OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	828
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	297
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	203
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	168
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	147
Seize the engine: Emerging cell cycle targets in breast cancer	145
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	136
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	126
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	116
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	111
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	111
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	107
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	105
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	102
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	97
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	97
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	95
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	89
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	82
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	81
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	80
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	80
Glucosamine regulates macrophage function in heart failure	73
Sendotypes predict worsening renal function in chronic kidney disease patients	71
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	70

Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	67
Faecal zonulin, calprotectin and the infant microbiome in early life	67
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	66
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	65
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	65
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	65
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	62
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	61
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	61
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	60
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	59
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	57
Mitochondrial and immune response dysregulation in melanoma recurrence	56
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	56
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	55
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	55
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	54
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	54
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	54
	54
	53
Lipids and genes: Regulatory roles of lipids in RNA expression	53
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	52
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	52
Nanopore sequencing with T2T‐CHM13 for accurate detection and preventing the transmission of structural rearrangements in highly repetitive heterochromatin regions in human embryos	51
	51
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib	51