Cell Host & Microbe

Article	Citations
Waste as an antibacterial weapon	391
Microbial genome mining expedition unearths trove of antiviral defenses	387
Sowing the seeds of infection	372
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury	330
Engineered probiotics recruit CAR macrophages and establish immune memory to eradicate heterogeneous glioblastoma in mice	329
The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction	269
Crosstalk between three CRISPR-Cas types enables primed type VI-A adaptation in Listeria seeligeri	242
Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine	240
MFSD6 is an entry receptor for respiratory enterovirus D68	234
Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites	218
A secondary metabolite drives intraspecies antagonism in a gut symbiont that is inhibited by cell-wall acetylation	197
Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species- and strain-level diversity and evolution	194
An infant nasal microbial gene atlas uncovers intervention-driven microbiome shifts and salt-resistant pathogen expansion	182
Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities	178
Epithelial hypoxia maintains colonization resistance against Candida albicans	171
Breathe and bloom: Gut hypoxia limits C. albicans growth	171
Secretory IgA: Linking microbes, maternal health, and infant health through human milk	169
Pseudomonas infections persisting after CFTR modulators are widespread throughout the lungs and drive lung inflammation	169
Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects	166
When predators meet the matrix: Natural resistance via amyloid fibers	164
Selenium nanoboosting of plant-beneficial microbiome	162
Hide and seek: Cryptococcus evasion of microglial sensing enables meningitis	159
Combatting superbugs using the evolutionary record of microbial warfare	157
Microbial byproducts determine reproductive fitness of free-living and parasitic nematodes	156
Candidalysin: An unlikely aide for fungal gut commensalism	156

A CLOCK-targeting lncRNA induces trained immunity against tuberculosis	155
There and back again: Discovering antiviral and antiphage defenses using deep homology	144
Beta-carbolines suppress vaginal inflammation	143
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism	137
How hosts accurately command bacteria for gut health	135
Immunity to fungi and vaccine considerations	135
Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry	134
From top to bottom: Staphylococci in atopic dermatitis	133
Uniting against enteric invaders: IgA meets its microbial ally	130
Tactical terminase: How a Salmonella prophage navigates oxidative stress	129
Antibiotic treatment ignites a fire that lasts	128
Cad1 turns ATP into phage poison	125
A bacterial signal coordinates plant-microbe fitness trade-off to enhance sulfur deficiency tolerance in plants	122
Select symbionts drive high IgA levels in the mouse intestine	121
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics	120
Evolution of root nodule symbiosis via paleopolyploidy and modular pathway rewiring	118
Help from commensals: β-hex to regulate gut immunity	118
Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant	117
Conspecific versus heterospecific transmission shapes host specialization of the phyllosphere microbiome	117
A broadly distributed predicted helicase/nuclease confers phage resistance via abortive infection	115
Impact of a 7-day homogeneous diet on interpersonal variation in human gut microbiomes and metabolomes	115
Subtle, persistent shaping of the gut microbiome by host genes: A critical determinant of host biology	115
Lost and found: Reconstituting PRR immune function through co-receptor transfer	114
“AHR-ming” host defense against cryptosporidiosis	113
Gut IgA: Never fear, the super inducers are here	109
Predator-prey interplay: When chemical conversation turns deadly	108
Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes	107
Enhanced neutralization of SARS-CoV-2 variant BA.2.86 and XBB sub-lineages by a tetravalent COVID-19 vaccine booster	106
Antibiotics fire up inflammation to cool vaccine responsiveness	105
Dietary environmental factors shape the immune defense against Cryptosporidium infection	104
A single-cell liver atlas of Plasmodium vivax infection	103
Multiple introductions and recombination events underlie the emergence of a hyper-transmissible Cryptosporidium hominis subtype in the USA	102
A lung pathobiont story: Thinking outside the Koch’s postulate box	101
Decline in nitrosative stress drives antibiotic persister regrowth during infection	100
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19	99
A key genetic factor governing arabinan utilization in the gut microbiome alleviates constipation	98
A mucin-regulated adhesin determines the spatial organization and inflammatory character of a bacterial symbiont in the vertebrate gut	98
One population, multiple lifestyles: Commensalism and pathogenesis in the human mycobiome	96
Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection	95
Neutralization of SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, and BA.2	95
Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein	92
Exclusive enteral nutrition initiates individual protective microbiome changes to induce remission in pediatric Crohn’s disease	92
The gut microbiome: Bridging medications and clinical outcomes post stem cell transplantation	91
MX2 forms nucleoporin-comprising cytoplasmic biomolecular condensates that lure viral capsids	90
Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase	89
Precision modulation of dysbiotic adult microbiomes with a human-milk-derived synbiotic reshapes gut microbial composition and metabolites	87
On-person adaptive evolution of Staphylococcus aureus during treatment for atopic dermatitis	86
Microbiota alert: Proteobacteria consume arginine to dampen omental antitumor immunity	85
RSV and rhinovirus increase pneumococcal carriage acquisition and density, whereas nasal inflammation is associated with bacterial shedding	84
When NOD ligands become antidotes	83

A counterintuitive antibody cocktail disrupts coxsackievirus	83
GOSpel for tiny allies	82
The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome	81
Restoring a gut Bifidobacterium community in early infancy	81
Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins	81
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox	80
Bacteria exploit viral dormancy to establish CRISPR-Cas immunity	79
The gut microbiome molecular complex in human health and disease	79
AI in microbiome research: Where have we been, where are we going?	78
A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases	78
Multi-arming ourselves against drug-resistant bacteria	78
Systems virology as a cornerstone for pandemic responsiveness: A G2P-Japan perspective	77
Infant gut DNA bacteriophage strain persistence during the first 3 years of life	76
Microbes as architects of colonic patterning	74
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome	74
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system	72
Methylglyoxal is an antibacterial effector produced by macrophages during infection	72
Bacteroides sphingolipids promote anti-inflammatory responses through the mevalonate pathway	71
E. coli prophages encode an arsenal of defense systems to protect against temperate phages	71
Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS	70
Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication	69
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease	69
Salmonella re-engineers the intestinal environment to break colonization resistance in the presence of a compositionally intact microbiota	68
Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease	68
Obesity-enriched gut microbe degrades myo-inositol and promotes lipid absorption	68
Bifidobacterium longum promotes postoperative liver function recovery in patients with hepatocellular carcinoma	68
Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses	67
“Indole-gence” for the mind	66
Thanks, but no thanks: Cholera pathogen keeps incoming DNA at bay	66
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13	66
Antibiotic-induced gut microbiome perturbation alters the immune responses to the rabies vaccine	65
Commensal microbe regulation of skin cells in disease	65
The Africa COVID-19 legacy—Improved vaccinology for pandemic preparedness	64
Metabolic cross-feeding of a dietary antioxidant enhances anaerobic energy metabolism by human gut bacteria	64
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation	64
All systems go: CRISPR crosstalk for enhanced immunity	64
A global survey of taxa-metabolic associations across mouse microbiome communities	64
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions	63
Gut microbiome development and childhood undernutrition	62
Host-microbe interaction paradigms in acute and recurrent vulvovaginal candidiasis	62
An interplay between human genetics and intratumoral microbiota in the progression of colorectal cancer	62
Rethinking healthy eating in light of the gut microbiome	62
Oncomicrobial vaccines: The potential for a Fusobacterium nucleatum vaccine to improve colorectal cancer outcomes	61
Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease	61
Gut bacteria help the brain with an oil change	61
Symbiotic Firmicutes establish mutualism with the host via innate tolerance and resistance to control systemic immunity	61
Outsmarting the wicked smart: Using chemistry to overcome bacterial anti-viral systems	60
Conversation between host and gut microbiota unveils a “silver bullet” therapeutic option for chemotherapy	60
Bacterial entrapment of a fungal carbon repressor prevents plant colonization	60
Protist predators engineer bacterial metabolic cooperation	59
Environmental and maternal imprints on infant gut metabolic development	58
The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage	58
Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history	57
Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis	57
Bacterial homologs of innate eukaryotic antiviral defenses with anti-phage activity highlight shared evolutionary roots of viral defenses	57
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden	57
Spatially resolved lipidomics shows conditional transfer of lipids produced by Bacteroides thetaiotaomicron into the mouse gut	57
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis	56
Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species	56
Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites	56
The RNA landscape of the human commensal Segatella copri reveals a small RNA essential for gut colonization	56
Maternal gestational diabetes mellitus associates with altered gut microbiome composition and head circumference abnormalities in male offspring	55
Growing up: A NOD2 our microbes	55
A. baumannii’s nutrient tug-of-war	54
Walking down the phosphorylation path to root immunity	54
Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants	53
Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes	53
Multi-armed antibiotics for Gram-positive bacteria	53
Linking E. coli to fibrosis in Crohn’s disease	52
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response	52
Microbiota utilization of intestinal amino acids modulates cancer progression and anticancer immunity	51
MAMPs: A devil tamed becomes an angel	51
Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance	51
Viral mimicry protects from infection when you’re expecting	51
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages	51
Going viral: The role of mobile genetic elements in bacterial immunity	50
Lactate production by tumor-resident Staphylococcus promotes metastatic colonization in lung adenocarcinoma	49
Deep learning helps fight against antibiotic resistance	49
Mycobacterial phage TM4 requires a eukaryotic-like Ser/Thr protein kinase to silence and escape anti-phage immunity	49
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts	49

Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination	49
Comprehensive analysis of Mycobacterium tuberculosis genomes reveals genetic variations in bacterial virulence	48
An expanded arsenal of immune systems that protect bacteria from phages	46
Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year	46
Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial	46
Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology	45
Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics	45
Bacteria block host cell death by protein cut-and-paste	44
Mimicry games: NPC-like MX2 condensates trap viruses	44
Stoking inflammasome fires in the COVID-19 neighborhood	44
The impact of COVID-19 on children and lessons for pandemic preparedness	44
Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics	44
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly	43
Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin	43
Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART	43
The microbial metabolite imidazole propionate modulates hypothalamic activity and stress-induced behaviors	42
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape	42
The developing infant gut microbiome: A strain-level view	41
Prenatal antibiotics reduce breast milk IgA and induce dysbiosis in mouse offspring, increasing neonatal susceptibility to bacterial sepsis	41
Gut microbial enzymes and metabolic dysfunction-associated steatohepatitis: Function, mechanism, and therapeutic prospects	41
Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis	41
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflicts by acquiring spacers in trans	40
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication	40
Fungal resistance in rice is restored by interfamily transfer of an evolutionarily lost co-receptor	40
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography	40
The vagina question: Can maternal vaginal fluid impact the infant gut microbiome and neurodevelopment?	40
Gut microbiota-derived indole-3-lactic acid suppresses anti-PD-1 efficacy in esophageal squamous cell carcinoma	39
A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV	39
Crisping up Lactobacillus vaginal live biotherapeutics	39
The DanRI regulatory system in uropathogenic Escherichia coli subverts neutrophil responses	39
Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus	39
The skin microbiota drives cutaneous immune checkpoint inhibitor toxicity in genetically susceptible mice	39
BCG: From veins to correlates	38
It takes a plant village to raise a microbiome	38
A new piece of the microbiota pie: Mining ‘omics for DNA inversion states	38
Pregnancy-associated morbidity and mortality during pandemics: Looking to the past in order to prepare for the future	38
Bacteria renew an OLD protein to cleave host tRNAs and block phage translation	38
Gut microbiota and metabolites drive chronic sickle cell disease pain in mice	38
Stitching together a healthy gut microbiome with fiber	38
The HY5-NPR1 module governs light-dependent virulence of a plant bacterial pathogen	37
Designing boosting immunogens for HIV-1 vaccine development	37
Microbial communities in semi-mature oak trees are resilient to drought, nutrient limitation, and pathogen challenge	37
Molecular basis for inhibition of type III-B CRISPR-Cas by an archaeal viral anti-CRISPR protein	37
One size might fit all: Indole-3-propionic acid potentiates pan-cancer immunotherapy	37
RTS,S today and tomorrow’s science	37
Differences in carbon metabolic capacity fuel co-existence and plasmid transfer between Salmonella strains in the mouse gut	36
Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein	36
The female urogenital microbiome: Ecological insights, therapeutic strategies, and molecular mechanisms	36
Response, resistance, and recovery of gut bacteria to human-targeted drug exposure	36
Metagenomic selections reveal diverse antiphage defenses in human and environmental microbiomes	36
Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity	36
Individual leaf microbiota tunes a genetic regulatory network to promote leaf growth	36
‘Insane in the membrane’: 2′,3′-cGAMP triggers filamentous phage defense	36
Sensing a pattern: Overlapping immunity in bacteria and eukaryotes	35
Bacterial molecular syringe for drug delivery	35
Bioengineered gut bacterium synthesizing levodopa alleviates motor deficits in models of Parkinson’s disease	35
Won’t you be my neighbor? The importance of biogeography and nutrient niches in the gut	35
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont	35
Charting a phage genome atlas	35
Mg and the microbiome: A liver-protective duo	35