OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Cardiovascular Translational Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum	46
In Vitro Mitral Valve Model with Unrestricted Ventricular Access: Using Vacuum to Close the Valve and Enable Static Trans-Mitral Pressure	40
Unlocking the Non-invasive Assessment of Conduit and Reservoir Function in the Aorta	38
Morphology Optimization of Leaflet for Surgical Reconstruction of the Aortic Valve: In Vitro Test and Simulation-Based DOE Study	35
Correction to: Evaluation of a Rabbit Model of Vascular Stent Healing: Application of Optical Coherence Tomography	34
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia	29
Could Selective Re-look Angiography Improve the Outcome of Cardiogenic Shock in Patients Under Veno-arterial Extracorporeal Membrane Oxygenator?	26
Intrapericardial Administration to Achieve Localized and Targeted Treatment for Cardiac Disease	24
NO-Donation Increases Visceral Circulation in a Porcine Model of Abdominal Hypertension	24
Validity and Reproducibility of the Six-Minute Stepper Test in Cardiac Patients	23
Response to Editorial Note: "Epigenetic Control of Cardiomyocyte Necrosis: Targeting ACSS2 to Attenuate Myocardial Ischemia/Reperfusion Injury"	23
Heart Failure with Recovered Ejection Fraction in Patients with Vinculin Loss-of-function Variants	23
Modified Exosomes: a Good Transporter for miRNAs within Stem Cells to Treat Ischemic Heart Disease	23
Optimizing Culotte Technique With Double Kissing Balloon Inflation	22
Mechanical and Geometric Characterization of a Novel 2-Ply Vacuum-Pressed Biological Scaffold Patch Design for Posterior Mitral Valve Reconstruction	21
Angiography-Derived Coronary Flow Reserve for Integrated Assessment of Coronary Physiology	21
Wearables in Cardiovascular Disease	20
The Mechanism Underlying the Regulation of LncRNA-ASLNC18810 Involved in the Abnormal Function of Vascular Endothelial Cell in Atherosclerosis: Its Function as a microRNA (miRNA) Sponge for miR-559	20
MSCs-Derived Extracellular Vesicles Carrying miR-212-5p Alleviate Myocardial Infarction-Induced Cardiac Fibrosis via NLRC5/VEGF/TGF-β1/SMAD Axis	19
The Role of Mitophagy in Cardiac Metabolic Remodeling of Heart Failure: Insights of Molecular Mechanisms and Therapeutic Prospects	19
Danlou Tablet Protects Against Cardiac Remodeling and Dysfunction after Myocardial Ischemia/Reperfusion Injury through Activating AKT/FoxO3a Pathway	19
Harnessing the Plasma Proteome to Mirror Current and Predict Future Cardiac Remodeling After Myocardial Infarction	18
The Role of Extracellular Non-coding RNAs in Atherosclerosis	18
PPARγ Agonist Rosiglitazone and Antagonist GW9662: Antihypertensive Effects on Chronic Intermittent Hypoxia-Induced Hypertension in Rats	17
Clinical Impact of the Endo-aortic Clamp for Redo Mitral Valve Surgery	17

Eosinophil Recovery Time Is Associated with Clinical Outcomes in Patients with Type A Acute Aortic Dissection: a Retrospective Cohort Study	16
Translocation of the Mitral Valve in an Acute Large Animal Model	16
Modeling the Hemodynamic Impact of Y-incision Aortic Annular Enlargements on Aortic Valve Replacement and Valve-in-Valve Procedures	16
RNA Therapies in Cardio-Kidney-Metabolic Syndrome: Advancing Disease Management	15
Machine Learning-Driven Identification of Blood-Based Biomarkers and Therapeutic Agents for Personalized Ischemic Stroke Management	15
High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation	15
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation	15
Magnetic Resonance Imaging for Cerebral Micro-embolizations During Minimally Invasive Mitral Valve Surgery	14
Leukocyte Extracellular Vesicles Predict Progression of Systolic Dysfunction in Heart Failure with Mildly Reduced Ejection Fraction (LYCHEE) – A Prospective, Multicentre Cohort Study	14
An Animal Model of Functional Tricuspid Regurgitation by Leaflet Tethering Using Image-Guided Chordal Encircling Snares	14
Reply to Correspondence on “Absence of Myocardial Involvement after SARS-CoV-2 Vaccination in Asymptomatic Adolescents”	14
A New Aspect of Penehyclidine Hydrochloride in Alleviating Myocardial Ischemia–Reperfusion Injury: Ferroptosis	13
The Role of Methylation in Ferroptosis	13
The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration	13
The Role of the Association Between Serum C-Reactive Protein Levels and Coronary Plaque Macrophage Accumulation in Predicting Clinical Events — Results from the CLIMA Registry	13
Silencing DOCK2 Attenuates Cardiac Fibrosis Following Myocardial Infarction in Mice Via Targeting PI3K/Akt and Wnt/β-Catenin Pathways	12
Trimethylamine N-Oxide Promotes Abdominal Aortic Aneurysm Formation by Aggravating Aortic Smooth Muscle Cell Senescence in Mice	12
Correction to: CircNCX1: the “Lord of the Ring” in the Heart — Insight into Its Sequence Characteristic, Expression, Molecular Mechanisms, and Clinical Application	12
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development	12
Impact of Myocardial Fibrosis on Cardiovascular Structure, Function and Functional Status in Heart Failure with Preserved Ejection Fraction	11
Platelet microRNA Expression Can Predict Bleeding in HeartMate3 Patients Treated With or Without Aspirin	11
Irisin Regulates Cardiac Responses to Exercise in Health and Diseases: a Narrative Review	11
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity	11
Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome	11
A Molecular Perspective on the Intricate Interplay Among Exosomes, Bioenergetic Metabolism, and the Pathogenesis of Diabetic Cardiomyopathy	11
High-Density Lipoprotein: a Molecule-Modulating Angiogenesis	11
The Role of ADAM17 in Inflammation-Related Atherosclerosis	11
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes	10
Chitinase-3-like Protein 1 Reduces the Stability of Atherosclerotic Plaque via Impairing Macrophagic Efferocytosis	10
Ferrostatin-1 Blunts Right Ventricular Hypertrophy and Dysfunction in Pulmonary Arterial Hypertension by Suppressing the HMOX1/GSH Signaling	10
Study of The Relationship Between Differential Small Molecule Peptides in Peripheral Blood and Arteriosclerosis in Patients with Essential Hypertension	10
Extracellular Vesicles as Diagnostic Metrics for Cardiovascular Disease: Where We are and How to Achieve in Clinics	10
Cardiac Overexpression of Chil1 Improves Wound Healing to Prevent Cardiac Rupture After Myocardial Infarction	10
A Novel Dual Latex Balloon Catheter for Temporarily Closing Acute Postinfarction Ventricle Septum Defect (VSD) in a Pig Model	10
Abdominal Aortic Aneurysm Formation: a Yap’s View	10
From Energy Metabolic Change to Precision Therapy: a Holistic View of Energy Metabolism in Heart Failure	9
Fluid Shear Stress Ameliorates Prehypertension-Associated Decline in Endothelium-Reparative Potential of Early Endothelial Progenitor Cells	9
DDX17: A Potential Target for Heart Failure Therapies	9
Advances in Glycolysis Metabolism of Atherosclerosis	9
Analysis of Correlation Between Coronary Heart Disease and Genetic Polymorphism Detected by Gold Magnetic Nanoparticles Chromatography	9
The Protective Effect of miR-27-3p on Ischemia-Reperfusion-Induced Myocardial Injury Depends on HIF-1α and Galectin-3	9
Machine Learning-based Prediction of Temporal Velocity-Informatics (TVI) Variables for Accelerated Characterization of Intracranial Aneurysms’ Rupture Status	9
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications	9
Exosomes Derived from AT2R-Overexpressing BMSC Prevent Restenosis After Carotid Artery Injury by Attenuating the Injury-Induced Neointimal Hyperplasia	9
The Role of Angiogenesis and Arteriogenesis in Myocardial Infarction and Coronary Revascularization	9
Correlation Between NLR to Albumin Ratio and 90-day Prognosis After Treatment for Acute Ischemic Stroke	8
Preclinical Assessment of a Novel Polymer-Free Hybrid Drug Eluting Stent	8
Circulating Extracellular Vesicles Predict Complications after Cardiac Surgery	8
Inhibition of Hsp90 K284 Acetylation Aalleviates Cardiac Injury After Ischemia–Reperfusion Injury	8
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells	8

Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery	8
Targeting Canonical Wnt-signaling Through GSK-3β in Arrhythmogenic Cardiomyopathy: Conservative or Progressive?	8
Single-Cell Sequencing Identifies the Crucial Role of Mitochondrial Fission–Fusion Imbalance in Heart Failure Progression	8
CRISPR-Cas9 Targeting PCSK9: A Promising Therapeutic Approach for Atherosclerosis	8
Correction to: Mapping Renal Innervations by Renal Nerve Stimulation and Characterizations of Blood Pressure Response Patterns	8
Gut Microbiota as Predictive Biomarker for Chronic Heart Failure in Patients with Different Nutritional Risk	8
Remote Ischemic Conditioning Mediates Cardio-protection After Myocardial Ischemia/Reperfusion Injury by Reducing 4-HNE Levels and Regulating Autophagy via the ALDH2/SIRT3/HIF1α Signaling Pathway	8
Correction to: LINC01013 Is a Determinant of Fibroblast Activation and Encodes a Novel Fibroblast-Activating Micropeptide	8
Postconditioning with Lactate-Enriched Blood for Reducing Lethal Reperfusion Injury in Humans	7
Emerging Paradigms in Atherosclerosis: The Impact of LncRNA PSMB8-AS1 on Vascular Inflammation and Plaque Formation	7
Cardiac Metabolism, Reprogramming, and Diseases	7
Intravascular Ultrasound-Based Fractional Flow Reserve for Predicting Prognosis after Percutaneous Coronary Intervention	7
Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction	7
Normoxemic Extracorporeal Membrane Oxygenation Reduces Infarct Size and Preserves Mitochondrial Integrity in Preclinical Models of Acute Myocardial Infarction	7
The Effects of ATIR Blocker on the Severity of COVID-19 in Hypertensive Inpatients and Virulence of SARS-CoV-2 in Hypertensive hACE2 Transgenic Mice	7
Automated Data Transformation and Feature Extraction for Oxygenation-Sensitive Cardiovascular Magnetic Resonance Images	7
CNDP2: An Enzyme Linking Metabolism and Cardiovascular Diseases?	7
TAVI Under Pressure: Intra-balloon Pressure Profiles During Balloon-Expandable TAVR—First Data from a Feasibility Study	7
Chronic Oxidative Stress as a Marker of Long-term Radiation-Induced Cardiovascular Outcomes in Breast Cancer	7
Cardiac Magnetic Resonance-Derived Left Ventricular Mechanical Dispersion Improves Risk Stratification of Hypertrophic Cardiomyopathy and its Correlations with Scar Heterogeneity	7
Connecting the Dots: Stress Granule and Cardiovascular Diseases	7
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases	7
Hif-1α/Slit2 Mediates Vascular Smooth Muscle Cell Phenotypic Changes in Restenosis of Bypass Grafts	6
Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies	6
LncRNA HDAC11-AS1 Suppresses Atherosclerosis by Inhibiting HDAC11-Mediated Adropin Histone Deacetylation	6
Cellular and Extracellular Non-coding RNAs in Cardiac Physiology and Diseases	6
Non-Coding RNA-Mediated Gene Regulation in Cardiovascular Disorders: Current Insights and Future Directions	6
Association Between Automated 3D Measurement of Coronary Luminal Narrowing and Risk of Future Myocardial Infarction	6
Identification of Gravida Serum Biomarkers for Noninvasive Prenatal Diagnosis Fetal Congenital Heart Disease	6
Optimization of Strategy for Modified mRNA Inducing Cardiac-Specific Expression in Mice	6
Exosomal miRNAs: A New Frontier in Cardiovascular Disease Diagnosis and Treatment	6
Plasma Biomarker Screening Based on Proteomic Signature of Patients with Resistant Hypertension	6
Past Trends and Future Directions of Cardiac Regenerative Medicine – A Systematic Analysis of Clinical Trial Registries	6
p16INK4a Aggravated Sepsis-associated Cardiac Injury by Inhibiting the PI3K/AKT Pathway and Inducing Redox Imbalance	6
The Role of Gut Microbiota and Trimethylamine N-oxide in Cardiovascular Diseases	6
New Insights into the Genetics of Cardiomyopathies	6
Harnessing Electronic Medical Records in Cardiovascular Clinical Practice and Research	6
Knockdown of Mmu-circ-0001380 Attenuates Myocardial Ischemia/Reperfusion Injury via Modulating miR-106b-5p/Phlpp2 Axis	6
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis	6
Correction to: Computational Fluid Dynamics Support for Fontan Planning in Minutes, Not Hours: The Next Step in Clinical Pre-Interventional Simulations	6
Assessment of Paravalvular Leak Severity and Thrombogenic Potential in Transcatheter Bicuspid Aortic Valve Replacements Using Patient-Specific Computational Modeling	6
Weak UVB Irradiation Promotes Macrophage M2 Polarization and Stabilizes Atherosclerosis	6
The Effect of Extracellular Vesicles on Thrombosis	5
The Role of Regulatory T Cells in Heart Repair After Myocardial Infarction	5
Correction to: Improving Nocturnal Hypoxemic Burden with Transvenous Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea	5
Inhibition of METTL4: Targeting a Methyltransferase that Alleviates Heart Failure by Modulating Excess N6-Methyladenine in Mitochondrial DNA	5
Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases	5
Predicting the Success Rate of Elective Percutaneous Coronary Intervention for Prior Failed Chronic Total Occlusion: a Novel Scoring System	5
Correction to: A Novel Hemostatic Belt Allowing Ambulation Soon After Atrial Fibrillation Ablation	5
Impaired Endothelial Glycocalyx Predicts Adverse Outcome in Subjects Without Overt Cardiovascular Disease: a 6-Year Follow-up Study	5
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease	5
The Fibrinogen-to-Albumin Ratio Is Associated with Poor Prognosis in Patients with Coronary Artery Disease: Findings from a Large Cohort	5
Navigating the Regulatory Pathway for Medical Devices—a Conversation with the FDA, Clinicians, Researchers, and Industry Experts	5
The Clinical Significance of miR-139-5p in Acute Coronary Syndrome and its Potential Effect on the Progression of Acute Coronary Syndrome	5
Deep Learning Model for Coronary Angiography	5
Circulating miRNAs Signature as a Predictor of Cachexia in Chronic Heart Failure: Diagnostic and Prognostic Implications	5
circCELF1 Inhibits Myocardial Fibrosis by Regulating the Expression of DKK2 Through FTO/m6A and miR-636	5
Single-Dose St. Thomas Versus Custodiol® Cardioplegia for Right Mini-thoracotomy Mitral Valve Surgery	5
Phenotypic and Genetic Factors Associated with Absence of Cardiomyopathy Symptoms in PLN:c.40_42delAGA Carriers	5
Dickkopf1 (Dkk1) Alleviates Vascular Calcification by Regulating the Degradation of Phospholipase D1 (PLD1)	5
Predictors of Survival and Favorable Neurologic Outcome in Patients Treated with eCPR: a Systematic Review and Meta-analysis	5
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study	5
Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses	5
Metabolomic Profiling for Predicting Coronary Artery Aneurysms and IVIG Resistance in Kawasaki Disease- An Exploratory Study	5
Emerging Roles of Extracellular Non-Coding RNAs in Vascular Diseases	5
Copper Homeostasis and Cuproptosis As Potential Intervention Strategy in Atherosclerosis	5
miR-16-5p Is a Novel Mediator of Venous Smooth Muscle Phenotypic Switching	5
Mitral Valve Translocation: Optimization of Patch Geometry in an Ex Vivo Model of Secondary Mitral Regurgitation	5
FAM3A As a Potential Molecular Target to Regulate Mitochondrial Respiration and ATP Production in Ischemic Heart	5
Predictors of Myocardial Ischemia in Patients with Kawasaki Disease: Insights from Patient-Specific Simulations of Coronary Hemodynamics	5
CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b	5
Senescence-related Genes as Prognostic Markers for STEMI Patients: LASSO Regression-Based Bioinformatics and External Validation	5