Clinical and Translational Medicine

Article	Citations
Single‐cell RNA sequencing technologies and applications: A brief overview	255
Cytosolic DNA‐STING‐NLRP3 axis is involved in murine acute lung injury induced by lipopolysaccharide	141
Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity	122
Pyroptosis, metabolism, and tumor immune microenvironment	120
The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID‐19	114
CD73 alleviates GSDMD‐mediated microglia pyroptosis in spinal cord injury through PI3K/AKT/Foxo1 signaling	108
Emerging roles of exosomal miRNAs in diabetes mellitus	97
METTL1‐m7G‐EGFR/EFEMP1 axis promotes the bladder cancer development	88
Anti‐inflammatory hydrogel dressings and skin wound healing	87
METTL1 promotes hepatocarcinogenesis via m7G tRNA modification‐dependent translation control	87
Tumor‐derived exosomal miR‐19b‐3p facilitates M2 macrophage polarization and exosomal LINC00273 secretion to promote lung adenocarcinoma metastasis via Hippo pathway	86
Evaluation of the safety and efficacy of using human menstrual blood‐derived mesenchymal stromal cells in treating severe and critically ill COVID‐19 patients: An exploratory clinical trial	86
FTO modifies the m6A level of MALAT and promotes bladder cancer progression	78
COVID‐19 critical illness pathophysiology driven by diffuse pulmonary thrombi and pulmonary endothelial dysfunction responsive to thrombolysis	78
MUC4, MUC16, and TTN genes mutation correlated with prognosis, and predicted tumor mutation burden and immunotherapy efficacy in gastric cancer and pan‐cancer	77
Deubiquitinase USP35 modulates ferroptosis in lung cancer via targeting ferroportin	76
The potential impact of ChatGPT in clinical and translational medicine	76
HucMSC‐exosomes carrying miR‐326 inhibit neddylation to relieve inflammatory bowel disease in mice	75
Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfun	74
m6A modification of lncRNA PCAT6 promotes bone metastasis in prostate cancer through IGF2BP2‐mediated IGF1R mRNA stabilization	73
Serum irisin levels are decreased in patients with sepsis, and exogenous irisin suppresses ferroptosis in the liver of septic mice	72
Revealing the transcriptional heterogeneity of organ‐specific metastasis in human gastric cancer using single‐cell RNA Sequencing	65
Lactobacillus lactis and Pediococcus pentosaceus‐driven reprogramming of gut microbiome and metabolome ameliorates the progression of non‐alcoholic fatty liver disease	61
EMT‐cancer cells‐derived exosomal miR‐27b‐3p promotes circulating tumour cells‐mediated metastasis by modulating vascular permeability in colorectal cancer	59
COVID‐19 diagnostic testing: Technology perspective	57

The function of LncRNAs and their role in the prediction, diagnosis, and prognosis of lung cancer	57
Research trends in pharmacological modulation of tumor‐associated macrophages	56
Understanding cell‐cell communication and signaling in the colorectal cancer microenvironment	56
Spatial omics: Navigating to the golden era of cancer research	56
Landscape and dynamics of single tumor and immune cells in early and advanced‐stage lung adenocarcinoma	55
Membrane engineering of cell membrane biomimetic nanoparticles for nanoscale therapeutics	55
The umbilical cord mesenchymal stem cell‐derived exosomal lncRNA H19 improves osteochondral activity through miR‐29b‐3p/FoxO3 axis	54
The opportunities and pitfalls of ChatGPT in clinical and translational medicine	53
Long noncoding RNA CASC11 promotes hepatocarcinogenesis and HCC progression through EIF4A3‐mediated E2F1 activation	53
Deep learning‐based classification and mutation prediction from histopathological images of hepatocellular carcinoma	52
Single‐cell transcriptome atlas of human mesenchymal stem cells exploring cellular heterogeneity	52
NAT10‐mediated mRNA N4‐acetylcytidine modification promotes bladder cancer progression	51
LncRNA LINC00942 promotes chemoresistance in gastric cancer by suppressing MSI2 degradation to enhance c‐Myc mRNA stability	50
Tumor‐derived exosomal BCYRN1 activates WNT5A/VEGF‐C/VEGFR3 feedforward loop to drive lymphatic metastasis of bladder cancer	50
Multiregion single‐cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancer	49
Mental health status and related influencing factors of COVID‐19 survivors in Wuhan, China	49
Apolipoprotein C‐II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway	49
Contrast‐enhanced CT radiomics for preoperative evaluation of microvascular invasion in hepatocellular carcinoma: A two‐center study	48
Loss of m6A demethylase ALKBH5 promotes post‐ischemic angiogenesis via post‐transcriptional stabilization of WNT5A	48
Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis	47
Hsa_circ_0001666 suppresses the progression of colorectal cancer through the miR‐576‐5p/PCDH10 axis	47
The omicron variant of SARS‐CoV‐2: Understanding the known and living with unknowns	47
T‐cell activation and immune memory enhancement induced by irreversible electroporation in pancreatic cancer	47
Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non‐small cell lung cancer	47
Influence of oncogenic mutations and tumor microenvironment alterations on extranodal invasion in diffuse large B‐cell lymphoma	47
Glutathione peroxidase 4‐dependent glutathione high‐consumption drives acquired platinum chemoresistance in lung cancer‐derived brain metastasis	46
CD13 promotes hepatocellular carcinogenesis and sorafenib resistance by activating HDAC5‐LSD1‐NF‐κB oncogenic signaling	46
Modulation of gut microbiota mediates berberine‐induced expansion of immuno‐suppressive cells to against alcoholic liver disease	45
The N6‐methyladenosine modification enhances ferroptosis resistance through inhibiting SLC7A11 mRNA deadenylation in hepatoblastoma	45
The roles of exosomes in cancer drug resistance and its therapeutic application	44
Single‐cell analyses reveal suppressive tumor microenvironment of human colorectal cancer	43
The role of cell‐penetrating peptides in potential anti‐cancer therapy	42
TCONS_00012883 promotes proliferation and metastasis via DDX3/YY1/MMP1/PI3K‐AKT axis in colorectal cancer	42
Irisin attenuates myocardial ischemia/reperfusion‐induced cardiac dysfunction by regulating ER‐mitochondria interaction through a mitochondrial ubiquitin ligase‐dependent mechanism	41
The future of ChatGPT in academic research and publishing: A commentary for clinical and translational medicine	41
AMD1 upregulates hepatocellular carcinoma cells stemness by FTO mediated mRNA demethylation	41
Interplay of m6A and histone modifications contributes to temozolomide resistance in glioblastoma	40
Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1–Wnt/β‐catenin–TFE3 feedback loop signalling	40
Cyclosporine modulates neutrophil functions via the SIRT6–HIF‐1α–glycolysis axis to alleviate severe ulcerative colitis	39
Rebalancing TGF‐β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis	38
Time course of endothelial dysfunction markers and mortality in COVID‐19 patients: A pilot study	38
Circulating tumor cell characterization of lung cancer brain metastases in the cerebrospinal fluid through single‐cell transcriptome analysis	37
EASY‐APP: An artificial intelligence model and application for early and easy prediction of severity in acute pancreatitis	37
Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α	37
A phase I study of anti‐BCMA CAR T cell therapy in relapsed/refractory multiple myeloma and plasma cell leukemia	36
Downregulation of microRNA‐6125 promotes colorectal cancer growth through YTHDF2‐dependent recognition of N6‐methyladenosine‐modified GSK3β	36
A novel RANKL‐targeted flavonoid glycoside prevents osteoporosis through inhibiting NFATc1 and reactive oxygen species	36
LAG3 and its emerging role in cancer immunotherapy	36
Suppression of lncRNA MALAT1 by betulinic acid inhibits hepatocellular carcinoma progression by targeting IAPs via miR‐22‐3p	36
Oxidative stress induces monocyte‐to‐myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma	35

Hypoxia‐induced FOXO4/LDHA axis modulates gastric cancer cell glycolysis and progression	35
The metastatic promoter DEPDC1B induces epithelial‐mesenchymal transition and promotes prostate cancer cell proliferation via Rac1‐PAK1 signaling	35
Single‐cell transcriptomes reveal heterogeneity of high‐grade serous ovarian carcinoma	35
Functional inhibition of lactate dehydrogenase suppresses pancreatic adenocarcinoma progression	34
Circle‐Seq reveals genomic and disease‐specific hallmarks in urinary cell‐free extrachromosomal circular DNAs	33
Integrative multiomics analysis of human atherosclerosis reveals a serum response factor‐driven network associated with intraplaque hemorrhage	33
LncRNA nuclear‐enriched abundant transcript 1 shuttled by prostate cancer cells‐secreted exosomes initiates osteoblastic phenotypes in the bone metastatic microenvironment via miR‐205‐5p/runt‐related	33
Clinical characteristics and risk factors for mortality among inpatients with COVID‐19 in Wuhan, China	32
Vitamin D3 ameliorates nitrogen mustard‐induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3–SOD2–mtROS signaling pathway	32
Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid‐induced osteonecrosis of the femoral head	32
MAFG‐AS1 promotes tumor progression via regulation of the HuR/PTBP1 axis in bladder urothelial carcinoma	31
Role of endothelial cells in tumor microenvironment	31
Diagnosing mild traumatic brain injury using saliva RNA compared to cognitive and balance testing	30
Keeping an eye on circadian time in clinical research and medicine	30
Somatic mutations in homologous recombination pathway predict favourable prognosis after immunotherapy across multiple cancer types	30
Prognostic value of early leukocyte fluctuations for recovery from traumatic spinal cord injury	30
Novel circular RNA circSOBP governs amoeboid migration through the regulation of the miR‐141‐3p/MYPT1/p‐MLC2 axis in prostate cancer	30
Thalidomide combined with low‐dose short‐term glucocorticoid in the treatment of critical Coronavirus Disease 2019	29
Integrated biomarker profiling of the metabolome associated with impaired fasting glucose and type 2 diabetes mellitus in large‐scale Chinese patients	29
Treg deficiency‐mediated TH1 response causes human premature ovarian insufficiency through apoptosis and steroidogenesis dysfunction of granulosa cells	29
Extracellular vesicles from human multipotent stromal cells protect against hearing loss after noise trauma in vivo	29
Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A	29
LINC01133 promotes hepatocellular carcinoma progression by sponging miR‐199a‐5p and activating annexin A2	29
Hypoxia‐induced cofilin 1 promotes hepatocellular carcinoma progression by regulating the PLD1/AKT pathway	29
Patient‐derived renal cell carcinoma organoids for personalized cancer therapy	28
Histone demethylase JMJD1C promotes the polarization of M1 macrophages to prevent glioma by upregulating miR‐302a	28
Dimethyl fumarate prevents ferroptosis to attenuate acute kidney injury by acting on NRF2	28
Progress and applications of mass cytometry in sketching immune landscapes	28
The “sugar‐coated bullets” of cancer: Tumor‐derived exosome surface glycosylation from basic knowledge to applications	28
Extracellular matrix and Hippo signaling as therapeutic targets of antifibrotic compounds for uterine fibroids	28
A methyltransferase‐like 14/miR‐99a‐5p/tribble 2 positive feedback circuit promotes cancer stem cell persistence and radioresistance via histone deacetylase 2‐mediated epigenetic modulation in esophag	27
Claudin‐2 promotes colorectal cancer growth and metastasis by suppressing NDRG1 transcription	27
Multi‐omics consensus ensemble refines the classification of muscle‐invasive bladder cancer with stratified prognosis, tumour microenvironment and distinct sensitivity to frontline therapies	27
S100A7 as a potential diagnostic and prognostic biomarker of esophageal squamous cell carcinoma promotes M2 macrophage infiltration and angiogenesis	27
m6A hypomethylation of DNMT3B regulated by ALKBH5 promotes intervertebral disc degeneration via E4F1 deficiency	27
Arsenic trioxide induces differentiation of cancer stem cells in hepatocellular carcinoma through inhibition of LIF/JAK1/STAT3 and NF‐kB signaling pathways synergistically	27
Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial	27
Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer	27
A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6	27
VEGF‐C/VEGFR‐3 axis protects against pressure‐overload induced cardiac dysfunction through regulation of lymphangiogenesis	27
Interactions between ibuprofen, ACE2, renin‐angiotensin system, and spike protein in the lung. Implications for COVID‐19	26
Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer	26
TLR4 aggravates microglial pyroptosis by promoting DDX3X‐mediated NLRP3 inflammasome activation via JAK2/STAT1 pathway after spinal cord injury	26
Circular CPM promotes chemoresistance of gastric cancer via activating PRKAA2‐mediated autophagy	26
Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA	26
Predicting treatment response to neoadjuvant chemoradiotherapy in local advanced rectal cancer by biopsy digital pathology image features	26
CD47‐SIRPα blocking‐based immunotherapy: Current and prospective therapeutic strategies	26
Milk fat globule EGF factor 8 restores mitochondrial function via integrin‐medicated activation of the FAK‐STAT3 signaling pathway in acute pancreatitis	25
MiRNA‐516a promotes bladder cancer metastasis by inhibiting MMP9 protein degradation via the AKT/FOXO3A/SMURF1 axis	25
The novel role of circular RNA ST3GAL6 on blocking gastric cancer malignant behaviours through autophagy regulated by the FOXP2/MET/mTOR axis	25
YTHDF2 promotes intrahepatic cholangiocarcinoma progression and desensitises cisplatin treatment by increasing CDKN1B mRNA degradation	25
Emerging roles of the solute carrier family in pancreatic cancer	25
Potential of peptide‐engineered exosomes with overexpressed miR‐92b‐3p in anti‐angiogenic therapy of ovarian cancer	25
Vaccine‐breakthrough infection by the SARS‐CoV‐2 omicron variant elicits broadly cross‐reactive immune responses	25
Dissecting the role of cancer‐associated fibroblast‐derived biglycan as a potential therapeutic target in immunotherapy resistance: A tumor bulk and single‐cell transcriptomic study	24
Identification of tumor‐associated macrophage subsets that are associated with breast cancer prognosis	24
Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro‐osteogenic paracrine response: TERCELOI clinical trial	24
Long noncoding RNA IL6‐AS1 is highly expressed in chronic obstructive pulmonary disease and is associated with interleukin 6 by targeting miR‐149‐5p and early B‐cell factor 1	24
TGF‐β signaling in liver metastasis	24
Mechanisms of interactions between lung‐origin telocytes and mesenchymal stem cells to treat experimental acute lung injury	23
Exosome‐transmitted miR‐769‐5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53	23
In vivo and in vitro activation of dormant primordial follicles by EGF treatment in mouse and human	23
Definition of erythroid cell‐positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection	23
Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation	23
Multi‐omic landscaping of human midbrains identifies disease‐relevant molecular targets and pathways in advanced‐stage Parkinson's disease	23
Circulating tumor cells are an indicator for the administration of adjuvant transarterial chemoembolization in hepatocellular carcinoma: A single‐center, retrospective, propensity‐matched study	23
Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2‐targeted therapies	22
Instantaneous “catch‐and‐kill” inactivation of SARS‐CoV‐2 by nitride ceramics	22
Multiplex immunofluorescence and single‐cell transcriptomic profiling reveal the spatial cell interaction networks in the non‐small cell lung cancer microenvironment	22
The volatile and heterogeneous gut microbiota shifts of COVID‐19 patients over the course of a probiotics‐assisted therapy	22
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1	22
Genetic modifiers of long‐term survival in sickle cell anemia	22
Combined treatment with anti‐PSMA CAR NK‐92 cell and anti‐PD‐L1 monoclonal antibody enhances the antitumour efficacy against castration‐resistant prostate cancer	22
BRD4‐IRF1 axis regulates chemoradiotherapy‐induced PD‐L1 expression and immune evasion in non‐small cell lung cancer	22
Hypoxic colorectal cancer‐derived extracellular vesicles deliver microRNA‐361‐3p to facilitate cell proliferation by targeting TRAF3 via the noncanonical NF‐κB pathways	22
Therapeutic targeting of SPIB/SPI1‐facilitated interplay of cancer cells and neutrophils inhibits aerobic glycolysis and cancer progression	22
Diversity and intratumoral heterogeneity in human gallbladder cancer progression revealed by single‐cell RNA sequencing	22
Natural HDAC‐1/8 inhibitor baicalein exerts therapeutic effect in CBF‐AML	21
Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer	21
Spatiotemporal molecular medicine: A new era of clinical and translational medicine	21

Glioma glycolipid metabolism: MSI2–SNORD12B–FIP1L1–ZBTB4 feedback loop as a potential treatment target	21
Alzheimer's disease: An evolving understanding of noradrenergic involvement and the promising future of electroceutical therapies	21
How to translate the knowledge of COVID‐19 into the prevention of Omicron variants	21
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells	21
SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose‐derived mesenchymal stem cells via metabolic switching	21
Composition of the murine gut microbiome impacts humoral immunity induced by rabies vaccines	21
FABP4 deactivates NF‐κB‐IL1α pathway by ubiquitinating ATPB in tumor‐associated macrophages and promotes neuroblastoma progression	21
Activation of Toll‐like receptor 7 provides cardioprotection in septic cardiomyopathy‐induced systolic dysfunction	21
A comprehensive and universal approach for embryo testing in patients with different genetic disorders	21
Hyperprogression: A novel response pattern under immunotherapy	20
BRD4 regulates self‐renewal ability and tumorigenicity of glioma‐initiating cells by enrichment in the Notch1 promoter region	20
Effects of thoracic nerve block on perioperative lung injury, immune function, and recovery after thoracic surgery	20
Deciphering DSC2 arrhythmogenic cardiomyopathy electrical instability: From ion channels to ECG and tailored drug therapy	20
Time‐restricted feeding improves the reproductive function of female mice via liver fibroblast growth factor 21	20
Mental health and psychosocial function of general population during the COVID‐19 epidemic in China	20
Improving mitochondria and ER stability helps eliminate upper motor neuron degeneration that occurs due to mSOD1 toxicity and TDP‐43 pathology	20
The roles of E3 ubiquitin ligases in cancer progression and targeted therapy	20
Combined detection of aneuploid circulating tumor‐derived endothelial cells and circulating tumor cells may improve diagnosis of early stage non‐small‐cell lung cancer	20
A long non‐coding RNA signature for diagnostic prediction of sepsis upon ICU admission	20
ANXA6 suppresses the tumorigenesis of cervical cancer through autophagy induction	20
Quantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B‐related hepatocellular carcinoma	20
Patient‐derived organoids for personalized gallbladder cancer modelling and drug screening	20
Identification of biomarkers complementary to homologous recombination deficiency for improving the clinical outcome of ovarian serous cystadenocarcinoma	20
The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease	20
N6‐methyladenosine‐modified lncRNA ARHGAP5‐AS1 stabilises CSDE1 and coordinates oncogenic RNA regulons in hepatocellular carcinoma	20
Potential biomarkers and targets of mitochondrial dynamics	20
Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling	19
A cellular census of human peripheral immune cells identifies novel cell states in lung diseases	19
A three‐lncRNA signature of pretreatment biopsies predicts pathological response and outcome in esophageal squamous cell carcinoma with neoadjuvant chemoradiotherapy	19
ZNF677 suppresses renal cell carcinoma progression through N6‐methyladenosine and transcriptional repression of CDKN3	19
Knockdown of lactate dehydrogenase by adeno‐associated virus‐delivered CRISPR/Cas9 system alleviates primary hyperoxaluria type 1	19
Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling	19
The prognostic value and molecular properties of tertiary lymphoid structures in oesophageal squamous cell carcinoma	19
TGF‐β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation	19
ISG15 deficiency features a complex cellular phenotype that responds to treatment with itaconate and derivatives	19
Evidence for endothelial‐to‐mesenchymal transition in human brain arteriovenous malformations	19
Serum extracellular vesicles containing MIAT induces atrial fibrosis, inflammation and oxidative stress to promote atrial remodeling and atrial fibrillation via blockade of miR‐485‐5p‐mediated CXCL10	19
Synchronous ground‐glass nodules showed limited response to anti‐PD‐1/PD‐L1 therapy in patients with advanced lung adenocarcinoma	19
Nicotinamide‐N‐methyltransferase is a promising metabolic drug target for primary and metastatic clear cell renal cell carcinoma	19
NOX5 mediates the crosstalk between tumor cells and cancer‐associated fibroblasts via regulating cytokine network	18
Androgen receptor decreases renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis	18
The central role of a two‐way positive feedback pathway in molecular targeted therapies‐mediated pyroptosis in anaplastic thyroid cancer	18
A novel potential target of IL‐35‐regulated JAK/STAT signaling pathway in lupus nephritis	18
Clinically relevant preclinical animal models for testing novel cranio‐maxillofacial bone 3D‐printed biomaterials	18
Decoding of exosome heterogeneity for cancer theranostics	18
Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin	18
4‐phenylbutyric acid promotes hepatocellular carcinoma via initiating cancer stem cells through activation of PPAR‐α	18
Identification and validation of prognosis‐related DLX5 methylation as an epigenetic driver in myeloid neoplasms	18
N6‐methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation	18
Integrated microbiome, metabolome, and proteome analysis identifies a novel interplay among commensal bacteria, metabolites and candidate targets in non‐small cell lung cancer	18
Preclinical platforms to study therapeutic efficacy of human γδ T cells	18
Spatiotemporal molecular imaging is a critical part of spatiotemporal molecular medicine	18
Regulatory roles of external cholesterol in human airway epithelial mitochondrial function through STARD3 signalling	18
Protective function of interleukin‐22 in pulmonary fibrosis	18
Pyrotinib combined with CDK4/6 inhibitor in HER2‐positive metastatic gastric cancer: A promising strategy from AVATAR mouse to patients	18
Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double‐blind, place	18
IL‐22‐mediated renal metabolic reprogramming via PFKFB3 to treat kidney injury	17
Intraoperative near‐infrared II window fluorescence imaging‐assisted nephron‐sparing surgery for complete resection of cystic renal masses	17
GPR65 promotes intestinal mucosal Th1 and Th17 cell differentiation and gut inflammation through downregulating NUAK2	17
The Human Melanoma Proteome Atlas—Complementing the melanoma transcriptome	17
A multi‐omics study delineates new molecular features and therapeutic targets for esophageal squamous cell carcinoma	17
FTO promotes colorectal cancer progression and chemotherapy resistance via demethylating G6PD/PARP1	17
Bromelain inhibits SARS‐CoV‐2 infection via targeting ACE‐2, TMPRSS2, and spike protein	17
Adipose‐specific ATGL ablation reduces burn injury‐induced metabolic derangements in mice	17
A metagenomic study of biliary microbiome change along the cholecystitis‐carcinoma sequence	17
Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple‐negative breast cancers	17
Histone acetyltransferase 1 upregulates androgen receptor expression to modulate CRPC cell resistance to enzalutamide	17
Engineering chimeric antigen receptor T cells for solid tumour therapy	17
circKCNN2 suppresses the recurrence of hepatocellular carcinoma at least partially via regulating miR‐520c‐3p/methyl‐DNA‐binding domain protein 2 axis	17
The role of neutrophil extracellular traps in cancer metastasis	17
Immunomodulation by intravenous omega‐3 fatty acid treatment in older subjects hospitalized for COVID‐19: A single‐blind randomized controlled trial	17
The CTCF/LncRNA‐PACERR complex recruits E1A binding protein p300 to induce pro‐tumour macrophages in pancreatic ductal adenocarcinoma via directly regulating PTGS2 expression	16
Single‐cell RNA‐seq reveals clonal diversity and prognostic genes of relapsed multiple myeloma	16
Challenges of microRNA‐based biomarkers in clinical application for cardiovascular diseases	16
Plasma levels of hsa‐miR‐3158‐3p microRNA on admission correlate with MRI findings and predict outcome in cerebral malaria	16
Trans‐omic profiling between clinical phenoms and lipidomes among patients with different subtypes of lung cancer	16
CB1R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome	16
Preparation for the challenge of heavily mutated Omicron variant	16
Accurate classification of COVID‐19 patients with different severity via machine learning	16
A natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid‐β and tau pathology	16
MiR‐378a‐3p as a putative biomarker for hepatocellular carcinoma diagnosis and prognosis: Computational screening with experimental validation	16
Functional biomarkers that distinguish between tinnitus with and without hyperacusis	16
Long‐term outcomes of relapsed/refractory double‐hit lymphoma (r/r DHL) treated with CD19/22 CAR T‐cell cocktail therapy	16
Clinical efficacy of convalescent plasma therapy on treating COVID‐19 patients: Evidence from matched study and a meta‐analysis	16
Transfer of metastatic traits via miR‐200c in extracellular vesicles derived from colorectal cancer stem cells is inhibited by atractylenolide I	16
Persistent high glucose induced EPB41L4A‐AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non‐histones	16
SUMOylation of PUM2 promotes the vasculogenic mimicry of glioma cells via regulating CEBPD	16
Molecular and physical technologies for monitoring fluid and electrolyte imbalance: A focus on cancer population	16
Destabilization of macrophage migration inhibitory factor by 4‐IPP reduces NF‐κB/P‐TEFb complex‐mediated c‐Myb transcription to suppress osteosarcoma tumourigenesis	16
Regulatory roles of HSPA6 in Actinidia chinensis Planch. root extract (acRoots)‐inhibited lung cancer proliferation	16
LDLR dysfunction induces LDL accumulation and promotes pulmonary fibrosis	15
Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma	15
Sarcopenia as a poor prognostic indicator for renal cell carcinoma patients undergoing nephrectomy in China: A multicenter study	15
Lipid raft‐disrupting miltefosine preferentially induces the death of colorectal cancer stem‐like cells	15
C/EBPδ drives key endocrine signals in the human amnion at parturition	15