotal Role in the Hypersecretion of Airway Mucus in Mice	5
The Struggle with Rheumatism through Dracunculus vulgaris Schott: In the Light of Ethnobotanical Information	5
The Effects of Acute and Chronic Sleep Deprivation on the Immune Profile in the Rat	5
A Proteomics Study of the Subacute Toxicity of Rat Brain after Long- Term Exposure of Gelsemium elegans	5
Tangeretin in the Treatment of Pulmonary Fibrosis: Current Advances and Future Perspectives	5
Scutellarin Mediates Cytochrome P450 3A4 and 2C19 Expression via Pregnane X Receptor and Constitutive Androstane Receptor	5
Thioacetamide-Induced Norepinephrine Production by Hepatocytes is Associated with Hepatic Stellate Cell Activation and Liver Fibrosis	5
Hesperidin Exerts Anxiolytic-like Effects in Rats with Streptozotocin‐ Induced Diabetes via PKA/CREB Signaling	5
Immunopharmacological Properties of VitD3: 1, 25VitD3 Modulates Regulatory T Cells and Th17 Cells and the Cytokine Balance in PBMCs from Women with Unexplained Recurrent Spontaneous Abortion (URSA)	5
Mitochondria-targeted Uncouplers Decrease Inflammatory Reactions in Endothelial Cells by Enhancing Methylation of the ICAM1 Gene Promoter	5
Thwarting Coronavirus Infections by Tapping Host Targets: The ‘Greek Gift Sacrifice’ to Curb the Menace of Drug Resistances	5
The Role of Complement Component 3 (C3) in Psoriasis	5
Hsa_Circ_0000021 Sponges miR-3940-3p/KPNA2 Expression to Promote Cervical Cancer Progression	5
Neuropilin-2 Inhibits Drug Resistance and Progression of Melanoma Involving the MiR-331-3p Regulated Cascade	5
Toxicity, Genotoxicity, and Carcinogenicity of Isotretinoin	5
Regulatory Mechanisms of STAT3 in GBM and its Impact on TMZ Resistance	5
Polysaccharides to Combat Viruses (COVID-19) and Microbes: New updates	5
Dual Targeting of Autophagy and NF-κB Pathway by PPARγ Contributes to the Inhibitory Effect of Demethoxycurcumin on NLRP3 Inflammasome Priming	5
Effect of Chrysin and Chrysin Nanocrystals on Chlorpyrifos-Induced Dysfunction of the Hypothalamic-Pituitary-Testicular Axis in Rats	4
Probing the Ubiquitination-Mediated Function of Epithelial Sodium Channel in A549 Cells	4
Thymoquinone Attenuates Retinal Expression of Mediators and Markers of Neurodegeneration in a Diabetic Animal Model	4
Bovine lactoferrin as a Modulator of Neuroendocrine Components of Stress	4
Empagliflozin Mitigates High Glucose-Disrupted Mitochondrial Respiratory Function in H9c2 Cardiomyoblasts: A Comparative Study with NHE-1 and ROCK Inhibition	4
Apelin Receptor Dimerization and Oligomerization	4
The Mechanistic Role of Thymoquinone in Parkinson's Disease: Focus on Neuroprotection in Pre-Clinical Studies	4
Network Pharmacology and Bioinformatics of Flavonoids from Scutellaria baicalensis stems: Mitigating Aβ-Induced Cognitive Impairment in Rats via the MEK-ERK-CREB Pathway	4
Withdrawn: Variations in Altered Global Gene Expression caused by Topoisomerase II Poisons Assessed with Reference to Differences in DNA Binding	4
Impact of Nicosulfuron on Sperm Quality: Insights into Testicular Cell Apoptosis and NF-κB Signaling Pathway in Mice Testes	4
Combined Bazedoxifene and Genistein Ameliorate Ovariectomy-Induced Hippocampal Neuro-Alterations via Activating CREB/BDNF/TrkB Signaling Pathway	4
Curcumin Efficacy in a Serum/Glucose Deprivation-Induced Neuronal PC12 Injury Model	4
Anti-Diabetic Effects of Isolated Lipids from Natural Sources through Modulation of Angiogenesis	4
Effect of Edaravone on MicroRNA Expression in Exosomes after Hepatic Ischemia-reperfusion Injury	4
Chlorpyrifos with Age-Dependent Effects in Cardiac Tissue of Male Rats	4
Ferulic Acid Attenuates Kainate-induced Neurodegeneration in a Rat Poststatus Epilepticus Model	4
Moving Towards Dawn: KRas Signaling and Treatment in Pancreatic Ductal Adenocarcinoma	4
State of the Art Molecular Pharmacology, Pathogenesis and Epigenetics of 3 Major Cancers: Lung Cancer, Ovarian Cancer, and Gliomas	4
Ginkgolic Acids Confer Potential Anticancer Effects by Targeting Pro- Inflammatory and Oncogenic Signaling Molecules	4
Hypoxia Boosts Aerobic Glycolysis in Carcinoma: A Complex Process for Tumour Development	3
The Mediating Role of miR-451/ETV4/MMP13 Signaling Axis on Epithelialmesenchymal Transition in Promoting Non-small Cell Lung Cancer Progression	3
Neuroprotective Potential of Tanshinone-IIA in Mitigating Propionic Acidinduced Experimental Autism-like Behavioral and Neurochemical Alterations: Insights into c-JNK and p38MAPK Pathways	3
A Detailed Review of Molecular Pathways and Mechanisms Responsible for the Development and Aggravation of Neuropathy and Nephropathy in Diabetes	3
Agomelatine: An Astounding Sui-generis Antidepressant?	3
Key miRNAs in Modulating Aging and Longevity: A Focus on Signaling Pathways and Cellular Targets	3
The Effect of Fingolimod on Renal Ischemia/Reperfusion Injury in a Rat Model	3
Connection between JAK/STAT and PPARγ Signaling During the Progression of Multiple Sclerosis: Insights into the Modulation of T-Cells and Immune Responses in the Brain	3
Acknowledgements to Reviewers	3
Exploring the Mitochondrial Apoptotic Cell Death Landscape and Associated Components Serving as Molecular Targets, Primarily for Synthetic and Natural Drugs Targeting Oncology Therapeutics	3
Two GnRH-mitoxantrone Conjugates, Con-3 and Con-7, Target Endometrial Cancer Cells	3

Guggulsterone Promotes Nasopharyngeal Carcinoma Cells Exosomal Circfip1L1 to Mediate miR-125a-5p/VEGFA Affecting Tumor Angiogenesis	3
Recent Advances in the Glycolytic Processes Linked to Tumor Metastasis	3
Preventive and Therapeutic Aspects of Migraine for Patient Care: An Insight	3
Mycotoxin Exposure and Autism: A Systematic Review of the Molecular Mechanism	3
Stimulation of Soluble Guanylyl Cyclase (sGC) by Cinaciguat Attenuates Sepsisinduced Cardiac Injury	3
Natural Products, the Continuous Source of Therapeutic Molecules for Various Diseases: Literature Landscape Analysis	3
Artemisinin Attenuates Isoproterenol-induced Cardiac Hypertrophy via the ERK1/2 and p38 MAPK Signaling Pathways	3
Clinical Biomarkers and Novel Drug Targets to Cut Gordian Knots of Alzheimer's Disease	3
Hepatoprotective Effect of Myricetin following Lipopolysaccharide/DGalactosamine: Involvement of Autophagy and Sirtuin 1	3
Cytochrome bc1-aa3 Oxidase Supercomplex As Emerging and Potential Drug Target Against Tuberculosis	3
Doxazosin Attenuates Development of Testosterone Propionate-induced Prostate Growth by regulating TGF-β/Smad Signaling Pathway, Prostate-specific Antigen Expression and Reversing Epithelial-Mesenchyma	3
PiWi RNA in Neurodevelopment and Neurodegenerative Disorders	3
Arsenic Exposure and Amyloid Precursor Protein Processing: A Focus on Alzheimer's Disease	3
Inactivation of Parathyroid Hormone: Perspectives of Drug Discovery to Combating Hyperparathyroidism	3
Intra-tumor DKK1 and CALML5 heterogeneity as a novel biomarker for prognosis and immunotherapy response in head and neck squamous cell carcinoma	3
Polyphenols as Potential Therapeutics for Pain and Inflammation in Spinal Cord Injury	3
Pain and Inflammation Management by Using Bioactive Molecules Derived from Medicinal Plants or Natural Products	3
Antimicrobial Resistance of Clinical Klebsiella pneumoniae Isolates: Involvement of AcrAB and OqxAB Efflux Pumps	3
Endoplasmic Reticulum Stress and Renin-Angiotensin System Crosstalk in Endothelial Dysfunction	3