Cell Host & Microbe

Papers
(The TQCC of Cell Host & Microbe is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Sowing the seeds of infection516
Microbial genome mining expedition unearths trove of antiviral defenses288
Selenium nanoboosting of plant-beneficial microbiome253
Candidalysin: An unlikely aide for fungal gut commensalism230
Breathe and bloom: Gut hypoxia limits C. albicans growth226
Waste as an antibacterial weapon206
Combatting superbugs using the evolutionary record of microbial warfare203
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution198
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects196
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites182
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine179
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy179
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes175
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation167
MFSD6 is an entry receptor for respiratory enterovirus D68165
Epithelial hypoxia maintains colonization resistance against Candida albicans164
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities161
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria158
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury149
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction148
Secretory IgA: Linking microbes, maternal health, and infant health through human milk147
Cad1 turns ATP into phage poison143
Help from commensals: β-hex to regulate gut immunity139
Two-for-one: Dual host-microbe functions of S. epidermidis Sph137
Immunity to fungi and vaccine considerations136
Select symbionts drive high IgA levels in the mouse intestine133
There and back again: Discovering antiviral and antiphage defenses using deep homology132
Beta-carbolines suppress vaginal inflammation132
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome130
Uniting against enteric invaders: IgA meets its microbial ally129
Tactical terminase: How a Salmonella prophage navigates oxidative stress129
How hosts accurately command bacteria for gut health126
Antibiotic treatment ignites a fire that lasts126
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism125
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics124
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection120
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology119
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant117
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes115
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry112
From top to bottom: Staphylococci in atopic dermatitis111
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis105
Overcoming drug resistance, the natural way104
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19103
Dietary environmental factors shape the immune defense against Cryptosporidium infection102
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut101
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites101
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7100
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA99
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism98
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.297
Decline in nitrosative stress drives antibiotic persister regrowth during infection94
Location matters in RSV protection93
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation92
A lung pathobiont story: Thinking outside the Koch’s postulate box92
“AHR-ming” host defense against cryptosporidiosis92
Gut IgA: Never fear, the super inducers are here91
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids90
Antibiotics fire up inflammation to cool vaccine responsiveness90
Predator-prey interplay: When chemical conversation turns deadly90
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding89
A single-cell liver atlas of Plasmodium vivax infection88
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster88
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity87
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein87
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection87
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease87
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection87
Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis86
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes86
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis86
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation84
A counterintuitive antibody cocktail disrupts coxsackievirus82
Goodbye PAM: Phage λ’s Red recombination system cripples PAMs and helps dodge CRISPR attacks82
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome82
When NOD ligands become antidotes81
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome79
On track to tackle dengue: History and future of NS4B ligands78
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer77
Infant gut DNA bacteriophage strain persistence during the first 3 years of life77
E. coli prophages encode an arsenal of defense systems to protect against temperate phages77
Brain development in premature infants: A bug in the programming system?76
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins76
Multi-arming ourselves against drug-resistant bacteria76
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity75
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway73
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox71
GOSpel for tiny allies71
Methylglyoxal is an antibacterial effector produced by macrophages during infection70
Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses69
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma69
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants69
The gut microbiome molecular complex in human health and disease68
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome67
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease67
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS67
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota67
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses66
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-266
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease65
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption65
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases65
AI in microbiome research: Where have we been, where are we going?64
Cutibacterium acnes evolution: One pore at a time63
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas1363
Commensal microbe regulation of skin cells in disease63
Unclouding Clostridiodes difficile virulence with systems biology63
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay63
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity62
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity62
“Indole-gence” for the mind61
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile60
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer59
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease59
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation58
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine58
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions57
Rethinking healthy eating in light of the gut microbiome57
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis57
Gut microbiome development and childhood undernutrition57
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission56
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis56
Microbial Cgr2 will let your Th17 cells ROR(γT)56
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy55
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes54
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut54
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species54
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization54
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses54
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history53
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring53
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis52
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage52
The gut-brain axis goes viral51
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis51
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden51
Even old foes can learn sweet new tricks51
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites51
Linking E. coli to fibrosis in Crohn’s disease50
MAMPs: A devil tamed becomes an angel50
Growing up: A NOD2 our microbes50
Viral mimicry protects from infection when you’re expecting49
Walking down the phosphorylation path to root immunity49
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response49
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics48
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity48
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants48
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination47
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance47
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence47
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma46
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages46
Going viral: The role of mobile genetic elements in bacterial immunity45
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes45
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants45
Multi-armed antibiotics for Gram-positive bacteria45
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response45
An expanded arsenal of immune systems that protect bacteria from phages44
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year44
A colon cancer “prequel”44
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology44
Stoking inflammasome fires in the COVID-19 neighborhood43
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis43
License to LAP43
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics43
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization43
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication42
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography42
Mimicry games: NPC-like MX2 condensates trap viruses42
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping42
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?42
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus42
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides41
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects41
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape41
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans41
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV41
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis41
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART41
Compensating P. falciparum artemisinin resistance40
The developing infant gut microbiome: A strain-level view40
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future39
It takes a plant village to raise a microbiome38
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation38
Mg and the microbiome: A liver-protective duo38
Bacterial molecular syringe for drug delivery38
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states38
Oh, how we have grown!37
Stitching together a healthy gut microbiome with fiber37
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein37
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy37
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth37
RTS,S today and tomorrow’s science37
BCG: From veins to correlates36
Designing boosting immunogens for HIV-1 vaccine development36
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut35
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans35
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity35
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes35
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure35
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont34
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut33
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes33
Happy families33
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens33
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein33
Fishing for obesity-related gut microbiome enterotype33
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