OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Correction for: Prediction of cognitive performance in old age from spatial probability maps of white matter lesions	219
Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer	212
High red blood cell distribution width levels could increase the risk of hemorrhagic transformation after intravenous thrombolysis in acute ischemic stroke patients	123
Prognostic and clinicopathological significance of prognostic nutritional index (PNI) in patients with oral cancer: a meta-analysis	79
Internal modulation of proteolysis in vascular extracellular matrix remodeling: role of ADAM metallopeptidase with thrombospondin type 1 motif 5 in the development of intracranial aneurysm rupture	77
Single-cell and bulk RNA sequencing data jointly reveals VDAC2’s impacts on prognosis and immune landscape of NSCLC	74
GAS5, a long noncoding RNA, contributes to annulus fibroblast osteogenic differentiation and apoptosis in intervertebral disk degeneration via the miR-221-3p/SOX11 axis	70
Mapping the core senescence phenotype of primary human colon fibroblasts	67
The high expression of TOP2A and MELK induces the occurrence of psoriasis	64
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	63
A retrospective study on the effect of Chinese patent medicine combined with conventional treatment on the survival outcomes of 313 patients with stage II–III NSCLC	62
Potential value of expression of receptor accessory protein 4 for evaluating the prognosis of lower-grade glioma patients	61
HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2	58
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	58
Using genetics and proteomics data to identify proteins causally related to COVID-19, healthspan and lifespan: a Mendelian randomization study	58
MKRN2 inhibits the proliferation of gastric cancer by downregulating PKM2	57
Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation	56
Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses	56
	55
Prognostic and immunological value of ATP6AP1 in breast cancer: implications for SARS-CoV-2	53
Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1	53
Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response	53
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	52
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	52
DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis	51

Retraction of: The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma	51
Correction for: Efficacy and safety of recombinant human follicle-stimulating hormone in patients undergoing in vitro fertilization-embryo transfer	51
Retraction for: Cationic solid lipid nanoparticles loaded by integrin β1 plasmid DNA attenuates IL-1β-induced apoptosis of chondrocyte	51
Effects of Qidantang Granule on early stage of diabetic kidney disease in rats	50
Retraction: MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling	50
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	49
Correction for: 1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5’-adenosine monophosphate-activated protein kinase activity via the peroxisome proli	46
MCF2L-AS1 promotes the biological behaviors of hepatocellular carcinoma cells by regulating the miR-33a-5p/FGF2 axis	46
A stemness-based signature with inspiring indications in discriminating the prognosis, immune response, and somatic mutation of endometrial cancer patients revealed by machine learning	44
Correction for: Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and	44
	44
Recalibrate concepts of epigenetic aging clocks in human health	44
A bi-directional Mendelian randomization study of the sarcopenia-related traits and osteoporosis	43
Effectiveness of vaginal probiotics Lactobacillus crispatus chen-01 in women with high-risk HPV infection: a prospective controlled pilot study	43
Stopping the aged brain from eating itself	42
LncRNA PlncRNA-1 accelerates the progression of prostate cancer by regulating PTEN/Akt axis	42
The theory of orchid and dandelion offers a new subtyping framework for cognitive aging	42
Machine learning algorithm integrates bulk and single-cell transcriptome sequencing to reveal immune-related personalized therapy prediction features for pancreatic cancer	42