Cell Host & Microbe

Article	Citations
Breathe and bloom: Gut hypoxia limits C. albicans growth	576
Selenium nanoboosting of plant-beneficial microbiome	323
Waste as an antibacterial weapon	287
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation	278
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	257
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	235
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	227
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	210
Sowing the seeds of infection	199
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	198
Microbial genome mining expedition unearths trove of antiviral defenses	190
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	189
Candidalysin: An unlikely aide for fungal gut commensalism	187
When predators meet the matrix: Natural resistance via amyloid fibers	185
Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri	169
Epithelial hypoxia maintains colonization resistance against Candida albicans	163
Combatting superbugs using the evolutionary record of microbial warfare	157
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	155
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	152
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	152
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	150
MFSD6 is an entry receptor for respiratory enterovirus D68	146
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	145
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	143
There and back again: Discovering antiviral and antiphage defenses using deep homology	141

Cad1 turns ATP into phage poison	140
Antibiotic treatment ignites a fire that lasts	138
How hosts accurately command bacteria for gut health	137
Tactical terminase: How a Salmonella prophage navigates oxidative stress	137
Beta-carbolines suppress vaginal inflammation	136
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	136
A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants	127
Immunity to fungi and vaccine considerations	125
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	124
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	123
Select symbionts drive high IgA levels in the mouse intestine	113
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	113
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	112
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	111
Help from commensals: β-hex to regulate gut immunity	108
From top to bottom: Staphylococci in atopic dermatitis	108
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	107
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	105
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	105
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	104
Uniting against enteric invaders: IgA meets its microbial ally	104
Predator-prey interplay: When chemical conversation turns deadly	102
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	102
Antibiotics fire up inflammation to cool vaccine responsiveness	101
Lost and found: Reconstituting PRR immune function through co-receptor transfer	101
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	100
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	99
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	99
A lung pathobiont story: Thinking outside the Koch’s postulate box	99
Overcoming drug resistance, the natural way	95
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	94
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	94
“AHR-ming” host defense against cryptosporidiosis	93
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	93
Gut IgA: Never fear, the super inducers are here	93
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	93
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	92
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	92
Dietary environmental factors shape the immune defense against Cryptosporidium infection	91
Location matters in RSV protection	91
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	90
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	90
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	89
Decline in nitrosative stress drives antibiotic persister regrowth during infection	89
A single-cell liver atlas of Plasmodium vivax infection	87
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	87
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	84
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	84
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	84
GOSpel for tiny allies	83

AI in microbiome research: Where have we been, where are we going?	82
Methylglyoxal is an antibacterial effector produced by macrophages during infection	82
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system	82
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	81
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	80
When NOD ligands become antidotes	79
A counterintuitive antibody cocktail disrupts coxsackievirus	79
Multi-arming ourselves against drug-resistant bacteria	78
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	77
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	76
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	75
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	75
Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication	75
The gut microbiome molecular complex in human health and disease	74
On track to tackle dengue: History and future of NS4B ligands	74
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	73
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	72
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	72
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	72
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	71
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	71
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	70
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	70
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	69
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	69
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	68
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	68
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	68
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	67
Cutibacterium acnes evolution: One pore at a time	66
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	66
“Indole-gence” for the mind	65
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	65
Unclouding Clostridiodes difficile virulence with systems biology	65
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	64
Gut microbiome development and childhood undernutrition	64
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	63
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	63
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	63
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile	62
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria	61
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	61
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	60
All systems go: CRISPR crosstalk for enhanced immunity	60
Commensal microbe regulation of skin cells in disease	60
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	59
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	59
Rethinking healthy eating in light of the gut microbiome	58
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	58
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	57
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	56
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	56
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	56
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	56
Microbial Cgr2 will let your Th17 cells ROR(γT)	55
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	55
Gut bacteria help the brain with an oil change	54
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	54
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	54
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	54
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	53
Growing up: A NOD2 our microbes	53
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	53
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	53
A. baumannii’s nutrient tug-of-war	51
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	51
Linking E. coli to fibrosis in Crohn’s disease	51
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	51
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	51
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	50
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	50
Going viral: The role of mobile genetic elements in bacterial immunity	49
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	49
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	48
Walking down the phosphorylation path to root immunity	48
An expanded arsenal of immune systems that protect bacteria from phages	48
MAMPs: A devil tamed becomes an angel	48
Even old foes can learn sweet new tricks	48
Viral mimicry protects from infection when you’re expecting	48
The gut-brain axis goes viral	48

Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	47
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	47
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts	46
Multi-armed antibiotics for Gram-positive bacteria	46
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	46
Deep learning helps fight against antibiotic resistance	46
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	46
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	46
Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor	45
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	45
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly	45
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	45
Mimicry games: NPC-like MX2 condensates trap viruses	45
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	44
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	44
Stoking inflammasome fires in the COVID-19 neighborhood	44
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	44
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	44
The developing infant gut microbiome: A strain-level view	43
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	43
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	43
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	43
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	42
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	42
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	42
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	42
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	41
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	40
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	40
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	40
Mg and the microbiome: A liver-protective duo	39
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	39
BCG: From veins to correlates	39
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	39
Gut microbiota and metabolites drive chronic sickle cell disease pain in mice	39
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	38
Bioengineered gut bacterium synthesizing levodopa alleviates motor deficits in models of Parkinson’s disease	38
Oh, how we have grown!	38
Stitching together a healthy gut microbiome with fiber	38
RTS,S today and tomorrow’s science	38
Compensating P. falciparum artemisinin resistance	37
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	37
Bacterial molecular syringe for drug delivery	37
It takes a plant village to raise a microbiome	37
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	37
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	35
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	35
The HY5-NPR1 module governs light-dependent virulence of a plant bacterial pathogen	35
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	35
Designing boosting immunogens for HIV-1 vaccine development	35
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	35
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	34
Charting a phage genome atlas	34
RNA editing of genomic neighbors controls antiviral response in fungi	34
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	34
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	34
Fishing for obesity-related gut microbiome enterotype	34
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	33
Networks of the symbiosis-immunity continuum in plants	33
Gut microbiome and necrotizing enterocolitis: Understanding the connection to find a cure	33
Inter-kingdom lipid messengers sustain gut harmony	33
Mechanisms of bacterial immunity, protection, and survival during interbacterial warfare	33
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	33
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	32
Bacterial defense systems exhibit synergistic anti-phage activity	32
A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme	32
Bug in the code: TB blocks DNA repair	31
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut	31
Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies	31
Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis	31
Human gut bacterial metabolism drives Th17 activation and colitis	31
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids	31
Restoration of the human skin microbiome following immune recovery after hematopoietic stem cell transplantation	30
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps	30
Unbiased discovery of natural sequence variants that influence fungal virulence	30
A tough act to swallow: Streptococcus anginosus and gastric cancer	30
Lactobacillus reuteri joins the liver autoimmune arena	29
Sugar transporters spatially organize microbiota colonization along the longitudinal root axis of Arabidopsis	29
Stress less: Viral mastery of the RNA G-quadruplex	29
Paneth cell TNF signaling induces gut bacterial translocation and sepsis	29
Neutrophil recruitment during intestinal inflammation primes Salmonella elimination by commensal E. coli in a context-dependent manner	28
Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2	27
Taking the pulse: Bacterial responses to intermittent antibiotics	27
Prospects for preventing cancer with anti-microbial prophylactic vaccines	26
Microbiomes in Neverland	26
Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements	26
Vivax malaria and Duffy antigen: Stop being so negative	26
SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns	26
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals	25
Here, we grow	25
Meta-organismal metabolism in cardiovascular disease	25
Plant cell-cycle regulators control the nuclear environment for viral pathogenesis	25
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin	25
Arresting microbiome development limits immune system maturation and resistance to infection in mice	25
Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice	25