OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Biophysics is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Enzymology and Dynamics by Cryogenic Electron Microscopy	197
Free Energy Methods for the Description of Molecular Processes	178
Mapping Enzyme Landscapes by Time-Resolved Crystallography with Synchrotron and X-Ray Free Electron Laser Light	133
The Effects of Temperature on Cellular Physiology	127
Membrane Association of Intrinsically Disordered Proteins	115
The Expanded Central Dogma: Genome Resynthesis, Orthogonal Biosystems, Synthetic Genetics	111
Biophysical Modeling of Synaptic Plasticity	107
Nanomechanics of Blood Clot and Thrombus Formation	82
Mechanism of Activation of the Visual Receptor Rhodopsin	68
ATP-Independent Chaperones	67
From Nucleosomes to Compartments: Physicochemical Interactions Underlying Chromatin Organization	53
Collapse and Protein Folding: Should We Be Surprised That Biothermodynamics Works So Well?	51
Next-Generation Genetically Encoded Fluorescent Biosensors Illuminate Cell Signaling and Metabolism	50
Chaperonin Mechanisms: Multiple and (Mis)Understood?	48
Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes	48
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy	45
Structure and Mechanism of Human ABC Transporters	44
Bioenergetics and the Evolution of Cellular Traits	44
Molecular Mechanisms Underlying Neurotransmitter Release	42
Bacterial Electrophysiology	41
Waves in Embryonic Development	39
Bringing Structure to Cell Biology with Cryo-Electron Tomography	39
Mechanisms for DNA Interplay in Eukaryotic Transcription Factors	35
Unveiling the Intricate Connection: Cell Volume as a Key Regulator of Mechanotransduction	34
Statistical Thermodynamics of the Protein Ensemble: Mediating Function and Evolution	34

Coding From Binding? Molecular Interactions at the Heart of Translation	34
Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease	34