OOIR: Observatory of International Research

Papers

(The TQCC of Inflammation and Regeneration is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Macrophage depletion in inflamed rat knees prevents the activation of synovial mesenchymal stem cells by weakening Nampt and Spp1 signaling	134
Multi-omics approach to precision medicine for immune-mediated diseases	98
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery	79
Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration	62
Peripheral and central regulation of neuro–immune crosstalk	60
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	51
Cross-talk between nervous, immune, and metabolic systems	48
Correction: Autoinflammatory disease: clinical perspectives and therapeutic strategies	46
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization	43
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	42
Umbilical cord blood and cord tissue banking as somatic stem cell resources to support medical cell modalities	35
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	35
Immune cell trafficking: a novel perspective on the gut-skin axis	33
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	33
In vivo imaging of inflammatory response in cancer research	32
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	31
Molecular biology of autoinflammatory diseases	31
Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2	31
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	30
IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury	29
Rapid and high-purity differentiation of human medium spiny neurons reveals LMNB1 hypofunction and subtype necessity in modeling Huntington’s disease	28
Par2-mediated responses in inflammation and regeneration: choosing between repair and damage	26
Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury	26
Innate immune recognition against SARS-CoV-2	25
Role of the Hippo pathway in liver regeneration and repair: recent advances	25

Autoinflammatory disease: clinical perspectives and therapeutic strategies	25
A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis	24
Accelerating corneal wound healing using exosome-mediated targeting of NF-κB c-Rel	23
Adipose-derived mesenchymal stem cell therapy for connective tissue diseases and complications	23
Pathophysiological functions of semaphorins in the sympathetic nervous system	23
Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion	23
A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1	22
Destruction and regeneration in bone and cartilage	22
Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications	22
A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation	21
Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis	21
Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy	20
Characterization of the human gut virome in metabolic and autoimmune diseases	20
Transition of clinical and basic studies on liver cirrhosis treatment using cells to seek the best treatment	19
From bench to bedside: the role of gastrointestinal stem cells in health and disease	19
Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus	19
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice	19
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	19
Intravital imaging of immune responses in intestinal inflammation	18
Hippo pathway in cell–cell communication: emerging roles in development and regeneration	17
A disease-specific iPS cell resource for studying rare and intractable diseases	17
A review of current status of cell-based therapies for aortic aneurysms	16
Editorial: Towards a better understanding of the physiology of the lymphatics	16
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	15
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	15
A novel prostaglandin I2 agonist, ONO-1301, attenuates liver inflammation and suppresses fibrosis in non-alcoholic steatohepatitis model mice	15
Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model	15
NRP2+ human mesenchymal stem cells have stemness-associated properties	15
The role of lymphatics in intestinal inflammation	15
Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease—a multi-faceted approach to fever of unknown origin of childhood	15
Cardiac regeneration by direct reprogramming in this decade and beyond	15