OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Stem Cell is 78. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Releasing the brake on protein synthesis in hematopoietic stem cells	330
Know thy neighbor: Modeling spatiotemporal cell-fate patterns in a neural stem cell niche	250
Can’t touch this: Stromal-mediated ductal proliferation	228
Human blastoids 3.0	227
Early-career researchers in the time of COVID-19: Adapting to uncertainty	210
Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia	209
Incompatibility in cell adhesion constitutes a barrier to interspecies chimerism	208
Engineered hiPSC-derived vascular graft brings hope for thrombosis-free vascular therapy	195
Systems immunology analysis of human immune organoids identifies host-specific correlates of protection to different influenza vaccines	184
Region-specific cellular and molecular basis of liver regeneration after acute pericentral injury	167
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate	166
A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease	164
New dog, old tricks: Developmental programs resurface in inflammation	151
Introductions to the community: Early-career researchers in the time of COVID-19	149
T cell immunotherapy for cardiac fibrosis: mRNA starts the CAR	143
Cultivating mentorship, cooperation, and community during COVID-19 and beyond	143
Having a blast(oid): Modeling human embryo peri-implantation development with blastoids	142
Human 8-cell-like cells discovered	142
Successful organoid-mediated generation of iPSC-derived CAR-T cells	140
Pervasive donor DNA integration defies precision gene editing of hematopoietic stem cells	137
Ensemble of old and new techniques escorts ESCs to bona fide embryo-like structures	134
Uncovering the origins and lineage markers of human heart fields	133
Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity	131
Pandemic city: Village-in-a-dish unlocks dynamic genetic effects in the brain	129
Brain organoids restore cortical damage	127

Lymphatic endothelia stakeout cryptic stem cells	125
Addressing challenges for repairing adult spinal cord with insights from neonates	122
Genetic and non-genetic mechanisms of inflammation may promote transformation in leukemia	119
A deep learning platform to assess drug proarrhythmia risk	117
Stem cell-based islet replacement therapy in diabetes: A road trip that reached the clinic	116
hPSCs-derived Schwann cells serve for disease modeling and drug discovery	115
Cut out that YAPping: Mechanisms to reduce scar formation	113
Regrowing the heart, one TREE at a time	113
Genetic reporter for live tracing fluid flow forces during cell fate segregation in mouse blastocyst development	113
Alternative splicing of a chromatin modifier alters the transcriptional regulatory programs of stem cell maintenance and neuronal differentiation	111
Development, maturation, and maintenance of human prostate inferred from somatic mutations	110
Early stem cell aging in the mature brain	107
Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease	105
In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury	104
Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity	103
Mechano-oncogenic cytoskeletal remodeling drives leukemic transformation with mitochondrial vesicle-mediated STING activation	102
New monkey embryo models—it’s getting complicated	101
New readers and writers of RNA modifications unique to leukemia stem cells	101
Prolonged 3D culture unlocks black box of primate embryogenesis	100
TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate	100
Resolving organoid brain region identities by mapping single-cell genomic data to reference atlases	99
A subset of macrophages and monocytes in the mouse bone marrow express atypical chemokine receptor 1	99
Mini-colons predict drug toxicity in vitro	99
Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models	99
A one-way street recognition approach to mediate allogeneic immune cell therapies	99
Forward steps in organoid-based forward screening	98
An insulin hypersecretion phenotype precedes pancreatic β cell failure in MODY3 patient-specific cells	98
Clonal hematopoiesis driven by chromosome 1q/MDM4 trisomy defines a canonical route toward leukemia in Fanconi anemia	97
Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption	96
New guidelines for stem cell and embryo research from the ISSCR	96
Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization	95
Inflation comes before the fall: How epithelial stretch drives crypt fission	94
New York Stem Cell Foundation Robertson Investigators	94
Mobility mediates maturation: Synthetic substrates to enhance neural differentiation	93
A mechanical niche promotes the rejuvenation of blood stem cells	93
Direct chemical reprogramming of human cord blood erythroblasts to induced megakaryocytes that produce platelets	92
Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment	91
Regulation of advanced therapies in Europe: Are we on the right track?	91
Lung repair and regeneration: Advanced models and insights into human disease	91
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity	91
Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis	91
Oscillation steers differentiation	90
Apart and back again: Reestablished neuronal connections restore walking after paralysis	90
Acetate to the rescue: Acetyl-CoA facilitates placental development	89
Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer’s disease model	83
A distinct metabolic and epigenetic state drives trained immunity in HSC-derived macrophages from autoimmune mice	82
Modeling early gastrulation in human blastoids with DNA methylation patterns of natural blastocysts	82
Cell competition and the regulative nature of early mammalian development	81
An iron rheostat controls hematopoietic stem cell fate	81
Overcoming gene dosage barriers in mammalian development: An imprinting balancing act	81

Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease	80
Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals	79
Glioblastoma stem cell HISTArionics	78
Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation	78