OOIR: Observatory of International Research

Papers

(The H4-Index of Science Signaling is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization	107
Signaling dynamics distinguish high- and low-priority neutrophil chemoattractant receptors	95
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney	93
TRPM7 kinase activity induces amyloid-β degradation to reverse synaptic and cognitive deficits in mouse models of Alzheimer’s disease	91
Nuclear pore decoys fool viruses	79
Aging and age-related disorders, cell by cell	79
Shining a light on rhodopsin signaling	78
Pathogenic putrescine	75
Intrapore lipids hydrophobically gate pannexin-1 channels	74
Avoiding conflict with strigolactones	66
ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress	65
Editorial expression of concern	64
A PKCη missense mutation enhances Golgi-localized signaling and is associated with recessively inherited familial Alzheimer’s disease	61
Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition	61
Estrogen-powered kidney protection	60
Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target	59
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon–induced JAK-STAT signaling and activating STATs	58
TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis	50
IL-33–ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways	47
Turning a negative into a positive	46
APOE ε4 on immunity	45
Degradation of HDAC10 by autophagy promotes IRF3-mediated antiviral innate immune responses	44
Ring around the mitochondria	43
A sensitive biosensor of endogenous Gα _i activity enables the accurate characterization of endogenous GPCR agonist responses	43
Lipid drops in on Alzheimer’s disease	42

Targeting AML at the intersection of epigenetics and signaling	41
Metabolic pressure from sensory neurons	41
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation	40
Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth	39
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis	39
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke	39
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells	38
SARS-CoV-2 spike protein–induced cell fusion activates the cGAS-STING pathway and the interferon response	38
Telomeres to go	37
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment	37
Gut bugs on drugs	36