OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 50. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	697
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	240
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	208
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	157
	155
	141
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	134
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	134
Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals	129
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	122
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	112
Faecal zonulin, calprotectin and the infant microbiome in early life	104
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	99
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	99
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	98
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	96
Glucosamine regulates macrophage function in heart failure	95
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	91
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	86
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	84
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	81
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	80
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	77
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	76
Mitochondrial and immune response dysregulation in melanoma recurrence	75

Seize the engine: Emerging cell cycle targets in breast cancer	75
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	74
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	73
Sendotypes predict worsening renal function in chronic kidney disease patients	72
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	65
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	64
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	63
Molecular and physical technologies for monitoring fluid and electrolyte imbalance: A focus on cancer population	60
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	59
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	59
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	58
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	55
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	54
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	54
Lipids and genes: Regulatory roles of lipids in RNA expression	54
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	53
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	52
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	52
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	52
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	52
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	51
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	51
	50
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts	50
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis	50