Science Translational Medicine

Papers
(The TQCC of Science Translational Medicine is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Stronger regulation of AI in biomedicine496
A tale of two cells: Regulatory T cell–microglia cross-talk in the ischemic brain400
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging313
Antigenic distance between primary and secondary dengue infections correlates with disease risk290
Combination bezafibrate and nivolumab treatment of patients with advanced non–small cell lung cancer236
Evolution of inflammation and immunity in a dengue virus 1 human infection model221
Germline-encoded recognition of peanut underlies development of convergent antibodies in humans213
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair202
Integrated analysis of blood DNA methylation, genetic variants, circulating proteins, microRNAs, and kidney failure in type 1 diabetes202
Transcriptome-based identification of tumor-reactive and bystander CD8 + T cell receptor clonotypes in human pancreatic cancer202
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome200
A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens191
Characterization of the SARS-CoV-2 B.1.621 (Mu) variant190
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer190
Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation187
The rapid replacement of the SARS-CoV-2 Delta variant by Omicron (B.1.1.529) in England187
Increased brain microvascular hemoglobin concentrations in children with cerebral malaria186
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting185
In vivo gene immunotherapy for cancer180
SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery178
Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice176
Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans167
Erratum for the Research Article: “Selectins impair regulatory T cell function and contribute to systemic lupus erythematosus pathogenesis” by M. Scherlinger, V. Guillotin, I. Douchet, P. Vacher, A. B162
Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection159
Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancer155
A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine147
SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8 + T cells143
Advancing beyond the twists and turns of T cell exhaustion in cancer142
Metabolic reprogramming of skeletal muscle by resident macrophages points to CSF1R inhibitors as muscular dystrophy therapeutics142
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment142
Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms142
Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment141
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies141
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia135
Point-of-care diagnostic tests for tuberculosis disease134
A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer134
A first-in-human study of the fibroblast activation protein–targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors131
Engineering CAR-T therapies for autoimmune disease and beyond128
Systemic administration of an RNA binding and cell-penetrating antibody targets therapeutic RNA to multiple mouse models of cancer125
A risk model for digital breast tomosynthesis to predict breast cancer and guide clinical care125
Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans124
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice123
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry122
The pancreatic clock is a key determinant of pancreatic fibrosis progression and exocrine dysfunction122
Erratum for the Research Article: “The Role of Dimethylarginine Dimethylaminohydrolase in Idiopathic Pulmonary Fibrosis” by S. S. Pullamsetti, R. Savai, R. Dumitrascu, B. K. Dahal, J. Wilhelm, M. Koni121
Rapid closure and hemostasis of ruptured soft tissues using a modified human tropoelastin-based sealant in preclinical models119
BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease117
Improved control of a prosthetic limb by surgically creating electro-neuromuscular constructs with implanted electrodes116
Development and preclinical validation of 2-deoxy 2-[ 18 F]fluorocellobiose as an Aspergillus -specific PET tracer115
A human histidyl-tRNA synthetase splice variant therapeutic targets NRP2 to resolve lung inflammation and fibrosis113
NAD + precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction112
TREM1 activation of myeloid cells promotes antitumor immunity111
Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons110
Integrating the gut microbiome and pharmacology110
4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2 -encephalopathy109
Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors109
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation108
Hepatocyte CYR61 polarizes profibrotic macrophages to orchestrate NASH fibrosis108
Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas107
The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC–derived sensory neurons107
Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe106
Repeated COVID-19 mRNA-based vaccination contributes to SARS-CoV-2 neutralizing antibody responses in the mucosa105
Translating insights into therapies for Long Covid105
Molecular hallmarks of hydrocephalus103
Next-generation CAR T cell therapies for glioblastoma103
MEK1/2 inhibitors suppress pathological α-synuclein and neurotoxicity in cell models and a humanized mouse model of Parkinson’s disease103
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia103
Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection103
Nonlesional lupus skin contributes to inflammatory education of myeloid cells and primes for cutaneous inflammation102
The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron101
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting100
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager100
Targeting AKR1B1 inhibits glutathione de novo synthesis to overcome acquired resistance to EGFR-targeted therapy in lung cancer99
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy99
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models98
Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)98
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease97
Myeloid MAS–driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers95
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort95
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment94
Anti-merozoite antibodies induce natural killer cell effector function and are associated with immunity against malaria94
Postoperative adhesions are abrogated by a sustained-release anti-JUN therapeutic in preclinical models94
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria93
Harnessing regulatory T cells to establish immune tolerance92
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice92
Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors91
Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease91
Repeated Plasmodium falciparum infection in humans drives the clonal expansion of an adaptive γδ T cell repertoire91
Mitochondrial augmentation of hematopoietic stem cells in children with single large-scale mitochondrial DNA deletion syndromes91
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific T H 1 response with a diverse TCR repertoire90
Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer90
Innate PD-L1 limits T cell–mediated adipose tissue inflammation and ameliorates diet-induced obesity90
T cell receptor precision editing of regulatory T cells for celiac disease89
Wastewater surveillance facilitates climate change–resilient pathogen monitoring89
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months88
Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis88
Diet shapes the metabolite profile in the intact human ileum, which affects PYY release88
Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model87
The adenosine analog prodrug ATV006 is orally bioavailable and has preclinical efficacy against parental SARS-CoV-2 and variants87
Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial87
A nose for tau85
Obesity and lifespan, a complex tango84
Farnesoid X receptor antagonizes macrophage-dependent licensing of effector T lymphocytes and progression of sclerosing cholangitis84
Short-course combination treatment for experimental chronic Chagas disease84
Assessment of cholesterol homeostasis in the living human brain83
Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration83
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders82
CD23 + IgG1 + memory B cells are poised to switch to pathogenic IgE production in food allergy81
Sirtuin 6 is required for the integrated stress response and resistance to inhibition of transcriptional cyclin-dependent kinases81
A systems approach points to a therapeutic role for retinoids in asparaginase-associated pancreatitis81
Metabolic surgery reduces CRC disease progression through circulating bile acid diversion80
Erratum for the Research Article “A functional identification platform reveals frequent, spontaneous neoantigen-specific T cell responses in patients with cancer” by A. M. Miller et al<79
Immune responses to gut bacteria associated with time to diagnosis and clinical response to T cell–directed therapy for type 1 diabetes prevention79
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice79
Collagen V regulates renal function after kidney injury and can be pharmacologically targeted to enhance kidney repair in mice79
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-1979
Green light analgesia in mice is mediated by visual activation of enkephalinergic neurons in the ventrolateral geniculate nucleus79
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection78
Sex, lean body mass, and cardiac performance78
A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models78
IgE in allergy: It takes two77
Treatment with ROS detoxifying gold quantum clusters alleviates the functional decline in a mouse model of Friedreich ataxia77
Synthetic biology–driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer77
Targeting cytokines in inflammatory bowel disease76
Piplartine attenuates aminoglycoside-induced TRPV1 activity and protects from hearing loss in mice76
MicroRNA-142-3p shuttling in extracellular vesicles marks regulatory T cell dysfunction in multiple sclerosis76
A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis75
Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia75
T STEM -like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models75
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice74
An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor74
A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria74
Oral mucosal breaks trigger anti-citrullinated bacterial and human protein antibody responses in rheumatoid arthritis74
Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing73
NFIA regulates articular chondrocyte fatty acid metabolism and joint homeostasis72
A cell-penetrant peptide blocking C9ORF72 -repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins72
Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair72
Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection72
Tissue-resident CD8 + T cells drive compartmentalized and chronic autoimmune damage against CNS neurons72
Simultaneous analysis of mutations and methylations in circulating cell-free DNA for hepatocellular carcinoma detection71
Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation71
Tumor-associated fibrosis impairs immune surveillance and response to immune checkpoint blockade in non–small cell lung cancer70
Microbiome alteration via fecal microbiota transplantation is effective for refractory immune checkpoint inhibitor–induced colitis70
MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases70
An influenza H1 hemagglutinin stem-only immunogen elicits a broadly cross-reactive B cell response in humans69
Albumin nanoparticle containing a PI3Kγ inhibitor and paclitaxel in combination with α-PD1 induces tumor remission of breast cancer in mice69
A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice69
Targeting ryanodine receptor type 2 to mitigate chemotherapy-induced neurocognitive impairments in mice69
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell–mediated antitumor immune response68
Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers68
Comment on “A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk”68
Translating the evolving molecular landscape of tumors to biomarkers of response for cancer immunotherapy68
Preexisting immunity to the 2009 pandemic H1N1 virus reduces susceptibility to H5N1 infection and disease in ferrets68
Seeking satiety: From signals to solutions67
In vivo Bruton’s tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis67
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease67
Erratum for the Research Article “Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4” by Y. Ren et al .67
Spatial genomics: Mapping the landscape of fibrosis67
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers67
Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics66
Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-1966
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis65
Repeated Omicron exposures redirect SARS-CoV-2–specific memory B cell evolution toward the latest variants65
Preclinical efficacy and pharmacokinetics of an RNA-encoded T cell–engaging bispecific antibody targeting human claudin 665
Resident microbes shape the vaginal epithelial glycan landscape65
Human OX40L–CAR-T regs target activated antigen-presenting cells and control T cell alloreactivity65
Neuroinflammation: An astrocyte perspective65
A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma65
Erratum for the Research Article: “Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses” by E. A. Bordt, L. L. Shook, C. Atyeo, K. M. Pullen, R. M. De Guzman, M.-C. Mein64
Delivery of therapeutic carbon monoxide by gas-entrapping materials64
Blocking common γ chain cytokine signaling ameliorates T cell–mediated pathogenesis in disease models64
An AAV gene therapy computes over multiple cellular inputs to enable precise targeting of multifocal hepatocellular carcinoma in mice62
Dynamic PET-facilitated modeling and high-dose rifampin regimens for Staphylococcus aureus orthopedic implant–associated infections62
Erratum for the Research Article “Platelet-derived growth factor C signaling is a potential therapeutic target for radiation proctopathy” by W. Lu et al .62
Genipin rescues developmental and degenerative defects in familial dysautonomia models and accelerates axon regeneration62
Interleukin-2–based therapies in cancer62
New government drug repurposing programs: Opportunities and uncertainties61
Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models61
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models61
A germline SNP in BRMS1 predisposes patients with lung adenocarcinoma to metastasis and can be ameliorated by targeting c-fos61
Expression of the excitatory opsin ChRERα can be traced longitudinally in rat and nonhuman primate brains with PET imaging61
Identifying and targeting the Achilles heel of a recalcitrant cancer60
Gastric dysfunction in patients with chronic nausea and vomiting syndromes defined by a noninvasive gastric mapping device60
Inhibition of VEGF binding to neuropilin-2 enhances chemosensitivity and inhibits metastasis in triple-negative breast cancer60
Targeting Src reactivates pyroptosis to reverse chemoresistance in lung and pancreatic cancer models60
Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer60
Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice60
NF-κB perturbation reveals unique immunomodulatory functions in Prx1 + fibroblasts that promote development of atopic dermatitis59
Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer’s disease59
Allergy: Mechanistic insights into new methods of prevention and therapy59
Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease59
Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases59
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection59
Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology58
Neuromodulation using ultra low frequency current waveform reversibly blocks axonal conduction and chronic pain58
Gut microbiome composition may be an indicator of preclinical Alzheimer’s disease58
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due toTTNmutations58
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy57
Targeting SIRT2 induces MLH1 deficiency and boosts antitumor immunity in preclinical colorectal cancer models57
Response to Comment on “Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases”57
Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unit57
Learning CNS immunopathology from therapeutic interventions56
Donor-derived regulatory dendritic cell infusion modulates effector CD8+T cell and NK cell responses after liver transplantation56
Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis55
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase55
A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury55
Provocateurs of autoimmunity within the gut microbiota54
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson’s disease54
Chemogenetics identifies separate area 25 brain circuits involved in anhedonia and anxiety in marmosets54
Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected54
A homologous or variant booster vaccine after Ad26.COV2.S immunization enhances SARS-CoV-2–specific immune responses in rhesus macaques54
Vaccination with different group 2 influenza subtypes alters epitope targeting and breadth of hemagglutinin stem–specific human B cells54
Where do the pathogens that cause surgical site infections come from?53
Erratum for the Research Article “Boosting systemic absorption of peptides with a bioinspired buccal-stretching patch,” by Z. Luo et al .53
Protein kinase Cι mediates immunosuppression in lung adenocarcinoma53
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model52
Alpelisib administration reduced lymphatic malformations in a mouse model and in patients52
Predicting the next round of drugs for Medicare price negotiation52
T cell responses to SARS-CoV-2 infection and vaccination are elevated in B cell deficiency and reduce risk of severe COVID-1952
Precise genomic editing of pathogenic mutations in RBM20 rescues dilated cardiomyopathy52
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy52
Response to comment on “Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics”52
Neuronal population activity in the olivocerebellum encodes the frequency of essential tremor in mice and patients52
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes51
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses51
GABABreceptor modulation of visual sensory processing in adults with and without autism spectrum disorder51
Activation and antitumor immunity of CD8 + T cells are supported by the glucose transporter GLUT10 and disrupted by lactic acid51
Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer51
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human51
Erratum for the Research Article “Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia” by R. Sartori et al .50
Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis50
Triple knockdown of CD11a , CD49d , and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity50
The protein kinase C modulator bryostatin-1 therapeutically targets microglia to attenuate neuroinflammation and promote remyelination50
Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss50
Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria50
Population-level implications of the Israeli booster campaign to curtail COVID-19 resurgence50
Keratinocytes: From passive targets to active mediators of systemic autoimmunity50
Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo50
An anti-mycobacterial conjugated oligoelectrolyte effective against Mycobacterium abscessus50
Pathophysiology of Dyt1- Tor1a dystonia in mice is mediated by spinal neural circuit dysfunction49
Hemodynamic evaluation of biomaterial-based surgery for Tetralogy of Fallot using a biorobotic heart, in silico, and ovine models49
DeepHeme, a high-performance, generalizable deep ensemble for bone marrow morphometry and hematologic diagnosis49
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease49
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers49
Transient anti-interferon autoantibodies in the airways are associated with recovery from COVID-1949
Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis49
The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells49
An identity crisis for lung cancer cells48
A new chapter in lipid signaling and kidney fibrosis48
Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation48
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