OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death & Disease is 83. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	373
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	345
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	337
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	318
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	316
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK	231
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	219
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	216
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	210
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	201
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	176
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	175
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	171
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	171
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	160
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	159
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	154
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	153
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	146
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	146
p63, a key regulator of Ago2, links to the microRNA-144 cluster	146
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	145
A novel protein encoded by circUBE4B promotes progression of esophageal squamous cell carcinoma by augmenting MAPK/ERK signaling	143
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	140
GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/β-catenin signalling pathway	139

ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	139
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	139
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	136
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	135
Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib	132
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	131
MESH1 knockdown triggers proliferation arrest through TAZ repression	131
Apatinib inhibits glioma cell malignancy in patient-derived orthotopic xenograft mouse model by targeting thrombospondin 1/myosin heavy chain 9 axis	129
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	129
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	129
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	127
The multifaceted role of Fragile X-Related Protein 1 (FXR1) in cellular processes: an updated review on cancer and clinical applications	126
Tulp1 deficiency causes early-onset retinal degeneration through affecting ciliogenesis and activating ferroptosis in zebrafish	121
TRAIL protects the immature lung from hyperoxic injury	120
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	119
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	119
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	119
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	117
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	115
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	114
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	113
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	111
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	110
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	108
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	107
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	106
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	105
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	105
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity	104
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	103
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	101
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	100
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression	99
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	99
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	99
CD36 aggravates podocyte injury by activating NLRP3 inflammasome and inhibiting autophagy in lupus nephritis	98
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	98
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway	97
SerpinB7 deficiency contributes to development of psoriasis via calcium-mediated keratinocyte differentiation dysfunction	94
CAR-T therapy dilemma and innovative design strategies for next generation	93
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	93
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	93
m6A and m5C modification of GPX4 facilitates anticancer immunity via STING activation	92
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	91
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma	91
Knockdown of Porf-2 restores visual function after optic nerve crush injury	89
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication	89
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	88
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	87
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer	86

CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	86
GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis	86
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	85
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway	84
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	84
Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1	83
Identification of multiple organ metastasis-associated hub mRNA/miRNA signatures in non-small cell lung cancer	83
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	83