OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
	264
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	171
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	116
Vascular function in the aging human brain during muscle exertion	98
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	91
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	86
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	83
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	78
In vivo tau staging in Alzheimer’s disease	76
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	67
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	66
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	59
The impact of ALDH7A1 variants in oral cancer development and prognosis	55
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	55
Association between dipeptidyl peptidase-4 inhibitor use and risk of Parkinson’s disease among patients with diabetes mellitus: a retrospective cohort study	50
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	47
miRNA-29 aggravates myocardial infarction via inhibiting the PI3K/mTOR/HIF1α/VEGF pathway	46
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	45
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	43
Mapping the core senescence phenotype of primary human colon fibroblasts	42
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	42
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	42
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	42
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies	42
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma	40

Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	40
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	40
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	39
Organotypic cultures as aging associated disease models	39
Identification and external validation of the hub genes associated with cardiorenal syndrome through time-series and network analyses	38
BMAL1 modulates senescence programming via AP-1	37
F12 as a reliable diagnostic and prognostic biomarker associated with immune infiltration in papillary thyroid cancer	36
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	36
Unraveling the unfolded protein response signature: implications for tumor immune microenvironment heterogeneity and clinical prognosis in stomach cancer	36
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	36
Epigenetic aging signatures and age prediction in human skeletal muscle	36
Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway	36