Science Signaling

Papers
(The H4-Index of Science Signaling is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Pathogenic putrescine111
Avoiding conflict with strigolactones87
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress84
Aging and age-related disorders, cell by cell82
Editorial expression of concern78
Shining a light on rhodopsin signaling78
Transporting leptin to its targets68
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization65
Intrapore lipids hydrophobically gate pannexin-1 channels65
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney64
Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target64
Nuclear pore decoys fool viruses64
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors62
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition62
CISH attenuates homeostatic cytokine signaling to promote lung-specific macrophage programming and function55
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease54
SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways50
Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function49
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon–induced JAK-STAT signaling and activating STATs47
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis44
A lifeline for immunotherapy43
Insulin and T reg cells42
A sensitive biosensor of endogenous Gα i activity enables the accurate characterization of endogenous GPCR agonist responses42
Metabolic pressure from sensory neurons41
Lipid drops in on Alzheimer’s disease41
Ring around the mitochondria38
Turning a negative into a positive38
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis37
Targeting AML at the intersection of epigenetics and signaling37
The PdeK-PdeR two-component system promotes unipolar localization of FimX and pilus extension in Xanthomonas oryzae pv. oryzicola37
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth35
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment35
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses35
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke34
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells34
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