OOIR: Observatory of International Research

Papers

(The median citation count of DARU-Journal of Pharmaceutical Sciences is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Hybrid derivatives containing dimethyl fumarate and benzothiazole scaffolds for the potential treatment of multiple sclerosis; in silico & in vivo study	41
Multi-functionalization of reduced graphene oxide nanosheets for tumor theragnosis: Synthesis, characterization, enzyme assay, in-silico study, radiolabeling and in vivo targeting evaluation	32
Effect of vitamins C and E on cancer survival; a systematic review	25
Colistin induced acute kidney injury in critically ill children: a prospective study utilizing RIFLE criteria	25
Dispersive micro-solid phase extraction based on two MOFs as highly effective adsorbents for analysis of nilotinib in plasma and wastewater	19
Management and control of intraocular pressure applying macitentan hydrogel film formulation: improved effect of surfactant and cosurfactant system	17
Lipid nanoparticles for gene therapy in ocular diseases	17
Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis	16
Successful treatment of acute-on-chronic liver failure secondary to alcoholic cirrhosis with glucocorticoids and albumin: a case report	16
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population	15
Stearyl amine tailored spanlastics embedded within tetronic® nanogel for boosting the repurposed anticancer potential of mebendazole: formulation, in vitro profiling, cytotoxicity assessment, and in v	13
Investigation of the potential therapeutic effect of cationic lipoplex mediated fibroblast growth factor-2 encoding plasmid DNA delivery on wound healing	13
Novel benzimidazole derivatives; synthesis, bioactivity and molecular docking study as potent urease inhibitors	12
Efficacy and expenses of succimer vs. d-penicillamine plus garlic in the treatment of lead poisoning: a retrospective cross-sectional study	12
Impact of concerning excipients on animal safety: insights for veterinary pharmacotherapy and regulatory considerations	12
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development	11
A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines	11
Co-delivery of artemisinin and metformin via PEGylated niosomal nanoparticles: potential anti-cancer effect in treatment of lung cancer cells	10
Comparative evaluation of different oral iron salts in the management of iron deficiency anemia	10
Ropivacaine suppresses the progression of renal cell carcinoma through regulating the lncRNA RMRP/EZH2/CCDC65 axis	10
Empowering the pharmaceutical industry by revolutionizing education	10
Repurposing metformin as a potential anticancer agent using in silico technique	10
The impact of Rosa dmascena Mill. on gastrointestinal disorders: a comprehensive analysis through clinical trials, systematic review, and meta-analysis	10
Electrochemical evaluation of nivolumab used in cancer treatment with differential pulse voltammetry: A novel approach with single-use pencil graphite electrode	9
Zinc-containing Mohs’ paste affects blood flow and angiogenesis suppression	9

High-performance liquid chromatography method for measuring Captopril: an empirical study on hydrogel film permeability test	8
Developing an AI-based prediction model for anaphylactic shock from injection drugs using Japanese real-world data and chemical structure-based analysis	8
Correction: Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies	8
Vancomycin- induced leukocytoclastic vasculitis in a patient with end-stage renal disease: a case report and literature review	8
Designing and psychometric evaluation of pharmacists' attitude toward ethical challenges questionnaire in pharmacy practice: A mixed‑method study	8
Alpinumisoflavone against cancer pro-angiogenic targets: In silico, In vitro, and In ovo evaluation	8
Computational Screening Using a Combination of Ligand-Based Machine Learning and Molecular Docking Methods for the Repurposing of Antivirals Targeting the SARS-CoV-2 Main Protease	8
Correction: Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/ Prdx3 pathway	7
Trends analysis and future study of the pharmaceutical industry field: a scoping review	7
A neuroprotective dose of trehalose is harmless to metabolic organs: comprehensive histopathological analysis of liver, pancreas, and kidney	7
Adrenergic receptors blockade alleviates dexamethasone-induced neurotoxicity in adult male Wistar rats: Distinct effects on β-arrestin2 expression and molecular markers of neural injury	6
Network pharmacology: a systems perspective possible underpinning approach for oral cancer treatment	6
Structure-activity relationship of pharmacophores and toxicophores: the need for clinical strategy	6
Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis	5
Fibroblast growth factor 2 reduces endoplasmic reticulum stress and apoptosis in in-vitro Non-Alcoholic Fatty Liver Disease model	5
Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer’s disease in a rat/mouse model: a systematic review	5
Electroceuticals: Unlocking the promise of therapies	5
Polymeric nanoparticles delivery circumvents bacterial resistance to ciprofloxacin	5
Mesoporous silica coated SPIONs containing curcumin and silymarin intended for breast cancer therapy	5
Colloidal and vesicular delivery system for herbal bioactive constituents	5
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment	5
Plausible mechanism of drug resistance and side-effects of COVID-19 therapeutics: a bottleneck for its eradication	5
Imiquimod as a new treatment in refractory idiopathic granulomatous mastitis: report of two cases	5
Protective and therapeutic effects of Scutellaria baicalensis and its main active ingredients baicalin and baicalein against natural toxicities and physical hazards: a review of mechanisms	5
Novel biodegradable molecularly imprinted polymer nanoparticles for drug delivery of methotrexate anti-cancer; synthesis, characterization and cellular studies	5
Solid dispersion technology as a formulation strategy for the fabrication of modified release dosage forms: A comprehensive review	5
Freeze-drying of bupivacaine lipospheres: preparation, characterization, and evaluation of anti-microbial properties	4
Intravenous magnesium sulfate for prevention of vancomycin plus piperacillin-tazobactam induced acute kidney injury in critically ill patients: An open-label, placebo-controlled, randomized clinical t	4
Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review	4
Safety assessment of the pharmacological excipient, diethylene glycol monoethyl ether (DEGEE), using in vitro and in vivo systems	4
Facile fabrication of an erythropoietin-alginate/chitosan hydrogel and evaluation of its local therapeutic effects on spinal cord injury in rats	4
Trimethoprim/sulfamethoxazole desensitization in an HIV-positive patient with previous Stevens-Johnson syndrome; a failed study	4
Investigation of the relationship between inflammation and microbiota in the intestinal tissue of female and male rats fed with fructose: Modulatory role of metformin	4
In silico screening, synthesis, characterization and biological evaluation of novel anticancer agents as potential COX-2 inhibitors	4
Comparing the efficacy of tocilizumab with corticosteroid therapy in treating COVID-19 patients: a systematic review and meta-analysis	4
A self-healable and bioadhesive acacia gum polysaccharide-based injectable hydrogel for wound healing acceleration	3
Bioassay-Guided extraction of andrographis paniculata for intervention of in-vitro prostate cancer progression in metabolic syndrome environment	3
Chidamide inhibits cell glycolysis in acute myeloid leukemia by decreasing N6-methyladenosine-related GNAS-AS1	3
Prediction of naloxone dose in opioids toxicity based on machine learning techniques (artificial intelligence)	3
Flavonoid as possible therapeutic targets against COVID-19: a scoping review of in silico studies	3
Spray freeze drying to solidify Nanosuspension of Cefixime into inhalable microparticles	3
Toxic alcohol poisoning characteristics and treatments from 2000 to 2017 at a United States regional poison center	3
Chemical compositions and repellent activity of Clerodendrum bungei Steud. essential oil against three stored product insects	3
Towards greater impact in health technology assessment: System dynamic approach for new and emerging technologies in Iran	3
Dapsone improves the vincristine-induced neuropathic nociception by modulating neuroinflammation and oxidative stress	3
Vactosertib potently improves anti-tumor properties of 5-FU for colon cancer	3
Epigenetic modulation and apoptotic induction by a novel imidazo-benzamide derivative in human lung adenocarcinoma cells	3
Metformin in the management of fibrocystic breast disease: a placebo-controlled randomized clinical trial	3
Cardiac safety profile of type II kinase inhibitors: Analysis of post-marketing reports from databases of European Medicine Agency & World Health Organization	2
An Insilico evaluation of phytocompounds from Albizia amara and Phyla nodiflora as cyclooxygenase-2 enzyme inhibitors	2

Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model	2
Utilization patterns of cardiovascular medications in patients with diabetes mellitus; a retrospective cross-sectional study, 2013-17	2
A critical overview of challenging roles of medicinal plants in improvement of wound healing technology	2
Tumor-derived exosomes encapsulating miR-34a promote apoptosis and inhibit migration and tumor progression of colorectal cancer cells under in vitro condition	2
Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery	2
Firstly electrochemical investigetions and determination of anticoagulant drug edoxaban at single-use pencil graphite electrode: an eco-friendly and cost effective voltammetric method	2
Probable ertapenem-induced encephalopathy; case report and suggested alternatives for chronic prostatitis	2
Advances in artificial intelligence-based technologies for increasing the quality of medical products	2
Calcineurin inhibitors and related medicines: a cohort study examining England’s primary care prescription changes during the COVID-19 pandemic (January 2019 to March 2021)	2
Dry powder inhaler design and particle technology in enhancing Pulmonary drug deposition: challenges and future strategies	2
Phytochemical analysis of Daphne pontica L. stems with their pro-apoptotic properties against DU-145 and LNCaP prostate cancer cells	2
New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots	2