Cell Host & Microbe

Article	Citations
Sowing the seeds of infection	494
Combatting superbugs using the evolutionary record of microbial warfare	480
Microbial genome mining expedition unearths trove of antiviral defenses	291
Breathe and bloom: Gut hypoxia limits C. albicans growth	278
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	244
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	243
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	224
Selenium nanoboosting of plant-beneficial microbiome	210
MFSD6 is an entry receptor for respiratory enterovirus D68	194
Candidalysin: An unlikely aide for fungal gut commensalism	193
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	187
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	187
Engineered bacteria recycle tumor metabolic waste to boost immunotherapy	176
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	175
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	170
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	169
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	167
Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria	165
Epithelial hypoxia maintains colonization resistance against Candida albicans	159
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	158
Cad1 turns ATP into phage poison	152
Help from commensals: β-hex to regulate gut immunity	150
Two-for-one: Dual host-microbe functions of S. epidermidis Sph	146
Immunity to fungi and vaccine considerations	145
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	145

Select symbionts drive high IgA levels in the mouse intestine	139
There and back again: Discovering antiviral and antiphage defenses using deep homology	138
Beta-carbolines suppress vaginal inflammation	134
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	128
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	128
Tactical terminase: How a Salmonella prophage navigates oxidative stress	127
Antibiotic treatment ignites a fire that lasts	126
Uniting against enteric invaders: IgA meets its microbial ally	126
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	125
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	124
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	123
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	123
From top to bottom: Staphylococci in atopic dermatitis	122
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	120
Overcoming drug resistance, the natural way	115
Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis	115
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	115
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	114
A single-cell liver atlas of Plasmodium vivax infection	113
Decline in nitrosative stress drives antibiotic persister regrowth during infection	113
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	112
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	111
Location matters in RSV protection	109
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	103
“AHR-ming” host defense against cryptosporidiosis	101
A lung pathobiont story: Thinking outside the Koch’s postulate box	101
Systematic reconstruction of an effector-gene network reveals determinants of Salmonella cellular and tissue tropism	99
Gut IgA: Never fear, the super inducers are here	99
Dietary environmental factors shape the immune defense against Cryptosporidium infection	98
Predator-prey interplay: When chemical conversation turns deadly	97
Antibiotics fire up inflammation to cool vaccine responsiveness	96
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	96
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	95
Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis	94
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	91
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	91
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection	91
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	90
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	87
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	87
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	87
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	87
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	86
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	86
Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7	85
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	85
When NOD ligands become antidotes	84
A counterintuitive antibody cocktail disrupts coxsackievirus	84
Goodbye PAM: Phage λ’s Red recombination system cripples PAMs and helps dodge CRISPR attacks	84
Multi-arming ourselves against drug-resistant bacteria	83

Strong humoral immune responses against SARS-CoV-2 Spike after BNT162b2 mRNA vaccination with a 16-week interval between doses	83
Brain development in premature infants: A bug in the programming system?	83
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	83
On track to tackle dengue: History and future of NS4B ligands	82
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	82
GOSpel for tiny allies	82
AI in microbiome research: Where have we been, where are we going?	81
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2	79
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	77
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	77
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	76
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	76
The gut microbiome molecular complex in human health and disease	75
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	75
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	74
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	74
Methylglyoxal is an antibacterial effector produced by macrophages during infection	71
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	71
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	71
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	70
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	69
Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants	67
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	67
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	67
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	67
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer	67
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	66
Cutibacterium acnes evolution: One pore at a time	66
Unclouding Clostridiodes difficile virulence with systems biology	66
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	64
“Indole-gence” for the mind	64
Predictive regulatory and metabolic network models for systems analysis of Clostridioides difficile	63
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	63
Commensal microbe regulation of skin cells in disease	63
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	63
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	62
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	61
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	61
Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity	61
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	61
Rethinking healthy eating in light of the gut microbiome	61
Gut microbiome development and childhood undernutrition	60
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	60
Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission	60
Vaccinia virus E3 prevents sensing of Z-RNA to block ZBP1-dependent necroptosis	59
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	57
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	57
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	57
Microbial Cgr2 will let your Th17 cells ROR(γT)	57
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	56
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	56
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	56
Global COVID-19 vaccine inequity: The scope, the impact, and the challenges	56
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	54
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	54
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	53
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	52
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	51
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	51
The gut-brain axis goes viral	51
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	51
Linking E. coli to fibrosis in Crohn’s disease	50
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	50
Even old foes can learn sweet new tricks	50
MAMPs: A devil tamed becomes an angel	50
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response	50
Growing up: A NOD2 our microbes	50
Walking down the phosphorylation path to root immunity	50
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	49
Viral mimicry protects from infection when you’re expecting	49
Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	49
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	49
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	48
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	48
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	48
Going viral: The role of mobile genetic elements in bacterial immunity	47
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	47
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	46
A calmodulin-binding transcription factor links calcium signaling to antiviral RNAi defense in plants	46
An expanded arsenal of immune systems that protect bacteria from phages	46

Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	45
A colon cancer “prequel”	45
License to LAP	45
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	45
Stoking inflammasome fires in the COVID-19 neighborhood	45
Multi-armed antibiotics for Gram-positive bacteria	45
Mimicry games: NPC-like MX2 condensates trap viruses	44
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	44
HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization	44
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	43
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	43
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	42
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	42
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	42
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	42
Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides	42
The developing infant gut microbiome: A strain-level view	42
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	42
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	41
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	41
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	41
The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping	41
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	41
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	40
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	40
It takes a plant village to raise a microbiome	40
Compensating P. falciparum artemisinin resistance	40
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	40
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	40
Bacterial molecular syringe for drug delivery	40
Mg and the microbiome: A liver-protective duo	40
RTS,S today and tomorrow’s science	39
Stitching together a healthy gut microbiome with fiber	39
Oh, how we have grown!	39
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	38
BCG: From veins to correlates	38
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	37
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	37
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	37
Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans	37
Designing boosting immunogens for HIV-1 vaccine development	37
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	37
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	37
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	37
Long live the king: Toxoplasma gondii nucleomodulin inhibits necroptotic cell death	36
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	36
Happy families	36
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	36
Cryptosporidium modifies intestinal microvilli through an exported virulence factor	35
Gut dopamine kick: How gut microbes turn on host receptors to fight pathogens	35
Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis	35
Bacterial defense systems exhibit synergistic anti-phage activity	35
Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids	35