Science Translational Medicine

Article	Citations
Decreased mitochondrial creatine kinase 2 impairs skeletal muscle mitochondrial function independently of insulin in type 2 diabetes	413
Increased β 2 -adrenergic signaling promotes fracture healing through callus neovascularization in mice	366
A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke	364
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system	327
Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics	320
Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation	276
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8 + T cells	272
Navigating regulatory pathways for translation of biologic cartilage repair products	223
Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation	198
Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection	198
Evidence for the contribution of the gut microbiome to obesity and its reversal	194
Stronger regulation of AI in biomedicine	190
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer	190
Transient anti-interferon autoantibodies in the airways are associated with recovery from COVID-19	183
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancer	182
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection	177
Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model	176
Pandemic preparedness strategies must go beyond vaccines	173
An identity crisis for lung cancer cells	172
Targeting electrochemical communication between neurons and cancer	171
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes	165
Next-generation RSV vaccines avoid flipping out	160
The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells	158
An ASO therapy for Angelman syndrome that targets an evolutionarily conserved region at the start of the UBE3A-AS transcript	157
Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia	156

What’s next for cancer vaccines	156
Proteomic analysis of Alzheimer’s disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment	155
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models	153
Giredestrant reverses progesterone hypersensitivity driven by estrogen receptor mutations in breast cancer	150
FcγRIIB expressed on CD8+T cells limits responsiveness to PD-1 checkpoint inhibition in cancer	147
The tumor microenvironment state associates with response to HPV therapeutic vaccination in patients with respiratory papillomatosis	146
Response to Comment on “Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice”	143
Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity	143
Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose	142
A risk model for digital breast tomosynthesis to predict breast cancer and guide clinical care	132
Erratum for the Research Article: “Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis” by M. Scherlinger, V. Guillotin, I. Douchet, P. Vacher, A. B	131
In-line miniature 3D-printed pressure-cycled ventilator maintains respiratory homeostasis in swine with induced acute pulmonary injury	131
Characterization of clonal dynamics using duplex sequencing in donor-recipient pairs decades after hematopoietic cell transplantation	131
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment	131
Advancing beyond the twists and turns of T cell exhaustion in cancer	129
What keeps me up at night	127
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer	123
Prior infection with SARS-CoV-2 WA1/2020 partially protects rhesus macaques against reinfection with B.1.1.7 and B.1.351 variants	123
A tale of two cells: Regulatory T cell–microglia cross-talk in the ischemic brain	121
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis	120
Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy	118
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor models	116
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms	115
PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections	114
A metabolic role for CD47 in pancreatic β cell insulin secretion and islet transplant outcomes	113
Passive monitoring by smart toilets for precision health	113
Restoring arm function with a soft robotic wearable for individuals with amyotrophic lateral sclerosis	110
Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds	109
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers	109
Immunity elicited by natural infection or Ad26.COV2.S vaccination protects hamsters against SARS-CoV-2 variants of concern	108
An anti–TNF–glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases	107
Calreticulin mutant myeloproliferative neoplasms induce MHC-I skewing, which can be overcome by an optimized peptide cancer vaccine	106
Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma	105
Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains	104
Point-of-care diagnostic tests for tuberculosis disease	104
Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea in diabetes	101
Increased brain microvascular hemoglobin concentrations in children with cerebral malaria	101
Drug discovery in Africa tackles zoonotic and related infections	100
Erratum for the Research Article “Characterization of initial key steps of IL-17 receptor B oncogenic signaling for targeted therapy of pancreatic cancer” by H.-H. Wu et al	100
A new chapter in lipid signaling and kidney fibrosis	100
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant	100
Closing the loop on adrenal health, dysfunction, and disease	99
The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination	99
High-frequency epidural electrical stimulation reduces spasticity and facilitates walking recovery in patients with spinal cord injury	98
Sexual dimorphism in functional pain syndromes	98
Enhancing GAT-3 in thalamic astrocytes promotes resilience to brain injury in rodents	98
Keratinocytes: From passive targets to active mediators of systemic autoimmunity	98
Gene therapy targeting protein trafficking regulator MOG1 in mouse models of Brugada syndrome, arrhythmias, and mild cardiomyopathy	96
Clinical relevance of engineered cartilage maturation in a randomized multicenter trial for articular cartilage repair	96
A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response	95

Reduced cerebellar rhythm by climbing fiber denervation is linked to motor rhythm deficits in mice and ataxia severity in patients	95
Vaccines for a sustainable planet	94
Ectopic activation of the miR-200c–EpCAM axis enhances antitumor T cell responses in models of adoptive cell therapy	93
Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models	93
Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration	93
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C	93
Inhibiting endothelial Rhoj blocks profibrotic vascular intussusception and angiocrine factors to sustain lung regeneration	92
Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer	92
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies	91
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice	91
CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington’s disease	90
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting	90
Dysregulation of zebrin-II cell subtypes in the cerebellum is a shared feature across polyglutamine ataxia mouse models and patients	89
The SGLT2 inhibitor dapagliflozin improves kidney function in glycogen storage disease XI	89
Evolution of inflammation and immunity in a dengue virus 1 human infection model	88
G6PC2 controls glucagon secretion by defining the set point for glucose in pancreatic α cells	88
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome	88
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B.1.1.529) in England	88
Guanosine diphosphate–mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer	87
Targeting KDM4 for treating PAX3-FOXO1–driven alveolar rhabdomyosarcoma	87
Swiss public health measures associated with reduced SARS-CoV-2 transmission using genome data	86
No tolerance for Pseudomonas in lung transplants	86
A genetically engineered Plasmodium falciparum parasite vaccine provides protection from controlled human malaria infection	86
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env	85
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis	84
Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors	84
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury	83
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism	83
A self-amplifying loop of YAP and SHH drives formation and expansion of heterotopic ossification	82
A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage	82
Erratum for the Research Article “Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia” by R. Sartori et al .	81
Erratum for the Review “Insights into dengue immunity from vaccine trials”	81
Symptoms after Lyme disease: What’s past is prologue	81
Erratum for the Research Article “Aberrant activation of m6A demethylase FTO renders HIF2α low/– clear cell renal cell carcinoma sensitive to BRD9 inhibitors” by C.	81
Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation	81
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease	80
Agonism of the glutamate receptor GluK2 suppresses dermal mast cell activation and cutaneous inflammation	78
Development of a fibrin-targeted theranostic for gastric cancer	78
Zinc prevents vaginal candidiasis by inhibiting expression of an inflammatory fungal protein	78
Natural killer cells promote neutrophil extracellular traps and restrain macular degeneration in mice	77
Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer	77
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure	77
Pan-caspase inhibition as a potential host-directed immunotherapy against MRSA and other bacterial skin infections	76
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment	76
CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis	76
Immune regulation of pain: Friend and foe	76
A nanofibrous encapsulation device for safe delivery of insulin-producing cells to treat type 1 diabetes	75
Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer	75
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia	75
Pathophysiology of Dyt1- Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction	73
Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease	73
Modeling the effect of vaccination on selection for antibiotic resistance in Streptococcus pneumonia e	73
Modeling genetic diseases in nonhuman primates through embryonic and germline modification: Considerations and challenges	72
The trillion dollar vaccine gap	72
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine	71
Skeletal muscle regeneration with robotic actuation–mediated clearance of neutrophils	71
Population-level implications of the Israeli booster campaign to curtail COVID-19 resurgence	71
Pancreatic islet-specific engineered T regs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models	71
Engineering CAR-T therapies for autoimmune disease and beyond	71
Macrophage depletion induces edema through release of matrix-degrading proteases and proteoglycan deposition	71
Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests	71
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice	70
Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics	70
ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy	70
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates	70
Human iPSC–liver organoid transplantation reduces fibrosis through immunomodulation	70
A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections	69
Translating diagnostics and drug delivery technologies to low-resource settings	69
In vivo gene immunotherapy for cancer	67
Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation	66
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML	66
Sustained fetal hemoglobin induction in vivo is achieved by BCL11A interference and coexpressed truncated erythropoietin receptor	65
Listeria delivers tetanus toxoid protein to pancreatic tumors and induces cancer cell death in mice	65
Visualization of exhaled breath metabolites reveals distinct diagnostic signatures for acute cardiorespiratory breathlessness	64
Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity	64
Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics	64
Polymer nanoparticles deliver mRNA to the lung for mucosal vaccination	64
Inhibition of METTL3 attenuates renal injury and inflammation by alleviating TAB3 m6A modifications via IGF2BP2-dependent mechanisms	64
Bone morphogenetic protein 9 is a candidate prognostic biomarker and host-directed therapy target for sepsis	64
Iron controls the development of airway hyperreactivity by regulating ILC2 metabolism and effector function	64

Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis	64
Hypoxia as a medicine	64
The path to venetoclax resistance is paved with mutations, metabolism, and more	63
Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library	63
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens	63
Delineating epileptogenic networks using brain imaging data and personalized modeling in drug-resistant epilepsy	63
Formyl peptide receptor 1 signaling potentiates inflammatory brain injury	63
A first-in-human study of the fibroblast activation protein–targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors	62
Glp1r-Lepr coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist	62
Expression of the mono-ADP-ribosyltransferase ART1 by tumor cells mediates immune resistance in non–small cell lung cancer	61
Type 2–polarized memory B cells hold allergen-specific IgE memory	61
Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies	61
MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation	61
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging	61
A population of c-kit + IL-17A + ILC2s in sputum from individuals with severe asthma supports ILC2 to ILC3 trans-differentiation	61
Identification and characterization of human retinal stem cells capable of retinal regeneration	61
Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer’s disease	60
Exercise-induced piezoelectric stimulation for cartilage regeneration in rabbits	60
Schwann cells in the subcutaneous adipose tissue have neurogenic potential and can be used for regenerative therapies	60
Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy	60
Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity	59
Epicardial differentiation drives fibro-fatty remodeling in arrhythmogenic cardiomyopathy	59
Treatment of a genetic brain disease by CNS-wide microglia replacement	59
An integrated isothermal nucleic acid amplification test to detect HPV16 and HPV18 DNA in resource-limited settings	59
Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models	59
Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in BRCA1 or BRCA2	58
The gut microbiota posttranslationally modifies IgA1 in autoimmune glomerulonephritis	58
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency	58
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell–dependent regression of glioblastoma	58
Dendrimer nanotherapy for severe COVID-19 attenuates inflammation and neurological injury markers and improves outcomes in a phase2a clinical trial	57
Intervertebral disc human nucleus pulposus cells associated with back pain trigger neurite outgrowth in vitro and pain behaviors in rats	57
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery	57
cIAP1/2 antagonism eliminates MHC class I–negative tumors through T cell–dependent reprogramming of mononuclear phagocytes	57
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair	57
Neutralization of NET-associated human ARG1 enhances cancer immunotherapy	57
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo	57
Metaflammation in obesity and its therapeutic targeting	57
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies	57
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts	56
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q	56
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease	56
Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming	55
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease	55
Antigenic distance between primary and secondary dengue infections correlates with disease risk	55
Targeting GOLPH3L improves glioblastoma radiotherapy by regulating STING-NLRP3–mediated tumor immune microenvironment reprogramming	55
Tumor-associated NK cells drive MDSC-mediated tumor immune tolerance through the IL-6/STAT3 axis	55
Inhibiting mechanotransduction prevents scarring and yields regeneration in a large animal model	54
The pentameric complex is not required for congenital CMV transmission in seronegative rhesus macaques	54
β cell dedifferentiation, the underlying mechanism of diabetes in Wolfram syndrome	54
A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis	54
Enabling precision monitoring of psoriasis treatment by optoacoustic mesoscopy	54
Primary exposure to Zika virus is linked with increased risk of symptomatic dengue virus infection with serotypes 2, 3, and 4, but not 1	53
Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models	53
A human orthogonal IL-2 and IL-2Rβ system enhances CAR T cell expansion and antitumor activity in a murine model of leukemia	53
A portable magnetofluidic platform for detecting sexually transmitted infections and antimicrobial susceptibility	53
Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain	53
Enterococcal bacteremia in mice is prevented by oral administration of probiotic Bacillus spores	52
CAR T cells based on fully human T cell receptor–mimetic antibodies exhibit potent antitumor activity in vivo	52
Axial alignment is a critical regulator of knee osteoarthritis	52
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern	52
A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories	51
Principles of gait encoding in the subthalamic nucleus of people with Parkinson’s disease	51
Erratum for Research Article “Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents” by I. Llorente et al	51
A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury	51
Zoonotic mosquito-borne arboviruses: Spillover, spillback, and realistic mitigation strategies	51
Erratum for the Research Article “Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI” by X. Yu et al .	51
Early detection of pancreatic cancer by a high-throughput protease-activated nanosensor assay	51
Heterotypic immunity from prior SARS-CoV-2 infection but not COVID-19 vaccination associates with lower endemic coronavirus incidence	51
Backyard zoonoses: The roles of companion animals and peri-domestic wildlife	51
CD154 blockade effectively controls antibody-mediated rejection in highly sensitized nonhuman primate kidney transplant recipients	50
Glutamic-pyruvic transaminase 1 deficiency–mediated metabolic reprogramming facilitates colorectal adenoma-carcinoma progression	50
Integrating the gut microbiome and pharmacology	49
Closed-loop stimulation using a multiregion brain-machine interface has analgesic effects in rodents	49
Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects	49
Functional impairment of CD19 + CD24 hi CD38 hi B cells in neuromyelitis optica spectrum disord	49
Tissue-resident memory CD8 + T cells cooperate with CD4 + T cells to drive compartmentalized immunopathology in the CNS	49
Topical JAK inhibition ameliorates EGFR inhibitor–induced rash in rodents and humans	49
Toll-like receptor 4–mediated enteric glia loss is critical for the development of necrotizing enterocolitis	48
Next-generation CAR T cell therapies for glioblastoma	48
An orthogonal IL-2 and IL-2Rβ system drives persistence and activation of CAR T cells and clearance of bulky lymphoma	48
USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice	48
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy	48
Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans	48
Treatment of experimental anthrax with pegylated circularly permuted capsule depolymerase	48
Measuring anti-islet autoimmunity in mouse and human by profiling peripheral blood antigen-specific CD4 T cells	48
Erratum for the Research Article “Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers,” by C. Sun et al	47
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology	47
GPR177 in A-fiber sensory neurons drives diabetic neuropathic pain via WNT-mediated TRPV1 activation	47
Erratum for the Research Article “CRISPR-enhanced engineering of therapy-sensitive cancer cells for self-targeting of primary and metastatic tumors” by C. Reinshagen et al	47
Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis	47
TREM1 activation of myeloid cells promotes antitumor immunity	47
Monoclonal antibodies that block Roundabout 1 and 2 signaling target pathological ocular neovascularization through myeloid cells	47
Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer	46
Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe	46
Identification of a small-molecule Tim-3 inhibitor to potentiate T cell–mediated antitumor immunotherapy in preclinical mouse models	46