Cell Host & Microbe

Article	Citations
Waste as an antibacterial weapon	623
Microbial genome mining expedition unearths trove of antiviral defenses	350
Sowing the seeds of infection	315
When predators meet the matrix: Natural resistance via amyloid fibers	299
Candidalysin: An unlikely aide for fungal gut commensalism	296
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	253
Selenium nanoboosting of plant-beneficial microbiome	236
Hide and seek: Cryptococcus evasion of microglial sensing enables meningitis	223
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	214
Combatting superbugs using the evolutionary record of microbial warfare	214
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	204
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	202
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	196
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation	188
Breathe and bloom: Gut hypoxia limits C. albicans growth	174
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	171
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	167
Epithelial hypoxia maintains colonization resistance against Candida albicans	155
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	155
MFSD6 is an entry receptor for respiratory enterovirus D68	154
A CLOCK-targeting lncRNA induces trained immunity against tuberculosis	152
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	151
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	151
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	149
Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri	149

There and back again: Discovering antiviral and antiphage defenses using deep homology	148
A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants	145
How hosts accurately command bacteria for gut health	145
From top to bottom: Staphylococci in atopic dermatitis	143
Uniting against enteric invaders: IgA meets its microbial ally	138
Beta-carbolines suppress vaginal inflammation	130
Immunity to fungi and vaccine considerations	130
Cad1 turns ATP into phage poison	130
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	127
Tactical terminase: How a Salmonella prophage navigates oxidative stress	126
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	119
Antibiotic treatment ignites a fire that lasts	116
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	114
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	112
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	111
Select symbionts drive high IgA levels in the mouse intestine	111
Help from commensals: β-hex to regulate gut immunity	111
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	110
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	110
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	109
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	109
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	107
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	106
Antibiotics fire up inflammation to cool vaccine responsiveness	103
A lung pathobiont story: Thinking outside the Koch’s postulate box	103
Lost and found: Reconstituting PRR immune function through co-receptor transfer	103
Overcoming drug resistance, the natural way	102
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	102
“AHR-ming” host defense against cryptosporidiosis	100
Gut IgA: Never fear, the super inducers are here	100
Predator-prey interplay: When chemical conversation turns deadly	99
Location matters in RSV protection	99
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	99
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	98
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	97
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	96
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	96
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	95
A single-cell liver atlas of Plasmodium vivax infection	95
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	94
Dietary environmental factors shape the immune defense against Cryptosporidium infection	94
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	93
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	93
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	93
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	91
Decline in nitrosative stress drives antibiotic persister regrowth during infection	90
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	87
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	87
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	87
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	86

Systems virology as a cornerstone for pandemic responsiveness: A G2P-Japan perspective	86
GOSpel for tiny allies	86
Multi-arming ourselves against drug-resistant bacteria	85
A counterintuitive antibody cocktail disrupts coxsackievirus	83
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	83
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	83
When NOD ligands become antidotes	83
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system	81
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	80
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	80
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	79
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	78
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	76
Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication	75
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	75
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	73
Restoring a gut Bifidobacterium community in early infancy	73
Methylglyoxal is an antibacterial effector produced by macrophages during infection	71
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	71
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	70
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	70
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	69
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	69
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	69
The gut microbiome molecular complex in human health and disease	69
AI in microbiome research: Where have we been, where are we going?	68
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	68
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	67
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	66
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	65
A global survey of taxa-metabolic associations across mouse microbiome communities	65
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	65
The Africa COVID-19 legacy—Improved vaccinology for pandemic preparedness	65
“Indole-gence” for the mind	64
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	63
Cutibacterium acnes evolution: One pore at a time	63
All systems go: CRISPR crosstalk for enhanced immunity	62
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria	62
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	61
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	60
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	60
Gut microbiome development and childhood undernutrition	60
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	60
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	59
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	59
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	59
Commensal microbe regulation of skin cells in disease	59
Rethinking healthy eating in light of the gut microbiome	59
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	58
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	58
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	57
Microbial Cgr2 will let your Th17 cells ROR(γT)	57
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	57
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	57
Gut bacteria help the brain with an oil change	57
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	56
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	56
Environmental and maternal imprints on infant gut metabolic development	56
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	55
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	55
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	55
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	55
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	55
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	55
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	54
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	54
Growing up: A NOD2 our microbes	54
MAMPs: A devil tamed becomes an angel	52
Walking down the phosphorylation path to root immunity	52
A. baumannii’s nutrient tug-of-war	52
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	52
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	51
Even old foes can learn sweet new tricks	51
Deep learning helps fight against antibiotic resistance	51
Linking E. coli to fibrosis in Crohn’s disease	51
The gut-brain axis goes viral	50
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	50
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	50
Going viral: The role of mobile genetic elements in bacterial immunity	50
Viral mimicry protects from infection when you’re expecting	49

Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts	49
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	49
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	48
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	48
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	48
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	48
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	48
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	47
An expanded arsenal of immune systems that protect bacteria from phages	47
Multi-armed antibiotics for Gram-positive bacteria	47
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	47
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	47
Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor	46
Stoking inflammasome fires in the COVID-19 neighborhood	46
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	46
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	46
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	45
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	45
The microbial metabolite imidazole propionate modulates hypothalamic activity and stress-induced behaviors	45
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	45
The impact of COVID-19 on children and lessons for pandemic preparedness	45
Bacteria block host cell death by protein cut-and-paste	44
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	44
Mimicry games: NPC-like MX2 condensates trap viruses	42
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	42
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	42
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	42
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly	41
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	40
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	40
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	39
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	39
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	39
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	39
The developing infant gut microbiome: A strain-level view	39
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	38
Mg and the microbiome: A liver-protective duo	38
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	38
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	37
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	37
RTS,S today and tomorrow’s science	37
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	36
Stitching together a healthy gut microbiome with fiber	36
Bioengineered gut bacterium synthesizing levodopa alleviates motor deficits in models of Parkinson’s disease	36
Oh, how we have grown!	36
The HY5-NPR1 module governs light-dependent virulence of a plant bacterial pathogen	36
It takes a plant village to raise a microbiome	35
BCG: From veins to correlates	35
Bacterial molecular syringe for drug delivery	35
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	35
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	34
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	34
Gut microbiota and metabolites drive chronic sickle cell disease pain in mice	34
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	34
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	34
Designing boosting immunogens for HIV-1 vaccine development	34
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	33
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	33
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	33
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	33
Fishing for obesity-related gut microbiome enterotype	33
Charting a phage genome atlas	33
A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme	32
Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut	32
Networks of the symbiosis-immunity continuum in plants	32
Mechanisms of bacterial immunity, protection, and survival during interbacterial warfare	32
Inter-kingdom lipid messengers sustain gut harmony	32
Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies	31
Keystone Pseudomonas species in the wheat phyllosphere microbiome mitigate Fusarium head blight by altering host pH	30
Gut microbiome and necrotizing enterocolitis: Understanding the connection to find a cure	30
Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis	30
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	30
Human gut bacterial metabolism drives Th17 activation and colitis	30
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	29
RNA editing of genomic neighbors controls antiviral response in fungi	29
Bug in the code: TB blocks DNA repair	29
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids	29
Bacterial defense systems exhibit synergistic anti-phage activity	29
Taking the pulse: Bacterial responses to intermittent antibiotics	28
A tough act to swallow: Streptococcus anginosus and gastric cancer	28
Microbiomes in Neverland	28
COVID-19 as a catalyst for vaccine manufacturing: A South African experience	28
Vivax malaria and Duffy antigen: Stop being so negative	27
Prospects for preventing cancer with anti-microbial prophylactic vaccines	27
Here, we grow	27
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin	27
Lactobacillus reuteri joins the liver autoimmune arena	27
Whack-a-virus: HIV-specific T cells play an exhausting game	27
Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements	27
Mitochondria sense bacterial lactate and drive release of neutrophil extracellular traps	27
Unbiased discovery of natural sequence variants that influence fungal virulence	27
Stress less: Viral mastery of the RNA G-quadruplex	27
Restoration of the human skin microbiome following immune recovery after hematopoietic stem cell transplantation	26
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals	26
Arresting microbiome development limits immune system maturation and resistance to infection in mice	26