OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Death & Disease is 85. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7	493
Correction: TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α	411
The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons	405
FOXA1 prevents nutrients deprivation induced autophagic cell death through inducing loss of imprinting of IGF2 in lung adenocarcinoma	394
Dominant-negative p53-overexpression in skeletal muscle induces cell death and fiber atrophy in rats	369
Correction: Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells	281
Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis	270
Correction: Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea	255
Single-cell RNA-seq and pathological phenotype reveal the functional atlas and precise roles of Sox30 in testicular cell development and differentiation	243
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation	219
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function	213
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC	205
FBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression	201
p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment	195
Defective hematopoietic differentiation of immune aplastic anemia patient-derived iPSCs	191
p63, a key regulator of Ago2, links to the microRNA-144 cluster	182
Lysine methyltransferase SMYD2 inhibits antiviral innate immunity by promoting IRF3 dephosphorylation	176
USP22 upregulates ZEB1-mediated VEGFA transcription in hepatocellular carcinoma	169
NADH:ubiquinone oxidoreductase core subunit S8 expression and functional significance in non-small cell lung cancer	169
Aurora B inhibitors promote RB hypophosphorylation and senescence independent of p53-dependent CDK2/4 inhibition	167
TRAIL protects the immature lung from hyperoxic injury	165
ATRA upregulates OTUD6B to recruit CD8+ T cells to suppress colorectal liver metastasis by stabilizing DDX5/STAT3/CXCL11 axis	164
MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma	163
Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD	162
CMTR1 promotes colorectal cancer cell growth and immune evasion by transcriptionally regulating STAT3	156

PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis	155
Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice	155
PD-L1 induces autophagy and primary resistance to EGFR–TKIs in EGFR-mutant lung adenocarcinoma via the MAPK signaling pathway	153
Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence	151
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis	148
RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling	146
Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma	145
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation	140
Endothelial ETS1 inhibition exacerbate blood–brain barrier dysfunction in multiple sclerosis through inducing endothelial-to-mesenchymal transition	137
KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1	137
Overexpression of EphB6 and EphrinB2 controls soma spacing of cortical neurons in a mutual inhibitory way	135
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation	134
Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop	133
USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis	132
Leveraging glycosylation for early detection and therapeutic target discovery in pancreatic cancer	132
ER-mitochondria association negatively affects wound healing by regulating NLRP3 activation	131
Single-cell sequencing resolves the landscape of immune cells and regulatory mechanisms in HIV-infected immune non-responders	130
The role of SPATA2 in TNF signaling, cancer, and spermatogenesis	128
NEDD4L binds the proteasome and promotes autophagy and bortezomib sensitivity in multiple myeloma	127
ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells	125
METTL16 controls Kaposi’s sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle	123
IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy	122
Ferroptotic MSCs protect mice against sepsis via promoting macrophage efferocytosis	122
Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK	119
Enhancing cell death in B-cell malignancies through targeted inhibition of Bcl-3	116
DNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation	115
PAF1 cooperates with YAP1 in metaplastic ducts to promote pancreatic cancer	114
Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma	114
Correction: NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation	113
In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy	113
Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1	112
UPF1 contributes to the maintenance of endometrial cancer stem cell phenotype by stabilizing LINC00963	111
GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila	110
Underlying mechanisms of glucocorticoid-induced β-cell death and dysfunction: a new role for glycogen synthase kinase 3	107
Hypoxia-responsive circRNAs: A novel but important participant in non-coding RNAs ushered toward tumor hypoxia	107
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer	106
Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC	105
Multi-omics prediction of axillary treatment response and tumour microenvironment alterations in lymph node-positive luminal breast cancer	105
RNA helicase DDX5 modulates sorafenib sensitivity in hepatocellular carcinoma via the Wnt/β-catenin–ferroptosis axis	104
MAGI3 enhances sensitivity to sunitinib in renal cell carcinoma by suppressing the MAS/ERK axis and serves as a prognostic marker	104
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway	104
TOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway	103
BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury	100
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhi	99
Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects	98
Mitochondria-derived H2O2 triggers liver regeneration via FoxO3a signaling pathway after partial hepatectomy in mice	96
Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α	96
FTO/IGF2BP2-mediated N6 methyladenosine modification in invasion and metastasis of thyroid carcinoma via CDH12	96
Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2	96
JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis	95

Knockdown of Porf-2 restores visual function after optic nerve crush injury	95
IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer	94
PRMT1 methylation of WTAP promotes multiple myeloma tumorigenesis by activating oxidative phosphorylation via m6A modification of NDUFS6	94
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy	92
Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model	92
CAR-T therapy dilemma and innovative design strategies for next generation	90
Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review	88
LINC00152 induced by TGF-β promotes metastasis via HuR in lung adenocarcinoma	87
The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease	87
m5C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization	86
Aryl hydrocarbon receptor dependent anti-inflammation and neuroprotective effects of tryptophan metabolites on retinal ischemia/reperfusion injury	85
Preservation of retinal structure and function in two mouse models of inherited retinal degeneration by ONL1204, an inhibitor of the Fas receptor	85