OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Oral Microbiology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The effect of different sweeteners on the oral microbiome: a randomized clinical exploratory pilot study	194
Porphyromonas gingivalis -OMVs promote the epithelial-mesenchymal transition of oral squamous cell carcinoma by inhibiting ferroptosis through the NF-κB pathway	105
Novel biomarker identification for oral squamous cell carcinoma development in nonsmoker, nondrinker, and nonchewer patients using third-generation sequencing of oral microbiome	90
Fusobacterium nucleatum as an oral bacteria promotes the carcinogenesis of laryngeal cancer via upregulating YWHAZ	79
Role of immunostimulatory deoxycytidylate-phosphate-deoxyguanylate (CpG) motifs in oral bacteria associated with oral diseases	53
Bidirectional effects of neutrophils on Streptococcus oralis biofilms in vitro	46
Inhibitory effect of helium cold atmospheric plasma on cariogenic biofilms	43
Locational effects on oral microbiota among long-term care patients	42
Guideline for the analysis of the microbial communities of the human upper airways	38
Novel approaches on root canal disinfection methods against E. faecalis	37
Altered oral microbiome composition in mental disorders: a systematic review and meta-analysis	35
Maturation of the oral microbiota during primary teeth eruption: a longitudinal, preliminary study	35
Interaction between microorganisms and dental material surfaces: general concepts and research progress	26
Nitrate reduction by salivary bacteria, glucose metabolism, and lifestyle	26
N -acyl homoserine lactones lactonase est816 suppresses biofilm formation and periodontitis in rats mediated by Aggregatibacter actinomycetemcomitans	25
The association between the oral microbiome and hypertension: a systematic review	24
The importance of biofilm contamination control for dental unit waterlines: a multicenter assessment of the microbiota diversity of biofilm in dental unit waterlines	22
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis	22
Impact of HbA1c control and type 2 diabetes mellitus exposure on the oral microbiome profile in the elderly population	22
Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain	22
Deficiency of dltD contributes to increased autolysis in Streptococcus mutans	21
Detection of Epstein-Barr virus infection in primary junctional epithelial cell cultures	21
Distinct oral DNA viral signatures in rheumatoid arthritis: a Pilot study	21
Cytokine release and NLRP3 inflammasome activation induced by low-abundance oral bacterial biofilms	21
Efficacy of gigantol, a bibenzyl compound, against Porphyromonas gingivalis	21

Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria	20
Characterization of the unique oral microbiome of children harboring Helicobacter pylori in the oral cavity	20
Inflammatory response of gut, spleen, and liver in mice induced by orally administeredPorphyromonas gingivalis	20
DNA virus tropism in healthy dental pulp: an in-situ reservoir site for torque teno virus and parvovirus B19	19
Longitudinal profiles of oral microbiome in patients with nasopharyngeal carcinoma and their prognostic implications	17
Ultrasmall epibiont Nanosynbacter lyticus strain TM7x and host bacteria transcriptional activity after initial host parasitism	17
Unveiling the complexity of early childhood caries: Candida albicans and Streptococcus mutans cooperative strategies in carbohydrate metab	17
Effective disinfecting of negative pressure pipelines of DCUs reduces the risk of cross infection in dental care	16
Patients with periodontitis exhibit persistent dysbiosis of the gut microbiota and distinct serum metabolome	16
Newly identified pathogens in periodontitis: evidence from an association and an elimination study	16
Is systemic inflammation a missing link between oral microbiome and oral squamous cell carcinoma? Results from multi-omics integration analyses	16
Role of Enterococcus faecalis in refractory apical periodontitis: from pathogenicity to host cell response	16
Effect of implant abutment surface treatments on bacterial biofilm composition and structure	15
Feasibility of oral microbiome profiles associated with oral squamous cell carcinoma	15
Methanobrevibacter oralis : a comprehensive review	15
Oxidative stress response: a critical factor affecting the ecological competitiveness of Streptococcus mutans	15
Dual transcriptome of Streptococcus mutans and Candida albicans interplay in biofilms	14
Correlation between oral microbiota and dry socket at different time periods on tooth extraction	14
Arginine-specific gingipains (RgpA/RgpB) knockdown modulates neutrophil machinery	14
Antagonistic interaction between two key endodontic pathogens Enterococcus faecalis and Fusobacterium nucleatum	14
The effects of nitrate on the oral microbiome: a systematic review investigating prebiotic potential	14
Functional characteristics of membrane vesicles produced by Streptococcus mitis	13
Effect of Helicobacter pylori on enamel and dentin development – an in vitro study in mice	13
The oral microbiome in alcohol use disorder: a longitudinal analysis during inpatient treatment	13
Dysbiosis of the oropharyngeal microbiota in COVID-19: distinct profiles in patients with severe respiratory symptoms	13
Porphyromonas gingivalis-Helicobacter pylori co-incubation enhances Porphyromonas gingivalis virulence and increases migration of infected human oral keratinocytes	13
Evaluation of a Burkholderia ambifaria strain from plants as a novel promising probiotic in dental caries management	13
Enhanced dominance of nitrate-reducing bacteria using a combination of nitrate and erythritol in in vitro cultured oral biofilm	13
Microbiome variability and role of Candida albicans in site-specific dental plaques in orthodontic adolescent patients with white spot lesions	12
Genetic characterization of glyoxalase pathway in oral streptococci and its contribution to interbacterial competition	12
High prevalence of antibiotic resistance of Streptococcus species in saliva from non-hospitalized adults – a pilot study	12
Characterization of MreCD in Streptococcus mutans	12
A genomic sequence of the type II-A clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated system in Mycoplasma salivarium strain ATCC 29803	12
Comparison of the performance of MiSeq and NovaSeq in oral microbiome study	12
Profiles of oral microbiome associated with nasogastric tube feeding	12
Screening of heat-killed lactic acid bacteria based on inhibitory activity against oral bacteria and effects of oral administration of heat-killed Ligilactobacillus salivarius	11
Development of antibacterial composite resin containing chitosan/fluoride microparticles as pit and fissure sealant to prevent caries	11
Understanding the bacterial compositional network associations between oral and gut microbiome within healthy Koreans	11
Phenotypic and genotypic characterization of Candida species from the oral cavity of healthy individuals in Lublin province, Poland	11
Altered composition of the oral microbiome in integrin beta 6-deficient mouse	11
Role of ferroptosis in Porphyromonas gingivalis- induced impairment of epithelial junction	11
Microbial manipulators: Fusobacterium nucleatum modulates the tumor immune microenvironment in colorectal cancer	11
Coaggregation of oral pathogens by postbiotic lactobacilli	11
RE: colonization of bacterial and viral respiratory pathogens among healthcare workers in China during COVID-19 pandemic	11
The oral microbiome and oral and upper gastrointestinal diseases	10
Mapping bacterial diversity and metabolic functionality of the human respiratory tract microbiome	10
Multiomics analysis reveals the genetic and metabolic characteristics associated with the low prevalence of dental caries	10
Potential oral probiotic Lactobacillus pentosus MJM60383 inhibits Streptococcus mutans biofilm formation by inhibiting sucrose decomposition	10
Comprehensive analysis of the oral microbiota and metabolome change in patients of burning mouth syndrome with psychiatric symptoms	9
MALDI-TOF mass spectrometry of saliva samples as a prognostic tool for COVID-19	9

Targeting cariogenic pathogens and promoting competitiveness of commensal bacteria with a novel pH-responsive antimicrobial peptide	9
The potential regulatory role of mannose phosphotransferase system EII in alkaline resistance of Enterococcus faecalis	9
Impact of increased Porphyromonas gingivalis peptidylarginine deiminase (PPAD) T2 variant allele on oral microbiota composition and severity of chronic periodontitis	9
Porphyromonas gingivalis lipopolysaccharide induced RIPK3/MLKL-mediated necroptosis of oral epithelial cells and the further regulation in macrophage activation	9
Cross-comparison of microbiota in the oropharynx, hypopharyngeal squamous cell carcinoma and their adjacent tissues through quantitative microbiome profiling	9
Correction	9
The metagenome and metabolome signatures of dental biofilms associated with severe dental fluorosis	9
Microbiome profiles of non-responding and responding paired periodontitis sites within the same participants following non-surgical treatment	9
Preventive effects of Weissella cibaria CMU on the progression of periodontitis in a rat model	8
Correlation of tongue coating thickness with microinflammatory state and oral microbiome in maintenance hemodialysis patients	8
Oral microbiomes of patients with infective endocarditis (IE): a comparative pilot study of IE patients, patients at risk for IE and healthy controls	8
A review and new perspective on oral bacteriophages: manifestations in the ecology of oral diseases	8
Silica nanoparticles containing nano-silver and chlorhexidine to suppress Porphyromonas gingivalis biofilm and modulate multispecies biofilms toward healthy tendency	8
Functional divergence of MdpS and MdpS2 reveals mucin-targeting strategies in Streptococcus oralis	8
Quantification of torque teno virus (TTV) DNA in saliva and plasma samples in patients at short time before and after kidney transplantation	8
Nicotinamide could reduce growth and cariogenic virulence of Streptococcus mutans	8
Secretome analysis and virulence assessment in Abiotrophia defectiva	8
Structural and antigenic characterization of a novel genotype of Mfa1 fimbriae in Porphyromonas gingivalis	7
Smoking, tooth loss and oral hygiene practices have significant and site-specific impacts on the microbiome of oral mucosal surfaces: a cross-sectional study	7
Subgingival microbiome at different levels of cognition	7
Correlation of periodontitis with hepatic and intestinal inflammation and glycemic control, and effects of bioconverted Artemisia herba-alba by Lactiplant	7
Oral and gut microbial profiling in periodontitis and Parkinson’s disease	7
Exploring the biomedical potential of a novel modified glass ionomer cement against the pandrug-resistant oral pathogen Candida albicans SYN-01	7
Streptococcus cristatus reduces cariogenicity of saliva-derived microcosms under pH-dependent conditions	7
Postmenopausal osteoporosis increases periodontal inflammation and the pathogenicity of the oral microbiota in a rat model	7
CKIP-1 mediates P. gingivalis -suppressed osteogenic/cementogenic differentiation of periodontal ligament cells partially via p38 signaling pathway	7
Anti-biofilm studies of synthetic imidazolium salts on dental biofilm in vitro	7
Water-insoluble exopolysaccharide synthesized by glucosyltransferases mediates the antibacterial activity of ClyR against Streptococcus mutans <	7
Exploration of the interplay between spatially distinct microbial habitats through comparative analysis	7
Oral bacteriophages and their potential as adjunctive treatments for periodontitis: a narrative review	6
Inhibition of Streptococcus mutans adhesion and biofilm formation with small-molecule inhibitors of sortase A from Juniperus chinensis	6
Alterations of oral microbiota are associated with the development and severity of acute pancreatitis	6
Regulatory mechanisms of exopolysaccharide synthesis and biofilm formation in Streptococcus mutans	6
Association of nine pathobionts with periodontitis in four South American and European countries	6
P. gingivalis alters lung microbiota and aggravates disease severity of COPD rats by up-regulating Hsp90α/MLKL	6
Dysbiotic human oral microbiota alters systemic metabolism via modulation of gut microbiota in germ-free mice	6
Maintaining oral health for a hundred years and more? - An analysis of microbial and salivary factors in a cohort of centenarians	5
Ecological competition in the oral mycobiome of Hispanic adults living in Puerto Rico associates with periodontitis	5
Supragingival microbiome variations and the influence of Candida albicans in adolescent orthodontic patients with gingivitis	5
Current concepts in the pathogenesis of periodontitis: from symbiosis to dysbiosis	5
The interplay between oral microbiota, gut microbiota and systematic diseases	5
Impact of different oral treatments on the composition of the supragingival plaque microbiome	5
Transposon mutagenesis in oral streptococcus	5
Assessing the drug resistance profiles of oral probiotic lozenges	5
Effects of honokiol combined with resveratrol on bacteria responsible for oral malodor and their biofilm	5
Streptococcus mutans-associated bacteria in dental plaque of severe early childhood caries	5
Viral DNA in submandibular gland tissue with an inflammatory disorder	5
Human periodontitis-associated salivary microbiome affects the immune response of diabetic mice	5
A tightly controlled gene induction system that contributes to the study of lethal gene function in Streptococcus mutans	5
Dental caries and their microbiomes in children: what do we do now?	5
Characterization of the salivary microbiome of adults with inflammatory bowel disease	5
The comparative effect of propolis and chlorhexidine mouthwash on oral nitrite-producing bacteria and blood pressure regulation	5
An oral microbiota-based deep neural network model for risk stratification and prognosis prediction in gastric cancer	4
Longitudinal analysis of oral microbiome changes during the neonatal period in full-term and preterm newborns	4
Glycosylation of oral bacteria in modulating adhesion and biofilm formation	4
Meta-omics reveals subgingival plaque reconstruction dynamics	4
Functional and taxonomic dysbiosis of the supragingival plaque metagenome in Behçet’s disease	4
First water safety plan approach applied to a Dental Clinic complex: identification of new risk factors associated with Legionella and P. aeruginosa	4
Global proteomics of fibroblast cells treated with bacterial cyclic dinucleotides, c-di-GMP and c-di-AMP	4
Sub-lethal concentrations of chlorhexidine inhibit Candida albicans growth by disrupting ROS and metal ion homeostasis	4
Effect of mobile app-based oral hygiene instructions on clinical parameters, oral bacterial diversity, and composition of subgingival microbiota in periodontitis patients	4
VBNC, previously unrecognized in the life cycle of Porphyromonas gingivalis?	4
Sepsis and septic shock caused by Porphyromonas gingivalis : a case report	4
Arginine-induced metabolomic perturbation in Streptococcus mutans	4
Breastfeeding patterns and total volume of human milk consumed influence the development of the infant oral microbiome	4