OOIR: Observatory of International Research

Papers

(The TQCC of Therapeutic Advances in Chronic Disease is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Corrigendum to air pollution and mortality in patients with chronic obstructive pulmonary disease: a cohort study in South Korea	166
Association between galectin-3 and hepatosteatosis in a community-based cross-sectional study	33
Tenofovir is superior to entecavir in reducing HCC for patients with HBV-related compensated cirrhosis at high HCC risk scores	33
Clinical characteristics of hospitalized patients with metabolic-associated fatty liver disease–related liver cancer: data from a single center, 2010–2019	28
Association between sensitivity to thyroid hormone indices and osteoporosis in euthyroid patients with type 2 diabetes mellitus	25
Periodontal inflammation is associated with increased circulating levels of endothelial progenitor cells: a retrospective cohort study in a high vascular risk population	25
Prevalence of major non-communicable diseases and their associated risk factors in Afghanistan: a systematic review and meta-analysis	24
Bispecific antibody treatment of multiple myeloma: latest updates from the 2022 ASH annual meeting	23
Colon capsule retention in a patient with large bowel stenosis due to diverticulosis – a case report	21
Establishment of a preliminary FRAX®-based intervention threshold for rheumatoid arthritis–associated fragility fracture: a 3-year longitudinal, observational, cohort study	20
Periprocedural, short-term, and long-term outcomes following transcatheter tricuspid valve repair: a systemic review and meta-analysis	20
Associations between bone mineral density and coronary artery calcification: a systematic review and meta-analysis	19
First-line therapeutic strategy for patients with advanced non–small cell lung cancer with Leu858Arg epidermal growth factor receptor mutations: a Bayesian network meta-analysis	19
What is the role of Von Willebrand factor in chronic hepatitis B virus infection to hepatocellular carcinoma: a review article	18
Is Helicobacter pylori infection associated with pancreatic cancer? A systematic review and meta-analysis of observational studies	17
Emerging roles of macrophages in heart failure and associated treatment approaches	17
Preoperative malnutrition as an independent risk factor for the postoperative mortality in elderly Chinese individuals undergoing hip surgery: a single-center observational study	17
Remission and relapses of myasthenia gravis on long-term tacrolimus: a retrospective cross-sectional study of a Chinese cohort	16
Efficacy and safety of bisphosphonates on childhood osteoporosis secondary to chronic illness or its treatment: a meta-analysis	15
Hispanic adults with type 2 diabetes mellitus using lipid-lowering agents have better periodontal health than non-users	15
Electronic patient-reported outcomes in clinical kidney practice (ePRO Kidney): a process evaluation of educational support for clinicians	15
Complementary and alternative medicine for long COVID: a systematic review of randomized controlled trials	14
Air pollution and mortality in patients with chronic obstructive pulmonary disease: a cohort study in South Korea	13
Inheritance and innovation of the diagnosis of peripheral pulmonary lesions	12
Two-year real-world outcome data from a single tertiary centre shows reduced ustekinumab persistence in a non-bio-naïve Crohn’s disease cohort with penetrating disease, -ostomies and sarcopenia	12

Real-world safety and effectiveness of secukinumab in adult patients with moderate to severe plaque psoriasis: results from postmarketing surveillance in Korea	12
Short- and long-term effects of whole-body photobiomodulation on pain, functionality, tissue quality, central sensitisation and psychological factors in a population suffering from fibromyalgia: proto	12
Comparison of different medical treatments for primary hyperaldosteronism: a systematic review and network meta-analysis	11
Associations between age-related hearing loss, cognitive decline, and depression in Chinese centenarians and oldest-old adults	11
Comparisons of psychological distress and self-stigma among three types of substance use disorders receiving treatment-as-usual approaches: real-world data from a 9-month longitudinal study	11
Effectiveness of using calligraphic activity to treat people with schizophrenia: a randomized controlled trial in Southern Taiwan	11
Non-inferiority of 1 month versus longer dual antiplatelet therapy in patients undergoing PCI with drug-eluting stents: a systematic review and meta-analysis of randomized clinical trials	10
Effect of sodium-glucose cotransporter-2 (SGLT2) inhibitors on serum urate levels in patients with and without diabetes: a systematic review and meta-regression of 43 randomized controlled trials	10
Real-world non-interventional post-authorization safety study of long-term use of burosumab in children and adolescents with X-linked hypophosphatemia: first interim analysis	10
Latest update on the use of recombinant growth factors for periodontal regeneration: existing evidence and clinical applications	10
Morphological alterations of the hypothalamus in idiopathic intracranial hypertension	10
Sailing the ship of life: scurvy and autoimmunity . . .	9
Willingness to start insulin therapy among insulin-naïve persons with type 2 diabetes mellitus at Gulu Regional Referral Hospital, Gulu City, Uganda	9
Metformin use is associated with low risk of case fatality and disability rates in first-ever stroke patients with type 2 diabetes	9
Spleen stiffness determined by spleen-dedicated device accurately predicted esophageal varices in cirrhosis patients	9
Potential roles of gut microbiota and microbial metabolites in chronic inflammatory pain and the mechanisms of therapy drugs	9
Potential application of Klotho as a prognostic biomarker for patients with diabetic kidney disease: a meta-analysis of clinical studies	8
Hematological parameters and early-onset coronary artery disease: a retrospective case–control study based on 3366 participants	8
Therapeutic decisions in a cohort of patients with idiopathic pulmonary fibrosis: a multicenter, prospective survey from Poland	8
Chronotherapy of cardiovascular pathologies: a hopeful strategy	8
Machine learning approaches for the mortality risk assessment of patients undergoing hemodialysis	8
Fecal microbiota transplantation treatment for type 1 diabetes mellitus with malnutrition: a case report	8
A primer on common supplements and dietary measures used by patients with inflammatory bowel disease	8
Characteristics of myeloproliferative neoplasm-associated portal hypertension and endoscopic management of variceal bleeding	8
Sarcopenia and frailty combined increases the risk of mortality in patients with decompensated cirrhosis	8
Comparison of rivaroxaban-based dual antithrombotic and antiplatelet therapies for symptomatic patients with lower-extremity peripheral artery disease post-revascularization: a retrospective cohort st	8
Single-pill fixed-dose drug combinations to reduce blood pressure: the right pill for the right patient	8
A randomized, controlled trial on fenofibrate in primary biliary cholangitis patients with incomplete response to ursodeoxycholic acid	7
Deep learning-based fundus image analysis for cardiovascular disease: a review	7
Transcranial alternating current stimulation and its effects on cognition and the treatment of psychiatric disorders: a systematic review and meta-analysis	7
Eosinophilia attention, diagnosis, treatment, and awareness in physicians: a cross-sectional survey	7
Optimal treatment targets for lupus nephritis using per-protocol repeat kidney biopsy findings at 2 years and clinical data up to 5 years: a single-center observational study	7
Autoimmune colitis and neutropenia in adjuvant anti-PD-1 therapy for malignant melanoma: efficacy of Vedolizumab, a case report	7
Diagnostic value of reflux episodes in gastroesophageal reflux-induced chronic cough: a novel predictive indicator	7
Is Chinese herbal formula (nourishing Yin therapy) effective and well tolerated as an adjunct medication to hydroxychloroquine in the treatment of primary Sjögren’s syndrome? A meta-analysis of random	7
Revascularization or medical therapy for stable coronary artery disease patients with different degrees of ischemia: a systematic review and meta-analysis of the role of myocardial perfusion	6
Chemotherapy for patients with advanced lung cancer with interstitial lung disease: a prospective observational study	6
Take vedolizumab home: transition from intravenous to subcutaneous treatment	6
The need for a strategic therapeutic approach: multiple sclerosis in check	6
Lifetime risk, life expectancy, loss-of-life expectancy, and lifetime healthcare expenditures for psoriasis in Taiwan: a nationwide cohort followed from 2000 to 2017	6
Impact of cytomegalovirus on outcomes in acute severe ulcerative colitis: a retrospective observational study	6
Development of the ESEx index: a tool for predicting risk of recurrent severe COPD exacerbations	6
Can chronic kidney disease staging early predict outcome of large-artery ischemic stroke with impaired renal function?	6
The use of complementary and alternative medicine for the treatment of gastrointestinal symptoms in Long COVID: a systematic review	6
Strongyloidiasis: what every gastroenterologist needs to know	6