OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	386
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	321
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	149
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	147
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	137
	135
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	126
	125
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	115
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	103
Sendotypes predict worsening renal function in chronic kidney disease patients	98
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	94
Mitochondrial and immune response dysregulation in melanoma recurrence	94
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	94
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	92
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	92
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	91
Faecal zonulin, calprotectin and the infant microbiome in early life	90
Regulatory mechanism of O‐linked N‐acetylglucosamine protein modification on autophagy in cancer	87
The biological burden of conflict across populations worldwide	83
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	79
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	76
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	74
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	73
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	72

The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	72
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	70
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	70
Illuminating the genomic frontier of invasive non‐typhoidal Salmonella infections	68
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	67
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	64
Lipids and genes: Regulatory roles of lipids in RNA expression	63
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	63
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	63
Seize the engine: Emerging cell cycle targets in breast cancer	60
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	60
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	59
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	58
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	58
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	57
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	57
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	56
A droplet that releases stress: Drop‐printing for conformal bioelectronics at neural and soft‐tissue interfaces	55
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	55
Macrophage Cluster of Differentiation 163 promotes post‐infarction cardiac repair and preserves left ventricular function via osteopontin	54
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	53
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	53
Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	53
Targeting lysine methyltransferase 2C deficiency: New frontiers in breast cancer therapy and prognosis	52
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	49
Suicide among patients with cancer: a call to action for researchers and clinical caregivers	49
	49
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	49
NDP‐β‐d‐manno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms	49