OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	253
Correction for: LncRNA LOC146880 promotes esophageal squamous cell carcinoma progression via miR-328-5p/FSCN1/MAPK axis	160
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	103
	88
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	86
DNA methylation entropy is a biomarker for aging	85
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	82
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	77
Vascular function in the aging human brain during muscle exertion	73
Identification and external validation of the hub genes associated with cardiorenal syndrome through time-series and network analyses	72
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	66
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	62
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	62
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	58
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages	58
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	55
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	52
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	45
The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study	44
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	43
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy	43
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy	42
In vivo tau staging in Alzheimer’s disease	41
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC	41
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	41

Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	41
BMAL1 modulates senescence programming via AP-1	40
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	40
The impact of ALDH7A1 variants in oral cancer development and prognosis	39
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	39
miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway	37
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	37
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	36
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer	36
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	36
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	36