Clinical and Translational Medicine

Article	Citations
Study on feasibility of the partial meniscal allograft transplantation	622
Metabolomic therapy response prediction in pretherapeutic tissue biopsies for trastuzumab in patients with HER2‐positive advanced gastric cancer	209
Identification and validation of GABA‐driven subtypes and prognosis signature of lung adenocarcinoma	190
Decitabine activates type I interferon signaling to inhibit p53‐deficient myeloid malignant cells	149
Faecal zonulin, calprotectin and the infant microbiome in early life	132
Bortezomib in previously treated phosphatase and tension homology‐deficient patients with advanced intrahepatic cholangiocarcinoma: An open‐label, prospective and single‐centre phase II trial	130
Identification of biomarkers complementary to homologous recombination deficiency for improving the clinical outcome of ovarian serous cystadenocarcinoma	128
Increased oxidized low‐density lipoprotein in mice exposed to a high‐fat diet impaired spermatogenesis by inhibiting testosterone synthesis via the Klk1bs/Eid3 pathway	126
Therapeutic induction of Bcl2‐associated athanogene 3‐mediated autophagy in idiopathic pulmonary fibrosis	125
Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19	119
Colorectal mucinous adenocarcinoma indicates a meaningful subtype: A whole genome sequencing study	109
Immunological evaluation of an mRNA vaccine booster in individuals fully immunized with an inactivated SARS‐CoV‐2 vaccine	108
Genomic profiling of the UFMylation family genes identifies UFSP2 as a potential tumour suppressor in colon cancer	98
Repurposing hyperpolarization‐activated cyclic nucleotide‐gated channels as a novel therapy for breast cancer	93
Spatial transcriptomics reveals regional characteristics of lupus nephritis in murine kidneys and immune response to prednisolone or Gancao Nourishing‐Yin decoction therapies	93
Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases	93
Oestrogen suppresses the adipogenesis of fibro/adipogenic progenitors through reactivating the METTL3–ESR1‐mediated loop in post‐menopausal females	91
Spatial distribution of immune cells and their proximity to STING+ cells are associated with survival in glioblastoma	91
HSPG2 could promote normal haematopoiesis in acute myeloid leukaemia patients after complete remission by repairing bone marrow endothelial progenitor cells	90
Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer	89
Prognosis‐related gene signature is enriched in cancer‐associated fibroblasts in the stem‐like subtype of gastric cancer	80
Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial	78
C1q/TNF‐related protein 4 mediates proliferation and migration of vascular smooth muscle cells during vascular remodelling	77
Immunogenomic alterations of head and neck squamous cell carcinomas stratified by smoking status	77
Molecular and physical technologies for monitoring fluid and electrolyte imbalance: A focus on cancer population	76

FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways	72
Integrating proteomic and clinical data to discriminate major psychiatric disorders: Applications for major depressive disorder, bipolar disorder, and schizophrenia	70
Ketogenic diets in healthy dogs induce gut and serum metabolome changes suggestive of anti‐tumourigenic effects: A model for human ketotherapy trials	70
Targeting KDM4 family epigenetically triggers antitumour immunity via enhancing tumour‐intrinsic innate sensing and immunogenicity	69
Diabetes alters the protein secretome of human adipose‐derived stem cells and promotes tumorigenesis in hepatic cancer cells	66
Cyclin C: A new responser for chemosensitivity in cancer	65
Glucosamine regulates macrophage function in heart failure	61
Revealing the effects of maternal di(2‐ethylhexyl) phthalate exposure on the progression of early meiosis in female foetal germ cells at single‐cell resolution	61
Kynurenine catabolic enzyme KMO regulates HCC growth	59
Heterogeneity in lung cancers by single‐cell DNA sequencing	59
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Genome‐wide profiling of N6‐methyladenosine‐modified pseudogene‐derived long noncoding RNAs reveals the tumour‐promoting and innate immune‐restraining function of RPS15AP12 in ovarian cancer	53
Preclinical B cell depletion and safety profile of a brain‐shuttled crystallizable fragment‐silenced CD20 antibody	53
Nuclear factor erythroid 2‐related factor 2 ameliorates disordered glucose and lipid metabolism in liver: Involvement of gasdermin D in regulating pyroptosis	53
Long noncoding RNA Regulating ImMune Escape regulates mixed lineage leukaemia protein‐1‐H3K4me3‐mediated immune escape in oesophageal squamous cell carcinoma	52
PADI4 facilitates stem‐like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma	52
PIWI‐interacting RNA MIABEPIR regulates cerebral endothelial cell function via DAPK2 pathway in offspring following maternal immune activation	51
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	51
Induction of connective tissue growth factor accounts for the inability of glucocorticoid suppression on pulmonary fibrosis	51
Drug–drug synthetic lethality to combat cancer: From bench to bedside	50
The CYP3A5 genotypes of both liver transplant recipients and donors influence the time‐dependent recovery of tacrolimus clearance during the early stage following transplantation	49
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NAV2 positively modulates inflammatory response of fibroblast‐like synoviocytes through activating Wnt/β‐catenin signaling pathway in rheumatoid arthritis	46
Functional biomarkers that distinguish between tinnitus with and without hyperacusis	46
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C20orf24 promotes colorectal cancer progression by recruiting Rin1 to activate Rab5‐mediated mitogen‑activated protein kinase/extracellular signal‐regulated kinase signalling	46
Dual blocking of PI3K and mTOR signaling by DHW‐221, a novel benzimidazole derivative, exerts antitumor activity in human non‐small cell lung cancer	45
Human tumour vessel heterogeneity in ovarian cancer and its association with response to neoadjuvant chemotherapy	44
ACOD1, rather than itaconate, facilitates p62‐mediated activation of Nrf2 in microglia post spinal cord contusion	44
Issue Information	44
Computational repurposing of oncology drugs through off‐target drug binding interactions from pharmacological databases	43
Predictive medicine in a testis trio‐family through a combined multi‐omics approach	43
Clusterin deficiency is associated with a lack of response to teriflunomide in multiple sclerosis	43
AdjuvareDB: A comprehensive database for candidate adjuvant compendium in clinic	42
Integrated single‐cell RNA sequencing and spatial transcriptomics analysis reveals the tumour microenvironment in patients with endometrial cancer responding to anti‐PD‐1 treatment	42
A pathogenic AKAP4 variant, p.R429H, causes male in/subfertility in humans and mice	41
Integrative genome‐wide chromatin accessibility and transcriptome profiling of diffuse large B‐cell lymphoma	41
Roles of glutamic pyruvate transaminase 2 in reprogramming of airway epithelial lipidomic and metabolomic profiles after smoking	40
Large‐scale genomic sequencing reveals adaptive opportunity of targeting mutated‐PI3Kα in early and advanced HER2‐positive breast cancer	40
MOPSS: Toward high‐fidelity oligonucleotides for clinical applications	39
Multiomics‐based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis	39
From guardian to shepherd: The novel role of p53 in collective cell migration and epithelial repair	39
Clinic‐ready inhibitor of MMP‐9/‐12 restores sensory and functional decline in rodent models of spinal cord injury	39
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Issue Information	38
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YAP/TAZ activation predicts clinical outcomes in mesothelioma and is conserved in in vitro model of driver mutations	37
Hsa_circ_0057105 modulates a balance of epithelial‐mesenchymal transition and ferroptosis vulnerability in renal cell carcinoma	37

Effect of epigenetic treatment on SST2 expression in neuroendocrine tumour patients	37
Healthy and unhealthy plant‐based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes	36
Personalised neoantigen‐based therapy in colorectal cancer	36
m6A‐dependent upregulation of DDX21 by super‐enhancer‐driven IGF2BP2 and IGF2BP3 facilitates progression of acute myeloid leukaemia	36
Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer	36
A novel peptide encoded by circ‐SLC9A6 promotes lipid dyshomeostasis through the regulation of H4K16ac‐mediated CD36 transcription in NAFLD	36
A combination of faecal and intratumour microbial community profiling reveals novel diagnostic and prognostic biomarkers for pancreatic tumours	34
Issue Information	34
Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals	34
Genome‐wide virus‐integration analysis reveals a common insertional mechanism of HPV, HBV and EBV	34
Characterization of the molecular mechanisms underlying azithromycin‐induced cardiotoxicity using human‐induced pluripotent stem cell‐derived cardiomyocytes	34
The roles and therapeutic implications of messenger RNA internal N7‐methylguanosine and N6‐methyladenosine modifications in chemoresistance	34
Protein phosphatase 1 regulatory inhibitor subunit 14C promotes triple‐negative breast cancer progression via sustaining inactive glycogen synthase kinase 3 beta	34
A novel signature based on pairwise PD‐1/PD‐L1 signaling pathway genes for predicting the overall survival in patients with hepatocellular carcinoma	33
CCNB1IP1 prevents ubiquitination‐mediated destabilization of MYCN and potentiates tumourigenesis of MYCN‐amplificated neuroblastoma	33
Clinical implications of EGFR‐associated MAPK/ERK pathway in multiple primary lung cancer	33
Dystrophin immunogenicity and requirement in myogenic cells: Paradigm shift in gene therapy for DMD	33
Post‐transplant cyclophosphamide as sole GHVD prophylaxis after matched reduced‐intensity conditioning allotransplant	33
Evolution of clonal hematopoiesis	33
Corrigendum to “Serglycin‐induced interleukin‐1β from oesophageal cancer cells upregulate hepatocyte growth factor in fibroblasts topromote tumour angiogenesis and growth”	32
Identification and functional analysis of circulating extrachromosomal circular DNA in schizophrenia implicate its negative effect on the disorder	32
Gamma delta T cells in hepatocellular carcinoma: Sunrise of new therapy based on Vδ2 T cells?	32
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RUNX1 mediates the therapeutic effects of mesenchymal stem cells‐derived microparticles in acute respiratory distress syndrome	32
FMO4 shapes immuno‐metabolic reconfiguration in hepatocellular carcinoma	31
Identification of 3′‐terminal 2′‐O‐methylated miRNA in plasma as a novel diagnostic biomarker of NSCLC	31
BCL11B promotes T‐cell acute lymphoblastic leukaemia cell survival via the XRCC5/C11ORF21 axis	31
Paeonol could alleviate diabetes‐related spermatogenic dysfunction via SIRT3‐dependent redox rebalancing	30
RNA‐seq‐driven expression analysis to investigate cardiovascular disease genes with associated phenotypes among atrial fibrillation patients	30
Exploring the potential role of oxidative stress‐related genes in colorectal cancer recurrence and establishing a recurrence assessment system based on single‐cell and bulk RNA‐seq analysis	30
New insights into developmental fate decisions by autoreactive CD4 thymocytes	30
Single‐cell sequencing reveals alterations in the peripheral blood mononuclear cell landscape and monocyte status during colorectal adenocarcinoma formation	29
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Role of integrin expression in the prediction of response to vedolizumab: A prospective real‐life multicentre cohort study	29
Destabilization of microrchidia family CW‐type zinc finger 2 via the cyclin‐dependent kinase 1‐chaperone‐mediated autophagy pathway promotes mitotic arrest and enhances cancer cellular sensitivity to	28
Immunomodulation by intravenous omega‐3 fatty acid treatment in older subjects hospitalized for COVID‐19: A single‐blind randomized controlled trial	28
Discovery of a drug to treat airway mucus hypersecretion	28
Genomic and transcriptomic characterization reveals B‐cell hyperactivation and immune evasion in hepatitis B virus‐associated diffuse large B‐cell lymphoma	28
Emerging role of IκBζ in inflammation: Emphasis on psoriasis	28
The mechanism of liver X receptor regulates the balance of glycoFAsynthesis and cholesterol synthesis in clear cell renal cell carcinoma	28
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	28
Corrigendum to Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	28
On the essentiality of the angiotensin converting enzyme 2 receptor for SARS‐CoV‐2 infection and the potential of soluble angiotensin converting enzyme 2 proteins as universal approach for variants ca	28
HSP90 N‐terminal inhibitors target oncoprotein MORC2 for autophagic degradation and suppress MORC2‐driven breast cancer progression	28
Issue Information	28
Whole‐exome sequencing in clear cell sarcoma of soft tissue uncovers novel prognostic categorization and drug targets	28
Multiplexed plasma protein classifiers for the diagnosis of age‐related macular degeneration	28
How to translate the knowledge of COVID‐19 into the prevention of Omicron variants	28
Potential of peptide‐engineered exosomes with overexpressed miR‐92b‐3p in anti‐angiogenic therapy of ovarian cancer	28
Targeting alarmin release reverses Sjogren's syndrome phenotype by revitalizing Ca2+ signalling	27
Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis‐associated adhesion of ovarian cancer cells	27
Integrative analysis identifies three molecular subsets in ovarian cancer	27
Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor	27
Somatic genomic mosaicism in the brain during aging: Scratching the surface	27
Non‐m6A RNA modifications in haematological malignancies	26
MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell‐mediated cytolysis	26
Integrative multiomics analysis identifies molecular subtypes and potential targets of hepatocellular carcinoma	26
Multi‐omics predictive model based on clinical, radiomic and genomic features for predicting the response of limited‐stage small cell lung cancer to definitive chemoradiotherapy	26
Heavy metals in cigarette smoke strongly inhibit pancreatic ductal function and promote development of chronic pancreatitis	26
Metabolic rescue ameliorates mitochondrial encephalo‐cardiomyopathy in murine and human iPSC models of Leigh syndrome	26
Tumor‐infiltrating CD8+ T cell is prognostic and predicts adjuvant chemotherapy benefit in patients with limited‐stage small cell esophageal carcinoma	25
Lipids and genes: Regulatory roles of lipids in RNA expression	25
A CRISPR/dCasX‐mediated transcriptional programming system for inhibiting the progression of bladder cancer cells by repressing c‐MYC or activating TP53	25
Extracellular vesicle‐packaged mitochondrial disturbing miRNA exacerbates cardiac injury during acute myocardial infarction	25
Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis	25
Real‐time longitudinal analysis of human gliomas reveals in vivo genome evolution and therapeutic impact under standardized treatment	25
Real‐world evidence for preventive effects of statins on cancer incidence: A trans‐Atlantic analysis	25
Serum amyloid A promotes emphysema by triggering the reciprocal activation of neutrophils and ILC3s	25
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	25
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	25
Oocyte‐specific deletion of eukaryotic translation initiation factor 5 causes apoptosis of mouse oocytes within the early‐growing follicles by mitochondrial fission defect‐reactive oxygen species‐DNA	24
NLRP3 activation maintains intestinal epithelial barrier and reduces liver injury in alcoholic liver disease mice	24
Reinventing magnetic resonance imaging for accessible healthcare: Whole‐body imaging at 0.05 Tesla	24
A metastasis‐associated microRNA‐based liquid biopsy signature for risk‐stratification in colorectal cancer: a multicenter cohort study	24
Measuring single‐cell immune clonality to track haematological cancers	24
The future of G protein‐coupled receptor therapeutics: Apelin receptor acts as a prototype for the advancement of precision drug design	24
Non‐coding RNAs and colitis‐associated cancer: Mechanisms and clinical applications	24
Early postoperative plasma circulating tumour DNA for molecular residue disease detection and recurrence risk evaluation in surgical non‐small cell lung cancer	24
Adipose tissue‐derived extracellular vesicles aggravate temporomandibular joint osteoarthritis associated with obesity	23
Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade	23

Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGFR	23
EHMT2‐mediated R‐loop formation promotes the malignant progression of prostate cancer via activating Aurora B	23
Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury	23
Cannabinoid receptor 2 facilitates the Schwann cells‐dependent peripheral nerve regeneration	23
Predictive nomogram integrating radiomics and multi‐omics for improved prognosis‐model in cholangiocarcinoma	23
Mesoscopic connectome enters the new age of single‐neuron projectome	23
Deciphering the pseudouridine nucleobase modification in human diseases: From molecular mechanisms to clinical perspectives	23
Statistical and computational methods for enabling the clinical and translational application of spatial transcriptomics	22
A vital step determines the quality of human eggs: Spindle bipolarization	22
Comprehensive mapping of somatotroph pituitary neuroendocrine tumour heterogeneity using spatial and single‐cell transcriptomics	22
RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma	22
Importance of integrating epidemiological and genomic surveillance of seasonal influenza viruses to monitor global circulation	22
The generation of a neuronal phase code for space	22
Induced collagen type‐I secretion by hepatocytes of the melanoma liver metastasis is associated with a reduction in tumour‐infiltrating lymphocytes	22
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PARylation of HMGA1 desensitizes esophageal squamous cell carcinoma to olaparib	22
Targeting endoplasmic reticulum stress‐induced lymphatic dysfunction for mitigating bisphosphonate‐related osteonecrosis	22
Chitinase 3‐like 1 is neurotoxic in multiple sclerosis patient‐derived cortical neurons	22
Stratifin (SFN) regulates lung cancer progression via nucleating the Vps34‐BECN1‐TRAF6 complex for autophagy induction	21
Identification of a novel therapeutic target underlying atypical manifestation of Gaucher disease	21
A biobanking turning‐point in the use of formalin‐fixed, paraffin tumor blocks to unveil kinase signaling in melanoma	21
Dynamic changes in DNA methylation and hydroxymethylation revealed the transformation of advanced adenoma into colorectal carcinoma	21
From mental strain to gut pain: A brain‐gut pathway transducing psychological stress to intestinal inflammation	21
The human melanoma proteome atlas—Defining the molecular pathology	21
Mass spectrometry‐based proteomics analysis of human globus pallidus from progressive supranuclear palsy patients discovers multiple disease pathways	21
Deep learning‐based multi‐omics study reveals the polymolecular phenotypic of diabetic kidney disease	21
HBV‐integrated local genomic alterations reveal multicentric independent occurrences of multifocal HCC	21
Comprehensive methylome sequencing reveals prognostic epigenetic biomarkers for prostate cancer mortality	21
Dormant cancer cells and polyploid giant cancer cells: The roots of cancer recurrence and metastasis	20
Cefoselis enhances breast cancer chemosensitivity by directly targeting GRP78/LRP5 signalling of cancer stem cells	20
The volatile and heterogeneous gut microbiota shifts of COVID‐19 patients over the course of a probiotics‐assisted therapy	20
The PPARγ pathway determines electrophysiological remodelling and arrhythmia risks in DSC2 arrhythmogenic cardiomyopathy	20
Selenium sulfide disrupts the PLAGL2/C‐MET/STAT3‐induced resistance against mitochondrial apoptosis in hepatocellular carcinoma	20
EEF2K silencing inhibits tumour progression through repressing SPP1 and synergises with BET inhibitors in melanoma	20
PROM2 overexpression induces metastatic potential through epithelial‐to‐mesenchymal transition and ferroptosis resistance in human cancers	20
Iron controls T helper cell pathogenicity by promoting glucose metabolism in autoimmune myopathy	20
RNA methylation‐related inhibitors: Biological basis and therapeutic potential for cancer therapy	19
Diagnostic and prognostic potential of the oral and gut microbiome for lung adenocarcinoma	19
Identification and characterization of novel CD274 (PD‐L1) regulating microRNAs and their functional relevance in melanoma	19
Complete loss of the atrial natriuretic peptide‐converting enzyme Corin and CHAF‐LA syndrome: Implications to natriuretic peptide physiology and left atrium health	19
Single‐cell sequencing of mouse heart cellular heterogeneity in hypercholesterolemia reveals the mechanism of myocardial damage	19
B‐cell lymphoma‐3 controls mesenchymal stem cell commitment and senescence during skeletal aging	19
Identification of clinically actionable secondary genetic variants from whole‐genome sequencing in a large‐scale Chinese population	19
SCF‐FBXL8 contributes to liver metastasis and stem‐cell‐like features in colorectal cancer cells by mediating ubiquitination and degradation of TP53	19
The roles of innate and adaptive immunity in inactivated viral vaccination‐mediated protection against COVID‐19	19
Neutrophil to lymphocyte ratio as a predictor for treatment of radiation‐induced brain necrosis with bevacizumab in nasopharyngeal carcinoma patients	19
Selective degradation of the p53‐R175H oncogenic hotspot mutant by an RNA aptamer‐based PROTAC	19
A single‐cell atlas of bisphenol A (BPA)‐induced testicular injury in mice	19
Towards next‐generation TIL therapy: TILs enriched in neoepitope‐specific T cells	19
Issue Information	19
Single‐cell RNA sequencing reveals SERPINE1‐expressing CAFs remodelling tumour microenvironment in recurrent osteosarcoma	18
The juxtaposition of Ilex cornuta fruit and gut microbiota against alcoholic liver disease based on the integrated pharmacology via metabolomics	18
Cell‐free RNA and fully convolutional dense network‐based early preeclampsia prediction	18
PD‐L1/TIGIT bispecific antibody showed survival advantage in animal model	18
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Profiling of host entry factors in adults and fetuses for severe acute respiratory syndrome coronavirus‐2 infection indicates its developmental regulation	18
Cyclin‐dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration‐resistant prostate cancer	18
Correlation of vaccine‐elicited antibody levels and neutralizing activities against SARS‐CoV‐2 and its variants	18
N6‐methyladenosine‐RNA methylation promotes expression of solute carrier family 7 member 11, an uptake transporter of cystine for lipid reactive oxygen species scavenger glutathione	18
Advances in understanding the immunity of the brain and its borders: Focus on brain macrophages	18
TFH2 cells associate with enhanced humoral immunity to SARS‐CoV‐2 inactivated vaccine in patients with allergic rhinitis	18
Lack of protective effect of CCR3 blockade during experimental colitis may be related to CCR3 expression by colonic Tregs	18
Seize the engine: Emerging cell cycle targets in breast cancer	18
New strategy for suppressing the growth of lung cancer cells harboring mutations in the ATP‐binding region of EGFR by targeting the molecular motor MYO1D	18
Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD‐mediated pyroptosis in colorectal cancer	18
Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology	17
TLR4 aggravates microglial pyroptosis by promoting DDX3X‐mediated NLRP3 inflammasome activation via JAK2/STAT1 pathway after spinal cord injury	17
Ecological and evolutionary dynamics to design and improve ovarian cancer treatment	17
Somatic mutations in homologous recombination pathway predict favourable prognosis after immunotherapy across multiple cancer types	17
A hidden proteome encoded by circRNAs in human placentas: Implications for uncovering preeclampsia pathogenesis	17
Ubiquitin: Not just a one‐way ticket to the proteasome, but a therapeutic dial to fine‐tune the molecular landscape of disease	17
Cancer‐associated fibroblasts mediate resistance to neoadjuvant therapy in breast cancer	17
Lipolysis by pancreatic cancer‐derived extracellular vesicles in cancer‐associated cachexia via specific integrins	17
Identification of IKZF1 genetic mutations as new molecular subtypes in acute myeloid leukaemia	17
Disentangling the molecular mystery of tumour–microbiota interactions: Microbial metabolites	17
Unveiling the functional roles of patient‐derived tumour organoids in assessing the tumour microenvironment and immunotherapy	17
LncRNA NEAT1 suppresses cellular senescence in hepatocellular carcinoma via KIF11‐dependent repression of CDKN2A	17
Long non‐coding RNA VAL facilitates PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer	17
N‐acetyltransferase 10 facilitates tumorigenesis of diffuse large B‐cell lymphoma by regulating AMPK/mTOR signalling through N4‐acetylcytidine modification of SLC30A9	17
HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice	17
Mitochondrial and immune response dysregulation in melanoma recurrence	17
Protein disulfide isomerase a4 promotes lung cancer development via the Stat3 pathway in stromal cells	17
The WNK1–ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib	17
Single‐cell multi‐modal chromatin profiles revealing epigenetic regulations of cells in hepatocellular carcinoma	17
Impact of restoring male fertility with transplantation of in vitro propagated spermatogonial stem cells on the health of their offspring throughout life	17
Vaginal delivery provides skin colonization resistance from environmental microbes in the NICU	17
Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: Oncometabolite fuels oncogenic transcription	17
A multi‐omics study delineates new molecular features and therapeutic targets for esophageal squamous cell carcinoma	16
Forward single‐cell sequencing into clinical application: Understanding of cancer microenvironment at single‐cell solution	16
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Integrating single‐cell RNA sequencing with spatial transcriptomics reveals an immune landscape of human myometrium during labour	16
Baseline microbiome and metabolome are associated with response to ITIS diet in an exploratory trial in patients with rheumatoid arthritis	16
Structural inequality and temporal brain dynamics across diverse samples	16
Intratumoural microbiome can predict the prognosis of hepatocellular carcinoma after surgery	16
Serum tsRNA as a novel molecular diagnostic biomarker for lupus nephritis	16