Cell Host & Microbe

Article	Citations
Sowing the seeds of infection	516
Microbial genome mining expedition unearths trove of antiviral defenses	288
Selenium nanoboosting of plant-beneficial microbiome	253
Candidalysin: An unlikely aide for fungal gut commensalism	230
Breathe and bloom: Gut hypoxia limits C. albicans growth	226
Waste as an antibacterial weapon	206
Combatting superbugs using the evolutionary record of microbial warfare	203
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	198
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	196
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	182
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	179
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	179
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	175
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	167
MFSD6 is an entry receptor for respiratory enterovirus D68	165
Epithelial hypoxia maintains colonization resistance against Candida albicans	164
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	161
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	158
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	149
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	148
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	147
Cad1 turns ATP into phage poison	143
Help from commensals: β-hex to regulate gut immunity	139
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	137
Immunity to fungi and vaccine considerations	136

Select symbionts drive high IgA levels in the mouse intestine	133
Beta-carbolines suppress vaginal inflammation	132
There and back again: Discovering antiviral and antiphage defenses using deep homology	132
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	130
Tactical terminase: How a Salmonella prophage navigates oxidative stress	129
Uniting against enteric invaders: IgA meets its microbial ally	129
How hosts accurately command bacteria for gut health	126
Antibiotic treatment ignites a fire that lasts	126
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	125
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	124
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	120
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	119
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	117
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	115
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	112
From top to bottom: Staphylococci in atopic dermatitis	111
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	105
Overcoming drug resistance, the natural way	104
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	103
Dietary environmental factors shape the immune defense against Cryptosporidium infection	102
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	101
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	101
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7	100
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	99
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism	98
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	97
Decline in nitrosative stress drives antibiotic persister regrowth during infection	94
Location matters in RSV protection	93
A lung pathobiont story: Thinking outside the Koch’s postulate box	92
“AHR-ming” host defense against cryptosporidiosis	92
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	92
Gut IgA: Never fear, the super inducers are here	91
Antibiotics fire up inflammation to cool vaccine responsiveness	90
Predator-prey interplay: When chemical conversation turns deadly	90
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	90
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	89
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	88
A single-cell liver atlas of Plasmodium vivax infection	88
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	87
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	87
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	87
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection	87
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	87
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	86
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	86
Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis	86
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	84
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	82
A counterintuitive antibody cocktail disrupts coxsackievirus	82
Goodbye PAM: Phage λ’s Red recombination system cripples PAMs and helps dodge CRISPR attacks	82

When NOD ligands become antidotes	81
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	79
On track to tackle dengue: History and future of NS4B ligands	78
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	77
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	77
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer	77
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	76
Multi-arming ourselves against drug-resistant bacteria	76
Brain development in premature infants: A bug in the programming system?	76
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	75
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	73
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	71
GOSpel for tiny allies	71
Methylglyoxal is an antibacterial effector produced by macrophages during infection	70
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	69
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	69
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	69
The gut microbiome molecular complex in human health and disease	68
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	67
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	67
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	67
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	67
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	66
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	66
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	65
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	65
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	65
AI in microbiome research: Where have we been, where are we going?	64
Cutibacterium acnes evolution: One pore at a time	63
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	63
Commensal microbe regulation of skin cells in disease	63
Unclouding Clostridiodes difficile virulence with systems biology	63
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	63
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	62
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	62
“Indole-gence” for the mind	61
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile	60
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	59
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	59
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	58
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	58
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis	57
Gut microbiome development and childhood undernutrition	57
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	57
Rethinking healthy eating in light of the gut microbiome	57
Microbial Cgr2 will let your Th17 cells ROR(γT)	56
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	56
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	56
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	55
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	54
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	54
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	54
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	54
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	54
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	53
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	53
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	52
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	52
The gut-brain axis goes viral	51
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	51
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	51
Even old foes can learn sweet new tricks	51
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	51
Linking E. coli to fibrosis in Crohn’s disease	50
MAMPs: A devil tamed becomes an angel	50
Growing up: A NOD2 our microbes	50
Viral mimicry protects from infection when you’re expecting	49
Walking down the phosphorylation path to root immunity	49
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	49
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	48
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	48
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	48
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	47
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	47
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	47
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	46
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	46
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	45
Going viral: The role of mobile genetic elements in bacterial immunity	45
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	45

Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	45
Multi-armed antibiotics for Gram-positive bacteria	45
An expanded arsenal of immune systems that protect bacteria from phages	44
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	44
A colon cancer “prequel”	44
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	44
Stoking inflammasome fires in the COVID-19 neighborhood	43
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	43
License to LAP	43
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	43
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization	43
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	42
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	42
Mimicry games: NPC-like MX2 condensates trap viruses	42
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	42
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	42
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	42
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	41
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	41
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	41
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	41
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	41
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	41
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	41
Compensating P. falciparum artemisinin resistance	40
The developing infant gut microbiome: A strain-level view	40
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	39
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	38
It takes a plant village to raise a microbiome	38
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	38
Mg and the microbiome: A liver-protective duo	38
Bacterial molecular syringe for drug delivery	38
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	37
RTS,S today and tomorrow’s science	37
Oh, how we have grown!	37
Stitching together a healthy gut microbiome with fiber	37
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	37
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	37
BCG: From veins to correlates	36
Designing boosting immunogens for HIV-1 vaccine development	36
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	35
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	35
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	35
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	35
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	35
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	34
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	33
Fishing for obesity-related gut microbiome enterotype	33
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	33
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	33
Happy families	33
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	33
Mechanisms of bacterial immunity, protection, and survival during interbacterial warfare	32
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	32
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids	32
Gut microbiome and necrotizing enterocolitis: Understanding the connection to find a cure	32
Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis	32
A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme	31
Bacterial defense systems exhibit synergistic anti-phage activity	31
Meta-organismal metabolism in cardiovascular disease	31
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut	31
Human gut bacterial metabolism drives Th17 activation and colitis	31
Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies	31
RNA editing of genomic neighbors controls antiviral response in fungi	31
Symbiont-regulated serotonin biosynthesis modulates tick feeding activity	31
Bug in the code: TB blocks DNA repair	31
Whack-a-virus: HIV-specific T cells play an exhausting game	30
Microbiomes in Neverland	30
COVID-19 as a catalyst for vaccine manufacturing: A South African experience	30
Here, we grow	30
Taking the pulse: Bacterial responses to intermittent antibiotics	30
Stress less: Viral mastery of the RNA G-quadruplex	30
Unbiased discovery of natural sequence variants that influence fungal virulence	29
Lactobacillus reuteri joins the liver autoimmune arena	29
Prospects for preventing cancer with anti-microbial prophylactic vaccines	29
Vivax malaria and Duffy antigen: Stop being so negative	29
A tough act to swallow: Streptococcus anginosus and gastric cancer	29
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps	28
Neutrophil recruitment during intestinal inflammation primes Salmonella elimination by commensal E. coli in a context-dependent manner	28
Sugar transporters spatially organize microbiota colonization along the longitudinal root axis of Arabidopsis	28
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin	28
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals	28
Restoration of the human skin microbiome following immune recovery after hematopoietic stem cell transplantation	28
Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements	28
SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns	27
Paneth cell TNF signaling induces gut bacterial translocation and sepsis	27
Biomarker-responsive engineered probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice	27
Arresting microbiome development limits immune system maturation and resistance to infection in mice	27
Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses	27
Heritable oral microbes and their importance in microbiome research for public health	26
To sense or not to sense, Paneth cell regulation of mucosal immunity	26
Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2	26
Turning CRISPR on with antibiotics	26
Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections	25
Host-microbe circadian dynamics: Finding a rhythm and hitting a groove in scientific inquiry	25