OOIR: Observatory of International Research

Papers

(The TQCC of Biochimica et Biophysica Acta-Gene Regulatory Mechanisms is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
From why to how; The gene expression knowledge commons	48
Bioinformatic meta-analysis of transcriptomics of developing Drosophila muscles identifies temporal regulatory transcription factors including a Notch effector	31
Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness	30
The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction	28
Rho-dependent transcription termination is the dominant mechanism in Mycobacterium tuberculosis	27
Illuminating ligand-induced dynamics in nuclear receptors through MD simulations	25
Transcriptional landscape of long non-coding RNAs (lncRNAs) and its implication in viral diseases	23
The nucleolus: Coordinating stress response and genomic stability	23
HBO1, a MYSTerious KAT and its links to cancer	23
Histone acetyltransferase 1 (HAT1) acetylates hypoxia-inducible factor 2 alpha (HIF2A) to execute hypoxia response	20
UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage	16
Genome-wide survey identifies TNNI2 as a target of KLF7 that inhibits chicken adipogenesis via downregulating FABP4	16
Dietary choline prevents high fat-induced disorder of hepatic cholesterol metabolism through SREBP-2/HNF-4α/CYP7A1 pathway in a freshwater teleost yellow catfish Pelteobagrus fulvidraco	16
Dealing with different conceptions of pollution in the Gene Regulation Knowledge Commons	15
Editorial Board	15
Epigenetic modification facilitates proline synthase PYCR1 aberrant expression in gastric cancer	15
Differential requirements for different subfamilies of the mammalian SWI/SNF chromatin remodeling enzymes in myoblast cell cycle progression and expression of the Pax7 regulator	13
Proteomic approaches to study ubiquitinomics	13
Post-translational modifications of lysine-specific demethylase 1	13
The gene regulation knowledge commons: the action area of GREEKC	13
Editorial Board	12
Effective role of Curcumin on expression regulation of EZH2 histone methyltransferase as a dynamic epigenetic factor in osteogenic differentiation of human mesenchymal stem cells	12
The role of nucleotide opening dynamics in facilitated target search by DNA-repair proteins	11
Post translational modifications at the verge of plant-geminivirus interaction	11
The versatility of the proteasome in gene expression and silencing: Unraveling proteolytic and non-proteolytic functions	11

Inflammation-induced nitric oxide suppresses PPARα expression and function via downregulation of Sp1 transcriptional activity in adipocytes	11
N/C-degron pathways and inhibitor development for PROTAC applications	11
DDX5 (p68) orchestrates β-catenin, RelA and SP1 mediated MGMT gene expression in human colon cancer cells: Implication in TMZ chemoresistance	11
R-loop and its functions at the regulatory interfaces between transcription and (epi)genome	11
The yeast mRNA-binding protein Cth2 post-transcriptionally modulates ergosterol biosynthesis in response to iron deficiency	10
The crucial role of small heat shock proteins in prostate cancer: mechanisms and new therapeutic perspectives	10
Polycomb repressive complex 1 initiates and maintains tailless repression in Drosophila embryo	10
Regulatory systems of chicken alpha-globin gene domain suppress bidirectional transcription	10
Editorial Board	10
Differences and similarities in recognition of co-factors by Taf14	10
Quantitative proteomics revealed the transition of ergosterol biosynthesis and drug transporters processes during the development of fungal fluconazole resistance	10
The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex	9
Specific DNA features of the RNA polymerase I core promoter element targeted by core factor	9
EBV infection alters DNA methylation in primary human colon cells: A path to inflammation and carcinogenesis?	9
The N-degron pathway: From basic science to therapeutic applications	9
Insight into the mechanism of AML del(9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPα) and SPI1 (PU.1)	9
METTL3 activates PERK-eIF2α dependent coelomocyte apoptosis by targeting the endoplasmic reticulum degradation-related protein SEL1L in echinoderms	9
Ser392 phosphorylation modulated a switch between p53 and transcriptional condensates	9
Sirtuin4 impacts mitochondrial homeostasis in pancreatic cancer cells by reducing the stability of AlkB homolog 1 via deacetylation of the HRD1-SEL1L complex	8
The fine-tuned crosstalk between lysine acetylation and the circadian rhythm	8
Disruption of the gene regulatory programme in neurodevelopmental disorders	8
MicroRNA-27a-3p targeting Vangl1 and Vangl2 inhibits cell proliferation in mouse granulosa cells	8
The presence of an intron relieves gene repression caused by promoter-proximal four-bp specific sequences in yeast	8
WT1 regulates HOXB9 gene expression in a bidirectional way	8
Allelic variation within the major APOE CpG island affects its methylation in the brain of targeted replacement mice expressing human APOE	8
AutoFAIR-A portal for automating FAIR assessments for bioinformatics resources	8
Unraveling the battle for lysine: A review of the competition among post-translational modifications	8
The moonlighting of RAD23 in DNA repair and protein degradation	8
Machine learning based analysis of single-cell data reveals evidence of subject-specific single-cell gene expression profiles in acute myeloid leukaemia patients and healthy controls	8
UPS regulation of gene expression and genome integrity	8
KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition	8
GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1	7
Human stem cell-specific epigenetic signatures control transgene expression	7
Transcriptional responses of three slc39a/zip members (zip4, zip5 and zip9) and their roles in Zn metabolism in grass carp (Ctenopharyngodon idella)	7
Metabolic substrates, histone modifications, and heart failure	7
Protein post-translational modifications: A key factor in colorectal cancer resistance mechanisms	7
Ubiquitination is a major modulator for the activation of inflammasomes and pyroptosis	7
Epigenetic oncogenesis, biomarkers and emerging chemotherapeutics for breast cancer	7
Influence of cell volume on the gene transcription rate	7
Navigating the tumor landscape: VEGF, MicroRNAs, and the future of cancer treatment	7
Isolation and characterisation of promoters from mouse genome to drive post-meiotic germ cell-specific robust gene expression for functional genomics studies	7
Insights into the target-directed miRNA degradation mechanism in Drosophila ovarian cell culture	7