OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	152
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	109
The Role of Membrane Lipids in the Formation and Function of Caveolae	103
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	99
Fisher's Geometric Model as a Tool to Study Speciation	77
Post-Translational Regulation of HMG CoA Reductase	70
Fibroblast Heterogeneity in Healthy and Wounded Skin	63
Angiogenesis in Wound Repair: Too Much of a Good Thing?	57
A History of Cancer Research: Retroviral Insertional Mutagenesis	56
A Mechanometabolism Toolbox for Studying Cell Migration	54
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	52
Telomere Dynamics in Human Health and Disease	51
Regulation of Human Telomerase: from Molecular Interactions to Population Genetics	51
Petabase-Scale Homology Search for Structure Prediction	49
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	47
Diversity of Fibroblasts and Their Roles in Wound Healing	47
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	46
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	44
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks	44
Maintaining Telomeres without Telomerase inDrosophila: Novel Mechanisms and Rapid Evolution to Save a Genus	43
Toward Understanding Wound Immunology for High-Fidelity Skin Regeneration	42
Mapping the Retina onto the Brain	41
Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	40
Blastocrithidia —A Genetic Alien from the Planet Earth	40
Interneuron Diversity: How Form Becomes Function	38

The Biology of Lipids	37
Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	37
Neotropics as a Cradle for Adaptive Radiations	36
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	33
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	32
Sticking to Membranes: Structure, Function, and Cellular Roles of the Annexin Family of Ca²⁺- and Membrane-Binding Proteins	31
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations	29
A History of Cancer Research: Oncogenic Transcription Factors	29
Variability in Neural Circuit Formation	29
Glial Cell Development and Function in the Zebrafish Central Nervous System	29
Combining Molecular, Macroevolutionary, and Macroecological Perspectives on the Generation of Diversity	29
Growth Factor and Cytokine Delivery Systems for Wound Healing	28
Regulators of Oligodendrocyte Differentiation	27
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	25
Machine Learning for Protein Science and Engineering	25
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	24
Calcium Signaling and Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Implications	24
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	24
Quantitative Analyses of Coupling in Hybrid Zones	24
Cancer Progression and the Calcium Signaling Toolkit: Expanding Dimensions and Perspectives	24
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	23
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective	23
Calcium Signaling in Migrating Neutrophils	22
Developmental Control of Cell Cycle and Signaling	22
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	20
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)	20
Caspases and Their Substrates	20
Transformation of Plantation Forestry Productivity for Climate Change Mitigation and Adaptation	20
Soft Matter Physics Meets Cell Biology: Transitions of Collective Cell Migration in 3D Environments	20
Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling	19
Glia at Transition Zones	19
Lipid Sorting and Organelle Identity	18
The Sensory Ecology of Speciation	18
Ca²⁺ Fluxes across Membrane Contact Sites	18
Glia Development and Function in the NematodeCaenorhabditis elegans	18
Remyelination in the Central Nervous System	17
Synthesis and Scope of the Role of Postmating Prezygotic Isolation in Speciation	17
Hidden Treasures of the Genetic Systems in Yeast Mitochondria	17
Development of Prefrontal Circuits and Cognitive Abilities	17
Structural Biology of Telomerase and Associated Factors	16