OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cardiovascular Translational Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum	43
In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure	39
Unlocking the Non-invasive Assessment of Conduit and Reservoir Function in the Aorta	38
Modified Exosomes: a Good Transporter for miRNAs within Stem Cells to Treat Ischemic Heart Disease	35
Morphology Optimization of Leaflet for Surgical Reconstruction of the Aortic Valve: In Vitro Test and Simulation-Based DOE Study	32
Correction to: Evaluation of a Rabbit Model of Vascular Stent Healing: Application of Optical Coherence Tomography	29
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia	24
NO-Donation Increases Visceral Circulation in a Porcine Model of Abdominal Hypertension	23
Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease	23
Could Selective Re-look Angiography Improve the Outcome of Cardiogenic Shock in Patients Under Veno-arterial Extracorporeal Membrane Oxygenator?	23
Validity and Reproducibility of the Six-Minute Stepper Test in Cardiac Patients	22
Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants	22
Mechanical and Geometric Characterization of a Novel 2-Ply Vacuum-Pressed Biological Scaffold Patch Design for Posterior Mitral Valve Reconstruction	21
The Role of Mitophagy in Cardiac Metabolic Remodeling of Heart Failure: Insights of Molecular Mechanisms and Therapeutic Prospects	20
Silencing Survivin: a Key Therapeutic Strategy for Cardiac Hypertrophy	20
Wearables in Cardiovascular Disease	20
Danlou Tablet Protects Against Cardiac Remodeling and Dysfunction after Myocardial Ischemia/Reperfusion Injury through Activating AKT/FoxO3a Pathway	20
Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction	19
The Role of Extracellular Non-coding RNAs in Atherosclerosis	19
PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats	18
Clinical Impact of the Endo-aortic Clamp for Redo Mitral Valve Surgery	18
Modeling the Hemodynamic Impact of Y-incision Aortic Annular Enlargements on Aortic Valve Replacement and Valve-in-Valve Procedures	17
Eosinophil Recovery Time Is Associated with Clinical Outcomes in Patients with Type A Acute Aortic Dissection: a Retrospective Cohort Study	17
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation	16
Translocation of the Mitral Valve in an Acute Large Animal Model	16

RNA Therapies in Cardio-Kidney-Metabolic Syndrome: Advancing Disease Management	16
MSCs-Derived Extracellular Vesicles Carrying miR-212-5p Alleviate Myocardial Infarction-Induced Cardiac Fibrosis via NLRC5/VEGF/TGF-β1/SMAD Axis	15
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation	15
Machine Learning-Driven Identification of Blood-Based Biomarkers and Therapeutic Agents for Personalized Ischemic Stroke Management	15
Trimethylamine N-Oxide Promotes Abdominal Aortic Aneurysm Formation by Aggravating Aortic Smooth Muscle Cell Senescence in Mice	15
The Mechanism Underlying the Regulation of LncRNA-ASLNC18810 Involved in the Abnormal Function of Vascular Endothelial Cell in Atherosclerosis: Its Function as a microRNA (miRNA) Sponge for miR-559	15
Leukocyte Extracellular Vesicles Predict Progression of Systolic Dysfunction in Heart Failure with Mildly Reduced Ejection Fraction (LYCHEE) – A Prospective, Multicentre Cohort Study	14
Magnetic Resonance Imaging for Cerebral Micro-embolizations During Minimally Invasive Mitral Valve Surgery	14
Reply to Correspondence on “Absence of Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents”	14
An Animal Model of Functional Tricuspid Regurgitation by Leaflet Tethering Using Image-Guided Chordal Encircling Snares	14
The Role of the Association Between Serum C-Reactive Protein Levels and Coronary Plaque Macrophage Accumulation in Predicting Clinical Events — Results from the CLIMA Registry	13
The Role of Methylation in Ferroptosis	13
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development	13
The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration	13
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways	13
High-Density Lipoprotein: a Molecule-Modulating Angiogenesis	12
Correction to: CircNCX1: the “Lord of the Ring” in the Heart — Insight into Its Sequence Characteristic, Expression, Molecular Mechanisms, and Clinical Application	12
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity	12
A New Aspect of Penehyclidine Hydrochloride in Alleviating Myocardial Ischemia–Reperfusion Injury: Ferroptosis	12
Impact of Myocardial Fibrosis on Cardiovascular Structure, Function and Functional Status in Heart Failure with Preserved Ejection Fraction	12
Ferrostatin-1 Blunts Right Ventricular Hypertrophy and Dysfunction in Pulmonary Arterial Hypertension by Suppressing the HMOX1/GSH Signaling	11
Platelet microRNA Expression Can Predict Bleeding in HeartMate3 Patients Treated With or Without Aspirin	11
Abdominal Aortic Aneurysm Formation: a Yap’s View	11
A Molecular Perspective on the Intricate Interplay Among Exosomes, Bioenergetic Metabolism, and the Pathogenesis of Diabetic Cardiomyopathy	11
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics	11
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis	10
The Role of ADAM17 in Inflammation-Related Atherosclerosis	10
Study of The Relationship Between Differential Small Molecule Peptides in Peripheral Blood and Arteriosclerosis in Patients with Essential Hypertension	10
Irisin Regulates Cardiac Responses to Exercise in Health and Diseases: a Narrative Review	10
Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome	10
A Novel Dual Latex Balloon Catheter for Temporarily Closing Acute Postinfarction Ventricle Septum Defect (VSD) in a Pig Model	10
From Energy Metabolic Change to Precision Therapy: a Holistic View of Energy Metabolism in Heart Failure	10
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes	10
Cardiac Overexpression of Chil1 Improves Wound Healing to Prevent Cardiac Rupture After Myocardial Infarction	9
Advances in Glycolysis Metabolism of Atherosclerosis	9
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia	9
Fluid Shear Stress Ameliorates Prehypertension-Associated Decline in Endothelium-Reparative Potential of Early Endothelial Progenitor Cells	9
The Role of Angiogenesis and Arteriogenesis in Myocardial Infarction and Coronary Revascularization	9
DDX17: A Potential Target for Heart Failure Therapies	9
Correction to: Mapping Renal Innervations by Renal Nerve Stimulation and Characterizations of Blood Pressure Response Patterns	9
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications	9
Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography	9
The Protective Effect of miR-27-3p on Ischemia-Reperfusion-Induced Myocardial Injury Depends on HIF-1α and Galectin-3	9
CRISPR-Cas9 Targeting PCSK9: A Promising Therapeutic Approach for Atherosclerosis	9
Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk	8
Circulating Extracellular Vesicles Predict Complications after Cardiac Surgery	8
Correction to: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide	8
Intravascular Ultrasound-Based Fractional Flow Reserve for Predicting Prognosis after Percutaneous Coronary Intervention	8
The Effects of ATIR Blocker on the Severity of COVID-19 in Hypertensive Inpatients and Virulence of SARS-CoV-2 in Hypertensive hACE2 Transgenic Mice	8
Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery	8

Correlation Between NLR to Albumin Ratio and 90-day Prognosis After Treatment for Acute Ischemic Stroke	8
TAVI Under Pressure: Intra-balloon Pressure Profiles During Balloon-Expandable TAVR—First Data from a Feasibility Study	8
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction	8
Inhibition of Hsp90 K284 Acetylation Aalleviates Cardiac Injury After Ischemia–Reperfusion Injury	8
Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive?	8
Remote Ischemic Conditioning Mediates Cardio-protection After Myocardial Ischemia/Reperfusion Injury by Reducing 4-HNE Levels and Regulating Autophagy via the ALDH2/SIRT3/HIF1α Signaling Pathway	8
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells	8
Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans	8
Connecting the Dots: Stress Granule and Cardiovascular Diseases	8
Cardiac Metabolism, Reprogramming, and Diseases	7
CNDP2: An Enzyme Linking Metabolism and Cardiovascular Diseases?	7
Weak UVB Irradiation Promotes Macrophage M2 Polarization and Stabilizes Atherosclerosis	7
Past Trends and Future Directions of Cardiac Regenerative Medicine – A Systematic Analysis of Clinical Trial Registries	7
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis	7
Automated Data Transformation and Feature Extraction for Oxygenation-Sensitive Cardiovascular Magnetic Resonance Images	7
Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer	7
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases	7
Identification of Gravida Serum Biomarkers for Noninvasive Prenatal Diagnosis Fetal Congenital Heart Disease	7
Correction to: Computational Fluid Dynamics Support for Fontan Planning in Minutes, Not Hours: The Next Step in Clinical Pre-Interventional Simulations	7
Cardiac Magnetic Resonance-Derived Left Ventricular Mechanical Dispersion Improves Risk Stratification of Hypertrophic Cardiomyopathy and its Correlations with Scar Heterogeneity	7
Normoxemic Extracorporeal Membrane Oxygenation Reduces Infarct Size and Preserves Mitochondrial Integrity in Preclinical Models of Acute Myocardial Infarction	7
Emerging Paradigms in Atherosclerosis: The Impact of LncRNA PSMB8-AS1 on Vascular Inflammation and Plaque Formation	7
Cellular and Extracellular Non-coding RNAs in Cardiac Physiology and Diseases	7
Assessment of Paravalvular Leak Severity and Thrombogenic Potential in Transcatheter Bicuspid Aortic Valve Replacements Using Patient-Specific Computational Modeling	7
Non-Coding RNA-Mediated Gene Regulation in Cardiovascular Disorders: Current Insights and Future Directions	6
Hif-1α/Slit2 Mediates Vascular Smooth Muscle Cell Phenotypic Changes in Restenosis of Bypass Grafts	6
The Effect of Extracellular Vesicles on Thrombosis	6
LncRNA HDAC11-AS1 Suppresses Atherosclerosis by Inhibiting HDAC11-Mediated Adropin Histone Deacetylation	6
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study	6
Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses	6
p16INK4a Aggravated Sepsis-associated Cardiac Injury by Inhibiting the PI3K/AKT Pathway and Inducing Redox Imbalance	6
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension	6
Optimization of Strategy for Modified mRNA Inducing Cardiac-Specific Expression in Mice	6
The Fibrinogen-to-Albumin Ratio Is Associated with Poor Prognosis in Patients with Coronary Artery Disease: Findings from a Large Cohort	6
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis	6
The Role of Regulatory T Cells in Heart Repair After Myocardial Infarction	6
Emerging Roles of Extracellular Non-Coding RNAs in Vascular Diseases	6
Association Between Automated 3D Measurement of Coronary Luminal Narrowing and Risk of Future Myocardial Infarction	6
New Insights into the Genetics of Cardiomyopathies	6
Harnessing Electronic Medical Records in Cardiovascular Clinical Practice and Research	6
Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies	6
Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment	6
Navigating the Regulatory Pathway for Medical Devices—a Conversation with the FDA, Clinicians, Researchers, and Industry Experts	6
The Role of Gut Microbiota and Trimethylamine N-oxide in Cardiovascular Diseases	6
Predictors of Myocardial Ischemia in Patients with Kawasaki Disease: Insights from Patient-Specific Simulations of Coronary Hemodynamics	5
Impaired Endothelial Glycocalyx Predicts Adverse Outcome in Subjects Without Overt Cardiovascular Disease: a 6-Year Follow-up Study	5
The Clinical Significance of miR-139-5p in Acute Coronary Syndrome and its Potential Effect on the Progression of Acute Coronary Syndrome	5
Correction to: A Novel Hemostatic Belt Allowing Ambulation Soon After Atrial Fibrillation Ablation	5
CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b	5
Novel Genetic Variants Associated with Primary Myocardial Fibrosis in Sudden Cardiac Death Victims	5
Roles and Mechanisms of TGR5 in the Modulation of CD4+ T Cell Functions in Myocardial Infarction	5
Clinical Value of Computational Angiography-derived Fractional Flow Reserve in Stable Coronary Artery Disease	5
Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases	5
Predictors of Survival and Favorable Neurologic Outcome in Patients Treated with eCPR: a Systematic Review and Meta-analysis	5
Validation of a Whole Heart Segmentation from Computed Tomography Imaging Using a Deep-Learning Approach	5
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease	5
A Simple Model for Predicting 10-Year Cardiovascular Risk in Middle-Aged to Older Chinese: Guangzhou Biobank Cohort Study	5
Predicting the Success Rate of Elective Percutaneous Coronary Intervention for Prior Failed Chronic Total Occlusion: a Novel Scoring System	5
Potential of Phage Display Antibody Technology for Cardiovascular Disease Immunotherapy	5
Circulating miRNAs Signature as a Predictor of Cachexia in Chronic Heart Failure: Diagnostic and Prognostic Implications	5
Copper Homeostasis and Cuproptosis As Potential Intervention Strategy in Atherosclerosis	5
Correction to: Improving Nocturnal Hypoxemic Burden with Transvenous Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea	5
circCELF1 Inhibits Myocardial Fibrosis by Regulating the Expression of DKK2 Through FTO/m6A and miR-636	5
Senescence-related Genes as Prognostic Markers for STEMI Patients: LASSO Regression-Based Bioinformatics and External Validation	5
Dickkopf1 (Dkk1) Alleviates Vascular Calcification by Regulating the Degradation of Phospholipase D1 (PLD1)	5
FAM3A As a Potential Molecular Target to Regulate Mitochondrial Respiration and ATP Production in Ischemic Heart	5
Single-Dose St. Thomas Versus Custodiol® Cardioplegia for Right Mini-thoracotomy Mitral Valve Surgery	5
miR-16-5p Is a Novel Mediator of Venous Smooth Muscle Phenotypic Switching	5
Deep Learning Model for Coronary Angiography	5
Mitral Valve Translocation: Optimization of Patch Geometry in an Ex Vivo Model of Secondary Mitral Regurgitation	5