OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death & Disease is 84. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	452
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	400
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	376
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	374
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	355
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	267
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	253
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	244
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	233
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	215
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	203
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	192
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	188
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	186
MESH1 knockdown triggers proliferation arrest through TAZ repression	184
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	176
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	165
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	165
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	159
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2	158
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	157
Knockdown of Porf-2 restores visual function after optic nerve crush injury	157
PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis	153
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	151
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	148

CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	148
Glucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival	146
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	144
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	143
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	142
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	139
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease	136
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	136
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	134
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	133
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	131
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	130
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	129
TRAIL protects the immature lung from hyperoxic injury	127
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	127
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	126
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	126
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	125
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	122
p63, a key regulator of Ago2, links to the microRNA-144 cluster	120
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis	120
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	119
Macrophages downregulate NEDD9 to counteract S. Typhimurium- mediated FAK-AKT activation and lysosome inhibition	119
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	115
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	112
KDM1A epigenetically enhances RAD51 expression to suppress the STING-associated anti-tumor immunity in esophageal squamous cell carcinoma	110
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway	110
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	109
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	109
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	108
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	108
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	107
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	106
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	106
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	104
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	101
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	101
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	101
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	100
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	98
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	97
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	97
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	96
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	95
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	94
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	93
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	93
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	93
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	92
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	92

Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	91
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	91
Regulatory T cells in skeletal muscle repair and regeneration: recent insights	90
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	90
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	88
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	87
An integrated bioinformatic investigation of mitochondrial solute carrier family 25 (SLC25) in colon cancer followed by preliminary validation of member 5 (SLC25A5) in tumorigenesis	86
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	85
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	84