OOIR: Observatory of International Research

Papers

(The median citation count of Tissue Engineering Part A is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Bioprinting of a Liposomal Oxygen-Releasing Scaffold for Ovary Tissue Engineering	48
Effect of Microbial Stimuli and Bone Morphogenetic Protein 2 on Ectopic Bone Formation	42
TERMIS 2023 – European Chapter Manchester Central Conference Centre Manchester, UK March 28–31, 2023	38
Toward the Development of a Tissue Engineered Gradient Utilizing CRISPR-Guided Gene Modulation	36
Optimized Biomanufacturing for Treatment of Volumetric Muscle Loss Enables Physiomimetic Recovery	29
Human Induced Pluripotent Stem Cell Encapsulation Geometry Impacts Three-Dimensional Developing Human Engineered Cardiac Tissue Functionality	26
Cardiovascular Tissue Engineering and Regeneration: A Plead for Further Knowledge Convergence	25
Impact of Cell Seeding Density and Cell Confluence on Human Tissue Engineered Skeletal Muscle	24
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	23
TGFβ-1 and Healing of Bone Defects in Large Animal and Rabbit Models: A Systematic Review	23
Triply Periodic Minimal Surface-Based Scaffolds for Bone Tissue Engineering: A Mechanical, In Vitro and In Vivo Study	21
Call for Papers: Special Issue on Machine Learning in Tissue Engineering	21
Fast-Degrading Tissue-Engineered Vascular Grafts Lead to Increased Extracellular Matrix Cross-Linking Enzyme Expression	21
Hematoxylin and Eosin Architecture Uncovers Clinically Divergent Niches in Pancreatic Cancer	21
Collagen Vitrigel Membrane-Coated Nylon Line Prevents Stenosis After Conization of the Cervix Uteri	19
Tissue-Engineered Hepatocyte Sheets Supplemented with Adipose-Derived Stem Cells	19
Increasing Collagen to Bioink Drives Mesenchymal Stromal Cells-Chondrogenesis from Hyaline to Calcified Layers	18
Highly Porous Gas-Blown Hydrogels for Direct Cell Encapsulation with High Cell Viability	17
The Effects of Negative Pressure Therapy on Hair Growth of Mouse Models	17
Programming the Self-Organization of Endothelial Cells into Perfusable Microvasculature	16
Negative Printing for the Reinforcement of In Situ Tissue-Engineered Cartilage	16
Experiment-Based Validation of Corneal Lenticule Banking in a Health Authority-Licensed Facility	15
A Multilayer Nanofibrous Mat for the Topical Chemotherapy of the Positive Margin in Bladder Cancer	15
Tricultured Cell Sheets Develop into Functional Pancreatic Islet Tissue with a Vascular Network	15
Improved Mesenchymal Stem Cell Viability in High-Stiffness, Translational Cartilage Matrix Hydrogels	15

Acknowledgment of Reviewers 2024	14
Restoration of Pregnancy Function Using a GT/PCL Biofilm in a Rabbit Model of Uterine Injury	14
Transcriptomics Demonstrates Significant Biological Effect of Growing Stem Cells on RGD-Cotton Scaffold	14
Production of a Bioink Containing Decellularized Spinal Cord Tissue for 3D Bioprinting	14
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for Tissue Engineering Part A	14
Effect of Chitosan on Synovial Membrane Derived Cells and Anterior Cruciate Ligament Fibroblasts	14
Spatial Heterogeneity of Invading Glioblastoma Cells Regulated by Paracrine Factors	13
Silk Fibroin-Laponite Porous Microspheres as Cell Microcarriers for Osteogenic Differentiation	13
The Role of Matrix Stiffness and Viscosity on Lipid Phenotype and Fat Lineage Potential	13
Enhancing Bone Healing Through Localized Cold Therapy in a Murine Femoral Fracture Model	13
Regenerative Potential of Human Umbilical Cord Vein for Urethral Reconstruction in Male Rabbit Model	13
Characterization of the Temporomandibular Joint Disc Complex in the Yucatan Minipig	12
Deep Learning Augmented Osteoarthritis Grading Standardization	12
Targeted Activation of G-Protein Coupled Receptor-Mediated Ca²⁺ Signaling Drives Enhanced Cartilage-Like Matrix Formation	12
Enzyme-Mediated Nerve Growth Factor Release from Nanofibers Using Gelatin Microspheres	11
Smart Design for Hybrid Bioprinting of Scalable and Viable Tissue Constructs	11
A Quick and Efficient Method for the Generation of Immunomodulatory Mesenchymal Stromal Cell from Human Induced Pluripotent Stem Cell	11
Dual Delivery of BMP2 and IGF1 Through Injectable Hydrogel Promotes Cranial Bone Defect Healing	11
Editorial for Special Issue on Artificial Intelligence in Tissue Engineering and Biology	11
Self-Assembly of Tooth Root Organoid from Postnatal Human Dental Stem Cells	11
Perspectives on Recent Developments and Directions in Tissue Engineering and Regenerative Medicine	11
Call for Papers: Special Issue on Modulation of the Immune System to Improve Tissue Regeneration Strategies	11
Transcriptomic Regulation of Macrophages by Matrix-Bound Nanovesicle-Associated Interleukin-33	11
In Vitro Model Extracellular Matrix Maturation Under Variable Stress Conditions	10
Small-Caliber Vascular Grafts Engineered from Decellularized Leaves and Cross-Linked Gelatin	10
Inductive Remodeling of Extracellular Matrix Scaffolds in the Temporomandibular Joint of Pigs	10
Assessing Efficacy of Afatinib toward Elastic Matrix Repair in Aortic Aneurysms	10
Prediction of the Effect of the Osteoarthritic Joint Microenvironment on Cartilage Repair	10
A Hybrid Electrospun-Extruded Polydioxanone Suture for Tendon Tissue Regeneration	10
Antithrombotic Revascularization Strategy of Bioengineered Liver Using a Biomimetic Polymer	10
Donor Age and Time in Culture Affect Dermal Fibroblast Contraction in an In Vitro Hydrogel Model	10
Repairing Volumetric Muscle Loss with Commercially Available Hydrogels in an Ovine Model	10
Endochondral Bone Tissue Engineering Using Human Induced Pluripotent Stem Cells	10
Expression of Concern: Cost of Stem Cell-Based Tissue-Engineered Airway Transplants in the United Kingdom: Case Series	9
Program and Abstracts	9
30 Years of Tissue Engineering	9
Composite Spheroid-Laden Bilayer Hydrogel for Engineering Three-Dimensional Osteochondral Tissue	9
Evaluation of Dexamethasone-Eluting Cell-Seeded Constructs in a Preclinical Canine Model of Cartilage Repair	9
Artificial Trachea from Microtissue Engineering and Three-Dimensional Printing for Tracheal Personalized Repair	9
Sodium Nitroprusside Stimulation of Elastic Matrix Regeneration by Aneurysmal Smooth Muscle Cells	9
Macrophages at Low-Inflammatory Status Improved Osteogenesis via Autophagy Regulation	8
Mesenchymal Stem Cell Sheets for Engineering of the Tendon–Bone Interface	8
Mechanical Stimulation Induces Vasa Vasorum Capillary Alignment in a Fibrin-Based Tunica Adventitia	8
Posttranscriptional Modification to Modulate Progenitor Differentiation on Heterotypic Spheroids	8
Amino Acids Enhance the Effects of Dexamethasone on Osteogenesis by Rat Stem Cells	8
Bile Duct Regeneration with an Artificial Bile Duct Made of Gelatin Hydrogel Nonwoven Fabrics	8
Polycaprolactone/β-Tricalcium Phosphate Composite Scaffolds with Advanced Pore Geometries Promote Human Mesenchymal Stromal Cells’ Osteogenic Differentiation	8
TERMIS ‐ AMERICAS Toronto, Ontario, Canada July 10–13, 2022	8
Chondrogenesis of Mesenchymal Stem Cells through Local Release of TGF-β3 from Heparinized Collagen Biofabric	8
Induction of M2 Macrophages by Fibrin Hydrogels Enhances Bone Regeneration	7

LATS1/YAP1 Axis Controls Bone Regeneration on Distraction Osteogenesis by Activating Wnt/β-Catenin	7
Engineered Tissue Graft for Repair of Injured Infraspinatus Rotator Cuff Tendon	7
Interspecies Comparison of Multilayer Mechanical Properties of Synovium Using Atomic Force Microscopy	7
Regeneration of Functional Bladder Using Cell-seeded Amnion and P(LA/CL) Scaffolds	7
Oxidized Low-Density Lipoprotein Decreases the Survival of Bone Marrow Stem Cells via Inhibition of Bcl-2 Expression	7
Scaffold-Free Cartilage Construct from Infrapatellar Fat Pad Stem Cells for Cartilage Restoration	7
Poly (ɛ-Caprolactone-co-l,l-Lactide) Vascular External Sheath Carrying Prednisone for Improving Patency Rate of the Vein Graft	7
Promoting a Cobalt Complex of Qingzhuan Dark Tea Polysaccharides on Fracture Healing in Rats	7
Glycations on Decellularized Muscle Matrix Reduce Muscle Regeneration and Increase Inflammation	7
Correction to: Wharton's Jelly-Mesenchymal Stem Cell-Engineered Conduit for Pediatric Translation in Heart Defect, by Iacobazzi, et al. Tissue Engineering Part A 2021;27(3-4):201–213; doi: 10.1	7
JNK2Gene Silencing for Elastic Matrix Regenerative Repair	7
Intracellular Calcium and Sodium Modulation of Self-Assembled Neocartilage Using Costal Chondrocytes	7
Association with Cationized Gelatin Nanospheres Enhances Mitochondria Uptake and Membrane Potential	7
Development of a Self-Assembled Dermal Substitute from Human Fibroblasts Using Long-term Three-Dimensional Culture	7
Physiologic Doses of Transforming Growth Factor-β Improve the Composition of Engineered Articular Cartilage	7
Call for Special Issue Papers: Special Issue for Prof. James Kirkpatrick in Honor of His Achievements in Tissue Engineering/Regenerative Medicine	7
Effects of Release of TSG-6 from Heparin Hydrogels on Supraspinatus Muscle Regeneration	6
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Tissue Engineering Part A	6
Developing a Functional Osteoarthritis Model Using Human Osteochondral–Synovial Explants	6
Immunomodulatory Strategies for Cartilage Regeneration in Osteoarthritis	6
Biogelx-IKVAV Is An Innovative Human Platelet Lysate-Adipose-Derived Stem Cells Delivery Strategy to Improve Peripheral Nerve Repair	6
Decellularization of Massive Bone Allografts By Perfusion: A New Protocol for Tissue Engineering	6
In Vivo Efficacy of a Novel, Sutureless Coaptation Device for Repairing Peripheral Nerve Defects	6
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells	6
Tissue-Engineered Endothelial Keratoplasty with Controlled Cell Density: Toward Super TEEKs	6
The Effect of Dosing of Stromal Cell-Derived Factor 1 on Anal Sphincter Regeneration	6
Abstract Author Index by abstract number	6
Profiles of Exosomal microRNAs in Joint Cells and Candidate microRNAs for Cartilage Regeneration	6
Human Lung Organoid Culture in Alginate With and Without Matrigel to Model Development and Disease	6
Applications of Tissue-Inducing Biomaterials in Nonosseous Tissues: Evidence Map of Animal Studies	6
Tensile Loaded Tissue-Engineered Human Tendon Constructs Stimulate Myotube Formation	6
A Ready-to-Use Purified Exosome Product for Volumetric Muscle Loss and Functional Recovery	6
Downregulation of p38 MAPK Signaling Pathway Ameliorates Tissue-Engineered Corneal Epithelium	6
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	5
Cryopreservation Alters Tissue Structure and Improves Differentiation of Engineered Skeletal Muscle	5
Effect of Cell Density of a Methacrylic Acid-Based Hydrogel Implant on Embedded Islet Function and Viability	5
Macromolecular Crowding Enhances Matrix Protein Deposition in Tissue-Engineered Vascular Grafts	5
Designing Biomimetic 3D-Printed Osteochondral Scaffolds for Enhanced Load-Bearing Capacity	5
Spontaneous Alignment of Myotubes Through Myogenic Progenitor Cell Migration	5
Tissue-Engineered Nerve Grafts: Material Innovations and Clinical Translation Challenges	5
Amino Acid Uptake Limitations during Human Mesenchymal Stem Cell-Based Chondrogenesis	5
In Vivo Delivery of M0, M1, and M2 Macrophage Subtypes via Genipin-Cross-Linked Collagen Biotextile	5
LINC00687 Regulates PRDX2 Expression in High Glucose-Induced Nonunion after Digital Replantation	5
Schwann Cells Do Not Promote Myogenic Differentiation in the EPI Loop Model	5
Cyclic Tensile Stress Induces Skeletal Muscle Hypertrophy and Myonuclear Accretion in a 3D Model	5
Continuous Low-Intensity Ultrasound Improves Cartilage Repair in Rabbit Model of Subchondral Injury	5
Oxygenation and Temperature Conditioning Alter the Vascular Morphology of Microvascular Constructs	5
Effect of Eucomis autumnalis on the Osteogenic Differentiation of Adipose-Derived Stem Cells	4
Differentiating Engineered Tissue Images and Experimental Factors to Classify Cardiomyocyte Content	4
Exosome Cell Origin Affects In Vitro Markers of Tendon Repair in Ovine Macrophages and Tenocytes	4
ZC3H13 Regulates Ferroptosis to Enhance Osteogenic Differentiation in Osteoporotic BMSCs	4
Stem Cell-Seeded 3D-Printed Scaffolds Combined with Self-Assembling Peptides for Bone Defect Repair	4
Cyclic Stretching Enhances Angiocrine Signals at Liver Bud Stage from Human Pluripotent Stem Cells in Two-Dimensional Culture	4
Call for Special Issue Papers: Bioprinting	4
Applications of Regenerative Tissue-Engineered Scaffolds for Treatment of Spinal Cord Injury	4
Erythrocyte Membrane Coating Alleviate Immune Response and Promoted Adipogenesis in Adipose Matrix	4
Editorial for Special Issue on Machine Learning in Tissue Engineering	4
Bioprinting: Mechanical Stabilization and Reinforcement Strategies in Regenerative Medicine	4
A Novel Injectable Cell-Loaded Hydrogel System for Cartilage Repair: In Vivo and In Vitro Study	4
Abstract Author Indexby abstract number	4
Ultrasound-Targeted Microbubble Destruction Assisted Delivery of Platelet-Rich Plasma-Derived Exosomes Promoting Peripheral Nerve Regeneration	4
Editorial: Modulation of the Immune System to Improve Tissue Regeneration Strategies	4
Abstracts TERMIS EU Freiburg, Germany May 20–23, 2025	4
The Effect of Low-Intensity Pulsed Ultrasound on Temporomandibular Joint Arthritis in Juvenile Rats	4
Abstract Author Indexby abstract number	4
Induction of Cartilage Regeneration by Nanoparticles Loaded with Dentin Matrix Extracted Proteins	4
Electrically Triggered Fluorescein and Dexamethasone Release from Conducting Polymer Hydrogels	4
A Standardized g-Force Allows the Preparation of Similar Platelet-Rich Fibrin Qualities Regardless of Rotor Angle	4
Porcine Acellular Nerve-Derived Hydrogel Improves Outcomes of Direct Muscle Neurotization in Rats	4
Aging Impairs Implant Osseointegration Through a Novel Reactive Oxygen Species-Hypoxia-Inducible Factor 1α/p53 Axis	4
Scaffold-Free Osteochondral Engineering Using Embryonic-Derived Mesenchymal Stem Cell Spheroids	4
Repair of Osteochondral Defect with Acellular Cartilage Matrix and Thermosensitive Hydrogel Scaffold	3
A Chondrosphere-Based Scaffold Free Approach to Manufacture anIn VitroArticular Cartilage Model	3
Abstract Author Index by abstract number	3
Revealing Early Spatial Patterns of Cellular Responsivity in Fiber-Reinforced Microenvironments	3
Liquid Ventilation Reconditions Isolated Rat Lungs Following Ischemia–Reperfusion Injury	3
Selection of Force Sensors for In Situ Measurement of Neotissue Microenvironments	3
Three-Dimensional Cell Printed Lock-Key Structure for Oral Soft and Hard Tissue Regeneration	3
Three-Dimensional Culture Promotes Secretion of Extracellular Matrix Structure Fat Flap with Lipoaspirates in Vitro	3
Metformin Treatment of Macrophages Increases Microvessel Growth in Three-Dimensional Hydrogel Coculture	3

Regenerative Potential of Bone Morphogenetic Protein 7-Engineered Mesenchymal Stem Cells in Ligature-Induced Periodontitis	3
Osteoblast-Mesenchymal Stem Cell Coculture Drives In Vitro Osteogenesis in 3D Bioprinted Periosteum	3
Quality Assessment by Bile Composition in Normothermic Machine Perfusion of Rat Livers	3
Combining a Vascular Bundle and 3D Printed Scaffold with BMP-2 Improves Bone Repair and Angiogenesis	3
7^th TERMIS World Congress Seattle, Washington June 25–28, 2024	3
Abstract Author Indexby abstract number	3
Three-Dimensional Bioprinting of Organoids: Past, Present, and Prospective	3
Dual Role of Ibuprofen and Indomethacin in Promoting Peripheral Nerve Regeneration In Vitro	3
Differentiated and Untreated Juvenile Chondrocyte Sheets Regenerate Cartilage Similarly In Vivo	3
The UCMSC-bFGF/Scaffold System Accelerates the Healing of the Uterine Full-Thickness Injury	3
Acknowledgment of Reviewers 2021	3
Aligned Gelatin Microribbon Scaffolds with Hydroxyapatite Gradient for Engineering the Bone–Tendon Interface	3
Implantation of Human-Induced Pluripotent Stem Cell-Derived Cartilage in Bone Defects of Mice	2
Abstract Author Index by abstract number	2
Osteoclast Incorporation in an In Vitro 3D Model of Endochondral Ossification	2
Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins	2
Cell Therapy by Mesenchymal Stromal Cells Versus Myoblasts in a Pig Model of Urinary Incontinence	2
Cell-Derived Extracellular Matrix Fiber Scaffolds Improve Recovery from Volumetric Muscle Loss	2
From Promise to Practice: Recent Growth in 30 Years of Tissue Engineering Commercialization	2
¹³C Metabolic Flux Analysis in Chondrocytes Reveals a Novel Switch in Metabolic Phenotype	2
Supercritical Carbon Dioxide Decellularization of Porcine Nerve Matrix for Regenerative Medicine	2
Three-Dimensional Printed Design of Antibiotic-Releasing Esophageal Patches for Antimicrobial Activity Prevention	2
Thirtieth Anniversary of Tissue Engineering: A Congratulations and a Few Thoughts	2
Extracellular Matrix Alignment Directs Provisional Matrix Assembly and Three Dimensional Fibrous Tissue Closure	2
Aspects of a Suspended Bioprinting System Affect Cell Viability and Support Bath Properties	2
Organotypic 3D Cellular Models Mimicking the Epithelio-Ectomesenchymal Bilayer During Odontogenesis	2
Depletion of MicroRNA-100-5p Promotes Osteogenesis Via Lysine(K)-Specific Demethylase 6B	2
Reconstruction of Fibrocartilage with Fibrous Alignment of Type I Collagen in Scaffold-Free Manner	2
E2-Loaded Microcapsules and Bone Marrow–Derived Mesenchymal Stem Cells with Injectable Scaffolds for Endometrial Regeneration Application	2
Development of a Three-Dimensional Bioartificial Shoulder Joint Implant Mimetic of Periprosthetic Joint Infection	2
Magnetic and Biocompatible Polyurethane Nanofiber Biomaterial for Tissue Engineering	2
Epigenetic Priming Enhances Chondrogenic Potential of Expanded Chondrocytes	2
Matrix Composition Modulates Vitamin D3's Effects on 3D Collagen Fiber Organization by MCF10A Cells	2
Chitosan Bioceramic Composites for Bone Regeneration: Insights from In Vitro and In Vivo Studies	2
Call for Papers: Special Issue on Modulation of the Immune System to Improve Tissue Regeneration Strategies	2
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves	2
Thirty Years of Tissue Engineering	2
Characterization of Native Extracellular Matrix of Patient-Derived Glioblastoma Multiforme Organoids	2
Acknowledgment of Reviewers 2022	2
Vascularization of Human Acellular Dermal Matrices: A Comparative Study in a Nonhuman Primate Model	2
Biodegradable PHBVHHx-PEG/Collagen Hydrogel Scaffolds for Cartilage Repair	2
Advancing Perfusion Models: Dual-Vessel Ex Vivo Rat Liver Perfusion Based on a Clinical Setup	2
Influence of Scaffold Topography and Culture Duration on Fibroblast Morphology in Tissue Engineering	2
Subcutaneously Transplanted Fresh Cartilage in Allogeneic and Xenogeneic Immunocompetent Mouse	2
Surface Engineering for Dental Implantology: Favoring Tissue Responses Along the Implant	2
Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine	2
3D Printed Platelet-Rich Plasma-Loaded Scaffold with Sustained Cytokine Release for Bone Defect Repair	2
Inhibitory Effects of Combined Bone Morphogenetic Protein 2, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor on Osteoclast Differentiation and Activity	2
Progenitor Cell Sources for 3D Bioprinting of Lymphatic Vessels and Potential Clinical Application	2
Bone Marrow Mobilization and Local Stromal Cell-Derived Factor-1α Delivery Enhances Nascent Supraspinatus Muscle Fiber Growth	2
Macrophage Mechano-Responsiveness Within Three-Dimensional Tissue Matrix upon Mechanotherapy-Associated Strains	2