OOIR: Observatory of International Research

Papers

(The median citation count of ACS Chemical Neuroscience is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Issue Editorial Masthead	106
Issue Editorial Masthead	104
Issue Editorial Masthead	92
Issue Publication Information	87
Issue Publication Information	85
Synthesis and Neuroprotective Evaluation of Substituted Indanone/Benzofuranone and Piperidine Hybrids	82
Issue Publication Information	79
Neurochemical and Morphological Comparisons of Motor Nerve Organoids and Spinal-Cord Explants	73
Targeting Microglial Immunoproteasome: A Novel Approach in Neuroinflammatory-Related Disorders	68
FPT, a 2-Aminotetralin, Is a Potent Serotonin 5-HT_1A, 5-HT_1B, and 5-HT_1D Receptor Agonist That Modulates Cortical Electroencephalogram Activity in Adult Fmr1 Kn	64
Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors	59
Study on the Difference of Protective Efficacy and Mechanism of Radix Aconiti Coreani and Rhizoma Typhonii in Gerbils with Ischemic Stroke	56
Repurposing Anakinra for Alzheimer’s Disease: The In Vitro and In Vivo Effects of Anakinra on LPS- and AC-Induced Neuroinflammation	54
Rimota-Gd: Paramagnetic Probe for In Vivo MRI Studies of the Cannabinoid 1 Receptor Distribution in the Mouse Brain	52
Correction to “Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in Vitro and in Vivo”	52
Pathological Mutations D169G and P112H Electrostatically Aggravate the Amyloidogenicity of the Functional Domain of TDP-43	51
Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex	50
Synthesis and Evaluation of Benzylic ¹⁸F-Labeled N-Biphenylalkynyl Nipecotic Acid Derivatives for PET Imaging of GABA Transporter 1	46
Novel Imidazole Phenoxyacetic Acids as Inhibitors of USP30 for Neuroprotection Implication via the Ubiquitin-Rho-110 Fluorometric Assay: Design, Synthesis, and In Silico and Biochemical Assays	46
Repeated Endomorphin Analogue MEL-0614 Reduces Tolerance and Improves Chronic Postoperative Pain without Modulating the P2X7R Signaling Pathway	45
Competitive Antagonism of Xylazine on α7 Nicotinic Acetylcholine Receptors and Reversal by Curcuminoids	45
Enhanced Analgesic Efficacy and Reduced Side Effects of Morphine by Combination with PD-1 Agonist	45
Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D	44
Disease-Associated Mutations in Tau Encode for Changes in Aggregate Structure Conformation	42
Impaired Dopamine Release and Latent Learning in Alzheimer’s Disease Model Zebrafish	41

Caffeine and Nicotine with N-Substituted Diazirine Photoaffinity Labels Form Adducts at Tyrosine-39 of α-Synuclein	41
Unraveling the Interplay of Dopamine, Carbon Monoxide, and Heme Oxygenase in Neuromodulation and Cognition	40
Role of NLRP3 Inflammasome in Post-Spinal-Cord-Injury Anxiety and Depression: Molecular Mechanisms and Therapeutic Implications	39
Discrimination between Alpha-Synuclein Protein Variants with a Single Nanometer-Scale Pore	39
The Orphan Receptor GPR151: Discovery, Expression, and Emerging Biological Significance	39
All Hands on Deck: We Need Multiple Approaches To Uncover the Neuroscience behind the Opioid Overdose Crisis	37
Pharmacokinetic Approach to Combat the Synthetic Cannabinoid PB-22	37
JNK3 Overexpression in the Entorhinal Cortex Impacts on the Hippocampus and Induces Cognitive Deficiencies and Tau Misfolding	36
Role of Bmal1 and Gut Microbiota in Alzheimer’s Disease and Parkinson’s Disease Pathophysiology: The Probable Effect of Melatonin on Their Association	36
New Multitarget Molecules Derived from Caffeine as Potentiators of the Cholinergic System	35
miR-29a/b1 Regulates BACE1 in Aluminum-Induced Aβ Deposition in Vitro	35
Lateral Habenula and Its Potential Roles in Pain and Related Behaviors	34
Exploring the Application Potential of α-Synuclein Molecular Probes in Early Diagnosis of Parkinson’s Disease: Focus on Imaging Methods	34
GPR68 Improves Nerve Damage and Myelination in an Immature Rat Model Induced by Sevoflurane Anesthesia by Activating cAMP/CREB to Mediate BDNF	33
Dl-3-n-Butylphthalide Alleviates Cognitive Impairment in Chronic Cerebral Hypoperfusion: Associations with Mitochondrial Permeability Transition Pore Closure and Suppression of Excessive Mitoph	33
Optimized TrkB Agonist Ameliorates Alzheimer’s Disease Pathologies and Improves Cognitive Functions via Inhibiting Delta-Secretase	32
Microinvasive Probes for Monitoring Electrical and Chemical Neural Activity in Nonhuman Primates	32
Emerging Frontiers in Conformational Exploration of Disordered Proteins: Integrating Autoencoder and Molecular Simulations	32
Chrysin-Loaded Chitosan Nanoparticle-Mediated Neuroprotection in Aβ_1–42-Induced Neurodegenerative Conditions in Zebrafish	32
Ferroptosis, Pyroptosis, and Cuproptosis in Alzheimer’s Disease	32
Issue Publication Information	31
Rational Design, Synthesis, and Evaluation of Rofecoxib-Based Photosensitizers for the NIR Imaging and Photo-Oxidization of Aβ Aggregates	31
Baihe Extracts Reduce the Activation and Apoptosis of Microglia in the Hippocampus of Mice with Depression-like Behaviors by Downregulating MYC	31
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Restricts Inflammatory Progression through Limiting Macrophage Infiltration in DRG and Sciatic Nerve during Diabetic Peripheral Neuropathy	31
Issue Editorial Masthead	30
Issue Editorial Masthead	30
Synthesis, Pharmacological Characterization, and Binding Mode Analysis of 8-Hydroxy-Tetrahydroisoquinolines as 5-HT₇ Receptor Inverse Agonists	30
Issue Publication Information	30
Issue Editorial Masthead	30
Issue Editorial Masthead	30
Artificial Neural Networks Coupled with MALDI-TOF MS Serum Fingerprinting To Classify and Diagnose Pathological Pain Subtypes in Preclinical Models	29
Cytotoxicity of Amyloid β1–42 Fibrils to Brain Immune Cells	29
Rapid Generation of Neurospheres from Hippocampal Neurons Using Extracellular-Matrix-Mimetic Scaffolds	28
Transthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands	28
Aspartic Acid-Modified Phospholipids Regulate Cell Response and Rescue Memory Deficits in APP/PS1 Transgenic Mice	28
Taylor Dispersion Analysis and Atomic Force Microscopy Provide a Quantitative Insight into the Aggregation Kinetics of Aβ (1–40)/Aβ (1–42) Amyloid Peptide Mixtures	27
Preclinical Evaluation of [¹¹C]YC-72-AB85 for In Vivo Visualization of Heat Shock Protein 90 in Brain and Cancer with Positron Emission Tomography	27
Multifarious Targets and Recent Developments in the Therapeutics for the Management of Bone Cancer Pain	27
Citric Acid-Derived Carbon Quantum Dots Attenuate Paraquat-Induced Neuronal Compromise In Vitro and In Vivo	26
Reactivity of Olanzapine and Tricyclic Antidepressants on the Protective Effects of Trolox on Lipid Peroxidation Evaluated Using Fluorescence Anisotropy, Electron Paramagnetic Resonance Spectrometry,	26
3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain	26
Neuroprotective Effects of σ₂R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington’s Disease	26
Issue Editorial Masthead	26
α₁ Proline 277 Residues Regulate GABA_AR Gating through M2-M3 Loop Interaction in the Interface Region	25
Defects in Mouse Cortical Glutamate Uptake Can Be Unveiled In Vivo by a Two-in-One Quantitative Microdialysis	25
Hyperphosphorylation-Mimetic TDP-43 Drives Amyloid Formation and Possesses Neuronal Toxicity at the Oligomeric Stage	25
Damage of the Phospholipid Bilayer by Aβ42 at Physiologically Relevant Peptide Concentrations	25
Role of Necroptosis in Central Nervous System Diseases	24
5-HT₃ Receptor MX Helix Contributes to Receptor Function	24
Neuroprotective Effects of an N-Salicyloyl Tryptamine Derivative against Cerebral Ischemia/Reperfusion Injury	24

Subchronic Acrylamide Exposure Activates PERK-eIF2α Signaling Pathway and Induces Synaptic Impairment in Rat Hippocampus	24
The Mineralocorticoid Receptor: An Emerging Pharmacotherapeutic Target for Alcohol Use Disorder?	24
Methylmalonic Acid Compromises Respiration and Reduces the Expression of Differentiation Markers of SH-SY5Y Human Neuroblastoma Cells	24
TRIOL Inhibits Rapid Intracellular Acidification and Cerebral Ischemic Injury: The Role of Glutamate in Neuronal Metabolic Reprogramming	23
Sequence-Dependent Conformational Properties of PGGG Motif in Tau Repeats: Insights from Molecular Dynamics Simulations of Narrow Pick Filament	23
Novel Small-Molecule Inhibitor of NLRP3 Inflammasome Reverses Cognitive Impairment in an Alzheimer’s Disease Model	23
Targeting Oxidative Stress in Neurodegenerative Disorders: A Novel Role for PCSK9 Inhibition?	23
MiR-23b-3p Improves Brain Damage after Status Epilepticus by Reducing the Formation of Pathological High-Frequency Oscillations via Inhibition of cx43 in Rat Hippocampus	23
Distinct Cholesterol Localization in Glioblastoma Multiforme Revealed by Mass Spectrometry Imaging	23
Covalent Fragment Inhibits RhoA Activation by Guanine Exchange Factors	23
Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues	22
A Synthetically Accessible Small-Molecule Inhibitor of USP5-Cav3.2 Calcium Channel Interactions with Analgesic Properties	22
Dysregulated Neurotransmission and the Role of Viruses in Alzheimer’s Disease	22
Identification of a Lipid-Exposed Extrahelical Binding Site for Positive Allosteric Modulators of the Dopamine D₂ Receptor	22
Ketogenic Diet for Neonatal Hypoxic–Ischemic Encephalopathy	22
Age-Related Neurometabolomic Signature of Mouse Brain	22
Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor	22
Dopamine Release Impairments Accompany Movement Vigor Deficiency in an Exercise-Induced Fatigue Mouse Model	22
On the Tracks of the Aggregation Mechanism of the PHF6 Peptide from Tau Protein: Molecular Dynamics, Energy, and Interaction Network Investigations	21
Phytic Acid Maintains Peripheral Neuron Integrity and Enhances Survivability against Platinum-Induced Degeneration via Reducing Reactive Oxygen Species and Enhancing Mitochondrial Membrane Potential	21
Prenatal Sevoflurane Exposure Impairs the Learning and Memory of Rat Offspring via HMGB1-Induced NLRP3/ASC Inflammasome Activation	21
Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology	21
Luminescent PLGA Nanoparticles for Delivery of Darunavir to the Brain and Inhibition of Matrix Metalloproteinase-9, a Relevant Therapeutic Target of HIV-Associated Neurological Disorders	21
Myricetin Restores Aβ-Induced Mitochondrial Impairments in N2a-SW Cells	21
Empirical Analysis of Drug Targets for Nervous System Disorders	20
Bcl-2-Homology-Only Proapoptotic Peptides Modulate β-Amyloid Aggregation and Toxicity	20
Automated, Transferable, and Ethanol-Free Radiosynthesis of [¹¹C]Butanol	20
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of Neurodegeneration	20
Effect of Cannabidiol on the Neural Glyoxalase Pathway Function and Longevity of Several C. elegans Strains Including a C. elegans Alzheimer’s Disease Model	20
Monitoring Molecules in Neuroscience	20
Issue Publication Information	20
Divergent Age-Dependent Conformational Rearrangement within Aβ Amyloid Deposits in APP23, APPPS1, and App^NL-F Mice	20
Issue Editorial Masthead	20
Lipopolysaccharide Effects on Neurotransmission: Understanding Implications for Depression	20
Chemical Perspective of the Mechanism of Action of Antiamyloidogenic Compounds Using a Minimalistic Peptide as a Reductionist Model	20
Prussian Blue Nanozyme Treatment of Ischemic Brain Injury via Reducing Oxidative Stress Inhibits Inflammation, Suppresses Apoptosis, and Promotes Neurological Recovery	19
Small-Molecule Cdc25A Inhibitors Protect Neuronal Cells from Death Evoked by NGF Deprivation and 6-Hydroxydopamine	19
New Blood–Brain Barrier Models Using Primary Parkinson’s Disease Rat Brain Endothelial Cells and Astrocytes for the Development of Central Nervous System Drug Delivery Systems	19
Modulation of α-Synuclein Fibrillation and Toxicity by 4-Phenylbutyric Acid	19
An S-Shaped Aβ42 Cross-β Hexamer Embedded into a Lipid Bilayer Reveals Membrane Disruption and Permeability	19
Glial Cells and Itch: Possible Targets for Novel Antipruritic Therapies	19
Identifying an Optimal Neuroinflammation Treatment Using a Nanoligomer Discovery Engine	19
Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity	19
Classics in Chemical Neuroscience: Tianeptine	18
Issue Editorial Masthead	18
Issue Publication Information	18
Polyaniline-Conjugated Boron Nitride Nanoparticles Exhibiting Potent Effects against Pathogenic Brain-Eating Amoebae	18
Design and Development of Benzothiazole-Based Fluorescent Probes for Selective Detection of Aβ Aggregates in Alzheimer’s Disease	18
Ratiometric Fluorescent Probe Promotes Trans-differentiation of Human Mesenchymal Stem Cells to Neurons	18
Neuropathological Effects of Chemotherapeutic Drugs	18
Deciphering the Inhibitory Mechanism of ALS-Associated N352S and S352p Variants against TDP-43 Aggregation and Its Destabilization Effect on TDP-43 Protofibrils	18
Strategic Design of Amyloid-β Species Fluorescent Probes for Alzheimer’s Disease	18
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide	18
Ascaris suum Informs Extrasynaptic Volume Transmission in Nematodes	18
Characterization of the Novel P2X7 Receptor Radioligand [³H]JNJ-64413739 in Human Brain Tissue	18
Neuroprotective Effect of Withaferin Derivatives toward MPP⁺ and 6-OHDA Toxicity to Dopaminergic Neurons	18
Cardiac Sympathetic Positron Emission Tomography Imaging with Meta-[¹⁸F]Fluorobenzylguanidine is Sensitive to Uptake-1 in Rats	18
Edge Substitution Effects of Histidine Tautomerization Behaviors on the Structural Properties and Aggregation Properties of Aβ(1–42) Mature Fibril	17
Issue Publication Information	17
Issue Editorial Masthead	17
Issue Editorial Masthead	17
Issue Publication Information	17
Issue Editorial Masthead	17
Guanidine Derivative ADS1017, a Potent Histamine H₃ Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile	17
Issue Editorial Masthead	17
Issue Publication Information	17
Issue Editorial Masthead	17
Short-Term Administration of Common Anesthetics Does Not Dramatically Change the Endogenous Peptide Profile in the Rat Pituitary	17
Proteome Aggregation in Cells Derived from Amyotrophic Lateral Sclerosis Patients for Personalized Drug Evaluation	17
Issue Editorial Masthead	17
Synthesis and Preclinical Evaluation of 22-[¹⁸F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake Kinetics	17
Deciphering the Role of Fluctuation Dependent Intercellular Communication in Neural Stem Cell Development	17
Issue Publication Information	17
Identification of a Novel Allosteric Site at the M₅Muscarinic Acetylcholine Receptor	17
Dopaminergic Modulation and Computational ADMET Insights for the Antidepressant-like Effect of N-(3-(Phenylselanyl)prop-2-yn-1-yl)benzamide	17
Saroglitazar Enhances Memory Functions and Adult Neurogenesis via Up-Regulation of Wnt/β Catenin Signaling in the Rat Model of Dementia	17
Determination of Trends Underlying Aspartic Acid Isomerization in Intact Proteins Reveals Unusually Rapid Isomerization of Tau	17
Kinesin Nanomotors Mediated Trafficking of NMDA-Loaded Cargo as A Novel Target in Chronic Pain	17
Linking the Triad of Telomere Length, Inflammation, and Gut Dysbiosis in the Manifestation of Depression	16
Neurotrophic Activity and Its Modulation by Zinc Ion of a Dimeric Peptide Mimicking the Brain-Derived Neurotrophic Factor N-Terminal Region	16

Single-Molecule Fingerprinting Reveals Different Growth Mechanisms in Seed Amplification Assays for Different Polymorphs of α-Synuclein Fibrils	16
Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model	16
Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress	16
Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization	16
Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson’s Disease	16
Melatonin Relieves Paclitaxel-Induced Neuropathic Pain by Regulating pNEK2-Dependent Epigenetic Pathways in DRG Neurons	16
DARK Classics in Chemical Neuroscience: Loperamide	16
Deciphering the Inhibitory Mechanism of Naphthoquinone–Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6	16
Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics	16
Benzo[d]imidazole-pyrrolo[1,2-a]pyrazine Hybrids Ameliorate Amyloid Aggregates in the Brain of Alzheimer Transgenic Mice	16
Understanding the Inhibitory and Antioxidant Effects of Pyrroloquinoline Quinone (PQQ) on Copper(II)-Induced α-Synuclein-119 Aggregation	16
Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach	16
Discovery of Pre-Clinical Candidate VU6008055/AF98943: A Highly Selective, Orally Bioavailable, and Structurally Distinct Tricyclic M₄ Muscarinic Acetylcholine Receptor Positi	16
Fustin Inhibits Oxidative Free Radicals and Inflammatory Cytokines in Cerebral Cortex and Hippocampus and Protects Cognitive Impairment in Streptozotocin-Induced Diabetic Rats	15
Correction to “Dexmedetomidine Attenuates Neuroinflammation-Mediated Hippocampal Neurogenesis Impairment in Sepsis-Associated Encephalopathy Mice through Central α2A-Adrenoceptor”	15
Monitoring Fast Synaptic Transmission of Neuromodulatory Transmitters To Define Drug Effects in the Brain	15
In Vitro and In Silico Analysis of the Residence Time of Serotonin 5-HT₇ Receptor Ligands with Arylpiperazine Structure: A Structure–Kinetics Relationship Study	15
Regulation of Dopamine Release by Tonic Activity Patterns in the Striatal Brain Slice	15
TMEM106B Fibrils from FTLD Patients and Healthy Controls	15
Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression	15
Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands	15
Design, Synthesis, and Pharmacological Evaluation of N-Propargylated Diphenylpyrimidines as Multitarget Directed Ligands for the Treatment of Alzheimer’s Disease	15
Hemispheric Utilization of Alpha Oscillatory Dynamics as a Unique Biomarker of Neural Compensation in Females with Fragile X Syndrome	15
Optical Precise Ablation of Targeted Individual Neurons In Vivo	15
NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?	15
Role of Imaging Modalities and N-Acetylcysteine Treatment in Sepsis-Associated Encephalopathy	15
New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold	15
¹H NMR Metabolomics and Lipidomics To Monitor Positive Responses in Children with Autism Spectrum Disorder Following a Guided Parental Intervention: A Pilot Study	15
Family of Structurally Related Bioconjugates Yields Antibodies with Differential Selectivity against Ketamine and 6-Hydroxynorketamine	15
Cooperativity of α-Synuclein Binding to Lipid Membranes	15
Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis	15
New Insights on Protein Folding and Misfolding: Histidine Behaviors	15
Issue Publication Information	15
Red-Light-Photosensitized Tyrosine 10 Nitration of β-Amyloid_1–42 Diverts the Protein from Forming Toxic Aggregates	15
Repurposing of the PET Probe Prototype PiB for Label and Radiation-Free CEST MRI Molecular Imaging of Amyloid	14
Dynamic and Rapid Detection of Guanosine during Ischemia	14
Understanding Neuropeptide Transmission in the Brain by Optical Uncaging and Release	14
DARK Classics in Chemical Neuroscience: Bucinnazine	14
Dysregulation of Neuropeptide and Tau Peptide Signatures in Human Alzheimer’s Disease Brain	14
Unraveling the Connection of Epstein–Barr Virus and Its Glycoprotein M_146–157 Peptide with Neurological Ailments	14
A Transcription Factor ZNF384, Regulated by LINC00265, Activates the Expression of IFI30 to Stimulate Malignant Progression in Glioma	14
Pharmacological Mechanism of the Non-hallucinogenic 5-HT_2A Agonist Ariadne and Analogs	14
Molecular Insights into the Dynamics of Amyloid Fibril Growth: Elongation and Lateral Assembly of GNNQQNY Protofibrils	14
Issue Publication Information	14
Issue Editorial Masthead	14
Exploring the Therapeutic Potential of Benfotiamine in a Sporadic Alzheimer’s-Like Disease Rat Model: Insights into Insulin Signaling and Cognitive function	14
Potential of ADAM 17 Signal Peptide To Form Amyloid Aggregates in Vitro	14
In Vitro and In Vivo Investigations of Chromone Derivatives as Potential Multitarget-Directed Ligands: Cognitive Amelioration Utilizing a Scopolamine-Induced Zebrafish Model	14
Shared and Unique Disease Pathways in Amyotrophic Lateral Sclerosis and Parkinson’s Disease Unveiled in Peripheral Blood Mononuclear Cells	14
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease	14
Microscopic Characterization of the Chloride Permeation Pathway in the Human Excitatory Amino Acid Transporter 1 (EAAT1)	14
Osmoregulatory Role of Betaine and Betaine/γ-Aminobutyric Acid Transporter 1 in Post-Traumatic Syringomyelia	14
Issue Editorial Masthead	14
Substrate Selection Criteria in Regulated Intramembrane Proteolysis	14
Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3β at Thr252 by in Vitro Studies	14
Observation of α-Synuclein Preformed Fibrils Interacting with SH-SY5Y Neuroblastoma Cell Membranes Using Scanning Ion Conductance Microscopy	14
The Interplay between MiR-134/BDNF and LKB1/AMPK/SIRT1 Accentuates the Antidepressant Efficacy of Empagliflozin in Ovariectomized Rats	14
Allopregnanolone Regulation of Phasic Dopamine Release and Motivated Behavior	14
Serotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice	14
Bidirectional Responses of Eight Neuroinflammation-Related Transcriptional Factors to 64 Flavonoids in Astrocytes with Transposable Insulated Signaling Pathway Reporters	14
Underlying Causes and Treatment Modalities for Neurological Deficits in COVID-19 and Long-COVID	14
Bicuculline and Bumetanide Attenuate Sevoflurane-Induced Impairment of Myelination and Cognition in Young Mice	14
Issue Editorial Masthead	14
Myricetin: A Potent Anti-Amyloidogenic Polyphenol against Superoxide Dismutase 1 Aggregation	13
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation	13
Formation of Calprotectin Inhibits Amyloid Aggregation of S100A8 and S100A9 Proteins	13
Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage	13
Compensatory Contextual Fear Memory Pathways Develop in the Infralimbic Cortex within 3 Days after the First Test in the Absence of the Dorsal Hippocampus	13
Neuralized1-Mediated CPEB3 Ubiquitination in the Spinal Dorsal Horn Contributes to the Pathogenesis of Neuropathic Pain in Rats	13
Functional Characterization of an Arylsulfonamide-Based Small-Molecule Inhibitor of the NLRP3 Inflammasome	13
Glycation Produces Topologically Different α-Synuclein Oligomeric Strains and Modulates Microglia Response via the NLRP3-Inflammasome Pathway	13
Key Residue for Aggregation of Amyloid-β Peptides	13
Biophysical Characterization and Preformulation Studies of Human Mesencephalic Astrocyte-Derived Neurotropic Factor	13
Activation Pathways of Neurotensin Receptor 1 Elucidated Using Statistical Machine Learning	13
Comprehensive Characterization of a Systematic Library of Alkyl and Alicyclic Synthetic Cannabinoids Related to CUMYL-PICA, CUMYL-BUTICA, CUMYL-CBMICA, and CUMYL-PINACA	13
Impact of Indole Inclusion in the Design of Multi-Tactical Metal-Binding Tetra-Aza Macrocycles that Target the Molecular Features of Neurodegeneration	13
Characterization of (R)- and (S)-[¹⁸F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Rec	13
Multivalent Gd-DOTA Decorated Oligopeptide as Sensitive MRI Molecular Probes for In Vivo Imaging of Brain Connectivity	13
Haloperidol Prevents Oxytosis/Ferroptosis by Targeting Lysosomal Ferrous Ions in a Manner Independent of Dopamine D2 and Sigma-1 Receptors	13
4-Amino-3′,4′-dihydroxychalcone Increases Tau Dynamics in Phase-Separated Droplets and Inhibits Tau Aggregation	13
Atomic Force Microscopy Applied to the Study of Tauopathies	13
Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice	13
Effects of Anesthetic Administration on Rat Hypothalamus and Cerebral Cortex Peptidome	13
Comparing Brain and Blood Lipidome Changes following Single and Repetitive Mild Traumatic Brain Injury in Rats	13
Ferroptosis Regulated by 5-HT3a Receptor via Calcium/Calmodulin Signaling Contributes to Neuropathic Pain in Brachial Plexus Avulsion Rat Models	13
Issue Editorial Masthead	13
Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent Neurosteroids	12
Role of Hydrophobicity at the N-Terminal Region of Aβ42 in Secondary Nucleation	12
Comprehensive Assessment of Ischemic Stroke in Nonhuman Primates: Neuroimaging, Behavioral, and Serum Proteomic Analysis	12
Sulfamerazine as a Potential Modulator against α-Synuclein Aggregation and Associated Toxicity	12
Evaluating the Neuroprotective Potential of Novel Benzodioxole Derivatives in Parkinson’s Disease via AMPA Receptor Modulation	12
4-Acyl-3,4-dihydropyrrolo[1,2-a]pyrazine Derivative Rescued the Hippocampal-Dependent Cognitive Decline of 5XFAD Transgenic Mice by Dissociating Soluble and Insoluble Aβ Aggregates	12
Quantitative Analysis of Neuropeptide Y (NPY) and C-Terminal Glycine-Extended NPY by Mass Spectrometry and Their Localization in the Developing and Sexual Adult Mouse Brains	12
Cross-Interactions of Aβ Peptides Implicated in Alzheimer’s Disease Shape Amyloid Oligomer Structures and Aggregation	12
Dexamethasone-Enhanced Continuous Online Microdialysis for Neuromonitoring of O₂ after Brain Injury	12