OOIR: Observatory of International Research

Papers

(The H4-Index of Science Signaling is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Aging and age-related disorders, cell by cell	113
Nuclear pore decoys fool viruses	105
Shining a light on rhodopsin signaling	97
Pathogenic putrescine	94
Intrapore lipids hydrophobically gate pannexin-1 channels	81
Avoiding conflict with strigolactones	80
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress	79
Editorial expression of concern	70
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease	70
Estrogen-powered kidney protection	68
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors	65
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease	63
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization	63
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney	62
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis	51
Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target	48
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition	46
APOE ε4 on immunity	45
Turning a negative into a positive	45
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation	44
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment	44
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses	44
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth	42
A sensitive biosensor of endogenous Gα _i activity enables the accurate characterization of endogenous GPCR agonist responses	42
Targeting AML at the intersection of epigenetics and signaling	40

Lipid drops in on Alzheimer’s disease	40
Metabolic pressure from sensory neurons	40
Ring around the mitochondria	39
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke	38
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells	38
SARS-CoV-2 spike protein–induced cell fusion activates the cGAS-STING pathway and the interferon response	38
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis	38
IL-33–ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways	37
Telomeres to go	35
Gut bugs on drugs	35
The fragile state of opioid withdrawal	35
Modulation by macrocyclic peptides	35
cAMPing up cancer immunotherapy	35
A metabolic regulator for parietal cells	35