OOIR: Observatory of International Research

Papers

(The TQCC of Cold Spring Harbor Perspectives in Biology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Fisher's Geometric Model as a Tool to Study Speciation	193
Characterizing Large-Scale Human Circuit Development with In Vivo Neuroimaging	100
Cellular Contributions to Glymphatic and Lymphatic Waste Clearance in the Brain	97
Autophagy in Skeletal Muscle	87
The Diversity of Skeletal Muscle Fiber Types	79
Transcriptional Control of Cell Fate Determination in Antigen-Experienced CD8 T Cells	78
A Single-Cell Perspective on Memory T-Cell Differentiation	76
Evidence for Perinatal Steroid Influence on Human Sexual Orientation and Gendered Behavior	76
Essential Roles for RNA in Shaping Nuclear Organization	75
The Biogenesis of Multipass Membrane Proteins	71
Integrating Sex Chromosome and Endocrine Theories to Improve Teaching of Sexual Differentiation	68
Quantifying Sex Differences in Behavior in the Era of “Big” Data	66
Temporal and Epigenetic Control of Plasticity and Fate Decision during CD8⁺T-Cell Memory Differentiation	62
Post-Translational Regulation of HMG CoA Reductase	61
Structure and Function of the Nuclear Pore Complex	59
Teaching School Genetics in the 2020s: Why “Naive” Mendelian Genetics Has to Go	58
Membrane Epilipidome—Lipid Modifications, Their Dynamics, and Functional Significance	57
Hematopoietic Stem Cells and Regeneration	57
Understanding the Influence of Host Radiation on Symbiont Speciation through Parasites of Species Flocks	56
How Important Is Sexual Isolation to Speciation?	54
Reimagining Cortical Connectivity by Deconstructing Its Molecular Logic into Building Blocks	48
The Nodes of Ranvier: Mechanisms of Assembly and Maintenance	46
The Systems and Synthetic Biology of Auxin	45
Inducing Vertebrate Limb Regeneration: A Review of Past Advances and Future Outlook	44
Glia in Neurodegenerative Disease	41

Building Representation Learning Models for Antibody Comprehension	39
Glial Malignancies	39
Perisynaptic Schwann Cells: Guardians of Neuromuscular Junction Integrity and Function in Health and Disease	38
Role of Microglia in Central Nervous System Development and Plasticity	36
Telomeric Repeat-Containing RNA: Biogenesis, Regulation, and Functions	35
Legumes and Linguistics: Translating Mendel for the Twenty-First Century	35
Proteins of the Triadic Excitation–Contraction Coupling Complex in Skeletal Muscle	33
Angiogenesis in Wound Repair: Too Much of a Good Thing?	32
The Role of Membrane Lipids in the Formation and Function of Caveolae	32
Anthropogenic Change and the Process of Speciation	31
Cell Adhesion Molecule Signaling at the Synapse: Beyond the Scaffold	31
Fibroblast Heterogeneity in Healthy and Wounded Skin	31
Features, Fates, and Functions of Oligodendrocyte Precursor Cells	29
Fourteen Stations of Auxin	29
Sex Differences in Major Depressive Disorder (MDD) and Preclinical Animal Models for the Study of Depression	28
Phosphoinositides in New Spaces	28
Nucleotide Metabolism	27
Astrocyte Regulation of Synapse Formation, Maturation, and Elimination	26
The Death Receptor Pathway of Apoptosis	25
Mechanisms of Alternative Lengthening of Telomeres	25
Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing	24
Mechanisms of Intrinsic Postzygotic Isolation: From Traditional Genic and Chromosomal Views to Genomic and Epigenetic Perspectives	24
The Impact of Space and Time on the Functional Output of the Genome	24
In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function	24
Lipids in Extracellular Vesicles: What Can Be Learned about Membrane Structure and Function?	24
Cholesterol Transport to the Endoplasmic Reticulum	24
Mechanisms of Chromosome Folding and Nuclear Organization: Their Interplay and Open Questions	23
A History of Cancer Research: Retroviral Insertional Mutagenesis	23
Telomere Dynamics in Human Health and Disease	23
Niche Theory as an Underutilized Resource for the Study of Adaptive Radiations	22
The Role of Microhomology-Mediated End Joining (MMEJ) at Dysfunctional Telomeres	21
The Contribution of Innervation to Tissue Repair and Regeneration	21
Oxidative Stress and DNA Damage at Telomeres	21
Metabolic Control of Memory T-Cell Generation and Stemness	21
Uncovering How Auxin Optimizes Root Systems Architecture in Response to Environmental Stresses	20
Stairways to Advanced Therapies for Epidermolysis Bullosa	18
The Stochastic Genome and Its Role in Gene Expression	18
Evolutionary Aspects of the Unfolded Protein Response	18
Quantitative Analyses of Coupling in Hybrid Zones	17
Lipid Metabolism	17
Seeing the Membrane from Both Sides Now: Lipid Asymmetry and Its Strange Consequences	17
Caspase Activation and Inhibition	17
Genomic Approaches Are Improving Taxonomic Representation in Genetic Studies of Speciation	16
The Impact of Chromosomal Rearrangements in Speciation: From Micro- to Macroevolution	16
Predictability, an Orrery, and a Speciation Machine: Quest for a Standard Model of Speciation	16
Petabase-Scale Homology Search for Structure Prediction	16
Engineering Proteins Using Statistical Models of Coevolutionary Sequence Information	16