OOIR: Observatory of International Research

Papers

(The TQCC of Genes & Genomics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Postoperative circulating tumor DNA detection and CBLB mutations are prognostic biomarkers for gastric cancer	28
Phosphofructokinase 1 platelet isoform induces PD-L1 expression to promote glioblastoma immune evasion	24
Profiling of testis-specific or testis-predominant genes expressed in mouse male germ cell lines GC-1 and GC-2	22
Association mapping analysis (AMA) for morpho-agronomic traits and leaf aromatic compounds using SSR markers in three types of Perilla crop collected from South Korea	21
Epigenetic reorganization during early embryonic lineage specification	20
Epigenetic inactivation of ACAT1 promotes epithelial-mesenchymal transition of clear cell renal cell carcinoma	20
Physiological and omics analysis of maize inbred lines during late grain development	19
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation	18
A rare TNNT1 gene variant causing creatine kinase elevation in nemaline myopathy: c.271_273del (p.Lys91del)	17
DNA methylome profiling of blood to identify individuals in a pair of monozygotic twins	16
Transcriptomic analysis reveal the responses of dendritic cells to VDBP	15
Phylogeography of the Korean endemic Coreoleuciscus (Cypriniformes: Gobionidae): the genetic evidence of colonization through Eurasian continent to the Korean Peninsula during Late Plio-Pleistocene	15
Gut Microbiome and colorectal cancer: discovery of bacterial changes with metagenomics application in Turkısh population	15
LncRNA SNHG20 promotes cell proliferation and invasion by suppressing miR-217 in ovarian cancer	14
SIRT3-mediated mitochondrial unfolded protein response weakens breast cancer sensitivity to cisplatin	14
Development of markers using microsatellite loci of two rove beetle species, Paederus fuscipes Curtis and Aleochara (Aleochara) curtula Goeze (Coleoptera: Staphylinidae), followed by analyses of genet	12
NEDD4L suppresses PD-L1 expression and enhances anti-tumor immune response in A549 cells	12
Discovery and genome-wide characterization of a novel miniature inverted repeat transposable element reveal genome-specific distribution in Glycine	11
RNA-binding protein expression based machine learning model predicts metastasis and treatment outcome of testicular cancer	11
Comparative whole genome analysis of face-derived Streptococcus infantis CX-4 unravels the functions related to skin barrier	11
ICT1 deficiency leads to reduced oxygen resistance due to the cell wall damage in S. cerevisiae	11
Correlation between obstructive sleep apnea and cerebral small vessel disease: a mendelian randomization study	11
UBE2C regulating the lung carcinoma progression via inhibiting ubiquitin-proteasomal degradation to increase MMP9 protein stability	10
m6A-mediated lncRNA NEAT1 plays an oncogenic role in non-small cell lung cancer by upregulating the HMGA1 expression through binding miR-361-3p	10
Rapid identification of SARS-CoV-2 in the point-of-care using digital PCR-based Dr. PCR™ Di20K COVID-19 Detection Kit without viral RNA extraction	10

FK866 inhibits colorectal cancer metastasis by reducing NAD+ levels in cancer-associated fibroblasts	10
Extracellular nicotinamide phosphoribosyltransferase visfatin activates JAK2-STAT3 pathway in cancer-associated fibroblasts to promote colorectal cancer metastasis	9
Whole-genome sequencing revealed different demographic histories among the Korean endemic hill pigeon (Columba rupestris), rock pigeon (Columba livia var. domestica) and oriental turtle dove (Streptop	9
Discovery of high-expressing lncRNA-derived sORFs as potential tumor-associated antigens in hepatocellular carcinoma	9
Knockdown of growth differentiation factor-15 inhibited nonsmall cell lung cancer through inactivating PTEN/PI3K/AKT signaling pathway	9
MicroRNA-9 inhibits proliferation and progression in retinoblastoma cells by targeting PTEN	9
Lactucin induces apoptosis through reactive oxygen species-mediated BCL-2 and CFLARL downregulation in Caki-1 cells	9
Genetic diversity and genetic differentiation of Megalobrama populations inferred by mitochondrial markers	9
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells	9
Identification of novel candidate genes implicated in odontogenic potential in the developing mouse tooth germ using transcriptome analysis	9
Prospects and challenges of epigenomics in crop improvement	9
Towards fine-scale population stratification modeling based on kernel principal component analysis and random forest	9
Feature selection for effective prediction of SARS-COV-2 using machine learning	9
Characterization of the complete mitogenome of the endangered freshwater fish Gobiobotia naktongensis from the Geum River in South Korea: evidence of stream connection with the Paleo-Huanghe	9
Genome-wide DNA methylation analysis in schizophrenia with tardive dyskinesia: a preliminary study	9
Whole exome sequencing of 80 cases of sporadic mitral valve prolapse reveals novel disease-associated genes and variants in a Southern Chinese population	8
Transcriptome analysis of response strategy in Hemerocallis fulva under drought stress	8
The impact of histone lactylation on the tumor microenvironment and metabolic pathways and its potential in cancer therapy	8
c-Jun N-terminal kinase 1 (JNK1) phosphorylates OTX2 transcription factor that regulates early retinal development	8
Kernel-based hierarchical structural component models for pathway analysis on survival phenotype	8
CALM1 rs3179089 polymorphism might contribute to coronary artery disease susceptibility in Chinese male: a case–control study	8
Description of the whole mitochondrial genome of Bhatia longiradiata (Hemiptera, Cicadellidae, Deltocephalinae: Drabescini) and phylogenetic relationship	8
ADP-glucose pyrophosphorylase gene family in soybean and implications in drought stress tolerance	8
RNA sequencing reveals lncRNA-mediated non-mendelian inheritance of feather growth change in chickens	8
Genome-wide locus-specific DNA methylation repatterning may facilitate rapid evolution of mercury resistance in rice	8
Complete genome sequence of the Pogostemon cablin bacterial wilt pathogen Ralstonia solanacearum strain SY1	8
Digital insights into Pseudomonas aeruginosa PBH03: in-silico analysis for genomic toolbox and unraveling cues for heavy metal bioremediation	8
Identification of DNA methylation and genetic alteration simultaneously from a single blood biopsy	8
High-throughput data on circular RNA reveal novel insights into chronic glomerulonephritis	8
In silico identification and expression analysis of superoxide dismutases in Tenebrio molitor	8
Analysis of evolutionary and genetic patterns in structural genes of primate lentiviruses	8
Comparative analysis of cancer gene mutations using targeted sequencing in matched primary and recurrent gastric cancers after chemotherapy	7
Comparison of unique Dong Tao chickens from Vietnam and Thailand: genetic background and differences for resource management	7
METTL3 m6A-dependently promotes miR-21-5p maturation to accelerate choriocarcinoma progression via the HIF1AN-induced inactivation of the HIF1A/VEGF pathway	7
Tumor suppressive effect of scavenger receptor class A member 5 overexpression in colorectal cancer by regulating PI3K/AKT/mTOR pathway	7
Correction: Suppression of synuclein gamma inhibits the movability of endometrial carcinoma cells by PI3K/AKT/ERK signaling pathway	7
VDR mediated HSD3B1 to regulate lipid metabolism and promoted testosterone synthesis in mouse Leydig cells	7
Getting the chronological age out of DNA: using insights of age-dependent DNA methylation for forensic DNA applications	7
miR-582-5p inhibits migration and chemo-resistant capabilities of colorectal cancer cells by targeting TNKS2	7
Identification of novel CDH23 heterozygous variants causing autosomal recessive nonsyndromic hearing loss	7
Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma	7
Genetic association study identifies genetic variants for non-alcoholic fatty liver without comorbidities in the Korean population	7
Weighted gene co-expression network analysis and identification of ginsenoside biosynthesis candidate genes for ginseng adventitious roots under MeJA treatment	7
miR-214-3p inhibits LPS-induced macrophage inflammation and attenuates the progression of dry eye syndrome by regulating ferroptosis in cells	6
Four mutations identified in Chinese families with autosomal dominant congenital cataracts by next-generation sequencing	6
Clinical and genetic analyses in syndromic intellectual disability with primary microcephaly reveal biallelic and de novo variants in patients with parental consanguinity	6
A novel role of the cotton calcium sensor CBL3 was involved in Verticillium wilt resistance in cotton	6
Human umbilical cord mesenchymal stem cells overexpressing RUNX1 promote tendon-bone healing by inhibiting osteolysis, enhancing osteogenesis and promoting angiogenesis	6
Ectopic expression of AtMYB115 and AtMYB118 induces green tissue formation in non-green organs of Arabidopsis thaliana	6
Comprehensive assessment of the significance of cellular senescence-associated genes in neuroblastoma	6

Neferine increases sensitivities to multiple anticancer drugs via downregulation of Bcl-2 expression in renal cancer cells	6
Gene expression profile in ulcerative colitis patients: FOXO4, ALDOB, SLC26A3, SOD2 genes as potential biomarkers	6
Transcriptomic analysis of neutrophil apoptosis induced by diffuse large B-cell lymphoma unveils a potential role in neutropenia	6
Genome-wide analysis of the potato GRF gene family and their expression profiles in response to hormone and Ralstonia solanacearum infection	6
Genome-wide identification of the valine-glutamine motif containing gene family and the role of VQ25-1 in pollen germination in Brassica oleracea	6
Identification a novel de novo RUNX2 frameshift mutation associated with cleidocranial dysplasia	6
PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation	6
Differential expression and functional analysis of circRNA in the ovaries of Yili geese at different egg-laying stages	6
LncRNA KTN1-AS1 facilitates esophageal squamous cell carcinoma progression via miR-885-5p/STRN3 axis	6
Genomic analyses of intricate interaction of TE-lncRNA overlapping genes with miRNAs in human diseases	6
Identification of a novel prognostic signature composed of 3 cuproptosis-related transcription factors in colon adenocarcinoma	6
Role of tyrosine autophosphorylation and methionine residues in BRI1 function in Arabidopsis thaliana	6
Characteristics of insulin resistance in Korean adults from the perspective of circadian and metabolic sensing genes	6
Genome-wide identification of drought-responsive microRNAs and their target genes in Chinese jujube by deep sequencing	6
Comparative analysis of human facial skin microbiome between topical sites compared to entire face	6
RPTOR methylation in the peripheral blood and breast cancer in the Chinese population	6
Single-cell transcriptomic analysis reveals transcriptional and cell subpopulation differences between human and pig immune cells	6
Identification of Saccharum CaM gene family and function characterization of ScCaM1 during cold and oxidant exposure in Pichia pastoris	6
A novel pathogenic deletion in ISPD causes Walker-Warburg syndrome in a Chinese family	5
Comparative analysis of VMT genes/proteins in selected plant species with emphasis on bread wheat (Triticum aestivum L.)	5
Centromere protein N promotes lung adenocarcinoma progression by activating PI3K/AKT signaling pathway	5
Transcriptional upregulation of multiple earthworm chitinase genes following bacterial challenge suggests their implications in innate immunity	5
Omi inhibition ameliorates neuron apoptosis and neurological deficit after subarachnoid hemorrhage in rats	5
Transcriptional induction of TGF-β1 and endothelial-to-mesenchymal transition cell markers in human umbilical vein endothelial cells by Ebola virus infection	5
The coefficients of inbreeding revealed by ROH study among inbred individuals belonging to each type of the first cousin marriage: A preliminary report from North India	5
Using weighted gene co-expression network analysis (WGCNA) to identify the hub genes related to hypoxic adaptation in yak (Bos grunniens)	5
Perillic acid disrupts the specification of germ layers by upregulating the FGF/MAPK pathway	5
Full-length transcriptome combined with RNA sequence analysis of Fraxinus chinensis	5
Overexpression of TRIM44 mediates the NF-κB pathway to promote the progression of ovarian cancer	5
Phylogenetic relationships between three Korean pit viper Gloydius (Serpentes: Crotalinae) species using mitochondrial DNA genes	5
Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer	5
A novel study on CXXC5: unraveling its regulatory mechanisms in hematopoietic stem cell biology through proteomics and gene editing	5
P14.5 functions to inhibit cell migration and can be used as a prognostic marker in hepatocellular carcinoma	5
Optimizing Bangkaew dog breed identification using DNA technology	5
Berberine protects against palmitate induced beta cell injury via promoting mitophagy	5
Characterization and comparative analysis of the complete organelle genomes of three red macroalgae species (Neoporphyra dentata, Neoporphyra seriata, and Neopyropia yezoensis) and development of mole	5
Genome-wide DNA methylation profiling in differentiating Crohn’s disease from intestinal tuberculosis	5
Current issues in forensic genetics	5
Estimating the age of single nucleotide polymorphic sites in humans	5
Coffin-Siris syndrome in two chinese patients with novel pathogenic variants of ARID1A and SMARCA4	5
Establishment of a novel myocarditis mouse model based on cyclosporine A	5
Epigenome editing: targeted manipulation of epigenetic modifications in plants	5
A novel approach of kinship determination based on the physical length of genetically shared regions of chromosomes	5
Salivary amylase gene (AMY1) copy number variation has only a minor correlation with body composition in Chinese adults	5
Transcriptome analysis reveals genes connected to temperature adaptation in juvenile antarctic krill Euphausia superba	5
Baicalin attenuates adriamycin-induced nephrotic syndrome by regulating fibrosis procession and inflammatory reaction	5
Association of DAZL polymorphisms and DAZ deletion with male infertility: a systematic review and meta-analysis	4
Inactivation of epithelial sodium ion channel molecules serves as effective diagnostic biomarkers in clear cell renal cell carcinoma	4
A combination of upstream alleles involved in rice heading hastens natural long-day responses	4
Molecular cloning, expression analysis, and functional characterization of Intelectin-1 from Chinese giant salamanders (Andrias davidianus)	4
Transcriptomic profiling of the cold stress and recovery responsiveness of two contrasting Guizhou HE rice genotypes	4
Identification of Feronia-interacting proteins in Arabidopsis thaliana	4
Uncovering microsatellite markers associated with agronomic traits of South Sudan landrace maize	4
A comparative investigation of single nucleotide variant calling for a personal non-Caucasian sequencing sample	4
A20 ameliorates disc degeneration by suppressing mTOR/BNIP3 axis-mediated mitophagy	4
CKAP4 is a potential therapeutic target to overcome resistance to EGFR-TKIs in lung adenocarcinoma	4
E3 ligase MIB1 regulates STAT1/P21 signaling via regulation of FGFR1 in colorectal cancer	4
Four novel mutations in the androgen receptor gene from Vietnamese patients with androgen insensitivity syndrome	4
Genome-wide identification and expression profiling of the Wnt gene family in three abalone species	4
Tripartite Motif Containing 3 inhibits the aggressive behaviors of papillary thyroid carcinoma and indicates lower recurrence risk	4
Cryptic diversity and population genetic structure of the mantis shrimp Oratosquilla oratoria in South Korea	4
Mmu_circ_0000271 regulated the growth of ox-LDL-stimulated mouse vascular smooth muscle cells via sponging miR-5123	4
Prognostic value of Nrf2/HO-1 expression and its correlation with occurrence in esophageal squamous cell carcinoma	4
Deubiquitinating enzyme Josephin-2 stabilizes PHGDH to promote a cancer stem cell phenotype in hepatocellular carcinoma	4
Disclosing the hidden nucleotide sequences: a journey into DNA barcoding of raptor species in public repositories	4
Complete mitochondrial genome of the Chinese Callipogon (Eoxenus) relictus (Cerambycidae: Prioninae) with phylogenetic analyses	4
Complete chloroplast genomes of three Polygala species and indel marker development for identification of authentic polygalae radix (Polygala tenuifolia)	4
MicroRNA-183 accelerates the proliferation of hepatocyte during liver regeneration through targeting programmed cell death protein 6	4
Rex: R-linked EXcel add-in for statistical analysis of medical and bioinformatics data	4
A class I histone deacetylase HDA-2 is essential for embryonic development and size regulation of fertilized eggs in Caenorhabditis elegans	4
Epigenetic regulation of HERVs: Implications for cancer immunotherapy	4
Helicobacter pylori infection induces gastric cancer cell malignancy by targeting HOXA-AS2/miR-509-3p/MMD2 axis	4
Pitfalls of whole exome sequencing in undefined clinical conditions with a suspected genetic etiology	4
Role of Brassica rapa SWEET genes in the defense response to Plasmodiophora brassicae	4
Population genetics reveals new introgression in the nucleus herd of min pigs	4
Genetic variation of seed oil characteristics in native Korean germplasm of Perilla crop (Perilla frutescens L.) using SSR markers	4
LncRNA-GAS5/miR-382-3p axis inhibits pulmonary artery remodeling and promotes autophagy in chronic thromboembolic pulmonary hypertension	4
Genetic diversity and structure of Persicaria amphibia (Polygonaceae) in South Korea using genotyping by sequencing	4
Identification and characterization of Acinetobacter nosocomialis BfmRS, two-component regulatory system, essential for biofilm development	4