OOIR: Observatory of International Research

Papers

(The TQCC of Biochimica et Biophysica Acta-Gene Regulatory Mechanisms is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
From why to how; The gene expression knowledge commons	51
Bioinformatic meta-analysis of transcriptomics of developing Drosophila muscles identifies temporal regulatory transcription factors including a Notch effector	32
The nucleolus: Coordinating stress response and genomic stability	30
The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction	28
Rho-dependent transcription termination is the dominant mechanism in Mycobacterium tuberculosis	28
Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness	26
Histone acetyltransferase 1 (HAT1) acetylates hypoxia-inducible factor 2 alpha (HIF2A) to execute hypoxia response	23
HBO1, a MYSTerious KAT and its links to cancer	23
Illuminating ligand-induced dynamics in nuclear receptors through MD simulations	23
Epigenetic modification facilitates proline synthase PYCR1 aberrant expression in gastric cancer	20
UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage	18
Transposon insertion causes ctnnb2 transcript instability that results in the maternal effect zebrafish ichabod (ich) mutation	17
Genome-wide survey identifies TNNI2 as a target of KLF7 that inhibits chicken adipogenesis via downregulating FABP4	16
Transcriptional landscape of long non-coding RNAs (lncRNAs) and its implication in viral diseases	15
Dietary choline prevents high fat-induced disorder of hepatic cholesterol metabolism through SREBP-2/HNF-4α/CYP7A1 pathway in a freshwater teleost yellow catfish Pelteobagrus fulvidraco	15
Editorial Board	15
The gene regulation knowledge commons: the action area of GREEKC	14
Dealing with different conceptions of pollution in the Gene Regulation Knowledge Commons	14
Post-translational modifications of lysine-specific demethylase 1	13
Effective role of Curcumin on expression regulation of EZH2 histone methyltransferase as a dynamic epigenetic factor in osteogenic differentiation of human mesenchymal stem cells	13
Proteomic approaches to study ubiquitinomics	13
Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast cell cycle progression and expression of the Pax7 regulator	13
DDX5 (p68) orchestrates β-catenin, RelA and SP1 mediated MGMT gene expression in human colon cancer cells: Implication in TMZ chemoresistance	12
Editorial Board	12
The role of nucleotide opening dynamics in facilitated target search by DNA-repair proteins	12

Inflammation-induced nitric oxide suppresses PPARα expression and function via downregulation of Sp1 transcriptional activity in adipocytes	11
R-loop and its functions at the regulatory interfaces between transcription and (epi)genome	11
Post translational modifications at the verge of plant-geminivirus interaction	11
The versatility of the proteasome in gene expression and silencing: Unraveling proteolytic and non-proteolytic functions	11
N/C-degron pathways and inhibitor development for PROTAC applications	11
The crucial role of small heat shock proteins in prostate cancer: mechanisms and new therapeutic perspectives	10
Editorial Board	10
Differences and similarities in recognition of co-factors by Taf14	10
Regulatory systems of chicken alpha-globin gene domain suppress bidirectional transcription	10
The yeast mRNA-binding protein Cth2 post-transcriptionally modulates ergosterol biosynthesis in response to iron deficiency	10
Quantitative proteomics revealed the transition of ergosterol biosynthesis and drug transporters processes during the development of fungal fluconazole resistance	10
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?	9
Specific DNA features of the RNA polymerase I core promoter element targeted by core factor	9
Ser392 phosphorylation modulated a switch between p53 and transcriptional condensates	9
The N-degron pathway: From basic science to therapeutic applications	9
The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex	9
Insight into the mechanism of AML del(9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPα) and SPI1 (PU.1)	9
Polycomb repressive complex 1 initiates and maintains tailless repression in Drosophila embryo	9
METTL3 activates PERK-eIF2α dependent coelomocyte apoptosis by targeting the endoplasmic reticulum degradation-related protein SEL1L in echinoderms	8
Machine learning based analysis of single-cell data reveals evidence of subject-specific single-cell gene expression profiles in acute myeloid leukaemia patients and healthy controls	8
The fine-tuned crosstalk between lysine acetylation and the circadian rhythm	8
UPS regulation of gene expression and genome integrity	8
Unraveling the battle for lysine: A review of the competition among post-translational modifications	8
The moonlighting of RAD23 in DNA repair and protein degradation	8
The presence of an intron relieves gene repression caused by promoter-proximal four-bp specific sequences in yeast	8
Allelic variation within the major APOE CpG island affects its methylation in the brain of targeted replacement mice expressing human APOE	8
MicroRNA-27a-3p targeting Vangl1 and Vangl2 inhibits cell proliferation in mouse granulosa cells	8
Sirtuin4 impacts mitochondrial homeostasis in pancreatic cancer cells by reducing the stability of AlkB homolog 1 via deacetylation of the HRD1-SEL1L complex	8
WT1 regulates HOXB9 gene expression in a bidirectional way	8
Disruption of the gene regulatory programme in neurodevelopmental disorders	8
AutoFAIR-A portal for automating FAIR assessments for bioinformatics resources	8
Protein post-translational modifications: A key factor in colorectal cancer resistance mechanisms	8
KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition	7
Epigenetic oncogenesis, biomarkers and emerging chemotherapeutics for breast cancer	7
A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant	7
Ubiquitination is a major modulator for the activation of inflammasomes and pyroptosis	7
Human stem cell-specific epigenetic signatures control transgene expression	7
Navigating the tumor landscape: VEGF, MicroRNAs, and the future of cancer treatment	7
Regulation of c-Kit gene transcription selectively by bisacridine derivative through promoter dual i-motif structures	7
Isolation and characterisation of promoters from mouse genome to drive post-meiotic germ cell-specific robust gene expression for functional genomics studies	7
Metabolic substrates, histone modifications, and heart failure	7
Influence of cell volume on the gene transcription rate	7
Transcriptional responses of three slc39a/zip members (zip4, zip5 and zip9) and their roles in Zn metabolism in grass carp (Ctenopharyngodon idella)	7
The functions of FOXP transcription factors and their regulation by post-translational modifications	7
GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1	7