OOIR: Observatory of International Research

Papers

(The H4-Index of Computational and Structural Biotechnology Journal is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Optimized quantitative bacterial two-hybrid (qB2H) for protein-protein interaction assessment	186
Ecological and functional stratification of the stool microbiome predicts response to immune checkpoint inhibitors across cancer types	182
Predicting cellular adaptation proteins dependent on eIF2α regulation under stress conditions: Physiological and pathophysiological implications in neuronal function	152
Corrigendum to “Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and	137
Towards predicting implant-induced fibrosis: A standardized network model of macrophage-fibroblast interactions	135
Phylogenetic tree-based amino acid sequence generation for proteomics data analysis of unknown species	124
Ranking pre-trained speech embeddings in Parkinson's disease detection: Does Wav2Vec 2.0 outperform its 1.0 version across speech modes and languages?	103
Gut microbiome enterotypes and temporal variations during a six-month inulin-supplemented weight loss randomized controlled trial in Thai children with obesity	102
macpie: Scalable workflow for high-throughput transcriptomic profiling	97
Radiomic clustering using graph network techniques coupled with unbalanced optimal transport	80
CKATool: A clinical kinematic analysis toolbox for upper limb rehabilitation	78
Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants	73
DiabetesOmic: A comprehensive multi-omics diabetes database	70
Evolution is in the details: Regulatory differences in modern human and Neanderthal	70
Structural elucidation of four fungal hydrophobins belonging to classes I and II: Results from Alphafold and accelerated molecular dynamics simulations	69
EthnoHERBS: Harnessing traditional herbal knowledge for biodiversity conservation and innovative health solutions	68
Computational fluid dynamics modeling and simulation of nanoparticle-tumor interaction: Systematic literature review	68
Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach	66
MMRT: MultiMut Recursive Tree for predicting functional effects of high-order protein variants from low-order variants	62
A miRNA signature linked to high lipoprotein (a) and coronary calcification in familial hypercholesterolaemia	59
Comprehensive exploration of JQ1 and GSK2801 targets in breast cancer using network pharmacology and molecular modeling approaches	56
VTAM: A robust pipeline for validating metabarcoding data using controls	56
Discovery of a novel marine Bacteroidetes with a rich repertoire of carbohydrate-active enzymes	54
In silico and in vitro approaches allow the identification of the Prosystemin molecular network	54
Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis	53

Pseudotimecascade Visualizes Gene Expression Cascade in Pseudotime Analysis	50
CRUSADE project: Recycling technologies for ELV components to create a sustainable source of market grade materials for EU applications	49
Automated machine learning in nanotoxicity assessment: A comparative study of predictive model performance	48
The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins	48
Consistencies and contradictions in different polymer models of chromatin architecture	48
From latent dynamics to data geometry: Nonlinear diffusion modelling for protein structures	48
Computation-aided studies related to the induction of specialized metabolite biosynthesis in microbial co-cultures: An introductory overview	48
A novel exosome-derived prognostic signature and risk stratification for breast cancer based on multi-omics and systematic biological heterogeneity	47
The balance between photosynthesis and respiration explains the niche differentiation between Crocosphaera and Cyanothece	44
A drug repurposing method based on inhibition effect on gene regulatory network	43
Identification and biophysical characterization of epitope atlas of Porcine Reproductive and Respiratory Syndrome Virus	43
Cell segmentation and representation with shape priors	43
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel	43
Corrigendum to “Cryo-EM reveals architectural diversity in active rotavirus particles” [Comput. Struct. Biotechnol. J. 17 (2019) 1178–1183]	42
Entropy-extreme model for predicting the development of cyber epidemics at early stages	42
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data	42
Agreement and disagreement in pediatric functional neurological symptom disorders: Comparing patient reported outcome measures (PROMs) and clinician assessments	42
cPEPmatch Webserver: A comprehensive tool and database to aid rational design of cyclic peptides for drug discovery	42
Predictive dynamic control accurately maps the design space for 2,3-butanediol production	42