OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
	264
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	171
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	116
Vascular function in the aging human brain during muscle exertion	98
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	91
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	86
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	83
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	78
In vivo tau staging in Alzheimer’s disease	76
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	67
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	66
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	59
The impact of ALDH7A1 variants in oral cancer development and prognosis	55
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	55
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	50
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	47
miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway	46
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	45
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	43
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	42
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	42
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies	42
Mapping the core senescence phenotype of primary human colon fibroblasts	42
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	42
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	40

THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	40
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	40
Organotypic cultures as aging associated disease models	39
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	39
Identification and external validation of the hub genes associated with cardiorenal syndrome through time-series and network analyses	38
BMAL1 modulates senescence programming via AP-1	37
F12 as a reliable diagnostic and prognostic biomarker associated with immune infiltration in papillary thyroid cancer	36
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	36
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer	36
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	36
Epigenetic aging signatures and age prediction in human skeletal muscle	36
Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway	36