OOIR: Observatory of International Research

Papers

(The median citation count of Inflammation and Regeneration is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Matrix remodeling associated 7 proteins promote cutaneous wound healing through vimentin in coordinating fibroblast functions	121
Role of circulating molecules in age-related cardiovascular and metabolic disorders	89
The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?	64
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery	57
Marine-derived microbes and molecules for drug discovery	53
Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19	45
A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation	45
Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostaglandin E synthase-1	39
Characterization of the human gut virome in metabolic and autoimmune diseases	38
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury	38
A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1	32
Mechanisms of cooperative cell-cell interactions in skeletal muscle regeneration	32
Significance of the multiomics approach to elucidate disease mechanisms in humans	30
Inter-organ communication involved in metabolic regulation at the whole-body level	30
ALKBH5-mediated m6A demethylation fuels cutaneous wound re-epithelialization by enhancing PELI2 mRNA stability	30
Versatile extracellular vesicle-mediated information transfer: intercellular synchronization of differentiation and of cellular phenotypes, and future perspectives	29
Resolving the conflicts around Par2 opposing roles in regeneration by comparing immune-mediated and toxic-induced injuries	29
Investigation of immune-related diseases using patient-derived induced pluripotent stem cells	28
Therapy-resistant nature of cancer stem cells in view of iron metabolism	28
Macrophage depletion in inflamed rat knees prevents the activation of synovial mesenchymal stem cells by weakening Nampt and Spp1 signaling	26
Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy	25
Association of cellular immunity with severity of COVID-19 from the perspective of antigen-specific memory T cell responses and cross-reactivity	25
Enhancer RNA commits osteogenesis via microRNA-3129 expression in human bone marrow-derived mesenchymal stem cells	25
Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration	22
Destruction and regeneration in bone and cartilage	22

Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications	21
Multi-omics approach to precision medicine for immune-mediated diseases	21
The role of Staphylococcus aureus quorum sensing in cutaneous and systemic infections	21
Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis	20
Metabolic network of the gut microbiota in inflammatory bowel disease	20
Increased neutrophils in inflammatory bowel disease accelerate the accumulation of amyloid plaques in the mouse model of Alzheimer’s disease	20
Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease	20
Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus	19
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	19
Unveiling dynamic interactions: in vivo imaging chronicles inflammation and regeneration in living organisms	19
Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis	19
Transition of clinical and basic studies on liver cirrhosis treatment using cells to seek the best treatment	18
Inactivation of the CMAH gene and deficiency of Neu5Gc play a role in human brain evolution	18
Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion	17
Therapeutic non-invasive brain treatments in Alzheimer’s disease: recent advances and challenges	17
Immune-instructive copolymer scaffolds using plant-derived nanoparticles to promote bone regeneration	17
A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo	16
A niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells	16
Mesenchymal stromal cells in the thymus	16
Hippo pathway in cell–cell communication: emerging roles in development and regeneration	15
Proteomics of blood extracellular vesicles in inflammatory respiratory diseases for biomarker discovery and new insights into pathophysiology	15
Studies on immune regulation for allogeneic iPSC-based transplantation	15
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice	15
TNF-α and IFN-γ prestimulation enhances the therapeutic efficacy of human amniotic epithelial stem cells in chemotherapy-induced ovarian dysfunction	15
Designer cell therapy for tissue regeneration	15
Cell fusion dynamics: mechanisms of multinucleation in osteoclasts and macrophages	14
Intravital imaging of immune responses in intestinal inflammation	14
Autocrine insulin-like growth factor 2 signaling as a potential target in the associated development of pulmonary emphysema and cancer in smokers	14
Entering the era of precision medicine through multiomics approach	14
Expression of factor XIII originating from synovial fibroblasts and macrophages induced by interleukin-6 signaling	13
Designer immune cells	13
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	13
A disease-specific iPS cell resource for studying rare and intractable diseases	13
Gene editing technology to improve antitumor T-cell functions in adoptive immunotherapy	13
Multiomic technologies for analyses of inborn errors of immunity: from snapshot of the average cell to dynamic temporal picture at single-cell resolution	13
Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA	13
Peripheral and central regulation of neuro–immune crosstalk	12
Ca2+ signaling in vascular smooth muscle and endothelial cells in blood vessel remodeling: a review	11
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition	11
Subarachnoid hemorrhage triggers neuroinflammation of the entire cerebral cortex, leading to neuronal cell death	11
CX3CR1+ age-associated CD4+ T cells contribute to synovial inflammation in late-onset rheumatoid arthritis	11
Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases	11
A review of current status of cell-based therapies for aortic aneurysms	11
Multi-organ frailty is enhanced by periodontitis-induced inflammaging	11
Deletion of TP signaling in macrophages delays liver repair following APAP-induced liver injury by reducing accumulation of reparative macrophage and production of HGF	10
Identification of molecular subtypes based on inflammatory response in lower-grade glioma	10
Emilin2 marks the target region for mesenchymal cell accumulation in bone regeneration	10
The role of lymphatics in intestinal inflammation	9
Cross-talk between nervous, immune, and metabolic systems	9
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	9

A short review on lymphatic endothelial cell heterogeneity	9
Regeneration of joint surface defects by transplantation of allogeneic cartilage: application of iPS cell-derived cartilage and immunogenicity	9
Localization and movement of Tregs in gastrointestinal tract: a systematic review	8
Efficacy and risk of mRNA vaccination in patients with autoimmune inflammatory rheumatic diseases	8
Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci	8
Transforming growth factor-β-induced secretion of extracellular vesicles from oral cancer cells evokes endothelial barrier instability via endothelial-mesenchymal transition	8
Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease—a multi-faceted approach to fever of unknown origin of childhood	8
Umbilical cord blood and cord tissue banking as somatic stem cell resources to support medical cell modalities	8
Cardiac regeneration by direct reprogramming in this decade and beyond	8
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	8
The gut-liver axis in hepatobiliary diseases	7
JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors	7
Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model	7
Thymic self-antigen expression for immune tolerance and surveillance	7
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	7
Amelioration of liver fibrosis with autologous macrophages induced by IL-34-based condition	7
Neural repair mechanisms after ischemic stroke	7
Statistical genetics and polygenic risk score for precision medicine	7
Editorial: Towards a better understanding of the physiology of the lymphatics	7
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	7
Correction: Immune-mediated myogenesis and acetylcholine receptor clustering promote a slow disease progression in ALS mouse models	7
Correction: Autoinflammatory disease: clinical perspectives and therapeutic strategies	7
Regulation of inflammatory diseases via the control of mRNA decay	6
VEGFR1-tyrosine kinase signaling in pulmonary fibrosis	6
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	6
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction	6
Axon guidance molecules in immunometabolic diseases	6
Osteoclast biology in the single-cell era	6
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization	6
Morphological heterogeneity description enabled early and parallel non-invasive prediction of T-cell proliferation inhibitory potency and growth rate for facilitating donor selection of human mesenchy	5
Endothelial-specific depletion of TGF-β signaling affects lymphatic function	5
State-of-the-art liver disease research using liver-on-a-chip	5
CX3CL1-CX3CR1 axis protects retinal ganglion cells by inhibiting microglia activation in a distal optic nerve trauma model	5
Current understanding of T cell immunity against SARS-CoV-2	5
Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model	5
Isolation and characterization of neural stem/progenitor cells in the subventricular zone of the naked mole-rat brain	5
Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss	5