OOIR: Observatory of International Research

Papers

(The median citation count of Inflammation and Regeneration is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery	157
Macrophage depletion in inflamed rat knees prevents the activation of synovial mesenchymal stem cells by weakening Nampt and Spp1 signaling	134
Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration	101
Single-pixel imaging flow cytometry for biomedical research	94
Ability to form Sox17-induced hematopoietic cell clusters varies among distinct hematopoietic sites during development	72
Peripheral and central regulation of neuro–immune crosstalk	69
Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells	69
Umbilical cord blood and cord tissue banking as somatic stem cell resources to support medical cell modalities	65
APJ regulates the balance between self-renewal and differentiation of vascular endothelial stem cells	65
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization	48
Correction: Autoinflammatory disease: clinical perspectives and therapeutic strategies	47
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	46
Cross-talk between nervous, immune, and metabolic systems	46
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	45
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	43
Acomys cahirinus develop lung stroma distortion but not fibrosis after bleomycin-induced injury	40
Adaptive-like CAR-iPSC-CD4⁺ T cells outperform CD8⁺ counterparts in sustained ALL control	38
Immune cell trafficking: a novel perspective on the gut-skin axis	37
Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury	34
Transcutaneous auricular vagus nerve stimulation promotes recovery from otitis media by activating the α7nAChR-mediated anti-inflammatory pathway	34
Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2	32
In vivo imaging of inflammatory response in cancer research	32
Rapid and high-purity differentiation of human medium spiny neurons reveals LMNB1 hypofunction and subtype necessity in modeling Huntington’s disease	30
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	30
Recent advances in immunological mechanisms and murine disease models of idiopathic inflammatory myopathies	30

Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	30
IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury	30
Enhanced nerve regeneration after transplantation of NCAM-positive neural crest-like cells derived from human iPSC	29
A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis	29
Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion	28
Par2-mediated responses in inflammation and regeneration: choosing between repair and damage	27
Senescence of T cells and organ aging	27
Advances in vascular endothelial cell-mediated regulation of satellite cell repair and regeneration	27
Innate immune recognition against SARS-CoV-2	26
Autoinflammatory disease: clinical perspectives and therapeutic strategies	26
Pathophysiological functions of semaphorins in the sympathetic nervous system	25
Role of the Hippo pathway in liver regeneration and repair: recent advances	25
Accelerating corneal wound healing using exosome-mediated targeting of NF-κB c-Rel	25
Adipose-derived mesenchymal stem cell therapy for connective tissue diseases and complications	24
A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1	23
Destruction and regeneration in bone and cartilage	23
Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications	23
From bench to bedside: the role of gastrointestinal stem cells in health and disease	22
Effects of intranasal long-acting insulin pretreatment on postoperative delirium and the NLRP3/caspase-1/IL-1β pathway in older patients with esophageal cancer	21
Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy	20
Characterization of the human gut virome in metabolic and autoimmune diseases	20
Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis	19
Reengineering statin therapy to protect skeletal muscle: nanocarrier strategies for mitigating mitochondrial dysfunction and myotoxicity	19
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	19
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice	19
Intravital imaging of immune responses in intestinal inflammation	18
A disease-specific iPS cell resource for studying rare and intractable diseases	17
A review of current status of cell-based therapies for aortic aneurysms	17
Functional diversity of disorder-specific macrophages involved in various diseases	17
Hippo pathway in cell–cell communication: emerging roles in development and regeneration	17
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	16
Innate immune memory in macrophage differentiation and cardiovascular diseases	16
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	16
Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease—a multi-faceted approach to fever of unknown origin of childhood	16
NRP2+ human mesenchymal stem cells have stemness-associated properties	16
Cellular niches for hematopoietic stem cells in bone marrow under normal and malignant conditions	15
Chronological transitions of hepatocyte growth factor treatment effects in spinal cord injury tissue	15
Helicobacter pylori infection in the stomach induces neuroinflammation: the potential roles of bacterial outer membrane vesicles in an animal model of Alzheimer’s disease	15
Potential therapeutic applications of stem cells in animal models of ocular affections	15
Cartilage evaluation by ultrasonography in patients with rheumatoid arthritis: a scoping review	15
Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model	15
Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice	15
Anti-survival of motor neuron antibodies in rheumatic and musculoskeletal diseases: prevalence, clinical associations, and biomarker potential, with novel insights into disease activity in SLE	15
Harnessing the potential of gene editing technology for CAR-T cell therapy of solid tumors	15
Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation	14
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease	14
Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy	14
Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells	14
Ex vivo lung-organoid model for aberrant basaloid cell induction and activation	13
The oral-gut axis: a missing piece in the IBD puzzle	13

Significance of the multiomics approach to elucidate disease mechanisms in humans	13
SPARC activates p38γ signaling to promote PFKFB3 protein stabilization and contributes to keloid fibroblast glycolysis	13
Diagnostic potential of cryptic exon-derived peptides in serum extracellular vesicles for sporadic amyotrophic lateral sclerosis	13
Marine-derived microbes and molecules for drug discovery	12
Next-generation proteomics of serum extracellular vesicles combined with single-cell RNA sequencing identifies MACROH2A1 associated with refractory COVID-19	12
Designer immune cells	12
The role of Staphylococcus aureus quorum sensing in cutaneous and systemic infections	12
Versatile extracellular vesicle-mediated information transfer: intercellular synchronization of differentiation and of cellular phenotypes, and future perspectives	12
Inter-organ communication involved in metabolic regulation at the whole-body level	12
Matrix remodeling associated 7 proteins promote cutaneous wound healing through vimentin in coordinating fibroblast functions	12
Cell fusion dynamics: mechanisms of multinucleation in osteoclasts and macrophages	11
Osteoclast biology in the single-cell era	11
Recent advances in Raman probes for multiplexed bioimaging	11
Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion	11
Multi-organ frailty is enhanced by periodontitis-induced inflammaging	11
Identification of molecular subtypes based on inflammatory response in lower-grade glioma	11
Dendritic cell heterogeneity and its role in connective tissue diseases	11
The impact of T cells on immune-related liver diseases: an overview	11
Enhancement of bone regeneration by coadministration of angiogenic and osteogenic factors using messenger RNA	11
Natural killer cells: gatekeepers of healthy aging in longevity medicine	11
Extracellular vesicles from dental pulp mesenchymal stem cells modulate macrophage phenotype during acute and chronic cardiac inflammation in athymic nude rats with myocardial infarction	10
Effect of JAK inhibitors on the three forms of bone damage in autoimmune arthritis: joint erosion, periarticular osteopenia, and systemic bone loss	10
Duration of SARS-CoV-2 RNA positivity from various specimens and clinical characteristics in patients with COVID-19: a systematic review and meta-analysis	10
Pivotal contribution of super-enhancer-driven KLF6 expression to the adipogenesis of human adipose-derived stem cells	10
CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia	10
Amphiregulin attenuates sepsis-induced myocardial dysfunction by maintaining the localization of connexin43	10
Microbiota-derived D-amino acids in intestinal homeostasis and inflammatory bowel disease	10
Function of alveolar macrophages in lung cancer microenvironment	10
Effect of aging on the formation and growth of colonic epithelial organoids by changes in cell cycle arrest through TGF-β-Smad3 signaling	10
A novel cell-free intrathecal approach with PRP for the treatment of spinal cord multiple sclerosis in cats	10
Accelerating skin regeneration and wound healing by controlled ROS from photodynamic treatment	9
Correction: Th9 cells at the intersection of IBD and colorectal cancer: a context-dependent factor in carcinogenesis	9
Optimization of transplantation methods using isolated mesenchymal stem/stromal cells: clinical trials of inflammatory bowel diseases as an example	9
Maternal immunoglobulins are distributed in the offspring’s brain to support the maintenance of cortical interneurons in the postnatal period	9
A spatiotemporal atlas of senescence-associated secretory phenotype in fracture healing: stage-dependent mechanisms and therapeutic windows	9
Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration	9
The Ragulator complex: delving its multifunctional impact on metabolism and beyond	9
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury	8
Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation	8
Stem cell modelling of osteoarthritis using an organ-on-a-chip approach	8
Metabolic network of the gut microbiota in inflammatory bowel disease	8
Mesenchymal stromal cells in the thymus	8
Studies on immune regulation for allogeneic iPSC-based transplantation	8
Autocrine insulin-like growth factor 2 signaling as a potential target in the associated development of pulmonary emphysema and cancer in smokers	8