Science Translational Medicine

Papers
(The median citation count of Science Translational Medicine is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
IgA dominates the early neutralizing antibody response to SARS-CoV-2778
A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples474
Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19474
Enhanced SARS-CoV-2 neutralization by dimeric IgA365
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates327
COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters319
COVID-19 diagnostics in context287
Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients285
Importance of the pig as a human biomedical model246
A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus242
Lung transplantation for patients with severe COVID-19237
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma224
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations218
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis205
Advanced bandages for diabetic wound healing196
Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome194
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection192
Prospects for a safe COVID-19 vaccine189
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2187
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys182
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice180
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance177
An Alphavirus -derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates172
Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits169
Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors168
Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice168
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models161
Sampling interstitial fluid from human skin using a microneedle patch158
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages155
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19154
Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection152
The past, present, and future of antibiotics150
Bioadhesive hydrogels demonstrating pH-independent and ultrafast gelation promote gastric ulcer healing in pigs150
Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy148
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia147
Teplizumab improves and stabilizes beta cell function in antibody-positive high-risk individuals146
Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide140
The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans140
A first-in-human phase 0 clinical study of RNA interference–based spherical nucleic acids in patients with recurrent glioblastoma140
Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys139
Effective combination immunotherapy using oncolytic viruses to deliver CAR targets to solid tumors139
iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapy136
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19136
Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice135
siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice132
Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity128
Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome127
T cell and antibody kinetics delineate SARS-CoV-2 peptides mediating long-term immune responses in COVID-19 convalescent individuals127
cGAS-STING–mediated DNA sensing maintains CD8 + T cell stemness and promotes antitumor T cell therapy126
Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy124
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery123
Reproducibility in machine learning for health research: Still a ways to go121
Acute inflammatory response via neutrophil activation protects against the development of chronic pain121
ctDNA monitoring using patient-specific sequencing and integration of variant reads120
Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy120
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice119
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia118
Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine116
SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19115
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection114
Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines114
Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma114
In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness113
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases113
In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer’s disease pathology and cognitive decline112
Smartwatch inertial sensors continuously monitor real-world motor fluctuations in Parkinson’s disease111
PRMT5 control of cGAS/STING and NLRC5 pathways defines melanoma response to antitumor immunity111
C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy111
Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils110
Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease110
Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models110
The cortical origin and initial spread of medial temporal tauopathy in Alzheimer’s disease assessed with positron emission tomography109
SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models108
Nicotinamide for the treatment of heart failure with preserved ejection fraction107
Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms107
A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease103
Reprogramming lipid metabolism prevents effector T cell senescence and enhances tumor immunotherapy103
Chi3l1 /YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer’s disease pathogenesis102
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses102
Predicting the mutational drivers of future SARS-CoV-2 variants of concern101
Biology of antimicrobial resistance and approaches to combat it101
Toward robust mammography-based models for breast cancer risk100
Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation100
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates100
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms100
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions99
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States99
Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients98
Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice97
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination97
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components95
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension94
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy94
Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade93
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia92
Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits91
Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses91
Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma91
Wireless sensors for continuous, multimodal measurements at the skin interface with lower limb prostheses90
Macrophage-tumor chimeric exosomes accumulate in lymph node and tumor to activate the immune response and the tumor microenvironment89
A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles89
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy88
Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis88
Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells88
Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy87
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases85
Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates85
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair85
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice84
Targeting cartilage EGFR pathway for osteoarthritis treatment84
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models84
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice84
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset83
Predicting functional effects of missense variants in voltage-gated sodium and calcium channels83
ARID1A mutation plus CXCL13 expression act as combinatorial biomarkers to predict responses to immune checkpoint therapy in mUCC83
Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses83
Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines83
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease82
Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor82
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence81
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans80
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury80
Granzyme K + CD8 T cells form a core population in inflamed human tissue80
Using deep learning for dermatologist-level detection of suspicious pigmented skin lesions from wide-field images79
Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma79
Trispecific CD19-CD20-CD22–targeting duoCAR-T cells eliminate antigen-heterogeneous B cell tumors in preclinical models78
Molecular and functional extracellular vesicle analysis using nanopatterned microchips monitors tumor progression and metastasis78
APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function77
BCG vaccination–induced emergency granulopoiesis provides rapid protection from neonatal sepsis76
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern76
Using influenza surveillance networks to estimate state-specific prevalence of SARS-CoV-2 in the United States76
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease75
An oral antisense oligonucleotide for PCSK9 inhibition75
An off-the-shelf bioadhesive patch for sutureless repair of gastrointestinal defects74
In vivo prime editing of a metabolic liver disease in mice74
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria74
MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation74
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire73
mRNA vaccination induces tick resistance and prevents transmission of the Lyme disease agent73
Gene editing to induce FOXP3 expression in human CD4 + T cells leads to a stable regulatory phenotype and function73
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity73
Oncolytic virus–mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice73
Cellular senescence impairs the reversibility of pulmonary arterial hypertension73
Single-cell transcriptional landscapes reveal HIV-1–driven aberrant host gene transcription as a potential therapeutic target72
COVID-19 mRNA vaccines drive differential antibody Fc-functional profiles in pregnant, lactating, and nonpregnant women72
Intracavity generation of glioma stem cell–specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy72
Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans71
A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates71
Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England71
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice70
Stereotypic neutralizing V H antibodies against SARS-CoV-2 spike protein receptor binding domain in patients with COVID-19 and healthy individuals70
Immunocytokines are a promising immunotherapeutic approach against glioblastoma70
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma69
Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS69
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes69
Soft, skin-interfaced sweat stickers for cystic fibrosis diagnosis and management69
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models69
Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity69
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort69
Cardiac ryanodine receptor calcium release deficiency syndrome69
Brain circuits for pain and its treatment68
Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models68
Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration68
Academic careers and the COVID-19 pandemic: Reversing the tide68
Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction67
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-1966
Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair66
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip66
SARS-CoV-2 BA.1 variant is neutralized by vaccine booster–elicited serum but evades most convalescent serum and therapeutic antibodies66
Lung cancer scRNA-seq and lipidomics reveal aberrant lipid metabolism for early-stage diagnosis65
Staphylococcus Agr virulence is critical for epidermal colonization and associates with atopic dermatitis development65
SARS-CoV-2 3CL pro mutations selected in a VSV-based system confer resistance to nirmatrelvir, ensitrelvir, and GC37664
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia64
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers64
Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study64
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice64
Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics64
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations63
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies63
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment63
Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite63
Mutant huntingtin and neurofilament light have distinct longitudinal dynamics in Huntington’s disease63
Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model62
Citrullinated vimentin mediates development and progression of lung fibrosis62
Blocking immunosuppressive neutrophils deters pY696-EZH2–driven brain metastases62
Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition62
Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease62
A probiotic yeast-based immunotherapy against Clostridioides difficile infection62
AMELIE speeds Mendelian diagnosis by matching patient phenotype and genotype to primary literature62
Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche62
Platelets release mitochondrial antigens in systemic lupus erythematosus61
Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia61
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro61
Persistent post–COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium61
Druggable cancer phosphatases61
Chimeric STAR receptors using TCR machinery mediate robust responses against solid tumors61
Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy60
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis60
Clonal IgA and IgG autoantibodies from individuals at risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum59
Long-lasting analgesia via targeted in situ repression of Na V 1.7 in mice59
A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma58
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia58
Long-term skin-resident memory T cells proliferate in situ and are involved in human graft-versus-host disease58
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice58
Development and deployment of COVID-19 vaccines for those most vulnerable58
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis58
Elastin-like recombinamers-based hydrogel modulates post-ischemic remodeling in a non-transmural myocardial infarction in sheep58
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling57
A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults57
Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA57
Cardiosphere-derived exosomal microRNAs for myocardial repair in pediatric dilated cardiomyopathy57
Transplanted microvessels improve pluripotent stem cell–derived cardiomyocyte engraftment and cardiac function after infarction in rats57
A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression57
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models56
A recombinant spike protein subunit vaccine confers protective immunity against SARS-CoV-2 infection and transmission in hamsters56
Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade56
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation56
De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection56
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents55
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis55
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy55
LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade55
Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption55
Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses55
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models54
Risk assessment with gut microbiome and metabolite markers in NAFLD development54
SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages54
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice54
Persistently activated, proliferative memory autoreactive B cells promote inflammation in rheumatoid arthritis54
Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice54
AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation54
CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression53
Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests53
Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models53
Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy53
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies53
Plasma neurofilament light predicts mortality in patients with stroke53
Mechanism and reversal of drug-induced nephrotoxicity on a chip52
LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies52
Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus52
Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer52
Infection or a third dose of mRNA vaccine elicits neutralizing antibody responses against SARS-CoV-2 in kidney transplant recipients51
scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in T reg function51
Broad neutralization of H1 and H3 viruses by adjuvanted influenza HA stem vaccines in nonhuman primates51
Interleukin-2 signals converge in a lymphoid–dendritic cell pathway that promotes anticancer immunity51
Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel51
Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy51
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair51
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia51
Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti–PD-1 for patients with anti–PD-1–refractory tumors51
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