OOIR: Observatory of International Research

Papers

(The median citation count of Biochip Journal is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
One-Step Evaluation of Doxorubicin Toxicity Through Concentration Gradient Generator Integrating Breast Cancer-on-a-Chip	83
Flexible Polytetrafluoroethylene (PTFE) Tube-Based Curved Serpentine Micromixer Guided by 3D-Printed Frames	60
Modeling Preeclampsia: From 2D Cultures to Placenta-on-a-Chip Technologies	57
Additive Manufacturing a One-Piece Microfluidic Device Coupled to Liquid Chromatography–Mass Spectrometry for In Vitro Drug Metabolism Analysis	43
Transdermal Drug Delivery System Using Light and Moisture Dual Responsive Hybrid Microneedles	38
An Integrated Electrochemical Sensor with Flexible Microfluidic Structures for Human Sweat Analysis	38
Recording Fast Ion Channel Kinetics Using Non-invasive Electrical Impedance Spectroscopy	38
Immunogenicity Monitoring Cell Chip Incorporating Finger-Actuated Microfluidic and Colorimetric Paper-Based Analytical Functions	37
Effect of Food Sensitivity on Overweight Assessed Using Food-Specific Serum Immunoglobulin G Levels	36
Ultraviolet Fluorescence-Based Quantitative Detection of Polycyclic Aromatic Hydrocarbons	34
Microfabricated Stretching Devices for Studying the Effects of Tensile Stress on Cells and Tissues	33
A Laser-Micromachined PCB Electrolytic Micropump Using an Oil-Based Electrolyte Separation Barrier	30
Real-Time Detection of SARS-CoV-2 Nucleocapsid Antigen Using Data Analysis Software and IoT-Based Portable Reader with Single-Walled Carbon Nanotube Field Effect Transistor	29
Non-invasive Thermohydrodynamic Approach for Fast Cell Manipulation at the Microscale	28
Classification of DNA Mixtures by Nanoelectrokinetic Driftless Preconcentration	28
Microfluidic Capture Device for Simple, Cell Surface Marker-Based Quantification of Senescent CD8+ T Cells	26
Acoustofluidic Microbioreactor Using Surface Acoustic Wave-induced Acoustic Streaming Flow	25
Development of Multi-HRP-Conjugated Branched PEI/Antibody-Functionalized Gold Nanoparticles for Ultra-Sensitive ELISA	24
Electrochemical Microbiosensor for Detecting COVID-19 in a Patient Sample Based on Gold Microcuboids Pattern	23
Target-Responsive Template Structure Switching-Mediated Exponential Rolling Circle Amplification for the Direct and Sensitive Detection of MicroRNA	22
Isolation of Antibodies Against the Spike Protein of SARS-CoV from Pig Serum for Competitive Immunoassay	22
SF-qPCR: Strand Displacement-Based Fast Quantitative Polymerase Chain Reaction	22
Recent Developments in Surface Topography-Modulated Neurogenesis	21
Mechanically Flexible Polymeric Nanoneedle Arrays for Promoting Differentiation and Functional Activity of Neural Progenitor Cells	20
Recent Developments in MXene-Based Enzyme-Free Electrochemical Glucose Sensing	19

Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling	19
DNA–Gold Nanoparticle Conjugates for Intracellular miRNA Detection Using Surface-Enhanced Raman Spectroscopy	18
Pressed Lateral Flow Assay Strips for Flow Delay-Induced Signal Enhancement in Lateral Flow Assay Strips	18
Microfluidic Device to Maximize Capillary Force Driven Flows for Quantitative Single-Molecule DNA Analysis	17
Fluorescent Lateral Flow Assay with Carbon Nanodot Conjugates for Carcinoembryonic Antigen	17
Nanomaterials-Based Exosomes for the Diagnostics and Drug Deliveries of Central Nervous System Diseases	16
Laser-Assisted Recovery of On-Chip Phage Viral DNA for Phage Fluorescence Immunoassay Microchip	16
Nanoplasmonic Sensor Chip Readable in a Conventional Plate Reader	15
Recent Developments in 3D Printing of Droplet-Based Microfluidics	15
Validation of Nephrotoxicity Suppression by SGLT-2 Inhibitors Using the Kidney-on-a-Chip Model	14
Automated Sample Treatment System for Enhanced Molecular Pathogen Detection in Blood	14
Ultrasensitive Detection of Ovarian Cancer Biomarker Using Au Nanoplate SERS Immunoassay	13
Recent Advances in Electrochemical and Optical Biosensors for Cancer Biomarker Detection	13
Portable Au Nanoparticle-Based Colorimetric Sensor Strip for Rapid On-Site Detection of Cd2+ Ions in Potable Water	13
The Novel Membrane-Type Micro-system to Assess the Bonus Effect of Physiological and Physical Stimuli on Bone Regeneration	13
3D Artificial Cell Membranes as Versatile Platforms for Biological Applications	12
Enzymatic Reaction Automation in Nanodroplet Microfluidic for the Quality Control of Monoclonal Antibodies	12
Recent Progress in Rapid Biosensor Fabrication Methods: Focus on Electrical Potential Application	12
Numerical-Simulation-Based Buffer Design for Microchip Electrophoresis with Capacitively Coupled Contactless Conductivity Detection	11
Multi-layered Microfluidic Drug Screening Platform Enabling Simultaneous Generation of Linear and Logarithmic Concentration Gradients	11
Colorimetric Detection of Staphylococcus aureus Based on Direct Loop-Mediated Isothermal Amplification in Combination with Lateral Flow Assay	11
Recent Advances in 3D-Cultured Brain Tissue Models Derived from Human iPSCs	11
Analysis of Thrombosis Formation and Growth Using Microfluidic Chips and Multiphase Computational Fluid Dynamics	11
Development of an Electrochemical Biosensor for Tetrodotoxin Using Specific Binding Peptide on Polypyrrole/Au Nanoparticle-Modified Electrodes	10
Enhancement of Overlimiting Current in a Three-Dimensional Hierarchical Micro/Nanofluidic System by Non-uniform Compartmentalization	10
Advancing Blood–Brain Barrier-on-a-Chip Models Through Numerical Simulations	10
Surface Tension-Based Open Microfluidic Platform Using Micropillars to Recreate the 3D Lung Cellular Microenvironment	10
Surface Modification Strategies for Biomedical Applications: Enhancing Cell–Biomaterial Interfaces and Biochip Performances	10
Graphene Oxide-Mediated Fluorometric Aptasensor for Okadaic Acid Detection	10
Recent Developments in Innovative Magnetic Nanoparticles-Based Immunoassays: From Improvement of Conventional Immunoassays to Diagnosis of COVID-19	10
One-Step Immunoassay for the Detection of SARS-CoV-2 Nucleocapsid Protein Using Screened Fv-Antibodies	9
All-Rounder Liposomes in Cancer Immunotherapy: Strategies and Design Applications of Engineered Liposomal Nanomaterials	9
The Detection of Urinary Exosomal miRNAs for Cancer Diagnostics and Prognostics	9
Alteration of Inertial Focusing Positions in Triangular Channels Using Flexible PDMS Microfluidics	9
Fabrication of Biomimetic Cell Culture Membranes Using Robust and Reusable Nickel Micropillar Molds	9
Spheroid-Matrix Kidney-on-a-Chip Model for Predicting Drug-Induced Nephrotoxicity	9
Towards Nanomaterial-Incorporated Soft Actuators: from Inorganic/Organic Material-Based Soft Robot to Biomaterial-Based Biohybrid Robot	9
Machine Learning-Driven Electrochemical Aptasensing Platform for Highly Accurate Prediction of Phthalate Concentration in Multiple River Sites	9
Effect of Periodical Tensile Stimulation on the Human Skin Equivalents by Magnetic Stretching Skin-on-a-Chip (MSSC)	8
Paper-Based Radial Flow Assay Integrated to Portable Isothermal Amplification Chip Platform for Colorimetric Detection of Target DNA	8
Recent Advances in Photoelectrochemical Sensing of Alzheimer’s Biomarkers	8
Biological Influence of Pulmonary Disease Conditions Induced by Particulate Matter on Microfluidic Lung Chips	8
Deep Learning-Assisted Droplet Digital PCR for Quantitative Detection of Human Coronavirus	8
Low-Powered pH-Stable Nano-electrokinetically Enhanced Lateral Flow Assay for COVID-19 Antigen Test	8
Quantitative Determination of 3D-Printing and Surface-Treatment Conditions for Direct-Printed Microfluidic Devices	8
Recent Progress in High-Throughput Enzymatic DNA Synthesis for Data Storage	7
Voltammetric Aptamer-Based Biochip Featuring Poly Gallic Acid/SnO2–MoO3 Nanocomposite for Selective Tryptophan Detection: Potential Application in Alzheimer's Diagnosis	7
In Vitro Assays of Neurite Outgrowth and Synapse Formation Using Thermoplasmonic Ablation Technique	7
Synergetic Chemo-Mechano Antimicrobial Puncturable Nanostructures for Efficient Bioaerosol Removal	7
Combining Ultrasound-Mediated Intracellular Delivery with Microfluidics in Various Applications	7

Development of an Inkless, Visual Volumetric Chip Operated with a Micropipette	6
Development of a Structure-Switching Aptamer for Sensitive Colorimetric Detection of Botulinum Neurotoxin	6
Development of Tumor-Vasculature Interaction on Chip Mimicking Vessel Co-Option of Glioblastoma	5
Highly Efficient DNA Reporter for CRISPR/Cas12a-Based Specific and Sensitive Biosensor	5
Label-free Electrochemical Biosensor for Glycated Hemoglobin (HbA1c) and Glycated Albumin (GA) Measurement Using 4-mercapto-phenyl Boronic Acid Embedded Affinity	5
Single-Shot Light-Field Microscopy: An Emerging Tool for 3D Biomedical Imaging	5
Thermal-Corrosion-Free Electrode-Integrated Cell Chip for Promotion of Electrically Stimulated Neurite Outgrowth	5
Recent Advances in Microfluidic-Based Microphysiological Systems	5
Multistory Stairs-based, Fast and Point-of-care Testing for Disease Biomarker Using One-step Capillary Microfluidic Fluoroimmunoassay Chip via Continuous On-chip Labelling	5
Micro-injection Molded Droplet Generation System for Digital PCR Application	5
A Label-Free, One-Step Isothermal Assay for Sensitive Detection of Telomerase Activity Using Light-Up Aptamer	5
Human Dermal Fibroblast Spheroid Overexpressing Matrix Metalloproteinase-1 Serves as a 3D Platform for In Vitro Drug Screening	5
Rapid and Ultrasensitive Detection of Staphylococcus aureus Using a Gold-Interdigitated Single-Wave-Shaped Electrode (Au-ISWE) Electrochemical Biosensor	5
A Controlled Transcription-Driven Light-Up Aptamer Amplification for Nucleoside Triphosphate Detection	5
Biomimetic Nanopillar-Based Biosensor for Label-Free Detection of Influenza A Virus	5
Magnetic Nanochain-Based Smart Drug Delivery System with Remote Tunable Drug Release by a Magnetic Field	5
Synthesis of Truncated DNA Aptamer and Its Application to an Electrochemical Biosensor Consisting of an Aptamer and a MXene Heterolayer for Yellow Fever Virus	5
Investigation of Collagen Network Microstructure and Vascular Sprouting On-Chip Using Non-enzymatic Glycation	5