OOIR: Observatory of International Research

Papers

(The TQCC of Inflammation and Regeneration is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
Macrophage depletion in inflamed rat knees prevents the activation of synovial mesenchymal stem cells by weakening Nampt and Spp1 signaling	140
Jdp2 is a spatiotemporal transcriptional activator of the AhR via the Nrf2 gene battery	103
Beyond the bulk: overview and novel insights into the dynamics of muscle satellite cells during muscle regeneration	84
Multi-omics approach to precision medicine for immune-mediated diseases	63
Peripheral and central regulation of neuro–immune crosstalk	60
Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells	52
Cross-talk between nervous, immune, and metabolic systems	49
Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome	49
Correction: Autoinflammatory disease: clinical perspectives and therapeutic strategies	46
Organization of self-advantageous niche by neural stem/progenitor cells during development via autocrine VEGF-A under hypoxia	37
Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis	36
Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization	35
Umbilical cord blood and cord tissue banking as somatic stem cell resources to support medical cell modalities	35
Extracellular vesicles from immortalized mesenchymal stromal cells protect against neonatal hypoxic-ischemic brain injury	34
Immune cell trafficking: a novel perspective on the gut-skin axis	33
In vivo imaging of inflammatory response in cancer research	32
Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury	31
Rapid and high-purity differentiation of human medium spiny neurons reveals LMNB1 hypofunction and subtype necessity in modeling Huntington’s disease	31
Molecular biology of autoinflammatory diseases	30
Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation	29
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases—RA as a role model	28
IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury	28
Promotion of axon regeneration and protection on injured retinal ganglion cells by rCXCL2	27
A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis	26
Autoinflammatory disease: clinical perspectives and therapeutic strategies	26

Pathophysiological functions of semaphorins in the sympathetic nervous system	25
Role of the Hippo pathway in liver regeneration and repair: recent advances	25
Accelerating corneal wound healing using exosome-mediated targeting of NF-κB c-Rel	25
Adipose-derived mesenchymal stem cell therapy for connective tissue diseases and complications	24
Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion	24
Par2-mediated responses in inflammation and regeneration: choosing between repair and damage	24
Destruction and regeneration in bone and cartilage	23
Innate immune recognition against SARS-CoV-2	23
A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1	23
Stem cell-based drug delivery strategy for skin regeneration and wound healing: potential clinical applications	20
Epigenetic targets of Janus kinase inhibitors are linked to genetic risks of rheumatoid arthritis	20
A case of refractory systemic lupus erythematosus with monocytosis exhibiting somatic KRAS mutation	20
From bench to bedside: the role of gastrointestinal stem cells in health and disease	19
Genome editing iPSC to purposing enhancement of induce CD8 killer T cell function for regenerative immunotherapy	19
Characterization of the human gut virome in metabolic and autoimmune diseases	19
Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia	19
Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus	19
Hippo pathway in cell–cell communication: emerging roles in development and regeneration	18
Transition of clinical and basic studies on liver cirrhosis treatment using cells to seek the best treatment	18
Intravital imaging of immune responses in intestinal inflammation	17
A review of current status of cell-based therapies for aortic aneurysms	16
A disease-specific iPS cell resource for studying rare and intractable diseases	16
Innate immune memory in macrophage differentiation and cardiovascular diseases	16
Th22 is the effector cell of thymosin β15-induced hair regeneration in mice	16
Clinical perspectives and therapeutic strategies: pediatric autoinflammatory disease—a multi-faceted approach to fever of unknown origin of childhood	15
Human PBMC-based humanized mice exhibit myositis features and serve as a drug evaluation model	15
Cancer ego-system in glioma: an iron-replenishing niche network systemically self-organized by cancer stem cells	15
Editorial: Towards a better understanding of the physiology of the lymphatics	15
The role of lymphatics in intestinal inflammation	14
NRP2+ human mesenchymal stem cells have stemness-associated properties	14
Research hotspots and trends for axon regeneration (2000–2021): a bibliometric study and systematic review	14