OOIR: Observatory of International Research

Papers

(The TQCC of Bioscience Trends is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Poor emotional status increases the risk of attempted suicide for the elderly age 55 and older in Shanghai, China: A longitudinal follow-up study	209
Development and validation of a machine-learning model to predict lymph node metastasis of intrahepatic cholangiocarcinoma: A retrospective cohort study	133
Heparin therapy in COVID-19: Call for randomized controlled trials (RCTs)	110
Effect of transcatheter arterial chemoembolization combined with lenvatinib plus anti–PD-1 antibodies in patients with unresectable hepatocellular carcinoma: A treatment with Chinese characteristics	109
Corrigendum to "Shufengjiedu capsules protect against neuronal loss in olfactory epithelium and lung injury by enhancing autophagy in rats with allergic rhinitis", BioScience Trends. 2019; 13(6):530-5	84
Value of multidisciplinary team (MDT) in minimally invasive treatment of complex intrahepatic bile duct stones	67
New progress in elucidating the relationship between cancer therapy and cardiovascular toxicity	67
Effects and mechanisms of microenvironmental acidosis on osteoclast biology	51
Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction	49
Revealing the enhancement effect of social capital on the individual performance of core members in elderly caring organizations: A study from Anhui, China	46
Rapid evolution of the COVID-19 pandemic calls for a unified public health response	34
Treatment of biliary tract carcinoma over the last 30 years	30
The initiation, exploration, and development of hospital-based health technology assessment in China: 2005 ‒ 2022	26
An innovative two-wing model for balancing the demands of inpatients with COVID-19 and general medical service in a designated hospital for COVID-19 in Shenzhen, China	26
Interaction with ERp57 is required for progranulin protection against Type 2 Gaucher disease	25
Formulation and interpretation of the Chinese Guidelines for Surgical Treatment of Obesity and Type 2 Diabetes Mellitus	24
Focusing on development of novel sampling approaches and alternative therapies for COVID-19: Are they still useful in an era after the pandemic?	21
EMG-FRNet: A feature reconstruction network for EMG irrelevant gesture recognition	20
Feasibility of novel intraoperative navigation for anatomical liver resection using real-time virtual sonography combined with indocyanine green fluorescent imaging technology	19
New challenges to fighting COVID-19: Virus variants, potential vaccines, and development of antivirals	18
Management of non-alcoholic fatty liver disease-associated hepatocellular carcinoma	18
Changes in and challenges regarding the surgical treatment of hepatocellular carcinoma in China	17
Association of the national level of human development with the incidence and mortality of congenital birth defects in 2019: A cross-sectional study from 189 countries	17
The role of cholesterol-modified prognostic nutritional index in nutritional status assessment and predicting survival after liver resection for hepatocellular carcinoma	15
Potential value and advances in research on bone mineral density (BMD) measurement in the auxiliary clinical assessment of hepatocellular carcinoma	15

Liquid-liquid phase separation: A new perspective to understanding aging and pathogenesis	14
Serum proteomics reveals early biomarkers of Alzheimer's disease: The dual role of <i>APOE-ε4 </i>	13
Multimodal optimal matching and augmentation method for small sample gesture recognition	13
Post-stroke dysphagia: Neurological regulation and recovery strategies	13
Infectious disease activity during the COVID-19 epidemic in Japan: Lessons learned from prevention and control measures	12
Treating patients infected with the SARS-CoV-2 Omicron variant with a traditional Chinese medicine, Shufeng Jiedu capsule	12
Clinical guidelines for the diagnosis and treatment of HIV/AIDS in China: Their potential benefits and impact on public health	12
Advances in deep learning: From diagnosis to treatment	12
Influence of intermittent fasting on autophagy in the liver	11
Using a multidisciplinary team for the staged management and optimally minimally invasive treatment of severe acute pancreatitis	11
The management of dementia worldwide: A review on policy practices, clinical guidelines, end-of-life care, and challenge along with aging population	11
RNA-binding proteins in metabolic-associated fatty liver disease (MAFLD): From mechanism to therapy	11
The ability of Segmenting Anything Model (SAM) to segment ultrasound images	11
Macroscopically complete excision is a beneficial strategy for selected patients with peritoneal sarcomatosis	10
Elderly patients with comorbid hypertension who prefer primary care have a lower rate of polypharmacy: A cross-sectional study in Shanghai, China	10
Notch signaling pathway plays a critical role in chemotherapeutic drug-induced vestibular injury	10
The multidisciplinary management of hepatocellular carcinoma with portal vein tumor thrombus	10
Simulation of SARS-CoV-2 epidemic trends in Tokyo considering vaccinations, virus mutations, government policies and PCR tests	10
Dysfunction of peripheral regulatory T cells predicts lung injury after cardiopulmonary bypass	10
Hepatic stellate cell exosome-derived circWDR25 promotes the progression of hepatocellular carcinoma <i>via</i> the miRNA-4474-3P-ALOX-15 and EMT axes	10
What does oral care mean to society?	8
Call for special attention to the caregiver burden of patients with drug-resistant tuberculosis in low- and middle-income countries	8
Update: Drug treatment options for coronavirus disease 2019 (COVID-19)	8
Growth and differentiation factor 15: An emerging therapeutic target for brain diseases	8
Bacteriophage therapy for empyema caused by carbapenem-resistant <i>Pseudomonas aeruginosa </i>	8
Revealing the gut microbiome mystery: A meta-analysis revealing differences between individuals with autism spectrum disorder and neurotypical children	8
COVID-19 vaccine research focusses on safety, efficacy, immunoinformatics, and vaccine production and delivery: a bibliometric analysis based on VOSviewer	8
How spousal cognitive functioning affects the level of depression in middle-aged and older adults: An instrumental variable study based on CHARLS in China	8
The immune response of hepatocellular carcinoma after locoregional and systemic therapies: The available combination option for immunotherapy	8
Association of MTHFR 677C>T polymorphism with pregnancy outcomes in IVF/ICSI-ET recipients with adequate synthetic folic acid supplementation	7
Elevation of circulating DNAs of disease-associated cytokines in serum cell-free DNA from patients with alopecia areata	7
Can nasal irrigation with chlorine dioxide be considered as a potential alternative therapy for respiratory infectious diseases? The example of COVID-19	7
Time to onset of drug-induced parkinsonism: Analysis using a large Japanese adverse event self-reporting database	7
Neurosurgical perioperative management of frail elderly patients	7
Neoadjuvant therapy <i>vs</i>. upfront surgery for resectable pancreatic cancer: An update on a systematic review and meta-analysis	7
ChIP-sequencing analysis of E2F transcription factor 2 reveals its role in various biological processes of rheumatoid arthritis synovial fibroblasts	7
Impact of sarcopenia on S1 adjuvant chemotherapy and prognosis in pancreatic cancer patients	7