Bioscience Trends

Papers
(The median citation count of Bioscience Trends is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Poor emotional status increases the risk of attempted suicide for the elderly age 55 and older in Shanghai, China: A longitudinal follow-up study209
Development and validation of a machine-learning model to predict lymph node metastasis of intrahepatic cholangiocarcinoma: A retrospective cohort study133
Heparin therapy in COVID-19: Call for randomized controlled trials (RCTs)110
Effect of transcatheter arterial chemoembolization combined with lenvatinib plus anti–PD-1 antibodies in patients with unresectable hepatocellular carcinoma: A treatment with Chinese characteristics109
Corrigendum to "Shufengjiedu capsules protect against neuronal loss in olfactory epithelium and lung injury by enhancing autophagy in rats with allergic rhinitis", BioScience Trends. 2019; 13(6):530-584
New progress in elucidating the relationship between cancer therapy and cardiovascular toxicity67
Value of multidisciplinary team (MDT) in minimally invasive treatment of complex intrahepatic bile duct stones67
Effects and mechanisms of microenvironmental acidosis on osteoclast biology51
Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction49
Revealing the enhancement effect of social capital on the individual performance of core members in elderly caring organizations: A study from Anhui, China46
Rapid evolution of the COVID-19 pandemic calls for a unified public health response34
Treatment of biliary tract carcinoma over the last 30 years30
An innovative two-wing model for balancing the demands of inpatients with COVID-19 and general medical service in a designated hospital for COVID-19 in Shenzhen, China26
The initiation, exploration, and development of hospital-based health technology assessment in China: 2005 ‒ 202226
Interaction with ERp57 is required for progranulin protection against Type 2 Gaucher disease25
Formulation and interpretation of the Chinese Guidelines for Surgical Treatment of Obesity and Type 2 Diabetes Mellitus24
Focusing on development of novel sampling approaches and alternative therapies for COVID-19: Are they still useful in an era after the pandemic?21
EMG-FRNet: A feature reconstruction network for EMG irrelevant gesture recognition20
Feasibility of novel intraoperative navigation for anatomical liver resection using real-time virtual sonography combined with indocyanine green fluorescent imaging technology19
New challenges to fighting COVID-19: Virus variants, potential vaccines, and development of antivirals18
Management of non-alcoholic fatty liver disease-associated hepatocellular carcinoma18
Association of the national level of human development with the incidence and mortality of congenital birth defects in 2019: A cross-sectional study from 189 countries17
Changes in and challenges regarding the surgical treatment of hepatocellular carcinoma in China17
Potential value and advances in research on bone mineral density (BMD) measurement in the auxiliary clinical assessment of hepatocellular carcinoma15
The role of cholesterol-modified prognostic nutritional index in nutritional status assessment and predicting survival after liver resection for hepatocellular carcinoma15
Liquid-liquid phase separation: A new perspective to understanding aging and pathogenesis14
Serum proteomics reveals early biomarkers of Alzheimer's disease: The dual role of <i>APOE-ε4 </i>13
Multimodal optimal matching and augmentation method for small sample gesture recognition13
Post-stroke dysphagia: Neurological regulation and recovery strategies13
Clinical guidelines for the diagnosis and treatment of HIV/AIDS in China: Their potential benefits and impact on public health12
Advances in deep learning: From diagnosis to treatment12
Infectious disease activity during the COVID-19 epidemic in Japan: Lessons learned from prevention and control measures12
Treating patients infected with the SARS-CoV-2 Omicron variant with a traditional Chinese medicine, Shufeng Jiedu capsule12
Using a multidisciplinary team for the staged management and optimally minimally invasive treatment of severe acute pancreatitis11
The management of dementia worldwide: A review on policy practices, clinical guidelines, end-of-life care, and challenge along with aging population11
RNA-binding proteins in metabolic-associated fatty liver disease (MAFLD): From mechanism to therapy11
The ability of Segmenting Anything Model (SAM) to segment ultrasound images11
Influence of intermittent fasting on autophagy in the liver11
The multidisciplinary management of hepatocellular carcinoma with portal vein tumor thrombus10
Simulation of SARS-CoV-2 epidemic trends in Tokyo considering vaccinations, virus mutations, government policies and PCR tests10
Dysfunction of peripheral regulatory T cells predicts lung injury after cardiopulmonary bypass10
Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma <i>via</i> the miRNA-4474-3P-ALOX-15 and EMT axes10
Macroscopically complete excision is a beneficial strategy for selected patients with peritoneal sarcomatosis10
Elderly patients with comorbid hypertension who prefer primary care have a lower rate of polypharmacy: A cross-sectional study in Shanghai, China10
Notch signaling pathway plays a critical role in chemotherapeutic drug-induced vestibular injury10
Growth and differentiation factor 15: An emerging therapeutic target for brain diseases8
Bacteriophage therapy for empyema caused by carbapenem-resistant <i>Pseudomonas aeruginosa </i>8
Revealing the gut microbiome mystery: A meta-analysis revealing differences between individuals with autism spectrum disorder and neurotypical children8
COVID-19 vaccine research focusses on safety, efficacy, immunoinformatics, and vaccine production and delivery: a bibliometric analysis based on VOSviewer8
How spousal cognitive functioning affects the level of depression in middle-aged and older adults: An instrumental variable study based on CHARLS in China8
The immune response of hepatocellular carcinoma after locoregional and systemic therapies: The available combination option for immunotherapy8
What does oral care mean to society?8
Call for special attention to the caregiver burden of patients with drug-resistant tuberculosis in low- and middle-income countries8
Update: Drug treatment options for coronavirus disease 2019 (COVID-19)8
Can nasal irrigation with chlorine dioxide be considered as a potential alternative therapy for respiratory infectious diseases? The example of COVID-197
Time to onset of drug-induced parkinsonism: Analysis using a large Japanese adverse event self-reporting database7
Neurosurgical perioperative management of frail elderly patients7
Neoadjuvant therapy <i>vs</i>. upfront surgery for resectable pancreatic cancer: An update on a systematic review and meta-analysis7
ChIP-sequencing analysis of E2F transcription factor 2 reveals its role in various biological processes of rheumatoid arthritis synovial fibroblasts7
Impact of sarcopenia on S1 adjuvant chemotherapy and prognosis in pancreatic cancer patients7
Association of MTHFR 677C>T polymorphism with pregnancy outcomes in IVF/ICSI-ET recipients with adequate synthetic folic acid supplementation7
Elevation of circulating DNAs of disease-associated cytokines in serum cell-free DNA from patients with alopecia areata7
Expert consensus on sequential surgery after immune-targeted conversion therapy for advanced hepatocellular carcinoma in China6
Trends in the treatment of advanced pancreatic cancer6
Suppression of STK39 weakens the MASLD/MASH process by protecting the intestinal barrier6
The effect of the female genital tract and gut microbiome on reproductive dysfunction6
What is always necessary throughout efforts to prevent and control COVID-19 and other infectious diseases? A physical containment strategy and public mobilization and management6
A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan6
Machine learning-based prognostic prediction and surgical guidance for intrahepatic cholangiocarcinoma6
How do RNA binding proteins trigger liquid-liquid phase separation in human health and diseases?6
The role of influenza in the era of COVID-19: Can we forget it?6
Recent trends and new developments in liver transplantation6
More effective vaccines and oral antivirals: Keys for the battle against Omicron6
Conversion therapy for initially unresectable hepatocellular carcinoma: Current status and prospects6
The latest policies, practices, and hotspots in research in conjunction with the aging of Japan's population6
Role of a multidisciplinary team (MDT) in the diagnosis, treatment, and outcomes of inflammatory bowel disease: a single Chinese center's experience6
Integration of wearable devices and deep learning: New possibilities for health management and disease prevention6
Characteristics, scope of activity, and negative emotions in elderly women with urinary incontinence: Based on a longitudinal follow-up in Shanghai, China6
Update on hormone therapy for the management of postmenopausal women6
Rapid SARS-CoV-2 antigen detection potentiates early diagnosis of COVID-19 disease6
Detecting latent tuberculosis infection with a breath test using mass spectrometer: A pilot cross-sectional study5
A well-matched marriage of immunotherapy and radiofrequency ablation to reduce the relapse and progression of hepatocellular carcinoma5
Exploring the multiple therapeutic mechanisms and challenges of mesenchymal stem cell-derived exosomes in Alzheimer's disease5
Optimized concurrent hearing and genetic screening in Beijing, China: A cross-sectional study5
Association between abnormal lipid metabolism and Alzheimer's disease: New research has revealed significant findings on the APOE4 genotype in microglia5
The E2F transcription factor 2: What do we know?5
Unmasking the silent killer: The hidden aggressiveness of signet-ring cell carcinoma in gallbladder cancer5
Conversion therapy and maintenance therapy for primary hepatocellular carcinoma5
Current status of and challenges posed by autism spectrum disorders in China: Prevalence, legal issues, and public awareness5
SEC24C suppresses the propagation and chemoresistance of hepatocellular carcinoma by promoting unfolded protein response-related apoptosis5
Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance4
Cytomegalovirus viremia is associated with poor outcomes in AIDS patients with disseminated nontuberculous mycobacterial disease4
Breast cancer and pregnancy: Why special considerations prior to treatment are needed in multidisciplinary care4
Association of angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists use with risk of atrial fibrillation after pacemaker implantation among very old patients4
Anti-neuroinflammatory activity of Shenqi Fuzheng Injection and its main active constituents4
Herbal medicines exhibit a high affinity for ACE2 in treating COVID-194
Automated machine learning-based model for the prediction of pedicle screw loosening after degenerative lumbar fusion surgery4
Donor-recipient matching in adult liver transplantation: Current status and advances4
How should designated COVID-19 hospitals in megacities implement a precise management strategy in response to Omicron?4
Impact of China's COVID-19 prevention and control efforts on outbreaks of influenza4
Pal power: Demonstration of the functional association of the <i>Helicobacter pylori</i> flagellar motor with peptidoglycan-associated lipoprotein (Pal) and its preliminary crystallographi4
Development of an <i>in vitro</i> insulin resistance dissociated model of hepatic steatosis by co-culture system4
A brief summary regarding the roles of interleukin-11 in neurological diseases4
New possibilities for medical support systems utilizing artificial intelligence (AI) and data platforms3
Contemporary oral anticoagulant therapy of patients with atrial fibrillation in China: Status, obstacles, and strategies for improvement3
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information3
Association between sarcopenia with incident cardio-cerebrovascular disease: A systematic review and meta-analysis3
Soluble β-amyloid impaired the GABA inhibition by mediating KCC2 in early APP/PS1 mice3
Diabetes mellitus, glycemic traits, SGLT2 inhibition, and risk of pulmonary arterial hypertension: A Mendelian randomization study3
Timing of parathyroidectomy for kidney transplant patients with secondary hyperparathyroidism: A practical overview3
Strengthening medical facility responses to respiratory infectious diseases: Global trends, challenges, and innovations post-COVID-193
Advances in systemic therapy leading to conversion surgery for advanced hepatocellular carcinoma3
NAD(P)H-quinone oxidoreductase 1 induces complicated effects on mitochondrial dysfunction and ferroptosis in an expression level-dependent manner3
Comparison of diagnosis-related groups (DRG)-based hospital payment system design and implementation strategies in different countries: The case of ischemic stroke3
The status of surrogacy in China3
Blocking progression from intervenable mild cognitive impairment to irreversible dementia, what can we do?3
The prognostic nutritional index and tumor pathological characteristics predict the prognosis of elderly patients with early-stage hepatocellular carcinoma after surgery3
Burnout in nurses during the COVID-19 pandemic in China: New challenges for public health3
Community-acquired pneumonia: Trends in and research on drug resistance and advances in new antibiotics2
Evaluation of the value of <i>Synechococcus</i> 7942 as a sensitizer for photo-sonodynamic therapy against breast cancer2
Liver transplantation for patients with hepatocellular carcinoma: Its current status and advances2
Plasma extracellular vesicle pathognomonic proteins as the biomarkers of the progression of Parkinson's disease2
From SARS to the Omicron variant of COVID-19: China's policy adjustments and changes to prevent and control infectious diseases2
Monoclonal antibody therapy for Alzheimer's disease focusing on intracerebral targets2
Roadmap for ending TB in China by 2035: The challenges and strategies2
Genetic features of TP53 mutation and its downstream FOXA1 in prostate cancer2
An overview: Management of patients with advanced hepatocellular carcinoma2
Marburg virus disease: A deadly rare virus is coming2
<i>N<sup>5</sup></i>-((perfluorophenyl)amino)glutamine regulates BACE1, tau phosphorylation, synaptic function, and neuroinflammation in Alzheimer's disease models2
Sequelae of long COVID, known and unknown: A review of updated information2
Elevated serum CA19-9 indicates severe liver inflammation and worse survival after curative resection in hepatitis B-related hepatocellular carcinoma2
Comprehensive assessment and treatment strategies for dysphagia in the elderly population: Current status and prospects2
Corrigendum to "Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma via the miRNA-4474-3P-ALOX-15 and EMT axes", BioScience Trends. 2022; 16(4):267-2812
An expanded view of infertility: The challenge of the changing profiling of major birth defects in China2
Unveiling the unexplored secret: Aggressive behavior and poor survival in intrahepatic mucinous adenocarcinoma compared to conventional adenocarcinoma2
Thrombin cleaves recombinant soluble thrombomodulin into a lectin-like domain fragment and a fragment with protein C-activating cofactor activity2
From light to insight: Functional near-infrared spectroscopy for unravelling cognitive impairment during task performance2
The glamor of and insights regarding hydrotherapy, from simple immersion to advanced computer-assisted exercises: A narrative review2
Development of a novel cholesterol tag-based system for trans-membrane transport of protein drugs2
Analysis of microsatellite instability using Promega panel in dermatofibrosarcoma protuberans2
Emerging infectious diseases never end: The fight continues2
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