OOIR: Observatory of International Research

Papers

(The H4-Index of Aging-US is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Advanced age is not the decisive factor in chemotherapy of small cell lung cancer: a population-based study	223
Serum adenosine deaminase activity and acute cerebral infarction: a retrospective case-control study based on 7913 participants	134
DNA methylation entropy is a biomarker for aging	80
Clinical characterization and therapeutic targets of vitamin A in patients with hepatocholangiocarcinoma and coronavirus disease	79
Vascular function in the aging human brain during muscle exertion	73
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy	72
Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder	71
PUS1 is a novel biomarker for evaluating malignancy of human renal cell carcinoma	70
CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction	69
Identification and validation of oxeiptosis-associated lncRNAs and prognosis-related signature genes to predict the immune status in uterine corpus endometrial carcinoma	69
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis	68
Correction for: Circular RNA Plek promotes fibrogenic activation by regulating the miR-135b-5p/TGF-βR1 axis after spinal cord injury	67
Correction for: LncRNA LOC146880 promotes esophageal squamous cell carcinoma progression via miR-328-5p/FSCN1/MAPK axis	64
Brief, weekly magnetic muscle therapy improves mobility and lean body mass in older adults: a Southeast Asia community case study	61
Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma	60
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats	60
	57
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies	57
Multilevel data integration and molecular docking approach to systematically elucidate the underlying pharmacological mechanisms of Er-Zhi-Wan against hepatocellular carcinoma	56
Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway	56
S100A9, as a potential predictor of prognosis and immunotherapy response for GBM, promotes the malignant progression of GBM cells and migration of M2 macrophages	54
BMAL1 modulates senescence programming via AP-1	52
Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study	52
	52
In vivo tau staging in Alzheimer’s disease	51

Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma	51
Identification and external validation of the hub genes associated with cardiorenal syndrome through time-series and network analyses	49
THY1 is a prognostic-related biomarker via mediating immune infiltration in lung squamous cell carcinoma (LUSC)	47
Two lncRNA signatures with cuproptosis as a novel prognostic model and clinicopathological value for endometrioid endometrial adenocarcinoma	46
Anemoside B4 sensitizes human colorectal cancer to fluorouracil-based chemotherapy through src-mediated cell apoptosis	46
Pan-cancer analysis of disulfidptosis with potential implications in prognosis, immune microenvironment, and drug resistance in human cancer	45
Correction: Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial	45
An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis	44
Bisphosphonates and breast cancer survival: a meta-analysis and trial sequential analysis of 81508 participants from 23 prospective epidemiological studies	44
Clinicopathological and prognostic value of long noncoding RNA SNHG7 in cancers: a meta-analysis and bioinformatics	44
Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results	42
Organotypic cultures as aging associated disease models	42
Identification and validation of immunogenic cell death-related score in uveal melanoma to improve prediction of prognosis and response to immunotherapy	42
LINC02362 attenuates hepatocellular carcinoma progression through the miR-516b-5p/SOSC2 axis	41
LncRNA DANCR suppresses acute myocardial infarction in mice via mediating p-RXRA/TRAF2/NIK/IKK/NF-κB signaling pathway	41
Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility tri	40
Prognostic and immunological value of ATP6AP1 in breast cancer: implications for SARS-CoV-2	40