OOIR: Observatory of International Research

Papers

(The median citation count of Biomicrofluidics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Lab-on-a-disk extraction of PBMC and metered plasma from whole blood: An advanced event-triggered valving strategy	53
I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles	51
Recent advances in label-free optical, electrochemical, and electronic biosensors for glioma biomarkers	40
Dynamic cellular responses to gravitational forces: Exploring the impact on white blood cell(s)	29
Recent advances in microscale techniques for red blood cells manipulation	24
Microflows in two-generation alveolar cells at an acinar bifurcation	24
Epithelial and mesenchymal phenotypes determine the dynamics of circulating breast tumor cells in microfluidic capillaries under chemotherapy-induced stress	24
Thermal bubble single-cell printing chip: High-throughput, wide-field, and efficient	24
Trajectory analysis of Bacillus subtilis in micro-droplets	24
High-throughput deterministic pairing and coculturing of single cells in a microwell array using combined hydrodynamic and recirculation flow captures	24
Nanogap traps for passive bacteria concentration and single-point confocal Raman spectroscopy	24
Design of a flexing organ-chip to model in situ loading of the intervertebral disc	21
Potential of the acoustic micromanipulation technologies for biomedical research	19
Long-term cultured microvascular networks on chip for tumor vascularization research and drug testing	19
Robotic automation of droplet microfluidics	18
Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro	18
Preface to the Special Topic: Microfluidics, Circulating Biomarkers and Cancer	17
Artificial intelligence-driven electrochemical immunosensing biochips in multi-component detection	16
Microfluidic sweat patch based on capillary force and evaporation pump for real-time continuous sweat analysis	15
Simultaneous high-throughput particle-bacteria separation and solution exchange via in-plane and out-of-plane parallelization of microfluidic centrifuges	15
Recent advances in microfluidic-based spectroscopic approaches for pathogen detection	15
pH effects on capture efficiency and deposition patterns in sessile droplet immunoassays: An XDLVO analysis	14
The enhancement of DNA fragmentation in a bench top ultrasonic water bath with needle-induced air bubbles: Simulation and experimental investigation	14
Liver-on-a-chip: Considerations, advances, and beyond	14
Microfluidic-to-macrofluidic: A simple in vitro model of atherosclerosis induced by fluidic stimulation	14

Digital microfluidics methods for nucleic acid detection: A mini review	13
A microfluidic sucrose gap platform using trilaminar flow with on-chip switching and novel calibration: Challenges and limitations	13
Investigating the effect of phospholipids on droplet formation and surface property evolution in microfluidic devices for droplet interface bilayer (DIB) formation	13
A brief overview of passive microvalves in microfluidics: Mechanism, manufacturing, and applications	13
Improved acoustic holograms using simulated annealing	12
Soluto-thermal Marangoni convection in stationary micro-bioreactors on heated substrates: Tool for in vitro diagnosis of PSA	11
Microfluidic supercritical CO2 applications: Solvent extraction, nanoparticle synthesis, and chemical reaction	11
Mechanically mediated cargo delivery to cells using microfluidic devices	11
Lateral force separation of biopolymers using an atomic force microscope	11
What is the future of electrical impedance spectroscopy in flow cytometry?	11
Paper-based microfluidics: Analyte-driven imbibition under the lens	10
Application and prospect of microfluidic devices for rapid assay of cell activities in the tumor microenvironment	10
Parallel study of transient dosing of antibiotics in a microfluidic device	10
Cell pairing for biological analysis in microfluidic devices	10
Laser induced graphanized microfluidic devices	10
Biphasic flow dynamics and polarized mass transportation in branched hepatic sinusoids	10
Manually pressurized droplet digital PCR chip for rapid SARS-CoV-2 diagnostics	9
On-chip dielectrophoretic device for cancer cell manipulation: A numerical and artificial neural network study	9
Recent advances in the understanding of alveolar flow	9
A miniaturized culture platform for control of the metabolic environment	9
Brain organoid-on-a-chip: A next-generation human brain avatar for recapitulating human brain physiology and pathology	9
Low-cost and convenient fabrication of polymer micro/nanopores with the needle punching process and their applications in nanofluidic sensing	9
Continuous separation of bacterial cells from large debris using a spiral microfluidic device	9
High-Q WGM microcavity-based optofluidic sensor technologies for biological analysis	8
Confinement effect on the microcapillary flow and shape of red blood cells	8
Design automation for deterministic lateral displacement by leveraging deep Q-network	8
Micromixing within microfluidic devices: Fundamentals, design, and fabrication	8
Air microfluidics-enabled soft robotic transtibial prosthesis socket liner toward dynamic management of residual limb contact pressure and volume fluctuation	8
Microfluidics-enabled functional 3D printing	8
Perspective on fluorescence cell imaging with ionophore-based ion-selective nano-optodes	7
Mimicking blood and lymphatic vasculatures using microfluidic systems	7
Recent advances in microfluidic-based cancer immunotherapy-on-a-chip strategies	7
Hepatic spheroid-on-a-chip: Fabrication and characterization of a spheroid-based in vitro model of the human liver for drug screening applications	7
Organ-specific vasculature-on-a-chip systems	7
Engineering porous membranes mimicking in vivo basement membrane for organ-on-chips applications	7
Addressable microfluidics technology for non-sacrificial analysis of biomaterial implants in vivo	7
An in vitro multi-organ microphysiological system (MPS) to investigate the gut-to-brain translocation of neurotoxins	7
Microfluidic synthesis as a new route to produce novel functional materials	7
Faradaic-free electrokinetic nucleic acid amplification (E-NAAMP) using localized on-chip high frequency Joule heating	6
From specialization to broad adoption: Key trends in droplet microfluidic innovations enhancing accessibility to non-experts	6
Toward droplets displaying life-like interaction behaviors	6
Extracellular vesicle and lipoprotein diagnostics (ExoLP-Dx) with membrane sensor: A robust microfluidic platform to overcome heterogeneity	6
Referee acknowledgment for 2021	6
Wall shear gradient dependent thrombosis studied in blood-on-a-chip with stenotic, branched, and valvular constructions	6
Organoid-on-a-chip: Current challenges, trends, and future scope toward medicine	6
Naturally derived colloidal rods in microfluidic flows	6
The interaction of vortical flows with red cells in venous valve mimics	6
Developing a piezoresistive sensor based bionic neurological intraoperative monitoring system for spine surgery skill training	6
Nano/microfluidic device for high-throughput passive trapping of nanoparticles	6
Dean vortex-enhanced blood plasma separation in self-driven spiral microchannel flow with cross-flow microfilters	6

A high-throughput flowless microfluidic single and multi-solute concentration gradient generator: Design and parametric study	6
Review on bile dynamics and microfluidic-based component detection: Advancing the understanding of bilestone pathogenesis in the biliary tract	5
Hematocrit skewness along sequential bifurcations within a microfluidic network induces significant changes in downstream red blood cell partitioning	5
Inertial microfluidics in contraction–expansion microchannels: A review	5
Nanoextraction based on surface nanodroplets for chemical preconcentration and determination	5
The mechanism of biofilm detachment in porous medium under flow field	5
Microfluidic technology for multiple single-cell capture	5
Microneedle arrays integrated with microfluidic systems: Emerging applications and fluid flow modeling	5
Ultraviolet control of bacterial biofilms in microfluidic chips	5
Artificial blood for therapeutic and laboratory usage: Where do we stand?	5
Universal correlation for the critical diameter of deterministic lateral displacement devices with polygonal posts	5
Tunable motile sperm separation based on sperm persistence in migrating through shear barriers	5
Phenotyping of rare circulating cells in the blood of non-metastatic breast cancer patients using microfluidic Labyrinth technology	5
Microfluidic system for near-patient extraction and detection of miR-122 microRNA biomarker for drug-induced liver injury diagnostics	5
Microfluidic wearable electrochemical sweat sensors for health monitoring	5
Microfluidic technologies for advanced antimicrobial susceptibility testing	5
Visualizing liquid distribution across hyphal networks with cellular resolution	5
Paper-based analytical devices for point-of-care blood tests	5
Inertial focusing of particles and cells in the microfluidic labyrinth device: Role of sharp turns	5
Titrating chimeric antigen receptors on CAR T cells enabled by a microfluidic-based dosage-controlled intracellular mRNA delivery platform	5
Microfluidic detection of viruses for human health	4
Standardizing characterization of membrane active peptides with microfluidics	4
Giardia purification from fecal samples using rigid spiral inertial microfluidics	4
The centrifugal viscometer	4
Photo-addressable microwell devices for rapid functional screening and isolation of pathogen inhibitors from bacterial strain libraries	4
A simple acoustofluidic device for on-chip fabrication of PLGA nanoparticles	4
Spheroids formation in large drops suspended in superhydrophobic paper cones	4
Acoustohydrodynamic micromixers: Basic mixing principles, programmable mixing prospectives, and biomedical applications	4
Directed colloidal assembly and banding via DC electrokinetics	4
Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications	4
Investigation of pressure balance in proximity of sidewalls in deterministic lateral displacement	4
Microfluidic pumps for cell sorting	4
A bionic mimosa soft robot based on a multi-responsive PNIPAM-PEGDA hydrogel composition	3
A traveling surface acoustic wave-based micropiezoactuator: A tool for additive- and label-free cell lysis	3
Temperature-dependent microfluidic impedance spectroscopy for non-invasive biofluid characterization	3
Microfluidic production of monodisperse emulsions for cosmetics	3
Microbial stir bars: Light-activated rotation of tethered bacterial cells to enhance mixing in stagnant fluids	3
Automatic feedback control by image processing for mixing solutions in a microfluidic device	3
Microfluidic devices fitted with “flowver” paper pumps generate steady, tunable gradients for extended observation of chemotactic cell migration	3
All polymer microfluidic chips—A fixed target sample delivery workhorse for serial crystallography	3
Surface-dominant micro/nanofluidics for efficient green energy conversion	3
Microfluidic cell sorter sample preparation for genomic assays	3
In situ 3D polymerization (IS-3DP): Implementing an aqueous two-phase system for the formation of 3D objects inside a microfluidic channel	3
Water filling of microcavities	3
Harnessing the power of Microscale AcoustoFluidics: A perspective based on BAW cancer diagnostics	3
A novel air microfluidics-enabled soft robotic sleeve: Toward realizing innovative lymphedema treatment	3
Advances in point-of-care genetic testing for personalized medicine applications	3
Dual-wavelength volumetric stereolithography of multilevel microfluidic devices	3
Rosette-induced separation of T cells by acoustophoresis	3
A perspective on computer vision in biosensing	3
The role of acoustofluidics and microbubble dynamics for therapeutic applications and drug delivery	3
Scaling up microdroplet production with post-array devices	2
Integrating an aerosolized drug delivery device with conventional static cultures and a dynamic airway barrier microphysiological system	2
Emerging trends in functional molecularly imprinted polymers for electrochemical detection of biomarkers	2
Strain-induced self-rolled-up microtubes for multifunctional on-chip microfluidic applications	2
Role of microfluidics in accelerating new space missions	2
Nucleation kinetics of calcium oxalate monohydrate as a function of pH, magnesium, and osteopontin concentration quantified with droplet microfluidics	2
A simple guideline for designing droplet microfluidic chips to achieve an improved single (bio)particle encapsulation rate using a stratified flow-assisted particle ordering method	2
Microfluidics for the biological analysis of atmospheric ice-nucleating particles: Perspectives and challenges	2
Low-cost and cleanroom-free prototyping of microfluidic and electrochemical biosensors: Techniques in fabrication and bioconjugation	2
Engineering advancements in microfluidic systems for enhanced mixing at low Reynolds numbers	2
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration	2
Scaling microfluidic throughput with flow-balanced manifolds to simply control devices with multiple inlets and outlets	2
A passive and programmable 3D paper-based microfluidic pump for variable flow microfluidic applications	2
Efficient single-cell oxygen consumption rate characterization based on frequency domain fluorescence lifetime imaging microscopy measurement and microfluidic platform	2
Interpretation of cell mechanical experiments in microfluidic systems depend on the choice of cellular shape descriptors	2
Vascularized platforms for investigating cell communication via extracellular vesicles	2
Droplet-based valveless microfluidic system for phage-display screening against spheroids	2
Microfluidic-assisted fiber production: Potentials, limitations, and prospects	2
A high throughput blood–brain barrier model incorporating shear stress with improved predictive power for drug discovery	2
Microfluidics-based patient-derived disease detection tool for deep learning-assisted precision medicine	2
Deep learning assisted mechanotyping of individual cells through repeated deformations and relaxations in undulating channels	2
Phototactic microswimmers in pulsatile flow: Toward a novel harvesting method	2
Microfluidics based bioimaging with cost-efficient fabrication of multi-level micrometer-sized trenches	2
A flexible strategy to fabricate trumpet-shaped porous PDMS membranes for organ-on-chip application	2
Micropatterning of functional lipid bilayer assays for quantitative bioanalysis	2
RapidQ: A reader-free microfluidic platform for the quantitation of antibodies against the SARS-CoV-2 spike protein	2