World Journal of Stem Cells

Article	Citations
Stem cells and pain	73
Recombinant human thrombopoietin safety and efficacy in pediatric allogeneic hematopoietic stem cell transplantation: A cohort study	64
Application and prospects of high-throughput screening for in vitro neurogenesis	38
Combination of mesenchymal stem cells and three-dimensional collagen scaffold preserves ventricular remodeling in rat myocardial infarction model	36
Effects of exosomes from mesenchymal stem cells on functional recovery of a patient with total radial nerve injury: A pilot study	30
Stem cell-derived neural organoids as platforms to investigate glioblastoma invasion and migration: A systematic review	29
Insights into mitofusin-2 and endoplasmic reticulum stress regulation in adipose-derived mesenchymal stem cells senescence	28
Emerging role of mesenchymal stem cell-derived exosomes in the repair of acute kidney injury	25
MicroRNA-584-5p/RUNX family transcription factor 2 axis mediates hypoxia-induced osteogenic differentiation of periosteal stem cells	24
Human retinal secretome: A cross-link between mesenchymal and retinal cells	24
Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells	24
Wharton’s jelly mesenchymal stem cells: Future regenerative medicine for clinical applications in mitigation of radiation injury	24
Hurdles to overcome for mesenchymal stem cell translation from bench to bedside	23
Clinical trials using dental stem cells: 2022 update	23
Harnessing and honing mesenchymal stem/stromal cells for the amelioration of graft-versus-host disease	22
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study	22
Mesenchymal stem cell-derived extracellular vesicles: Pioneering the next generation of biomedical applications	22
Fibro-adipogenic progenitors prevent skeletal muscle degeneration at acute phase upon tendon rupture in a murine tibialis anterior tenotomy model	20
Collagen III combined with autologous adipose-derived mesenchymal stem cells accelerates burn wound healing in a rat model	20
Sinomenine promotes differentiation of induced pluripotent stem cells into immature dendritic cells with high induction of immune tolerance	18
Gut microbiota modulating intestinal stem cell differentiation	18
Post-translational modifications in osteogenic differentiation of oral-derived stem cells: Mechanisms and clinical implications	18
Biological scaffold as potential platforms for stem cells: Current development and applications in wound healing	18
Gamma-aminobutyric acid enhances miR-21-5p loading into adipose-derived stem cell extracellular vesicles to alleviate myocardial ischemia-reperfusion injury via TXNIP regulation	17
Exosomal delivery of GrpE-like 1 from synovial mesenchymal stem cells activates PINK1-mediated mitophagy for cartilage repair in osteoarthritis	17

MiR-21-5p-enriched exosomes from hiPSC-derived cardiomyocytes exhibit superior cardiac repair efficacy compared to hiPSC-derived exosomes in a murine MI model	17
Mechanisms of analgesic effect of mesenchymal stem cells in osteoarthritis pain	16
Interferon-γ priming enhances the therapeutic effects of menstrual blood-derived stromal cells in a mouse liver ischemia-reperfusion model	16
Exosomal miR-137-3p targets UBE3C to activate STAT3, promoting migration and differentiation into endometrial epithelial cell of human umbilical cord mesenchymal stem cells under hypoxia	15
Multiroute administration of Wharton’s jelly mesenchymal stem cells in chronic complete spinal cord injury: A phase I safety and feasibility study	15
Treatment of syringomyelia using uncultured umbilical cord mesenchymal stem cells: A case report and review of literature	15
Comparison of therapeutic potential of macrophage- or mesenchymal stem cell-derived exosomes in pancreatic cancer: An updated review	15
Tumor necrosis factor-α inhibition restores matrix formation by human adipose-derived stem cells in the late stage of chondrogenic differentiation	15
Patient-derived induced pluripotent stem cells with a MERTK mutation exhibit cell junction abnormalities and aberrant cellular differentiation potential	14
Current status and prospects of basic research and clinical application of mesenchymal stem cells in acute respiratory distress syndrome	14
Advancing mechanistic insights and clinical translation of exosomal miR-137-3p in endometrial regeneration	14
Mesenchymal stem/stromal cells as adjuvant therapy in COVID-19-associated acute lung injury and cytokine storm: Importance of cell identification	13
Novel developments in retinal regeneration: Advances and future outlooks in stem cell therapy	13
Mesenchymal stem cell exosomes enhance the development of hair follicle to ameliorate androgenetic alopecia	13
Banking of perinatal mesenchymal stem/stromal cells for stem cell-based personalized medicine over lifetime: Matters arising	13
Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications	13
Understanding and controlling the variables for advanced cell therapy	13
Extracellular vesicles: Emerged as a promising strategy for regenerative medicine	13
Therapeutic potential of mesenchymal stem cells in neurodegenerative diseases	13
O-linked β-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells	12
Innovative hydrogel delivery of bone marrow stromal cell-derived exosomes for enhanced bone healing	12
Effects of different concentrations of nicotinamide on hematopoietic stem cells cultured in vitro	12
Repetitive administration of cultured human CD34+ cells improve adenine-induced kidney injury in mice	12
Cell-free extracts from human fat tissue attenuate ischemic injury in cardiomyocytes in a murine model	12
Potential of ginsenoside Rg1 to treat aplastic anemia via mitogen activated protein kinase pathway in cyclophosphamide-induced myelosuppression mouse model	12
Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations	12
Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes	11
Induced pluripotent stem cell-derived mesenchymal stem cells for modeling and treating metabolic associated fatty liver disease and metabolic associated steatohepatitis: Challenges and opportunities	11
Inhibition of glutathione metabolism can limit the development of pancreatic cancer	11
Recent progress in hair follicle stem cell markers and their regulatory roles	11
Additional comments on extracellular vesicles derived from mesenchymal stem cells mediate extracellular matrix remodeling in osteoarthritis	11
Barriers to mesenchymal stromal cells for low back pain	11
Advancing human adipose-derived mesenchymal stem cell-derived exosomes for androgenetic alopecia: Appraisal and methodological recommendations	11
Refining adipose-derived stem cell isolation for optimal regenerative therapy	11
Expression of cancer stem cell markers and their prognostic significance in stage IIIA non-small cell lung cancer	10
Preliminary study on the preparation of lyophilized acellular nerve scaffold complexes from rabbit sciatic nerves with human umbilical cord mesenchymal stem cells	10
Crosstalk between Wnt and bone morphogenetic protein signaling during osteogenic differentiation	10
Adipose tissue as a living drug: Stromal vascular fraction and adipose tissue-derived stem cells in regenerative medicine	10
Bone marrow mesenchymal stem cell treatment improves post-stroke cerebral function recovery by regulating gut microbiota in rats	10
Gossypol acetic acid regulates leukemia stem cells by degrading LRPPRC via inhibiting IL-6/JAK1/STAT3 signaling or resulting mitochondrial dysfunction	10
Molecular mechanism of therapeutic approaches for human gastric cancer stem cells	10
Advances of nanotechnology applied to cancer stem cells	10
Safety and efficiency of Wharton’s Jelly-derived mesenchymal stem cell administration in patients with traumatic brain injury: First results of a phase I study	10
Exploring the critical therapeutic window: Dose-frequency optimization of human umbilical cord mesenchymal stem cells for preclinical asthma treatment	10
Living bio-drug therapies using mesenchymal stem cells and exosomes for mechanically ventilated patients with acute respiratory distress syndrome: A systematic review and meta-analysis	10
Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis	10
Anti-fibrotic effect of adipose-derived stem cells on fibrotic scars	10
Immortalization of epidural fat-derived mesenchymal stem cells: In vitro characterization and adipocyte differentiation potential	10
Adipokines regulate mesenchymal stem cell osteogenic differentiation	10
Combined mesenchymal and neural stem cell therapy enhances neurological recovery in cerebral infarction	9

Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease	9
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells	9
Circular RNAs inducing the osteogenic differentiation of dental mesenchymal stem cells via microRNA sponging	9
Innovative mesenchymal stem cell treatments for fatty liver disease	9
High glucose microenvironment and human mesenchymal stem cell behavior	9
Synergism of calycosin and bone marrow-derived mesenchymal stem cells to combat podocyte apoptosis to alleviate adriamycin-induced focal segmental glomerulosclerosis	9
Applications of artificial intelligence in stem cell therapy	9
Correction to “ADSC-Exos outperform BMSC-Exos in alleviating hydrostatic pressure-induced injury to retinal ganglion cells by upregulating nerve growth factors”	9
Stem cell transplantation in cerebrovascular accidents: A global bibliometric analysis (2000-2023)	8
Preliminary evidence of renal function improvement in chronic progressive kidney disease using autologous CD34+ cell therapy: A clinical trial	8
Stem cell therapy: A promising therapeutic approach for skeletal muscle atrophy	8
Stimulating factors for regulation of osteogenic and chondrogenic differentiation of mesenchymal stem cells	8
Human dental pulp stem/stromal cells in clinical practice	8
Breast cancer stem cells and circulating tumor cells: Dual drivers of progression and relapse	8
MiR-126 regulates the effect of mesenchymal stem cell vascular repair on carotid atherosclerosis through MAPK/ERK signaling pathway	8
How to enhance the ability of mesenchymal stem cells to alleviate intervertebral disc degeneration	8
Downregulation of miRNA-21 and cancer stem cells after chemotherapy results in better outcome in breast cancer patients	8
Melanoma cell adhesion molecule-positive mesenchymal stromal cells alleviate acute respiratory distress syndrome via nuclear factor kappa-B-mediated para	8
Optimizing mesenchymal stem cell therapy for tendon-bone healing: Multifaceted approaches and future directions	8
Engineering ligament tissues: Synergistic power of aligned nanofibers and cyclic stretch	8
Therapeutic applications of adipose-derived stromal vascular fractions in osteoarthritis	8
Potential plausible role of Wharton’s jelly mesenchymal stem cells for diabetic bone regeneration	8
Hypoxic preconditioned mesenchymal stem cell-derived exosomes alleviate oxidative stress-induced cardiomyocyte apoptosis through miR-486-5p	8
Human umbilical cord mesenchymal stromal cell-derived extracellular vesicles alleviate radiation induced pulmonary fibrosis	8
Application of mesenchymal stem cell therapy for premature ovarian insufficiency: Recent advances from mechanisms to therapeutics	7
WDR36 inhibits the osteogenic differentiation and migration of periodontal ligament stem cells	7
Constitutive aryl hydrocarbon receptor facilitates the regenerative potential of mouse bone marrow mesenchymal stromal cells	7
Umbilical cord mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy	7
Mesenchymal stem cell-derived exosomes and the Wnt/β-catenin pathway: Unifying mechanisms of multi-organ regeneration and the path to precision clinical translation	7
Silent saboteurs: How microplastics disrupt stem cells and tissue regeneration	7
Self-assembly of differentiated dental pulp stem cells facilitates spheroid human dental organoid formation and prevascularization	7
Effects of macrophages on the osteogenic differentiation of adipose tissue-derived stem cells in two-dimensional and three-dimensional cocultures	7
Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells	7
Role of brahma-related gene 1/brahma-associated factor subunits in neural stem/progenitor cells and related neural developmental disorders	7
Stromal vascular fraction: Mechanisms and application in reproductive disorders	7
Skinny people serum factors promote the differentiation of multipotent stem cells into brown adipose tissue	7
Efficacy and safety of umbilical cord-derived mesenchymal stem cell-conditioned media for preventing and treating skin aging	7
Dissecting molecular mechanisms underlying ferroptosis in human umbilical cord mesenchymal stem cells: Role of cystathionine γ-lyase/hydrogen sulfide pathway	7
Advances in human umbilical cord mesenchymal stem cells-derived extracellular vesicles and biomaterial assemblies for endometrial injury treatment	7
Molecular signaling in cancer stem cells of tongue squamous cell carcinoma: Therapeutic implications and challenges	6
Cyclodextrin host-guest complex to facilitate sinomenine-based osteoporosis therapy	6
Long non-coding RNA SNHG16 promotes human placenta-derived mesenchymal stem cell proliferation capacity through the PI3K/AKT pathway under hypoxia	6
Long noncoding ribonucleic acid ENST00000517482 enhances mesenchymal stem cell therapy against acute lung injury	6
Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors	6
Transcription regulators differentiate mesenchymal stem cells into chondroprogenitors, and their in vivo implantation regenerated the intervertebral disc degeneration	6
Long noncoding RNAs in mesenchymal stromal/stem cells osteogenic differentiation: Implications in osteoarthritis pathogenesis	6
Mesenchymal stem-derived exosomes enhance therapeutic benefits of exercise in isoproterenol-induced myocardial ischemia: Targeting ERK and Akt/mTOR signaling	6
Bibliometrics of trends in global research on the roles of stem cells in myocardial fibrosis therapy	6
Generation of a human haploid neural stem cell line for genome-wide genetic screening	6
Optimization of adipose tissue-derived mesenchymal stromal cells transplantation for bone marrow repopulation following irradiation	6
Application of extracellular vesicles from mesenchymal stem cells promotes hair growth by regulating human dermal cells and follicles	5
Childhood insulin resistance and neural stem cell dysfunction in psychiatric disorders: Role of de novo lipogenesis and treatment perspectives	5
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway	5
Reveal more mechanisms of precondition mesenchymal stem cells inhibiting inflammation	5
Mechanism of adipose-derived mesenchymal stem cell exosomes in the treatment of heart failure	5
Emergence of the stromal vascular fraction and secretome in regenerative medicine	5
Unravelling the reversion mechanisms of activated hepatic stellate cell properties by extracellular vesicles from mesenchymal stem cells	5
Human umbilical cord mesenchymal stem cells ameliorate liver metabolism in diabetic rats with metabolic-associated fatty liver disease	5
HIF-1α modulates β-catenin pathway to enhance the survival and angiogenesis of PBMSCs under hypoxia environment	5
Human amniotic fluid stem cell therapy can help regain bladder function in type 2 diabetic rats	5
Exosomes from circ-Astn1-modified adipose-derived mesenchymal stem cells enhance wound healing through miR-138-5p/SIRT1/FOXO1 axis regulation	5
Application of stem cell-derived exosomes in bone and joint diseases: Recent advances enabled by diverse carrier technologies	5
First-ever stem cell therapy restores insulin independence in type 1 diabetes: A medical milestone	5
Exosomes derived from microRNA-540-3p overexpressing mesenchymal stem cells promote immune tolerance via the CD74/nuclear factor-kappaB pathway in cardiac allograft	4
VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling	4
Obesity and cancer stem cells: Roles in cancer initiation, progression and therapy resistance	4
L-arginine: A promising metabolite in enhancing the protective effects of adipose-derived stem cells against ischemic pathologies	4
Mesenchymal stem cells-extracellular vesicles alleviate pulmonary fibrosis by regulating immunomodulators	4
Hypoxia and inflammatory factor preconditioning enhances the immunosuppressive properties of human umbilical cord mesenchymal stem cells	4
Sinomenine increases osteogenesis in mice with ovariectomy-induced bone loss by modulating autophagy	4
X inactive-specific transcript regulates mitochondrial function and neuronal differentiation of stem cells via IGF2BP2/CPT1A axis in models of spinal cord injury	4
When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients	4
Stem cell therapy applied for digestive anastomosis: Current state and future perspectives	4
Transplantation of human induced pluripotent stem cell derived keratinocytes accelerates deep second-degree burn wound healing	4
Clinical application prospects and transformation value of dental follicle stem cells in oral and neurological diseases	4
Human umbilical cord mesenchymal stem cells reduce platelet α-granule release in rats via the AKT/MEK/ERK pathway during acute exposure to high-altitude hypoxia	4
Does standalone/combined subchondral bone marrow-derived mesenchymal stem/stromal cell injection offer significantly better clinical benefit to intraarticular injection in knee osteoarthritis?	4
Integrin beta 3-overexpressing mesenchymal stromal cells display enhanced homing and can reduce atherosclerotic plaque	3
Molecular and therapeutic effects of mesenchymal stem cell-derived exosomes on autoimmune diseases	3
Extracellular vesicles from adipose-derived stem cells in bone regeneration: Mechanisms and therapeutic advances	3

Immunomodulation: The next target of mesenchymal stem cell-derived exosomes in the context of ischemic stroke	3
Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice	3
Multiple roles of mothers against decapentaplegic homolog 4 in tumorigenesis, stem cells, drug resistance, and cancer therapy	3
Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells	3
Mesenchymal stem cells-derived exosomes alleviate radiation induced pulmonary fibrosis by inhibiting the protein kinase B/nuclear factor kappa B pathway	3
L-arginine from elder human mesenchymal stem cells induces angiogenesis and enhances therapeutic effects on ischemic heart diseases	3
Mid-term outcomes of microfragmented adipose tissue plus arthroscopic surgery for knee osteoarthritis: A randomized, active-control, multicenter clinical trial	3
Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing via creating a fetal-like niche	3
Stem cell therapy for insulin-dependent diabetes: Are we still on the road?	3
Unveiling the role of hypoxia-inducible factor 2alpha in osteoporosis: Implications for bone health	3
Optimal good manufacturing practice-compliant production of dental follicle stem cell sheet and its application in Sprague-Dawley rat periodontitis	3
Culture and identification of neonatal rat brain-derived neural stem cells	3
Resilience and challenges: Evaluating the impact of stress conditions on mesenchymal stem cells across different passages	3
Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives	3
Dual role of extracellular vesicles in neurodegenerative diseases	3
Use of priming strategies to advance the clinical application of mesenchymal stromal/stem cell-based therapy	3
Human umbilical cord mesenchymal stem cell-derived exosomal miR-199a-3p inhibits the MAPK4/NF-κB signaling pathway to relieve osteoarthritis	3
Pretreatment can alleviate programmed cell death in mesenchymal stem cells	3
Melatonin regulation and the function of the periodontal ligament: Future perspective and challenges	2
Engineering the future of nanomedicine: Strategic approaches to extracellular vesicle-based drug administration regimens	2
Therapeutic strategies for intervertebral disc degeneration: Extracellular vesicles and microRNAs derived from mesenchymal stem cells	2
Thymoquinone inhibited the chondrogenic differentiation of tendon-derived stem cells caused by tendon injury	2
Role of stem cells-based in facial nerve reanimation: A meta-analysis of histological and neurophysiological outcomes	2
Perspectives on Schwann-like cells derived from bone marrow-mesenchymal stem cells: Advancing peripheral nerve injury therapies	2
Effect of tandem autologous stem cell transplantation on survival in pediatric patients with high-risk solid tumors in South China	2
Calcifying nanoparticles induce apoptosis and calcification in bone marrow mesenchymal stem cells via the transforming growth factor-β/Smad pathway	2
Adipose-derived regenerative therapies for the treatment of knee osteoarthritis	2
Effects of interleukin-10 treated macrophages on bone marrow mesenchymal stem cells via signal transducer and activator of transcription 3 pathway	2
Zinc enhances the cell adhesion, migration, and self-renewal potential of human umbilical cord derived mesenchymal stem cells	2
Therapeutic potential of stem cell-derived exosomes in hair regeneration: A systematic review	2
Wumei Pills enhance intestinal stem cell - mediated repair in chemotherapy-induced mucositis via Lactobacillus reuteri - dependent modulation of the gut microbiota	2
Outcomes of combined mitochondria and mesenchymal stem cells-derived exosome therapy in rat acute respiratory distress syndrome and sepsis	2
Advances in mesenchymal stem cell therapy for lupus nephritis	2
Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome	2
Melatonin-based priming of stem cells to alleviate oxidative stress	2
Human pluripotent stem cell-derived kidney organoids: Current progress and challenges	2
Challenges in the clinical translation of stromal vascular fraction therapy in regenerative medicine	2
Exosomal miR-203 from bone marrow stem cells targets the SOCS3/NF-κB pathway to regulate neuroinflammation in temporal lobe epilepsy	2
Non-coding RNAs in adipose-derived stem cell exosomes: Mechanisms, therapeutic potential, and challenges in wound healing	2
Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages	2
GATA binding protein 2 mediated ankyrin repeat domain containing 26 high expression in myeloid-derived cell lines	2
Potential regulatory effects of stem cell exosomes on inflammatory response in ischemic stroke treatment	2
Entering the era of living biopharmaceuticals for treating knee osteoarthritis: A systematic review and network meta-analysis	2
Adult neural stem cells and schizophrenia	2
Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment	2
Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology	2
Interplay between mesenchymal stem cells and macrophages: Promoting bone tissue repair	2
Quercetin pretreated umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease via IL-10 /Janus kinase 2/STAT3 signaling	2
Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression	2
Dual role and clinical application of extracellular vesicles in acute respiratory distress syndrome: Mechanism analysis and translational challenges	2
Microvesicles derived from mesenchymal stem cells inhibit acute respiratory distress syndrome-related pulmonary fibrosis in mouse partly through hepatocyte growth factor	2
How the interplay among the tumor microenvironment and the gut microbiota influences the stemness of colorectal cancer cells	2
Cardiac stem cells: Current knowledge and future prospects	2