OOIR: Observatory of International Research

Papers

(The median citation count of Inflammation and Regeneration is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration	205
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery	135
Single-pixel imaging flow cytometry for biomedical research	110
Macrophage depletion in inflamed rat knees prevents the activation of synovial mesenchymal stem cells by weakening Nampt and Spp1 signaling	83
Peripheral and central regulation of neuro–immune crosstalk	74
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	72
Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells	65
Cross-talk between nervous, immune, and metabolic systems	61
Correction: Autoinflammatory disease: clinical perspectives and therapeutic strategies	59
APJ regulates the balance between self-renewal and differentiation of vascular endothelial stem cells	59
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	55
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	52
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	47
Umbilical cord blood and cord tissue banking as somatic stem cell resources to support medical cell modalities	46
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization	42
Acomys cahirinus develop lung stroma distortion but not fibrosis after bleomycin-induced injury	42
Recent advances in immunological mechanisms and murine disease models of idiopathic inflammatory myopathies	39
Immune cell trafficking: a novel perspective on the gut-skin axis	39
IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury	37
Rapid and high-purity differentiation of human medium spiny neurons reveals LMNB1 hypofunction and subtype necessity in modeling Huntington’s disease	34
Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2	33
Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury	31
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	30
In vivo imaging of inflammatory response in cancer research	30
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	30

A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis	29
Role of the Hippo pathway in liver regeneration and repair: recent advances	28
Advances in vascular endothelial cell-mediated regulation of satellite cell repair and regeneration	28
Autoinflammatory disease: clinical perspectives and therapeutic strategies	28
Accelerating corneal wound healing using exosome-mediated targeting of NF-κB c-Rel	27
Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion	27
Innate immune recognition against SARS-CoV-2	25
Par2-mediated responses in inflammation and regeneration: choosing between repair and damage	25
Pathophysiological functions of semaphorins in the sympathetic nervous system	25
Adipose-derived mesenchymal stem cell therapy for connective tissue diseases and complications	25
Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy	24
Characterization of the human gut virome in metabolic and autoimmune diseases	23
Destruction and regeneration in bone and cartilage	23
Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis	23
A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation	22
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	22
A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1	21
From bench to bedside: the role of gastrointestinal stem cells in health and disease	21
Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications	21
Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus	20
A review of current status of cell-based therapies for aortic aneurysms	19
A disease-specific iPS cell resource for studying rare and intractable diseases	18
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice	17
Intravital imaging of immune responses in intestinal inflammation	17
Functional diversity of disorder-specific macrophages involved in various diseases	16
Hippo pathway in cell–cell communication: emerging roles in development and regeneration	16
Innate immune memory in macrophage differentiation and cardiovascular diseases	16
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	15
Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model	15
Editorial: Towards a better understanding of the physiology of the lymphatics	15
NRP2+ human mesenchymal stem cells have stemness-associated properties	15
Chronological transitions of hepatocyte growth factor treatment effects in spinal cord injury tissue	15
Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease—a multi-faceted approach to fever of unknown origin of childhood	15
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	15
A novel prostaglandin I2 agonist, ONO-1301, attenuates liver inflammation and suppresses fibrosis in non-alcoholic steatohepatitis model mice	15
Harnessing the potential of gene editing technology for CAR-T cell therapy of solid tumors	14
Cartilage evaluation by ultrasonography in patients with rheumatoid arthritis: a scoping review	14
Helicobacter pylori infection in the stomach induces neuroinflammation: the potential roles of bacterial outer membrane vesicles in an animal model of Alzheimer’s disease	14
SPARC activates p38γ signaling to promote PFKFB3 protein stabilization and contributes to keloid fibroblast glycolysis	13
Potential therapeutic applications of stem cells in animal models of ocular affections	13
Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy	13
Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice	13
Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells	13
Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions	13
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation	13
Anti-survival of motor neuron antibodies in rheumatic and musculoskeletal diseases: prevalence, clinical associations, and biomarker potential, with novel insights into disease activity in SLE	13
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease	13
Ex vivo lung-organoid model for aberrant basaloid cell induction and activation	12
The oral-gut axis: a missing piece in the IBD puzzle	12
Inter-organ communication involved in metabolic regulation at the whole-body level	12

Marine-derived microbes and molecules for drug discovery	12
Versatile extracellular vesicle-mediated information transfer: intercellular synchronization of differentiation and of cellular phenotypes, and future perspectives	12
Significance of the multiomics approach to elucidate disease mechanisms in humans	12
Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease	11
The role of Staphylococcus aureus quorum sensing in cutaneous and systemic infections	11
Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19	11
Designer immune cells	11
Matrix remodeling associated 7 proteins promote cutaneous wound healing through vimentin in coordinating fibroblast functions	11
Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion	11
Cell fusion dynamics: mechanisms of multinucleation in osteoclasts and macrophages	10
Identification of molecular subtypes based on inflammatory response in lower-grade glioma	10
The impact of T cells on immune-related liver diseases: an overview	10
Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA	10
Dendritic cell heterogeneity and its role in connective tissue diseases	10
Osteoclast biology in the single-cell era	9
Function of alveolar macrophages in lung cancer microenvironment	9
Duration of SARS-CoV-2 RNA positivity from various specimens and clinical characteristics in patients with COVID-19: a systematic review and meta-analysis	9
Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss	9
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction	9
A novel cell-free intrathecal approach with PRP for the treatment of spinal cord multiple sclerosis in cats	9
The Ragulator complex: delving its multifunctional impact on metabolism and beyond	9
Recent advances in Raman probes for multiplexed bioimaging	9
Multi-organ frailty is enhanced by periodontitis-induced inflammaging	9
Neuroplasticity related to chronic pain and its modulation by microglia	9
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia	9
Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation	8
Maternal immunoglobulins are distributed in the offspring’s brain to support the maintenance of cortical interneurons in the postnatal period	8
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury	8
Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration	8
Effect of aging on the formation and growth of colonic epithelial organoids by changes in cell cycle arrest through TGF-β-Smad3 signaling	8
Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment	8
Optimization of transplantation methods using isolated mesenchymal stem/stromal cells: clinical trials of inflammatory bowel diseases as an example	8
Autocrine insulin-like growth factor 2 signaling as a potential target in the associated development of pulmonary emphysema and cancer in smokers	7
Mesenchymal stromal cells in the thymus	7
Preventive role of CD163-positive macrophages in postoperative peritoneal adhesions	7
Prime-boost-type PspA3 + 2 mucosal vaccine protects cynomolgus macaques from intratracheal challenge with pneumococci	7
Studies on immune regulation for allogeneic iPSC-based transplantation	7
Stem cell modelling of osteoarthritis using an organ-on-a-chip approach	7
Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseases	7
Regulation of intestinal epithelial homeostasis by mesenchymal cells	7
Neural repair mechanisms after ischemic stroke	7
A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo	7
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition	7
Metabolic network of the gut microbiota in inflammatory bowel disease	7
Lactobacillus reuteri NCHBL-005 improves wound healing by promoting the activation of fibroblasts through TLR2/MAPK signaling	7
Evaluation of immunosuppression protocols for MHC-matched allogeneic iPS cell-based transplantation using a mouse skin transplantation model	7