OOIR: Observatory of International Research

Papers

(The H4-Index of Science Signaling is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease	132
Brain-derived neurotrophic factor coordinates neuron-intrinsic programs to enhance axonal regeneration in human motor neurons	127
Cholinergic signals and antibodies	121
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors	97
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease	86
The protein RAB5IF promotes BDNF signaling by stimulating the SUMOylation of Gα _i1/3 to reduce depressive-like behaviors in mice	81
Aging and age-related disorders, cell by cell	79
Nuclear pore decoys fool viruses	75
Avoiding conflict with strigolactones	68
Editorial expression of concern	60
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition	56
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis	54
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization	53
Estrogen-powered kidney protection	52
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress	52
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney	49
Human and mouse long noncoding RNAs reengineered for exogenous delivery reduce LPS-induced inflammation in human macrophages and mice	47
Pathogenic putrescine	47
Turning a negative into a positive	45
APOE ε4 on immunity	44
A sensitive biosensor of endogenous Gα _i activity enables the accurate characterization of endogenous GPCR agonist responses	44
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis	43
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation	43
Metabolic pressure from sensory neurons	42
Lipid drops in on Alzheimer’s disease	41

Ring around the mitochondria	41
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses	40
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth	40
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells	39
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment	39
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke	39
IL-33–ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways	39
Telomeres to go	37
Gut bugs on drugs	37
The fragile state of opioid withdrawal	36
A metabolic regulator for parietal cells	36
cAMPing up cancer immunotherapy	36