OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
	285
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	155
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	125
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	91
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	65
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	54
ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function	54
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	51
In vivo tau staging in Alzheimer’s disease	47
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	46
Epigenetic aging signatures and age prediction in human skeletal muscle	45
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	45
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages	45
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	44
Organotypic cultures as aging associated disease models	44
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	43
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	43
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	42
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma	42
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	41
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies	40
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	40
DNA methylation entropy is a biomarker for aging	40
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	40
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	39

BMAL1 modulates senescence programming via AP-1	39
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy	38
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	38
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	38
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	38
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	38
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy	36
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	35
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer	35
The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study	34