OOIR: Observatory of International Research

Papers

(The H4-Index of Gut Microbes is 71. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
The gut-joint axis mediates the TNF-induced RA process and PBMT therapeutic effects through the metabolites of gut microbiota	339
Modeling spatial interaction networks of the gut microbiota	316
A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring	315
Late-onset sepsis treatment in very preterm infants alters longitudinal microbiome trajectory with lower abundance of Bifidobacterium despite probiotic s	255
Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiome	244
Antigenic operon fragmentation and diversification mechanism in Bacteroidota impacts gut metagenomics and pathobionts in Crohn's disease microlesions	197
Intestinal TLR4 deletion exacerbates acute pancreatitis through gut microbiota dysbiosis and Paneth cells deficiency	197
Meta-analysis reveals Helicobacter pylori mutual exclusivity and reproducible gastric microbiome alterations during gastric carcinoma progression	191
Gut microbiota and tuberculosis infection: interaction and therapeutic potential	187
Exercise improves gut microbial metabolites in an intensity-dependent manner: a pooled analysis of randomized controlled trials	167
The ladder of regulatory stringency and balance: an application to the US FDA’s regulation of bacterial live therapeutics	166
Dietary fiber-based regulation of bile salt hydrolase activity in the gut microbiota and its relevance to human disease	159
Microbial succinate promotes the response to metformin by upregulating secretory immunoglobulin a in intestinal immunity	158
Gut microbial features and dietary fiber intake predict gut microbiota response to resistant starch supplementation	154
Effect of diet on the evolution of gut commensal bacteria	151
Metabolic modeling links gut microbiota to metabolic markers of Parkinson’s disease	140
Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion	132
Limosilactobacillus reuteri DS0384 promotes intestinal epithelial maturation via the postbiotic effect in human intestinal organoids and infant mice	131
Microbiota during pregnancy and early life: role in maternal−neonatal outcomes based on human evidence	131
Pasteurized Akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice	128
Linking serum vitamin D levels with gut microbiota after 1-year lifestyle intervention with Mediterranean diet in patients with obesity and metabolic syndrome: a nested cross-sectional and prospective	127
Opioid-induced dysbiosis of maternal gut microbiota during gestation alters offspring gut microbiota and pain sensitivity	117
L. rhamnosus CNCM I-3690 survival, adaptation, and small bowel microbiome impact in human	117
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase	112
3'-Sialyllactose and B. infantis synergistically alleviate gut inflammation and barrier dysfunction by enriching cross-feeding bacteria for short-chain f	112

Clostridioides difficile aggravates dextran sulfate solution (DSS)-induced colitis by shaping the gut microbiota and promoting neutrophil recruitment	110
Escherichia coli triggers α-synuclein pathology in the LRRK2 transgenic mouse model of PD	107
Faecal (or intestinal) microbiota transplant: a tool for repairing the gut microbiome	106
Intestinal bacteria and colorectal cancer: etiology and treatment	103
Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells	101
Gut microbiota metabolite indole-3-acetic acid maintains intestinal epithelial homeostasis through mucin sulfation	99
Progress of linking gut microbiota and musculoskeletal health: casualty, mechanisms, and translational values	99
Depletion of butyrate-producing microbes of the Firmicutes predicts nonresponse to FMT therapy in patients with recurrent Clostridium difficile infection	98
Akkermansia muciniphila reduces susceptibility to Listeria monocytogenes infection in mice fed a high-fat diet	97
Gut microbiota in nonalcoholic fatty liver disease: a PREDIMED-Plus trial sub analysis	96
Gut microbiome diversity, variability, and latent community types compared with shifts in body weight during the freshman year of college in dormitory-housed adolescents	96
Long COVID and gut microbiome: insights into pathogenesis and therapeutics	95
Therapeutic potential of Clostridium butyricum anticancer effects in colorectal cancer	95
Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice	95
The microbiota and the host organism switch between cooperation and competition based on dietary iron levels	95
Multi-strain probiotics during pregnancy in women with obesity influence infant gut microbiome development: results from a randomized, double-blind placebo-controlled study	94
Antidepressant drugs promote the spread of broad-host-range plasmid in mouse and human gut microbiota	92
In vivo systematic analysis of microbiota-prebiotic crosstalk reveals a synbiotic that effectively ameliorates DSS-induced colitis in mice	92
Next-generation probiotics – do they open new therapeutic strategies for cancer patients?	90
MS-20 enhances the gut microbiota-associated antitumor effects of anti-PD1 antibody	90
Regulation of flagellar motility and biosynthesis in enterohemorrhagic Escherichia coli O157:H7	89
Arginine-mediated gut microbiome remodeling promotes host pulmonary immune defense against nontuberculous mycobacterial infection	89
The Fe-S cluster biosynthesis in Enterococcus faecium is essential for anaerobic growth and gastrointestinal colonization	89
Obesity enriches for tumor protective microbial metabolites and treatment refractory cells to confer therapy resistance in PDAC	88
High throughput genome scale modeling predicts microbial vitamin requirements contribute to gut microbiome community structure	86
Comparison of gnotobiotic communities reveals milk-adapted metabolic functions and unexpected amino acid metabolism by the pre-weaning microbiome	84
Citrobacter rodentium possesses a functional type II secretion system necessary for successful host infection	84
Acids produced by lactobacilli inhibit the growth of commensal Lachnospiraceae and S24-7 bacteria	83
Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection	81
Communication between the gut microbiota and peripheral nervous system in health and chronic disease	80
Gut microbiota-mediated conversion of mangiferin to norathyriol alters short chain fatty acid and urate metabolism	79
Dysbiotic but nonpathogenic shift in the fecal mycobiota of patients with rheumatoid arthritis	79
Gut microbiota and radiation-induced injury: mechanistic insights and microbial therapies	77
The emerging role of the gut microbiota in vaccination responses	77
The crystal structure of the toxin EspC from enteropathogenic Escherichia coli reveals the mechanism that governs host cell entry and cytotoxicity	76
mbSparse: an autoencoder-based imputation method to address sparsity in microbiome data	76
Proton pump inhibitors are not associated with an increased risk of Clostridioides difficile infection: a systematic review and meta-analysis of randomiz	75
Maternal milk fat globule membrane enriched gut L. murinus and circulating SCFAs to improve placental efficiency and fetal development in intrauterine gr	75
Unraveling multiple sclerosis: a hidden interaction between intestinal microbiota and host lipid metabolism	75
The regulatory effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the mechanism behind Candida albicans	75
Obesity is the main driver of altered gut microbiome functions in the metabolically unhealthy	73
Gluten-free diet affects fecal small non-coding RNA profiles and microbiome composition in celiac disease supporting a host-gut microbiota crosstalk	72
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic-associated fatty liver disease	72
Ethanol-induced changes to the gut microbiome compromise the intestinal homeostasis: a review	72
Engineered bacteria as an orally administered anti-viral treatment and immunization system	71
Efficacy of fecal microbiota transplantation in patients with Parkinson’s disease: clinical trial results from a randomized, placebo-controlled design	71
Role and mechanism of gut microbiota and metabolites in schizophrenia complicated with sleep disorder	71