World Journal of Stem Cells

Article	Citations
Stem cell therapy for Alzheimer's disease	77
Mesenchymal stem cells secretome: The cornerstone of cell-free regenerative medicine	73
Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine	52
Human embryonic stem cell-derived mesenchymal stem cells improved premature ovarian failure	46
Multifaceted p21 in carcinogenesis, stemness of tumor and tumor therapy	44
Energy metabolism in cancer stem cells	41
Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells	39
Therapeutic potential of periodontal ligament stem cells	35
Mesenchymal stem cell-derived small extracellular vesicles in the treatment of human diseases: Progress and prospect	35
Bone marrow mesenchymal stem cells induce M2 microglia polarization through PDGF-AA/MANF signaling	34
Effect of metformin on stem cells: Molecular mechanism and clinical prospect	32
Ability of human umbilical cord mesenchymal stem cells to repair chemotherapy-induced premature ovarian failure	31
Dental stem cells: The role of biomaterials and scaffolds in developing novel therapeutic strategies	31
Advances in treatment of neurodegenerative diseases: Perspectives for combination of stem cells with neurotrophic factors	31
Photodynamic therapy regulates fate of cancer stem cells through reactive oxygen species	30
High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration	28
Potential therapeutic applications of mesenchymal stem cells for the treatment of eye diseases	27
Role of hypoxia preconditioning in therapeutic potential of mesenchymal stem-cell-derived extracellular vesicles	26
Multifunctional role of microRNAs in mesenchymal stem cell-derived exosomes in treatment of diseases	26
Human hair follicle-derived mesenchymal stem cells: Isolation, expansion, and differentiation	25
Pericyte-like differentiation of human adipose-derived mesenchymal stem cells: An in vitro study	25
Stem cell therapies in tendon-bone healing	24
Mesenchymal stem cells as living anti-inflammatory therapy for COVID-19 related acute respiratory distress syndrome	24
SOX transcription factors and glioma stem cells: Choosing between stemness and differentiation	24
Stem cell quiescence and its clinical relevance	24

Approaches to promoting bone marrow mesenchymal stem cell osteogenesis on orthopedic implant surface	24
Exosomes derived from stem cells as an emerging therapeutic strategy for intervertebral disc degeneration	24
Role and mechanism of neural stem cells of the subventricular zone in glioblastoma	23
Senescent mesenchymal stem/stromal cells and restoring their cellular functions	23
Role of mesenchymal stem cell derived extracellular vesicles in autoimmunity: A systematic review	23
Urolithin a alleviates oxidative stress-induced senescence in nucleus pulposus-derived mesenchymal stem cells through SIRT1/PGC-1α pathway	22
Inflammatory bowel disease: Therapeutic limitations and prospective of the stem cell therapy	22
Role of stem cell therapies in treating chronic wounds: A systematic review	22
Neural stem cell therapy for brain disease	21
Exosomal microRNAs from mesenchymal stem/stromal cells: Biology and applications in neuroprotection	21
Programmed cell death in stem cell-based therapy: Mechanisms and clinical applications	20
Urine-derived stem/progenitor cells: A focus on their characterization and potential	20
Adipose-derived stem cells: Pathophysiologic implications vs therapeutic potential in systemic sclerosis	20
Mesenchymal stem cell-derived exosomes: A novel and potential remedy for cutaneous wound healing and regeneration	20
Effects of storage media, supplements and cryopreservation methods on quality of stem cells	19
Human umbilical cord derived mesenchymal stem cells in peripheral nerve regeneration	19
Current advances of stem cell-based therapy for kidney diseases	19
Mesenchymal stromal cells as potential immunomodulatory players in severe acute respiratory distress syndrome induced by SARS-CoV-2 infection	19
Application of mesenchymal stem cells derived from human pluripotent stem cells in regenerative medicine	18
Safety of menstrual blood-derived stromal cell transplantation in treatment of intrauterine adhesion	18
Umbilical cord-derived mesenchymal stem cells preconditioned with isorhamnetin: potential therapy for burn wounds	18
Biological, chemical and mechanical factors regulating migration and homing of mesenchymal stem cells	18
Nanofat: A therapeutic paradigm in regenerative medicine	18
Role of platelets and breast cancer stem cells in metastasis	18
Human mesenchymal stem cells derived from umbilical cord and bone marrow exert immunomodulatory effects in different mechanisms	18
Translational products of adipose tissue-derived mesenchymal stem cells: Bench to bedside applications	18
Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells	18
Functional maturation of immature β cells: A roadblock for stem cell therapy for type 1 diabetes	17
Therapeutic prospects of mesenchymal stem/stromal cells in COVID-19 associated pulmonary diseases: From bench to bedside	17
Epigenetic regulation of dental pulp stem cells and its potential in regenerative endodontics	17
Differences and similarities between mesenchymal stem cell and endothelial progenitor cell immunoregulatory properties against T cells	17
Molecular modulation of autophagy: New venture to target resistant cancer stem cells	16
Effects of immune cells on mesenchymal stem cells during fracture healing	16
Defining lung cancer stem cells exosomal payload of miRNAs in clinical perspective	16
Bone marrow mesenchymal stem cell therapy regulates gut microbiota to improve post-stroke neurological function recovery in rats	16
Neurotrophic effects of dental pulp stem cells in repair of peripheral nerve after crush injury	16
Decellularized adipose matrix provides an inductive microenvironment for stem cells in tissue regeneration	16
Role of the CXCR4-SDF1-HMGB1 pathway in the directional migration of cells and regeneration of affected organs	16
Recent trends in stem cell-based therapies and applications of artificial intelligence in regenerative medicine	16
Hunting down the dominating subclone of cancer stem cells as a potential new therapeutic target in multiple myeloma: An artificial intelligence perspective	16
Perspectives of pluripotent stem cells in livestock	15
Strategies to improve regenerative potential of mesenchymal stem cells	15
Stem cell therapy for COVID-19 and other respiratory diseases: Global trends of clinical trials	15
Perspectives on mesenchymal stem/progenitor cells and their derivates as potential therapies for lung damage caused by COVID-19	15
Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem cells from induced pluripotent stem cells	15
Overview of noncoding RNAs involved in the osteogenic differentiation of periodontal ligament stem cells	15
Transcription regulators differentiate mesenchymal stem cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration	14
Modulating poststroke inflammatory mechanisms: Novel aspects of mesenchymal stem cells, extracellular vesicles and microglia	14
Adipose-derived stem cell therapy shows promising results for secondary lymphedema	14
Insights of stem cell-based endogenous repair of intervertebral disc degeneration	14

DNA methylation and demethylation link the properties of mesenchymal stem cells: Regeneration and immunomodulation	14
Mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles: Potential roles in rheumatic diseases	14
Stem cell therapy for heart failure: Medical breakthrough, or dead end?	14
Lipid droplets as metabolic determinants for stemness and chemoresistance in cancer	14
Modified mesenchymal stem cells in cancer therapy: A smart weapon requiring upgrades for wider clinical applications	14
Influence of donor age on the differentiation and division capacity of human adipose-derived stem cells	14
Stem cell homing, tracking and therapeutic efficiency evaluation for stroke treatment using nanoparticles: A systematic review	14
Acupuncture accelerates neural regeneration and synaptophysin production after neural stem cells transplantation in mice	14
Mechanotransduction of stem cells for tendon repair	13
First immunohistochemical evidence of human tendon repair following stem cell injection: A case report and review of literature	13
Potential of transposon-mediated cellular reprogramming towards cell-based therapies	13
Mechanisms of action of neuropeptide Y on stem cells and its potential applications in orthopaedic disorders	13
Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation/differentiation	13
ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells	13
Review of the potential of mesenchymal stem cells for the treatment of infectious diseases	13
Mesenchymal stem cells as a potential therapeutic tool to cure cognitive impairment caused by neuroinflammation	13
Multidifferentiation potential of dental-derived stem cells	13
Calcium channels and their role in regenerative medicine	12
Advance in metabolism and target therapy in breast cancer stem cells	12
Epigenetic regulation of autophagy: A key modification in cancer cells and cancer stem cells	12
Stem cell therapy in ocular pathologies in the past 20 years	12
Vitamin D and calcium signaling in epidermal stem cells and their regeneration	12
6-gingerol protects nucleus pulposus-derived mesenchymal stem cells from oxidative injury by activating autophagy	12
Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes	12
Bone marrow-derived products: A classification proposal – bone marrow aspirate, bone marrow aspirate concentrate or hybrid?	12
Pancreatic β cell regeneration induced by clinical and preclinical agents	12
Stem cell therapy and diabetic erectile dysfunction: A critical review	12
Age and genotype dependent erythropoietin protection in COVID-19	11
Application and prospect of adipose stem cell transplantation in treating lymphedema	11
Stem cell therapies in cardiac diseases: Current status and future possibilities	11
Effects of shear stress on differentiation of stem cells into endothelial cells	11
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway	11
Stem cell-based therapies for fertility preservation in males: Current status and future prospects	11
Dental stem cell-conditioned medium for tissue regeneration: Optimization of production and storage	10
Recent advances of single-cell RNA sequencing technology in mesenchymal stem cell research	10
Current understanding of mesenchymal stem cells in liver diseases	10
Antler stem cells and their potential in wound healing and bone regeneration	10
Understanding cellular and molecular mechanisms of pathogenesis of diabetic tendinopathy	10
Autophagy in fate determination of mesenchymal stem cells and bone remodeling	10
Inflammatory niche: Mesenchymal stromal cell priming by soluble mediators	10
Cardiac stem cells: Current knowledge and future prospects	10
Noninvasive in vivo cell tracking using molecular imaging: A useful tool for developing mesenchymal stem cell-based cancer treatment	9
Creating rat hepatocyte organoid as an in vitro model for drug testing	9
Novel insights for improving the therapeutic safety and efficiency of mesenchymal stromal cells	9
Current evidence on potential of adipose derived stem cells to enhance bone regeneration and future projection	9
New insight into dental epithelial stem cells: Identification, regulation, and function in tooth homeostasis and repair	9
Effects of normobaric cyclic hypoxia exposure on mesenchymal stem-cell differentiation–pilot study on bone parameters in elderly	9
Anti-fibrotic effect of adipose-derived stem cells on fibrotic scars	9
Stem cell-based approaches: Possible route to hearing restoration?	9
Platelet-rich plasma vs bone marrow aspirate concentrate: An overview of mechanisms of action and orthobiologic synergistic effects	9
Heat shock protein 20 promotes sirtuin 1-dependent cell proliferation in induced pluripotent stem cells	8
Stem cell therapy: A paradigm shift in breast cancer treatment	8
Alternative models of cancer stem cells: The stemness phenotype model, 10 years later	8
Hypoxia-inducible factor-1α–mediated upregulation of CD99 promotes the proliferation of placental mesenchymal stem cells by regulating ERK1/2	8
Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases	8
Minibrain-related kinase/dual-specificity tyrosine-regulated kinase 1B implication in stem/cancer stem cells biology	8
Orthobiologics in the treatment of hip disorders	7
Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells	7
Molecular mechanism of therapeutic approaches for human gastric cancer stem cells	7
Current and future uses of skeletal stem cells for bone regeneration	7
Epigenetic modulators for brain cancer stem cells: Implications for anticancer treatment	7
Why stem/progenitor cells lose their regenerative potential	7
Empty nose syndrome pathogenesis and cell-based biotechnology products as a new option for treatment	7
Patient-specific induced pluripotent stem cells as “disease-in-a-dish” models for inherited cardiomyopathies and channelopathies – 15 years of research	7
Insulin resistance in diabetes: The promise of using induced pluripotent stem cell technology	7
Mass acquisition of human periodontal ligament stem cells	7
Immunotherapy against programmed death-1/programmed death ligand 1 in hepatocellular carcinoma: Importance of molecular variations, cellular heterogeneity, and cancer stem cells	7
Proteomic profiling of various human dental stem cells - a systematic review	7
Intratracheal administration of umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced multi-organ injury via heme oxygenase-1 and JAK/STAT pathways	7
Mesenchymal stem cells for enhancing biological healing after meniscal injuries	6
Retina stem cells, hopes and obstacles	6
Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications	6
Factors affecting osteogenesis and chondrogenic differentiation of mesenchymal stem cells in osteoarthritis	6
miR-3682-3p directly targets FOXO3 and stimulates tumor stemness in hepatocellular carcinoma via a positive feedback loop involving FOXO3/PI3K/AKT/c-Myc	6
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells	6
Cytotoxicity of nonylphenol on spermatogonial stem cells via phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin pathway	6
Human embryonic stem cells as anin vitromodel for studying developmental origins of type 2 diabetes	6
Priming strategies for controlling stem cell fate: Applications and challenges in dental tissue regeneration	6
Proliferation and tenogenic differentiation of bone marrow mesenchymal stem cells in a porous collagen sponge scaffold	6
Medical, ethical, and legal aspects of hematopoietic stem cell transplantation for Crohn’s disease in Brazil	6

Application of cattle placental stem cells for treating ovarian follicular cyst	6
Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles	6
Low complexity domains, condensates, and stem cell pluripotency	6
Overview of nutritional approach in hematopoietic stem cell transplantation: COVID-19 update	6
Vascularization and osteogenesis in ectopically implanted bone tissue-engineered constructs with endothelial and osteogenic differentiated adipose-derived stem cells	6
Effect of glycyrrhizic acid and 18β-glycyrrhetinic acid on the differentiation of human umbilical cord-mesenchymal stem cells into hepatocytes	6
Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: Phase I study	6
Regulation of the mesenchymal stem cell fate by interleukin-17: Implications in osteogenic differentiation	5
Growing and aging of hematopoietic stem cells	5
Spinal cord injury regeneration using autologous bone marrow-derived neurocytes and rat embryonic stem cells: A comparative study in rats	5
Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy	5
Abnormal lipid synthesis as a therapeutic target for cancer stem cells	5
Different priming strategies improve distinct therapeutic capabilities of mesenchymal stromal/stem cells: Potential implications for their clinical use	5
Treatment of acute ischemic stroke by minimally manipulated umbilical cord-derived mesenchymal stem cells transplantation: A case report	5
Stem cell-derived biofactors fight against coronavirus infection	5
Regulating the fate of stem cells for regenerating the intervertebral disc degeneration	5
Reporter gene systems for the identification and characterization of cancer stem cells	5
Clinical trials using dental stem cells: 2022 update	5
Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and its emerging use	5
Cell transplantation therapies for spinal cord injury focusing on bone marrow mesenchymal stem cells: Advances and challenges	5
Targeting mesenchymal stem cell therapy for severe pneumonia patients	4
Considerations for the clinical use of stem cells in genitourinary regenerative medicine	4
Strategies for treating oesophageal diseases with stem cells	4
Neural stem cells for Parkinson’s disease management: Challenges, nanobased support, and prospects	4
Alternative RNA splicing in stem cells and cancer stem cells: Importance of transcript-based expression analysis	4
Advances of nanotechnology applied to cancer stem cells	4
Disease modifying treatment of spinal cord injury with directly reprogrammed neural precursor cells in non-human primates	4
Inter-regulatory role of microRNAs in interaction between viruses and stem cells	4
Regulators of liver cancer stem cells	4
Communication between bone marrow mesenchymal stem cells and multiple myeloma cells: Impact on disease progression	4
Acquired aplastic anemia: Is bystander insult to autologous hematopoiesis driven by immune surveillance against malignant cells?	4
Correlation between amino acid metabolism and self-renewal of cancer stem cells: Perspectives in cancer therapy	4
Mesenchymal stem cells and COVID-19: What they do and what they can do	4
Still 'dwelling in the possibility' - critical update on stem cell therapy for acute on chronic liver failure	4
Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts	4
Review of operative considerations in spinal cord stem cell therapy	4
Advanced glycation end productions and tendon stem/progenitor cells in pathogenesis of diabetic tendinopathy	4
Application of adipose-derived stem cells in treating fibrosis	4
Treatment of syringomyelia using uncultured umbilical cord mesenchymal stem cells: A case report and review of literature	4
Induced pluripotent stem cells as suitable sensors for fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome	4
Dental mesenchymal stromal/stem cells in different microenvironments— implications in regenerative therapy	4
Adult neural stem cells and schizophrenia	4
Roles of mitochondrial unfolded protein response in mammalian stem cells	4
Application of exosome-derived noncoding RNAs in bone regeneration: Opportunities and challenges	4
Isolation and characterization of mesenchymal stem cells in orthopaedics and the emergence of compact bone mesenchymal stem cells as a promising surgical adjunct	4