World Journal of Gastrointestinal Oncology

Article	Citations
Young-onset colorectal cancer: A review	47
Early-onset colorectal cancer: Current insights and future directions	36
Liquid biopsy in cholangiocarcinoma: Current status and future perspectives	34
Colorectal cancer screening in the COVID-19 era	31
Neoadjuvant chemotherapy for colorectal liver metastases: A contemporary review of the literature	27
Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis	26
Synergistic anti-liver cancer effects of curcumin and total ginsenosides	25
Nanotechnology and pancreatic cancer management: State of the art and further perspectives	24
Colorectal cancer carcinogenesis: From bench to bedside	22
Radiomics in hepatocellular carcinoma: A state-of-the-art review	21
Diverse roles of FOXO family members in gastric cancer	21
Microbiome and colorectal carcinogenesis: Linked mechanisms and racial differences	21
Small bowel adenocarcinoma: An overview	21
Achievement of complete response to nivolumab in a patient with advanced sarcomatoid hepatocellular carcinoma: A case report	20
Diagnostic value of four serum exosome microRNAs panel for the detection of colorectal cancer	20
Helicobacter pylori infection and other bacteria in pancreatic cancer and autoimmune pancreatitis	20
Inflammatory bowel disease-related colorectal cancer: Past, present and future perspectives	20
Helicobacter pylori, gastric microbiota and gastric cancer relationship: Unrolling the tangle	20
Unique situation of hepatocellular carcinoma in Egypt: A review of epidemiology and control measures	19
BRAFV600E mutant colorectal cancer cells mediate local immunosuppressive microenvironment through exosomal long noncoding RNAs	19
Claudin 18.2 is a potential therapeutic target for zolbetuximab in pancreatic ductal adenocarcinoma	19
Regulatory RNAs, microRNA, long-non coding RNA and circular RNA roles in colorectal cancer stem cells	19
Endoscopic or percutaneous biliary drainage in hilar cholangiocarcinoma: When and how?	18
Overgrowth of Lactobacillus in gastric cancer	18
Prognostic significance of KIF23 expression in gastric cancer	18

Recent advances in targeted therapy for pancreatic adenocarcinoma	17
Gastric epithelial histology and precancerous conditions	17
Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside	17
Nutritional therapy for hepatocellular carcinoma	17
Scoparone inhibits pancreatic cancer through PI3K/Akt signaling pathway	17
Development of artificial intelligence technology in diagnosis, treatment, and prognosis of colorectal cancer	17
Gallbladder cancer: Historical treatment and new management options	17
Colorectal cancer in Arab world: A systematic review	17
Efficacy and safety of anti-PD-1/anti-PD-L1 antibody therapy in treatment of advanced gastric cancer or gastroesophageal junction cancer: A meta-analysis	16
Digestive cancer incidence and mortality among young adults worldwide in 2020: A population-based study	15
Minimally invasive surgical treatment of intrahepatic cholangiocarcinoma: A systematic review	15
Immunotherapy in liver transplantation for hepatocellular carcinoma: Pros and cons	14
Review of incidence and outcomes of treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis	14
Pancreatic intraductal papillary mucinous neoplasms: Current diagnosis and management	14
Programmed death 1, ligand 1 and 2 correlated genes and their association with mutation, immune infiltration and clinical outcomes of hepatocellular carcinoma	14
Myeloid-derived suppressor cells in gastrointestinal cancers: A systemic review	14
Oncological outcomes and predictors of radiofrequency ablation of colorectal cancer liver metastases	14
Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease	13
Decreased expression of the long non-coding RNA HOXD-AS2 promotes gastric cancer progression by targeting HOXD8 and activating PI3K/Akt signaling pathway	13
Highly accurate colorectal cancer prediction model based on Raman spectroscopy using patient serum	13
Clinicopathological characteristics and prognosis of 77 cases with type 3 gastric neuroendocrine tumours	13
Pathological, molecular, and clinical characteristics of cholangiocarcinoma: A comprehensive review	13
Current role of hepatopancreatoduodenectomy for the management of gallbladder cancer and extrahepatic cholangiocarcinoma: A systematic review	13
Biomarkers for hepatocellular carcinoma based on body fluids and feces	13
Management of obstructive colon cancer: Current status, obstacles, and future directions	12
Neoantigen vaccine: An emerging immunotherapy for hepatocellular carcinoma	12
Diagnostic performance of narrow-band imaging international colorectal endoscopic and Japanese narrow-band imaging expert team classification systems for colorectal cancer and precancerous lesions	12
Advances in postoperative adjuvant therapy for primary liver cancer	12
Poorly cohesive cells gastric carcinoma including signet-ring cell cancer: Updated review of definition, classification and therapeutic management	12
Management of single pulmonary metastases from colorectal cancer: State of the art	12
Multimodal treatment in oligometastatic gastric cancer	12
Application of the woodchuck animal model for the treatment of hepatitis B virus-induced liver cancer	12
Notch signalling pathway in development of cholangiocarcinoma	12
Recent update on comprehensive therapy for advanced hepatocellular carcinoma	12
Gastric cancer: An epigenetic view	12
Atezolizumab plus bevacizumab versus sorafenib or atezolizumab alone for unresectable hepatocellular carcinoma: A systematic review	11
Total neoadjuvant therapy vs standard therapy of locally advanced rectal cancer with high-risk factors for failure	11
Bromodomain and extra-terminal inhibitors emerge as potential therapeutic avenues for gastrointestinal cancers	11
Role of exosomal long non-coding RNAs in colorectal cancer	11
Lateral pelvic lymph nodes for rectal cancer: A review of diagnosis and management	11
Molecular regulatory mechanism of ferroptosis and its role in gastrointestinal oncology: Progress and updates	11
Identification of a nine-gene prognostic signature for gastric carcinoma using integrated bioinformatics analyses	11
LncRNA C9orf139 can regulate the growth of pancreatic cancer by mediating the miR-663a/Sox12 axis	11
Crosstalk between gut microbiota and COVID-19 impacts pancreatic cancer progression	11
Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics	11
Non-surgical treatment of hilar cholangiocarcinoma	11
Neutrophile-to-lymphocyte, lymphocyte-to-monocyte, and platelet-to-lymphocyte ratios as prognostic and response biomarkers for resectable locally advanced gastric cancer	11
Mesenchymal stem cell-derived exosomes for gastrointestinal cancer	11
Molecular determinants of response to 5-fluorouracil-based chemotherapy in colorectal cancer: The undisputable role of micro-ribonucleic acids	11
Prognostic impact of at least 12 lymph nodes after neoadjuvant therapy in rectal cancer: A meta-analysis	11

Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways	11
Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model	10
Neutrophil-to-lymphocyte ratio and carbohydrate antigen 19-9 as prognostic markers for advanced pancreatic cancer patients receiving first-line chemotherapy	10
Outcomes of curative esophageal cancer surgery in elderly: A meta-analysis	10
Anatomical vs nonanatomical liver resection for solitary hepatocellular carcinoma: A systematic review and meta-analysis	10
Extracellular vesicles: General features and usefulness in diagnosis and therapeutic management of colorectal cancer	10
Prognostic significance of Borrmann type combined with vessel invasion status in advanced gastric cancer	10
Immune evasion mechanisms and therapeutic strategies in gastric cancer	10
Thermal ablation and immunotherapy for hepatocellular carcinoma: Recent advances and future directions	10
Primary malignant vascular tumors of the liver in children: Angiosarcoma and epithelioid hemangioendothelioma	10
Association between intestinal neoplasms and celiac disease: A review	10
Influence of primary tumor location and resection on survival in metastatic colorectal cancer	10
Molecular testing for colorectal cancer: Clinical applications	10
Exosomes as potential diagnosis and treatment for liver cancer	10
Novel perspective in pancreatic cancer therapy: Targeting ferroptosis pathway	10
Endoscopic ultrasound assessment and tissue acquisition of mediastinal and abdominal lymph nodes	9
Is the combination of immunotherapy with conventional chemotherapy the key to increase the efficacy of colorectal cancer treatment?	9
Clinical characteristics and outcome of primary hepatic neuroendocrine tumors after comprehensive therapy	9
Sporadic fundic gland polyps with dysplasia or carcinoma: Clinical and endoscopic characteristics	9
Fibrolamellar hepatocellular carcinoma: A rare but unpleasant event	9
Update on the management of the gastrointestinal effects of radiation	9
Role of autophagy in cholangiocarcinoma: An autophagy-based treatment strategy	9
Effects ofHelicobacter pyloriinfection in gastrointestinal tract malignant diseases: From the oral cavity to rectum	9
Glutamine deprivation impairs function of infiltrating CD8+ T cells in hepatocellular carcinoma by inducing mitochondrial damage and apoptosis	9
Characterization of metabolic landscape in hepatocellular carcinoma	9
Current controversies and advances in the management of pancreatic adenocarcinoma	9
Incidence and prevalence of gastric neuroendocrine tumors in patients with chronic atrophic autoimmune gastritis	9
VCAN, expressed highly in hepatitis B virus-induced hepatocellular carcinoma, is a potential biomarker for immune checkpoint inhibitors	9
Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions	8
Engineering nanotheranostic strategies for liver cancer	8
Endoscopic ultrasound-guided ablation of solid pancreatic lesions: A systematic review of early outcomes with pooled analysis	8
Prognostic value of claudin 18.2 expression in gastric adenocarcinoma	8
Macrophages play a role in inflammatory transformation of colorectal cancer	8
Familial adenomatous polyposis and changes in the gut microbiota: New insights into colorectal cancer carcinogenesis	8
Role of three-dimensional printing and artificial intelligence in the management of hepatocellular carcinoma: Challenges and opportunities	8
Traditional Chinese medicine for transformation of gastric precancerous lesions to gastric cancer: A critical review	8
Plexiform fibromyxoma: Review of rare mesenchymal gastric neoplasm and its differential diagnosis	8
Relation between skeletal muscle volume and prognosis in rectal cancer patients undergoing neoadjuvant therapy	8
Liquid biopsy approach to pancreatic cancer	8
Intratumour microbiome of pancreatic cancer	8
Current status of non-surgical treatment of locally advanced pancreatic cancer	8
Methylation changes at the GNAS imprinted locus in pancreatic cystic neoplasms are important for the diagnosis of malignant cysts	8
Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers	8
MicroRNA expression in inflammatory bowel disease-associated colorectal cancer	8
Blood exosomal micro ribonucleic acid profiling reveals the complexity of hepatocellular carcinoma and identifies potential biomarkers for differential diagnosis	8
Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer	8
What is the best surgical procedure of transverse colon cancer? An evidence map and minireview	8
Endoscopic radiofrequency ablation for malignant biliary obstruction	8
How the COVID-19 pandemic has affected the colorectal cancer screening in Italy: A minireview	7
Cuproptosis-related long non-coding RNAs model that effectively predicts prognosis in hepatocellular carcinoma	7
Can dietary flavonoids be useful in the personalized treatment of colorectal cancer?	7
Low body mass index is an independent predictor of poor long-term prognosis among patients with resectable gastric cancer	7
Role of neoadjuvant therapy for nonmetastatic pancreatic cancer: Current evidence and future perspectives	7
Comparison of prognostic factors in different age groups and prognostic significance of neutrophil-lymphocyte ratio in patients with gastric cancer	7
Clinical significance of molecular subtypes of gastrointestinal tract adenocarcinoma	7
Comparison of tumor regression grading systems for locally advanced gastric adenocarcinoma after neoadjuvant chemotherapy	7
Solid extraintestinal malignancies in patients with inflammatory bowel disease	7
Vasoactive intestinal peptide secreting tumour: An overview	7
Challenges and exploration for immunotherapies targeting cold colorectal cancer	7
Sarcopenia in pancreatic cancer: Effect on patient outcomes	7
Scoping out the future: The application of artificial intelligence to gastrointestinal endoscopy	7
Robotic resection of liver focal nodal hyperplasia guided by indocyanine green fluorescence imaging: A preliminary analysis of 23 cases	7
Characterizing the patient experience during neoadjuvant therapy for pancreatic ductal adenocarcinoma: A qualitative study	7
Practical considerations for colorectal cancer screening in older adults	7
Research progress of integrated traditional Chinese and Western medicine in the treatment of advanced gastric cancer	7
Laparoscopic liver resection for colorectal liver metastases — short- and long-term outcomes: A systematic review	7
Pancreatic head vs pancreatic body/tail cancer: Are they different?	7
Sex as an effect modifier in the association between alcohol intake and gastric cancer risk	7
Proteasome regulators in pancreatic cancer	6
Proliferating cell nuclear antigen clamp associated factor, a potential proto-oncogene with increased expression in malignant gastrointestinal tumors	6
Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers	6
Comprehensive molecular characterization and identification of prognostic signature in stomach adenocarcinoma on the basis of energy-metabolism-related genes	6
Molecular-targeted therapy toward precision medicine for gastrointestinal caner: Current progress and challenges	6
Potential utility of liquid biopsies in the management of patients with biliary tract cancers: A review	6
Comparison of survival between adolescent and young adult vs older patients with hepatocellular carcinoma	6
Second-line therapy for advanced hepatocellular carcinoma with regorafenib or cabozantinib: Multicenter French clinical experience in real-life after matching	6
Should we resect colorectal cancer in patients over the age of 85?	6
Screening strategy for gastrointestinal and hepatopancreatobiliary cancers in cystic fibrosis	6
Survival effect of probiotics in a rat model of colorectal cancer treated with capecitabine	6
Berberine retarded the growth of gastric cancer xenograft tumors by targeting hepatocyte nuclear factor 4α	6

Predictors for malignant potential and deep submucosal invasion in colorectal laterally spreading tumors	6
Latest therapeutic target for gastric cancer: Anthrax toxin receptor 1	6
Trimodality treatment in gastric and gastroesophageal junction cancers: Current approach and future perspectives	6
Changing trends of clinicopathologic features and survival duration after surgery for gastric cancer in Northeast China	6
Clinical implications of interleukins-31, 32, and 33 in gastric cancer	6
High expression of protein phosphatase 2 regulatory subunit B'' alpha predicts poor outcome in hepatocellular carcinoma patients after liver transplantation	6
Radiofrequency ablation in the management of primary hepatic and biliary tumors	6
Portal vein embolization failure: Current strategies and future perspectives to improve liver hypertrophy before major oncological liver resection	6
Angiotensin-converting enzyme 2 connects COVID-19 with cancer and cancer immunotherapy	6
Molecular methods for colorectal cancer screening: Progress with next-generation sequencing evolution	6
Serum vascular endothelial growth factor as a tumor marker for hepatocellular carcinoma in hepatitis C virus-related cirrhotic patients	6
Clinical management for malignant afferent loop obstruction	6
Preventive and inhibitive effects of Yiwei Xiaoyu granules on the development and progression of spasmolytic polypeptide-expressing metaplasia lesions	6
Immunotherapy for nonalcoholic fatty liver disease-related hepatocellular carcinoma: Lights and shadows	6
Same day yttrium-90 radioembolization with single photon emission computed tomography/computed tomography: An opportunity to improve care during the COVID-19 pandemic and beyond	6
Stereotactic radiotherapy for intrahepatic cholangiocarcinoma	6
Outcomes of curative liver resection for hepatocellular carcinoma in patients with cirrhosis	6
Effects of dietary zinc deficiency on esophageal squamous cell proliferation and the mechanisms involved	6
Angiogenesis in gastrointestinal stromal tumors: From bench to bedside	6
Role of mammalian target of rapamycin complex 2 in primary and secondary liver cancer	6
Effect of oncometabolic surgery on gastric cancer: The remission of hypertension, type 2 diabetes mellitus, and beyond	6
Increased CD4/CD8 Lymphocyte ratio predicts favourable neoadjuvant treatment response in gastric cancer: A prospective pilot study	6
Clinical efficacy and prognostic risk factors of endoscopic radiofrequency ablation for gastric low-grade intraepithelial neoplasia	6
Clinicopathological differences, risk factors and prognostic scores for western patients with intestinal and diffuse-type gastric cancer	6
Cutaneous metastases of pancreatic carcinoma to the labia majora: A case report and review of literature	5
RNA-Seq profiling of circular RNAs in human colorectal cancer 5-fluorouracil resistance and potential biomarkers	5
Clinical implications and perspectives of portal venous circulating tumor cells in pancreatic cancer	5
Gut microbiota and immune system in liver cancer: Promising therapeutic implication from development to treatment	5
Rare common bile duct metastasis of breast cancer: A case report and literature review	5
Regorafenib combined with programmed cell death-1 inhibitor against refractory colorectal cancer and the platelet-to-lymphocyte ratio’s prediction on effectiveness	5
Interleukin-34 promotes the proliferation and epithelial-mesenchymal transition of gastric cancer cells	5
Effect of obesity on post-operative outcomes following colorectal cancer surgery	5
Lipid metabolism of hepatocellular carcinoma impacts targeted therapy and immunotherapy	5
Circular RNAs in hepatocellular carcinoma: Recent advances	5
New frontiers in liver ultrasound: From mono to multi parametricity	5
Application of metabolomics in clinical and laboratory gastrointestinal oncology	5
Combined treatments in hepatocellular carcinoma: Time to put them in the guidelines?	5
Cost-effective low-coverage whole-genome sequencing assay for the risk stratification of gastric cancer	5
Role of autophagy in gastric carcinogenesis	5
Role of ferroptosis in colorectal cancer	5
Yield of surgery in solid pseudopapillary neoplasms of the pancreas: A case series and literature review	5
Current guidelines in the surgical management of hereditary colorectal cancers	5
Esophageal cancer screening, early detection and treatment: Current insights and future directions	5
Computed tomography-based radiomic to predict resectability in locally advanced pancreatic cancer treated with chemotherapy and radiotherapy	5
Minimally invasive vs open pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors	5
Shuyu pills inhibit immune escape and enhance chemosensitization in hepatocellular carcinoma	5
Role of endoscopic ultrasound in anticancer therapy: Current evidence and future perspectives	5
Contemporary treatment approaches for metastatic colorectal cancer driven by BRAF V600 mutations	5
Endoscopic papillectomy for ampullary adenomatous lesions: A literature review	5
Oxidative imbalance increases the risk for colonic polyp and colorectal cancer development	5
“Cold” colorectal cancer faces a bottleneck in immunotherapy	5
Fecal microbial biomarkers combined with multi-target stool DNA test improve diagnostic accuracy for colorectal cancer	5
Risk factors, prognostic predictors, and nomograms for pancreatic cancer patients with initially diagnosed synchronous liver metastasis	5
Neoadjuvant therapy in resectable pancreatic cancer: A promising curative method to improve prognosis	5
Baseline neutrophil-lymphocyte ratio and platelet-lymphocyte ratio appear predictive of immune treatment related toxicity in hepatocellular carcinoma	5
B7 homologue 3 as a prognostic biomarker and potential therapeutic target in gastrointestinal tumors	5
Genome-wide CRISPR-Cas9 screening identifies that hypoxia-inducible factor-1a-induced CBX8 transcription promotes pancreatic cancer progression via IRS1/AKT axis	5
Moving forward in the treatment of cholangiocarcinoma	4
O6-methylguanine DNA methyltransferase is upregulated in malignant transformation of gastric epithelial cells via its gene promoter DNA hypomethylation	4
Deep learning-based radiomics based on contrast-enhanced ultrasound predicts early recurrence and survival outcome in hepatocellular carcinoma	4
Influence of the heat irrigating effect of radiofrequency ablation on regional liver tissue in Bama miniature pigs	4
Efficacy of neoadjuvant chemotherapy for initially resectable colorectal liver metastases: A retrospective cohort study	4
Conservative management of malignant gastric outlet obstruction syndrome-evidence based evaluation of endoscopic ultrasound-guided gastroentero-anastomosis	4
Prognostic value of modified Lauren classification in gastric cancer	4
Role of tumor-associated macrophages in common digestive system malignant tumors	4
Potential of six-transmembrane epithelial antigen of the prostate 4 as a prognostic marker for colorectal cancer	4
Internal hemorrhoid harboring adenocarcinoma: A case report	4
Statin as a therapeutic agent in gastroenterological cancer	4
Survival outcomes and prognostic indicators for gastric cancer patients with positive peritoneal wash cytology but no peritoneal metastasis after radical gastrectomy	4
Crohn’s disease with infliximab treatment complicated by rapidly progressing colorectal cancer: A case report	4
Neoadjuvant chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis	4
Proteomic signatures of infiltrative gastric cancer by proteomic and bioinformatic analysis	4
Does the addition of Braun anastomosis to Billroth II reconstruction on laparoscopic-assisted distal gastrectomy benefit patients?	4
Correlation between immune-related adverse events and long-term outcomes in pembrolizumab-treated patients with unresectable hepatocellular carcinoma: A retrospective study	4
Comprehensive analysis of distal-less homeobox family gene expression in colon cancer	4
γ-glutamyl transferase-to-platelet ratio based nomogram predicting overall survival of gallbladder carcinoma	4
Nutrition deprivation affects the cytotoxic effect of CD8 T cells in hepatocellular carcinoma	4
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway	4
Overexpression of ELL-associated factor 2 suppresses invasion, migration, and angiogenesis in colorectal cancer	4
Exosomes in metastasis of colorectal cancers: Friends or foes?	4
EFNA1in gastrointestinal cancer: Expression, regulation and clinical significance	4
Real-time fluorescence image-guided gastrointestinal oncologic surgery: Towards a new era	4
Liver tumors in children with chronic liver diseases	4
Prognostic impact of tumor deposits on overall survival in colorectal cancer: Based on Surveillance, Epidemiology, and End Results database	4
MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling	4
Diffuse reduction of spleen density is a novel prognostic marker for intrahepatic cholangiocarcinoma after curative resection	4
KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling	4
Hemoglobin, albumin, lymphocyte, and platelet score as a predictor of prognosis in metastatic gastric cancer	4
Digital single-operator cholangioscopy for biliary stricture after cadaveric liver transplantation	4
Multinational survey on the preferred approach to management of Barrett’s esophagus in the Asia-Pacific region	4
Biofeedback therapy combined with Baduanjin on quality of life and gastrointestinal hormone level in patients with colorectal cancer	4
Diabetes mellitus contribution to the remodeling of the tumor microenvironment in gastric cancer	4
Prospect of lenvatinib for unresectable hepatocellular carcinoma in the new era of systemic chemotherapy	4
Progress in the treatment of advanced hepatocellular carcinoma with immune combination therapy	4
Regulatory role of the transforming growth factor-β signaling pathway in the drug resistance of gastrointestinal cancers	4