OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	109
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	106
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	87
Fisher's Geometric Model as a Tool to Study Speciation	85
The Role of Membrane Lipids in the Formation and Function of Caveolae	84
Nucleotide Metabolism	81
Fibroblast Heterogeneity in Healthy and Wounded Skin	79
Post-Translational Regulation of HMG CoA Reductase	78
Angiogenesis in Wound Repair: Too Much of a Good Thing?	76
A History of Cancer Research: Retroviral Insertional Mutagenesis	71
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	70
Telomere Dynamics in Human Health and Disease	67
The Impact of Space and Time on the Functional Output of the Genome	66
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	59
Petabase-Scale Homology Search for Structure Prediction	58
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	54
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	53
Regulation of Human Telomerase: from Molecular Interactions to Population Genetics	51
Modeling Normal and Abnormal Circuit Development with Recurrent Neural Networks	46
Diversity of Fibroblasts and Their Roles in Wound Healing	46
Mapping the Retina onto the Brain	45
Maintaining Telomeres without Telomerase inDrosophila: Novel Mechanisms and Rapid Evolution to Save a Genus	42
Toward Understanding Wound Immunology for High-Fidelity Skin Regeneration	42
Structural Diversity within the Endoplasmic Reticulum—From the Microscale to the Nanoscale	41
Interneuron Diversity: How Form Becomes Function	40

Mammalian Digit Tip Regeneration: Moving from Phenomenon to Molecular Mechanism	38
3D or Not 3D: Shaping the Genome during Development	38
The Biology of Lipids	37
Building and Maintaining the Skin	36
The Nuclear Lamina	34
A TAle of Two Pathways: Tail-Anchored Protein Insertion at the Endoplasmic Reticulum	34
Endoplasmic Reticulum Membrane Contact Sites, Lipid Transport, and Neurodegeneration	34
Neotropics as a Cradle for Adaptive Radiations	33
Lipid Transport from Endoplasmic Reticulum to Autophagic Membranes	32
Auxin in Root Development	31
Structure, Maintenance, and Regulation of Nuclear Pore Complexes: The Gatekeepers of the Eukaryotic Genome	31
Good Neighbors: The Niche that Fine Tunes Mammalian Intestinal Regeneration	31
A History of Cancer Research: Oncogenic Transcription Factors	28
Variability in Neural Circuit Formation	28
Machine Learning for Protein Science and Engineering	28
Combining Molecular, Macroevolutionary, and Macroecological Perspectives on the Generation of Diversity	27
Glial Cell Development and Function in the Zebrafish Central Nervous System	27
Why Do Some Lineages Radiate While Others Do Not? Perspectives for Future Research on Adaptive Radiations	27
Regulators of Oligodendrocyte Differentiation	26
Growth Factor and Cytokine Delivery Systems for Wound Healing	26
Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum	26
Inducing Vertebrate Limb Regeneration: A Review of Past Advances and Future Outlook	25
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	24
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	24
Essential Roles for RNA in Shaping Nuclear Organization	24
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	23
Sex Differences in Mast Cell–Associated Disorders: A Life Span Perspective	23
Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions	23
Polyploidy in Tissue Repair and Regeneration	22
The Diverse Manifestations of Regeneration and Why We Need to Study Them	21
Lipid Metabolism	21
Transformation of Plantation Forestry Productivity for Climate Change Mitigation and Adaptation	21
Quantitative Analyses of Coupling in Hybrid Zones	21
Nuclear Compartments: An Incomplete Primer to Nuclear Compartments, Bodies, and Genome Organization Relative to Nuclear Architecture	21
Caspases and Their Substrates	20
How Neuromembrane Lipids Modulate Membrane Proteins: Insights from G-Protein-Coupled Receptors (GPCRs) and Receptor Tyrosine Kinases (RTKs)	20
Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function	20
Developmental Control of Cell Cycle and Signaling	20
Glia Development and Function in the NematodeCaenorhabditis elegans	19
Cholesterol, Eukaryotic Lipid Domains, and an Evolutionary Perspective of Transmembrane Signaling	19
Glia at Transition Zones	19
The Sensory Ecology of Speciation	18
All for One and One for All: Regenerating Skeletal Muscle	18
Hidden Treasures of the Genetic Systems in Yeast Mitochondria	17
Remyelination in the Central Nervous System	17
Development of Prefrontal Circuits and Cognitive Abilities	17
Pancreatic β-Cell Development and Regeneration	17
Lipid Sorting and Organelle Identity	17