Science Signaling

Papers
(The H4-Index of Science Signaling is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Aging and age-related disorders, cell by cell139
Avoiding conflict with strigolactones129
Editorial expression of concern122
Estrogen-powered kidney protection103
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney86
Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons85
Cholinergic signals and antibodies79
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors77
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease69
Nuclear pore decoys fool viruses61
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization58
Pathogenic putrescine56
The protein RAB5IF promotes BDNF signaling by stimulating the SUMOylation of Gα i1/3 to reduce depressive-like behaviors in mice53
Human and mouse long noncoding RNAs reengineered for exogenous delivery reduce LPS-induced inflammation in human macrophages and mice50
A Caenorhabditis elegans spatiotemporal proximity atlas reveals the MAPK p38 as a generator of phenotypic plasticity in vivo50
Vagal activation inhibits insulin release through neuronal nitric oxide synthase in obese male mice49
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis46
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition45
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease45
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress44
APOE ε4 on immunity43
Turning a negative into a positive43
A sensitive biosensor of endogenous Gα i activity enables the accurate characterization of endogenous GPCR agonist responses43
Metabolic pressure from sensory neurons42
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation42
Ring around the mitochondria40
IL-33–ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways40
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke40
Lipid drops in on Alzheimer’s disease39
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth38
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses38
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells37
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment37
Gut bugs on drugs37
cAMPing up cancer immunotherapy36
The fragile state of opioid withdrawal36
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