OOIR: Observatory of International Research

Papers

(The TQCC of Oxidative Medicine and Cellular Longevity is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Effect of Administration of an Equal Dose of Selected Dietary Chemicals on Nrf2 Nuclear Translocation in the Mouse Liver	64
Retracted: lncRNA260 siRNA Accelerates M2 Macrophage Polarization and Alleviates Oxidative Stress via Inhibiting IL28RA	43
Retracted: Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1α and Increased Levels of Reactive Oxygen Species	42
Retracted: Natural Products for Neurodegeneration: Regulating Neurotrophic Signals	41
Retracted: Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice	37
Platelets Facilitate Wound Healing by Mitochondrial Transfer and Reducing Oxidative Stress in Endothelial Cells	35
Retracted: Epicardial Adipose Tissue Volume Is Associated with High Risk Plaque Profiles in Suspect CAD Patients	35
Autophagy and Its Lineage-Specific Roles in the Hematopoietic System	30
The Modulatory Effect of an Ethanolic Extract of Anredera cordifolia (Ten.) on the Proliferation and Migration of Hyperglycemic Fibroblasts in an In Vitro Diabetic Wound Model	30
Curcumin Induces Ferroptosis in Follicular Thyroid Cancer by Upregulating HO-1 Expression	26
Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3	26
Exosomes from Adipose-Derived Stem Cells Alleviate Dexamethasone-Induced Bone Loss by Regulating the Nrf2/HO-1 Axis	25
Increased Iron Levels and Oxidative Stress Mediate Age-Related Impairments in Male and Female Drosophila melanogaster	25
EXPRESSION OF CONCERN: Neuroprotective Effect of Tea Polyphenols on Oxyhemoglobin Induced Subarachnoid Hemorrhage in Mice	25
Insights into Photobiomodulation and Oxidative Stress: Physiological, Pathological, and Therapeutic Impact	24
	24
Retracted: Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential	24
RETRACTION: Protocatechuic Acid Prevents oxLDL‐Induced Apoptosis by Activating JNK/Nrf2 Survival Signals in Macrophages	23
Retracted: Ginsenoside Rg1 Ameliorates Acute Renal Ischemia/Reperfusion Injury via Upregulating AMPKα1 Expression	23
RRP Regulates Autophagy through the AMPK Pathway to Alleviate the Effect of Cell Senescence on Atherosclerosis	23
Neuroprotective Effects of Cannabispirenone A against NMDA-Induced Excitotoxicity in Differentiated N2a Cells	23
Retracted: Leukemia Inhibitory Factor Facilitates Self-Renewal and Differentiation and Attenuates Oxidative Stress of BMSCs by Activating PI3K/AKT Signaling	23
Retracted: Novel Insights into the Molecular Features and Regulatory Mechanisms of Mitochondrial Dynamic Disorder in the Pathogenesis of Cardiovascular Disease	23
Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway	22
Correction to “Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15‐Lipoxygenase‐1‐Mediated Microglia and Endothelial Cell Ferroptosis”	22

Identification of Gene Signature-Related Oxidative Stress for Predicting Prognosis of Colorectal Cancer	22
Detecting Glutathione and Related Antioxidants as Biomarkers in Patient Breast Tumor Tissues: An Update in the Age of Metabolomics	22
RETRACTION: Dietary Valine Ameliorated Gut Health and Accelerated the Development of Nonalcoholic Fatty Liver Disease of Laying Hens	21
Olive Leaves Extract and Oleuropein Improve Insulin Sensitivity in 3T3-L1 Cells and in High-Fat Diet-Treated Rats via PI3K/AkT Signaling Pathway	19
Yiyi Fuzi Baijiang Powder Alleviates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats via Inhibiting the TLR4/NF-κB/NLRP3 Inflammasome Signaling Pathway to Repair the Intestinal Epithelial Ba	19
RETRACTION: Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti‐Inflammatory, and Antiapoptotic Properties	19
Retracted: Automatic Detection of Epilepsy Based on Entropy Feature Fusion and Convolutional Neural Network	18
Retracted: PCBP2 Reduced Oxidative Stress-Induced Apoptosis in Glioma through cGAS/STING Pathway by METTL3-Mediated m6A Modification	18
Retracted: miR-494-3p Promotes Erastin-Induced Ferroptosis by Targeting REST to Activate the Interplay between SP1 and ACSL4 in Parkinson’s Disease	18
Retracted: Antiviral Activity of Plantago asiatica Polysaccharide against Pseudorabies Virus In Vitro	18
Reciprocal REGγ-Nrf2 Regulation Promotes Long Period ROS Scavenging in Oxidative Stress-Induced Cell Aging	18
Retracted: DSC2 Suppresses the Metastasis of Gastric Cancer through Inhibiting the BRD4/Snail Signaling Pathway and the Transcriptional Activity of β -Ca	17
Targeting NRF2 With Isoeugenol: A Promising Small Molecule for Neurodegenerative, Metabolic, and Chronic Inflammatory Disorders	17
Chitosan Nanoparticles Alleviated the Adverse Effects of Sildenafil on the Oxidative Stress Markers and Antioxidant Enzyme Activities in Rats	17
Retracted: Protective Effects of Amauroderma rugosum on Doxorubicin-Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunctio	17
RETRACTION: Overexpression of hsa_circ_0061817 Can Inhibit the Proliferation and Invasion of Lung Cancer Cells Based on Active Compounds	17
RETRACTION: Study on the Multitarget Synergistic Effects of Kai‐Xin‐San against Alzheimer’s Disease Based on Systems Biology	16
Retracted: Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis	16
Retracted: Pharmacological Properties of Bergapten: Mechanistic and Therapeutic Aspects	16
Retracted: DNA Topoisomerase II- α Regulated by miR-22-5p Promotes Hepatocellular Carcinoma Invasion and Migration through the Hippo Pathway	16
Retracted: Identification of HIBCH as a Fatty Acid Metabolism-Related Biomarker in Aortic Valve Calcification Using Bioinformatics	15
Corrigendum to “Clinical Relevance and Tumor Growth Suppression of Mitochondrial ROS Regulators Along NADH:Ubiquinone Oxidoreductase Subunit B3 in Thyroid Cancer”	15
Investigation of the Effects of Glabridin on the Proliferation, Apoptosis, and Migration of the Human Colon Cancer Cell Lines SW480 and SW620 and Its Mechanism Based on Reverse Virtual Screening and P	15
Retracted: CDC20 May Serve as a Potential Biomarker-Based Risk Score System in Predicting the Prognosis of Patients with Hepatocellular Carcinoma	15
The Combined Effect of Green Tea, Saffron, Resveratrol, and Citicoline against Neurodegeneration Induced by Oxidative Stress in an In Vitro Model of Cognitive Decline	15
Retracted: Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice	14
The Molecular Blueprint for Chronic Obstructive Pulmonary Disease (COPD): A New Paradigm for Diagnosis and Therapeutics	14
Retracted: Fibroblasts in Scar Formation: Biology and Clinical Translation	14
Retracted: Composite Dietary Antioxidant Index and Plasma Levels of Soluble Klotho: Insights from NHANES	14
Retracted: Oral Administration of Gintonin Protects the Brains of Mice against A β -Induced Alzheimer Disease Pathology: Antioxidant and Anti-Inflammator	14
Role of Gut Microbiota and Oxidative Stress in the Progression of Transplant-Related Complications following Hematopoietic Stem Cell Transplantation	14
Retracted: Irisin Attenuates Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in the H9C2 Cellular Model of Septic Cardiomyopathy through Augmenting Fundc1-Dependent Mitophagy	13
Investigation of Anti-Inflammatory Properties, Phytochemical Constituents, Antioxidant, and Antimicrobial Potentials of the Whole Plant Ethanolic Extract of Achillea santolinoides subsp. wilhelmsii (K	13
A Novel Scientometrics Research on the Interaction between Oxidative Stress and Hematopoietic Stem Cell Transplantation Complications: From Graft-versus-Host Disease to Sepsis	13
Changes in the Proteome of the Circle of Willis during Aging Reveal Signatures of Vascular Disease	13
The Reactive Oxygen Species Scavenger N‐Acetyl‐L‐Cysteine Reduces Storage‐Dependent Decline in Integrin α _IIb β	13
Premorbid Use of Beta-Blockers or Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers in Patients with Acute Ischemic Stroke	13
Identification of Cuproptosis-Related Genes in Nonalcoholic Fatty Liver Disease	13
Retracted: Circular RNA hsa_circ_0002360 Promotes Proliferation and Invasion and Inhibits Oxidative Stress in Gastric Cancer by Sponging miR-629-3p and Regulating the PDLIM4 Expression	12
Retracted: Glymphatic System: Emerging Therapeutic Target for Neurological Diseases	12
Corrigendum to “MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer’s Disease”	12
Retracted: Analysis and Validation of Differentially Expressed Ferroptosis-Related Genes in Regorafenib-Induced Cardiotoxicity	12
Retracted: Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti-inflammatory Mechanism	12
Retracted: Targeted Diagnosis, Therapeutic Monitoring, and Assessment of Atherosclerosis Based on Mesoporous Silica Nanoparticles Coated with cRGD-Platelets	12
Correction to “Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome”	11
Retracted: Inhibition of Oxidative Stress: An Important Molecular Mechanism of Chinese Herbal Medicine (Astragalus membranaceus, Carthamus tinctorius L., Radix Salvia Miltiorrhizae, etc.) in the Treat	11
Correction to “The Combination of Individual Herb of Mi‐Jian‐Chang‐Pu Formula Exerts a Synergistic Effect in the Treatment of Ischemic Stroke in Rats”	11
Retracted: The Risk Model Based on the Three Oxidative Stress-Related Genes Evaluates the Prognosis of LAC Patients	11
Retracted: Single-Cell Transcriptional Profiling Reveals Low-Level Tragus Stimulation Improves Sepsis-Induced Myocardial Dysfunction by Promoting M2 Macrophage Polarization	11
Retracted: Melatonin Attenuates Cardiac Ischemia-Reperfusion Injury through Modulation of IP3R-Mediated Mitochondria-ER Contact	11

RETRACTION: Chidamide Inhibits Glioma Cells by Increasing Oxidative Stress via the miRNA‐338‐5p Regulation of Hedgehog Signaling	10
The Role of Vitamins in Spinal Cord Injury: Mechanisms and Benefits	10
Baicalin Inhibits Airway Smooth Muscle Cells Proliferation through the RAS Signaling Pathway in Murine Asthmatic Airway Remodeling Model	10
Ferulic Acid Attenuates Seizure Severity and Enhances Valproate and Carbamazepine Seizure Preventing Efficacy by Regulating Hippocampal Interleukin‐1β Level and Antioxidant Capacity in Mice	10
LINC01278 Induces Autophagy to Inhibit Tumour Progression by Suppressing the mTOR Signalling Pathway	10
Repurposing Dihydroartemisinin to Combat Oral Squamous Cell Carcinoma, Associated with Mitochondrial Dysfunction and Oxidative Stress	10
C1QC, VSIG4, and CFD as Potential Peripheral Blood Biomarkers in Atrial Fibrillation-Related Cardioembolic Stroke	10
PW06 Triggered Fas-FADD to Induce Apoptotic Cell Death In Human Pancreatic Carcinoma MIA PaCa-2 Cells through the Activation of the Caspase-Mediated Pathway	10
RETRACTION: Sesamin Enhances Nrf2‐Mediated Protective Defense against Oxidative Stress and Inflammation in Colitis via AKT and ERK Activation	10
RETRACTION: TLR4 Modulates Senescence and Paracrine Action in Placental Mesenchymal Stem Cells via Inhibiting Hedgehog Signaling Pathway in Preeclampsia	9
Punica granatum L. Polyphenolic Extract as an Antioxidant to Prevent Kidney Injury in Metabolic Syndrome Rats	9
Retracted: Hsp72-Based Effect and Mechanism of Microwave Radiation-Induced Cardiac Injury in Rats	9
Calreticulin Expression Controls Cellular Redox, Stemness, and Radiosensitivity to Function as a Novel Adjuvant for Radiotherapy in Neuroblastoma	9
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition	9
Retracted: Mitochondrial Dysfunction and Cardiovascular Disease: Pathophysiology and Emerging Therapies	9
Oxidative Stress Response Biomarkers of Ovarian Cancer Based on Single-Cell and Bulk RNA Sequencing	9
Enriched Environment Attenuates Ferroptosis after Cerebral Ischemia/Reperfusion Injury via the HIF-1α-ACSL4 Pathway	9
Coadministration of Monophosphoryl Lipid and Curcumin Modulates Neuroprotective Effects in LPS Stimulated Rat Primary Microglial Cells	9
Retracted: miR-124-3p Delivered Using Exosomes Attenuates the Keratinocyte Response to IL-17A Stimulation in Psoriasis	9
Retracted: Provisional Decision-Making for Perioperative Blood Pressure Management: A Narrative Review	9
Retracted: Distinctive Metabolism-Associated Gene Clusters That Are Also Prognostic in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma	8
Metabolomics Profiling of Age-Associated Metabolites in Malay Population	8
Corrigendum to “Abatacept: A Promising Repurposed Solution for Myocardial Infarction‐Induced Inflammation in Rat Models”	8
Exercise Stress Testing Enhances Plasma Protein Carbonyl Levels in Patients With Asymptomatic Moderate‐to‐Severe Aortic Stenosis	8
Retracted: Breast Cancer Exosome-Derived miR-425-5p Induces Cancer-Associated Fibroblast-Like Properties in Human Mammary Fibroblasts by TGF β 1/ROS Sign	8
Retracted: Allicin Inhibits Osteosarcoma Growth by Promoting Oxidative Stress and Autophagy via the Inactivation of the lncRNA MALAT1-miR-376a-Wnt/ β -Ca	8
Caffeine, MitoQ, and GABA Prophylaxis of Mitochondrial Dysfunction Induced in Human Pulmonary Cells by Normobaric–Hyperoxia and Hyperbaric–Hyperoxia	8
Suppression of Paclitaxel‐Induced Neuropathy and Ovarian Tumor Growth by Mn Porphyrin, MnTnBuOE‐2‐PyP ⁵⁺ (BMX‐001)	8
Tabernaemontana stapfiana Britten (Apocynaceae) Stem Bark Prevents Alcl ₃ ‐Induced Cognitive Disability: Antioxidant and A	8
Retracted: Importance of Gedunin in Antagonizing Rheumatoid Arthritis via Activating the Nrf2/ARE Signaling	8
EXPRESSION OF CONCERN: Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats	8
Correction to “Qishen Granule Protects against Doxorubicin‐Induced Cardiotoxicity by Coordinating MDM2‐p53‐Mediated Mitophagy and Mitochondrial Biogenesis”	8
High-Intensity Interval Training Minimizes the Deleterious Effects of Arterial Hypertension on the Urinary Bladder of Spontaneously Hypertensive Rats	8
Retracted: Verification of Ferroptosis Subcluster-Associated Genes Related to Osteosarcoma and Exploration of Immune Targeted Therapy	7
Retracted: Rocaglamide Prolonged Allograft Survival by Inhibiting Differentiation of Th1/Th17 Cells in Cardiac Transplantation	7
Retracted: GNAI2 Is a Risk Factor for Gastric Cancer: Study of Tumor Microenvironment (TME) and Establishment of Immune Risk Score (IRS)	7
Retracted: ZFP36 Inhibits Tumor Progression of Human Prostate Cancer by Targeting CDK6 and Oxidative Stress	7
Retracted: Identification of Nine M6A-Related Long Noncoding RNAs as Prognostic Signatures Associated with Oxidative Stress in Oral Cancer Based on Data from The Cancer Genome Atlas	7
Retracted: Automatic Detection and Segmentation of Ovarian Cancer Using a Multitask Model in Pelvic CT Images	7
Correction to “Oxidative and Inflammatory Mechanisms Induced by Intermittent Hypoxia Leading to Vascular Alterations in Rodents: A Systematic Review and Meta‐Analysis”	7
A Novel Prognostic Pyroptosis-Related Gene Signature Correlates to Oxidative Stress and Immune-Related Features in Gliomas	7
Retracted: A Novel Approach Combined with MIPO Technique for the Treatment of Type C Pilon Fractures	7
Erratum to “Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway”	7
RETRACTION: Probucol Protects Rats from Cardiac Dysfunction Induced by Oxidative Stress following Cardiopulmonary Resuscitation	7
MBNL1-AS1 Promotes Hypoxia-Induced Myocardial Infarction via the miR-132-3p/RAB14/CAMTA1 Axis	7
HSP90AB1 as the Druggable Target of Maggot Extract Reverses Cisplatin Resistance in Ovarian Cancer	7
E2f1 Overexpression Reduces Aging‐Associated DNA Damage in Cultured Cerebral Endothelial Cells and Improves Cognitive Performance in Aged Mice	6
Retracted: A Pharmacological Review of Tanshinones, Naturally Occurring Monomers from Salvia miltiorrhiza for the Treatment of Cardiovascular Diseases	6
Oxidative Stress in End-Stage Renal Disease: Pathophysiology and Potential Interventions	6
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens	6
Retracted: Mesenchymal Stem Cell-Derived Exosomes and Their Potential Agents in Hematological Diseases	6
Clinical Significance of Carnitine in the Treatment of Cancer: From Traffic to the Regulation	6
Corrigendum to “circAMOTL1L Suppresses Renal Cell Carcinoma Growth by Modulating the miR‐92a‐2‐5p/KLLN Pathway”	6
Retracted: S-Nitroso-L-Cysteine Ameliorated Pulmonary Hypertension in the MCT-Induced Rats through Anti-ROS and Anti-Inflammatory Pathways	6
Retracted: Tumor Necrosis Factor-Alpha Disrupts Cx43-Mediated Corneal Endothelial Gap Junction Intercellular Communication	6