OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Stem Cell is 76. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Induction of Multipotential Hematopoietic Progenitors from Human Pluripotent Stem Cells via Respecification of Lineage-Restricted Precursors	575
hPSCs-derived Schwann cells serve for disease modeling and drug discovery	227
Engineered heart tissue patches: A milestone in cardiac regenerative medicine	227
Regrowing the heart, one TREE at a time	220
Successful organoid-mediated generation of iPSC-derived CAR-T cells	215
Pancreatic acinar heterogeneity hijacks carcinogenesis and homeostasis	213
Prolonged 3D culture unlocks black box of primate embryogenesis	192
Oscillation steers differentiation	186
T cell immunotherapy for cardiac fibrosis: mRNA starts the CAR	178
Cut out that YAPping: Mechanisms to reduce scar formation	170
Modeling early gastrulation in human blastoids with DNA methylation patterns of natural blastocysts	159
A phenotypic brain organoid atlas and biobank for neurodevelopmental disorders	157
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes	149
Stage-specific H3K9me3 occupancy ensures retrotransposon silencing in human pre-implantation embryos	146
Human heart-macrophage assembloids mimic immune-cardiac interactions and enable arrhythmia disease modeling	145
Microglia depletion reduces human neuronal APOE4-related pathologies in a chimeric Alzheimer’s disease model	145
A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development	142
An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer	136
Brain organoids restore cortical damage	136
Exercise-induced Musclin determines the fate of fibro-adipogenic progenitors to control muscle homeostasis	134
Phase I clinical trial of intracerebroventricular transplantation of allogeneic neural stem cells in people with progressive multiple sclerosis	134
A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate	132
From β soloist to endocrine symphony: Subtype-complete islets conduct glucose harmony	131
Tissue morphology influences the temporal program of human brain organoid development	131
Increased cholesterol synthesis drives neurotoxicity in patient stem cell-derived model of multiple sclerosis	127

In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells	126
The single-cell and spatial transcriptional landscape of human gastrulation and early brain development	126
Retraction Notice to: Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells	118
IRF6 hits the sweet spot	118
Human biliary epithelial cells for regenerative medicine	117
Turning the tide: From fibrosis to regeneration following anti-fibrogenic cell vaccination	114
Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero	113
A post-middle-age crisis for CD47 and THBS1 that turns into a vicious cycle	112
Human stem cell-derived A10 dopaminergic neurons specifically integrate into mouse circuits and improve depression-like behaviors	112
Hypoimmune CD19 CAR T cells evade allorejection in patients with cancer and autoimmune disease	109
Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment	109
Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells	108
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson’s disease, STEM-PD	106
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells	105
Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development	102
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease	102
Perceiving the brain like never before	99
Development has the answer: Unraveling psychiatric disorders via thalamocortical organoids	98
The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes	97
Preclinical and dose-ranging assessment of hESC-derived dopaminergic progenitors for a clinical trial on Parkinson’s disease	96
Enchanted by the earliest stages of human life	96
An oncogenic enhancer encodes selective selenium dependency in AML	93
Unlocking human brain networks by assembling circuits in vitro and in vivo	92
3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy	91
Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification	91
Preclinical efficacy and safety of encapsulated proliferating human hepatocyte organoids in treating liver failure	91
AMD recapitulated in a 3D biomimetic: A breakthrough in retina tissue engineering	91
Sustained NF-κB activation allows mutant alveolar stem cells to co-opt a regeneration program for tumor initiation	89
Early human development and stem cell-based human embryo models	88
Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion	87
Progress in multicellular human cardiac organoids for clinical applications	87
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging	86
Retraction Notice to: shRNA Knockdown of Bmi-1 Reveals a Critical Role for p21-Rb Pathway in NSC Self-Renewal during Development	84
Revolutionizing islet transplantation with a preconditioning boost for beta cell survival	84
All roads lead to cholesterol: Modulating lipid biosynthesis in multiple sclerosis patient-derived models	83
Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons	83
Nanobioreactor detection of space-associated hematopoietic stem and progenitor cell aging	82
Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress	81
Rebuilding and rebooting immunity with stem cells	81
Adrenergic nerves regulate intestinal regeneration through IL-22 signaling from type 3 innate lymphoid cells	81
Fission impossible: Mitochondrial dynamics direct muscle stem cell fates	80
Neighborhood matters: Altered lipid metabolism in APOE4 microglia causes problems for neurons	80
Human Down syndrome microglia are up for a synaptic feast	80
Cognitive impairment in epilepsy progression: Adult neurogenesis loss at critical window	80
Video, ergo sum: The search for response to natural light	78
Mini kidney organoids deliver maximal drug screening impact	78
Organ function is preserved despite reorganization of niche architecture in the hair follicle	77
Integrated molecular-phenotypic profiling reveals metabolic control of morphological variation in a stem-cell-based embryo model	77
A reference human induced pluripotent stem cell line for large-scale collaborative studies	77
A human pluripotent stem cell-based somitogenesis model using microfluidics	77

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice	76
Epigenetic regulation of early human embryo development	76
Therapeutic intersections: Expanding benefits of CD19 CAR T cells from cancer to autoimmunity	76
Advancing cell therapy for neurodegenerative diseases	76