OOIR: Observatory of International Research

Papers

(The H4-Index of Gut Microbes is 81. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Akkermansia muciniphila reduces susceptibility to Listeria monocytogenes infection in mice fed a high-fat diet	439
L. rhamnosus CNCM I-3690 survival, adaptation, and small bowel microbiome impact in human	394
Children’s gut microbiota predicts the efficacy of obesity treatment	376
Antigenic operon fragmentation and diversification mechanism in Bacteroidota impacts gut metagenomics and pathobionts in Crohn's disease microlesions	316
Lactococcus lactis subsp. Cremoris reprograms systemic metabolism and protects against myocardial injury	265
Microbial shifts in early life: the pediatric gut microbiome and its role in health and disease	256
Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity	217
Decoding the HMO‒microbiome axis: bridging maternal milk to infant health outcomes	214
A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring	207
Intratumor Lactobacillus drives ferroptosis resistance via D-lactate-STAT3 K631 lactylation in esophageal squamous cell carcinoma	206
Contrasting dietary patterns remodel gut microbial function and generate multi-omic signatures associated with cardiometabolic markers	198
Effect of diet on the evolution of gut commensal bacteria	196
Opioid-induced dysbiosis of maternal gut microbiota during gestation alters offspring gut microbiota and pain sensitivity	176
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase	164
Clostridioides difficile aggravates dextran sulfate solution (DSS)-induced colitis by shaping the gut microbiota and promoting neutrophil recruitment	160
Pasteurized Akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice	156
Gut microbiota in nonalcoholic fatty liver disease: a PREDIMED-Plus trial sub analysis	148
Salmonella exploits a quorum-sensing family signal of the gut commensal Stenotrophomonas maltophilia to facilitate its coloniz	147
Gut microbes mediate the synergistic effects of dietary cholesterol and saturated fat in driving fibrosing MASH	147
Depletion of butyrate-producing microbes of the Firmicutes predicts nonresponse to FMT therapy in patients with recurrent Clostridium difficile infection	145
Modeling spatial interaction networks of the gut microbiota	140
Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiome	140
Ecological restructuring of the nonbacterial fecal microbiome in obesity across human cohorts	139
Gut microbiota and tuberculosis infection: interaction and therapeutic potential	138
Intestinal TLR4 deletion exacerbates acute pancreatitis through gut microbiota dysbiosis and Paneth cells deficiency	136

Linking serum vitamin D levels with gut microbiota after 1-year lifestyle intervention with Mediterranean diet in patients with obesity and metabolic syndrome: a nested cross-sectional and prospective	131
Faecal (or intestinal) microbiota transplant: a tool for repairing the gut microbiome	129
Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion	129
The ladder of regulatory stringency and balance: an application to the US FDA’s regulation of bacterial live therapeutics	129
Intestinal bacteria and colorectal cancer: etiology and treatment	129
Bile salt hydrolase activity as a rational target for MASLD therapy	126
Late-onset sepsis treatment in very preterm infants alters longitudinal microbiome trajectory with lower abundance of Bifidobacterium despite probiotic s	125
The gut-joint axis mediates the TNF-induced RA process and PBMT therapeutic effects through the metabolites of gut microbiota	122
Exercise improves gut microbial metabolites in an intensity-dependent manner: a pooled analysis of randomized controlled trials	119
Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant mice	118
Escherichia coli triggers α-synuclein pathology in the LRRK2 transgenic mouse model of PD	118
3'-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain f	116
Metabolic modeling links gut microbiota to metabolic markers of Parkinson’s disease	114
Gut microbial features and dietary fiber intake predict gut microbiota response to resistant starch supplementation	113
Microbiota during pregnancy and early life: role in maternal−neonatal outcomes based on human evidence	112
Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values	112
Meta-analysis reveals Helicobacter pylori mutual exclusivity and reproducible gastric microbiome alterations during gastric carcinoma progression	111
Gut microbiota metabolite indole-3-acetic acid maintains intestinal epithelial homeostasis through mucin sulfation	107
Maternal gut microbiota mediates prenatal stress-induced fetal blood‒brain barrier dysfunction	107
Microbial extracellular vesicles from min pigs remodel macrophage polarization via STING to sustain intestinal immune homeostasis	107
Comparison of gnotobiotic communities reveals milk-adapted metabolic functions and unexpected amino acid metabolism by the pre-weaning microbiome	105
Feeding microbes to feed the Gut: inulin reprograms intestinal epithelial metabolism and proliferation through HIF1α	104
The gut microbiome in graft-versus-host disease: mechanisms of immune modulation and therapeutic approaches	102
Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection	101
mbSparse: an autoencoder-based imputation method to address sparsity in microbiome data	100
Unraveling multiple sclerosis: a hidden interaction between intestinal microbiota and host lipid metabolism	100
Gut microbiome diversity, variability, and latent community types compared with shifts in body weight during the freshman year of college in dormitory-housed adolescents	100
Obesity is the main driver of altered gut microbiome functions in the metabolically unhealthy	99
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic-associated fatty liver disease	98
Multi-strain probiotics during pregnancy in women with obesity influence infant gut microbiome development: results from a randomized, double-blind placebo-controlled study	97
The Fe-S cluster biosynthesis in Enterococcus faecium is essential for anaerobic growth and gastrointestinal colonization	97
Role and mechanism of gut microbiota and metabolites in schizophrenia complicated with sleep disorder	96
The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity	95
Citrobacter rodentium possesses a functional type II secretion system necessary for successful host infection	94
Immunoglobulin A protease from Sutterella wadsworthensis modifies outcome of infection with Campylobacter jejuni	94
Proton pump inhibitors are not associated with an increased risk of Clostridioides difficile infection: a systematic review and meta-analysis of randomiz	93
Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection	91
The microbiota and the host organism switch between cooperation and competition based on dietary iron levels	91
Gluten-free diet affects fecal small non-coding RNA profiles and microbiome composition in celiac disease supporting a host-gut microbiota crosstalk	91
Gut microbiota and radiation-induced injury: mechanistic insights and microbial therapies	91
High throughput genome scale modeling predicts microbial vitamin requirements contribute to gut microbiome community structure	90
Helicobacter pylori activates histone lactylation to promote gastric cancer progression and immune evasion through the HAS2/c-MYC/PD-L1 axis	89
Exploring the gut microbiome and metabolomic interactions of antimetabolite drugs to optimize therapy	89
Engineered bacteria as an orally administered anti-viral treatment and immunization system	88
The regulatory effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the mechanism behind Candida albicans	88
The emerging role of the gut microbiota in vaccination responses	88
The intestinal microbiome of inflammatory bowel disease across the pediatric age range	86
Gut microbiota-mediated conversion of mangiferin to norathyriol alters short chain fatty acid and urate metabolism	86
Assessing the proinflammatory potential of sterile fecal microbiome filtrate from ulcerative colitis patients using an intestine-on-chip platform and automated image analysis	86
Gut microbiota drives structural variation of exogenous probiotics to enhance colonization	86

Microbial metabolite Urolithin A protects against inorganic arsenic-induced gut barrier dysfunction in humanized AS3MT mice	86
Long COVID and gut microbiome: insights into pathogenesis and therapeutics	85
Maternal milk fat globule membrane enriched gut L. murinus and circulating SCFAs to improve placental efficiency and fetal development in intrauterine gr	85
Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice	84
Therapeutic potential of Clostridium butyricum anticancer effects in colorectal cancer	82
Advances in the acting mechanism and treatment of gut microbiota in metabolic dysfunction-associated steatotic liver disease	82
Regulation of flagellar motility and biosynthesis in enterohemorrhagic Escherichia coli O157:H7	81