OOIR: Observatory of International Research

Papers

(The H4-Index of Computational and Structural Biotechnology Journal is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Agreement and disagreement in pediatric functional neurological symptom disorders: Comparing patient reported outcome measures (PROMs) and clinician assessments	288
Corrigendum to “Cryo-EM reveals architectural diversity in active rotavirus particles” [Comput. Struct. Biotechnol. J. 17 (2019) 1178–1183]	268
In silico and in vitro approaches allow the identification of the Prosystemin molecular network	189
The balance between photosynthesis and respiration explains the niche differentiation between Crocosphaera and Cyanothece	164
Evidence of a SARS-CoV-2 double Spike mutation D614G/S939F potentially affecting immune response of infected subjects	161
NGS allele counts versus called genotypes for testing genetic association	159
dsCellNet: A new computational tool to infer cell–cell communication networks in the developing and aging brain	148
Network-based prioritization of cancer biomarkers by phenotype-driven module detection and ranking	131
An integrated protein structure fitness scoring approach for identifying native-like model structures	119
Biomarker discovery process at binomial decision point (2BDP): Analytical pipeline to construct biomarker panel	119
Cell segmentation and representation with shape priors	116
Comprehensive exploration of JQ1 and GSK2801 targets in breast cancer using network pharmacology and molecular modeling approaches	100
Optimizing the Illumina COVIDSeq laboratorial and bioinformatics pipeline on thousands of samples for SARS-CoV-2 Variants of Concern tracking	96
VTAM: A robust pipeline for validating metabarcoding data using controls	95
Prediction of protein-ligand binding affinity with deep learning	93
Identification and biophysical characterization of epitope atlas of Porcine Reproductive and Respiratory Syndrome Virus	92
Entropy-extreme model for predicting the development of cyber epidemics at early stages	90
MUG: A mutation overview of GPCR subfamily A17 receptors	83
Artificial intelligence predictive system of individual survival rate for lung adenocarcinoma	82
A novel exosome-derived prognostic signature and risk stratification for breast cancer based on multi-omics and systematic biological heterogeneity	79
Streptomyces coelicolor macrodomain hydrolase SCO6735 cleaves thymidine-linked ADP-ribosylation of DNA	75
Predictive dynamic control accurately maps the design space for 2,3-butanediol production	72
Computation-aided studies related to the induction of specialized metabolite biosynthesis in microbial co-cultures: An introductory overview	71
Free energy landscape of the PI3Kα C-terminal activation	70
Discovery of a novel marine Bacteroidetes with a rich repertoire of carbohydrate-active enzymes	69

Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis	68
The second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14–3-3 proteins	67
Identification of (Z)-2-benzylidene-dihydroimidazothiazolone derivatives as tyrosinase inhibitors: Anti-melanogenic effects and in silico studies	66
CKATool: A clinical kinematic analysis toolbox for upper limb rehabilitation	65
Advanced biokinetic and hydrodynamic modelling to support and optimize the design of full-scale high rate algal ponds	64
Nextcast: A software suite to analyse and model toxicogenomics data	64
Multi-omics landscape and clinical significance of a SMAD4-driven immune signature: Implications for risk stratification and frontline therapies in pancreatic cancer	63
Using molecular dynamics simulations to interrogate T cell receptor non-equilibrium kinetics	62
Structural elucidation of four fungal hydrophobins belonging to classes I and II: Results from Alphafold and accelerated molecular dynamics simulations	61
cPEPmatch Webserver: A comprehensive tool and database to aid rational design of cyclic peptides for drug discovery	60
The influence of HIV sense and antisense transcripts on stochastic HIV transcription and reactivation	60
UPIMAPI, reCOGnizer and KEGGCharter: Bioinformatics tools for functional annotation and visualization of (meta)-omics datasets	58
What remains from living cells in bacterial lysate-based cell-free systems	58
Phylogenetic tree-based amino acid sequence generation for proteomics data analysis of unknown species	57
Towards predicting implant-induced fibrosis: A standardized network model of macrophage-fibroblast interactions	57
Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants	56
Evolution is in the details: Regulatory differences in modern human and Neanderthal	55
A miRNA signature linked to high lipoprotein (a) and coronary calcification in familial hypercholesterolaemia	54
Deep5mC: Predicting 5-methylcytosine (5mC) methylation status using a deep learning transformer approach	54
MMRT: MultiMut Recursive Tree for predicting functional effects of high-order protein variants from low-order variants	54
macpie: Scalable workflow for high-throughput transcriptomic profiling	53
DiabetesOmic: A comprehensive multi-omics diabetes database	52
Gut microbiome enterotypes and temporal variations during a six-month inulin-supplemented weight loss randomized controlled trial in Thai children with obesity	52
Radiomic clustering using graph network techniques coupled with unbalanced optimal transport	52
Corrigendum to “Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and reduces piglet diarrhea” [Comput Struct Biotech	51
DIPAN: Detecting personalized intronic polyadenylation derived neoantigens from RNA sequencing data	51