OOIR: Observatory of International Research

Papers

(The TQCC of Cancer Prevention Research is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Germline Pathogenic Variants in the Ataxia Telangiectasia Mutated (ATM) Gene are Associated with High and Moderate Risks for Multiple Cancers	70
Disparities in Cancer Prevention in the COVID-19 Era	52
Mitochondria as a Novel Target for Cancer Chemoprevention: Emergence of Mitochondrial-targeting Agents	46
Association of Aspirin, Metformin, and Statin Use with Gastric Cancer Incidence and Mortality: A Nationwide Cohort Study	35
Dietary Advanced Glycation End-products (AGE) and Risk of Breast Cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO)	29
National Survey of Patient Factors Associated with Colorectal Cancer Screening Preferences	28
Cancer Prevention with Resistant Starch in Lynch Syndrome Patients in the CAPP2-Randomized Placebo Controlled Trial: Planned 10-Year Follow-up	27
Weight Loss During Intrauterine Progestin Treatment for Obesity-associated Atypical Hyperplasia and Early-Stage Cancer of The Endometrium	27
Specificity of the Multi-Target Stool DNA Test for Colorectal Cancer Screening in Average-Risk 45–49 Year-Olds: A Cross-Sectional Study	26
Phenotypic Differences in Juvenile Polyposis Syndrome With or Without a Disease-causing SMAD4/BMPR1A Variant	26
Effect of Low-dose and Standard-dose Aspirin on PGE2 Biosynthesis Among Individuals with Colorectal Adenomas: A Randomized Clinical Trial	25
Epigallocatechin Gallate Induces Hepatic Stellate Cell Senescence and Attenuates Development of Hepatocellular Carcinoma	25
External Validation of Risk Prediction Models Incorporating Common Genetic Variants for Incident Colorectal Cancer Using UK Biobank	24
Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis	23
Upper Endoscopic Surveillance in Lynch Syndrome Detects Gastric and Duodenal Adenocarcinomas	22
Population-based Genetic Testing for Precision Prevention	21
The COX-2–PGE2 Pathway Promotes Tumor Evasion in Colorectal Adenomas	21
The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis	20
Inflammatory and Insulinemic Dietary Patterns: Influence on Circulating Biomarkers and Prostate Cancer Risk	19
A Comprehensive Review and Perspective on Anticancer Mechanisms of Withaferin A in Breast Cancer	19
Maternal Epigenetic Regulation Contributes to Prevention of Estrogen Receptor–negative Mammary Cancer with Broccoli Sprout Consumption	18
Cancer Risk in Normal Weight Individuals with Metabolic Obesity: A Narrative Review	18
Oral Microbiome Profiling in Smokers with and without Head and Neck Cancer Reveals Variations Between Health and Disease	18
Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial	18
Multi-omics Analysis Reveals Adipose–tumor Crosstalk in Patients with Colorectal Cancer	18

Immune Checkpoint Inhibition is Safe and Effective for Liver Cancer Prevention in a Mouse Model of Hepatocellular Carcinoma	18
The Performance of Colorectal Cancer Screening in Brazil: The First Two Years of the Implementation Program in Barretos Cancer Hospital	18
Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of Oral Squamous Cell Carcinoma	17
Oral Squamous Cell Carcinoma Associated with Precursor Lesions	17
Randomized Phase IIB Trial of the Lignan Secoisolariciresinol Diglucoside in Premenopausal Women at Increased Risk for Development of Breast Cancer	16
COVID-19, Cancer Care and Prevention	16
Molecular Mechanism for Breast Cancer Incidence in the Women's Health Initiative	16
Plasma miRNA Biomarkers in Limited Volume Samples for Detection of Early-stage Pancreatic Cancer	16
Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE Study	16
Randomized Phase II Trial of Polyphenon E versus Placebo in Patients at High Risk of Recurrent Colonic Neoplasia	15
A Proposal to Improve the Early Diagnosis of Symptomatic Cancers in the United States	15
Reasons for Not Attending Cervical Cancer Screening and Associated Factors in Rural Ethiopia	15
Reversing the Genomic, Epigenetic, and Triple-Negative Breast Cancer–Enhancing Effects of Obesity	15
Stakeholder Perspectives on Overcoming Barriers to Cascade Testing in Lynch Syndrome: A Qualitative Study	14
Cost Effectiveness of Whole Population BRCA Genetic Screening for Cancer Prevention in Israel	14
An Integrated Approach for Preventing Oral Cavity and Oropharyngeal Cancers: Two Etiologies with Distinct and Shared Mechanisms of Carcinogenesis	14
Urgent Need for Novel Investigations of Treatments to Quit E-cigarettes: Findings from a Systematic Review	14
Inhibition of miR-21 Regulates Mutant KRAS Effector Pathways and Intercepts Pancreatic Ductal Adenocarcinoma Development	14
THBS2/CA19-9 Detecting Pancreatic Ductal Adenocarcinoma at Diagnosis Underperforms in Prediagnostic Detection: Implications for Biomarker Advancement	13
Optimization of Erlotinib Plus Sulindac Dosing Regimens for Intestinal Cancer Prevention in an Apc-Mutant Model of Familial Adenomatous Polyposis (FAP)	13
Adiposity Change Over the Life Course and Mammographic Breast Density in Postmenopausal Women	13
Epigenome, Transcriptome, and Protection by Sulforaphane at Different Stages of UVB-Induced Skin Carcinogenesis	13
Periodontal Disease, Tooth Loss, and Risk of Serrated Polyps and Conventional Adenomas	13
Effects of Adiposity and Exercise on Breast Tissue and Systemic Metabo-Inflammatory Factors in Women at High Risk or Diagnosed with Breast Cancer	13
Plasma and Urine Metabolite Profiles Impacted by Increased Dietary Navy Bean Intake in Colorectal Cancer Survivors: A Randomized-Controlled Trial	13
Local Anti–PD-1 Delivery Prevents Progression of Premalignant Lesions in a 4NQO-Oral Carcinogenesis Mouse Model	13
Targeting the Cholecystokinin Receptor: A Novel Approach for Treatment and Prevention of Hepatocellular Cancer	13
Upper Gastrointestinal Cancer in China: Spatial Epidemiologic Evidence from Screening Areas	12
“Rescue” of Nonparticipants in Colorectal Cancer Screening: A Randomized Controlled Trial of Three Noninvasive Test Options	12
The Acceptability and Preference of Vaginal Self-sampling for Human Papillomavirus (HPV) Testing among a Multi-ethnic Asian Female Population	12
Inflammation Modulation by Vitamin D and Calcium in the Morphologically Normal Colorectal Mucosa of Patients with Colorectal Adenoma in a Clinical Trial	12
Diet-Associated Inflammation Modulates Inflammation and WNT Signaling in the Rectal Mucosa, and the Response to Supplementation with Dietary Fiber	12
Impact of Personalized Genetic Breast Cancer Risk Estimation With Polygenic Risk Scores on Preventive Endocrine Therapy Intention and Uptake	12
Cost Effectiveness of Lung Cancer Screening With Low-Dose CT in Heavy Smokers in China	12
Analysis of the Transcriptome: Regulation of Cancer Stemness in Breast Ductal Carcinoma In Situ by Vitamin D Compounds	12
Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids	12
Impact of Social Support on Colorectal Cancer Screening among Adult Hispanics/Latinos: A Randomized Community-based Study in Central Pennsylvania	11
Breast-Specific Molecular Clocks Comprised ofELF5Expression and Promoter Methylation Identify Individuals Susceptible to Cancer Initiation	11
Changes in Dietary Inflammatory Index Patterns with Weight Loss in Women: A Randomized Controlled Trial	11
HIST1H2BB and MAGI2 Methylation and Somatic Mutations as Precision Medicine Biomarkers for Diagnosis and Prognosis of High-grade Serous Ovarian Cancer	11
Epigenetics/Epigenomics and Prevention of Early Stages of Cancer by Isothiocyanates	10
COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes	10
A Randomized Controlled Trial on Efficacy of Surgical Excision of Nondysplastic Leukoplakia to Prevent Oral Cancer	10
Leucoselect Phytosome Modulates Serum Eicosapentaenoic Acid, Docosahexaenoic Acid, and Prostaglandin E3 in a Phase I Lung Cancer Chemoprevention Study	10
Immune Responses and Risk of Triple-negative Breast Cancer: Implications for Higher Rates among African American Women	10
PROgesterone Therapy for Endometrial Cancer Prevention in Obese Women (PROTEC) Trial: A Feasibility Study	10
Germline Cancer Susceptibility Gene Testing in Unselected Patients with Hepatobiliary Cancers: A Multi-Center Prospective Study	10
Prevention of Skin Carcinogenesis by the Non-β-blocking R-carvedilol Enantiomer	10
A Systematic Review on Cost-effectiveness Studies Evaluating Ovarian Cancer Early Detection and Prevention Strategies	10
The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer	10

The Effect of Metformin in Treatment of Adenomas in Patients with Familial Adenomatous Polyposis	10
Genome-wide Association Analysis of Proinflammatory Cytokines and Gene–lifestyle Interaction for Invasive Breast Cancer Risk: The WHI dbGaP Study	10
Dietary Pterostilbene for MTA1-Targeted Interception in High-Risk Premalignant Prostate Cancer	9
Impact of Patient Adherence to Stool-Based Colorectal Cancer Screening and Colonoscopy Following a Positive Test on Clinical Outcomes	9
Breast Cancer Risk and Use of Nonsteroidal Anti-inflammatory Agents After a Benign Breast Biopsy	9
Prediction Models for Gastric Cancer Risk in the General Population: A Systematic Review	9
Suppression of Colon Tumorigenesis in MutantApcMice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin	9
Stress-induced Norepinephrine Downregulates CCL2 in Macrophages to Suppress Tumor Growth in a Model of Malignant Melanoma	9
Effect of Antibiotics on Gut and Vaginal Microbiomes Associated with Cervical Cancer Development in Mice	9
Colonoscopy Findings in FIT+ and mt-sDNA+ Patients versus in Colonoscopy-only Patients: New Hampshire Colonoscopy Registry Data	9
Risk of Skin Cancer Associated with Metformin Use: A Meta-Analysis of Randomized Controlled Trials and Observational Studies	9
Oral Health and Risk of Upper Gastrointestinal Cancers in a Large Prospective Study from a High-risk Region: Golestan Cohort Study	9
The Impact of One-week Dietary Supplementation with Kava on Biomarkers of Tobacco Use and Nitrosamine-based Carcinogenesis Risk among Active Smokers	9
Estimating the Screening-Eligible Population Size, Ages 45–74, at Average Risk to Develop Colorectal Cancer in the United States	9
Sleep Characteristics and Risk of Ovarian Cancer Among Postmenopausal Women	8
Noxious Combination of Tobacco Smoke Nitrosamines with Bile, Deoxycholic Acid, Promotes Hypopharyngeal Squamous Cell Carcinoma, via NFκB, In Vivo	8
Association of Common Use Pharmaceuticals in Reducing Risk of Esophageal Adenocarcinoma: A SEER–Medicare Analysis	8
Statin Exposure and Pancreatic Cancer Incidence: A Japanese Regional Population-Based Cohort Study, the Shizuoka Study	8
Preventive Anti-inflammatory Diet to Reduce Gastrointestinal Inflammation in Familial Adenomatous Polyposis Patients: A Prospective Pilot Study	8
Bilateral Salpingo-oophorectomy and Breast Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Assessing the Evidence	8
A Digital Storytelling Intervention for Vietnamese American Mothers to Promote Their Children's HPV Vaccination	8
Uptake and Predictors of Opportunistic Salpingectomy for Ovarian Cancer Risk Reduction in the United States	8
Oral Cancer Risk Assessment for Different Types of Smokeless Tobacco Products Sold Worldwide: A Review of Reviews and Meta-analyses	8
Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer	8
Intranasal Iloprost Prevents Tumors in a Murine Lung Carcinogenesis Model	7
Breast Cancer Chemoprevention: Use and Views of Australian Women and Their Clinicians	7
The Influence of Vitamin D on Mammographic Density: Results from CALGB 70806 (Alliance) a Randomized Clinical Trial	7
The Gut Microbiota Impact Cancer Etiology through “Phase IV Metabolism” of Xenobiotics and Endobiotics	7
HER2-Overexpressing Ductal Carcinoma In Situ Associated with Increased Risk of Ipsilateral Invasive Recurrence, Receptor Discordance with Recurrence	7
Role of Prostaglandin E2 in the Progression of Gastrointestinal Cancer	7
Association Between Aspirin Use and Gastric Adenocarcinoma: A Prospective Cohort Study	7
BRIP1, a Gene Potentially Implicated in Familial Colorectal Cancer Type X	7
Saliva and Lung Microbiome Associations with Electronic Cigarette Use and Smoking	7
Adiposity, Adulthood Weight Change, and Risk of Incident Hepatocellular Carcinoma	7
The Chasm We Must Cross in Japan for Re-promotion of the HPV Vaccine	7
Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer	7
A Novel Biomarker Panel for the Early Detection and Risk Assessment of Hepatocellular Carcinoma in Patients with Cirrhosis	7
Blood Supply of Early Lung Adenocarcinomas in Mice and the Tumor-supplying Vessel Relationship: A Micro-CT Angiography Study	7
Hunger Training as a Self-regulation Strategy in a Comprehensive Weight Loss Program for Breast Cancer Prevention: A Randomized Feasibility Study	7
The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane	7
Physical Activity and Risk of Hepatocellular Carcinoma Among U.S. Men and Women	6
Combination of Sulindac and Bexarotene for Prevention of Intestinal Carcinogenesis in Familial Adenomatous Polyposis	6
Long-Term Glucocorticoid Use and Cancer Risk: A Population-Based Cohort Study in South Korea	6
Single-cell RNA Sequencing Reveals How the Aryl Hydrocarbon Receptor Shapes Cellular Differentiation Potency in the Mouse Colon	6
Randomized Controlled Trial of the Gastrin/CCK2 Receptor Antagonist Netazepide in Patients with Barrett's Esophagus	6
The Association Between Periodontal Disease and Breast Cancer in a Prospective Cohort Study	6
Sociocultural Factors, Access to Healthcare, and Lifestyle: Multifactorial Indicators in Association with Colorectal Cancer Risk	6
Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial	6
Primary Care Provider Beliefs and Recommendations About Colorectal Cancer Screening in Four Healthcare Systems	6
Association of IgG Glycosylation and Esophageal Precancerosis Beyond Inflammation	6
Mitotic Spindle Apparatus Abnormalities in Chronic Obstructive Pulmonary Disease Cells: A Potential Pathway to Lung Cancer	6
Age at Initiation and Frequency of Screening to Prevent Esophageal Squamous Cell Carcinoma in High-risk Regions: an Economic Evaluation	6
Preventing Cervical Cancer Globally: Are We Making Progress?	6
Metabolomics Analysis of Aspirin's Effects in Human Colon Tissue and Associations with Adenoma Risk	6
Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey	6
Intercepting Endometrial Cancer: Opportunities to Expand Access Using New Technology	6
Participatory Design of a Personalized Genetic Risk Tool to Promote Behavioral Health	6
Aspirin and the Risk of Colorectal Cancer According to Genetic Susceptibility among Older Individuals	6
A Pooled Analysis to Compare the Clinical Characteristics of Human Papillomavirus–positive and -Negative Cervical Precancers	6
Phase I Trial of Encapsulated Rapamycin in Patients with Prostate Cancer Under Active Surveillance to Prevent Progression	6
Catchment Areas, Community Outreach and Engagement Revisited: The 2021 Guidelines for Cancer Center Support Grants from the National Cancer Institute	6
Circulating 27-hydroxycholesterol and Risk of Colorectal Adenomas and Serrated Polyps	6