OOIR: Observatory of International Research

Papers

(The H4-Index of Clinical and Translational Medicine is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
	966
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	332
The deubiquitinase OTUD3 plays a neuroprotective role by reducing ferroptosis induced by cerebral ischaemia reperfusion via stabilizing PLK1 via deubiquitination	254
Targeting receptor for activated C kinase 1 with a small molecule induces mitotic catastrophe and suppresses lipid metabolic reprogramming in hepatocellular carcinoma	188
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	140
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	138
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	121
Sendotypes predict worsening renal function in chronic kidney disease patients	118
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma	116
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	114
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	111
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	106
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	101
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	89
Mitochondrial and immune response dysregulation in melanoma recurrence	86
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases	84
	83
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	80
Clinical translation potential of self‐inspired live‐cell super‐resolution microscopy	80
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	79
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca²⁺ signalling	78
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	77
Faecal zonulin, calprotectin and the infant microbiome in early life	74
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	73
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	72

Effect of epigenetic treatment on SST₂ expression in neuroendocrine tumour patients	70
Lipids and genes: Regulatory roles of lipids in RNA expression	66
Illuminating the genomic frontier of invasive non‐typhoidal Salmonella infections	66
Deciphering the secret codes in N⁷‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	65
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia	65
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	65
Seize the engine: Emerging cell cycle targets in breast cancer	65
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	64
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	64
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	63
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing	62
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	62
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients	58
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis	57
Glucosamine regulates macrophage function in heart failure	56
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	55
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer	54
The biological burden of conflict across populations worldwide	54
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	54
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	53
Multi‐omics analysis revealed biomarkers for coronary atherosclerosis: Occurrence and development	52
MicroRNAs affecting the susceptibility of melanoma cells to CD8⁺ T cell‐mediated cytolysis	52
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	52
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target	52
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	49
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	49
	49