Science Translational Medicine

Article	Citations
Erratum for the Research Article: “Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis” by M. Scherlinger, V. Guillotin, I. Douchet, P. Vacher, A. B	449
Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy	379
A risk model for digital breast tomosynthesis to predict breast cancer and guide clinical care	366
Stronger regulation of AI in biomedicine	296
Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer	287
Increased brain microvascular hemoglobin concentrations in children with cerebral malaria	225
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancer	217
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer	210
Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer	204
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms	198
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment	195
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting	189
Evolution of inflammation and immunity in a dengue virus 1 human infection model	186
Point-of-care diagnostic tests for tuberculosis disease	185
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant	185
Antigenic distance between primary and secondary dengue infections correlates with disease risk	180
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens	180
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice	179
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies	178
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair	176
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine	171
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8 + T cells	169
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B.1.1.529) in England	168
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery	167
In vivo gene immunotherapy for cancer	163

Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome	162
A tale of two cells: Regulatory T cell–microglia cross-talk in the ischemic brain	161
A first-in-human study of the fibroblast activation protein–targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors	157
Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics	156
Advancing beyond the twists and turns of T cell exhaustion in cancer	153
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging	141
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection	140
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia	137
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes	136
A self-amplifying loop of YAP and SHH drives formation and expansion of heterotopic ossification	134
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer	134
Engineering CAR-T therapies for autoimmune disease and beyond	134
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment	131
Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation	128
Erratum for the Research Article: “The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis” by S. S. Pullamsetti, R. Savai, R. Dumitrascu, B. K. Dahal, J. Wilhelm, M. Koni	127
Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection	121
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry	120
A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis	119
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease	119
Rapid closure and hemostasis of ruptured soft tissues using a modified human tropoelastin-based sealant in preclinical models	118
MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson’s disease	115
Improved control of a prosthetic limb by surgically creating electro-neuromuscular constructs with implanted electrodes	115
Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans	114
Development and preclinical validation of 2-deoxy 2-[ 18 F]fluorocellobiose as an Aspergillus -specific PET tracer	113
Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas	112
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager	112
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis	111
NAD + precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction	111
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting	110
Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors	110
Next-generation CAR T cell therapies for glioblastoma	107
Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa	106
Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons	106
The pancreatic clock is a key determinant of pancreatic fibrosis progression and exocrine dysfunction	106
The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons	106
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models	103
4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2 -encephalopathy	103
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease	102
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron	102
TREM1 activation of myeloid cells promotes antitumor immunity	102
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation	100
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia	100
Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer	100
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice	99
Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models	99
Translating insights into therapies for Long Covid	99
Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe	99
Integrating the gut microbiome and pharmacology	99
Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)	98
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy	97

Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation	97
Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models	96
An ACE inhibitor reduces bactericidal activity of human neutrophils in vitro and impairs mouse neutrophil activity in vivo	96
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria	95
Short-course combination treatment for experimental chronic Chagas disease	95
A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis	94
A nose for tau	94
Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model	93
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice	93
Diet shapes the metabolite profile in the intact human ileum, which affects PYY release	92
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria	92
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis	91
Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial	91
Obesity and lifespan, a complex tango	91
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders	91
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer	90
Wastewater surveillance facilitates climate change–resilient pathogen monitoring	90
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration	90
Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors	90
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months	90
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire	89
Multicellular modeling of ciliopathy by combining iPS cells and microfluidic airway-on-a-chip technology	89
Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes	88
The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants	88
T cell receptor precision editing of regulatory T cells for celiac disease	87
Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease	87
CD23 + IgG1 + memory B cells are poised to switch to pathogenic IgE production in food allergy	87
Harnessing regulatory T cells to establish immune tolerance	86
Assessment of cholesterol homeostasis in the living human brain	86
Innate PD-L1 limits T cell–mediated adipose tissue inflammation and ameliorates diet-induced obesity	85
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort	84
Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire	83
Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis	82
Erratum for the Research Article “A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer” by A. M. Miller et al<	81
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice	81
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment	81
Treatment with ROS detoxifying gold quantum clusters alleviates the functional decline in a mouse model of Friedreich ataxia	80
Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers	80
Collagen V regulates renal function after kidney injury and can be pharmacologically targeted to enhance kidney repair in mice	80
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis	80
Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice	79
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins	79
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases	79
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice	78
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection	78
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models	78
Sex, lean body mass, and cardiac performance	78
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria	78
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia	76
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection	76
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease	76
Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neurons	75
Translating the evolving molecular landscape of tumors to biomarkers of response for cancer immunotherapy	75
T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models	75
An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans	75
IgE in allergy: It takes two	75
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19	74
Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer	74
Simultaneous analysis of mutations and methylations in circulating cell-free DNA for hepatocellular carcinoma detection	73
Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing	73
Targeting cytokines in inflammatory bowel disease	72
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair	72
MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis	72
Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction	71
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell–mediated antitumor immune response	70
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation	70
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis	70
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis	70
Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice	69
Immune responses to gut bacteria associated with time to diagnosis and clinical response to T cell–directed therapy for type 1 diabetes prevention	69
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor	69
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice	69
Erratum for the Research Article: “Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses” by E. A. Bordt, L. L. Shook, C. Atyeo, K. M. Pullen, R. M. De Guzman, M.-C. Mein	68
Green light analgesia in mice is mediated by visual activation of enkephalinergic neurons in the ventrolateral geniculate nucleus	68
Erratum for the Research Article “Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4” by Y. Ren et al .	68
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases	68
Erratum for the Research Article “Platelet-derived growth factor C signaling is a potential therapeutic target for radiation proctopathy” by W. Lu et al .	68
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging	67
Spatial genomics: Mapping the landscape of fibrosis	67
Identifying and targeting the Achilles heel of a recalcitrant cancer	67

A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma	67
Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models	66
Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration	66
Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”	66
Seeking satiety: From signals to solutions	66
Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models	65
New government drug repurposing programs: Opportunities and uncertainties	64
Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant–associated infections	64
Blocking common γ chain cytokine signaling ameliorates T cell–mediated pathogenesis in disease models	64
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease	64
Human OX40L–CAR-T regs target activated antigen-presenting cells and control T cell alloreactivity	64
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice	63
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer	63
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer	63
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19	63
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection	63
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology	63
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease	63
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis	63
Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease	63
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers	62
An AAV gene therapy computes over multiple cellular inputs to enable precise targeting of multifocal hepatocellular carcinoma in mice	62
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due toTTNmutations	62
Neuromodulation using ultra low frequency current waveform reversibly blocks axonal conduction and chronic pain	62
Delivery of therapeutic carbon monoxide by gas-entrapping materials	62
NF-κB perturbation reveals unique immunomodulatory functions in Prx1 + fibroblasts that promote development of atopic dermatitis	62
Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device	61
Repeated Omicron exposures redirect SARS-CoV-2–specific memory B cell evolution toward the latest variants	61
Allergy: Mechanistic insights into new methods of prevention and therapy	60
Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice	60
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 6	60
Interleukin-2–based therapies in cancer	60
In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis	60
Neuroinflammation: An astrocyte perspective	60
Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit	60
Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases	59
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos	59
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models	59
Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics	59
Resident microbes shape the vaginal epithelial glycan landscape	58
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease	58
Erratum for the Research Article “Boosting systemic absorption of peptides with a bioinspired buccal-stretching patch,” by Z. Luo et al .	58
Predicting the next round of drugs for Medicare price negotiation	57
Functional human IgA targets a conserved site on malaria sporozoites	57
Response to comment on “Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics”	56
Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem–specific human B cells	56
GABABreceptor modulation of visual sensory processing in adults with and without autism spectrum disorder	56
Triple knockdown of CD11a , CD49d , and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity	56
Protein kinase Cι mediates immunosuppression in lung adenocarcinoma	55
A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury	55
Response to Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”	55
Provocateurs of autoimmunity within the gut microbiota	55
Where do the pathogens that cause surgical site infections come from?	55
Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients	54
Donor-derived regulatory dendritic cell infusion modulates effector CD8+T cell and NK cell responses after liver transplantation	54
An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus	54
Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis	54
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy	53
A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques	53
Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets	53
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model	53
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human	53
Learning CNS immunopathology from therapeutic interventions	53
T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-19	53
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria	53
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19	52
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes	52
Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected	52
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses	52
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase	52
Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis	51
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy	51
The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination	51
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer	51
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid	51
Alpelisib administration reduced lymphatic malformations in a mouse model and in patients	51
Erratum for the Research Article “Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia” by R. Sartori et al .	51
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease	51
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML	50
Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation	50
An identity crisis for lung cancer cells	50
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity	50
Increased β 2 -adrenergic signaling promotes fracture healing through callus neovascularization in mice	50
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers	50
Vaccines for a sustainable planet	49
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency	49
Keratinocytes: From passive targets to active mediators of systemic autoimmunity	49
Guanosine diphosphate–mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer	49
A new chapter in lipid signaling and kidney fibrosis	49
Response to Comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”	49
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis	48
Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy	48
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease	48
Population-level implications of the Israeli booster campaign to curtail COVID-19 resurgence	48
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models	48