OOIR: Observatory of International Research

Papers

(The median citation count of Biochip Journal is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Microfabricated Stretching Devices for Studying the Effects of Tensile Stress on Cells and Tissues	121
A Laser-Micromachined PCB Electrolytic Micropump Using an Oil-Based Electrolyte Separation Barrier	65
Recent Advances of Concentration Gradient Microfluidic Chips for Drug Screening	52
Enhancement of Overlimiting Current in a Three-Dimensional Hierarchical Micro/Nanofluidic System by Non-uniform Compartmentalization	51
Numerical-Simulation-Based Buffer Design for Microchip Electrophoresis with Capacitively Coupled Contactless Conductivity Detection	46
Recent Advances in Electrochemical and Optical Biosensors for Cancer Biomarker Detection	46
Advancing Blood–Brain Barrier-on-a-Chip Models Through Numerical Simulations	43
Ligand-Driven Enzyme-Accelerated Signal Enhancement via Polydopamine Deposition for Visualizing Cell Receptors	43
Polymerase Elongation onto Patterned DNA for Random Accessed DNA Data Storage	37
In Vitro Assays of Neurite Outgrowth and Synapse Formation Using Thermoplasmonic Ablation Technique	36
Single-Shot Light-Field Microscopy: An Emerging Tool for 3D Biomedical Imaging	36
Deep Learning-Assisted Droplet Digital PCR for Quantitative Detection of Human Coronavirus	30
Thermoplasmonic Scaffold Design for the Modulation of Neural Activity in Three-Dimensional Neuronal Cultures	28
Nitrogen-Containing Bisphosphonate Carbon Dots with High Affinity to Calcium-Based Biomaterials for Suppression of Osteoclasts	27
Development of a 3D Vascularized Skeletal Muscle Model Using Bi-Layered Seeding Methods	26
Engineered Blood Clots for Embolization in a 3D Microfluidic Chip Model Mimicking Vascular Structures	25
Electrokinetic Paper-Based Ion Pre-concentrator for On-Site Detection of Ionic Water Contaminants	24
Helicobacter pylori-Vacuolating Cytotoxin A Induces Neurotoxic Neuroinflammation in Human Multicellular Models	24
Label-free Electrochemical Biosensor for Glycated Hemoglobin (HbA1c) and Glycated Albumin (GA) Measurement Using 4-mercapto-phenyl Boronic Acid Embedded Affinity	23
Homobifunctional Imidoester Combined Black Phosphorus Nanosheets Used as Cofactors for Nucleic Acid Extraction	21
Non-Invasive, Non-Enzymatic Glucose Sensor Using Phenylboronic Acid with Reversible Glucose Interaction	20
Plasmonic-Multichromatic Sensor for Gallic Acid Assay Utilizing Ag-Coated Au Nanobipyramids	20
DNA-Wrapped CNT Sensor for Small Nucleic Acid Detection: Influence of Short Complementary Sequence	19
A Lateral Flow Assay for Nucleic Acid Detection Based on Rolling Circle Amplification Using Capture Ligand-Modified Oligonucleotides	17
Organ-On-A-Chip Technology: An In-depth Review of Recent Advancements and Future of Whole Body-on-chip	17

Current Advances in Paper-Based Biosensor Technologies for Rapid COVID-19 Diagnosis	17
Sensitive Detection of SARS-CoV-2 Spike Protein Using an Aptamer Sandwich Assay-Based Electrochemical Biosensor	17
Establishment and Evaluation of Immunocolloidal Gold Chromatography Method in the Sandwich Mode for Novel Coronavirus Double-Antibody Detection	16
Detection and Real-Time Monitoring of LDL-Cholesterol by Redox-Free Impedimetric Biosensors	15
Enhancement of Maturation and Functionality of Human Fabry Disease Kidney Organoids in a Microfluidic Gradient Chip	15
M13 Bacteriophage-Based Bio-nano Systems for Bioapplication	15
Polydopamine Nanoparticle-Incorporated Fluorescent Hydrogel for Fluorescence Imaging-Guided Photothermal Therapy of Cancers	15
Modeling Preeclampsia: From 2D Cultures to Placenta-on-a-Chip Technologies	14
Classification of DNA Mixtures by Nanoelectrokinetic Driftless Preconcentration	14
SF-qPCR: Strand Displacement-Based Fast Quantitative Polymerase Chain Reaction	14
Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling	14
Non-invasive Thermohydrodynamic Approach for Fast Cell Manipulation at the Microscale	14
Recording Fast Ion Channel Kinetics Using Non-invasive Electrical Impedance Spectroscopy	14
Acoustofluidic Microbioreactor Using Surface Acoustic Wave-induced Acoustic Streaming Flow	14
Miniaturized and Automated Optical-Switch Raman Spectroscopy Enabling Multiwell Surface-Enhanced Raman Spectroscopy Screening More than 26,000 Wells per Day	13
One-Step Immunoassay for the Detection of SARS-CoV-2 Nucleocapsid Protein Using Screened Fv-Antibodies	13
Towards Nanomaterial-Incorporated Soft Actuators: from Inorganic/Organic Material-Based Soft Robot to Biomaterial-Based Biohybrid Robot	13
Spheroid-Matrix Kidney-on-a-Chip Model for Predicting Drug-Induced Nephrotoxicity	13
Recent Progress in Rapid Biosensor Fabrication Methods: Focus on Electrical Potential Application	13
Recent Advances in 3D-Cultured Brain Tissue Models Derived from Human iPSCs	13
Critical Challenges and Future Direction in Extracellular Vesicle Research and Commercialization	13
Synergetic Chemo-Mechano Antimicrobial Puncturable Nanostructures for Efficient Bioaerosol Removal	13
Low-Powered pH-Stable Nano-electrokinetically Enhanced Lateral Flow Assay for COVID-19 Antigen Test	13
Real-Time Detection of SARS-CoV-2 Nucleocapsid Antigen Using Data Analysis Software and IoT-Based Portable Reader with Single-Walled Carbon Nanotube Field Effect Transistor	13
SARS-CoV-2 S1-Inducing Reactive Astrocyte and Proteinopathies via TANK-Binding Kinase 1 in Human Neuroglia Model	13
Surface Modification Strategies for Biomedical Applications: Enhancing Cell–Biomaterial Interfaces and Biochip Performances	13
A Label-Free, One-Step Isothermal Assay for Sensitive Detection of Telomerase Activity Using Light-Up Aptamer	12
Functionalized Carbon Quantum Dots Derived from Zelkova serrata Plant Leaves for the Detection of Normetanephrine in Geriatric Plasma Samples and ROS-Induced Antibacterial Applications Using a Plausib	11
Continuous Isolation of Stem-Cell-Derived Extracellular Vesicles (SC-EVs) by Recycled Magnetic Beads in Microfluidic Channels	11
Fabrication of Nephrotoxic Model by Kidney-on-a-Chip Implementing Renal Proximal Tubular Function In Vitro	11
Simultaneous Triplex Detection in a Single-Test-Line Lateral Flow Immunoassay Utilizing Distinct Nanoparticle Colorimetry	11
Thermal-Corrosion-Free Electrode-Integrated Cell Chip for Promotion of Electrically Stimulated Neurite Outgrowth	11
Advancements in Kidney-on-Chip: Antibiotic-Induced Kidney Injury and Future Directions	11
Advances in Nanoparticles for Effective Delivery of RNA Therapeutics	11
Microtubule WGM Sensor: Applications and Key Technologies	10
Advances and Challenges in 3D Modelling of Organ-on-a-Chip Devices with a Focus on the Glomerular Basement Membrane (GBM) and Tubular Systems: A Critical Review	10
Zinc-Finger-Protein-Based Microfluidic Electrophoretic Mobility Reversal Assay for Quantitative Double-Stranded DNA Analysis	10
A New Quantum Dot-Based Lateral Flow Immunoassay for the Rapid Detection of Influenza Viruses	10
Oxygen-Terminated Silicon Carbide (SiC) Particle-Coated Electrodes for Highly Sensitive Electrochemical Immunoassays	10
Surface Plasmon Resonance (SPR) Biosensor for the Detection of SARS-CoV-2 Using Autodisplyaed FV-antibodies on Outer Membrane of E. coli	10
One-Step Homogeneous Immunoassay for the Detection of Influenza Virus Using Switching Peptide and Graphene Quencher	10
Development of Gut-Mucus Chip for Intestinal Absorption Study	10
High-Performance Graphene FET Integrated Front-End Amplifier Using Pseudo-resistor Technique for Neuro-prosthetic Diagnosis	10
Surface Functionalization and Bonding of Chemically Inert Parylene Microfluidics Using Parylene-A Adhesive Layer	10
Advanced Microfluidic Platform for Tumor Spheroid Formation and Cultivation Fabricated from OSTE+ Polymer	9
Fluorescent Lateral Flow Assay with Carbon Nanodot Conjugates for Carcinoembryonic Antigen	9
Recent Advances in Electrochemical and Nanophotonic Biosensors for SARS-CoV-2 Detection	9
Immunogenicity Monitoring Cell Chip Incorporating Finger-Actuated Microfluidic and Colorimetric Paper-Based Analytical Functions	9
Rapid and Cost-Effective On-site Detection of Plant Viruses Using Personal Glucose Meters Integrated with LAMP and Cascade Enzymatic Reactions	9
Target-Responsive Template Structure Switching-Mediated Exponential Rolling Circle Amplification for the Direct and Sensitive Detection of MicroRNA	9

Modular Microfluidics: A Systematic Review of Assembly-Based Categorization and Biological Applications	9
Micro-injection Molded Droplet Generation System for Digital PCR Application	8
Nanomaterials-Based Exosomes for the Diagnostics and Drug Deliveries of Central Nervous System Diseases	8
Investigation of Collagen Network Microstructure and Vascular Sprouting On-Chip Using Non-enzymatic Glycation	8
A Robust, Solvent-Resistant Paper-Based Platform for Discriminative Detection of Organic Solvents	8
Mechanically Flexible Polymeric Nanoneedle Arrays for Promoting Differentiation and Functional Activity of Neural Progenitor Cells	8
Point-of-Care Diagnostic Modular Device for Detection of VHSV with Reverse Transcription Loop-Mediated Isothermal Amplification	8
3D Artificial Cell Membranes as Versatile Platforms for Biological Applications	8
Paper-Based Radial Flow Assay Integrated to Portable Isothermal Amplification Chip Platform for Colorimetric Detection of Target DNA	7
Effect of Periodical Tensile Stimulation on the Human Skin Equivalents by Magnetic Stretching Skin-on-a-Chip (MSSC)	7
Fabrication of Biomimetic Cell Culture Membranes Using Robust and Reusable Nickel Micropillar Molds	7
Integration of Machine Learning in Surface-Enhanced Raman Spectroscopy Biosensor for Biomedical Applications	7
Voltammetric Aptamer-Based Biochip Featuring Poly Gallic Acid/SnO2–MoO3 Nanocomposite for Selective Tryptophan Detection: Potential Application in Alzheimer's Diagnosis	7
Advanced Organotypic In Vitro Model Systems for Host–Microbial Coculture	6
Stabilized Exfoliated Black Phosphorus Nanosheets for Fungal DNA-Extraction Assay	6
Intensity Histogram-Based Reliable Image Analysis Method for Bead-Based Fluorescence Immunoassay	6
Label-Free Impedance Monitoring of the Protective Effect of Salviae Miltiorrhizae Radix on Glutamate-Induced Neurotoxicity	6
Recent Advances in Microfluidic-Based Microphysiological Systems	6
Recent Trends in Biosensors Based on Electrochemical and Optical Techniques for Cyanobacterial Neurotoxin Detection	6
Nano-biomarker-Based Surface-Enhanced Raman Spectroscopy for Selective Diagnosis of Gallbladder and Liver Injury	6
Highly Efficient DNA Reporter for CRISPR/Cas12a-Based Specific and Sensitive Biosensor	6
Fabrication of Cell Spheroids for 3D Cell Culture and Biomedical Applications	5
Comparison and Analysis of Polymer-Functionalized Carbon Nanotubes for Enhancement of the Quantitative Detection of Procalcitonin Levels in Human Plasma	5
Horizontal Viscoelastic Focusing for Hyperspectral Microflow Cytometry	5
Toxicity Assessment of Humidifier Disinfectant Component CMIT/MIT Using Bioprinted Thin-Layer Human Alveolar Model	5
Optical-Switch Raman Spectroscopy for High Throughput Screening	5
Enhanced Antitumor Effect of the Combination of Bacille Calmette-Guérin and an Immune Checkpoint Inhibitor in Bladder Cancer-On-a-Chip	5
Gut-Liver-Immune Modular Multi-organ Chip for Non-alcoholic Fatty Liver Disease (NAFLD) Model	5
One-Step Immunoassay for the Detection of Influenza Virus Based on Screened Nucleoprotein (NP)-like Mimotopes from Fv-Antibody Library	5
Electrochemical Immunoassay Using Diffusion Layer Dispersion Effect of Electrodes	5
Ultraviolet Fluorescence-Based Quantitative Detection of Polycyclic Aromatic Hydrocarbons	5
Flexible Capillary Microfluidic Devices Based on Surface-Energy Modified Polydimethylsiloxane and Polymethylmethacrylate with Room-Temperature Chemical Bonding	5