Clinical and Translational Medicine

Papers
(The median citation count of Clinical and Translational Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway697
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca2+ signalling240
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging208
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design157
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Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases134
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma134
Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals129
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells122
MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell‐mediated cytolysis112
Faecal zonulin, calprotectin and the infant microbiome in early life104
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor99
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases99
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma98
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer96
Glucosamine regulates macrophage function in heart failure95
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC91
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis86
Dissecting the effect of ileal faecal diversion on the intestine using single‐cell sequencing84
Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation81
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease80
High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma77
Effect of epigenetic treatment on SST2 expression in neuroendocrine tumour patients76
Seize the engine: Emerging cell cycle targets in breast cancer75
Mitochondrial and immune response dysregulation in melanoma recurrence75
Lysine‐specific demethylase 1 deletion reshapes tumour microenvironment to overcome acquired resistance to anti‐programmed death 1 therapy in liver cancer74
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma73
Sendotypes predict worsening renal function in chronic kidney disease patients72
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome65
A severe asthma phenotype of excessive airway Haemophilus influenzae relative abundance associated with sputum neutrophilia64
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation63
Molecular and physical technologies for monitoring fluid and electrolyte imbalance: A focus on cancer population60
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma59
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC59
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma58
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives55
Lipids and genes: Regulatory roles of lipids in RNA expression54
Characterization of the tumour microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients54
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways54
Mature dendritic cells enriched in immunoregulatory molecules (mregDCs): A novel population in the tumour microenvironment and immunotherapy target53
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease52
Predictive medicine in a testis trio‐family through a combined multi‐omics approach52
Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases52
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling52
Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis51
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA51
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis50
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Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer‐associated fibroblasts50
PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B‐cell lymphoma49
Translational inhalable extracellular vesicle‐based mRNA therapy for the treatment of lung cancer48
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NDP‐βdmanno‐heptoses are small molecule agonists sensed by the vertebrates to discriminate organisms of different kingdoms48
Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA‐seq48
Inhibition of proteasomal deubiquitinases USP14 and UCHL5 overcomes tyrosine kinase inhibitor resistance in chronic myeloid leukaemia47
Protective function of interleukin‐22 in pulmonary fibrosis47
Unmasking the tumourigenic role of SIN1/MAPKAP1 in the mTOR complex 247
MYTH: An algorithm to score intratumour heterogeneity based on alterations of DNA methylation profiles46
Nano‐optogenetic immunotherapy46
Identification of the c‐Jun/H19/miR‐19/JNK1 cascade during hepatic stellate cell activation46
Clinical medicine journals lag behind science journals with regards to “microbiota sequence” data availability45
Integrated multi‐omics data reveals the molecular subtypes and guides the androgen receptor signalling inhibitor treatment of prostate cancer45
Nanopore sequencing with T2T‐CHM13 for accurate detection and preventing the transmission of structural rearrangements in highly repetitive heterochromatin regions in human embryos44
KDM6A promotes hepatocellular carcinoma progression and dictates lenvatinib efficacy by upregulating FGFR4 expression44
Synergistic inhibition of progesterone receptor‐A/B signalling by simvastatin and mifepristone in human uterine leiomyomas43
Unlocking the potential of T‐cell metabolism reprogramming: Advancing single‐cell approaches for precision immunotherapy in tumour immunity43
Inhibition of autophagy antagonizes breast cancer brain metastogenesis and augments the anticancer activity of lapatinib42
Plasma tsRNAs as novel diagnostic biomarkers for renal cell carcinoma42
Multi‐omics molecular phenotyping reveals the potential mechanisms of chemotherapy response and resistance in small cell lung cancer41
Suicide among patients with cancer: a call to action for researchers and clinical caregivers40
Bmi‐1‐RING1B prevents GATA4‐dependent senescence‐associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA440
Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer40
The genomic and transcriptomic landscapes of clock genes reveal the significance of circadian rhythm in the progression and immune microenvironment of metastatic colorectal cancer40
Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition40
Histone demethylase JMJD1C promotes the polarization of M1 macrophages to prevent glioma by upregulating miR‐302a39
The m5C methyltransferase NSUN2 promotes codon‐dependent oncogenic translation by stabilising tRNA in anaplastic thyroid cancer39
The role of cell‐penetrating peptides in potential anti‐cancer therapy39
The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma38
Differential miRNA plasma profiles associated with the spontaneous loss of HIV‐1 control: miR‐199a‐3p and its potential role as a biomarker for quick screening of elite controllers38
Disproportional enrichment of FoxP3+CD4+ regulatory T cells shapes a suppressive tumour microenvironment in head and neck squamous cell carcinoma36
Blockade of V‐domain immunoglobulin suppressor of T‐cell activation reprograms tumour‐associated macrophages and improves efficacy of PD‐1 inhibitor in gastric cancer35
Transcriptomic evidence of lung repair in paediatric ARDS survival35
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+CAFs in intrahepatic cholangiocarcinoma35
Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone35
GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK235
Illuminating spatial pharmacology with in situ drug imaging34
Plasmatic and myocardial microRNA profiles in patients with Hypertrophic Cardiomyopathy34
Human and mouse non‐targeted metabolomics identify 1,5‐anhydroglucitol as SGLT2‐dependent glycemic marker34
Combination anti‐HIV antibodies to achieve antiretroviral therapy‐free virological suppression in infected individuals34
The prevalence and clinical implication of rare germline deleterious alterations in Chinese patients with prostate cancer: A real‐world multicenter study34
LncRNA nuclear‐enriched abundant transcript 1 shuttled by prostate cancer cells‐secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR‐205‐5p/runt‐related 34
In a search of a protective titer: Do we or do we not need to know?33
TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression33
Interventional‐ and amputation‐stage muscle proteomes in the chronically threatened ischemic limb33
A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity33
Identification of hypoxic macrophages in glioblastoma: Unveiling therapeutic insights from tumour microenvironment analysis33
Microbial and human transcriptome in vaginal fluid at midgestation: Association with spontaneous preterm delivery33
Human mesenchymal stem‐derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat32
Transcriptomic analysis for the retested positive COVID‐19 patients with long‐term persistent SARS‐CoV‐2 but without symptoms in Wuhan32
Involvement of MST1/mTORC1/STAT1 activity in the regulation of B‐cell receptor signalling by chemokine receptor 232
Vitamin D receptor activation in microglia suppresses NOX2‐mediated oxidative damage via PAT1 in vitro and in vivo32
Phosphoproteomics profiling reveals a kinase network conferring acute myeloid leukaemia intrinsic chemoresistance and indicates HMGA1 phosphorylation as a potential influencer32
Biological significance of MYC and CEBPD coamplification in urothelial carcinoma: Multilayered genomic, transcriptional and posttranscriptional positive feedback loops enhance oncogenic 32
Severe dengue in children associates with dysregulation of lipid homeostasis, complement cascade and retinol transport31
Efficacy and safety of pyrotinib combined with albumin‐bound paclitaxel as first‐line treatment for HER2‐positive metastatic breast cancer in patients previously treated with adjuvant and/or neoadjuva30
Ubiquitous regulation of cerebrovascular diseases by ubiquitin‐modifying enzymes30
17‐β‐estradiol reduces surface PD‐L1 expression in estrogen receptor‐positive breast cancer but not type 1 endometrial cancer cells30
Transcriptomic profiling reveals the dynamics of fibrotic progression‐related gene expression into post‐coronavirus disease 2019 pulmonary fibrosis30
Single‐cell sequencing of multi‐region resolves geospatial architecture and therapeutic target of endothelial cells in esophageal squamous cell carcinoma30
Evaluation of on‐ and off‐target effects of self‐assembled epidermal growth factor receptor small interfering RNA delivery system30
Combining single‐cell sequencing to identify key immune genes and construct the prognostic evaluation model for colon cancer patients30
IGF2BP3 mediates the mRNA degradation of NF1 to promote triple‐negative breast cancer progression via an m6A‐dependent manner30
Gene signature related to cancer stem cells and fibroblasts of stem‐like gastric cancer predicts immunotherapy response30
Gestational weight gain in pregnant women with obesity is associated with cord blood DNA methylation, which partially mediates offspring anthropometrics29
Cellular dynamics in tumour microenvironment along with lung cancer progression underscore spatial and evolutionary heterogeneity of neutrophil29
The central role of a two‐way positive feedback pathway in molecular targeted therapies‐mediated pyroptosis in anaplastic thyroid cancer29
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m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency29
Therapeutic targeting of SPIB/SPI1‐facilitated interplay of cancer cells and neutrophils inhibits aerobic glycolysis and cancer progression29
Single‐cell RNA sequencing reveals cellular and molecular reprograming landscape of gliomas and lung cancer brain metastases29
Brain cholesterol therapy for Huntington's disease – Does it make sense?29
WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation29
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A randomized, double‐blind phase 1b study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of the NLRP3 inhibitor selnoflast in patients with moderate to severe active ulcera28
Downregulation of SENP1 impairs nuclear condensation of MEF2C and deteriorates ischemic cardiomyopathy28
The potential of gas plasma technology for targeting breast cancer28
Inhibition of KDM4C/c‐Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism28
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Therapeutic targeting of CNBP phase separation inhibits ribosome biogenesis and neuroblastoma progression via modulating SWI/SNF complex activity28
Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy27
Lysophosphatidylcholine inhibits lung cancer cell proliferation by regulating fatty acid metabolism enzyme long‐chain acyl‐coenzyme A synthase 527
Oncogenic PIK3CA recruits myeloid‐derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5‐lipoxygenase‐dependent arachidonic acid pathway27
Evaluation of pulmonary single‐cell identity specificity in scRNA‐seq analysis26
Interleukin enhancer‐binding factor 2 promotes cell proliferation and DNA damage response in metastatic melanoma26
Managing noradrenaline after traumatic brain injury26
Single‐cell RNA‐seq reveals clonal diversity and prognostic genes of relapsed multiple myeloma26
Multi‐omics analysis of pyroptosis‐related genes for prognosis and immune landscape in head and neck cancer26
Prognostic, clinicopathological, and immune correlation of NLRP3 promoter methylation in kidney renal clear cell carcinoma26
Gene therapy for Whiskott–Aldrich syndrome: The latest news26
Metastasis ability, genomic profile, subtype characteristic and curative efficacy of multiple pulmonary hematogenous metastases in lung cancer26
How the brain produces generalized fear26
Novel deep learning radiomics model for preoperative evaluation of hepatocellular carcinoma differentiation based on computed tomography data26
Single‐cell and bulk characterisation of the distinct immune landscape and possible regulatory mechanisms in coronary plaques vulnerability26
SAA1 and metabolomic signatures predict hyperprogression with immunotherapy in pan cancers26
The immune checkpoints storm in COVID‐19: Role as severity markers at emergency department admission25
Circular RNA LIPH promotes pancreatic cancer glycolysis and progression through sponge miR‐769‐3p and interaction with GOLM125
Single‐nucleus and spatial transcriptomics of paediatric ovary: Molecular insights into the dysregulated signalling pathways underlying premature ovarian insufficiency in classic galactosemia25
CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells25
Human‐host transcriptomic analysis reveals unique early innate immune responses in different sub‐phenotypes of COVID‐1925
Neuronal loss drives differentially expressed protein‐pathways in the PSP globus pallidus25
Ensemble biomarkers for guiding anti‐angiogenesis therapy for ovarian cancer using deep learning25
Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids25
Dynamic alterations of ctDNA associate with the therapeutic outcome in the advanced non‐small cell lung cancer patients who received sintilimab plus anlotinib regime as 1st line therapy25
Hepatic interleukin‐1 receptor type 1 signalling regulates insulin sensitivity in the early phases of nonalcoholic fatty liver disease25
Pyroptosis, metabolism, and tumor immune microenvironment25
RAB2A promotes cervical cancer progression as revealed by comprehensive analysis of HPV integration and proteome in longitudinal cervical samples25
Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies24
SMYD2‐mediated TRAF2 methylation promotes the NF‐κB signaling pathways in inflammatory diseases24
Tumour organoids and assembloids: Patient‐derived cancer avatars for immunotherapy24
BRAFV600E‐PROTAC versus inhibitors in melanoma cells: Deep transcriptomic characterization24
A novel role for interleukin 32 in cholestasis24
Integrated multi‐omics profiling landscape of organising pneumonia24
OTUB1 inhibits breast cancer by non‐canonically stabilizing CCN624
RNA interference therapy for targeting ANGPTL3 and atherogenic lipoproteins: Findings and implications of a recent phase I study24
Crosstalk between m6A modification and alternative splicing during cancer progression24
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Machine learning‐based multi‐omics models for diagnostic classification and risk stratification in diabetic kidney disease23
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Titin gene mutations enhance radiotherapy efficacy via modulation of tumour immune microenvironment in rectum adenocarcinoma23
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Correction to VEGF‐C/VEGFR‐3 axis protects against pressure‐overload‐induced cardiac dysfunction through regulation of lymphangiogenesis23
Smad3‐mediated lncRNA HSALR1 enhances the non‐classic signalling pathway of TGF‐β1 in human bronchial fibroblasts by binding to HSP90AB122
Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption22
Synthetic molecular sensors based on CRISPR‐Cas9 redirect anticancer signal flows to treat retinoblastomas22
Post‐operative minimal residual disease models to study metastatic relapse in soft‐tissue sarcoma patient‐derived xenografts22
Mutations of epigenetic genes and correlation with treatment response in peripheral T‐cell lymphoma22
Interleukin‐2/anti‐interleukin‐2 immune complex attenuates cold ischemia‐reperfusion injury after kidney transplantation by increasing renal regulatory T cells22
Evaluation of vaccine effectiveness against SARS‐CoV‐2 variants by serological epitope profiling22
Single‐cell transcriptome analysis reveals functional changes in tumour‐infiltrating B lymphocytes after chemotherapy in oesophageal squamous cell carcinoma22
Integrated mPD‐L1 and metabolic analysis identifies new prognostic subgroups in lung cancers with wild‐type EGFR22
Translational potential of human brain charts22
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing22
Diagnostic and therapeutic potential of tonic gamma‐aminobutyric acid from reactive astrocytes in brain diseases21
Identification of growth hormone receptor as a relevant target for precision medicine in low‐EGFR expressing glioblastoma21
The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing21
Histone methyltransferase Smyd2 contributes to blood‐brain barrier breakdown in stroke21
Small molecule Z363 co‐regulates TAF10 and MYC via the E3 ligase TRIP12 to suppress tumour growth21
The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia21
Urinary DNA methylation‐based risk stratification model to triage patients for repeat transurethral resection of bladder tumours21
Machine learning algorithms utilizing blood parameters enable early detection of immunethrombotic dysregulation in COVID‐1921
Clinical predictive factors and prediction models for end‐stage renal disease in Chinese patients with type 2 diabetes mellitus21
Snai2‐mediated upregulation of NADSYN1 promotes bladder cancer progression by interacting with PHB21
Single‐cell RNA sequencing in exploring the pathogenesis of diabetic retinopathy21
Human gut‐associated lymphoid tissue: A dynamic hub propagating modulators of inflammation21
How the environment shapes our ability to navigate21
Understanding Omicron: Transmissibility, immune evasion and antiviral intervention21
Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease21
CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model21
Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis21
Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin21
Clinical and molecular features of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma: Results in a multi‐center trial20
Ultrasound‐guided percutaneous metal‐organic frameworks based codelivery system of doxorubicin/acetazolamide for hepatocellular carcinoma therapy20
Preparation for the challenge of heavily mutated Omicron variant20
PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron20
Advanced mutant receptor activator of nuclear factor kappa‐Β ligand development with low affinity for osteoprotegerin20
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P301S‐hTau acetylates KEAP1 to trigger synaptic toxicity via inhibiting NRF2/ARE pathway: A novel mechanism underlying hTau‐induced synaptic toxicities20
CD44v6 chimeric antigen receptor T cell specificity towards AML with FLT3 or DNMT3A mutations20
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Correction to“Splicing factor arginine/serine‐rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome‐based cellular communication”20
Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm20
Serum amlyoid A: An inflammatory adipokine mediating postburn outcomes20
Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype20
Three‐dimensional genome structure shapes the recombination landscape of chromatin features during female germline stem cell development20
KMT2C/D mutations in newly diagnosed acute myeloid leukaemia: Clinical features, genetic co‐occurrences and prognostic significance20
Single‐molecule epiallelic profiling of DNA derived from routinely collected Pap specimens for noninvasive detection of ovarian cancer20
RNA demethylase ALKBH5 promotes colorectal cancer progression by posttranscriptional activation of RAB5A in an m6A‐YTHDF2‐dependent manner20
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Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity19
MiR‐192‐5p/RB1/NF‐κBp65 signaling axis promotes IL‐10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment19
Transcriptomic atlas of GNAT family members in pulmonary epithelia under pathological conditions using single‐cell and bulk cell sequencing19
LEPRE1 shapes a non‐flamed tumour immune landscape and predicts the prognosis in esophageal squamous cell carcinoma19
Rictor/mTORC2 signalling contributes to renal vascular endothelial‐to‐mesenchymal transition and renal allograft interstitial fibrosis by regulating BNIP3‐mediated mitophagy19
Evolution of aberrant brain‐wide spatiotemporal dynamics of resting‐state networks in a Huntington's disease mouse model19
Dissecting the cell of origin of aberrant SALL4 expression in myelodysplastic syndrome19
Distinct discrepancy in breast cancer organoids recapitulation among molecular subtypes revealed by single‐cell transcriptomes analysis19
Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling19
One step forward for nanopore protein sequencing19
Leukemia inhibitory factor receptor homodimerization mediated by acetylation of extracellular lysine promotes prostate cancer progression through the PDPK1/AKT/GCN5 axis19
lncRNA IGF2‐AS regulates miR‐500a‐3p/PPP4R1/p‐VEGFR2 signalling pathway to promote thyroid carcinoma progression and tubulogenesis19
Single‐cell isogrowth profiling: Uniform inhibition uncovers non‐uniform drug responses19
GPR65, a novel regulator of helper T‐cell polarization in inflammatory bowel disease19
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension19
The co‐location of CD14+APOE+ cells and MMP7+ tumour cells contributed to worse immunotherapy response in non‐small cell lung cancer19
Identification of hepatitis B virus infection and integration and its oncogenic role in gastric cancer19
IRF2‐mediated upregulation of lncRNA HHAS1 facilitates the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells by acting as a competing endogenous RNA19
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Prognosis‐oriented molecular subtypes of retroperitoneal liposarcoma18
Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation18
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Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer18
Crosstalk between alternative splicing and inflammatory bowel disease: Basic mechanisms, biotechnological progresses and future perspectives18
Mitochondrial general control of amino acid synthesis 5 like 1 promotes nonalcoholic steatohepatitis development through ferroptosis‐induced formation of neutrophil extracellular traps18
Unconventional microRNA role: Enhancing the human leukocyte antigen class I antigen processing pathway via interacting with a silencer18
A vital step determines the quality of human eggs: Spindle bipolarization18
Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade18
Methionine oxidation of CLK4 promotes the metabolic switch and redox homeostasis in esophageal carcinoma via inhibiting MITF selective autophagy18
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